LOCUS       DBEJJE010000001        80396 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEJJE010000001 DBEJJE010000000
VERSION     DBEJJE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.01"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            556..1902
                     /gene="gdhA"
                     /locus_tag="ACL3F5_000001"
     CDS             556..1902
                     /gene="gdhA"
                     /locus_tag="ACL3F5_000001"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0513885.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(2191..5769)
                     /locus_tag="ACL3F5_000002"
     CDS             complement(2191..5769)
                     /locus_tag="ACL3F5_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0513886.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIIFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTEAHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFDDYIISDRQKIYNNLTNPNHAW
                     FYDASEIKLQQIANSYSNVWLKIFNFANQFKHSLFMNDNNIELVLFNMFLLSKNDKKI
                     KFLNYMFKSNYHFVNMNPISFLENIEESSMQSVIVSSPESEKYEWQLAYLTQLENVKN
                     EDLQTLKSILEANSLPCYFTILNFERLILKDPSLKELLIQKAGNTNFVISDFIREEEV
                     PKLINLIGVKELKFWYLINLENCQNHSYNLFQKLGEKDVDFSVEVLKKIDELRIGHSN
                     LGYMVLHSISEFRDKKEIYKKFIRFAINRPYYYYNNMIDDIIKNDSQIILEILEETNN
                     EQSAIRLVNLGVEFLENNNQKLILFNLLRAKGFGKKSFQEIHFTPYSHFYTGSHVPVL
                     ELEKELLERIKKIFETGIDYINLLLYLNKLIDCKRKAIERELEKEF"
     gene            complement(6017..6385)
                     /gene="rplL"
                     /locus_tag="ACL3F5_000003"
     CDS             complement(6017..6385)
                     /gene="rplL"
                     /locus_tag="ACL3F5_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0513887.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(6461..6961)
                     /gene="rplJ"
                     /locus_tag="ACL3F5_000004"
     CDS             complement(6461..6961)
                     /gene="rplJ"
                     /locus_tag="ACL3F5_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0513888.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(7000..7135)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(7211..8470)
                     /locus_tag="ACL3F5_000005"
     CDS             complement(7211..8470)
                     /locus_tag="ACL3F5_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0513889.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(8651..10399)
                     /locus_tag="ACL3F5_000006"
     CDS             complement(8651..10399)
                     /locus_tag="ACL3F5_000006"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0513890.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFFLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAYDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHCLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(10401..12125)
                     /locus_tag="ACL3F5_000007"
     CDS             complement(10401..12125)
                     /locus_tag="ACL3F5_000007"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0513891.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKGELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSNLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(12183..13121)
                     /gene="msrB"
                     /locus_tag="ACL3F5_000008"
     CDS             complement(12183..13121)
                     /gene="msrB"
                     /locus_tag="ACL3F5_000008"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0513892.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKTSLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(13371..14240)
                     /gene="thrB"
                     /locus_tag="ACL3F5_000009"
     CDS             complement(13371..14240)
                     /gene="thrB"
                     /locus_tag="ACL3F5_000009"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0513893.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(14242..15528)
                     /locus_tag="ACL3F5_000010"
     CDS             complement(14242..15528)
                     /locus_tag="ACL3F5_000010"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0513894.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(15679..16416)
                     /gene="mecA"
                     /locus_tag="ACL3F5_000011"
     CDS             complement(15679..16416)
                     /gene="mecA"
                     /locus_tag="ACL3F5_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0513895.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(16616..17650)
                     /locus_tag="ACL3F5_000012"
     CDS             complement(16616..17650)
                     /locus_tag="ACL3F5_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0513896.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(17679..19112)
                     /locus_tag="ACL3F5_000013"
     CDS             complement(17679..19112)
                     /locus_tag="ACL3F5_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0513897.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(19128..20114)
                     /locus_tag="ACL3F5_000014"
     CDS             complement(19128..20114)
                     /locus_tag="ACL3F5_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0513898.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(20116..21219)
                     /locus_tag="ACL3F5_000015"
     CDS             complement(20116..21219)
                     /locus_tag="ACL3F5_000015"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0513899.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(21209..22054)
                     /locus_tag="ACL3F5_000016"
     CDS             complement(21209..22054)
                     /locus_tag="ACL3F5_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0513900.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDTVIADMDKSYTEYK
                     GEYGG"
     gene            complement(22333..23607)
                     /gene="psr"
                     /locus_tag="ACL3F5_000017"
     CDS             complement(22333..23607)
                     /gene="psr"
                     /locus_tag="ACL3F5_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0513901.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(23604..24452)
                     /gene="pheA"
                     /locus_tag="ACL3F5_000018"
     CDS             complement(23604..24452)
                     /gene="pheA"
                     /locus_tag="ACL3F5_000018"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0513902.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(24449..24925)
                     /locus_tag="ACL3F5_000019"
     CDS             complement(24449..24925)
                     /locus_tag="ACL3F5_000019"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0513903.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIENRLGMSIANFFA
                     EKGETAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLRADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(24918..26201)
                     /gene="aroA"
                     /locus_tag="ACL3F5_000020"
     CDS             complement(24918..26201)
                     /gene="aroA"
                     /locus_tag="ACL3F5_000020"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0513904.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLINPNSHLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVDLDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(26293..26631)
                     /locus_tag="ACL3F5_000021"
     CDS             complement(26293..26631)
                     /locus_tag="ACL3F5_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0513905.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(26642..27745)
                     /locus_tag="ACL3F5_000022"
     CDS             complement(26642..27745)
                     /locus_tag="ACL3F5_000022"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0513906.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(27755..28921)
                     /gene="aroC"
                     /locus_tag="ACL3F5_000023"
     CDS             complement(27755..28921)
                     /gene="aroC"
                     /locus_tag="ACL3F5_000023"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0513907.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(28931..29998)
                     /gene="aroB"
                     /locus_tag="ACL3F5_000024"
     CDS             complement(28931..29998)
                     /gene="aroB"
                     /locus_tag="ACL3F5_000024"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0513908.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(30017..30871)
                     /locus_tag="ACL3F5_000025"
     CDS             complement(30017..30871)
                     /locus_tag="ACL3F5_000025"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0513909.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(30861..31538)
                     /gene="aroD"
                     /locus_tag="ACL3F5_000026"
     CDS             complement(30861..31538)
                     /gene="aroD"
                     /locus_tag="ACL3F5_000026"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0513910.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(31535..32698)
                     /locus_tag="ACL3F5_000027"
     CDS             complement(31535..32698)
                     /locus_tag="ACL3F5_000027"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0513911.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(33383..35017)
                     /locus_tag="ACL3F5_000028"
     CDS             complement(33383..35017)
                     /locus_tag="ACL3F5_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0513912.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSSMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYTFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKFKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(34998..35747)
                     /locus_tag="ACL3F5_000029"
     CDS             complement(34998..35747)
                     /locus_tag="ACL3F5_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0513913.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            35926..37380
                     /locus_tag="ACL3F5_000030"
     CDS             35926..37380
                     /locus_tag="ACL3F5_000030"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0513914.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGNNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHTNCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(37470..40088)
                     /gene="alaS"
                     /locus_tag="ACL3F5_000031"
     CDS             complement(37470..40088)
                     /gene="alaS"
                     /locus_tag="ACL3F5_000031"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0513915.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(40110..40595)
                     /locus_tag="ACL3F5_000032"
     CDS             complement(40110..40595)
                     /locus_tag="ACL3F5_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0513916.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(40870..41109)
                     /locus_tag="ACL3F5_000033"
     CDS             complement(40870..41109)
                     /locus_tag="ACL3F5_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0513917.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(41362..42432)
                     /locus_tag="ACL3F5_000034"
     CDS             complement(41362..42432)
                     /locus_tag="ACL3F5_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0513918.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGMENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(42429..43202)
                     /locus_tag="ACL3F5_000035"
     CDS             complement(42429..43202)
                     /locus_tag="ACL3F5_000035"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0513919.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(43199..44005)
                     /locus_tag="ACL3F5_000036"
     CDS             complement(43199..44005)
                     /locus_tag="ACL3F5_000036"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0513920.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(43986..45143)
                     /locus_tag="ACL3F5_000037"
     CDS             complement(43986..45143)
                     /locus_tag="ACL3F5_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0513921.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNELVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(45304..46209)
                     /gene="murB"
                     /locus_tag="ACL3F5_000038"
     CDS             complement(45304..46209)
                     /gene="murB"
                     /locus_tag="ACL3F5_000038"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0513922.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(46321..47073)
                     /locus_tag="ACL3F5_000039"
                     /pseudo
     CDS             complement(46321..47073)
                     /locus_tag="ACL3F5_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(47083..47814)
                     /gene="budA"
                     /locus_tag="ACL3F5_000040"
     CDS             complement(47083..47814)
                     /gene="budA"
                     /locus_tag="ACL3F5_000040"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0513923.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            47956..49227
                     /locus_tag="ACL3F5_000041"
     CDS             47956..49227
                     /locus_tag="ACL3F5_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0513924.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLSLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(49247..50062)
                     /locus_tag="ACL3F5_000042"
     CDS             complement(49247..50062)
                     /locus_tag="ACL3F5_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0513925.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLNMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(50219..50872)
                     /gene="phoU"
                     /locus_tag="ACL3F5_000043"
     CDS             complement(50219..50872)
                     /gene="phoU"
                     /locus_tag="ACL3F5_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0513926.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(50884..51642)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000044"
     CDS             complement(50884..51642)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000044"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0513927.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDRTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(51655..52458)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000045"
     CDS             complement(51655..52458)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000045"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0513928.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(52469..53353)
                     /gene="pstA"
                     /locus_tag="ACL3F5_000046"
     CDS             complement(52469..53353)
                     /gene="pstA"
                     /locus_tag="ACL3F5_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0513929.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(53343..54260)
                     /gene="pstC"
                     /locus_tag="ACL3F5_000047"
     CDS             complement(53343..54260)
                     /gene="pstC"
                     /locus_tag="ACL3F5_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0513930.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(54260..55138)
                     /gene="pstS"
                     /locus_tag="ACL3F5_000048"
     CDS             complement(54260..55138)
                     /gene="pstS"
                     /locus_tag="ACL3F5_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0513931.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(55712..57016)
                     /locus_tag="ACL3F5_000049"
     CDS             complement(55712..57016)
                     /locus_tag="ACL3F5_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0513932.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(57017..57790)
                     /locus_tag="ACL3F5_000050"
     CDS             complement(57017..57790)
                     /locus_tag="ACL3F5_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0513933.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(57780..58058)
                     /locus_tag="ACL3F5_000051"
     CDS             complement(57780..58058)
                     /locus_tag="ACL3F5_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0513934.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYESKVEAKKLLDS
                     YKGFKEVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(58058..58459)
                     /locus_tag="ACL3F5_000052"
     CDS             complement(58058..58459)
                     /locus_tag="ACL3F5_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0513935.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(58669..59286)
                     /locus_tag="ACL3F5_000053"
     CDS             complement(58669..59286)
                     /locus_tag="ACL3F5_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0513936.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(59276..60049)
                     /locus_tag="ACL3F5_000054"
     CDS             complement(59276..60049)
                     /locus_tag="ACL3F5_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0513937.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(60060..60797)
                     /locus_tag="ACL3F5_000055"
     CDS             complement(60060..60797)
                     /locus_tag="ACL3F5_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0513938.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(60802..61932)
                     /gene="hemW"
                     /locus_tag="ACL3F5_000056"
     CDS             complement(60802..61932)
                     /gene="hemW"
                     /locus_tag="ACL3F5_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0513939.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(62016..62405)
                     /locus_tag="ACL3F5_000057"
     CDS             complement(62016..62405)
                     /locus_tag="ACL3F5_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0513940.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(62378..62804)
                     /locus_tag="ACL3F5_000058"
                     /pseudo
     CDS             complement(62378..62804)
                     /locus_tag="ACL3F5_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(62805..63593)
                     /gene="lgt"
                     /locus_tag="ACL3F5_000059"
     CDS             complement(62805..63593)
                     /gene="lgt"
                     /locus_tag="ACL3F5_000059"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0513941.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(63586..64521)
                     /gene="hprK"
                     /locus_tag="ACL3F5_000060"
     CDS             complement(63586..64521)
                     /gene="hprK"
                     /locus_tag="ACL3F5_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0513942.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(64651..64827)
                     /gene="rpsU"
                     /locus_tag="ACL3F5_000061"
     CDS             complement(64651..64827)
                     /gene="rpsU"
                     /locus_tag="ACL3F5_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0513943.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(64967..65674)
                     /locus_tag="ACL3F5_000062"
     CDS             complement(64967..65674)
                     /locus_tag="ACL3F5_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0513944.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            65825..66853
                     /gene="queA"
                     /locus_tag="ACL3F5_000063"
     CDS             65825..66853
                     /gene="queA"
                     /locus_tag="ACL3F5_000063"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0513945.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(67504..67893)
                     /locus_tag="ACL3F5_000064"
     CDS             complement(67504..67893)
                     /locus_tag="ACL3F5_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0513946.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(67997..68653)
                     /locus_tag="ACL3F5_000065"
     CDS             complement(67997..68653)
                     /locus_tag="ACL3F5_000065"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0513947.1"
                     /translation="MFRRNLNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTE
                     QVTVDRKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYNVDGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK
                     "
     gene            complement(69354..69905)
                     /locus_tag="ACL3F5_000066"
     CDS             complement(69354..69905)
                     /locus_tag="ACL3F5_000066"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0513948.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(70255..71079)
                     /gene="nadE"
                     /locus_tag="ACL3F5_000067"
     CDS             complement(70255..71079)
                     /gene="nadE"
                     /locus_tag="ACL3F5_000067"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0513949.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(71076..72536)
                     /locus_tag="ACL3F5_000068"
     CDS             complement(71076..72536)
                     /locus_tag="ACL3F5_000068"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0513950.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(72652..73140)
                     /locus_tag="ACL3F5_000069"
     CDS             complement(72652..73140)
                     /locus_tag="ACL3F5_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0513951.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(73130..73339)
                     /locus_tag="ACL3F5_000070"
     CDS             complement(73130..73339)
                     /locus_tag="ACL3F5_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0513952.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(73725..74453)
                     /locus_tag="ACL3F5_000071"
     CDS             complement(73725..74453)
                     /locus_tag="ACL3F5_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0513953.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(74469..75339)
                     /locus_tag="ACL3F5_000072"
                     /pseudo
     CDS             complement(74469..75339)
                     /locus_tag="ACL3F5_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(75695..76981)
                     /locus_tag="ACL3F5_000073"
     CDS             complement(75695..76981)
                     /locus_tag="ACL3F5_000073"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR0513954.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMESIHYVLTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            77578..78162
                     /locus_tag="ACL3F5_000074"
                     /pseudo
     CDS             77578..78162
                     /locus_tag="ACL3F5_000074"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            78159..79337
                     /locus_tag="ACL3F5_000075"
     CDS             78159..79337
                     /locus_tag="ACL3F5_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0513955.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGVDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            79506..80132
                     /locus_tag="ACL3F5_000076"
                     /pseudo
     CDS             79506..80132
                     /locus_tag="ACL3F5_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT        24337 a        17492 c        14574 g        23993 t
ORIGIN      
        1 ttgcccatca gacgaaatat aataaattga aactagaata gtacacctct acttctaaaa
       61 cattgttaga aatcgatttg actgtcctga ttgatttgtc ctattcttgt ttcattttac
      121 tatagaacga tttgaaggcg tttatgatat ttagctgtac tagagttttt taaaagtgtt
      181 ttgatggttt ggatttcttc tttaattgat ttcatattac tattatataa tgctttttga
      241 ttttagtctg gtataaatat tgctttcctc caaaatggtc atagttttac tggcaaatct
      301 aacatatcac ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat
      361 agcataccat actttaagat tttgtcttta agaaagatat ttccaagaaa aacgttcgtt
      421 tttttatcta ttttcaaaaa aaccaaaaac tgaattgaaa gaatttttag aaaatttctg
      481 ttttttcttt acagtgaaaa aaaattctgc tataatgtct tatgtaataa aatatgacaa
      541 taaaaggaga acgatatgac atctgctaaa gaatatatcc aaagcgtgtt tgaaactgtg
      601 aaagctcgta acgggcacga ggctgaattc ctccaagctg ttgaagaatt tttcaacact
      661 ttagaacctg tatttgaaaa acaccctgag tatatcgaag aaaatatctt ggcacgtatt
      721 actgagcctg agcgcgtggt ttctttccgt gttccttggg ttgaccgtga tggaaaaatt
      781 caagtaaacc gtggttaccg tgttcaattc aactcagctg ttggaccata caaaggtgga
      841 cttcgtttcc acccaactgt aaaccaaggg atcttgaaat tcctcggatt tgaacaaatc
      901 tttaaaaatg tcttgactgg acttcctatc ggtggaggta aaggtggatc agacttcgat
      961 cctaaaggta aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat gactgaattg
     1021 caaaaacaca ttggaccatc acttgacgta cctgctggtg atatcggtgt tggtggacgt
     1081 gagattggtt acctttacgg tcaatacaag cgtcttaacc aatttgatgc tggtgtcttg
     1141 actggtaaac ctcttggatt tggtggtagc ttgattcgtc cagaagcaac tggttacggt
     1201 ttggtttact atactgaaga aatgctcaaa gctaacggta acagctttgc tggtaagaaa
     1261 gtggttattt caggttctgg taacgttgct caatacgctc ttcaaaaagc aaccgaactt
     1321 ggtgcaacag ttatctctgt ttctgactca aacggctatg ttatcgatga aaacggtatc
     1381 gacttcgatc ttttggttga tgttaaagaa aaacgtcgcg ctcgtttgac tgagtatgca
     1441 gctgagaaag caactgctac ttatcatgaa ggttctgtat ggacttacgc tggaaactat
     1501 gacattgcgc ttccatgtgc tactcaaaac gaaatcaacg gtgaagcagc taaacgtttg
     1561 gttgctcaag gcgttatctg tgtatctgaa ggtgccaaca tgccaagcaa ccttgatgcc
     1621 atcaaagttt acaaagaaaa tggtatcttc tacggacctg ccaaagctgc caacgctggt
     1681 ggtgtagccg tttcagccct tgaaatgagc caaaacagcc ttcgcctctc atggactcgt
     1741 gaagaagttg atggacgtct caaagacatc atgaccaaca tctttaacac agctaaaaca
     1801 acttcagaaa catatggtct tgataaagac taccttgcag gagctaacat tgctgccttt
     1861 gaaaatgtag caaacgctat gattgcccaa ggcgtggtat aaaaaaaaat tacggaaact
     1921 gactacccag acgggtagcc agttttttca attcctaaaa tttaagattc taataccctt
     1981 tatgcaaaaa tatagaattc tacctttttc tttatatagg ctaatgtttt taatatattt
     2041 attgtctatt tttgaaaaga caataaaact attctactat agattatcat ttcccacaat
     2101 tcataactca aacctaatat tttgttataa aacagtagat tttatttatt atatctggca
     2161 ccttaaaaag taagaaatat aaattaaaat ttaaaactct ttttccaatt ctctttcaat
     2221 agcttttcgc ttgcaatcaa ttagtttatt caagtacagt agcaagttaa tgtagtctat
     2281 acccgtttca aatatctttt taattctttc taggagttct ttttctaatt ccaacaccgg
     2341 aacatgacta ccagtataaa aatgtgaata gggagtaaaa tgtatttctt ggaatgactt
     2401 cttaccaaat cctttagctc tgagaagatt aaatagtatt agtttttgat tgttgttttc
     2461 taaaaattct acacctagat tgaccaatct aattgcagat tgctcattat ttgtttcctc
     2521 cagtatttct aatatgatct gactgtcatt ttttataata tcatcaatca tattattgta
     2581 gtagtaatat ggcctattta ttgcaaaacg gataaacttt ttataaattt ctttcttatc
     2641 tctaaattca cttatagaat gtaataccat gtatcctaaa ttggaatgac ctattctcaa
     2701 ttcatcaatt ttcttcaata cttctaccga aaaatcaaca tctttttcac ctaatttttg
     2761 aaaaagatta tagctgtgat tctgacaatt ttctaaattt attaaatacc aaaacttcaa
     2821 ctcttttact ccaattagat ttattaattt tggcacctct tcttctctta taaaatcaga
     2881 aataacaaaa tttgtattcc cagctttttg tattaacaac tcttttaaac taggatcttt
     2941 caaaatcaat ctctcaaaat ttaaaattgt aaaataacat ggtaaagaat tagcttctag
     3001 aatactcttt aatgtttgta gatcttcatt tttaacgttt tcaagttgtg ttaaataagc
     3061 aagttgccat tcatattttt ctgattctgg agaggaaaca ataacagact gcattgaact
     3121 ttcctcaata ttttctaaaa aactaatcgg attcatattt acaaaatgat agtttgattt
     3181 aaacatataa tttagaaatt taatcttttt atcatttttt gatagtaaaa acatattgaa
     3241 tagtactagc tcaatgttat tgtcattcat aaataagcta tgtttgaatt gatttgcaaa
     3301 attaaaaatt ttaagccaaa catttgaata gctatttgca atttgttgta gtttaatttc
     3361 agaagcatca taaaaccaag catggttagg atttgttaaa ttattatata ttttttgtct
     3421 gtcagaaatt atataatcat caaaaacaat cggtaaattt tctttcactt cggctttatg
     3481 caaagcataa actatttttt ctccaatcat agataagttt ttaatgtcat taaaaaataa
     3541 tttcctaata tttctcaaat ctccaaagat agtattacga tgactttctg aataggtcaa
     3601 aatttttctt ctgtaatcat atagcatttt ctcaatataa aatctagttt cacaactccc
     3661 tatattatac aaattcgcta aaagttttag tatacttcta tgatactgtt ttaatttttc
     3721 actatccggg actttatagc gcccaaaagt aaatttctct tcatgagcct ctgttctttc
     3781 gatttcaatt ttaagaaact gcttcaaaat tgtcacgatt aattcttggt tataactttt
     3841 cgtcaaatca agattagcaa gttcagaaat ggtattttca gctaaggtat aatcaatata
     3901 ttctctttct gtaaccaacc cgtagtttgc ttcaagaata ctataaacct cagaaatttt
     3961 attaggattt ttatcaaagt actttaacaa taattggaga atttgactac aatattttgt
     4021 ccgtgtagtt acaaatacaa tatttaaaac tgaatcctca atagatccct ttttatcctt
     4081 ctgattaata aaattagtct ttgtataaac ctgagactct atattatcaa ttttattttt
     4141 aacgtgtgaa attgcttcta aaggaagtaa tactccaaat tgtattaaaa acttttcttt
     4201 aagttcatca ctttcaaaat tactttcatt gtaataatat gatttaactg catcagaaac
     4261 gccttctaaa tcactctctt tcctaataaa attggaacat tgatttagta tttgaacaac
     4321 tctttggtcg tttactggat ataactcatg taaaatttct aaaattgata ttttcttgtt
     4381 aattaaaaac ttgataacta tataatcatc taatgattga tctgctatct ttacaatttt
     4441 gtcgttataa atattacaca actctctttc atgaagcttc tccactgcac tcttaaagtc
     4501 agtatttgtt atgtcagtta tttttagtaa tttattgaat tcctggttct cttctaaact
     4561 ttccagtcta atctttttta agtaagataa aataaataga gtcttttgtt ctgcataaat
     4621 aatgttgttt ttatttaaaa tttcttcata gtaatctttt aaaatatcaa tctcatcatt
     4681 aaaattagtc aaatcctgag agctagataa ctttgctgca atgactgcaa tacgcggatt
     4741 gcttttagat atcgttttta tatgttcaat ttcttgattg gtaaaatcgt ttcgagaaaa
     4801 ttgattgagt aattccttaa aattatcatc ttttataagt tctggctcaa tattattgta
     4861 cccataaact ttaatattat tgattacatc ttttttagca taatcacgta ccgtaagaat
     4921 aaaccgaata ttactagtcg tgttcagtag cccaagtgta gaaatataat tttgtgtagt
     4981 attaacatca tcaataaaaa taatattttc tttgtgtaaa tttagattgc gttttacatc
     5041 ttggtaaata tcctgattat tgctcttgac acaaataatg ttatatttat ttcgatccag
     5101 caaagagcaa atttcaattg ctaatctagt tttccctgtt ccaggcttag cagatattaa
     5161 gaagattcgt ttttcacttg atttaatggt atttataatt tcacttacat ctccaatata
     5221 gtcatttgat ataggagcat tagttttact ctcatcatga attcttatga agtcattgat
     5281 agaccaaact tgctctgtag attcactgat tgatagatac tcttttgcta aatattgaaa
     5341 atctatcttt gtaagatcat tagcaatttc attaattcca atcaattcta gatgataagg
     5401 ctcagccatt ttttctagat cttctttttg tttaattgtt atatttgaag aagtatgaca
     5461 acaaataagt ctcccaactt tatcttcagc aatattttcc tctaaaattt ttttcttaac
     5521 tgactgaatg tctccttcta atttagatat tacagactta tgggtgccat acataatata
     5581 aacatattta ccattttcga cagcgtaaga atctgggatc cctttagttg ttttatctgt
     5641 tccttcctgt gagcctaatg aaacaatatt aaaattgtat tttctactta ggtacgcgtc
     5701 acctagtttt tgaaacttcc ctccctctag ctctttaata tgttgctcaa ttttatttct
     5761 taaactcatt ataaaaacct ttccagataa gtatttcaac ataattatat cacactagtc
     5821 aaaaccataa ggtatagttt aattaacaaa ctcttgtact acgttaattt agagtagtaa
     5881 accaattata caaaaattat ttatttccta aacaactata taaaaagttt gccccttttt
     5941 aaacaaaaaa gaaaaaccgc tactcctaag aatagcggtt taatcatgtt tttaagctac
     6001 taatgtagtt gctctattat ttaagagtaa ctgaagctcc agcttcttcc aatttagctt
     6061 tgatttcttc agcttctgca gttgcaacgc cttctttaac aagtgctggt gcaccgtcaa
     6121 caagttcttt agcttcttta agaccaagac cagtgatttc acgtacaact ttgataacac
     6181 caactttttt gtcgcctgca gatgtcaatt caacgtcgaa tgaatcttta gcagcaccag
     6241 catcagctgc atcagctgca gcaacagcta caggagcagc tgcagttaca ccaaattctt
     6301 cttcgatagc ttttacaagg tcgttcaatt caaggattga agcttcttta atttcagcaa
     6361 taatgttttc aatgttcaat gccattgtta tttcctccaa ataagtttta aattttataa
     6421 tagttttttt cgtagctagg ctacgctatg tagcttaaga ttaagccgcg tcttctttgc
     6481 tttctgcaac cgctttgact gcaagagcaa cgttgcgcac tggcgcttga agtacagaaa
     6541 ggagcataga aagaagtcct tcgcggtttg gaagagttgc aagtgcaaga atctcttctt
     6601 tagatgcgac agcgccttcg attgcaccac ctttaatttc aagtgcttca gcgtttttag
     6661 aaaagtcgtt caagattttc gctggtgcga taacatcttc attagaaaat gctactgcag
     6721 atggtccaac aaatacagat gcaagatctt caagaccagc tttttcagct gcacgacgca
     6781 agattgagtt tttaataact ttatactcaa cttcgcttcc acgaagctca cgacgaagaa
     6841 ctgtatcttg ctcaactgtc aaaccacgag cgtctacaac gacgatagat gcagcagctt
     6901 tcattttttc agctactacg tcaactagtt ccgctttttt agcaataatt gcttcactca
     6961 ttagtgtgtt cacctccgta attattttgc ttggggaatt tttcaaaaag aaaaacgcgc
     7021 ccaaacctag acacgaaagt acaatacgct tctttttaca tgatacgtct tgtcctcggt
     7081 aggatattta tgagtcgagc tcccctactg tcttaggcag tttttttaaa ccgtatataa
     7141 gtatagcata gtcaaaaaaa gaatgcaaga tttttgcaaa ctttttttaa aatttttcgt
     7201 gatttttctt ttaaagttct actgtcagga cttgaccttg cttaacaacc tgttctccgg
     7261 cgatataaac atcatctaca tcactagatt taactgcata aaccaggtga gacagcatat
     7321 tttcctgagg ttggagatga attttccctt gtggttgaat gaccagaaaa tctgcttgct
     7381 tgccgacttc cagacttcct atctgatttt ccattccaag ggccttagcc ccttcgattg
     7441 tcagtacctt gagagctgtt tcgattggaa actggctggc atccccactt ttcatcttct
     7501 gaagaagagc tgcagtcctt ccttcctcaa acatatctag attgttattg gaagcaaccg
     7561 agtcagtcgc aattccgact gctactcccg ctttttggag ctggataatt ggagcaattc
     7621 ctgatgccag tttgaggtta ctgataggat tgtgggcgat agccacttga gaagatgcca
     7681 agcgttcaat ttctctctcg tttaattcga ccccgtgagc aaatacggac ggatgatcta
     7741 aataacccag ttcttcaaga aaagcaaggg ggcgtttgcc gtatcgtttg aggataattc
     7801 ctgactcctc cttggtctcc gccacatgga catggagcgg aatatttagc tcttttgcca
     7861 tttccaaact cgcttccagc aagtctctac tgcagctata cggagaatga ggtgctacca
     7921 taaccttgaa atttggattt ttatatttta agatttcgtc tatgatggat cgagttctgc
     7981 ttatagtctc agcagttgtt tctgtctctg aagaaaagag agtcggagaa aaataacaac
     8041 gcatcttgga agttttcacc acctgataaa tttgctgaat atccacacca ttgggattat
     8101 acatatcgtt aaaggttgtt gttcctgact ggagcatctc tgtcagggct tctttgaccg
     8161 cattggtagt catgtcggga gtaaactcag attctgctgg ccagatatag tcattgagcc
     8221 attcatggag attgctgtca tctcggatcc ctctcagacc tgtcattgca gaatgggtgt
     8281 gacaattgac caaaccaggc ataatccaag ctccctgata gtctataatc tgctcagctt
     8341 gctctaaaaa cgctggctta tcttgaccga catagacgat ttgagaatcc ttgactgcta
     8401 agattccatc aagataaaca tggaaatctt gatcacaagt cacgatattt acatgctgaa
     8461 agactttcat tataggctcc ttttctaaaa gacaagttgt actctcttca aaccacttca
     8521 gattcacttt gccgtaggtt gctctttgat tttcattgag tattacagta aacaattttt
     8581 ctagctattg taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa
     8641 agagaatggc ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct
     8701 ttctatccat gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa
     8761 gaattaaatc cgcatcctga atggttgaca aacagtgagc aatgatgaag cttgtgcggc
     8821 ccttcatgag ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag
     8881 aagttgcctc gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca
     8941 agagctgagc ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc
     9001 cctgtggcaa ctgttggatg aaaaagtctg cattagctgc tttggcagca gcaattactt
     9061 gctctcgact ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga
     9121 gccaggtttc ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat
     9181 aaatggattg cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga
     9241 gattgataag agttgatttt ccagcacctg taggaccaac gatggctacc ttactaccag
     9301 ctggaatatc gatagacaac tccttaatca aaattttttc aggatggtag ccaaaagaga
     9361 catgtttaaa ggaaatagct cccttaactt ggtcactggt caagacttcc ttacctgttt
     9421 cagccacttc agggctatct aagactccat agatacgctc tacgcaagcc agagcacttt
     9481 gcaactcagc tagcactgaa gaaatatcgt taaagggctt ggtgtattgc tgaacatagt
     9541 tcaaaaaagt cactaaacga ccgacggtca aggttgaacc catcatgata cgataagctc
     9601 ctactccagc taaaagggca taaatgagtg catttacaaa gcgagtcgaa ggattgaccg
     9661 ttgaagaata aaagatggct gactgagaat agcctgagta gttgtcataa gcctcacgca
     9721 atctttggat aaattctgtt tgagcattga aggactggat tatagtctgc tggctaagcg
     9781 attcttcaat caactgagtc tgaattcccc tcgtctctgt ttgcttctgg aagagatgat
     9841 aggatctctt ggcaataaag cgtgaaatca ccatggacag tggcgtcaac agcaagacta
     9901 agagagtcat gaggagatga atttggagca tggctagaat actaaccaaa atcatcaaaa
     9961 caccaatgaa aaattggtta aaaatcatgg tcaagccagc tgccaactgt tcgatgtccg
    10021 tggttacacg actaaccatc tctccactac cttgcctatc tacaaaggca atcggtaaac
    10081 gatggagctt atggatgatt cgctcccgta aatctctggt ataagagaag attagacgat
    10141 tatagaggag aggattggcc cattgtacca gagtatttcc tattaccacc aagagcatct
    10201 ggagaaaaat ctgccaaaaa actggtgatg aaccagccac taggacttgg tcaatgacct
    10261 gcccaatcag aataggtagg taaattgata agccaacttg ggcaatagtt cctagaaagg
    10321 ctaggaaaag gaagaaagga tggcttgcta aatctacggc taaacgtttg agcgtctggt
    10381 ttacagtttg tcgtttcatt ctagtcctcc tttccatgtt gggatgcatt gatttcacga
    10441 tagacttggc tggatttcat caagtcatcg tgcttgccaa cagctagcaa ctcacctttt
    10501 tccaagagga gaatctggtc cgccatctgt aaagttgagg ttcgttgaga gatcaaaatt
    10561 aagctcgtgt ttggaaaatt ttctctaata gctttcaaga gcttggactc tgtaatggta
    10621 tccagtgccg aggttgcatc atctaggatg agaaacggag cttggcgcaa gactgctcgg
    10681 gcgatagaca acctttgttt ttgtccacct gagaaatttc gcccccctgc ctcaactagg
    10741 gcatccaaaa gtccttcctt ttcactgaca aaatccttag cttgcgcaat ctccaaggcc
    10801 tgccagagtt cctggtcaga tacttcttga ttgaaaccta gagtcaagtt ggaacgaatg
    10861 gttcctttaa agagttcgac cttttgaggt acataggcaa tccaagaccg ccactgctcc
    10921 aaattaagag gactacgtcc attttgataa aggtcaatgt tccccttgtc tactggataa
    10981 agtccaagta agagttgcac caagtttgat ttaccagaac cggttccccc gatgatacct
    11041 agaatttgtc cttgagtcat atcaaaggaa atgtatctca gagaaggctg ggccgcatca
    11101 ggataggtaa aggtcaattc ttggacttgt aaaaccttat ctctggtagc ttgcttttgt
    11161 tctaactctg aatggatatc ctctggagcc tcaacaaaga cttcctcgat tcgcttggct
    11221 gagatatagg actggttgag ggaattgatc aacatggcta gcttgaccaa ttccaccaaa
    11281 atctgtaaga ggtaattgat aagagcaatg agagcacctt gactgagcac tcctccttga
    11341 attgaaatat agccttgcca gataataacg agaagagttc cattgacaat cagataggtc
    11401 agaggtgtta ataaactaga ccagaaacct gtcttttctt gtaatctagc ataaacttgg
    11461 ttaagggttt gaaaaatctg taactctcct ttttcttgac caaaagcacg aataacccgc
    11521 atcccttgca attgctggcg cgtttcctga accagttggt ccgttttctt tctgagacta
    11581 ctgtagagag gattgaccaa tcgagataac cctacaatga caatggtcaa aatggcaacc
    11641 atgactaaga accagaaagt caactcagct gagattcgat aagccataaa aatggcacca
    11701 aaaacgataa tgggcgctcg caaaaagaga cgcaggaatt gattgatacc agtctgaatc
    11761 tggtaggtat ccgaagtcaa gcgagtgacc aaactagatg ttgtcagacg gtctctgctg
    11821 tccttgggca aggaaagaat atgacgataa agatcgtttg tcaattcctt agcaaaacct
    11881 actgctgcct ttgctgagta aaattgagct atcaaggcca ctaaaacgcc aattactgca
    11941 aagataagga gcaggccaat ctgcatccag agatgacctt gatctccctg aggtaaagat
    12001 tggtcaacaa tcccagcaat caccatggga accaagagct caaaaacagc ttctaacagc
    12061 ttgaacaagg gggctaaaat tgattccttg atgtagggtt tgaagtaaga taataggtgt
    12121 ttcataaatc ccttctattc atattctaga aatgaagaaa gtgggaagcc ccactctctg
    12181 ttttatttgt ttaagtaagg caatagatag ccatatcctg ctttttccat ctcatccttg
    12241 gccacaaagc gtaaagaagc agaattgata cagtaacgga ggccgcctaa ctcccgcggt
    12301 ccatctgtga aaacatgacc caagtgagca ctgcctgaac gagaacgaac ttcaattcgc
    12361 tccattccat ggctcagatc cttgtaataa tgaatcaact ctttggaaat cggacggcta
    12421 aaacttggcc aaccacaacc tgaagcaaac ttatccttgg caaaaaagag tggctcacct
    12481 gtcgtaatat ctacataaat cccctcttca aaggtttggt cataggcatt ggtaaacgga
    12541 gcctctgtag cagcttcttg tgtgacacga taagactctt cagatagact ggtcttcaac
    12601 acctcttgac taggcttttc atagtttgct gcatcaatca atggcttatc agcatcggtt
    12661 acatcgatat gacagtaacc tgaaggattc ttcctgagat aatcttggtg gtagtcttca
    12721 gccagaatgt agtggcgtaa ttgctccact tctactgcaa tctttcgacc cagcatgcgt
    12781 tcctgctcct gcaccactgt gtagatagct ggcaaatctg cttcatcctg ataataaatc
    12841 ccagttcgat attggcgacc acggtcattc ccttgttgat tgatagatag aggatcgata
    12901 actcggaaat aataaagtaa aatctctctg agtgacactt ccttctcatc gtaaatcact
    12961 tggaccgttt ctgcatggtc tgtttccttg atcaactggt aattggtcgt ttcgacttga
    13021 ccattagcgt agccaacact ggtttctagc actccagaaa tgcgtgaaaa atattcctct
    13081 aggccccaaa aacaaccacc tgctagataa atttctgcca tctttatttc tcctttatca
    13141 cgtttttaac taatactctt cgaaaatctc ttcaaaccac gtcagcgtca ccttaccgta
    13201 ggtatgttac tgacttcgtc agttctatct gcaacctcaa aacactgttt tgagcagcct
    13261 gcggctagct tcctagtttg ctctttgatt ttcattgagt ataaacttct tttcacaaaa
    13321 aggatatgaa accctctggt caagagtttc cccatcctat cttctattct ttattttgct
    13381 tctacacgga caccttgggt atcaactctc aagtcatgca gttttccttt gaaaggttgc
    13441 ttttccaatt ctgccttaat tgttggcatc ttgtcatgag aagccagaac cataactgtc
    13501 ggcccagcac cagaaaggta ggttgcatag gccccatttt ctttggtcac ttgcttaatc
    13561 atcgcaaatt ctcttaccaa gtcctgacga tagcgctcat ggaagaggtc tccctcgatt
    13621 gcttgcccag cggtcaccat gtctcctgcc aacaaggcag caaccgctac attggcgata
    13681 gaacttgcag caacagcttc cttataagac aattttttag gcaagacact acggctgtcg
    13741 cgagtacgta attcatagtt tggaatgtaa gctagaaaat cacactctgg aaagtctgct
    13801 acgatagcag agacttgccc ttcaacagaa cttgcaataa cgagattacc ataaatggct
    13861 ggagccacat tgtcaggatg cccttcaatc ttggtcgcta actgcaattt ttcatggtct
    13921 gataagttga gttgacccag ttggttggct agttcaatcc cagcaacgat aaccgagctg
    13981 gaagaaccca aaccgcgcgc caaagggaca tcactggtca ttttcaagcg tcttggttgc
    14041 aagtctggta caatttgcaa agcgattttg agcaagagat tacgctcatc atgtggaatc
    14101 catttgccaa tctggtgttc aatcagccac tcatctcgtt cttcgcaaac ctcaatttga
    14161 agatacttgg ttacagctac accgaccgag tcaaaacctg gcccgatatt ggcactggtt
    14221 gcaggtacaa taatcttcat cttattctcc tagcaccttg aaggtattca agaggtcgaa
    14281 ttctgaaacc ttcttcaatt cagctgagac attttcaagc tgggctttat taatcttgtg
    14341 tgtgatgata acgacacgcg ccttgtcacc ctctttgcca tcttgaagga tttgcttaaa
    14401 ggaaatatct tgagcattga agatttcagc caacttcaag acctgacctt ttgagtctag
    14461 agccaagatt gagaaatagt agtttgcttt gacatcttca ggatttgcca agaccaagtc
    14521 acggctatat tcgttgaagt ctttgccaat agtaccatca ttcaaacgac gaacgatacg
    14581 gacaatatca gctacaacac ttgttgcagt tggtttttga cccgcacctg gtccgtagta
    14641 catagactca ccaataccga tagattctac aaagacagcg ttcattacgc cattcacact
    14701 agcaagtggg tgcgctttag gtaggaaggt tggagtcact tctgcagcaa tacctgaaga
    14761 agtttcctca atagaaccaa ccaatttcac tacgtaacca agctcttgag ctacagctac
    14821 gtcttctggt gtgatattgc ggattccctt gtgggctaca tcatcaaagg caatcttcat
    14881 gccaaaggca aattggctca aaataaccat cttgtaggct gcatcaatcc catctacgtc
    14941 attcgtcgga tcgctttctg caaatcctag acgttgtgct tccgcaagag catcatcgta
    15001 agaccagcct tcttccacca tcttggtcac catgaagttg gaagttccgt tgactactcc
    15061 aagcacgcgc gtaattttat cagaagccaa ggaatttgct aaagtacgaa gaattggaat
    15121 cccaccagca actgctgctt cgtagtaaag tgctaccttg ttagcttgag cgatttctag
    15181 caattctgcg ccatggacag ctaaaaggtc cttgttagca gtaacaacgt gttttccagc
    15241 ttccaaggca cgagtgataa aggttttagc aggctcaata cgccccatca attccactac
    15301 gatagtaata tcctggtctg ataaaatatc atccacattg gttacaaagt taaagtcatt
    15361 ccctgctgca agcaagcgat ttttttcatc ttcatccttg accaatacct tagcaacttt
    15421 gatatctgaa tgtgctgatt gattgatttt tcctccattt tcctttagga ggaaaggcac
    15481 accacttgca acggtaccaa atcctagtaa agcaatttta actgtcatct ttatctcctc
    15541 gaaattttct aatatagcca ttataacaga attttgtgaa aattcctatt atagtaaatc
    15601 actatttcag tataaaaaga aaaaacgaat cagacgattc gctcttctta aaatctgaaa
    15661 atagctttcc agaaaagatt agccgatttt ttgcagattg agcactgcat cgtgactcat
    15721 caagacttga ccatactctt gtaagactga gcgactgata tcactatcct ctgcaaactc
    15781 gcgcatacgg gccaacagcc aagctggata tgggcttgga tgattttcaa tatccactaa
    15841 aatggtcaaa taatagcgct cgttcatttt gtagagttca gaagtttcca tttcaaaagt
    15901 cactgtcttg gcaaaagcta ccaagtcagc caacttagca aaagaaagga tgtagtagat
    15961 gtaaggttct ttcttactct cagcttcttg ttcagcctgc tcttgctctt cttccttggc
    16021 ttcaacttgc tcaagagatt gaatggcttc gatatcatcc ttggttttgt ctgcgatgct
    16081 tttttccagg gttttgataa attcatctgg agacatttga gccaattctt ccatatctgg
    16141 caaatccgat aagtcttcaa aatctagatt ttggtcaatc tttgacttgg tcacaaagac
    16201 atctacctta tcaggttttg gagtcacacg gaagctcaac atgcctgtat ccagaaagct
    16261 atcaggcatc tctagctcat ccaagatagc ataaaagaac tcttctgttt tttcttgagg
    16321 aacgagaaag tcagcaatct ccattccacg atccatcaaa tcctctaaag acatcgtgat
    16381 ttttaaagtt gtatcactaa tttgtttcat tttcattgct agtaacctca tactttcagt
    16441 tctatctatt atactagatt tttacgattt tatcaaaaga aggctcctct atgcggatag
    16501 attttcccaa gggtctttct ataggagact ccaaaagaaa atttctgcag acagatagaa
    16561 aaagccttca aaatcggctc ttagccgact ttgaagacct tatacatcag aatacttata
    16621 atttaaaggt tgctacaccg aggatagaac gatttaagtt tctgagaatt tgaagacttt
    16681 gctcaaattt cttataacga gtcactccgt actcttcaac aagaaggact gtatctcttt
    16741 ccaaaagaga tgatacatcc tgtaaatcta caaaatgcat tccttttaaa gcttcttgac
    16801 tctgtttcaa tttatctagg atagctttat ttgagctaac gatggtcaat tcctgtccag
    16861 tatttttgta tgacaaaaca tctgctaggt tagcaattgt tgtaatctct gttacaaaat
    16921 caatttgata ctgagaaaaa tcacctactc tattgattgt tggattaaag agataaacta
    16981 acacatttcc catcacaacc aaaatcacac aaaccactcc aataacaact aaacgaagaa
    17041 tcagattttt cacatttaag ccaagcgctg tttcaccatt tgcgttcaat tctttagagt
    17101 tgatggtttc cagtttttca attttcacat ttgcataggc atgtttaaat ttctcaatca
    17161 acccatcaat ttttttctct aacaagtcat tggcatcttt acttgatgtc aaaattttca
    17221 caccaacccc tgcatcgtca atcatatagt agacggtcaa ttttttccac caatagtcat
    17281 tcgttgaatt tttcaaggtt gtttctgtcg tgtctaattc actggcaatt tttttcaact
    17341 cactgggttc tacatcattg aaaagataag ctccattcaa attaccatca atcaatttcc
    17401 cataaaaatc actataacca ccaatttgat gattcaaaat cgttttggcc gaatcttctg
    17461 gaggagtgat tttatagata agataagttg aataacttgt tgtatctttg acagtgtttt
    17521 tattcctaac tgctttaatt gtaaatggta cagcaatgag agcaaataaa gcgatgagag
    17581 ctaaaatatt tgcttttcgc tttttataaa gatttgcaaa caaatcagct actgaataat
    17641 gttcaaacat gatttttttc tcctttgttt agtagatact agttttcctt tgtaagcatt
    17701 tttgctacaa atataatcac aagaacaatt ccccagaatt gcattgtaaa taaattgaag
    17761 aaactttctg aaaagctgct tcttggcata aagaatagat tattcaagat gagtagggat
    17821 aaagcaaata ggattgtcct tgagcgatag gctacttgca gcatggctat aaataatacg
    17881 ccgagtaaga aactaagcag aaagactcca atcataccat agtcggtata caactccatg
    17941 atataactac ttccgatacc atgccctttc aagtattcct tgttcaagac aagataggat
    18001 agattgtggg cataactatt actatcaata gctagttcca cactattggt tgtatgttca
    18061 aaggcttttc ctccgaaaat ggctcccaaa ctcccccttg caaaataatc aagaacagga
    18121 ccaaaagtaa aattacggaa atctcggtaa gggaggctac tgttaaatag aaaacctcga
    18181 gccagaacac caaaactagt cccttgttta tagataaagt caagtaagat atcccagaaa
    18241 cctgtatggg aaacttggac attatcccgt acataattga gtactcccat cgctaacatg
    18301 agaataggag aacctacaaa aatcgctaac ttttctttaa acccaatcca ttttcctttt
    18361 tcagtttgct cccgcataaa gtaataaaca aaagcaaata aaatacttaa aataaaggga
    18421 tttcgtgtcc caattgccaa atgaatagta ttagctgcaa taaaggagac aagcactgct
    18481 gtggcctgca atttctttgg cttggttgcc agatacatac acattgcata gaccgtaaag
    18541 gtagacaaaa tgtaggtaaa ataaggcagt ttactttcaa aatttgcata gtaggcatag
    18601 taggaagtct gcaaacgata caagagccgt tcaaataacc gaatgaaata gaaaggatag
    18661 gttagaagaa aaactcctag tgatacaaag cgtaaccgct tgatataaac ctcttttaga
    18721 gaatttccta tatttgctac ttttattttc ttcctagcta tgaagtaacg agccagaatg
    18781 cctcctgtgg tcaagcccag aatcgaaacc atgacaacta taaaggcaaa acgataggct
    18841 attggatgat aggtatccaa agcaccatcc ctaaaataat caatggtcgg tcttgatacc
    18901 agaaatacaa aaatggttaa atagaaaata aaatggatta agtaatactt gatatcattc
    18961 caacaagcaa ttaagctact aaccaacaag aacaataaag tagaaagtaa gctaacatta
    19021 ttattattaa acagatacac aattccactt actagcgtca aggcataact gactatggtc
    19081 aaactaaata ataatcgttt cccatcaatc acttggtcac ccccgttcta atgtaatttt
    19141 ttagattttt caatattttt cagtaataag aatcgatata aggaaatatt tatgaatagg
    19201 gccaaagcac taattcttct ccccttacgg aaaattggat tcctagaaat agcaaaggca
    19261 tggcctttta aaaaacgatg aatctgagaa taggctttaa actgtttata ctgatcatct
    19321 agcaacatct tatccagaat aaagaagtgg gcataggcca atctgaaaaa agcgacctct
    19381 ttcaagtcag gatagttttt cacaacttca ttataaaact tttggtagat atcaatatag
    19441 gctaaatcct tctctgcata gggtttggtc gtaatactat cccctctatg gaaatagtaa
    19501 taatagggtt tagtattaac cacatacttc ttggccaact tgattaaatc aaaatggtaa
    19561 taggcatctt cgtaaatcaa ccccttagga aaggataggg cagttgcaat ctgtctcttg
    19621 attagcttat tgcaaatcgt cccaggtatt ttttcaccta tgaggtattc ctttagaaat
    19681 gtttgagaat cacagacaaa atagtcatcc tgattggctg actgtgggct ttcatcatta
    19741 gcatagacat tcatgacacc acagctcgaa acatccgcat cttcttgaac taattgctca
    19801 tataagctct gaatcatttc tggatggata taatcatctg agtcaataaa aatcagataa
    19861 tccccgtgag cctgcttcat cccatcattt cgtgcttgcg acaatccttc gttcttttta
    19921 tgaagcactg acaccctgtc atcttgttca gcgattgaat cacacaagcg accactttca
    19981 tctgttgcac catcatcaac aagaataatt tccagatttt gataggtctg cttctgaatg
    20041 gaagctatcg atttttctag gtactgcgcc acattataga ctggcacaat cacactaatt
    20101 aatgcagttt ccatgctact cctctaatag tttttctact tgttcgattt gttttgtaat
    20161 tgtaaattgt tgaatgaatt ggctagcctc atcgacatca aagtttgagg cagaagtcat
    20221 gtaattagta atcgcctgag ctgcctcttg attgctctca atgatttgtc caaatcgtcc
    20281 ttcttgggat aattcctcag cccctccaac gtccgtagag ataaaaggga gtcccagact
    20341 caaggcctcc acatacactc caggaaaacc ttcttgttta gacatagaca aaagaacttt
    20401 cgtctgagat agatactgat aaggattttt ttgataacca aggaaatgta catagtcctc
    20461 aatcccatac tctttgactc gttttttcag ttcctcttcc atatcaccag ccccgataaa
    20521 atagagatga tagttttttc cctcttggtg taataatcgt atcacttcca ctacacggtc
    20581 agaaccctta ttttcctcaa tccgtccgat agtacagata ctttgaggag caatctcgat
    20641 atcgatcttc tcttgagatt tttctagaat agtctgaaaa tcatatccat tgtagattgt
    20701 ctgtaattta gaagtataat ctggataaac ttccttgata gaattgctgg tcttttttga
    20761 aatccctaca attgtattcg cagcatccaa ctggcttcta tgtgattctc ttttagagct
    20821 atccttaaga agttcttcaa tacttccatg aatccaagat atcttcttga cttctcttct
    20881 tttagagaac aacagtggtg gattcataat ggtaaaagaa acttcaacat cataatcatc
    20941 ttttacaagc aaacgacgag ccagtcttgg aaaataaatt ctcattctcc acaaaaaagc
    21001 tcgtaaccat ctggtttggc gataatcttg aagggatttt aaaatgcgta catgctttgg
    21061 aacagattca tatcccttgt caaagtgctc catttcaaga atatcaatat catacttttc
    21121 tggatccaga tttgaaacaa tggttgatag aatcttctct gcaccacctc caagagaaaa
    21181 agaccacata aaaaataaga tttttttctt agccaccata ttctcccttg tattctgtat
    21241 aagacttatc catatcagca atgacagtat catgatgcgg tacctgcttg tctgctggtg
    21301 gaggcgtcat ataatcccca aaagcagttc tgagatagac atcatagccg attggaatag
    21361 gcatctctgt tccttcaaat ggcaagaaaa gattgtcttc aaaagatgtg attgggtact
    21421 tgtttctcat gtagccagga cctgagcata attctgtaat gccatcacaa tcagccaaat
    21481 catacttagt catttctttc tcagcttttt tccagatgcg ataacggaga gattttggag
    21541 tcaaacccag taaaatgcga cttccccatt tcatgagagc accatgcttt tctggaatag
    21601 tttgcgcaca aaagagtgaa taaatcaagg cccaacgaac ctgttttttc cgctcagctg
    21661 gatttttcgg ataataatcc aaaggcaaaa catccaaggc cagaccatgt ggcaaatcca
    21721 aatcctgctg ataaggcttg atacaggtgg tttccttgtc acgaatggta ataaaaagat
    21781 tacgatcaac aaaattcttg tgactctttg acaagaaata acgttcatct gcataacgag
    21841 gccataattc tgctaatttc tcataatctt tacgaggcat aaaaaagtct aggtcgtcgt
    21901 cccaaggaat aaatcccttg tttcgaaggg caccaatagc gcctccgcca cagagataac
    21961 agagcaaatc atgttcttta caaaaggcca caaaatattc agccatctcc agactacgag
    22021 cctgaattgc ttttaaatca gtcatattgt tcattattct ttctatcgta tcgtttcatt
    22081 ataccacaaa caaggggtga aaatctattg cagactgtaa aaaatcaaag cctgactgct
    22141 atccaaatag ctatcaaact ttgatttttc tgtcttatac tcttcgaaaa tctcttcaaa
    22201 ccacgtcagc ttcaccttgc cgtaggtata ggtaactgac ttcgtcagtc ttatctacaa
    22261 cctcaaaact gtgtttttag cagcctgcgg ctagcttcct agtttgcact ttaattttca
    22321 ttgagtatta tcttatctca agcccatttg agcgagcttg gtttgatatt tgttttgatc
    22381 aaccagcaag cccaagcctc cataaacatc ataggcatct acccagtcac ccagttctgg
    22441 aatcgtcaat ttttcaatac cattttttgc tccatccaaa acagataaac cgtttgttag
    22501 gaggaaagta taggggacgt tggttgaggt catagcaaaa acctttccaa gagcttcaga
    22561 accagtgaaa agtttagtgg gatctttaat ttgctctaaa attgctgtta aaacttgttg
    22621 ctgtcttttt gtacggccgt aatccgcctc atcatcatca cggaaacgag cataattgag
    22681 cagggtcgag ccattcatct gctgttttcc gactttaatg gtttgggttg gagactcagt
    22741 ctcggtagcg tataaatcat ctccgactgt agcttctgtt aggggacgcc cattcaatgt
    22801 tgaaaattga gcatcaatcg tcaccccatc agggaaaagc gtgtcaatcg ctgtggcaaa
    22861 ggcctggaaa tcaaccaagg cgtagtactt aatgtccaag tcaaaattat ctttcaagac
    22921 ttggcgaacc atttctgccc ctttttgccc ctcttgttct cctaactcgt aggctacgtt
    22981 taacttgtta tctgtctgtt ttctaccatt aatcacttga ctataaccat ctatatagac
    23041 caaattatca cgcatgaaac tgactagctt cattttctta tctgagcccc cgacatttaa
    23101 taccataata gagtcagttc gtgtctcaac actgttctgg ccgattcgac catcagtacc
    23161 catgattaaa atattaactc catctctagt gtcctgacca ttaaagactt ctacttgagc
    23221 tgcccgggca tcagcagttt tctttgcgct agcatcttgg taaccacgca aaaacatgaa
    23281 taccatggcc aaagccacac agaccaaaag tgaaaaaatc accataaaaa ttcgtttaag
    23341 acggagcttc cgtcttttct tttttggagg gaaagagagt gcttgtgatt tggattgtga
    23401 gcgactccgg ttcgcatagc ttggtaagtc aacctgctct tctctttctt gttccaagct
    23461 agagctacta tttcccctag caagagttag cttttcttgc aaataggcaa actcattttt
    23521 ttctctctca ttgaggtagt gaatattttt tagcaaataa tcataacgca actgctcatg
    23581 atgacttaag ggattttctt tactcatctt ctctcctttc catggtctga tattggataa
    23641 ataggatagg cacccagaat tttatactgg attccaatcg cttctaattc tttttgggca
    23701 aagtggacca agtccttatc ggtataatcc acatcgataa tgaaaaagta ttcacccagt
    23761 gctgtcttga gtggacgact ttcaattttt gtcaagtcaa ttcctcgcca agcaaaggtc
    23821 gacagggcct tataaagtgc acctggaagg ttgtcaggta atgtcaaggc caaactcatc
    23881 ttttcagttt gtgcttgcaa gggaatacta ggcttttcag ctcctagaac ccagaaacgt
    23941 gtgaaattgg cttccatttc ctgaatatcc tcggcaatca gttccaatcc atattcttca
    24001 gcagaacttc taggtgcaac tgctgcaaag ggctggtctg gatgttcgga aataaaacgg
    24061 gccgcataag ctgtactagc tgttacctcg atttgagcct ctggatattg ttcatcgatg
    24121 aatttctttc cttgagccaa ggcctgtgga tgtgaaaaaa tcttttcaat cttagtatgg
    24181 cctggaacca ccatcaactg ctgatgaata ggctgaacga tttctgctac tgcttggatg
    24241 tgagcctgat gaaaaagata gtccaaggtt tcatgaacac taccctcaat agaattttca
    24301 actggcacca cagaatagtt cactaatcct tgctcataag ccttgatgac atctgtaatg
    24361 ttggcaaaag cctgcaattc ctcatgagga aaagctgtct gcacaacgtg gtgtgaaaat
    24421 gatcccttgg gacctagata agctattttc atcttagttc ctctataatt tcctctgggc
    24481 ttagcttggt cacatccaaa acccgactag ccacttcctc ataccaagcc tgtctttctt
    24541 ggaaaatagc tactagttct tccttgctat tatttagaaa aagcggtcgc tgattgtcct
    24601 tatcagctgc gatacgttgg tagagggttt caaaatctgc tctcaggtag atgttatctg
    24661 tattagtctt gagtaagtca cgatttctct gagaaataac cactcctcct ccagttgaca
    24721 cgacttggtc tgtttgtagt aaatcagcta ggacttctga ttctacctga cgaaaggctg
    24781 tttctccctt ttcagcgaaa aaattcgcaa tggacatacc taggcgattc tcaatcagag
    24841 catccatatc aaggtaatta gggtccaagc ctcttgcaat agtcgatttt ccagccccca
    24901 taaaccctaa taacacctta gccatgaatc aagctctcca aatcatcaaa gaaactagga
    24961 tagctggtat tgatggcttc tgcacggtca agatccacct ctccatctgc aaccaagagg
    25021 gctgcgatag ctgtcatcat gccgatacgg tggtcaccaa acgtattgac tctagcaccg
    25081 tgaagagctg atttcccttt gataatcatc ccatctgccg taggagtaat atctgctccc
    25141 atactattta aggcgtctgc cacaacctga atacggtctg tttccttgac cttgagctcc
    25201 tcagcatcct tgataactgt tacaccttgg gcttgagtcg caagcagggc aataatgggc
    25261 aattcatcaa tcaatcgtgg aatcaaagcg ccaccaattt ctgttccttt caagtcagaa
    25321 gactcaacag tcaaggtaga agatttagcg actggatcga tttcagtaac ttctaatttt
    25381 ccacccatgg cacgaatgac atcaataata ccagtacgcg tttcgttgat tcccacattc
    25441 tgcagcacta gatgagaatt tggattaatc aaacctgcga ctaaccaaaa ggctgcactg
    25501 gaaatatctc ctggtacgac caccttctgt cctgtcaatt tttgtggccc ttggactgtg
    25561 attttcttac cgtccacact taaatgacca ccaaattgtt gcaacatatc ttcagtatga
    25621 ttacgtgtgc actctttttc gataataact gactccccct tagcttgtaa ggctgcaaac
    25681 atcaaggctg acttgacttg ggcagaggca attggcaact cataatgaat aggtcttagg
    25741 tttttcgtcc cttttaagcg aaggggaggc aagtctcgtt cagtttgccc tgagatgctg
    25801 acgcccattt ttttcagtgg aagggtcaca cggtccatag gacgtttgga aagactatca
    25861 tctccaaaca tctctacttc gaaatctgca ccagcaagga cacctgaaat caggcgaatc
    25921 gaggtgccag aatttcccat attaagggca ttttgcggcg cttttaagcc agccatgcct
    25981 acaccttgaa tggtaataac cccatcttta tcctcaattt caacaccaag gtcacgaaaa
    26041 acctgcatgg tcgaaagaac gtcttcacct cgcagaatat cataaacctt ggtctcaccc
    26101 tcagccaaac ttccaaagat aatggaacgg tggctgatag acttgtcacc tgggacgcgg
    26161 atactaccat gtaaatggcg aatatttgtt tttagtttca tactggacct catacttgca
    26221 atacttttac ctattttatc ataaaaagcc agaaattcct taaaaattcc tgactttagg
    26281 atagttcttt tcttatttca gcaattctga aactggttcg aaaacaattt tttcaatgtc
    26341 agaaaggtaa atggccaatt gttgttgctt ggtaaagaat tctgacaaga ggctatttcc
    26401 ttgaatctgt ttaccaaagc cttccatctt agcttggaag gacgcatctg gcatttgacc
    26461 tgtctgtgct agtttttgaa tttcctcttg aaaggcaaga tattctgtaa agattttgct
    26521 tgcctcagca tctgctgcaa tcgcatcttt agctgcttta acagccttgt attctggtaa
    26581 tccgcgtaga ccgcgactga gttcgtttgc actatcgtaa atatttgaca tgttcttctc
    26641 cttatttaat gacgactgta tagtcggtat tttttgttat gagatgctcg gctctttcca
    26701 agtcttgagc atttttaaat gaaatttgta ggattccgtg aatatcctca cgattttcct
    26761 cgttgatgtg gatgttaacc aaggaagtcc cacgtagcag ttccaaaatc cgcaggatga
    26821 catcttcttc atcaggaacg tcaacataga ggtcgtaaga gctatccaca ccaccacgct
    26881 tatggatttc catggtctgg cgttgttcac gcgcttggtt aaaaaagttc caaatttgct
    26941 cttcatctcc cttactaatg gcctgaccaa tcgattccaa acgttccttg aaatcctcaa
    27001 ttctatccag aatggtctcg ctattggaca agagaatgga ggtccacatt cctggctcgc
    27061 tttccgcaat tcgggtcata tctcgaaaac cacctgccgc aaagcgcctt gccatctcat
    27121 gctcttgagc atagaccgca gtctgctcca tgagactaga agccaaaata tgaggaaaat
    27181 ggctaatctg agaagtgaca cgatcatgct ccttggcatc aatctcgata aaacgagcat
    27241 gaagacctga aagcagatcc ttcatttcct taagcgtgtc ctgacttgtc aggcttgaag
    27301 gtgtaaagat ataataggca ttttcaaaaa gattgacatc tgccgaagca gcccctgtct
    27361 tgtgactacc agccatggga tgggccccga caaagcgaac agacttgcca gccaaatact
    27421 gctccgccgc atccacaatg gttgacttgg tcgaaccagc atctgaaata ataacgcctt
    27481 ctcgcaaatc caaattggcc aactccttaa tgaaagcaat agtttgtttg attggcaagc
    27541 tgaggataat gacatctgcc aaaggagcaa aactagcaaa atcatccgtt gcacggtcaa
    27601 tcatgccttc tttcaaggcg atatctctcg aagcttgact acgattataa cctaaaattt
    27661 cataatctgg atgatcgcgt ttgataccaa gtgccataga ggctccaatc aacccaagac
    27721 ctgcgatata gattgttttt gccataggaa ctccttaata gttctttgta tagtctcggt
    27781 gtttggctac cgcttctttt agttcctcaa gattatctga tgagaatttt tcgaggatct
    27841 cttgcgccag aaccgttgct acaactgctt ccatgaccat tcctgcagct ggaagagcag
    27901 tcggatcact tctctccacg gttgccttgt aaggttcgtg ggtttcgata tccacactca
    27961 taagaggttt ataaagagta ggaatgggtt tcatgacccc acgaacaacg atgggttgtc
    28021 cattagtcat accaccttca aaaccaccta gattattggt acggcgagta taaccgtctt
    28081 ctttagacca gagaatttca tccataactt ggctgccttt acgataacca gcctcaaagc
    28141 caagaccaaa ttccacccct ttaaaggcat tgatagagac aacagcttga gccaatcttg
    28201 catccaattt tctatcccat tggacatagg aaccaagacc aactggaacg cctccgacga
    28261 ctgtctccac aaccccaccg atggtatcac catcacgttt gatttggtca atatagtcct
    28321 tgatttcctg ttctcgttct tggttgacaa tagaaacttc agactgggca gctctttgct
    28381 taatttcagc gactgtcaga ttttcaggaa catcgatttc cttgccacca aagaccacga
    28441 catggttggc aatctccata tccagctcag ccaagaggcg tttggctact gcaccaactg
    28501 ccacccgcat ggtggtttca cgagctgatg aacgctccaa agaatttcgc aaatcatcaa
    28561 aacggtactt aatcccccca accaaatcgg catgacctgg gcgaggatga gtaattttcc
    28621 gcttgctttt aaggcggtct tcaatgtcct ccgcagacat gatgtccagc catttctggt
    28681 ggtccttatt gatgacatcc atagtaatag gcgcccctgt cgtcttcccg tggcgaacgc
    28741 ccgaagtaaa gacaacctgg tcactctcaa tcttcatacg accaccacga ccgtagccac
    28801 cctgacggcg tctaaggtcc tcattgatat cctcagctgt caatggaagt ccagctggaa
    28861 ttccctcaat aatagctgtt agacgggggc cgtgtgattc tcctgcagtt aaatatctca
    28921 tacactctcc ttattttacc aagtagtctt tcatctcttc cagagaaact gggtgaatga
    28981 tcgctgaacc aagctctgac accaagacca atttcaaggt gttaccacgc gttttcttgt
    29041 catgagtaag agcctgataa agcttgtcaa cttcccaatt ttcatagtca acaggcaagc
    29101 cgaatttctg acacatctct gtgatagatt gggtaatgcc agctggcatg aggccttttt
    29161 cctcagcaac cttggaaatc tgtaccattc ccatggcaac agcctctcca tgcatgacct
    29221 tgccataacc ggcagtcgct tcgatggcat ggccaatagt gtggccaaaa ttgaggtaaa
    29281 gacgaatacc attgtccaac tcatcttcaa ccaccatctt gcgcttcacc tgacaagaat
    29341 gttcaatcaa ggtctctgca tgttccaaaa tgctctcaac agaaccattc agttccgtca
    29401 agagagccca cagttctgga tcctcaatca agccatactt gataacttca cccatccctt
    29461 caatcaactc tctttttccg agggtttcaa gaacaagtgg atcaatcaga accccatctg
    29521 gttgggcaaa ggtccccacc atatttttag caaatggtgt gttaacgcct gtctttccac
    29581 cgatagaaga atcaacctga gctgtcaaac tagtcggaat ctgaacaaag tgaatacccc
    29641 gcatataggt agaggctaca aatccagcca ggtccccaac aacgccacca ccaagagcaa
    29701 cgattccatc gctacgagtc agaccttgct tgactagaaa ttcatagact ttctgaacag
    29761 tagttaaatt ctttctttct tcaccttcta agaaatcaaa aacagctacc tgaaaaccag
    29821 catcttctag gctgagcttg accttctctg catagagaga ggctacatgg ttatctgtca
    29881 caatgactac cttttgcggt tgccagagtt ctcgcaacca ctgaccagcc tgggccatac
    29941 aacctttttc aatctgaata tcataaggat gatgaggaat atcgattctg attttcatag
    30001 gagagtctcc ctttctttat tggtattttt ctgttaaaga ctgccaaatc tcttctgtcg
    30061 gcatttcctt gcctgtccac agttgaaaag cttctgcagc ttgatagagt aacattccca
    30121 gaccattgac tgctggattg ccctgacttc tagcccattt caaaaacggt gtttcaaagg
    30181 gttggtatat gatatctgca actaagagag tttctggtaa gactatgttt tcaggaacag
    30241 gagaggattg gccatccatg cccacactgg tggcattaac tagcaaatcc gactcggcaa
    30301 tccttgcttg cagttcagaa acatattcta aagcacacaa atccacttta aaacctgtct
    30361 gctcctgtaa cttgtctagg taaggtcttg ttttttccat agaaacggaa cgaacaaaga
    30421 ccgaaatctg actgacgcca tccaaaatag cctgtgccaa gattgattta gccgcaccac
    30481 ctgcacccag cagggtcatc tttttacctg aaattgtaaa agaaggcaag cacttaaaaa
    30541 atcccttgcc atctgtatta tatccaatta aattgccatt ctcattgaca accgtattaa
    30601 ccgcaccaat caagcgcgct tcatcgctca gcttatccaa ataaggaatc acctgctcct
    30661 tatagggcat ggacagattg atgccaaaca tctggtagcg acgaatattg gccactgttt
    30721 ctaccaagtc actcgcttca atctcccaag ccacataagc accgttggta gctgtcgcct
    30781 caaaggctct attgtggatg aagggagaaa tagaatgctt aataggattg gcaacaactg
    30841 cagctaaacg tgtatagcca tcaagcttca tccaaaatct ccctgatttt tttcatgcta
    30901 gctagagaaa tctgcccagg ggcactaacc tcatccagac tggcaaaaga ccaactcgaa
    30961 ccagtcacat ccgcagtgat acgagagacc ttgcccacct tacccataga aatggtcaca
    31021 tattcctgtt caggattgag ggttttaaag cctcgtgtat agttcatcaa gtctaagaca
    31081 tcctgctccg tgtgagccat caccgcaacc ttaacaagtt ttggatttag gatcgtcaac
    31141 tctgacaaga tttccatcat gttctcaggt gtttcttgga aattatggta actcaaaaca
    31201 agatttggga agtccagcat ttcctcaaaa acatccttgt agctatagta ctcaaaatca
    31261 atatagtctg gttgatagaa ttgcgcaact tccttgatta gatggatata ctcttctgga
    31321 gaaaggtcga tttctccacc ttcggagcga gttcgtagcg tgaaaaccaa ctcacggcct
    31381 gcgaattttt caaaaatggc tggagctacc tgcaaaatcg cttctttagg cagatagtcg
    31441 gcacgccatt caatgatgtc ggcatccagg tacctcgtgg catccagagc ctgagcctcc
    31501 tctaaacttc ttggcattac tgaaacgatt aatttcattt actaaccttc atactaatca
    31561 ccttgaggta attactactt tcatcttttt tattataggc aaaatctgct ggaagaccat
    31621 atttgtttaa aatctggtaa cttcttcctg caaagccttt atcaatttgt tctgtaaatt
    31681 tctgacggga aacattggca gcattagtac tggcaatgat aatccctccc ggatttaaaa
    31741 tctcaagact ctgggaaatc aacttgtgat aatccttggc cacagagaaa gtttgttttt
    31801 tattccgagc aaagctaggc ggatctagga caatcacatc gtaggtcaag tctttgcgtt
    31861 tggcatattt gaaatactca aagacatcca tgactataaa acgatgctcg tctgtgctga
    31921 gcccatttgc ctgaaaatgc gcttgagaca attctcgtga acgtttggct agatcaacag
    31981 aagttgtctg gctagctcct cccatggccg cagctactga aaaagccgct gtgtaggaaa
    32041 acatattgag caaggattta cccatagcca agccgtcaac taaactaccg cgaacctcat
    32101 gctggtctag gaaaattcct gtcatcaagc catcattcat aaagacttga tacaggacac
    32161 cattttctaa aacagtgaaa aagtcaggtg cttcttgacc ataaacatgg gcagattcat
    32221 agtccaaacc cttaaagcgg attttctcat aagcccctaa aacctcaggg aaaacctgtc
    32281 taaaggcttc tgatatagtc tgacgaatct gataaacata agagttatac caagaaaaga
    32341 cggcgtagtc gccataaagg tccactgtca gacccccaaa gccatctccc tcttgattaa
    32401 agagacgaaa ggcagttgtc aaatcatctt gatagtaggc gtttctcttt tctttggctt
    32461 ttctaaacaa cgtttcaaag aaagtttgat tgaaggccac cttgtctttg ctgacaaacc
    32521 agcccaagcc cttgttttgc tgagaaaggt aggcagtccc aagaaagttt ccttcctgac
    32581 cctgcacctc tacttcctga tccttaagat tgacattctc aagatcactg gcttctagta
    32641 aaactagccc cttagcaagc ttcttttcaa cccttttgct gactcttatt ctattcatag
    32701 ctaccattat atcaaacttt tagacaattc tcaaaaaaga aactaccctt gcttttttac
    32761 tcttctttta aaaaatggta tactagactt cctgcaaaac taggaagtaa atgtgtaaga
    32821 atcacaataa aaaatgctct tccgtcttgg aggagcattt ctttttatca acgaaaatca
    32881 aatagcaaac tatgaaacta gcctcaggtt aactgtgaga ttataggtag agaggttgaa
    32941 tcagcaatat gtgtctgtca aatttagtga caaaggtagt agaagaaaga tgaagaaata
    33001 aatcagcttc agtagatatc tggaaaattt gattttatag agaagccttt tgttacaaac
    33061 tcaatatact atcaataaat aatattatag aagcaacaat aattataatt tcacctatct
    33121 gcatcattct atttcgaatt ctaaatatat gttctatcaa gaatacttgg aacacacaca
    33181 ttatagtaat taacgttttt gaaattgaaa aatatccaaa taaataaact ataaacaaca
    33241 aaaatagaac tatgttatat ttcttattca aaacattcct ccctatattt ttgattacca
    33301 atcttaatca tttacagcta cattctaaca aactataaaa gcgtttgtcg aattgaattt
    33361 atcaagcaag cgaccaacca gctcatcttt tttctatttc tgccaatatg cgtgacaggt
    33421 aataatgata gccaaaaata gcaagagcaa gcaggaggat aagagctcct actcccaagc
    33481 tgatggcaag gatagtggag agagactgaa ccaagaatat gctcccaatt acaagggcca
    33541 tcaggattgc actataaata aacaataaaa ctatggcgac tatgccattt gaacgattca
    33601 ccaggtccgt aatgctactc caattggttg acagattttt aacgtcctta aagtaatggt
    33661 ggcaagaaag gatgacactg gcaaggatcc atgccacaat aaggtaaatc atcgaaatga
    33721 tgggcaagcc tagatataga gaaagaccaa gcaaagtcag aactggtaaa aaggactgga
    33781 cagcatatat aatccaaaat ttcactttca cataacgagc aaagtcaaag ggtaaactct
    33841 taagaaaatc aacattttcc ctctccaagg acaaggcaat tgaatgcagg ctggtgatat
    33901 tgttattgac aactgctata aacactccta caaaaaacaa gggtaaccag tatggaggat
    33961 gaatgtctgg aactatctga gaatctcgga ttttggaaat cagaccgatc atcatgagat
    34021 aaggaaagaa agcacttgta aaaagcactg taaccacgcc agtaccctgt cccaagaggg
    34081 tgaggtggta gcgtaaaacc atgcggaaaa atcccttttt agtggttgaa attctctcct
    34141 tgctgcgacg ttcttttttg aacttctcct cactattaag caggatcacg tcataaaaac
    34201 gaggaaggac cttctttttg gtcagataaa gcaggaagag agttagtcct atccaagcga
    34261 gcagacccaa tatggcttct gtcgaaaaag gctccactgc tattttgtaa aagatatgaa
    34321 gaggataaag gagaaatgga atgtctctaa ctttgtcaac aatacttcca aaagtcgact
    34381 gaagaaagaa gataaatatt aaaggtatga gaactcctat cccaatcatc acattcgaaa
    34441 aaatagactg atactttctg aagaccctag tttgagccaa gaaatgcact gccactacca
    34501 tcactagagc cacagagaca aataataagg tcaaggacag tagcatcaaa ggcaaaccca
    34561 gccatagaga aggagctagc ctaatgtaga ggaccagaaa ataagctagg attggtacaa
    34621 ttccagttag agctggcaaa aggacagaca gtcctttagc aattataatc tctgattctt
    34681 taaaggtata gggcctatac gatatcaaat ccttactctc ataaaagaca ttgtaaaagg
    34741 ccgttaaaga agttgaaaag gcaatcacta gtaaaatagc aatcatcgaa ctaaaataaa
    34801 taggtatttc ctcaaaagga aaatgaatgg ctatattact aaaacagatg atcatcaaga
    34861 gactggaaaa aatgtaagaa cttaagactc tagcggaaac atttactttt ttcccaggat
    34921 tcttagcctg cttctttcgt agattagcca gattagcttc ttgagatgaa taaaggatat
    34981 tgatatcaac taatttttta atgaccttga gacgcatccg caacctcctc ttttctacca
    35041 gcaagactaa ggtagatact ttccaaagac tggtctgggt aatcttttct caagtcctct
    35101 acactaccac aataaatcaa atgccccttt ttcaaaatgg caatccgatc acagacttgc
    35161 tctgccacct ctaggacatg agttgaaaac aagactgtct tccctttttg tgcatgttcc
    35221 ttcatcatct gtttcaaatc aaaggcagcc tggggatcca aaccagtcaa gggttcatcc
    35281 aagacccaaa tatcgggatc agacaagagt gctccgatga caaagacttt ctgacgcatt
    35341 ccgtgagaaa gagtttcaat aacctgatag cgattttcag caaaatcaaa aacgttcaat
    35401 agcctagcta gactagcctc caagtcagat ctactcagat cataggatga ggcgatcaat
    35461 tcccaaaatt cattggccgt taagcgtaaa aataagtcag gcgagtctgc tacgtagcca
    35521 atctttcgtt taatagccaa gcgattttcc gataactcct gaccgtctac caaaatacga
    35581 ccactgctgg gtgaaatgat actgactagg gattttatag tggtcgattt tccagcccca
    35641 ttatgaccaa tcaagcccat aatctctcca ttttcaatct gcaaattgag attactcaag
    35701 gcctttttat caccatacaa cttactaaca ttttgaaatt caatcatggg acaactccta
    35761 tctttatctg tattatatat cgctatacta gcactttgat acaaaaaaat caatacttta
    35821 ttttaagtag ttaaaatagt ttccttctat cttacgcaaa cgtttgcgct aatagatact
    35881 ttatgataga ataaagaaca agattgacaa gtaagaggaa acattatgca aaatcaaaca
    35941 ctcatgcaat actttgaatg gtatctgccc cacgacggtc aacactggac ccgtctggct
    36001 gaaaatgctc cacacctagc tcatctgggg atcagtcacg tctggatgcc accagccttc
    36061 aaggcaacca acgaaaaaga tgtcggctat ggggtctatg acttatttga cttaggagag
    36121 ttcaaccaaa aagggactgt ccgcaccaag tatggtttca aagaagacta tcttcaagcc
    36181 attcaagccc ttaaagcgca gggaattcaa cctatggccg atgtggttct caaccacaag
    36241 gctgctgctg atcacaggga agcctttcaa gttattgaag tggatcctgt agaccgtaca
    36301 gttgaacttg gagaaccctt caccatcaat ggctggacta gttttacctt cgatggtcgc
    36361 caagatacct acaatgactt ccactggcac tggtaccact tcacaggtac agactatgat
    36421 gccaaacgcc gtaagtctgg gatttatctg atccaaggga acaacaaggg ctgggctaac
    36481 gaggaattgg tcgataacga aaacggaaac tacgactacc tcatgtatgc cgacctagac
    36541 tttaaacatc ctgaagtcat ccaaaacatc tatgactggg ctgattggtt catggaaacg
    36601 actggtgtag ctggtttccg tttggatgcc gttaagcata ttgactcttt ctttatgcgc
    36661 aacttcatcc gcgatatgaa ggaaaaatac ggtgacgatt tctatgtttt tggtgaattt
    36721 tggaacccag acaaggaagc caatctggac tatctcgaaa aaacggaaga acactttgac
    36781 cttgtcgatg ttcgtctcca tcagaatctc tttgaagcca gtcaagctgg cgcaaactat
    36841 gaccttcgtg gcattttcac agatagcctg gttgaactca agcctgacaa ggctgtgact
    36901 tttgtcgaca accacgatac ccaacgagga caagcccttg agtctaccgt tgaagaatgg
    36961 ttcaagccag cagcctatgc cctcattttg ttacgccaag acggccttcc atgtgtcttt
    37021 tacggagact actatgggat ttcaggccag tatgctcaag aagatttcaa agaaatcctt
    37081 gaccgcctcc tagccatccg aaaagatttg gcctatggag aacaaaatga ctactttgac
    37141 catactaact gtatcggttg ggtacgttca ggtgctgaaa atcaatcccc aatcgcagtc
    37201 cttatctcaa atgaccaaga aaacagcaag tcaatgtttg tcggtcaaga atggactaat
    37261 caaacctttg tagatttact tggtaaccac caaggtcaag ttacaattga tgaggaaggt
    37321 tatggacaat tccctgtctc agctagatcc gtaagtgtct gggcagtcaa taccatctaa
    37381 tagctcataa taaccaagct aggtccaagc ggatttggct tttttgtatt cacaaaaaga
    37441 cctacccaaa tggatagatc tttacttgat tacaatttac ctgctactgc atccaacaat
    37501 tcttggatct taggttggtt gcttcctcct gccatggcca tgtctggttt accaccacca
    37561 cgtccatcga tgattggtgc taattctttg acaaggtttc ctgcatgaag gtcttttgtc
    37621 ttgcttgcta caaggacatt gactttgtca ccgatagcgg caactaggac aagaagatca
    37681 gagtagtctt tttgtttcca gttatctgca aaggtacgaa gggcacctgc atcggataca
    37741 gacacttgac tagcaatgta acgatgaccg ttgacttcct taacatcttt gaagatatcg
    37801 cctgcggctg cagctgcggc tttttctttc aactcagcat tttctttttg aagttgacga
    37861 agttgttctt gaagtccttc taccttgtga ggtacttcct tgacttgagg tgctttcaag
    37921 gttgctgcga cagctttaag agcatcctct tgttcacgat aggcttcaaa ggcttcctta
    37981 ccagtcactg ccaagatacg gcgagttcct gaaccgattc cttcttcttt gacaattttg
    38041 aagagaccaa tctcagaagt gttgccaaca tgagtaccac cacaaagttc aatagagtag
    38101 tcaccaatag tcacgacacg aacttccttg ccgtatttct caccaaagag ggccatcgct
    38161 cccatttctt tagcagtgtc aatatccgtt tcaactgtct taacttcaag agcttcccag
    38221 attttttcgt tgacttgctg ttcaatcgca cgcaattctt cagcagttac agcttggaag
    38281 tgggtaaagt caaagcgaag gaattcaact tcgttaagag atcctgcctg tgttgcgtgg
    38341 tttccaagga tattgtgaag ggcagcgtga agcaaatgag tcgcagtgtg gtttttcatg
    38401 acacggtgac ggcgattgct atcaattgcc aaggtatatt cttggttcaa ggcaagcggt
    38461 gcaaggactt caactgtatg aagggcttga ccatttgggg ctttctgaac attggtcaca
    38521 gtagccacaa ccttacctga ctcatccaag atttgtccgt ggtcagcgac ctgtccaccc
    38581 atttcagcat agaatggcgt ttccgcaaag ataagtgagg tagttccttc tgatacagct
    38641 tctacttctg cattgtcagc aacgatagcc accaatttag aagacaattg gctagcattg
    38701 tggttgaaga cactttctac agtgatgttt tgaagagttt cattttgcat acccattgag
    38761 ccacccttga cagctgacgc acgcgcgcgt tcttgttgtt ctttcatggc tgcttcaaaa
    38821 ccttcacggt ctacagtcat accagcctct tcagcaattt cttcagtcaa ttcaactggg
    38881 aatccgtatg tatcatagag tttaaagaca tcttgaccag caatgacaga ttgacctttt
    38941 tctttcaagt ctgccacaat gccttgggca aagtgttgac ctgagtgaag ggtacgggca
    39001 aatgattctt cttcgctctt aacgattttc tcaataaagt cacgtttctc aagcacttct
    39061 gggtagtagc tttccatgat ttttccaaca gttggaacga gtttgtaaag gaaaggctcg
    39121 ttgataccca atttttgacc atgcatagaa gcacgacgga gaagacgacg aagaacataa
    39181 ccacgacctt catttcctgg aagggcacca tcaccgatag caaatgaaag agaacgaatg
    39241 tggtctgcga taaccttgaa gctcatgttg tcgccatctt ggtcataaac cttaccagac
    39301 aatttctcga cttcacggat aatcggcatg aagaggtccg tttcaaagtt ggtcttagcc
    39361 ccttggataa cggccaccaa acgctccaaa ccagcgcccg tatcaatgtt cttatgtggc
    39421 aattccttgt attcgctacg aggaacagca gggtctgcgt taaattgtga caaaacgatg
    39481 ttccagattt cgatgtaacg gtcgttttca atatcttctg caagcaggcg aagaccgata
    39541 ttttctgggt caaaggcttc cccacggtca aagaaaatct ctgtatctgg tccagaaggt
    39601 cccgcaccaa tttcccagaa gttgtcctca attggaatca agtgacttgg atccactccc
    39661 acttcaatcc agcggttgta agaatcttta tcatctggat agtaagtcat gtaaagtttc
    39721 tcagctggga agtcaaacca ttcagggctt gtcaaaagct cataagccca agtgatggct
    39781 tcatcacgga agtaatcccc gatagagaag ttccccaaca tttcaaacat ggtatggtga
    39841 cgcgcagtct tccctacgtt ttcgatgtcg ttggtacgga tagccttttg ggcattggta
    39901 atacgtggat tttcagggat aatggtcccg tcaaagtatt tcttgagggt tgctacccca
    39961 gagttgatcc acaaaagagt tgggtcattt acaggaacca aacttactga tggttctact
    40021 gagtgacctt tggtcgccca gaaatcaagc cacatttggc gtacttgtgc actagatagt
    40081 tgtttcatat tgtctcctta tttacttgtt taatgtgatt ggctttccag catttccaca
    40141 tagtcaatcg cgacacagag ggaaatgact aggtctgcat aagcgtcttc aagaaccgtt
    40201 acggtatagg tagaggtcag atggaagagt tccttcttaa tttccgcaat caactgatcg
    40261 cgatcatcca gcaatttgaa attcaaatcc cagatattgc cctcgatacg aagacctaga
    40321 ttatcaaact catacttatc tcgccaaaag gtcaacttct tacgaatgac aaaactcgag
    40381 ccatcccgaa gctgaatctc aaaacgagga agcaaggtca agatttcttt actgatctga
    40441 ctgacttgtt caccagccgc atcatagatg gtaaaagttt tgggaatctt aaaaaatgat
    40501 ccctccacct gataggcaat ttctcccctg tcatccttga tagcgaagcg ttcgcctcca
    40561 agacgaaact tttgtttgac aagaaatgtt ttcatcaaca cctccaaaaa tcaaaagaca
    40621 agctcatatc acgaagggcg aaaaaccgcg gtaccacctt cattcaatga acttgtcatt
    40681 ctcttgttct tatgcaattg tatgattgag tagcatgact ttctagctta gatggctcgc
    40741 agcaccgcca tttctctgga ctaagacaag tgaaaattaa ttctcaactt tcttattata
    40801 acgttttttt aagcttgcgt caactggaaa tgatctccgt tgaattagac caattcccta
    40861 catctctgat tactttttca ggatatattt tttcttacta ccgtttttct ttttatccca
    40921 aattttcata ttactaaaca cagctactag aatatttcca aatataaagg tgcctatcac
    40981 ccaatatatg gactcagttg ttaggtattg tcgatccaag ccatccttta aatggaatag
    41041 tataacagtt tggttaacaa tcataaaggt tggccagaaa ctttttttga aaaaagtaga
    41101 cattttcatt atttgttgcc gctttctgta aggttaatac tcaataaaaa tcaaaaagca
    41161 aactaggaag ctagcctcaa gctgtacttg agtacggcaa ggcaacgctg acatggtttg
    41221 aagagtatag gcttagtata ctactaggca agcaaataag caaataaaca actagaatag
    41281 aaaaagatag ggctctaaaa actgacttct attccttaaa aacgaaccag cttgactgat
    41341 tcgccttctt acgtttatct cctacttccg atacatttta aactgtagga agaggtcgct
    41401 atatttccct gtccatttat ggtcaaattt ctcataaact tctaggtgtt tcatggtttc
    41461 aacatcggga tagaaggcct tatcttcctt tgtttcctct gggagcaatt ccttcgctgg
    41521 taggtttggt gttgaatagc cgacatactc cgcattttgg agagcatttt caggtttcaa
    41581 cataaagttg ataaaggcat aggctgagtt ttggttttta actgttttgg gaatgaccat
    41641 attgtcaaac caaagattgc tggcctctgt cggtaccaca taacgtagat tttcattttt
    41701 ttctaacatt tggctggctt caccagagaa ggtcacgccg attgcaacat tattctgaat
    41761 catatagccc ttcatctcgt ccgcaacgat agccttgata tttggagtca gtttgtagag
    41821 cttatccact gtctcttcca actgctgcag atccttggag ttgaggctgt agccgaggga
    41881 attgagtcct agtcccagca cctcacgcgc cccatcaaag agcatgatag aattcttata
    41941 ctccggcttc caaaggtcat cccaatgctc aggcgcttca tctaccatgg tttcgttgta
    42001 gacaattcct aaggttcccc agaagtaagg gatggagaat ttattacctg ggtcaaagga
    42061 ctggttgaga aactctggtc cgatattttc cattccttca atttttgaat aatcaagcgg
    42121 aaccaagagg tcttcgtcct tcatcttgtt aatcatgtat tcacttggaa tggcaatatc
    42181 gtaggtcgtt ccaccctgct ttatcttagt gtacatggct tcgttggagt caaaagtctc
    42241 gtactgaact tgaattcctg tttcttctgt aaactgagtc aagagttcag gatcgatata
    42301 gtctccccag ttatagataa ccaatttttg actatctcga ctattgattt tactatctaa
    42361 atgagtcgca attccccaca agacaaggat aatcgctgca attcctgcta aaaatgaata
    42421 gatttttttc atgcttgctc ctccttctca cgagagataa agtaataacc tacaactagg
    42481 ataatactaa agagaaagac tagagcagaa agggcattga tttctagcga aatccccttg
    42541 cgagcacgag agtaaatctc gactgatagg gttgaaaagc catttcctgt tacaaagaag
    42601 gtcacggcaa agtcatctaa cgaataggtg aaggccatga aataaccagc aatgatagac
    42661 ggagtcaggt aaggaagcat gatttcctta aacatctgaa attgactagc tcccaagtca
    42721 taggccgcat gaatcatgtc gccattcatt tccttgagtc gaggcaagac catcaagacc
    42781 acgataggaa tggagaaggc cacgtgacta gatagaacgg tcaaaaagcc aagtgaaaac
    42841 ttgagttggg taaagagaat caagaagcta gcaccaatca taacgtcagg cgcaaccatg
    42901 aggatattat tgagtgatag aaaggcttct tggtatttct tacgagactg gtagatgtaa
    42961 atggcaccaa aagtcccgat aatggtcgct atcaaggctg ataggaaggc caagaaaaat
    43021 gtctgagcca aaatcagcat gagtctccca tctccaaaca tggtttcaaa gtgagtccag
    43081 ctaaaacctg taaagctatt catatcatca ccagcattaa aggcatagcc aatcaagtaa
    43141 aagataggca ggtagaggac cagaaagacc agtcccagat aaaggttggc aaattttttc
    43201 atcgttctct cctttcctta gtcacccaca tggtgatgaa catggtcagg atgagaatca
    43261 caccgatagt tgaacccata ccatagttgt cattggttag aaaattctgc tcaatagccg
    43321 tccccaaggt gataacgcgg ttcccaccaa tcaaacgggt cagcatgaag agactcaaac
    43381 ttgggataaa gaccgactga accccacttc gcacaccgtt catagataga gggaagatga
    43441 catgacggaa ggtctcccac ttagttgcac caaggtcgta actagcattg atgagattat
    43501 tatccatatc gtctaagaca ttgaaaatcg gcaaaatcat aaaggggagc tcgatgtagc
    43561 ttgcgacaaa gataaatgag aaatcagtaa atagcaactg ctgtgaacca attccgataa
    43621 attccaagaa ttggttaata gagccattct gaccaaaaat cccgataaag gcataagcct
    43681 taagaagaag gttgatccaa gttggcagaa taatcagcat aatccagagt tgacggtgtt
    43741 tgagacgggt caaaaagagg gccgtcggat aactgataag cagtgtcaca aaggtcacaa
    43801 tgcctgcata aagcactgag ttgaaactca ttttaagata ggtcaagttt tgtgacgcaa
    43861 agtaagattt gtaattttct aaactgaact ggccttcgat gttgaaaaag gattgaccga
    43921 aaatcaagac caagggtgcc aatacaaaga gcgcaatcca aagcatgtag ggtactacaa
    43981 agagtttaga gcttgttttc ttcatctctt tcctcctcga ttgcattgat caaacctgct
    44041 tcttgctctt cgatttctac gtactcctca atacgagcat cgaactcttc ttcggtttca
    44101 ttgagacgca tgatgtggat gtcttctggt tcaaagtcca gaccgatttc ctcacccacg
    44161 atggccttac gggttgagtg gatcatccat tcatttccaa gttcgtcata ggcgataatt
    44221 tcataatgca ccccacggaa gagctgggta tcgaccttaa cttgaagctt gccttcttca
    44281 ggaagggtaa tgcgcaagtc ctctggacga ataacgacct caacaagttc atttggcttc
    44341 atcccaccat caaccgcttc aaagcgtttg ccgttaaatt cgaccaagta gtcctcaatc
    44401 atggtacctg gcaagatgtt tgactccccg ataaaggtgg caacaaagtg gttgattggc
    44461 tcatcgtaga tgtccacagg ggttccagac tggacaatct cgccatcatt cataacgaaa
    44521 atccagtcac tcatggcaag agcttcttcc tgatcgtgag tgacaaagac aaaggtaatg
    44581 cccaatcgtt gttgcagttc acgcagttcg tactgcatgt ctgttcttaa tttcaagtcc
    44641 agcgctgaca agggctcatc caacaaaacc acacggggtt ggttgatgat agcacgggcg
    44701 atagccacac gctgacgttg tcctccagaa agtttgcgga tggaacgttt ttcataacct
    44761 tccaactgaa ccatcttgag aacttccgct acacgttgct cgatttcttt cttatcaatg
    44821 ttacgcaagc gaagtggaaa ggcaacattt tcaaacacat tcatatgtgg gaacaaggca
    44881 taggattgga agacagtatg tacgtcgcgc ttgttggttg gaatatcatt gatacgaaca
    44941 ccgtctagca tgatatctcc tgtcgtcgca tccagtaaac ctgcaataat gtttaggata
    45001 gttgatttcc ccgaaccaga tgcacctaga agggtgtaga atttcccttc ttccaactca
    45061 aagttgatgt ctttgagaac cttggtgttg ctgtcttcaa aaactttaga gacgtttttg
    45121 aattcgataa ttggtttttt caattggcat aaattccttc tttttcatag attaaccgat
    45181 cggggctctg tcaggtcccc actacctctt gcagggagta aaaccacctg catacatctt
    45241 cgctaccgat aggctttcac ccccctttcc atgacatagc agcagctttt caaatacagc
    45301 ttcctacttg ctttcaccca agatccggac ttctctttca agcgtaatac ctgagtgttc
    45361 cttgactttt tcgataaccg attggatcaa gtcctcgtag tctttggccg ttccatctgc
    45421 gacattgatc ataaatcctg catgcttttc tgacacttct acgccaccga tacgatagcc
    45481 tttcaagcca gcttctgaaa ttaactgacc tgcaaaatgc ccgactggac gcttaaagac
    45541 cgagccacaa gatgggtatt ccaaaggttg cttgagttca cgtaggtgcg tcaagcggtc
    45601 catttcctgc ttgataacct gatgggttcc tggggctagg gcaaatttaa ctgacaagac
    45661 aactgcacca gactcctgaa tagctgaatg gcggtaacca aaagccaagt ctttagcaga
    45721 cagggtttcg atttctccat ccttggtcaa gaccttacaa gactgcaata tgtgagcaat
    45781 ctcgccacca taggcacccg cattcataaa gacagcaccg ccaacgcttc ctggaatacc
    45841 acaagcaaac tcaaagccag tcaaactatg acggagggca atgcgagttg tttcaatcaa
    45901 gttagcccca gcttctgctt caatggtata gccatcaaca gaaacgttat tgagcttgtc
    45961 acacaagatg acaaatccac gaatcccacc atcacgaacg atgatattgc ttgcattgcc
    46021 aagaaccatc caagggatat tttcttggtt ggcaaatttc acaacgcgag ccaactcaaa
    46081 acgatttcgt ggaaagacca aataatcagc ctctccacct acttttgtat aactatagct
    46141 atgcaagggt tcctgaaaac ggatatcaat tccttctaag atttcaagca ttttttctct
    46201 tacagacatg tcactcttcc ttttacaaaa ttcattccat tataccattt ttagagacat
    46261 ttgacgacca taaaaatacc ttgtttggat tttgcataag aaaaagaggt tccccccttt
    46321 ttatgatttt ttacaaaaga tttccttggt tccataggca accagaacga gctccagtgc
    46381 tagaatcact tcaaccaaga ctggatttgt caaccagcct acttggaaaa gagatggtgc
    46441 cagatcaaag aaggcatgca agccataggc tgctaggaga taaatccatt tcttctggcg
    46501 aacagcttgg taaacccaaa ctgtcaaaag taattggaaa ccaagcgcca agattcgctc
    46561 aaaaccaagc aaataaatct gccagaccga aagtgactga atggttttta acatattttc
    46621 agacagtaat tgcataacct gtggattctg agtttgaact gccgaaagaa cgatgtaaag
    46681 attgagtaaa ctaataaggc ctagaaaaat caactccaag ccaccatgcc ctaggccata
    46741 ggccaaggcg tctgcctttt ccaaacttct ctttttctcc aaccatttga agaaaacaag
    46801 acgagccgtt tcctcaaaaa atgctaccat ggctaggcca tagataatat agataagcgg
    46861 atgaacttac aagagggcaa tactaccgtc tttttgagga tgcaaaatca agatatgcac
    46921 cagtttttcc aaaatctgcg aagagacaaa gaaagcgact gcacccaagt ccaagacagc
    46981 tagattaatc tggtatttct ttttggcaaa ccaaatgctt cctatcagaa aagctagcaa
    47041 cagcaacatg gtaataatga tatgaatggt cattttcttc tcctattctg ccttttcaat
    47101 atcttttttc atctcgtcaa cattgaactt agcaaacaag tattgacggt cttggactgg
    47161 gaaacgttgg tccaactggt caactgctcc cacctcgata atgccttcct tgatgacaaa
    47221 atccatgaca tgtccaccga aggtcaaatc atctgatatg aagtgcagat ggtagcctgc
    47281 cacactgacc ccatggaaaa tctcaggcgt ccagaaacca acaatagtcc ccacaacatt
    47341 gtcacgacta tattccggtt gatgggttgc gacatcagca aacttggtat cgggtgttga
    47401 cttaggaatc atacgcacat gcatatgtga aaattccccc cgaatcttga tagagcggaa
    47461 aagattttcc ccatcataat aagactcaat tcgttcttcc aattccttgt ctgtcatctc
    47521 aaagcgctgg cggaaaatga cctctgcctg atgcggtact actgctgcat aaggaataag
    47581 ggcatctggt gacacttcca caatttctgg ctggtctcct gaccctttgg cctgataagc
    47641 cttgccatcc aagacaatca attccccatc aatagaatcc aaggttccca aaccaaggtc
    47701 accatgctct agcaattctc ccactgtcat ggtaccacca taaaggccag ccatcaaggc
    47761 tccaagagta ttgtattgaa ataatttcac tggttcctgc acgttcttat ccattcactt
    47821 tcttgtctgt tattctataa atcttactcc taagtatacc acatttgccc ctagatgtga
    47881 acgagagaaa cgctctagac attgccaaga aggaaaaaaa agggtacaat gtaacaaaat
    47941 caagggaggt ctggaatgaa gaaacaaagc aagtacaaag aggtcgtttc ctatctgaaa
    48001 aatggtatcg agtctggacg atttccgacg ggtagtcgcc tgccttctat ccgtcaactg
    48061 agccttgact ttcactgcag caaggacacc attcaacgag ccctgctgga attacggcac
    48121 gaacaatatc tctatgccaa gcctcagagt ggctactatg tattagaaca agggcaacat
    48181 caagacctag aaatcgaggt taccgacgaa catgccagtg cctatgacga tttccgactc
    48241 tgtgtcaatg aaaccttgat tggccgagaa aactacctct tcaactacta tgacaatcaa
    48301 gaaggattag aagacctaag acagtccatt cacaaactcc tctttgagca agctctctac
    48361 tgcaaggcta accaactagt actgacttct ggaacccaac aagccttgtt tatcctctct
    48421 caaatatcct ttcctagaca agccaaggaa atcttggtgg aacagccaac ctaccatcgg
    48481 atgaatcgcc tcttgattgc acaggggctg gactatcaaa cgattgaacg aggcattgat
    48541 gggattgact tggaggagct ggaaggccac ttcaaaacag gaaaaattaa atttttctac
    48601 accattccta gatttcacta tcctctggga cattcctatt ctgagcagga caaacgatct
    48661 attcttaact tagctgccaa gtatgatgtc tatatcgtag aggacgatta tctgggtgat
    48721 ttggactcca agaagggcca aaccttccac tatcttgata cagaggagcg tgtcatttat
    48781 atcaagtcct tctcgaccag cctttttcct gcccttcgta ttacagcact cattcttcca
    48841 aatgctatca aagaagcatt tgtggcctac aaaaatatcc tagactacga cagcaacctc
    48901 attatgcaaa aggccctgtc actctatatt gacagtcaat tgtttgaaaa aaatcgtttg
    48961 gctcgcttga ccaatcatga atcttaccaa aaacaaatcg aggaaaggat aactaaaaca
    49021 ccttgtcccc ttcctcatta tcccctacac gatggtttat tgctagacct gagacagtat
    49081 cctaaaatcg ccagtctcaa acacagtcaa ctgagcttgg acttctttga agaggcctat
    49141 ttaagcacct gtccttatca atttgccaag gtgtccctag acaatctgga aaatgtttta
    49201 aactatttaa aagcagaatt ggaatgacat ccaactctgc tttttcttat tcttcaactt
    49261 cagttaaact tgctgctttt tcaagatagc tttggtaagt tccttcatcc ttaagttttt
    49321 ggatgacctt gtctaccact tctttcaaat catcactatt ttttctaaga gcaacggcat
    49381 tggcgtcgcc gtccttcata ttcaagctga cagttgcgac agctaagcca gcgtttttag
    49441 cagcataact aagtgcaaca ggctcatcca tatgaacagc atctactttt ccagcctgca
    49501 attcattgac tgcttcaccc atattagtta gggaagttaa ttgagctttt ggcaattgtt
    49561 ccttgaccat tgattctgga acagtccctt tttgggctgc aatattagca ctttctaggc
    49621 tagttaaatc cttgtatttt tccacatcag ccttacgaac caagaaacta atcttgtttt
    49681 catagtatgg gattgaaaaa tcaaagactt cttttctctc gtcagtagca ctaattcctg
    49741 caactgctag gtcagcctta ccagtttgaa gactggtcaa aacattgtca aaactcatgc
    49801 ttgagatttc caacttaacc ccaagttcat cagcgatagc ctgagccatg tcgatgtctg
    49861 caccgactac ctggttcttt ccatcaacca atgattgaaa ttcaaagggt gcatagtcag
    49921 gactggttgc cacaactaat ttcccttttt gtttgatagc atccacagca gactgagaac
    49981 cattagaacc tgactggcaa gctactaaga agaaacttgc aagaaaatta cataaaacaa
    50041 atatccattt ttttgatttc ataaataaac aacctctctg ttaattttgt ataattataa
    50101 cgatatccaa gttacttgtc aagtgttttt taaattttta tctcaaaaat attttttcgt
    50161 tcaaaaaaag gagccatcag ttgatttcaa gctccttttt atacagaatt aaactatttt
    50221 atagttcgac aatcttacct gtttcaaagt agacaaccca ttcacagata tttttagcat
    50281 agtcaccgat acgctccaag taggaaataa cttggaaata atcacgaccc gtaacaatgg
    50341 cttctggatt tttcttaatc tcttcagtcg caaggtcacg gatagtttca aaatagtggt
    50401 taatttgctc atccatggag gccacccggt atgcgtcgtc aacagaacca ttaagataaa
    50461 gatcaagtgc tgcttcaaca acgcttttaa cttcacgtcc cattttttta atttcttcct
    50521 ctacagctgg aatgcgttct tcccccttca tacggatggt tgcctgggca atggctacag
    50581 cgtgatcccc catacgctcc acatctgata cagccttaag gacagtcaag actgtacgca
    50641 aatcttgaga gactggttgt tggagtgcga tcatttcaaa tgatttcttt tccagtttca
    50701 cttcgtattc atttacttct gcatcatctt ctatgacctc ttttgccagg tcacggtcat
    50761 gcgtgacaaa agcacgtacc gtacgattga tttgtgagag cacttcttgt cccatagcgt
    50821 agaactggtt atgtaatttc tctaaatctt cttcaaattg agatcgtaac atctttcatc
    50881 tccttatcca aattttcctg taatatagtc ttccgtttcc ttgtgttggg gattaaggaa
    50941 catctgcttg gtatcattaa attcaatcaa atctccatct aggaaaaatc ctgtcctatc
    51001 agagatacgt gaagcttgct gcatggaacg ggttaccaga agcatggtgt acttgtcttt
    51061 tagaccatac aaggtttcct caattttacc agctgaaatc ggatccaaag ccgaagttgg
    51121 ctcatccaag aggatgattt taggactagt tgccaagaca cgggccacgc agacacgctg
    51181 ctgttgacca cctgacaatc caatagctga atcatataga cgatccttga cctcatccca
    51241 gatagaggca ccttgcaagg ctttttctac ggcttcatcc agaacctgct tatccttaat
    51301 tccattgata cgaagcccgt agacaacatt ctcatagata gtcataggga aaggattagg
    51361 ttgttggaaa accattccga tttccttacg taattcaacc gtatctgtac gcggactgta
    51421 gatgttgtga ccattgtaca ccacggatcc agttgtggtc acctctggat tgagatctcc
    51481 catgcggttg agagacttga ggagggttga cttccctgat ccagatggac caatcaaggc
    51541 tgtaatttcc ttaggttgga aagataggga aacactattc aaagccttct ttttattata
    51601 ataaacggac aggtctgata cctgtaaaat cgcatctgtc atacggtttc ctttctaacc
    51661 aaagtgacca gatacatagt cattggtgga ctgtagcttg gcattttgga aaatagttgc
    51721 agtcttgtca tactcaatca aatcacccaa gtaaaagaag cctgtatagt cacttgcacg
    51781 agcagcctgc tgcatattat gcgttacaat gatgatggta aagtttttct tgagctcaaa
    51841 catggtctct tctagttgca tggtcgcaat cggatccaag gctgaggctg gctcatccat
    51901 taagaggata tctggcttaa cagagatggc acgagcgata cagagacgtt gttgctgacc
    51961 acctgataag gtcaaggctg acttgtggag atcgtcttta acctgatccc aaagggcagc
    52021 ctgacgaagg gaggtttcta cgatttcatc taggacttgc ttatccttaa ctccagcacg
    52081 ttcatgcgca aaggtaatat tacggtaaat tgacttagca aatggattgg gacgttgaaa
    52141 aaccattcca atgtgtttac gcatttcata aacgttgatt tctggacggt tgacatcaat
    52201 tccacgatag agaatctgcc cagttacttt agcaatatca atggtatcat tcatgcgatt
    52261 gagactgcgt aagtaggtag atttccccga tcccgacgga ccaatcaaag ctgtaatttt
    52321 atttctttca aattgcatat caatcccctt aatggattca tttttaccat agtaaacatg
    52381 gacatcctta gtagaaaggg ctactttttc ttcaggaaag gtaaggatat gcttctcatc
    52441 ccagttatat gttgacatgg cttctccttt aggcagcggt taatttcttg tgtagatagc
    52501 ttccgaactt acgagctcca aagttaaaaa tcaggataaa gatcaggagc acagcggcag
    52561 aacctgctga tacaatggtt ccatctggaa tagtgccttc actattgact ttccagatat
    52621 ggacagccaa ggtttctgct tgacggaaga tagagatggg gctagtcaca ctgaggatat
    52681 tccagttaga ccagtcaaga gctggcgccg attgccctgc tgtatagatc agagctgcag
    52741 cttcgccaaa gatacgacca gatgccaaga cgacacccgt tacaatacct ggaagcgctt
    52801 ctggaataac aacatgaacc actgtctccc agcgagaaat cccaagagcc agaccagcct
    52861 cacgttgggt atggtgaacg tgtttcaaac tatcctctac attacgcgtc atctgaggca
    52921 agttaaagac tgtcaaggcc aaggcacctg aaatgattga aaatccatac tcaaactgga
    52981 ctacaaagat caagtaacca aagagaccca ccaccactga tggtaaagag gacaagattt
    53041 caatacaagt ccgcacaaag ttggtaacag gacctttttt agcatattca gccaagtaaa
    53101 tcccagctcc catagaaaga ggtacagaaa taatcaaggt aatgaccaat aggaaaaagg
    53161 aattgtaaag ctgaatgcca atcccaccac ctgcttgaaa agcagaagac cttccagtca
    53221 agaaagacca agagatatgg ggcaagcccc gaaccaagat atagagaatc aaggaagcca
    53281 agattgtcac aatgatgcta gcaatcgtat agaggacagc tgttgcaagt ttatctaatt
    53341 tcttagcgcg cataattttt ctttcctctt tctttcgtaa tcaatttaat cacactgtta
    53401 aaaactaaac tcatcaagag cagtaccaag gccagtgacc agagaacatt attatttaca
    53461 gttcccatga cagtgttccc aattcccata gttaatatag aagttaaagt tgcagctggt
    53521 gtggtcaagg aagttgggat aacagctgag tttccgacaa ccatctggat agctagagcc
    53581 tcaccaaagg cacgcgccat cccaaagacc actgcagtga aaataccaga acgggccgcc
    53641 ttcaagatca cacgccagat agtctgccag cgagtggctc ccatagcgaa actggcttca
    53701 cgataataac gaggaaccgc acgcaagcta tccgttgtca taaaggttac ggtcggcaaa
    53761 atcatgacaa agaggacgga aatccctgac aaaatcccaa aaccagtccc accaaagaca
    53821 ctgcgaacaa agggaacgac gacttgcaag ccaataaatc cgtacactac tgaaggaatc
    53881 ccaaccagga gttcaatagc tggttgcaaa atcttcgccc cttttggtga tacttcggtc
    53941 ataaaaactg ctgcaccaat agcaaagggt gttgcgataa gggctgagag aatggtaacg
    54001 ataaaggaac ccaaaatcat aggaagggca ccaaattctt tactagaagg attccaaatt
    54061 cctcccaaaa gaaagtcaaa gatattcaca ccattgacaa agaaggtcga caagcctttt
    54121 tgcgctacga aaaccaaaat catggccaca aggatgacta tcaaagaaag acaggcaaag
    54181 gtcaaacctt ttcctaattt ctccagacga gaattctttg atggaagcaa cattttctta
    54241 gctaattctt cttgattcat tattgtctcc cttccaacac tgtcacagtt ccggcagcat
    54301 ctttttcaac cttcatttcc ttaatcggaa tatacttcaa tcctttgaca atcccttctt
    54361 gggtctcatc cgagagaaca aaattgagaa attctgcagc caactcattg ggctgcccca
    54421 atgtatacat atgctcataa gaccacaagg gccaattatt gctacttata ttttctggac
    54481 ttaagtcata gccattcaac ttcatgcttt tgaccgaatc atctatatag gtaagagata
    54541 aataagagat agctcctgga ctttttgata cgattgattt taccgctcca tttgaatcct
    54601 gctcctgact ttgcatggca gactgacctt ccataatgac agtatcaaag gtagcacgag
    54661 agccagagcc ggctgcccga ttgataacag agatgggtaa gtccttacca ccaacctctt
    54721 tccaattggt tacctcacct atgaagattt gacgaagttg ctctgtcgtt aggttatcaa
    54781 catcaacctc cttattgaca atcagagcca agccagctac cgcgaccttg tggtcaacaa
    54841 gagcagaagc atcaattccg tctttttcct cagcaaatac atctgagttt cctatatcaa
    54901 ctgccccaga ctgaacctgg gacaagcctg taccagaacc tcccccttgg acattgaccg
    54961 tttttccaac atggatcgtg ccaaattcat ctgccgctac ttcaaccaag ggttgcaagg
    55021 cagttgagcc aacagccgtt atggattctc cacgatcaat ccagctagca cagcctacta
    55081 aacaagccgt cagccaaaaa gcgataagag acagagcaag cttttttctt tttttcactg
    55141 tttttctcct cgaaaataat tatgaatact gtgaattttt taagtagttc tttatgagtt
    55201 gacgcatgaa ttcttaccaa atttctgcgc aattgattat ttatataata taggctatat
    55261 tactctttcc taacctcctt ttttcatatg tggataaaat ctcttgtcta tcccttcccc
    55321 cattgtcacc cattatagtc atttcgtgtc tctttttccc ctttttaatg caagggaaat
    55381 tactcttctt agatgataat ccaaaagcta gaaaggtatc tcaaacctct ctactctccc
    55441 agactagttt acaactaaaa ggaaaagatt ctattttatg agaaatctag tttacaagcg
    55501 gtaagaacgc taataactaa acttcttgta ctctttgaaa atctcttcaa agcagtgttt
    55561 tgagctatct atggctagct tcctagtttg ctctttgatt ttcatcgagt agtaaaacta
    55621 catgtgatgg caatcaagat atcaagaatc atcctactaa aaaaatccat actttcacta
    55681 taacatagaa taagatattt gactagcatt ttcatttgaa tctgaggcct tttggaaaat
    55741 aatttttcaa aacatttcca gtaacctttg caaagcccaa gccattgcct ttaaccaaaa
    55801 cttggtacca accatttggc agactttctg ccagctgaac ggtttctcca gccgcatact
    55861 tgacaaacgc ttcttggcca atttcaaccg actgttcgac ctgactcggt ttcaaggcta
    55921 aaccaagagc gaaactgggc tcaaagcgtt tcttcttaaa agtacccaga tgcagtccat
    55981 tgcgagcaat cttgagcttc cctaaatctg gcaaaagttc tggcaagaga taaagctggt
    56041 ctccaaaaat ctgcaagata cccggtagat tgaccttcaa atggttttgg gcaaattcct
    56101 gccacaaggc aacttgttca cggctgaggt tactcttact tgccttaaat ttaggagctg
    56161 gattgttacc cttaaactgt agatgggcaa caaactgacc ctctccctta aactgatgag
    56221 ggtacatccg agccgtttct ggcaggtcaa taccagctac cattccattg atatgctcta
    56281 ctggcaacaa gtcaaaatca tactcttcca gcaaccaatt gacaatctct tcgttttcct
    56341 cgggtgccca ggtacaggtc gaataaacca gacgaccacc ttcagctaac atggtcactg
    56401 catcctccag aatttctctt tgcaagctag cacattgact cggataatct aagctccaat
    56461 agtccatagc atcaggttgc ttacgaaaca ttccttcacc agagcaaggg gcatcaagaa
    56521 cgattaagtc aaaatagcct ttaaagacct tgaccaagcg gtcggcagat tcattggtca
    56581 ccacgacatt tgtcgctcca aaacgctcca tgttttcaac caaaatctta gcccgtttgc
    56641 ttgaaatttc attggaaaca agtagcccct cccctgctag ataggctgcc agttgagttg
    56701 atttgccccc cggtgcagca gccaagtcca agaccttcat accaggactg ggttgggcta
    56761 cttgagccac catttgagca gcaggttctt gcgaataaac taaacctgta gcatgctcag
    56821 gcgatttccc tgaaaccttc ccatagtggc cccaaggggt ttgagtaatg gcatcagaaa
    56881 aggaaagttg ctcttctttt aagggattga cccgaaaggc cgaaaccgct tcctcctcaa
    56941 aagaggcaag aaaatctctt gcctcatctc ctagtatttc tttatatttt tcaacaaatc
    57001 cttctggaaa tttcatttaa gttcttttcc tttcgtaaat ataggactga atttcctcct
    57061 gcatctcaag aggcaccatc atgaccggct gtctggtttg aaaatcagga gcttcaccaa
    57121 aaagggtcac aacccgatag cccagacttt cccctaaaat actagctgcg gcataatccc
    57181 atggttgcag ataggtgaga taggtcaaca aatgccctga caaaatcttg gcaaaactaa
    57241 tggccgcact tccatagaca cgaacaccaa gaaccgctcg gctcaaatca gccagccccc
    57301 attcattggt ttccagcata ccactattcc ctgcaatgag aaaatctcca agtggtttag
    57361 ttttaaaagg agctaggggc ctatcattta gacaaactgg aaattcccca ccaccgtggt
    57421 aacaatcccc tttgaccaca tcataaatca gaccaaactg tccctgacca ttttcaaaat
    57481 aagccatcat aacagcaaaa tcttcctgct gggctacaaa attattggta ccatcaatgg
    57541 gatcaatgac ccaaaccttg ccctcttgaa ccgaggctcg cagacaacct tcttcagcac
    57601 aaatcttatc ctcaggataa cgggacaaaa tctcaccaac caagagttcc tgaacttctt
    57661 tgtccagtct ggtcaccaaa tctgttggag aggacttggt ttcaacacgc aagtcttcct
    57721 gcatatggtc aagaatgtac tggcctgctt tcttaacaag ctctttagca aattcaaatt
    57781 tactttccaa gagaaatctt tccttcccct ttttctttgg cagcctgaac tgctcggtaa
    57841 agtgaatagc cactaaccgt ttcaaattct cgtcccaaac gtttctcttc gctcttgctt
    57901 ggcacgacct ctttgaatcc cttataggag tccagtaact ttttagcctc tactttgctt
    57961 tcataggcag cttcaacatc attaaaaaaa gaaagcactg aagcaagttc ttcagtgctc
    58021 cacgacaaat ctagtgggta actatactgt ttgttcatta actaatacca gctctcattc
    58081 ttgcttcttt tagttcttgc ttacgataac tacgagggag aaaagcacga atctcatctt
    58141 cattaaaacc gatttgcata cgcttggcat caataataat tggacgacgc aaaagactag
    58201 gatactgctc aatcaaatga agcaattccg ataccgaaat actctctaca tcaatattca
    58261 atttttgaaa aatttttgaa cgagttgaaa tgatgtcatc agtaccattt tcggtcaagg
    58321 aaaggatgtg ttgcaattct tttcttgtta aaggactggt cataatattg tgttccacaa
    58381 agggaacctt atgtttttct aaccaggcct tagccttacg acatgatgta cagctcggtg
    58441 atagaaatag tgtaatcatg cttttctctt cttatctata ctttgctact tctattatac
    58501 aaaaaaataa agcgcttgac tagggatttt tagaaaaaaa gcctattttt tcaagaaaaa
    58561 taggcttttt gcgaacgatt gacacaattg gatttggtta attcactctt aacgatggtt
    58621 ttaaacgata tatattttta tatatgtaaa ttaaaaacat ctttcctttc acttcctacg
    58681 acttttcaga tacagatagc caaagaagtt ttcatagagg gcaaaaaaga ggaggaaggc
    58741 atgaagaaag aaggtctctg gcaaaatcat aataacagga tccttggctg gatcaaaaag
    58801 ccaggtatca tctcccacaa agagaatttg atggaaaaga gtaaagaatt ggtcaaaacc
    58861 aatcaaaact cccccaagtc caatcatcac aggtaagact actagagcca ggagactttt
    58921 tcgataaaga gacaaaaagt cctttttcac aatcctattg acaaagacat agaaacttgg
    58981 cagtgtcact agagctacta gctgaaccaa atgaaagaga ttcttgacca ctgcgaaatg
    59041 gtgcagacca gctgctgacg aacgaaaatc aggcatctgt aagacctgac taaaaggatt
    59101 ggtcagataa ttcatcaaga tatgaaaatt gtattgaatg gtttctggtt ttagatagac
    59161 tcgattcgtt aagtttagcc actgaatctc cataggatag aaaatccaag ccagataaat
    59221 ggtcagaagg attgagaggg agaggagaaa gagcatagag ccccaaaagg tcaatttagt
    59281 tttcatcaaa atcccactcc gcaaggctag aaaccacatg tgtcggtgcg attggcaggc
    59341 cagctacttc ttctgcctta gtaaaacctg tcgtcaccaa gagcgttgga atgccattgt
    59401 caatcccagc ccggatatca gtcaaataat tgtccccaac catgattaac tcttcacgtt
    59461 ccaaacctaa gtgctcaacc gccttgtcca taatgatggc atttggtttt ccgatataaa
    59521 ccggcttcac tcgtgtcgct acttcaagca gcgtaatcag tgagccagca cctggcaaaa
    59581 gaccacgttc cgtcgggatg ttgaggtcag gattggttcc gataaaatgg gcaccctttt
    59641 gaatagcaag agttgctgtg gcaaattttt catagtcgac ttgccaatcc agaccaacta
    59701 ccacgtaggc agggttttcc ttgtcttcca cataaccagc cgccttgatg gcttccttga
    59761 gtcctgcttc tccgacgaca tagacagtct tttcaagccc caaatcattc atatagtcga
    59821 tggttgccaa agtcgctgtg tagacagtcg atagaggcgt atcgatatta aaattctgag
    59881 ccaacatctc cttaacactc tctggagtgc gggttgtatt gttggttaca aagagatagg
    59941 gaatgtcccg cttttgcaat tcatgaacaa aagtctctcc agcagggatt cggtctttcc
    60001 ccttataaat ggttccgtct aaatcaatta aatagccttt atatttcatc tatttctccc
    60061 taaacctttt ttatttcttg ccaagtaatg attgcttggg cattgataac cccatcactt
    60121 gtaatttcat gcttgctttc cagtccagtc cgttcaacag ccgatgtaat caccccacct
    60181 ggtcgaactt ccttgacata cttgaggttg attttcttgg gaatatagtg ggtcaaaaaa
    60241 tccgctccca tgacctcaaa aatccagtcc aagtatttac tgttattgac atgaccattc
    60301 atatccaagt cgtaaaaacg aacatggtaa tccttgctga tcggctcttc caaggattca
    60361 tacttcggtc cacggataag ttttttatca aaatcagact ggtaaggagc cacaatctca
    60421 ggttcaacag catggacttt tcgactgtcg cggtccatga gaacaaaggt cgccatcata
    60481 tggatgagct cctgccccgc ttcattataa atagtaaagc gacggtagca aaaaagtcga
    60541 ttgtagctca aggcttccgt ttcgatggta atttcttccg caaaacgagg caaacgaacc
    60601 acctcaatat catattctgc gataatccag accagattat agtcttccaa aatggcctta
    60661 tcactaactc ccagttcaat cgattgcatc cctgaaactt gcagtgacag caaaatcaca
    60721 tctggaagtt tgatatgacc gttcatatca gccatatcaa aaggaatttt cattttcatt
    60781 tgataagtta agcacatgat cctactccaa aataaatcgt tctgctacag tatctcccaa
    60841 aaagagacct ctctttgtca tgcgaacgtg gtcaccctca atctgcatga ggccttgttg
    60901 aaccaaatct ctgacaattt ctccataaag tccagcaaaa gactgtccaa atttttcctc
    60961 aaatcgcgcc atggaaaccc cggatttctt gcggagtccc aagaacattt cttcttccat
    61021 ttgctccttt tgactcaggt gatcttctgt aatacaagca ttgccttcct caaccgcact
    61081 gagataatga cgaatgggac catgattttt atagcgtact ccattgacat aaccagatgc
    61141 ccctgcacca ataccatagt attcagcatt gtcccagtac atgagattgt gacgactttc
    61201 aaagccgggt ttggagaaat tagaaatctc ataatgctca aaacccgctc gctccagctc
    61261 tgcaatgatg tactcaaaca tctccgcttc tagttcctcc ttaggcagag gcaatttccc
    61321 acgtcgcatc cggttcataa agaccgtatg gttttctaaa atcaaactat acaaactcat
    61381 gtggggaata tccagtccaa tggctttagc cacattttcc tttacttgct ccatggtctg
    61441 accaggcaga gcataaatca aatcaatgga gatgttgtca aaaccagcca gtttcaggcg
    61501 atcgatattt tcataaatat ccttctccaa atgactgcgc ccaatctttt tcaacatctt
    61561 atcatcaaag gtctggacac ctagcgaaac acgattgaca gccgaatttt tcaaaacagc
    61621 tatcttatcc gcatccaaat cgcctggatt ggcttcaatg gtcaactctt ccaagacaga
    61681 caagtccaag tttttagtca agccattcag taacacctcc agttgcggag ccgacagggc
    61741 tgtcggtgtt ccaccaccga tataaagggt tgacaacttt tcaatatcat aagaacgaaa
    61801 ctcttccagc agatgctcta aatagctgtc gactggctga tttttgatga agacctttga
    61861 aaaatcacaa taataacaaa tctgggtaca aaatgggatg tgcacatagg ctgacgttgg
    61921 ttttttctgc atagtaatta ttataccaca aagactagat tccagataaa aatcaccatc
    61981 cccagataca tagtccgtcc ggagatggtg atggtttatt cttctgttat atcaatcaca
    62041 atctcttctg agtcatcaag agcttcggct ttttcttgcc attgctcctt gagattattt
    62101 aattgatttt ttgatgcttc tgtcgcttga aaagcatagg atttagcttg agcaagtata
    62161 ctgtccacag tgatttcacc tgactcaacc tgttcttttg ttttcagaac aaaatctgta
    62221 gcctgctcct taacttctgt cagtttttca cagacttgct ccttggcata ctccggatct
    62281 tctctcaaat catctagaaa atcttgagcc tgactgcaaa cttgtttgcc cttatcactt
    62341 gttaaaaaca aggcaagagc tgcacctgaa acggttccta aaaggattga ggataattta
    62401 cccataagga ttctcctttt ttattttttg aaaaatttac ttgcaagacg aagagctgac
    62461 agacttgcac cagtcttgag tgtttttgaa ccagctgatg aagctttctt gctcaagaca
    62521 cgcgcatggt cattgaggtc tgaaacagat agagataaat ctgcaacagc actgaagagt
    62581 ggatcaatcg tagccacctt gacattgata tcatctgcca agacattgac cttagccaac
    62641 aactcattgg tgtgatgcaa ggtcacatcc acatctgaag tcaaggtttt aatcgtcttt
    62701 tctgtttcat cgatgacacg accaagcttt tgtacagtaa tgatcagata gaccaaaaag
    62761 acaatcaaag ctagggcaac aagaatatat gcaacttcta acatttagtt ttcctcctct
    62821 gtaatatagt aaggggcctt ctttcgattt tgataaataa cgatcattat accgagaccg
    62881 ataaagacaa ctgacagcca ttgggacact cgaaggctga agaacatgag actatctgtt
    62941 cgcatacctt cgatgaccat acgaccgaaa ccataccaaa tcaagtaaaa ggccgtgata
    63001 tgacctcgtc tgagactctt ccatttccgt ctaaaaatca gaatcaaggc aaagccaagc
    63061 agattccata gagactcata aaggaaagtc ggttgacggt agctcccctc aatatacatc
    63121 tggtcacgga taaagccagg tagataatcc agattatcca ctgttgcacc ataagcttct
    63181 tggttaaaga aattacccca acgccccaaa ctttgagcaa tcataacgct aggcgccgca
    63241 atatctagaa aatcccaagt attgatgagt ttacggtcag caaagatata gagcacaaga
    63301 gccccagtta tcaaaccacc gtaaatggcc aaaccaccat tccaaatggc aaaaatctct
    63361 cctaaattct gactatagta atcaaatcgg aaaataacat agtagagacg agctcctaaa
    63421 atagccaagg gaaaggctac taagataaaa tctaaaatat cgtctggtat gatcttcttt
    63481 ctaggtgctt ctttcatggt caaataaacc gcaagaatca agcctgtcac aatacataag
    63541 gcataccaac gaatggctag gggtcctagt tgaatagcaa ttggatcaag cattttgcac
    63601 ctcatttcga gctatgagac ttgtcagtcg ttcgtcgaac aaacgggtag catcaaagcc
    63661 catttccttg gcacgataat tcatggcagc tgcctcaatc acaacagaga tattacgacc
    63721 tgttttaact ggaatacgaa tacgaggaat ggctacgcca gaaacttcaa gttcctctgc
    63781 attgtttcca agacgatcaa aggtcttatg cgtatcgtaa ttttccaaat agacagcaag
    63841 ctgaacctgt gaagaatcct tgacagcact cgcaccgtag agactcataa catcgataat
    63901 accaacccca cgaatttcaa tcaagtgttt caaaatttca gctggttcac cccagagagt
    63961 aatctcatcc ttggcaaaga tatcgacacg gtcatcggct accaaacggt gaccacgttt
    64021 gacaagctca agacctgtct cgctcttacc aattccacta tctccctgaa tcaagacgcc
    64081 catcccataa atatccatca agacaccgtg cacactggta cgttctgcca aacgagaatc
    64141 cagatagcta gataactctc cagataaacg actggtagct gcacggctgg ttaaaatagc
    64201 aatcttacat tctctagcag cctttaacat ctcctctgga accaccaaac cacgggcaac
    64261 aatgactgct ggtgtctcag gtagaaacat ttttttcaaa acttcataac ggctgttgga
    64321 aggcatgctg atcagataag accactcctt catccccaaa agttgaatcc gctctggtgt
    64381 atagtagtca aaatagcctg tcatttcaag accaggtcgc gtaatatccg ctgtattgat
    64441 ttccttttca agcaattctg gttcaccata gacaatatct agtctaagct tttcaatcac
    64501 ttcttttact aaaaccgaca tcatttcctc cttcaaatga attcttctct ctattatatc
    64561 aaattgtagg aggaagtttc agatttttgc aggctttgga gtatttattt aaaagaaaaa
    64621 ggactagatt tctctagcct ttcatttcaa ttagaatttt ttacgtttac gagctacttc
    64681 tgatttacgt ttacgtttta cagaaggttt ttcatagaat tcacgtttgc gtgtttcttg
    64741 aagagtacca gctttagtaa ccgcacgttt gaaacggcga agtgcgtcgt caagagattc
    64801 attcttacgt actactgttt tagacatttt tttcactccc ttcaagttca atatctattt
    64861 cattctacac gtaaaaggaa taattgtcaa gcaaaaatgc ggtttaattt tgattttttc
    64921 ttccatttat acaagagttg aaagcgttca atagaacatt gcttttttat ttttcgagta
    64981 agctaagcgc ttcagcatct gcgatgatgg ttacatcagg gtgattttgg aggctacttg
    65041 caggtaggtt ctcagtcact gggccagata ctgttccggc aatggcttct gctttcgact
    65101 caccataagc aaaaagaata atagacttgg catccaaaat gtttttaatc cccattgaaa
    65161 tagcttgggt tgggacgtct tcaatcttgg caaagaagcg agcattggct tcgatagtag
    65221 actggtcaag ttctactaga tgcgtttgac tgtcaaatgg agtaccaggc tcattaaagc
    65281 cgatatgccc attgcgaccg attcccaaga tttggaggtc aactggatgg tcagccaaaa
    65341 tttggttgta gcgttcaact tcagcttcag cattgtcctt aacaccacga ggcaagaaac
    65401 tttctttaaa tggtttttgg ttgaacaagt tttcttgcat gaagtaacga taagactgtg
    65461 gattgtcccc atcaaggccc acatactcat caaggttgac actggttaga tttgaaaaat
    65521 caaggtcact ctcaacaatt tccttgtaaa attcaagtgg gctacttcct gtcgcaagtc
    65581 ctagagtttg agctccatta gccaattttt ccttcaaaat ctcaaaagca acttttccac
    65641 cttgaacttg gttttcaact ttaataactt tcatcttttc atcctccatt tctgtctata
    65701 tttattatat ggtatagacc aatttttgtc aagtgaaaac gatttaattt ctaaaaaaag
    65761 agcgtccaaa cttgaaacgt gttataatgg ataggattag aacttagaaa gaatgaacaa
    65821 atatatgaat acagctgatt ttgatttcca cttgccagag gaattgattg cccaaacgcc
    65881 ccttgaaaaa cgtgatgcct ccaaactcct catcgtcaac cgtgagacag gagaaatgca
    65941 agataaacat ttccactcta ttattgatat gctggaacct ggtgatgccc ttgtcatgaa
    66001 cgacacccga gttctccctg cccgcctcta tggtcaaaaa gtggagacag gaggtcatgt
    66061 ggaacttctc ctccttaaga acactagtgg agacgagtgg gaagttctgg ctaaacctgc
    66121 caaacgcctc aaggtcggta ctcgtatcag ctttggtgat ggccgcctca gcgctgtcgt
    66181 tacagaagaa ttgacccacg ggggacgcat tgtccgcttt gaataccaag gaattttcct
    66241 agaagtcttg gaaagtctgg gagaaatgcc tctgccacct tatatccacg aaaaattaga
    66301 tgaccgtgaa cgttatcaaa ccgtctacgc caaggaaagc ggctctgctg cagcaccgac
    66361 tgctggtctt cacttcacca aagaactgct ggcagaaatc caagctaagg gtgttcatct
    66421 agtctatctg actctccatg tcggactcgg aacctttaga cctgtttctg tggataatct
    66481 ggacgaacac gaaatgcact cagagttcta tcaactttct gaggaagctg ctgccaccct
    66541 tcgctctgtc aaagaaaatg gtggtcgcgt catcgctgtc ggaaccactt ctatccgcac
    66601 cttggaaact attggttcca agtttgatgg gcaaatccaa gcagattctg gttggaccaa
    66661 tatctttatc aaacctgggt atgagtggaa gatcgtggat gccttctcaa ccaacttcca
    66721 tctgccaaaa tcaactctgg tcatgttggt ttctgccttt gcaggccgtg aattagtctt
    66781 agatgcctac caccatgcca tccaagaaca ctaccgcttc ttcagttttg gtgacgccat
    66841 gtttatttat tgagaaagaa tttctctaat tcttctaata ccaataaatc gctaagatat
    66901 tatttcaaag aacatctaca attgaaactc tagctagctg tagaagacgc ctagtacatt
    66961 gaaattaaaa tgcttccccc tagcttcgaa aatattgcca tagattgcgt tgactctcca
    67021 aattgattca tctatatttt atttcagctt cctatatttt cttcgctgtt tgtaaatcaa
    67081 aatgcaagac acatgagtag caccatattt gttactctta tctgtcctct caagagacta
    67141 ttatgagtta tttcagaatc attcactact ttgaccctga ctctccttag tctcaaaatc
    67201 aaagacttat actctccaaa aatctcttca aaccgcgtca acgtcacctt ggattatata
    67261 ttcgtcagtt ctatctacaa cctcaaagca gtactttgag caacctgcga ctagttttct
    67321 agtttgctct ttgattttca ttgagtatta aacaaaaagt gaacaaatct gaattctaat
    67381 gtacagaaga ctaggcttgt tcactttttt atagtcgcta taagatgacc ttatctatag
    67441 ctttttatat ataattatat attcagacat actattatca attttgtcgc agggaggaat
    67501 ctgttaacgc acccattcac cattatcatt gactctatag ccatctatac ttgtattgac
    67561 cgctaactca cccgatgcat ttacataata ccatttacca ccaacttgga accattgatt
    67621 gactttcata gaaccgttgc tgttgaggta gtaccatgaa ccattaactt gtacccaacc
    67681 tgttgccatg gaaccatcag tattataaaa ataccacata ccattttctt gtttccagtc
    67741 tgttgttgga gcaactgctt tagctggttc tactgctaca tctgttcctt ggttagatgt
    67801 aacagataca ggatacgaag gaatagatga ttgctcagga acaacaactt tttcaggttc
    67861 tctcgtccct ctccttatac gtctttttac catctcttta gtaatttgac gagaagtagt
    67921 ttcttcaatt attccatcac gttcatctac agtatagatt gtagtaagag taatttacca
    67981 atttctccta cttcttctac ttcttgactt ttatcaagag ttgggccatc gagatattct
    68041 gtttcgattg gaatttcttg gacaagaact tggggcttgg ttcctttttt aacaactctt
    68101 gtttgagagt ctttttttga cttaaagtac tctcagttac ttgtccactc tttccatcta
    68161 cattataagt tatcgttgta actgttttcc cattctttcc tagagtaatc tcttgctcct
    68221 gtcctgcaga aaggtcattg tctgcttcat atttagtagc aaatggaaca agaacttctt
    68281 caatcttgct tttagctgga actttgataa ctgtatccgt ggcttctttt ctatcaacag
    68341 taacctgttc ggtaacataa ccagtctctg gattaacatc gtaggtcctt gtcgtagtta
    68401 catagccatc ctctccgtca attgtaacag gattttcact acggtctttt gtttcatctt
    68461 tttcaaaacg aattcgcgta cttgaaattt tcttggttac taccttaggt ttagtcgcta
    68521 cttttacaat aatatcccca ttgtcagcgt catcatactc tattccctct tctttatctc
    68581 tagtatcatc tctgacatat tgaatcccat cagcagcatg agcaaaactt gtattcagat
    68641 tcctcctaaa aataaagtta gcccgattat cgcagaacca aaaatctttc cgagtttacg
    68701 tattgcataa cgcttattag tattagattt tgccattaca tcctacttct agtatagcat
    68761 cttttctatc aaacgttaaa caatatactt tatatataaa atagacttag aatgatatat
    68821 tgattattga actaacactt taactatatc gtaatcaatc tcatatataa aggattgcag
    68881 acatctgatc taaatacatg ctaatatatt tagatacaaa cattccaact tgataatttt
    68941 cactcatctt tcaacattcc ttacacaacg atgcagtata aatagaatag ttttctcatc
    69001 agaatgagac tattttaata ttagataatt tgatagaaaa aaacataaat aaaattggtt
    69061 gaatttaatt ccctaactcg atagaggatt ctattttaaa tttaacaaca gctaggatta
    69121 cactataaaa agtacattac cacctgttcg gctggagaat ctagtcgatt agctccctct
    69181 tagttacaag cttaaagcga ttttttaact aatactaaac cagattaaag aaggaactag
    69241 aacatctgtc ttgtactaat caatatgcta ttttaaaatt gcaaataaac ttggaatgct
    69301 aattattata tttacaataa atagttgact tcgatagaaa cagaaaatag aattcaacat
    69361 tcttccctac ttataccata ataaataaga tccgcaagat agccttttct ctctacacca
    69421 ttaacaatgg tttgtagata ggacattcca gccttttcca tgacacgacc tgaagctggg
    69481 ttgagactgg cataacgtgc tctgaccttt tgaaaacctg cttgagtaaa acaaaagtcc
    69541 aagacagctt tcaaggcctc tgtcatcata ccatgtcccc agtaagcctt gcctagcaca
    69601 tagccgattt cacagcttaa atcagcctcg tctatcttaa cgatgctgat atctcctatc
    69661 acttgctctg ggttttcttt tagacaaatg gcccatttgt aatagttgag attagtatag
    69721 gaagcaaccc aattgcgaat cgagtttcga gtgatttcga catcaggatg gggatcccag
    69781 gtaacatagg tcagattctc agtggatgaa gcccaatttt gaaacatggc ttctgcatca
    69841 ctctccacaa atcttcttaa aatcaaacgt tctgtctgta atatttgcgt accgatagat
    69901 ttcatgatgc tacctcactt ccttatttct atactcgtag taaaaaggct caactcagta
    69961 acagctagaa aacgagtttg tcttctaatt tcttgacgca gttgctgcct ggtttgaaat
    70021 gcgctctagc aagctttttc aaacctagtc atcgttgcag gggtaagacg atgaaatcga
    70081 actcttcgag ttactgaatc tgcctcattt tcttatttct aaactcgggg ttcaagatcc
    70141 cccagacctt ctctcacttt cttatttcaa gatgagaggc tgaaaacctc cagtggaggt
    70201 ttttcttgct ttttaatttc agggcaagaa gctaaaaagg tcccccgaac ctttttactc
    70261 ccaaaagtca tcaaatacgg tgatgggtaa gtggcgtttg tgttggcctt tgtgccacca
    70321 gttttcaatg gtcgcttgag cttctgggct gattgttttg ccttctaggt agtcgtcaat
    70381 ctctgcgtag gtgactccaa gtgcgacttc gtcagctagg cctggtttat cttcttctag
    70441 gtctgccgtt gggatttttt cataaagggc tggctctgcg ccaagtttct gcaagagctg
    70501 ttttccttgg cgtttattga ggcggtaaag agggagaata tccgcaccgc cgtcaccaaa
    70561 cttggtaaag aaacctgtga tattttccgc ggcgtggtct gttccaatga ccgctccgct
    70621 atgggaacca gcaagggcat actgagcaat catacggcaa cgtgccttga tattcccctt
    70681 gttgaagtct gaaacaggac tacctgtcgc ttcaactgca gctgtcatgg catcagctga
    70741 ttccttgata ttcacaacca agctgacatc tggctggatg aaggctaggg ctttttgagc
    70801 atctgcttca tcagcttgca ctccgtatgg caggcggaca gcgataaatt tgtagctatc
    70861 gtctcccgtt tcagctcgca gttcttccat agctaattgc gccaaacgtc ctgccaaggt
    70921 tgagtcttgt cccccagaaa tccctagtac aaaggttttt aggaagggat gttttttcag
    70981 atatcttttt aagaaatcaa tagaacgacg gatttcttcc tgggcatcaa tcactggttt
    71041 gacacccagc tcttggataa tcgtttcttg caaactcatt cttcttctcc ttcaccaagg
    71101 gcttccttgc gcatcttatc aatcaagtcc atcttatctt gccatacatc acgcgccaaa
    71161 tccactggat agtgctgcgg attgagcaca cgcttatact catcccacaa cttgtcaaat
    71221 tccttacggg cataatcctg aatgtcagtc aaactaggca agttgtaaac taatattcct
    71281 tctttgaaga tatccaccaa gagaggaacg gcatcaaaat tacgaaccgt cttcttgatg
    71341 tatgtatagg tcggatggaa catcttaatt tctgtcatgt cgctaatatc cacaccatca
    71401 taagtgatgt agtcaccttc tgacttgcct ttttcacgac tggtaatgcg ccacacctgc
    71461 ttcttacctg gcgtcgacac tttttccgca ttattagaca gcttaatcgt attgcgcatc
    71521 tggccgtttt catcttcgat tgcaacaatc ttgtaaaccg ccccaagagc cggctggtca
    71581 taggctgtaa tcagcttggt acccacaccc cagacatcaa tcttggcctt ttgcatcttg
    71641 aggttaagga tggtattttc atctagatca ttagaagcat aaatcttagc ctctggaaat
    71701 ccagcctcgt ccagttgctg acggactttc ttagaaatgt aggcaatatc cccagagtca
    71761 atccgcacac ccataaagtt aatctgatca cccagctcac gcgccacctg aatggcagct
    71821 ggtacaccga tgcgaagggt atcataggta tccacaagaa agacacaatt tttgtgggtc
    71881 gcagcgtaag ccttgaaagc ctcatagtca ttgccataaa cctgtaccaa ggcatgggca
    71941 tgggttccca aaacaggaat gtcaaagagc ttacccgcac gcacgttgct ggttccattg
    72001 gcgccaccaa tcaccgctgc gcgtgttccc cagatggccg catccatttc ttgagcccga
    72061 cgtgtcccaa actccatcaa gggttcatct tcgataaccg aacgaatacg agctgccttc
    72121 gtcgccacca aggtctggta gttgacgatg ttcaaaagag ccgtttcgac caactgacat
    72181 tgggctagag gtccttccac ctgcacaatc ggttcattag caaaaaccaa atccccttct
    72241 tgggcagaac gaacggtcaa ctccaacttg aaattgcgaa ggtaatccaa gaacgcccca
    72301 tgataaccaa gcgactccaa ataggctata tcactatctg aaaaacgcaa gtcttcaaga
    72361 tagttcacaa ttctttccaa acctgcaaaa accgcatagc cgttcttaaa aggctgttgg
    72421 cggaaataca cctcaaagac cgccttctta ttgtaaatcc cttgatcaaa gtaaacctgc
    72481 atcatgttga tctggtacaa gtccgtgtgc aatgtcaaac tatcatctgg atacatactt
    72541 ttcctacttc cttagctaga aacccatgaa aattttcaag aactttcatg tattccaata
    72601 aattagtact attatatcac attttagctg gattgagaaa agagtaacaa gctattctcc
    72661 actctccaat tcatccatat cttgttcaaa ttttttctga gcccattcgc catagctctt
    72721 aagaccaaga ttgccaataa agacccacgg aaggtaaatg acataagtaa tgacccaagc
    72781 agacaggtat ttaaaattca aaggattgtg ctgataaatt tctatgttga attgataatt
    72841 ctgcaacatc aaaagagccg taatagccaa ggttaggaaa aaacaaccca aaatcgtaaa
    72901 atgaaaacga ctatagtagg tcactcccag ataacgggca cgattgaaaa agtaaaatgt
    72961 ccctatgatg ataacgatta gcagcatatt agaattaaaa aggcttggtg ctaatactga
    73021 aatgatataa gataggagcg acaaagcgat gcagatatag aaactttcag agcccgcttt
    73081 attgaacagt tgttcttctc tttcgtctag taattgataa taataaaatc tatttttcat
    73141 cttcttcctc ccaaaatagt tggtctaggg ttttccctaa acatctgcaa atggactggc
    73201 agagcgagag actgggattg tatttccccg cttctatcaa accaatagtc tggcgcgtca
    73261 ccccgacagc ctctgccagt tgaccttgtg ttaaatcacg ctctacccga gctaatttta
    73321 attttaaatt tttagccacc ttcgtcctcc ttatagtttt aatactcatc tactcttaaa
    73381 aaatccaaaa ccaacacaag ctatcagcta tttattataa ccccattaat ttgcactcca
    73441 gtattatctt cagccgaaaa tcagtatttt aggttgtttg aaataaactt cctagtttac
    73501 tcttttattt ttatttagta ttagctttag taggatcttt taaacgagtt tttattgctt
    73561 atatttcttg tttagtttag ttggtttcat atcactatta tataatgctt ttggaaatga
    73621 gcctagtata agtcaaaaac gtgttgaata gtgaaagtag gagcatacca agatgactga
    73681 tttttttatt gtattttagg tatgcaaaat aatactaaat gaaactaaaa tgaatacttc
    73741 ttgcttttct tgagagtgaa aaagtacaat aaaatgattg tagtgattac cacaagatac
    73801 tgactaatag acatcgtatt tgaagccaca aatacaggta aagaataaaa aggaagaagt
    73861 tcaattgctt tgataaacaa atcattacta gtattcatca tcatcgtatt taatatatta
    73921 gggataaaga gtagtaaagc tactaaaata ccaaatacca agccactttt caatttgtat
    73981 aaataaaaaa tgtaagataa tagaaaataa aacaggacta acaaaattgt attgactaca
    74041 atagctacta taaaatctaa tcctaaatca cctggaatac ccaatttact tactatgact
    74101 agtaacacaa tgccattcaa agcataaata atggaaactg agatggcata tagaaaatta
    74161 gacaagacgt aaatcatccg attcttctgt tgattataaa acaaacttac cgtattgtgg
    74221 gaaaaatctc tactaataac tcgattagca tgtataacag ccattaacat accgagcata
    74281 gcataaaagt ttgaaatatg cttaatacca agcgatgtcc cttgagtctt tagaataaag
    74341 aatgtaagca atatcggcgg tataaacgag ataagcaaac tgagatatat tacgcctgat
    74401 gaatataaat ttcttatatt ttccttaaga aaattcaatt tatttaattt catgattata
    74461 accttccttt attttgaacg atttagataa atatctttaa gcgtctcttt tttagtttca
    74521 aaatcaacta ctttaataga gttttcgtta aaaaatttaa aaagctcact actttgaata
    74581 ttcccagaca tagtaattct cagtccctct tcctgaacaa tatccccaaa ttcttgtttg
    74641 gtaatgaaaa tatctctatc tgtagctgat gaaaaagcta tctcaaacaa gaaattatga
    74701 ctatcttttc ctactttttg aaatgtcaaa agcccgttct ccaagaaaag aaccctctca
    74761 caaatttctt caatatcttc taatttatga ctcgatatta aaattcccac attttcatgt
    74821 aaagctaaat tttttagaac cgataaaact atttgtgatg attcaatatc taaaccatta
    74881 gtcggttcat ctaaaatcaa tatatcaggt tccgtaacga gagttagaag caaagctaat
    74941 ttttgttttg tacccaaaga ataggtcttt acttttttat taatagactg agtcaaatct
    75001 aactcttgga tcaaacttct aaatctttct tgattgtagt caacaccata taaatttgac
    75061 aaatatttta aattctctaa acctgtttta gataaaaata attttggttc ttcgattaaa
    75121 tacccaacat tatcactgct tataatatta cctgaagtcg gttgattatt ctgaacaaga
    75181 attttcatca acgtactctt accaactcca tttctcccta ctagaccaac aatttcaccc
    75241 ttgttaagtg caaaatttat atctttgaga atgattgaat gaccataatg cttacttaca
    75301 tttataactt acatttttta ttcctccatt aatattcatg gtttgctctt tgattcttat
    75361 tgagtttaaa aagttgcgcc tctttttaac aacattatat catatatcta acttaatgca
    75421 atatataaat gtcattttgt aaaattttat taacaaaaaa ctctctacaa caaaataata
    75481 gagagttttc tgcttattaa tttttttcaa aatatctaaa catcacttct ttgtttaatt
    75541 tgataggctt tgatacctaa gctccgactt tatcacttaa aaaataaaaa aggacagcta
    75601 atctcttgcg catcaaggga tttcgccatt ctttaatctc gtttaagtgt tgtatatgga
    75661 gctttgcatc attttttaaa actaaacagc tacattaagc acgaactgtg acgctggttc
    75721 catcttcctt ataaagattg atgagtcctt cttttaatgc acgaaccatg tctcctgatt
    75781 gaacgggttg aggcacctta atagtcaata gttccattgg atttggagcg cggtcgattt
    75841 tattgccttt ggcatcatgc aaatcttcaa tataggtttc aaaatgacgg aaacctggac
    75901 cataaaactc aacttggtcc ccttcgttaa tgacatttcg ttgacgaata gttgctgttt
    75961 gtgccgcatc atcataagaa accacttcag cgacaaactt gtactcagga attttacgac
    76021 gagcaccaaa caactgctca ttttcagatg gtgtaccata gtaaaatcct gtagccagtt
    76081 cacgttgggc aaccttccac atctcgtcca ccaagtcttg tttgatagct tcaaactttt
    76141 caggactttc aagataggca tccacagccg ccttgtagca gttggttact gttaatacat
    76201 agtgaataga ctccatacgt ccttcgattt ttagactgtc cacaccattt tcaatcatat
    76261 ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct tctggaatct
    76321 caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg tatttccaac
    76381 ggcatgactg agaacatcca ccacggttgg catcacgcat actcatgtgg tttgaaagag
    76441 tacaacgtcc agagtatgaa atacacatag ctccatggac aaaggcttca atttcaacat
    76501 ctgtacgttt gcggatctca gctaattctt ccattgaaac ctcacgcgct aaaacgacac
    76561 gagtcaagcc tagctctttc cagaactcaa gggtttcata gttagtggca ctggcttggg
    76621 tagaaaggtg gatttcaagg cctggtgctt cagtcgctgc aatcataatc aaggctgggt
    76681 cagatacgat aactgctgca atcccgatat cacgcagttt acggaaccac tcaccagcac
    76741 cagcttcatt tccttcgtgc ataaccatat tagccgctac atagaccttg gcaccatact
    76801 tggccgcaaa ctgcacgcct tcttccatct gttcgaaagt aaagtttccc gcacggctac
    76861 gaagaccata ggcctgacca ccgataaaga cagcatctgc tccatactga acagctacct
    76921 ttagcttctc taaagtccct gcaggtgata aaacctcagg acgttttaat gtttttgtca
    76981 tgatttctcc tatttgcaat ataaaagttt gacatttttc cttctcattt tatagtaaat
    77041 aaaggataaa atcaagccta gacggattgt tttgacaatt ctaatctttt agactttgca
    77101 taataactgt taaacagtcg aaaattaccc cagttttaac aagtagtcaa aaagtctaaa
    77161 aaagtaaaaa ccagtatccc aagatactga ctcgtaaaaa tacataaatt agtccttaga
    77221 tgactactcc cactctgttg ctcctataat ggaaaaggat tgatacagtc tagaatatcg
    77281 cttttttatt tattattctg atataaaact gttagaattg attttttgtt ttatacccaa
    77341 atatgaatag agacgtagct aataagttga ataacatatt tggaaaaatg agaaatagca
    77401 atattactag aacttttaga aacaatcaat atttaaaaag aaaaaagctc aaagaattta
    77461 ttaaaccatg ttataataga tatagctata attttattta taacaagagg atagaaatga
    77521 ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat attctgataa cttaaacatc
    77581 aaagttcaag agagagttcg tgaaatggca aatgataata agagccatta tttgatatac
    77641 agagttttag gtatttcatt tgaagaagga gaaaatatcg atttgtatca aaataaaggt
    77701 cgttttttat acaaatatgc tggttaattt ttagaagaag ctgcagtact atgctttaac
    77761 gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc ctaattctga aagtacaaaa
    77821 cctaagactt ttgaaattga ttgtttagtc ggagaaaaac acgcatacga aataaaatgg
    77881 tgggatgcaa ctacagatgg agaccatata actaaagaac acactagaat aaaagttatt
    77941 cataacaaag gatatatacc aattcggtta atgttctact atccaaatag aactcaagct
    78001 ataaaaattc agcaaacttt agaaacattg tataacggta ttggagggaa atattattat
    78061 ggagattctg cctgggaaca tttaagagca gtgaccggta ttgatttact tagtattcta
    78121 acagatattg caaataaaaa aacaggggta aaatcaaaat gacagtatta aaaggagata
    78181 acttagaaat attaaaaact attgaatcct caagtattga tttaatctat atggaccctc
    78241 ctttctttac acagaaaacc caaaaattat ctaataacaa aaatattatg tattcattcg
    78301 aagatacgtg gacttcgatt gaggattaca aagaattttt gtctgtaaga ttagaagaat
    78361 gcaaaagagt gctaaaaaat agtggcagta ttttcgttca ttgtgataaa attgcaaatc
    78421 atcatattag attaatttta gataatatct ttggagtaga tatgtttcaa agcgaaatta
    78481 tatggaacta taaacggtgg tctaattcaa aaaagggatt attgaacaat catcaaaaca
    78541 tttactttta ttcaaagtca aaagatttta aatttaatac aatttttaca gagtattctt
    78601 ctactacaaa tatcgaccaa atactagtgg aacgaaaacg agatggaaac tctaaaacta
    78661 tatataaagt tgataataat ggtaactata ttctagcaaa agagaaaaat ggagttcccc
    78721 tttcagatgt ttggaatata ccatttctta atccaaaagc taaagaaaga gtaggttatc
    78781 ctacacaaaa acctattctg ttattagaac aaattataaa gattgctact gataaaaatg
    78841 atatagtttt agacccgttc tgtggaagtg gaactacttt agtagcctcc aagattttga
    78901 atagaaatta tatggggatt gatttatctg aggaagctat caatataact cagcaacgtc
    78961 tggaaaatgt tataaaaaca agttcaaatt tattgaataa aggaatcgaa gcatatagaa
    79021 ccaaaactga ggaagaggaa aacattctta aattattaca ggcaaaaatt gttcaaagaa
    79081 ataaaggaat tgatggtttt ttacctaaac attttcaaaa aaaaccgata cctataaaaa
    79141 ttcaaaaaaa taatgaatgt ctgaatgaga gtatctcttt attacagaat gctataaact
    79201 ccaaaaaact tgattttgga gtagttataa aaactcattc agataattta ttatttgatt
    79261 ttgatacgat tcctgaaaat ataatagtag ttgaccattt tgaacttaca atcgaaaaat
    79321 ggttaagtaa aagttaacag ttactatagt ttgcaaatta tttacagaaa gaacaagaat
    79381 tcctaggaga ttattctggc tatgttcatt gtgacatgtt gcggcagtaa cttaggactt
    79441 tagtcctcta gttctgccta tgcgatagca gtccaaagtt taggagtaag gcgacgctaa
    79501 gcttggtaaa ctgcgaacag ctagaagctt atcgtcaact ggaagaagct gcacttgttg
    79561 gatgttgggc gcatgtgaga aggaagtttt ttgaagcgac ccccaagcaa gcagataaat
    79621 catccttagg aactaaaggt ttagcttatt gtgatcagtt attttccttg gaaagagact
    79681 gggaggcttt gccagctgat gaacgactac agaaacgtca agaacatctc caacccctac
    79741 tggaagactt ctttgcttgg tgccgtcgtc agtcagtttt atcgggttca aaactaggaa
    79801 gggcaattga atacagcctc aagtatgaag aaacctttaa gaccatttta aaagacggac
    79861 atctggtcct ttccaataat ctagctgaac gcgccattaa atcattggtt atgggacgta
    79921 aaaattggtt gttttctcaa agttttgaag gagctaaagc aagagctatt attatgagct
    79981 tattggaaac agctaaacgt catcaactaa atagtgagaa atatctatcc tatcttctag
    80041 aatgtcttcc aaacgaggaa actctcgtaa acaaagaggt tttagaggcc tatttaccgt
    80101 ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga actatatatg
    80161 agttctctag tctggagatt tttcaatata cttcgttatt gggcggttac aatttattat
    80221 atgaaaatcc catatcattc tccaattcta tattttacct ttctaaatgt atagattaac
    80281 tacctaatta tatcatataa cgcagattcc tttcaatcgt atgatttact gcattaaatt
    80341 aagtaaaaaa ataaaggcag tccgaagact gccgatattt atctctcatc tcttta
//
LOCUS       DBEJJE010000002        80370 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEJJE010000002 DBEJJE010000000
VERSION     DBEJJE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.02"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..134
                     /locus_tag="ACL3F5_000077"
                     /pseudo
     CDS             1..134
                     /locus_tag="ACL3F5_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            137..1148
                     /locus_tag="ACL3F5_000078"
                     /pseudo
     CDS             137..1148
                     /locus_tag="ACL3F5_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1123..1701
                     /locus_tag="ACL3F5_000079"
     CDS             1123..1701
                     /locus_tag="ACL3F5_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGR0513956.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIAFKDLEKVREAFKKMNSTWTINESVV
                     RYNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(1758..2000)
                     /locus_tag="ACL3F5_000080"
     CDS             complement(1758..2000)
                     /locus_tag="ACL3F5_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0513957.1"
                     /translation="MKKDIHPEYRSVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2096..3031)
                     /locus_tag="ACL3F5_000081"
     CDS             complement(2096..3031)
                     /locus_tag="ACL3F5_000081"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0513958.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3135..3578
                     /locus_tag="ACL3F5_000082"
     CDS             3135..3578
                     /locus_tag="ACL3F5_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0513959.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3694..3960
                     /locus_tag="ACL3F5_000083"
     CDS             3694..3960
                     /locus_tag="ACL3F5_000083"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0513960.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3957..4331
                     /gene="crcB"
                     /locus_tag="ACL3F5_000084"
     CDS             3957..4331
                     /gene="crcB"
                     /locus_tag="ACL3F5_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0513961.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTLLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            4325..4654
                     /gene="crcB"
                     /locus_tag="ACL3F5_000085"
     CDS             4325..4654
                     /gene="crcB"
                     /locus_tag="ACL3F5_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0513962.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4773..5120
                     /gene="rplS"
                     /locus_tag="ACL3F5_000086"
     CDS             4773..5120
                     /gene="rplS"
                     /locus_tag="ACL3F5_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0513963.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5163..5234
                     /locus_tag="ACL3F5_000087"
     tRNA            5163..5234
                     /locus_tag="ACL3F5_000087"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5196..5198,aa:Arg,seq:cct)
     gene            complement(5406..6404)
                     /locus_tag="ACL3F5_000088"
     CDS             complement(5406..6404)
                     /locus_tag="ACL3F5_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGR0513964.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LPTSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSILNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHS
                     LIYYIESLIITSSGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPCSTAEEINNYLKKYECYSPLNNLELDDVE"
     gene            complement(6447..7253)
                     /gene="yidA"
                     /locus_tag="ACL3F5_000089"
     CDS             complement(6447..7253)
                     /gene="yidA"
                     /locus_tag="ACL3F5_000089"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0513965.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(7266..8570)
                     /locus_tag="ACL3F5_000090"
     CDS             complement(7266..8570)
                     /locus_tag="ACL3F5_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0513966.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            8642..9019
                     /locus_tag="ACL3F5_000091"
     CDS             8642..9019
                     /locus_tag="ACL3F5_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0513967.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            9110..9442
                     /locus_tag="ACL3F5_000092"
     CDS             9110..9442
                     /locus_tag="ACL3F5_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0513968.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            9454..11025
                     /gene="ffh"
                     /locus_tag="ACL3F5_000093"
     CDS             9454..11025
                     /gene="ffh"
                     /locus_tag="ACL3F5_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0513969.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(11220..12503)
                     /locus_tag="ACL3F5_000094"
     CDS             complement(11220..12503)
                     /locus_tag="ACL3F5_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0513970.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(12757..13470)
                     /gene="rsmG"
                     /locus_tag="ACL3F5_000095"
     CDS             complement(12757..13470)
                     /gene="rsmG"
                     /locus_tag="ACL3F5_000095"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0513971.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            13564..14124
                     /locus_tag="ACL3F5_000096"
     CDS             13564..14124
                     /locus_tag="ACL3F5_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0513972.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            14126..15025
                     /gene="htpX"
                     /locus_tag="ACL3F5_000097"
     CDS             14126..15025
                     /gene="htpX"
                     /locus_tag="ACL3F5_000097"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0513973.1"
                     /translation="MLFNQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(15069..16628)
                     /locus_tag="ACL3F5_000098"
     CDS             complement(15069..16628)
                     /locus_tag="ACL3F5_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0513974.1"
                     /translation="MYYRHSRKGNSMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(16867..17184)
                     /locus_tag="ACL3F5_000099"
     CDS             complement(16867..17184)
                     /locus_tag="ACL3F5_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0513975.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            17363..17905
                     /locus_tag="ACL3F5_000100"
     CDS             17363..17905
                     /locus_tag="ACL3F5_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0513976.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            17905..18534
                     /gene="nth"
                     /locus_tag="ACL3F5_000101"
     CDS             17905..18534
                     /gene="nth"
                     /locus_tag="ACL3F5_000101"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0513977.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            18745..19266
                     /gene="pyrR"
                     /locus_tag="ACL3F5_000102"
     CDS             18745..19266
                     /gene="pyrR"
                     /locus_tag="ACL3F5_000102"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0513978.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            19285..20208
                     /locus_tag="ACL3F5_000103"
     CDS             19285..20208
                     /locus_tag="ACL3F5_000103"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0513979.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            20258..21337
                     /locus_tag="ACL3F5_000104"
     CDS             20258..21337
                     /locus_tag="ACL3F5_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0513980.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            21650..24826
                     /gene="carB"
                     /locus_tag="ACL3F5_000105"
     CDS             21650..24826
                     /gene="carB"
                     /locus_tag="ACL3F5_000105"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0513981.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(25101..25910)
                     /locus_tag="ACL3F5_000106"
     CDS             complement(25101..25910)
                     /locus_tag="ACL3F5_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0513982.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
     gene            complement(25912..26715)
                     /locus_tag="ACL3F5_000107"
     CDS             complement(25912..26715)
                     /locus_tag="ACL3F5_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0513983.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(26725..28212)
                     /gene="tacF"
                     /locus_tag="ACL3F5_000108"
     CDS             complement(26725..28212)
                     /gene="tacF"
                     /locus_tag="ACL3F5_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0513984.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            28548..29255
                     /locus_tag="ACL3F5_000109"
     CDS             28548..29255
                     /locus_tag="ACL3F5_000109"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0513985.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            29260..30282
                     /locus_tag="ACL3F5_000110"
     CDS             29260..30282
                     /locus_tag="ACL3F5_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0513986.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            30299..31168
                     /gene="licA"
                     /locus_tag="ACL3F5_000111"
     CDS             30299..31168
                     /gene="licA"
                     /locus_tag="ACL3F5_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0513987.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            31158..32036
                     /locus_tag="ACL3F5_000112"
     CDS             31158..32036
                     /locus_tag="ACL3F5_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0513988.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            32048..32737
                     /locus_tag="ACL3F5_000113"
     CDS             32048..32737
                     /locus_tag="ACL3F5_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0513989.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            32833..33681
                     /gene="dprA"
                     /locus_tag="ACL3F5_000114"
     CDS             32833..33681
                     /gene="dprA"
                     /locus_tag="ACL3F5_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0513990.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            34565..35608
                     /locus_tag="ACL3F5_000115"
     CDS             34565..35608
                     /locus_tag="ACL3F5_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR0513991.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            35775..37862
                     /gene="topA"
                     /locus_tag="ACL3F5_000116"
     CDS             35775..37862
                     /gene="topA"
                     /locus_tag="ACL3F5_000116"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0513992.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            38083..38442
                     /locus_tag="ACL3F5_000117"
     CDS             38083..38442
                     /locus_tag="ACL3F5_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0513993.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            38535..39167
                     /locus_tag="ACL3F5_000118"
     CDS             38535..39167
                     /locus_tag="ACL3F5_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0513994.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            39211..39867
                     /locus_tag="ACL3F5_000119"
     CDS             39211..39867
                     /locus_tag="ACL3F5_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0513995.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            39937..40980
                     /locus_tag="ACL3F5_000120"
                     /pseudo
     CDS             39937..40980
                     /locus_tag="ACL3F5_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            40992..42029
                     /gene="leuB"
                     /locus_tag="ACL3F5_000121"
     CDS             40992..42029
                     /gene="leuB"
                     /locus_tag="ACL3F5_000121"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGR0513996.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            42026..42295
                     /locus_tag="ACL3F5_000122"
     CDS             42026..42295
                     /locus_tag="ACL3F5_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0513997.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            42299..42658
                     /locus_tag="ACL3F5_000123"
     CDS             42299..42658
                     /locus_tag="ACL3F5_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0513998.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKFLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            42820..43443
                     /locus_tag="ACL3F5_000124"
                     /pseudo
     CDS             42820..43443
                     /locus_tag="ACL3F5_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            43609..45522
                     /locus_tag="ACL3F5_000125"
     CDS             43609..45522
                     /locus_tag="ACL3F5_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0513999.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENSIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            45509..46825
                     /locus_tag="ACL3F5_000126"
     CDS             45509..46825
                     /locus_tag="ACL3F5_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0514000.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKILHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            47000..47986
                     /locus_tag="ACL3F5_000127"
     CDS             47000..47986
                     /locus_tag="ACL3F5_000127"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0514001.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            48050..48121
                     /locus_tag="ACL3F5_000128"
     tRNA            48050..48121
                     /locus_tag="ACL3F5_000128"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48083..48085,aa:Arg,seq:ccg)
     gene            48304..49002
                     /gene="rnc"
                     /locus_tag="ACL3F5_000129"
     CDS             48304..49002
                     /gene="rnc"
                     /locus_tag="ACL3F5_000129"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0514002.1"
                     /translation="MKELQTVLKNHFAIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            48993..52532
                     /gene="smc"
                     /locus_tag="ACL3F5_000130"
     CDS             48993..52532
                     /gene="smc"
                     /locus_tag="ACL3F5_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0514003.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLTDYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELDNLNLAEQEVQDLEK
                     AIRSLGPVNLDAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            52529..53323
                     /locus_tag="ACL3F5_000131"
     CDS             52529..53323
                     /locus_tag="ACL3F5_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0514004.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMERLKSLLTSYKEKGIYFAVAS
                     GRGFLSLEKLFADVRNDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLQTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARSEILELAETVIGHHKDQSVIAYMEGL"
     gene            53323..54141
                     /locus_tag="ACL3F5_000132"
     CDS             53323..54141
                     /locus_tag="ACL3F5_000132"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0514005.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            54145..55434
                     /gene="ftsY"
                     /locus_tag="ACL3F5_000133"
     CDS             54145..55434
                     /gene="ftsY"
                     /locus_tag="ACL3F5_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0514006.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVIFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(55480..56967)
                     /gene="zwf"
                     /locus_tag="ACL3F5_000134"
     CDS             complement(55480..56967)
                     /gene="zwf"
                     /locus_tag="ACL3F5_000134"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0514007.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(57116..57856)
                     /locus_tag="ACL3F5_000135"
     CDS             complement(57116..57856)
                     /locus_tag="ACL3F5_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0514008.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(57856..60021)
                     /locus_tag="ACL3F5_000136"
     CDS             complement(57856..60021)
                     /locus_tag="ACL3F5_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0514009.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            60190..61143
                     /locus_tag="ACL3F5_000137"
     CDS             60190..61143
                     /locus_tag="ACL3F5_000137"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0514010.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLVFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEELVTRAWLIPQLAKRTNLKVAIIISSSLFTLLHLGNPGITFLS
                     AIDLFLFGVAMSLYLLKTDTIWGIGGIHGAWNFAQGNLFGVLVSGQSSGTSIMRFTPQ
                     GNQDWLSGGSFGIEGSIVSSIILFLLILYLAHQLKKENERM"
     gene            61220..63208
                     /gene="uvrB"
                     /locus_tag="ACL3F5_000138"
     CDS             61220..63208
                     /gene="uvrB"
                     /locus_tag="ACL3F5_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0514011.1"
                     /translation="MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQTELEEQL
                     AVFENEGKLLESQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEGEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKTVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            63218..63781
                     /locus_tag="ACL3F5_000139"
     CDS             63218..63781
                     /locus_tag="ACL3F5_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0514012.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKIAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDDYYQINENS"
     gene            63747..64235
                     /locus_tag="ACL3F5_000140"
     CDS             63747..64235
                     /locus_tag="ACL3F5_000140"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514013.1"
                     /translation="MTIIIKLMKTPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSKKYPENTWIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKVALTALDHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            64307..64774
                     /locus_tag="ACL3F5_000141"
     CDS             64307..64774
                     /locus_tag="ACL3F5_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0514014.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(64771..65286)
                     /locus_tag="ACL3F5_000142"
     CDS             complement(64771..65286)
                     /locus_tag="ACL3F5_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0514015.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(65298..65825)
                     /locus_tag="ACL3F5_000143"
     CDS             complement(65298..65825)
                     /locus_tag="ACL3F5_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0514016.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWIFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(66107..66670)
                     /locus_tag="ACL3F5_000144"
     CDS             complement(66107..66670)
                     /locus_tag="ACL3F5_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0514017.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(66654..67205)
                     /gene="coaC"
                     /locus_tag="ACL3F5_000145"
     CDS             complement(66654..67205)
                     /gene="coaC"
                     /locus_tag="ACL3F5_000145"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0514018.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(67217..67906)
                     /gene="coaB"
                     /locus_tag="ACL3F5_000146"
     CDS             complement(67217..67906)
                     /gene="coaB"
                     /locus_tag="ACL3F5_000146"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0514019.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGYEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            68136..69806
                     /locus_tag="ACL3F5_000147"
     CDS             68136..69806
                     /locus_tag="ACL3F5_000147"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0514020.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNLVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            70134..71309
                     /gene="mutY"
                     /locus_tag="ACL3F5_000148"
     CDS             70134..71309
                     /gene="mutY"
                     /locus_tag="ACL3F5_000148"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0514021.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            71364..72068
                     /gene="yycF"
                     /locus_tag="ACL3F5_000149"
     CDS             71364..72068
                     /gene="yycF"
                     /locus_tag="ACL3F5_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0514022.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            72061..73410
                     /gene="vicK"
                     /locus_tag="ACL3F5_000150"
     CDS             72061..73410
                     /gene="vicK"
                     /locus_tag="ACL3F5_000150"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0514023.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            73412..74221
                     /locus_tag="ACL3F5_000151"
     CDS             73412..74221
                     /locus_tag="ACL3F5_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0514024.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            74312..74554
                     /gene="relB"
                     /locus_tag="ACL3F5_000152"
     CDS             74312..74554
                     /gene="relB"
                     /locus_tag="ACL3F5_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0514025.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            74556..74810
                     /locus_tag="ACL3F5_000153"
     CDS             74556..74810
                     /locus_tag="ACL3F5_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0514026.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            74857..75630
                     /locus_tag="ACL3F5_000154"
     CDS             74857..75630
                     /locus_tag="ACL3F5_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel"
                     /protein_id="HGR0514027.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(75893..76879)
                     /locus_tag="ACL3F5_000155"
     CDS             complement(75893..76879)
                     /locus_tag="ACL3F5_000155"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0514028.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            77073..79541
                     /gene="gyrA"
                     /locus_tag="ACL3F5_000156"
     CDS             77073..79541
                     /gene="gyrA"
                     /locus_tag="ACL3F5_000156"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0514029.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            79541..80284
                     /gene="srtA"
                     /locus_tag="ACL3F5_000157"
     CDS             79541..80284
                     /gene="srtA"
                     /locus_tag="ACL3F5_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0514030.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        24503 a        14295 c        17636 g        23936 t
ORIGIN      
        1 gccacgtcca gaacatccta agaaagcaga cgctcaaacc attgtcgcgt ctaaaaataa
       61 aatctcaatt caagaagaca agaaagcggt ttaaatatag tagacgtttt cgtaaggttc
      121 gcttgatgta ccaaatagta cgcccatgca aaagaatatc tattttgttg tcttggacct
      181 gcatacgacg gatagagata aaattatcca gctattcaag gattggacgg attatagtgc
      241 caagttggtc gagggggaat tggttaaaaa agatggacag aatgctctct ttcctccgag
      301 cgatactggt gagacagttg ggctcaatcc tcatcgtttg acgctgactt ttggtgtatc
      361 tgcaagtttc ttgaaaaaga tgaacttgga aaacaagcgc cctcgactgt tcagggattt
      421 acctctattt cctaaggagc aattacgtga aaaatatact ggtggagata ttgtgattca
      481 tgcttgtgca gatgatgagc aaattgcctt tcacgttatt cgcaatctca tacgtaaggg
      541 gagaaatgcg gtgccccttc gttggagtca gtctggattt gcagctatcg gggacgaatg
      601 gagactccgt ggaacctctt tggttttaag gatggaacag caaattcaac caaggagcaa
      661 gactttgacc gcgttatctg ggctgatagt aaggactgga tggaaaatgg ttcttatatg
      721 gcagttcgtc ggattcagat gtttttagag acctgggacc gcactggtct cgaagaacaa
      781 gaaaatacct ttggtcgtta caaggaaagt agtgcccctt tcggtaaaaa aatgagtttg
      841 atgaagtgaa tttgagtttt ttgctagatg attcgcatgt tcgtttggct aagtaagtgg
      901 acaagccact tttgcgttgt tcttactctt actcagatgg cattgatgaa aagactggtc
      961 agtttgatac gggattgctc ttcatttctt tccagaagga tcctgataac tttgttaagg
     1021 ttcaaactaa cctaggtgct actgataaga tgaatgaata catcactcac ataggtagtg
     1081 gactttttac ttgctttggt ggtgtggaga aaggaggcta cattggtcag aaattattgg
     1141 aaggctaaaa gctggttact agttttagct ttgtcatttt taattctttc cccagcaggt
     1201 gcccaagaaa gcttgagttt tttctttgtg aaaatcacag atgcatccaa agcggttaaa
     1261 aatggtggtc agactgagac ccagaaactc gttacgaaga tggcatcaga cttcgaaaga
     1321 gtagaaaata aggattctga ggttggtaag attgttaagg aaaagttagc tctatctgga
     1381 gatattactg aagccaaact caccgaaatt tcctcagctc tattagcttt tgaaaaagaa
     1441 caaaatcctg ttgacctaga tgcggaaaag gaaaaattgg taaaccgtct aagtcctcgt
     1501 tttgaaacct tggaacaggc tattgccttc aaagatttgg aaaaagtccg agaagctttt
     1561 aagaaaatga attccacttg gaccatcaat gaaagtgtgg ttcgttacaa tagtatagct
     1621 cattatggac gtgttgaaac agctatttcc ttcctgccta gtagcatgga aaccgaacct
     1681 acagatgagt ctggaacatg aaaacagcag ttgatttcaa gaaacaaaaa agaacagccg
     1741 aaactgttct cttatcatta tttgagaccg tattttttgt tgaaacgatc cacgcgtcca
     1801 tctgcttgag tgaacttttg acgtccagtg tagaatgggt gtgagtctga tgaaatttcc
     1861 acacggatca atgggtaagt ttcgccttcg aactcaactg tttcgttaga gcgttttgtt
     1921 gaaccgctaa ggaattggta accagtagtt gtgtccatga agacaactga gcgatattct
     1981 ggatggatat cttttttcat tttgcaatat ttcctttctg ccatggtctc tttgcgagcc
     2041 atagattgtt accatactag tctatcagat tctgaaaagt ttggcaagta ttttatcagt
     2101 ttttaagcaa gttttttaac ttttggtaga tgatttcgtt ttcttctagg ctataggaat
     2161 tagcaccact tgctagaggg tggcctccac catcatgctc cttggcgatt tcattgatag
     2221 gatggatttt actgcgtaag cgaacgcggt agtggccatc agcctgttcg acaaaaattc
     2281 cccagagact cactctgtca atgcgtccag gtgcaccgac aatggctgca gtttcagcat
     2341 cggttacatt gtattgtttc aagacttctt gactcaggat aacgcgagca gcaccatttt
     2401 catccacttc cagatggtcg tagatgtagc cttgcagttt agcaattttg tagctcatag
     2461 tgtccatttt gcgagtgaga gccgcaaagt caaagttatg ttctctcaaa taagcagcca
     2521 ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg acctgtatca ccgacaattc
     2581 ctgcaaagag caactcagca tcgcgatctg ccaaggctag ttgggttgtt tgggcaaata
     2641 gggtgatcat ctcgctagcg ctacttgaac tagtatcgac ccaagacagg tcaccgtata
     2701 catcatcatt tggatggtgg tcaatcttaa tgagaaaatc accttgacta tagcgcttat
     2761 catcgatacg agcagtatta gctgtatcac agacgatgac aagtgcgcct tggtaggctc
     2821 tatcttcaac aagatccatc tcagccatcc aagtaagagt tggttcatca aaaccgacgg
     2881 ctttgatggt tttttctggg aaatgatgtt ccagcaaggc tttcaatccc acctgacttc
     2941 ctaaggcatc agggtctggt ttcatatgac gatgaatgat aatggtgtcg tattctttaa
     3001 ttttttctaa aatttgttgg caaatctcca taaataacct caattctttc tcatttcatt
     3061 gtagcacaag aatttttatt tttaaaatga aaaagatgtg atataatgga gaaagataaa
     3121 ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc cagtatgacc ggtaataccg
     3181 aagaaattgc agatattgta gcagacaaat tacgtgactt gggcttggat gttgatgttg
     3241 atgaatgtac aactgttgac gcttcagact tcttggaagc agacatcgct atcgttgcga
     3301 cctatactta tggtgatggt gaattgccag atgagatgat ggacttctac gaagacctag
     3361 cagatctcaa cttgaatggc aaaatctacg gagtggtcgg ctcaggagat accttctacg
     3421 atgaattctg taaggctgtt gatgactttg accgtgtctt tgtgtcaaca ggagcagaaa
     3481 aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga agaagatatt gaacgcttgg
     3541 aacaattcgc agaagaattg gttgctaaag taggataagc ataaaagtgc gctgatgtaa
     3601 tcaatcagtg catttttctt atcgagagtt gggattttac tagcctaatt gatggctttt
     3661 tgatacaata attcaaataa aggaggagac tgtatggatt tagatattat tcgtcaagaa
     3721 atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag aacgaatgca cttagttgaa
     3781 ggagttgtcg cttataagaa ggcttcaggg aaaccgattt tagatactaa gagagaagca
     3841 gttatttttg aaaaggttag aagtcgtgta gaggacaagc gctatcagga gactattgtc
     3901 gcgacttttt cggacatact caaacgttcg cgtgattatc aggatcaaaa tatcaaatga
     3961 aaaaagaaca attttatccg ctagggattt ttctagctgc tatgttgggc ggacttgtcc
     4021 gctacctagt ttccactttg ttaccagcca gtccagattt cccttggggc actctctttg
     4081 tcaactatct gggaattttc tgcttgattt atcttgtcaa gggctatctg gtctataagg
     4141 ggactagtaa gggcttgatt ttagcactgg ggacgggttt ttgcggaggt ttaacaactt
     4201 tttccagcct aatgcttgat actgtgaagc tgcttgatac agggcgttat cttagtttga
     4261 tactgtattt gcttttgagt atcggtggag gcctgctttt agcttactat ttggggagga
     4321 agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg ggagcactcg tacggtattt
     4381 cttttctcgc tataatcaag cttctaaatt gccactcgga acgctcatag ctaatctttt
     4441 aggttgtttt ttaattggag tattctacaa tcatgtagag tctaaggaag tatatgctat
     4501 tctagcaaca ggattttgtg gcggtttaac aactttttcg accttgaatg acgaacttca
     4561 aagactgcta agtgataaga aggtctttta ttcttacctg actttgactt acataggtgg
     4621 tttggttgcg atttttttag gaattttgct ataaatttct ttactttttt ttagaaattt
     4681 ggtaaactat atcttgtgtg taatggacgc acaaaaatac agtttatccg ctgaggaaga
     4741 ttcctcaaga ttgacaaaga taggagaata aaatgaatcc attaatccaa agcttgactg
     4801 aaggtcaact tcgtacagat atcccatcat tccgtcctgg tgacactgtt cgtgtacatg
     4861 cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt tgaaggtgtt gttatcgcac
     4921 gtaaaggtgc tggaatctca gaaaactaca cagttcgtaa aatctctaac ggtgtaggtg
     4981 ttgagcgtat cttcccaatc cacactccac gtgttgaaaa aatcgaagtt gttcgttacg
     5041 gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct tcaaggtaaa gcagctcgta
     5101 tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct catttagcag agtttttatc
     5161 tagctccctt agttcaatgg atataacaac tccctcctaa ggagtagttg caggttcgat
     5221 tcctgcaggg ggcagtaatt agacatcaaa gaagtttgtc aaaaagtctt tgatattaaa
     5281 agaacgcata atataggtga ttttgtgtgt ctccataata ttatgcgttt tattattgaa
     5341 aaatttgggc aatcatcaga taaaattgag actatatcga gtatataaat gtttgtataa
     5401 ttaatttatt caacatcgtc aagttctaaa ttatttaaag gactataaca ttcatatttc
     5461 tttaagtaat tgtttatttc ttcagcagta gaacaaggta aattaactct taaatagtca
     5521 atatcttctt tagataaaaa atgatttgca ttcaaaattg agaagcgaaa taatgcttca
     5581 tcaaaagcaa aatcataatc gtcatcagat aatgattcca ttaatgtttg aatatgtttt
     5641 agtgagtagt caggtatcga atcgggataa tatactggat aatcagtggc tgaaaaattg
     5701 ttttctaatc ctgaactagt aattatcaaa gattctatgt aatatattaa agaatgttta
     5761 atattacctt cttgttccaa atgtcttcct tgagcctttc gtgtgttaga taaacatcca
     5821 aaatctcctg atacagtatt cctatgagct tgtttattta aaatactcca ttttatatca
     5881 ccaaaagttg ctttaaaaga gatattattt ttttctttac aataatcttc catagttatg
     5941 tctttatcat agtatgcttt gatatagtca ctatgttcga taataagatt ttgtgcttct
     6001 tttgttagtt taaattcgaa cggaatatct aatttgtcaa cgttgatatt attaattatt
     6061 cttgtaatta attctgcttt ttttccagaa gtaggtaaat tatgtttaga taatatagtt
     6121 tttaattcta ctactttaag atatgataaa gtcttatttt tagtgaagta tcctaatttg
     6181 tataattgat tgtgtgtaga ttcagggtca atttgaagag agtatttaaa atatcttggg
     6241 aaattataat ttctccctgt tttttgagtc caatctatga gtatgagttg cccaggagta
     6301 aggccgcact ctaatttgtt taggtaaaaa ttgttacaat cagaatttgt gtctctatta
     6361 tgattatttt gttttaaatt aaatagtttg ctaaaaaaat tcattggatt ttattgctaa
     6421 tcaattctta ttgaaaaatg atacttttac agtacccatg tacggatggc atgggcaacg
     6481 ccagattcat cattagattt agtgatgtat ttggcgattt ttttgatttc tggatttcca
     6541 ttttccatga caacagggtt gccaacgact tccagcatgg cacggtcatt ttcttcgtct
     6601 ccgatagcca tggtttcatc tttggttaat cctagttttt cagctaagtg agtaatagct
     6661 gaacccttgt ctacattctt tttaaggagt tcgaggtaga aaggagcaga tttgttgata
     6721 gagtagtgct cgtaaaattc ggctggtatt ttttcaatcg cagcatcgag aatttctggt
     6781 tcatcgataa acatacattt aacaatttct ttgccagcca tttcttcagg ggtacggtag
     6841 aagataggca tgctgacgag ggttgattcg tgtacagtgt atgttccgat attgcgattt
     6901 gcagtataga taccgtcctt ggtaatggca tgcatgtgga caccgagctt gcgactgagg
     6961 aattccatat ccagataatc ctcataggtc aaggattcgc tgataatctc atggccagta
     7021 gcagtttctt ggacaagggc accattgaag gtcaccacat agtcaccttg gtctctcaac
     7081 tgcaagtcgt ctagaagttt ggcaacacct gcgatggggc ggccagttgc aatcacgact
     7141 ttgacaccag cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt
     7201 tggctgttga caagggttcc gtcgatatca acggcaatta gtttaatact cataaatttc
     7261 ctcttctagt ttttatttgg ggtaaaatga tcgttctcaa tcaagtataa aaattgctgg
     7321 gtaatgctag caaagatact gttttgatct aacatttctt tcggaaaata gaaacgatta
     7381 tctccgtgac gactaccagc aagggattgg acgataggag acaggctaga gagttcggcc
     7441 agttctccat tcttttgtaa aatctcaatc tgtgtccgtg gattttcaga ttcgggacga
     7501 tagatatcat aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag
     7561 ccaatgtcct caaccaattt tctcatgcta gcgagttggt cttgatcttc ttgtgaaaag
     7621 gtaatggatt taaagacctt gcggttgaca aagcgttgcg ataaatctgc gagaattttg
     7681 tcaggactgg tcatccagag ctggaagtag gtattcatca caccatcatc tagagccaga
     7741 tagtcagaca aggtcacatt tttttcaaag aaaggcagga ggtgtgggga agttcgtgca
     7801 aagaagtctt tgtccttagg gtagagttcc ttagcgcgct tgagaagatt ctgtaggaga
     7861 acttccatag cgcgtgttgc tgggtggaaa tagacctgca tatacatctg gtagcgactg
     7921 aggacatagt cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata
     7981 ggacgaatga ctcggaggat tcgagtcagg tcaaattccc cataggatgc tcctgtaaaa
     8041 taggagtcac gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagttgt
     8101 acgacctgct tgttaggata ggtatggtct atgacactgg caactttctc tggaaaatcg
     8161 ggcgctactt gtagcaatac ttggtgaatc tctgtctcag gactttgaat aatctcctga
     8221 gtaatagctt catggtctgt atcaaagaga tgttcaaaag tatgggagta ggcgccatgc
     8281 ccaaggtcat gtaggagagc agcgatcatg gtcaagagag actcggcagg attccattcc
     8341 tcaggatatt tttcttcgaa aatctctgtg atgcgtcgtg caatttcata gactcctaga
     8401 cagtgagaga agcgactgtg ttctccaccg tggaaggtat aactggaagt tcccagttgt
     8461 ttgatccggc gcaaacgctg aaattctttt gtattaatca agtcatagat gatttgatta
     8521 ttgacatgga tgtagttgtg aactgggtca cggaatactt tttcgttcat atgaccatta
     8581 tagcaaaatc ctgctctttt tggtaaaata gtaggacaag agacaagaaa gagggcctga
     8641 tgtgaagatt cggatgcgaa atacaattca gtttgatgag cagttggaag tgattgacca
     8701 gctttatgat gtggaagtgc atgaaaaagg agattatagc tacctgcttt tctataatga
     8761 ggaaaaggaa aaagtagtga ttaaatttca tggtcaagaa cttgtgatga gccgattttc
     8821 taatcccaag accattatgc gctttctaaa gaatagcgat agtttagcct atattcctac
     8881 acctatgggc atgcaggagt ttatcatcca aacgagccat tatcaagttg ataggcaaaa
     8941 gattgaacta gattatcaac tacaaaatca agagggacat ccttttgcca gctatcaatt
     9001 ggaaattact tggggctagg ctcatgtctt tttcaaattt agctatctat cttcttggat
     9061 cggcttccta gtgtggtaga ttaggctaat ttttggtata ataaaagtta tggaaatcga
     9121 aaaaaccaat cgtatgaatg cgctctttga attttatgcg gcgcttttga cagataagca
     9181 aatgaattat atcgagctct actacgctga tgattacagc cttgctgaaa ttgccgagga
     9241 gtttggtgtc agtcgtcagg ctgtctatga caatatcaag cgaacagaaa agattctgga
     9301 agattatgag atgaaattgc acatgtactc ggactatatt gtccgcagtc agatttttga
     9361 tcagattttg gagcgctatc ccaaggataa ctttctgcag gagcagatag aaattttaac
     9421 aagcattgat aatagagaat aagaggaaga aaaatggcat ttgaaagttt aacagaacgt
     9481 ttgcagaacg tctttaaaaa tctacgtaaa aaaggaaaaa tctctgaatc tgatgtccaa
     9541 gaggcaacca aagaaattcg cttggccttg ctcgaggccg acgttgcctt gcctgttgta
     9601 aaggacttta tcaagaaagt tcgtgagcgt gcagtcgggc atgaggtcat tgatacactt
     9661 aatcctgcgc aacagattat taaaatcgtt gatgaggaac tgacagccgt tttaggttct
     9721 gatacggcag aaattatcaa gtcacctaag attccaacca tcatcatgat ggttggttta
     9781 caaggggctg gtaaaacaac ctttgctggt aaattggcca acaaactcaa gaaagaagaa
     9841 aatgctcgtc ctttgatgat tgcggcggat atttatcgtc cagctgccat tgaccagctt
     9901 aagaccttgg gacaacagat tgatgtgcct gtctttgcac ttggaacaga agtaccagct
     9961 gttgagattg tacgtcaagg tttggagcaa gcccaaacta atcataacga ctatgtcttg
    10021 attgatactg cgggtcgttt gcagattgat gagctcctca tgaatgagct tcgtgatgtg
    10081 aaagcattgg ctcaaccaaa tgaaatcttg cttgtcgttg atgctatgat tggtcaggaa
    10141 gcagccaatg ttgcgcgtga gtttaatgct cagttggaag tgactggggt catccttacc
    10201 aagattgatg gcgatactcg tggtggtgct gctctgtctg ttcgtcacat tactggaaaa
    10261 ccaatcaagt tcactggtac aggtgaaaag attacggaca ttgaaacctt ccacccagac
    10321 cgcatgtcta gccgtatcct tggtatgggg gatatgctca ctttgattga gaaagcttct
    10381 caggaatacg atgaacaaaa agcccttgaa atggctgaga agatgcgcga aaacaccttt
    10441 gattttaatg atttcatcga tcaattagat caggtgcaaa atatggggcc gatggaagac
    10501 ttgctcaaga tgattccagg tatggccaac aatccagcac ttcaaaacat gaaggtggat
    10561 gaacgccaga ttgctcgtaa acgtgccatt gtgtcttcga tgacacctga agaacgtgaa
    10621 aacccagatt tgttaaatcc aagccgtcgc cgtcgtattg ctgctggttc tggaaataca
    10681 ttcgtcgaag tcaataaatt catcaaggac tttaaccagg ctaaacagct catgcagggt
    10741 gttatgtctg gggatatgaa taaaatgatg aagcaaatgg ggattaatcc aaataacctt
    10801 cctaaaaata tgccaaatat gggaggaatg gatatgtctg cccttgaagg aatgatggga
    10861 caaggcggta tgcctgactt atcagctctc ggaggagcag gaatgccaga tatgagccag
    10921 atgtttggtg gcggtttgaa aggtaaaatt ggtgaatttg ccatgaaaca gtccatgaaa
    10981 cgtatggcta acaaaatgaa gaaagcgaag aagaaacgca agtaagacaa gagattgatg
    11041 caaatctcat ttgatgagaa aataaagtaa aaatttctat gataaaacgt acagtatcaa
    11101 ggttttagaa tatctgatat tatacgtttt ttgattttaa taattttgtt aagacacttt
    11161 tattatggta tgcgaaaaat ccactcagct gtctgagtgg attaggtgta tttagactct
    11221 tagtctttat tttcgtatgg caagatcaag ttcaagatga ttcctgtcat ggctgaaagg
    11281 gcagtacctg aaagtgtaac tggaccaagt ttaaggatag ctcctccaag tccaagaacc
    11341 aacatagcac ttgcgatgat gaggtttcgc atttgagcga aatcaacacg ttctttaatc
    11401 aagactttca aaccattgct ggcgataacc ccatagagaa ggattgacat accaccaagt
    11461 acagcgtttg gaatagttga aatcaaggca gtgaatttac caaggaagct gagggcaatc
    11521 gcgatgaagg cagcgttacg gataactgag acagaagcga tacgagtcat accgataacc
    11581 cctgtatttt ctccgtaagt tgtattggct ggtccaccaa ggaaggcaga aacagaagtt
    11641 gcgataccgt caccaagaag agtacgatga agacctggtt cttttaagaa ttgacggcca
    11701 cagatttgac ccaaaacagt atggtctccg atatgttcag aaattgttac gatagcgatt
    11761 ggcaagatag cgatggcttc tggaccaaag taaagattgt actctttaaa ggcaccacct
    11821 gtgctaaatg gcaagtagaa accaggaatt tcgaaccagt tggctttaag aactggtgta
    11881 aagtcaacca agccaagagt tagtgcgaaa aggtaaccac cgataatggc aaagaggaat
    11941 ggaatgattc gtaggaagcc ttttcctttt gtattgataa aggcagcaat taggaaagta
    12001 acaacggcta ccagagcatt tttccaattt ccgtctgcta caagacctgc attggtaaca
    12061 gctgaacctg caagtccaag accgataacg atgatcatag gaccgataat gattggtggc
    12121 aagagtttat caatccattt tgttcctaca aatcggatgc tggtagcaac aaggacatag
    12181 accaaaccag tcaagataac ccctgtttgg gcagcagata catccccccc catttctttc
    12241 atagccagtg acatagctgt gataaaggca aatgaagaac ctagataaac tggaacttta
    12301 aaaccagtag caatcatgta gatgagtgtt ccaacacctg aagcaaaaag ggcaacagat
    12361 acaggcattc ccaaaatcaa tggtaccaag atggtcgcac caaacatggc gaaaacgtgt
    12421 tggaagctaa ggagaattcc ttttccatcc gaaggacgtt ggtcaacgtc tagtaacaaa
    12481 tcaacagttg attcttgttt catataaacc tcacttttgg gcatcagaaa agagcccatt
    12541 attttacagc aataggccct cagagtaaga cttctctaaa atctagactt taaagagttt
    12601 taaatatttt tgcgtcttcg tcacctcacg ggatgacatt aaaaaccttt gcttaggata
    12661 gtatagcaga aaaaaatgat tttgtaaatc attttttccc gagcctagaa ataaaagagc
    12721 gaggctgatt ttgtaaacat ttgtttacta aaaaatttaa agtgggcgtt tatttggcat
    12781 accagcctta cgtggatatt tatttggtgt ttcttttttc ttttctacca ctgtgatata
    12841 gcgcggatct ctattcggta gggcgtagct gagattgtct tcgaccttac taaaaaggag
    12901 attgagggca ttcttagctt ctaataattc ctcaggcgca ttgctggcct tgagtgccaa
    12961 tagttttcca ccaaccttaa ggtagggaat ggtcaattca gataggacct gcatacgggc
    13021 aaccgcacga gctgttacaa aatcatattg agcacggaag ttcttgtctt gggcaaaatc
    13081 ttcggcacgt ccgtggtaga aatgaactcc gttcaaatcc agttcttgag ccaagagttg
    13141 taggaagttg atgcgcttat tgagtgaatc aataatggtc acatctaact ccggatagag
    13201 aattttcatt ggtagactag gaaatcctgc cccagccccg atatcaagaa gtttgatagt
    13261 ttcattggga atcaaacctt gaagaatggg tgcaatcgaa tcgtaaaaat gtttgagata
    13321 aacttcttcc ttgtccgtaa tcgccgtcaa attaatcttc tcattccact cgaccaagag
    13381 ctcaaaataa cgttcaaatt gttctttttg ctggtccgaa agtggaagat tctgctcggc
    13441 aagcaagttg taaaatgttt ttggtttcat agttatttcc ttctttagta tcatcttatt
    13501 ttaccacaat catagaaaat ttgatatact ggtactaatc taaaagcaga aaggacttat
    13561 attatgactt ggattattct tggagttatc gctcttattg ttatttttgt gattgttagc
    13621 tataacggtt tggttaaaaa tcgtatgcaa accaaggagg cttggagtca gattgatgtt
    13681 cagttgaaac gtcgaaatga cctcttgccg aacttgattg agactgtaaa aggttatgcc
    13741 aaatatgaag gttctaccct tgaaaaggtg gcagaactac gtaaccaagt ggcggcagcg
    13801 acttcaccag cagaagctat gaaagccagt gatgccctca ctcgtcaggt ttcaggtatt
    13861 tttgcagttg cagaaagcta tccagatttg aaagctagtg ctaactttgt taaattgcaa
    13921 gaggagttga caaacacaga aaataaaatt tcttactctc gtcaactcta taacagtgtt
    13981 gtcagcaact acaatgtaaa attagaaact ttcccgagca atattatcgc tggaatgttt
    14041 ggatttaaag cggcagattt ccttcaaaca cctgaagagg aaaagtcggt tcctaaagtt
    14101 gattttagcg gtttaggtga ctaagatgtt gtttaatcaa attgcaagca ataaacgaaa
    14161 aacctggatt ttgttgctgg tatttttcct actcttagct cttgttggtt atgcggttgg
    14221 ttatctcttt ataagatctg gacttggtgg tttggttatc gcactgatta tcggctttat
    14281 ctacgctttg tctatgattt ttcaatcgac agagattgtc atgtccatga atggagcgcg
    14341 tgaggtggat gagcaaacgg caccagacct ctaccatgta gtggaagata tggctctggt
    14401 cgctcagatt cctatgcccc gtgttttcat cattgatgat ccagccttaa atgcctttgc
    14461 gacaggttct aatcctcaaa atgcggctgt tgctgcgact tcaggtctac tagctatcat
    14521 gaatcgtgaa gaactagaag ctgttatggg acatgaagtc agtcatattc gtaattatga
    14581 tatccgtatt tcgactattg cagttgccct tgctagtgct atcaccatgc tttctggtat
    14641 ggcaggtcgt atgatgtggt ggggtggagc aggtcgcaga cgaagtgatg atgaccgaga
    14701 tggaaatggt cttgaaatca ttatgctagt ggtttcccta ctagctattg tactggcacc
    14761 tctcgctgca accttggttc agctcgctat ttctcgtcag agggaatttc tggcagatgc
    14821 atctagtgtt gagctgactc gcaatcccca gggaatgatt aatgccctag ataagttgga
    14881 caatagcaaa ccgatgagtc gccacgtcga tgatgctagc agtgctcttt atatcaatga
    14941 tcccaagaaa ggtggggggt tccaaaaact cttttatacc cacccaccta tctcagaacg
    15001 gattgaacgt ttaaaacaga tgtaaaagaa tccagaggtc gtctctggat ttttgctatg
    15061 ttgcaaattt ataaatcttc taaattaact agcttcaaac cgtgttctgt catgcgatag
    15121 atgatcgagc agacttcttt taagaaacga cggtcatgcg aaacagtgat gagaccgcca
    15181 ggataagtgg caaagagttt tctgatttgg ggttgagaag tgggagaaaa gtttcgtgtg
    15241 ggttcatcca gcaggagaaa gtttggtttg cgcaggacta aatccaaaag caggagtttt
    15301 ccctgttgtc cgccagataa ggagcgaatt tgatgctgca tttctggata actgaaattg
    15361 agactagcta ggtgagattg gattttctgt agttcctctt tttccccagt tttactgaga
    15421 taggctattg gggataaatc caattgcagt tttttgtggt aatcttgtgg cataaaacca
    15481 agtgaaatct ctcttttatc attcagaagt ctctgtaact tggctaacag agttgatttc
    15541 ccaacaccat ttggcccgat aataccgatt ttttcttggc cacggacagt tagttgtagt
    15601 ttttgaacca aaactcggtc gtcaatggac aaattttctt tttccagttg gactaagact
    15661 ttagaagctg gtaatggttg gatgtctgaa aagaaaagtt ggatttgttc ctcttcaagt
    15721 ggcttttgag tcatggactg agctgccttt tcgtagcgtt tttcttgtga gaggacagtt
    15781 ttcatctttt tagccaatag gcgaccggca gtactatctt tggtagctcg aagcgcagtt
    15841 tctacatttt gcttgactct ccgatgtttt ttcatggttt tatcgtaggc tctttggttg
    15901 ttagcagctt gctgactttg tttggcaaaa ttagcctttc tctgctcact atagctatca
    15961 tagtctaaat gctctactag cgtttccgct tctttacggt gtttgaccag tcgcaagtga
    16021 acaatagtgt ctgccgtttc agaaagaaag tcttcatcat gggaaatgaa aataacggtt
    16081 tgcctggtct tttgaatctg gccttttagc caatcaactg tctcaaggtc taggtcattt
    16141 gaaggttcat ctaaaaatag aatctcaaag ggtttggcta actcatggat aagctgaatt
    16201 ttcaaagctt cgccccctga tagattgcca atctcttggt cacttgcgaa acgattgcta
    16261 tcaaaatgca attcctccgc caaacgatag aggatactgt agtctaaatc aatagaatct
    16321 aaaaagaagt agtcgtgtaa agttttcttt tttaggtcct cagggacttt ttgaggaatg
    16381 taggccagtg actgataatc agactggatg tctcccttga tagtgaaatc agacaaatct
    16441 tcccccatta aagttttaag taaggttgat ttaccatttc cttcttcgcc aataatagct
    16501 accttttccc cgtcttggat ggtcatggtt aggtcagaga caaggtctcg taaatctttg
    16561 ttttgtgtga tggtcaggtg attgattttt atcatactat tgccctttct agaatgtcga
    16621 tagtacataa caaaaagctc tactttacct agtagagccc aaagtctatg tcaaaaaaac
    16681 tctattaaca tgccagaaaa agagcataaa agagcacaca aaaagagaca aaaacaagat
    16741 ctactaaata aaggttcttt atttgataga cttagttgtt catgtctccc ttacctccga
    16801 gtattagtat ctttatacta tacttttaag gaaattttgt caacagaaaa ctggaaattc
    16861 tatgctctaa aatccaaaaa caggtccata gagacttagt acgtgtttga catgctcgta
    16921 atggatttta tcatagtttc gccaagcagt gcgtgcttga tcgtttagtt ttaggctacc
    16981 cagtccaatc agaggactgg tgggttggta aaatttctca agatcaatta agatactgtt
    17041 gttcaacttt tccgtttttt tgagctcttg catagtagtg tttagcagct cttgtagtcg
    17101 aatatcatct gccgtaccct gtttacagtt ttggtagctt ttatttaact tggataggag
    17161 ttgaatgagt ttcttgtctt ccatgtcttc catatgagca tcctccttga tctgatgtac
    17221 tctttcccta tagtatagca ctaaaaaata aaactgtcat agtaaatatg ttaaaatttt
    17281 gaattttaat tacaaagttt ggtgtgctga tttgtagcct tttcatggta taatcaagag
    17341 agtaaatctt tatggaggaa gtatgaaatt aaatattcaa gaaattcgta agcagtctga
    17401 aggtttgaac tttgaacaaa cgttagattt agttgatgat ctgcgtgcac gtaatcaaga
    17461 aattttagat gtaaaagata tccttgcagt tgggaaagta caatatgaag accgtatgta
    17521 tttcttagat tatcaactat cttataccat tgttcttgct tcgagtcgca gtatggagcc
    17581 agttgagtta gttgaatctt atccagtcac ggaagttttc atggaaggcg caactaacca
    17641 gctagatcaa gaagttttag atgatgactt ggtcttgccc atcgaaaatg gggagcttga
    17701 ccttgctgag agtgtatcag acaatatcct gctaaacatt cctatcaagg tcttgacggc
    17761 tgaagaagaa gctggtcaag gatttatctc aggaaatgac tggcaaatca tgacagagga
    17821 agaataccaa gctcaaaaag cagtaaagaa agaagaaaac agtccttttg ctggcttaca
    17881 aggactattt gacggagatg aataatggtc ttgtcaaaaa aacgagcacg aaaggtgcta
    17941 gaagaaatca ttgccctctt cccagatgcc aagcctagtc ttgattttac caatcatttt
    18001 gaactcctgg ttgcggtcat gttatcagcc cagacgacag atgcagcggt aaataaggcc
    18061 acaccaggtc tctttgttgc ctttccaaca ccccaagcta tgtctgtagc gacagagagt
    18121 gagattgctt cacatatttc tcgcttggga ttgtatcgga ataaagctaa attccttaaa
    18181 aaatgtgccc aacagttact agacgatttt gatggtcaag tccctcagac acgtgaagaa
    18241 ttggagagtt tggcaggtgt tggtcgcaag acagccaatg ttgtcatgag tgtaggattt
    18301 gggattccag cctttgcagt ggatactcat gtggagcgta tttgcaaaca ccacgatatt
    18361 gtcaaaaaat cagcgacgcc acttgaggtg gaaaagcggg tcatggatat cttgccgcct
    18421 gagcagtggt tagctgccca tcaggccatg atttattttg gaagagccat ttgccatcca
    18481 aaaaatccag agtgtgacca gtacccacaa ttatatgatt ttagcaattt gtaagatact
    18541 acattgaaac tttttgcttg attttaagca tgctttgtgc tatagtaaat gataactaaa
    18601 tattccttta aacctgtccc gtgaggcagg caaggagcgc gataaagtag aagggtgaag
    18661 tctatactgt gtgcagtagg gctcgcttgg ctataaattt caagtctcct tgtttaagga
    18721 gacttttctt tttggaggtt tgtcatgaaa acaaaagaag ttgtagacga attgaccgtc
    18781 aaacgagcga ttacgcgtat tacttatgag attatcgaac gcaacaaaga tttgaataag
    18841 atcgtcttgg ctggtattaa aactcgtggt gtctttattg cccaccgaat ccaagaacgt
    18901 ttgaagcagt tagaaaatct ttcagttcct gttgtggaat tggatactaa acctttccgt
    18961 gatgatgtta aaagtggaga agatacttct ttggtttctg tcgatgtgac agaccgcgaa
    19021 gttatcttgg tggatgatgt gctctataca ggtcgtacca tccgtgctgc tattgataat
    19081 attgtcggtc atggtcgtcc tgcgcgtgtg agtttagcag ttctagtcga tcgtggacat
    19141 agagaattgc caatccgtcc agattacgtt ggaaaaaata tcccaaccag tcgttctgaa
    19201 gaaatcatcg tagagatgac agaacttgat gaccaagaca gagttctgat tactgaagaa
    19261 gcttagaaag ttaaaggagt agccatgtca gaaaatcaac aagcattgaa ccatgtggtg
    19321 tccatggaag acctcactgt cgatcaagta atgaaattga ttaagcgagg aattgagttt
    19381 aaaaatggag cccagcttcc ctatgaagac catccgattg tttccaatct cttctttgag
    19441 gattctacac ggacacataa gtcctttgaa gtcgcagaga ttaaacttgg attggaacga
    19501 cttgactttg atgtgaagac tagctcggtt aataagggtg agacacttta tgacaccatt
    19561 ttgactctgt ctgctttagg agtggatgtc tgtgtgattc gccatccaga ggtcgactac
    19621 tatagagaat tgattgctag tccaacgatt acgacttcca tcatcaatgg tggagatggt
    19681 tcgggccaac accctagcca gagcttgctt gatttgatga ccatttatga ggaatttggc
    19741 cactttgagg gtcttaaagt tgctattgca ggtgacttgg accactcacg cgttgccaaa
    19801 tccaatatgc agattttgaa acgcttggga tctgaactct ttttcgctgg acctgaggaa
    19861 tggagaagtc aagagtttgc agactatgga aagtttgtaa ccattgatga aatcattgat
    19921 caggttgatg tcatgatgtt tctccgtgtg caacacgaac gccatgatag tggagctgta
    19981 ttttcaaaag aagactacca tgcccaacat ggcttgactc aagaacgtta cgatcgtttg
    20041 aaagaaacag caatcctcat gcacccagct ccaatcaatc gtgatgtaga aatagcagac
    20101 cacttggttg aagcaccaaa atcacggatt gtccaacaaa tgaccaatgg tgtctttgtt
    20161 cgaatggcaa tcttagaatc cgtactagcg agtagaaacg ccaactaaaa cacaagacgt
    20221 taaaagacgc cagtgagcgt ccacgagagg tgaaaatatg acaaaaagaa ttctagtatt
    20281 agaagatggc acagtttttg aaggcaaggc cttcggagca gatattgatg taacaggcga
    20341 aatcgtcttt aatacaggga tgaccggcta ccaagaatcc attacagacc agtcttataa
    20401 tggacaaatc ttgaccttta cttatccttt ggtaggaaat tatggtatta atcgtgatga
    20461 ttatgaatcc attattccaa cttgtaaggg agtcgttgtt tttgaagaag cgcgtagagc
    20521 tagcaactgg cgcaaccaaa tgaccttgga tgaatttttg aaagccaaga aaattccagg
    20581 gatttcagga attgatacgc gtgctcttac caagattatc cgtaagcatg gtactatgcg
    20641 tgcaaccttg acccatgttg gggacagtat ggaccatgtg acggaccagc tccaagcaac
    20701 agttttaccg acagacaata tcaaacaggt ttctactaaa acgtcttatc cagctccagg
    20761 agttggtttg agcgtggtgc tagtggactt tggtctcaag cactcaatcc tacgtgaact
    20821 ttctaaacgc aactgtaacg tgacagttgt tccttattcg acaacggctg aagaaattct
    20881 ccatctcaat cctgacggag ttatgttgtc aaatggtcca ggtaacccag aagacgttcc
    20941 acaagcactc gacatgattc gcggtgtaca aggaaaaatt ccaatctttg gtatttgtat
    21001 gggacaccaa ctctttgcaa tggcaaacgg ggctaagacc tataagatga agtttggcca
    21061 ccgtggattc aaccatgcgg tacgtgaaat cgcaacagga cgagtagact tcaccagcca
    21121 gaaccatggt tatgcagtca gccgcgagga tttgccagag cacttgatta ttacccacga
    21181 agaaatcaat gacaagtcag tggaaggtgt gcgccacaga taccaacctg ctttctctgt
    21241 tcaataccac ccagatgcag ctcctgggcc acacgacgct agctacctat ttgacgagtt
    21301 tatcgagatg atggaagttt ttaaacaatc aaactaagaa cgagtaaaag ctcgtcggag
    21361 aatttatgta actgaacacg gacggaaagc tcagaatgta gagaaaccaa cttggattgt
    21421 caatccttcc ttgatttcct aaaattcaat cgctttctat tcgtcctttg tatcttattt
    21481 aatgtcgccc tgagaggcga cgaatagaaa ggagaagggt gctccgtatt tgctgaactg
    21541 aatacgggct acggacggtg ctaaaaagat agttattcct agaactgaca gttcttcgtc
    21601 ataactccta ttttagcttt gtccgcttga cacccttaat atcttatata tgcctaaacg
    21661 tactgatatt caaaaaatta tggtgattgg ttctggtccg attattattg gtcaggctgc
    21721 tgagtttgac tacgctggga ctcaggcttg cttgtcgttg aaagaggaag gttatgaggt
    21781 tgttttggtt aactcaaatc ctgcaaccat catgacggac aaggaaattg ctgacaaggt
    21841 ttacattgaa ccgattacac ttgagtttgt gacacgtatt cttcgtaagg aaggtccaga
    21901 tgccttgcta ccaacactcg gtggtcagac aggtctcaac atggccatgg aattatctaa
    21961 aaatggtatc ctagacgagc ttggcgttga acttctgggt accaaattat ctgccattga
    22021 ccaagcggag gaccgtgacc tctttaaaca attgatggaa gagcttgaac aacccattcc
    22081 agaatctgaa attgttaaca cagtagaaga agcagttgcc tttgcagcga caattggcta
    22141 cccagtcatc gttcgtccag cctttaccct tggtggtact ggtggtggta tgtgtgccaa
    22201 cgagaaagaa ttgcgtgaaa tcactgaaaa tggtttgaaa ttgtcacctg ttacccaatg
    22261 tttgattgag cgttcgattg ccggtttcaa ggaaattgaa tacgaagtga tgcgtgactc
    22321 agctgacaat gccttggttg tttgtaacat ggaaaacttt gacccagttg ggattcacac
    22381 aggggattcc attgtatttg cccctgcgca aaccatgtca gactatgaaa accaaatgct
    22441 tcgtgatgcg agcttgagca ttattcgtgc cctcaagatt gaaggtggat gtaatgttca
    22501 gctagctctt gatcctaaca gcttcaagta ttatgttatc gaagtaaacc ctcgtgtatc
    22561 acgttcgtca gcccttgctt ctaaagcgac aggatatccg attgctaagt tggctgccaa
    22621 gattgcagta ggtttgacct tggatgaggt tataaaccca gttacaggtt caacctatgc
    22681 catgtttgaa ccagcccttg actacgtagt tgctaagatt ccacgtttcc catttgacaa
    22741 gtttgaaaag ggtgaacgcc gtctcggtac acaaatgaag gcgactggag aagtcatggc
    22801 aattggtcgt aacatcgagg aatctcttct caaggcctgc cgctcccttg aaattggggt
    22861 gcaccacaat gaaatacctg aacttgcagc agtttctgat gatgccttga ttgaaaaggt
    22921 tgtcaaagcc caagatgacc gtctcttcta cgtatcagaa gccattcgtc gtggctacac
    22981 acctgaagaa attgcagagc ttacaaaaat tgatatcttc tatcttgata aactcttgca
    23041 tatctttgaa attgagcaag aattgggtgc tcatccacaa gatttagaag ttttgaaaac
    23101 agccaaactt aatggttttt cagaccgtaa gattgctgaa ctctggggaa cgactgatga
    23161 taaagttcgc caacttcgct tggaaaacaa gattgttcca gtttataaga tggtagacac
    23221 ttgtgcggca gagttcgact ccgaaacgcc atatttctat tcaacctatg gttgggaaaa
    23281 tgaatctatc agatctgata aagaatctgt acttgtccta ggttcaggtc caatccgtat
    23341 cggtcaaggg gttgagtttg actacgcaac cgttcactct gttaaggcta tccaggcagc
    23401 tggttatgaa gctatcatca tgaactcaaa cccagagacc gtttcaacag acttctctgt
    23461 atcagataag ctttactttg agccattgac attcgaagat gttatgaacg tcattgactt
    23521 ggaacaacca aagggagtta tcgttcagtt cggtggtcaa acagccatca accttgcgga
    23581 gccattggca aaagcaggtg tgaccatcct tggtacacag gttgctgacc tagatcgtgc
    23641 cgaagaccgt gacctcttcg agcaagctct caaagaattg gatattccac agccaccagg
    23701 acaaacggct accaatgaag aagaagcagc tcttgcagct cgcaagattg gcttcccagt
    23761 tcttgtccgc ccatcttatg tacttggtgg acgtgccatg gaaatcgttg aaaacgaaga
    23821 agaccttcgt tcttacatgc gaactgctgt taaggctagt ccagaccacc cagttcttgt
    23881 cgactcttat atcgttgggc aagagtgcga agttgatgcc atttcagatg gtaaaaatgt
    23941 actcattcct ggtatcatgg agcatatcga acgtgctggt gtccactcag gtgactcaat
    24001 ggctgtttac ccaccacaaa ccttgtcgca aaaggttcag gagaccatcg cagactacac
    24061 caaacgctta gcaatcggtc ttcactgcct tggaatgatg aacatccagt ttgttatcaa
    24121 ggatgaaaaa gtctacgtta ttgaggtcaa tccacgtgcc agccgtactg ttccattcct
    24181 atctaaggta accaatattc ctatggctca agtagcgacc aaactcattc ttggtcaaag
    24241 tttatcagaa cttggctacc aaaatggact ttaccctgaa agcacccgtg ttcatatcaa
    24301 ggcacctgtc ttctccttta ccaaactagc taaggtagac agcttgctcg gtcctgaaat
    24361 gaagtcaaca ggtgaagtta tgggttctga tgctactttg gaaaaagctc tctataaagc
    24421 ctttgaagct tcttatctac acttgccaac ttttggtaat gtcgtcttta ccatcgctga
    24481 tgatgccaaa gaagaagcct tgaacttggc tcgtcgtttc caaaacattg gttatggaat
    24541 ccttgcgaca gaagggacag cagccttctt tgctagtcat ggcttgcaag cccaacctgt
    24601 tggtaagatt ggtgatgacg ataaggatat cccaagtttt gtacgcaaag gaagaattca
    24661 agctatcatt aacacagtag gaacaaaacg aactgctgac gaagatggtg agcaaattcg
    24721 tcgttcagcc attgaacacg gggtgcccct cttcacagcg ctagatacag ctaatgccat
    24781 gcttaaggta cttgaaagtc gtagctttgt tacagaagcg atttaaatag aaaaataaga
    24841 tatagcagac tgaatttaga acagtacaca ggaatactaa aatatttcta taaattaatt
    24901 tgaattttct aattgatttg ttcgcatctt atttcaatct actatagaaa aaagtcttta
    24961 aaattataaa acgcatcata tcaagatttt tcaaaaacct tgatatgatg cgttttattg
    25021 tgggaatatg tatttcattt tctactaaaa ttatgttttt gaataacctc tatcttagta
    25081 gtttgtataa tccccctcaa tcagtttttg cgataagctt taatgctatg actataccac
    25141 tcttgcattt cttttgatgg tggtgttata taatcgccat acatctgggt taaaaattgg
    25201 tcatattttt tgggaacagg caacatacgg ccctcaaact cagttaaaat cagttcttta
    25261 aaggtatcaa ctgggaagat ttctttcatc ccttccttac cgatcccaac tcctccttca
    25321 tattgaggag tgttggttac agcatttttg actagttgat caattttctt gtaaaagtag
    25381 cgaggattga caaatcggag agcgtaccag ctacataatc taagaaaatc ttttagtttg
    25441 ctatcaccgt gaactgctcg tgattttttg atataagcta gttgacgaag agccacatac
    25501 ttatagctct tgtcgacaat gctcaagtct gtaaatcgat caattgggaa gacatcgatg
    25561 aaaaggctgg tatcatgacg cttgtactta acatggtctt ctataacagt agaagtgtcc
    25621 aaaatcgatg cgaaattatg gaagtaccaa gaagatgtat cgtaggaaag aaccttgtag
    25681 cgagggtgat tttcttcttc aataatcttc agtaaacgct cataatcctc acgataaagg
    25741 gaaatatcaa tatcatcatc ccaaggaatc atacctttgt ggcggatggc tccaagcatg
    25801 gttccataac tgagaaaata aggaatatca tatttcttac aagtctcatc aatatagtcc
    25861 agcagggcta gttgaatttc tttaatttct tttttttcta aatattgcat cctaatcctc
    25921 caatttataa gcgtgaaatt catgactgta gaagcgtttt tcttctggtg gtagggtcat
    25981 ataatctcca taaaattgtg tcaaaatagt atcaaatttt tcaggtgcag gaaggcttaa
    26041 attctcaaag ggtaaatcga ttgttttatc aaaggtacca cttgggaaga cttccttttc
    26101 cttaaatttt gaagggataa aagccatata ttgcccattt tcacgactat atttttgaat
    26161 ttctttctcg attttatttg caaaataacg aggagaaacc ggtcgaagga gtaaccagaa
    26221 ggctgttcgt atccaatctt ttaaaaggct atccttatag acaatatttt tatgtttact
    26281 gaaagacagc agtttgaagc tttccagttt ataacaagta tcaatgacct taggatcatc
    26341 aaagcgatct atagggaaaa tatcgataaa gataccagac tcataggttt ttgtatttcg
    26401 agtatcaata attttagtcg tactgtcggt tatcttgata aagttgttaa agtagttctt
    26461 atcagtttct aaggatagga gcttatactt gcttttttcc ttttgaaaaa tgttaataaa
    26521 tcgttggtag tcttctctag gcatggataa atcaatatcg tcgtcccaag ggataaagcc
    26581 ctcatgtcga accgccccaa tcagagtacc gtagttaata atatagttga tattgtgctt
    26641 tttacagaga gtatcaatat aatccaaaat ttctaattca atttgtttgg catcttcaat
    26701 ggttagttgt ttcattttaa actcctatga ttttttgaat ttatttttta aggctaggac
    26761 atggtttaaa aattcataga aaatgctatc ttttgtgaag acaagtagac taatataaga
    26821 gatagctgat agcaagacaa tcaaaccagt attaattaaa aatggcaaat taatgaccat
    26881 atccacagga tacacgaaat taatcaggaa ataaattgct acaaaggaaa gtgaaaagag
    26941 agagtatcga acagtatagc taaagatatg tcccaagtgg atgagttgtt ttctatggat
    27001 gaaaataata tagaaaacaa gtagagaagt ctctgataac atagttgtca gtaagtagta
    27061 ttcaggaacc acgatatggt tgaaaaagag gagactattc aagcccaaat tgagtagccc
    27121 agcaaagact gtatagactg tgatacgttt ttcatagcca ttggtaaaga gaatttggga
    27181 accaagaatg gtatctaagg ccaggataat cgtacgaaaa gcgaagagag aggtcaagat
    27241 gccgcctccg atatattttt cactaccgta aagtaggatg gcatttggtc ctaaaaccat
    27301 gagtccaaaa ctcagtggaa tgataaagaa gttaaagatt cgactacctc tattaaccag
    27361 agaaacatag gcttctttgt ctcctttccc cagatagtaa ctgagacgag gcacactcac
    27421 tccaattgca cctgttacaa ccccagctat aacggtcaca attcgctgag ctatggtata
    27481 gtaactaacg ttgacatcaa tccctgtttt aacgaggaag aggcgatcta aaaaagtgaa
    27541 gagcatattg gcattggcaa agactaacat ggctgtcaga gggagaaaga gtggtttaaa
    27601 atcacttagg tgaatcttaa caagtttgat gtctctttta atccaaaaat aactaatcag
    27661 gtagttaatc agcgtcgata aactcatcac aagtgtatag acaacaatat cgtgttcatt
    27721 tttaacaaat aagaaaatag agaccagcat caggatacgg atgaaggcag ttttgtaaaa
    27781 gagaaaactg taattttcca gagcttcatt gacccattcg attgaaaaaa tctgggcaat
    27841 gagttgaatc cccataacaa ggtagacctt tttgacgatt ggattatcaa taaagaagag
    27901 aggataggct aggatataga cagcagtggt caaaatcgta caagcgatgc acaaataaaa
    27961 aagactagaa aaggttctgt taagatcttt tttgttatcc ttgacattac tgatagccct
    28021 taaaccgtag ttatagacac cataagttgc aaagggcaag aaaaatgaca aaatagtgtc
    28081 gactgagttg aagtaaccat agtcagttcg gtccaagaca cgcgcgacat aggttccagt
    28141 taggatggga aaaataatat tcaagacacg aattcccatg taagatagag catttaattt
    28201 tatacttttc attcaattta cctcgttttt cattatatca taaagttagc taataagaaa
    28261 tgaagggcag taagtcaagt aatcactttg aagtttcaaa tcttaagttt taagttttct
    28321 ttaaggaaag tatattattc tgaaggactc taaaatttcg cagccattta ttagtaattg
    28381 ctacagaatt cctagtcatt actagaaatg gactagtttc tttgaataat agaactgcat
    28441 aattctccta ttctagaagg ggaggaccag tatttctttt atgataggac tagattgtgg
    28501 tataatagag agaataagtt tttttagtaa gacaaaggag aaaatagatg atttatgcag
    28561 gaattcttgc cggtggaact ggcacacgca tggggatcag taacttgcca aaacaatttt
    28621 tagagctagg tgatcgacct attttgattc atacaattga aaaatttgtc ttggagccaa
    28681 gtattgaaaa aattgtagtt ggtgttcatg gagactgggt ttctcatgca gaagatcttg
    28741 tagataaata tcttcctctt tataaggaac gtatcatcat tacaaagggt ggtgctgacc
    28801 gcaatacaag tattaagaaa atcattgaag ccattgatgc ttatcgtccg cttactccag
    28861 aggatatcgt tgttacccac gattctgttc gtccatttat tacacttcgc atgattcagg
    28921 acaatatcca acttgcccaa aatcatgacg cagtggacac agtggtagaa gcagttgata
    28981 ctatcgttga aagtaccaat ggtcaattta ttacagatat tccaaatcgt gctcaccttt
    29041 atcaaggaca aacacctcaa acattccgtt gcaaggactt catggacctt tatggatctc
    29101 tttctgatga agagaaggaa atcttgacag atgcatgtaa aatctttgtg atcaaaggaa
    29161 aagatgtggc cttggccaaa ggtgaatact caaatctgaa gattacaacc gtaacagatt
    29221 tgaagattgc aaaaagtatg attgagaaag actagtaaaa tgattaatca aatttatcaa
    29281 ctaactaagc ctaagtttat caatgtcaaa tatcaggaag aggctattga ccaagagaat
    29341 catatcctta tccgtcccaa ctacatggct gtctgtcatg cggatcagcg ttactatcag
    29401 ggaaaacgtg atcccaagat tttgaataaa aagcttccaa tggcaatgat tcacgagtca
    29461 tgtggaaccg tcatttctga cccgaccgga acctacgagg ttggtcaaaa agttgtcatg
    29521 attcccaatc agtctcctat gcagagtgat gaagaattct atgaaaacta catgacaggg
    29581 acccatttct tgtctagtgg atttgatggc tttatgagag agtttgtttc tctccctaaa
    29641 gatcgtgtgg tggcttatga tgctattgaa gatacggttg cagccattac agagtttgtc
    29701 agtgtgggca tgcacgctat gaatcgtcta ttgactcttg ctcatagcaa gcgggagcgg
    29761 atcgccgtta ttggagatgg aagtttagct tttgtggttg ccaatattat caactatact
    29821 ttgccagaat cagagattgt ggttattggt cgtcattggg aaaagttgga actcttctca
    29881 tttgccaaag aatgctatat tacggataat attcctgaag agttggcctt tgaccatgct
    29941 tttgaatgtt gtggtggtga tggtactgga ccagctatta atgacttgat tcgctacatt
    30001 cgtcctcagg gaacgattct catgatggga gttagcgaat ataaagtcaa tctcaatact
    30061 cgcgatgcct tagaaaaggg cttgattttg gttgggtcat ctcgttctgg tcgcattgat
    30121 tttaaaaatg ctatccaaat gatggaagtc aagaaatttg ccaatcgtct taaaaatatc
    30181 ctttatctag aagaacctgt aagagaaatt aaagatattc atcgtgtctt tgcaaccgat
    30241 ttaaacacag cctttaaaac agtgtttaag tgggaagtat aagtactgga ggttaattgt
    30301 ggagaaaatc attaaagaaa aaatttcttc cttacttagt caagaagagg aagtcctcag
    30361 tgttgaacaa ctgggtggaa tgaccaatca aaactatttg gccaaaacaa caaataagca
    30421 atacattgtt aaattctttg gtaaagggac agaaaagctt atcaatcgac aagatgaaaa
    30481 gtacaatctt gaactactaa aggatttagg cttagatgta aaaaattatc tttttgatat
    30541 tgaagctggt atcaaagtaa atgagtatat cgaatctgcg attacgcttg attcaacgtc
    30601 aatcaagacc aagttcgaca aaattgctcc aatattacaa actattcata cgtctgctaa
    30661 ggaattaaga ggagaatttg ctccttttga agaaatcaaa aaatacgaat ccttgattga
    30721 agaacaaatt ccttatgcca actatgaatc tgttagaaat gcagtcttct ccttagagaa
    30781 aagactggct gacttaggtg ttgacagaaa atcttgtcat atcgatttgg tgcctgaaaa
    30841 ctttatcgaa tcacctcaag gacgacttta tttgattgac tgggaatatt catcaatgaa
    30901 tgatccaatg tgggatttgg ctgccctctt tttagagtct gaattcactt cccaagagga
    30961 agaaactttc ttatctcact atgagagtga ccaaacaccg gtttctcatg aaaagattgc
    31021 tatttataaa attttacaag atactatttg gagtctatgg actgtctata aggaagagca
    31081 aggtgaagat tttggtgact atggtgtgaa tcgttaccaa agagctgtta aaggtttggc
    31141 ttcttatgga ggttcagatg aaaagtaaaa acggagttcc ttttggcctt ctctcaggta
    31201 ttttctgggg cttgggtcta acggttagtg cttatatctt ttcgattttt acagatttgt
    31261 caccctttgt ggtggctgca gctcatgatt ttttgagcat ctttatctta ctagcttttc
    31321 tcttggtaaa agaagggaaa gttcgcctct caattttctt aaatattcgc aatgtcagtg
    31381 ttatcatcgg agccttgcta gcaggcccta tcggtatgca ggccaatctt tatgcagtta
    31441 agtatatcgg aagttcttta gcttcatctg tatcggctat ttaccctgcg atttcagttc
    31501 tattggcttt cttctttttg aagcacaaga tttcgaaaaa tactgtattt gggattgtct
    31561 tgattattgg agggattatt gcccagacct ataaggttga acaggttaat tccttctaca
    31621 ttgggattct ctgtgctttg gtttgtgcta ttgcatgggg aagtgagagt gttcttagct
    31681 cctttgctat ggaaagtgaa ctgagtgaaa tcgaagccct cttaatccgt caagtgactt
    31741 cgttcttgtc ctatcttgtg attgtgctct tctctcatca gtcatttact gcagtagcca
    31801 atggacaatt gctaggtctc atgattgttt ttgcagcctt tgatatgatt tcctacttgg
    31861 cttattatat cgctatcaat cgcttgcaac cagccaaggc tacaggcttg aacgtgagct
    31921 atgtagtatg gacggtcttg tttgcagttg tttttttggg tgcaccgcta gatatgctga
    31981 ccattatgac gtcacttgtc gtcattgctg gagtttatat tattattaaa gaataaagga
    32041 gattcgtgtg aaagccatta tcttagcagc gggattggga actcgcttgc gtcctatgac
    32101 tgaaaatacc cctaaagcct tggttcaggt taatcaaaaa cctttgattg aataccaaat
    32161 tgagtttctc aaagaaaaag gaatcaatga catcatcatc attgttggtt atcttaaaga
    32221 acaattcgat tacttaaaag aaaaatacgg tgttcgcctc gttttcaatg ataaatacgc
    32281 tgactacaat aacttttact ctctctatct tgtaaaagaa gaattggcca acagctatgt
    32341 tattgatgct gacaattatc tctttaaaaa tatgttccgc aatgatttga cacgttcgac
    32401 ttattttagt gtttatcgtg aagattgtac caacgaatgg ttcttggtct atggagatga
    32461 ctacaaggtt caagacatta ttgttgatag caaggcaggt cgcatcctta gtggtgtatc
    32521 cttctgggat gctccaactg cagaaaagat tgtcagcttt atcgacaagg cttatgcaag
    32581 tggtgaattt gttgatctct attgggacaa tatggttaag gataatatca aagagctaga
    32641 tgtctatgtt gaagaattag aaggcaatag catttatgag atcgatagtg tccaagacta
    32701 tcgtaaatta gaagaaattc ttaaaaacga aaattaaaga ttccaacatc tgacaaaata
    32761 gtcggatgtt ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa
    32821 atggagttat ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg
    32881 accaatcaac agattttgaa agtgctagaa tacggtgaaa atgttgatca ggagcttttg
    32941 ttgggtgata ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat
    33001 tttcagatag acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt
    33061 ttagatgact gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt
    33121 tacaagggaa atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct
    33181 tgtagcaaac agggagctaa gtcagttgaa aaagtcattc aaggcttgga aaatgaactg
    33241 gttattgtca gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag
    33301 aatggcggaa aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc
    33361 aataaacgct tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct
    33421 ggcgaacaac ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt
    33481 cgtggtgtga ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga
    33541 gcaatggaag aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca
    33601 gacggttgcc atcatttgat tcaagaagga gcaaaattgc tcaccagtgg gcaagatgtt
    33661 cttgcggaat ttgaatttta aaaatgacct aagctagaat tctaagaaaa aatcaatttt
    33721 aagagaaaat gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt
    33781 gctaatatgc gttttttcta agtggattag tagagtagag gatttttctc atataatact
    33841 cttcgaaaat ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga
    33901 gctgagttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag
    33961 cttcctagtt tgcgctttga ttttcgttga gtataaggga aagtatagtg aattgaaata
    34021 agatgtgaac aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa
    34081 ggtgcactgt tatagattca atacactata atttagtgta attgagaaag gagaaatgat
    34141 tgtgattgat gttggctagg ttatgttcaa tgattcctac catctcaaat cttgttagta
    34201 aggaaaaata aattcttcaa aagtagagat tacaaggctt gtttaagaaa gaattcaaag
    34261 accttgacaa ataaaaataa aatggttatt ataaaaaatg gtctgaaata gatgatgata
    34321 cttttcgaaa atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac
    34381 ggttagcttc cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta
    34441 gacatttgag tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca
    34501 gactactaaa gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat
    34561 atttgtgaca aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga
    34621 attagaactt tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat
    34681 cggattaaat atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat
    34741 gacacctatt ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa
    34801 atcttttaaa atattagcta ttcaaattct tgccagttta atagcttcaa cactttattt
    34861 ttatctttct cccatttcgt atgctagttc ggaaattgtt gctagaacct ctccgactat
    34921 ttgggatgtt ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa
    34981 agagaccaat aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg
    35041 tacagtaggt tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct
    35101 attcctcatc aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat
    35161 ggttaagaaa cattatttta aagataatga agaagactct aaaatgcgta ggattttgct
    35221 tctagttgct gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga
    35281 aacgttgaaa aaagagtccc ttaagaaatt tatatcagag cagtttcagg ggtataatat
    35341 tttgaaaaaa acctattcta aaaagactca taccctaaag ctaaccattt caggaaatta
    35401 tttgacagaa gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga
    35461 tgtttctgtt caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt
    35521 ggagcatttc ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagccaataa
    35581 atttgataca gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt
    35641 cttctatgta tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag
    35701 tagctaagtc ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga
    35761 aaaggtgtga tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc
    35821 tagtcatcgt ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact
    35881 acaaggtttt agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg
    35941 atattgaaaa taattatgaa ccgcaatata ttaatatccg aggaaaaggc cctcttatca
    36001 atgacttgaa aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc
    36061 gtgaaggaga agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg
    36121 ccaaccgtgt ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac
    36181 ctcgtaagat cgatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct
    36241 tggtagggta ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag
    36301 gtcgcgttca gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct
    36361 tccagccaga agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc
    36421 atgcttcctt ctatggagta gatggtaaaa agatgaaact gaccagcaat gacgaagtca
    36481 aggaagtctt gtctcgtctg actagtaaag acttttcagt agatcaggtg gataagaaag
    36541 agcgcaagcg caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca
    36601 ataaaatcaa tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa
    36661 ttaatatcgg ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta
    36721 tcagtcctgt agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagtaagt
    36781 attctaagca cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta
    36841 ttcgtccgtc aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc
    36901 agctcaagct atataccctt atctggaatc gttttgtggc tagccagatg acagcggccg
    36961 tttttgatac catggctgtt aaattgtctc aaaaaggggt tcaatttgct gccaatggta
    37021 gtcaggttaa gtttgatggt tatcttgcca tttataatga ttctgacaag aataagatgt
    37081 taccggacat ggttgttgga gatgtggtca aacaggtcaa tagcaaacca gagcaacatt
    37141 tcacccaacc gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg
    37201 gggttggacg tccatcaacc tacgcgccaa ccattgaaac cattcagaaa cgttattatg
    37261 ttcgcctggc agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca
    37321 tcgttgaata tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac
    37381 tggatgatgt cgaagttgga aaagagcagt ggcgacgggt cattgatgcc ttttacaaac
    37441 cattctctaa agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg
    37501 aaccagctgg atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt
    37561 ttggtaaatt ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga
    37621 aagagattgg tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca
    37681 agcgtaatcg cctattctat ggttgcaatc gctatccaga atgtgaattt acctcttggg
    37741 acaagcctgt tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc
    37801 gtggtggtgg caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat
    37861 aagaggaggg gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca
    37921 tcattttatg cgaaactaga agaagattat tttatactca atgagaatca aagagcaaat
    37981 tagaaagcta gtcgcaggtt gctcaaagca ctactttgag gttgaagatg gaagctgacc
    38041 tggtttgaag agattttcga agagtattaa ctaggagaag ttatgcgtct tatctatcta
    38101 attattggtt ttttatcgct ggccttggct attgttgggg ttgttttacc cttgttgccg
    38161 acaacgcctt tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa
    38221 gactggcttt atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag
    38281 tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt
    38341 tctatttatt ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt
    38401 atcacttatt atctcttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt
    38461 gccttgataa aattgaaagc atattcataa caatatgata taataaattt gaagtaatat
    38521 tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag
    38581 cgatgcaggc tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa
    38641 cacccagcta tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca
    38701 tcatgaccat gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta
    38761 tcatgctaga agacatttgt ttgactgctc aggctggaag tcaaggggtt gtatttggag
    38821 ctttaactgc tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa
    38881 aaggaatgga aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg
    38941 aagctattga ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt
    39001 ctggcgactc cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag
    39061 gtaaaattga aattctacca ggtgggggga ttgaccttga caaccgtcaa acctttattg
    39121 accaggtggg ggtaacacaa ttgcatggca ctaaggttgt tttttaaaaa atagaaagga
    39181 actgctagcc ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt
    39241 aatcaagaaa aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt
    39301 tgccagattt tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac
    39361 tttcaagtct ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg
    39421 aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg
    39481 aaggcttgtt ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa
    39541 gttcaggaaa agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct
    39601 gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat
    39661 aagctggaaa agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta
    39721 gctaatttgc tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg
    39781 attagtgtgt cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa
    39841 agttggaact taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta
    39901 gctaaatatt ctttactgaa gaaattttca gaaaatatag gatttaccac accagaggaa
    39961 tgtggtgcca tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat
    40021 tcgcctcact gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag
    40081 aatggtgcag gacgtgttga agggactatc aatggtatta gggagcgagc tgaaaatgct
    40141 gctttggaag aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc
    40201 agtattgtcc taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt
    40261 ccagttccta aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt
    40321 caccaagatg gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt
    40381 ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga
    40441 gaattggccc tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca
    40501 ctggccgata agaagtaaga aatcacagat gcagatactc gagctttggt agctggaacc
    40561 atggttgaaa atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat
    40621 aatgacattg aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat
    40681 gcgacagggc aaggttccgt tgaagcaatc tttaacgcta tcgataagtt ctttaactaa
    40741 tctgttcgtt tggtgtccta cactatcaat gcggtaacag atggaatcga tgcccaggat
    40801 cgggttttgg tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt
    40861 gattttgatg tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa
    40921 aaagagaatg caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa
    40981 aggagaaggc tatggcaaag aaaatagtag ctctagtagg agacggaatt ggcccagaaa
    41041 tcatggaggc tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg
    41101 agattgacag acgaccgttc ggaggtgcag atattgatgc agcaggacct cccttacctg
    41161 atgaaaccct taaggcaagt agggaagcag atgctatcct actagcagct atcggtagtc
    41221 ctcagtatga tggagcagcg gttcgccctg aacaaggcct gatggctctc cgtaaggaac
    41281 tcaatcttta cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac
    41341 cactcaaacc ggaacgaatt tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg
    41401 agatttactt tggagatcat attcttgaag agcgcaaagc gcgtgatatc aacgactata
    41461 gctatgagga agtggagtgg attattcgca aagcctttga aattgcaaga aatcgcagaa
    41521 aaatccttac tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag
    41581 tagctgagga agtcgcacag gatttctcag atgtaacctt ggaacaccag ctggtagact
    41641 cagctgctat gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc
    41701 tttttggaga tattttatct gatgaatcaa gcgtcttatc tggtacactt ggggttatgc
    41761 catcagccag tcattctgaa aatggaccaa gtctctatga acctatttac ggttcagcac
    41821 ctgatattgc aggtcaagga attgccaatc ctatttccat gattttatca gttgccatga
    41881 tgttgagaga tagtttcgga cgttatgagg atgcagagcg tatcaaacgt gctgttgaga
    41941 caagtctggc ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa
    42001 tgacggaagc tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt
    42061 gatttggaat gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag
    42121 agcttggcgc atccaagaga aaatcttact cattttagcc cttacttgtg gtggttttgg
    42181 ggcctggtta gctggaatca cttttcacca caagactcga aaatggtact ttaaaacagt
    42241 ttggtttctt gggatggtga ccacactagt agccttatat tttatttgga ggtaatggat
    42301 ggcagggtct tcgagggaat acgctgcttg ggctctagcg gactatggtt ttaaggtcgt
    42361 gattgcagga tctttcggtg acattcatta caataatgaa ctcaataatg gcatgttgcc
    42421 aatcgttcag cctagagagg ttagagagaa actagcccag ctaaaaccaa ccgaccaggt
    42481 aactgtggac ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat
    42541 agatagcgag tggaaacata aattcctaaa tagtttggat gatatcggta ttaccttgca
    42601 gtatgaagag ttgattgctg cttatgaaaa acaacgacca gcctactggc aggattagaa
    42661 aaaatagaaa aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttggagctta
    42721 acatccattt ccagcaattt tttagaaact acagtggact attctggatt caacacatta
    42781 taaaattatg acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga
    42841 tgtatcgttt gccctactaa agttggttac attatcatga ccagcaacaa ggcaggactt
    42901 gagcgtaagt tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt
    42961 agcatggatg aacttcgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa
    43021 aaacattgga tgaagatatt cttcttggtt gtatccttcc ttggaaacca gaagcctttg
    43081 aaaaactcaa agcatacggg gatggccgtg aagaacttat gactgatgta cgtggtacta
    43141 gctgttttgt tatcaagttt ggaaaagcag gtgaacaatt ggctgccaag ctttgggaag
    43201 aaggtaaaat ggtctacgcc tcatatgctt caatgacaaa acgattgaaa ctcgctatga
    43261 gagcaaggtg taatggtgtc tatggtcgat aaggacggca aactcatccc agaacaagga
    43321 ggagcacgtt caacttcacc agcaccagtt gtgatccgta aagggcttga cattgataaa
    43381 atcatgatgc acctgtcaga tacttttaac tcatgggact accgtcaggt tgagtattat
    43441 taagataaaa aaagaagtct agtgttatga gatattaaag ctcctaacac tggacttttt
    43501 gtttagaatt tcttttcttt ttctatagga tatggtattc tatgtagaaa atatatgtta
    43561 ataagtaatg ccaatattta aacatcatta gtaaaaggag ttagattgat gaataaaaga
    43621 aaagttagtt tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat
    43681 aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg
    43741 cctttggata ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa
    43801 aataagtctt tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt
    43861 tctggtggct cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa
    43921 gatcaagcta ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat
    43981 ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg aaaattctat ttttgatatg
    44041 aaaagatcaa caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc
    44101 tattctgagg gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac
    44161 cactttgttt ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa
    44221 ctggtgtcca aaacttatcc tgagttggag ccatcgaaat taggaactat gctttttgag
    44281 tattctaagc tttttatgga aaataaggaa gacaatagta caatggattc atcaaacaat
    44341 tttcgtcatc aattaactca atctctatta aagtctccaa acctcatcct tcgtggtgct
    44401 cctggcacag gaaagactta tcttgctaaa gaaattgcca aagaattaac ggatggcaac
    44461 gaagaccaaa tcggatttgt acaatttcac ccatcctatg attatacgga ttttgtagaa
    44521 ggtttaagac cagtatcaaa tggggatgga gctattgagt ttaggctaca ggacggtatt
    44581 tttaaagatt tttgtcagaa agcaaaagaa acccaattga ttggaggaca agataatttt
    44641 gatgaggctt gggattctta cttagaatat ataaatgttg ctgaagaaaa agaatatata
    44701 acaaaaacat cttacttatc tgttaatagt agacaaaatt tgtcagtaaa ttatgatagt
    44761 ggtgttccag gatggtcact acctagcaaa tatgtttacg agttgtataa agataaaaat
    44821 tataataagc aagaatacta caaaagtggt ggaaaaactg tcctagaaac attgagaaag
    44881 agatttggtt tgaaagacta tgtttcccca acagaaattg atactgataa gaaattcgtt
    44941 ttcatcatcg atgaaatcaa tcgtggggag atttctaaga tttttggcga actctttttc
    45001 tctatcgacc ctggctatcg tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta
    45061 cacgaaactg atgaaaagtt ctatatcccc gaaaatgttt acatcatcgg aactatgaat
    45121 gatattgatc gttcagtgga tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt
    45181 gaagttactg ccgagggtca agttggcatg ttggataaag agttgaatat ccatgcagaa
    45241 gaagcaaaaa ttcgtctaag aaacttgaac gctgctatcg aaaatgttca ggaattaaac
    45301 agtcattatc atattggacc aagttatttt cttaagttga aggatgtaga ttttgactat
    45361 gaattactct ggtctgatta tattaagcct ctcctagaag actacttgcg aggttcttat
    45421 gatgaggttg aaactttgga aactttgaaa aaagcatttg aactgacaaa taatgatcaa
    45481 actggtcaac aagatactgg tgataatgat gcggattact gataatcaat acaagattat
    45541 taaagaaaaa tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt
    45601 ggaaagtcta tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc
    45661 tgatttggat aaggaccaaa agatttttga aacagtcaat cagaaaatca agacagggaa
    45721 cgtgattggt tttcttggat atggtcagga aagattaacg atttcctcac gattttctga
    45781 tgagagtaat gaccattttt tgcattatct cttaaacaag attcttcata tcaatctcac
    45841 tagtttagat gttgctttgt ctcgtgaaga gaggctttat caacttttgg tgtatctctt
    45901 tcccaagtat ctacaagctg ctattcgaaa aggtctttat aaggaatatc atcgattttc
    45961 tcataacgac agtaatgtta agggagtgat tgatgtaaga agccatctca agaaaaatct
    46021 tcctttcacg ggaaatattg cctacgcaac gagagagttc acctatgata atcccctcat
    46081 gcagttggtc cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt
    46141 actagataat ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc
    46201 ttataaacta gctgatcgtg ctaagattat tcggggaaat caatctaaac ctatacgtca
    46261 tgcatacttt cacgagtaca gaaacttaca agaactttgt ctgatgatcc taaaccaaga
    46321 aaagcacggt ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg
    46381 gctttgggaa gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa
    46441 ggataagacg gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt
    46501 ttatgacaga gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga
    46561 aaaaggaatc aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc
    46621 tgagaaggct ggactgattt ttcctagtat ggagcagtca gtaaatagtg aaataggaaa
    46681 agtagctggc tatggagctc aattgaagaa gtggtctatt cgaatccctc agaatgcctc
    46741 attctatagt acattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat
    46801 tgatgaagaa gtggggagaa aataatttcc cctctttctt ttatttttaa cacaagtaaa
    46861 acccgaacga tatattttaa ttcataaaat aatttgacaa aaactgtact ttggtttata
    46921 ataaattaag gaaacgtcgg aaaaggcgta gtgatgcaag agcataggta ggtcattaca
    46981 aaagaaacga gacatcgata tgttaaatga atttccaatt tttgattacg aagatattca
    47041 attgattcca aataaatgtg tcattaaaag ccgtgcagaa gcggatacaa gtgtcacttt
    47101 aggaaatcac acctttaaac tacctgttgt gccagcgaat atgcagacga ttttggatga
    47161 aaatgtagca gagcaactgg ctaaaggtgg ttacttctac attatgcacc gttttgatga
    47221 ggcaggacgc attcctttta ttaaacgaat gcacgatcaa gggctcattg cttctatctc
    47281 tgtcggtgtt aaggattatg agtatgattt cgttagacag ctcaaggctg atgctcctga
    47341 gtatatcact attgatattg ctcatggtca tgcggatagc gtgatttcta tgattcaaca
    47401 catcaagaaa gaattgccag atacctttgt cattgctgga aatgtgggaa caccagaagc
    47461 tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag gtcggaatcg gtcctggtaa
    47521 ggtttgtatc accaaggtta agactggttt tggtacaggt ggttggcagt tggctgctct
    47581 acgctggtgt gccaaggctg cgcgtaaacc gattatcgct gatggaggaa ttcgtactca
    47641 cggtgatatt gctaagtcta tccgcttcgg tgctagcatg atcatgattg gttccctctt
    47701 tgcaggacac attgaaagtc cagggaaaac gattgaagtc gatggtgaac agttcaaaga
    47761 atattatggt tcagcctcac aatatcaaaa aggtgcttac aaaaatgtgg aaggcaaacg
    47821 tatcttgctt cctgctaaag gtcatctgca agacacttta actgagatgg aacaagacct
    47881 tcaaagtgct atttcttatg caggtggacg tcaggttgct gaccttaaac acgttgatta
    47941 tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc cactaagacg gggtctttga
    48001 ccaaaaaact tgttattaga gcaaatttct gttataataa aacaagtttc cacccttagt
    48061 gtaatggata tcacgtaaga ttccggttct tgagatgggg gttcgattcc ctcagggtgg
    48121 atgtaaacat cctaaaaagc ctttaatagg gcttttttct ttatcctgac tcaaatttgc
    48181 cgctaaaact gagaatctct gtctaaagaa ttcccaaatg ctttccagtc ccgttttaga
    48241 gtgactcagg gggctttttt tgatataata aaaaggacta ttatcagtta gaaagaggtt
    48301 ggtatgaaag aattacaaac tgtactaaag aatcattttg caatcgaatt tgcagacaaa
    48361 aagttactgg aaactgcctt tactcatacg agttatgcca atgagcaccg cctcttaaaa
    48421 atttcacaca atgaacgctt ggaattttta ggagacgctg ttctacagtt attgatttca
    48481 gaatatctat ataaaaaata tcctaaaaag cctgaaggtg acctatcaaa actccgtgct
    48541 atgattgtcc gtgaggagag tttagctggt tttgcgcgtg attgccagtt taaccagttt
    48601 atcaagttgg gtaaagggga agaaaaatca ggtggtcgca atcgtgacac cattcttggt
    48661 gatgcctttg aagcctttct tggtgccctt cttttggata aggatgtggc caaggtcaag
    48721 gaatttatct atcaagtcat cattcctaag gttgaagcag gcgagtttga gatgattaca
    48781 gactataaaa cccatctcca agagttgctt caggtcaatg gtgatgtggc tattcgttat
    48841 caggtgattt ctgaaacagg gcctgctcat gataaggtct ttgatgtaga agttcttgtt
    48901 gaaggtaaga gcatcggtca aggccaaggt cgttctaaga aattagcaga gcaggaagct
    48961 gccaaaaatg ccgttgagaa ggggctggat tcatgtattt aaaggaaatc gaaattcagg
    49021 ggttcaagtc ttttgctgat aagaccaagg tcgtttttga ccaaggtgtg acggcagttg
    49081 ttggacccaa tggatctgga aagtccaata ttacagaaag tctgcgttgg gctttggggg
    49141 agtctagtgt caagagtctc cgtgggggca agatgccgga tgtcatcttt gctggaaccg
    49201 aaagtcgcaa accgctcaat tatgcttctg tagttgtgac tctggataat catgacggat
    49261 ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca tatctatcgt agtggagata
    49321 gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga tattcatgac ctcttcttgg
    49381 atactggatt gggacgagat tccttctcta ttatttccca agggaaggtt gaggagattt
    49441 ttaattccaa gcctgaggaa cgacgagcta tttttgaaga agctgctgga gttttaaaat
    49501 acaagactcg cagaaaagaa accgagagta aactgcagca aactcaggat aatctggacc
    49561 gcttagagga cattatctac gagttggata atcaaatcaa gcctcttgaa aagcaagctg
    49621 agaatgcccg taagttttta gacttggaag gacaacgtaa ggctatttat ttagatgttc
    49681 tggttgctca aatcaaggaa aataaggctg aactagagtc gacagaagaa gagttggctc
    49741 aggttcaaga actcttgatg agttattacc aaaagcgtga aaaattagaa gaagaaaatc
    49801 aaactcttaa aaagcaacgc caagatttac aggctgaaat ggccaaagac caaggcagtt
    49861 tgatggattt gaccagtctg attagtgatt tagagagaaa attagcccta tcgaaattag
    49921 aatctgagca agtagccctg aatcaacagg aagcacaagc tcgtttggct gttttggagg
    49981 ataagagaaa ttcactcagc caagaaaaat ctgataaaga aagctcttta gtacttttag
    50041 aggaaaatct agtccaaaat aatcaaaaac tcaatcgttt agaagctgaa ttgctagctt
    50101 tttcagatga tcctgatcag atgattgagc ttttgcgtga acgctttgtg gcgcttttac
    50161 aagaagaagc ggatgtctca aaccaactga cccgcatcga gaatgagttg gaaaatagtc
    50221 gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct gaaagagcaa ttagctacag
    50281 ctaaagagaa ggctagtcag caaaaagacg agcttgaaac tgccaaggtg caggttcaga
    50341 aattattgac tgactatcaa gctattgcca aggagcaaga ggagcaaaaa acttcctatc
    50401 aagctcaaca aagtcaactc tttgaccgtc tggatagtct taaaaacaag caggctagag
    50461 ctcaaagttt ggaaaacatc cttagaaatc acagtaactt ttatgcaggt gtaaagagtg
    50521 ttctccaaga aaaagaccgc cttggtggga ttattggtgc tgttagtgag catttgacct
    50581 ttgatgtgca ttatcaaact gccttagaga ttgcacttgg agccagcagt cagcatatca
    50641 tcgtagaaga tgaagagtcg gcaaccaagg cgattgattt cctcaaacga aatagagctg
    50701 gtcgtgcaac cttccttccg ttgacgacta tcaaggcgcg tacgatttct agtcagaacc
    50761 aagatgttat cgctgcaagt gcgggatttc taggcatggc agatgagttg gtgacattcg
    50821 atacgagact ggaagctatt ttcaagaact tgctagctac gacagcgatt tttgataccg
    50881 ttgagcatgc gcgtgcagca gcgcgcaaag ttcgttatca ggttcgtatg gtgactttgg
    50941 acggtacaga gttgcgcaca ggtggttctt acgcaggtgg agccaatcgt cagaataaca
    51001 gtattttcat caagccagaa ctggagcaat tacaaaaaga aattgctgaa gaagaagcaa
    51061 gtttgcgttc agatgaagtg agtttgaaga acttgcaaga tgagctagct agattgacag
    51121 aaagattaga agccatcaaa tctcagggag agcaggctcg tattcaggag caaggcttgt
    51181 ccctcgccta tcagcagacc agtcagcaag ttgaagagct agaaactctt tggaaactcc
    51241 aagaagagga attaaatcgt ctttctgagg gagaatggca agcggataag gaaaaatgcc
    51301 aagagcgcct tactacaatc actagtgaaa agaataatct ggaagctgag attgaagaga
    51361 ttaagtctaa taaaaacgcc atccaagaac gttatcaaaa cttgcaggaa gagctagctc
    51421 aagctcgtct acttaagaca gaactgcaag ggcaaaaacg ttatgaagtg actgatattg
    51481 aacgcttagg taaggaacta gataatcttg atattgagca agaagaaatt cagcgccttc
    51541 ttcaagaaaa ggttgacaat cttgagaagg ttgatacaga attgctcagt caacaggcgg
    51601 aagaatccaa aactcagaaa acgaacctcc aacaaggttt gattcgcaaa cagtttgagt
    51661 tggatgatat agaaggtcag ctggatgata ttgctagtca tttggatcag gctcgccagc
    51721 agaatgagga gtggattcgc aagcaaacac gtgctgaagc caagaaagaa aaggtcagcg
    51781 agcgcttgcg ccatctacaa agtcaattaa cagaccagta ccagattagc tatactgaag
    51841 cactagaaaa agcgcatgag ttggacaatc tcaatctggc agagcaagag gtgcaggatt
    51901 tagagaaggc tattcgctca ctgggtcctg tcaacttgga tgctattgac cagtacgaag
    51961 aagttcacag ccgtctggat ttcctcaata gccagcgaga tgacattttg tcagcgaaaa
    52021 atctgcttct tgagactatt acagagatga atgatgaggt caaggaacgc tttaaatcaa
    52081 cctttgaagc tatccgtgag tcctttaaag tgaccttcaa gcagatgttt ggcggaggtc
    52141 aagcggacct gattttgact gagggagact tgctgacagc tggtgtggag atttctgttc
    52201 aacctccagg taagaaaatc cagtccctta atctcatgag tggtggtgaa aaagctctat
    52261 cggctcttgc cttgctcttc tccattattc gtgtcaagac tattccattt gttatcttgg
    52321 atgaggtgga agctgcgctg gatgaagcca atgttaaacg ttttggggat tacctcaacc
    52381 gctttgacaa ggacagccag tttatcgtcg taacccaccg taagggaacc atggcagcgg
    52441 ctgattccat ctatggagtg accatgcaag aatcgggtgt ttcaaagatt gtttcagtta
    52501 agttaaaaga tttagaaagt attgaaggat gacaattaaa ttagtagcaa cggatatgga
    52561 cggaaccttc ctagatggga atgggcgctt tgatatggag cgcctcaagt ctcttttgac
    52621 ttcctacaag gaaaaaggga tttactttgc ggtggcttcg gggcgcggat ttctgtctct
    52681 agaaaaatta tttgctgatg ttcgtaatga tattattttc attgcggaaa atggcagttt
    52741 ggtcgaatat caaggtcagg acttgtatga agcgaccatg tctcgtgact tttatctagc
    52801 aacttttgaa aagttacaaa cttcacctta tgtagatatc aataaactgc tcttgacggg
    52861 gaaaaaagga tcttatgtgc tagatacggt tgatgagacc tatttgaaag tgagtcagca
    52921 ctataatgaa aatatccaaa aagtagcgag tctggaagat attacagatg acattttcaa
    52981 atttacaacc aacttcacag aagaaacgct ggaagctggg gaagcttggg ttaatgaaca
    53041 tgtccctggt gttaaggcca tgacaactgg ctttgagtcc attgatattg ttctggacta
    53101 tgtcgataag ggagtggcca ttgttgaatt agctaaaaaa cttggtatca caatggatca
    53161 ggttatggct tttggagaca atctaaatga cttgcatatg atgcaggttg tggggcatcc
    53221 tgtggctcct gaaaatgcac gatctgaaat tttagaatta gcagagacag tgattggtca
    53281 ccataaggac cagtcggtta tagcttatat ggagggctta taatggcaga tataaaattg
    53341 attgcattgg acttggacgg gaccttgctg actactgata aaaggctgac ggatcgcacc
    53401 aaggcaacct tgaaagctgc gcgtgatcgt ggtatcaagg tcgtattgac aactggtcgt
    53461 cccctaaaag ccatggattt ctttctccat gagctaggga ctgacggcca cgaagatgag
    53521 tataccatta cttttaatgg tggtttggtt cagaaaaata caggtgaaat ccttgataag
    53581 acagtctttt catatgatga tgtagcacgc ttgtatgaag aaacagagaa attatcactg
    53641 cctcttgatg ccatctcaga aggaacagtt tatcaaatcc aatcggacca agaaagtctt
    53701 tatgccaaat ttaatccagc cttgaccttt gttccagtgg actttgaaga cttatctagt
    53761 caaatgacct acaacaaatg cgtgaccgcc tttgctcaag aacccttgga tgcagccatt
    53821 cagaagattt ctccagaatt gtttgaccaa tatgaaatct ttaaatcacg tgaaatgttg
    53881 ctagaatggt caccaaagaa tgttcataaa gcaacaggtt tggcaaaact aatcagccat
    53941 cttggaatcg accaaagcca agtgatggct tgtggtgacg aggccaatga cctctctatg
    54001 attgaatggg caggtcttgg tgttgctatg caaaacgctg ttcctgaagt aaaggcagcc
    54061 gcaaatgtag tgacgccgat gaccaacgat gaggaagctg tcgcctgggc tatcgaagaa
    54121 tatgtgctaa aggagaacta agatatggga ttgtttgacc gtctattcgg aaaaaaagaa
    54181 gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa atcttgattt gtctgaagat
    54241 gttgatccta ccttcacaga agttgaggaa gttcctcagg aagaagcaga ggttgaaatt
    54301 gttgaacaag ctgtgttcca agaggaggaa atccaagaca cagttgaaga aagtcaggat
    54361 tcagagccag ctgtaggggt ttctcaagaa gaaatagaag aattaccaaa ctcagaagaa
    54421 ttaccagagg aagagaagct tgagcacgaa ggaactatag aagaaaataa ttctgaagtt
    54481 cttgaaccag aaaggcctca aacagaagaa actgttcagg aaaaatatga ccgcagtctc
    54541 aagaagactc gtacgggctt cggtgctcgc ttgaacgcct tctttgctaa cttccgctct
    54601 gttgacgaag aatttttcga ggaactggaa gaactgctga ttatgagtga tgttggtgtc
    54661 caagtcgctt ctaacttaac ggaggaacta cgttacgaag ccaagcttga aaatgccaag
    54721 aaacctgatg cacttcgtcg tgtcatcatt gagaaattgg ttgagcttta tgaaaaggat
    54781 ggtagctacg atgaaagcat ccacttccaa gataacttga cagttatgct ctttgttggt
    54841 gtgaatggtg ttgggaaaac aacttctatt ggaaaactag cccaccgcta caaacgaact
    54901 ggtaagaagg tcatgctggt tgcagcagat accttccgtg cgggtgcagt agctcagcta
    54961 gctgaatggg gccgacgagt agatgttcca gtagtaactg gacctgaaaa agctgatcca
    55021 gccagcgtga tctttgatgg tatggaacgt gccgtggctg aaggtatcga tattctcatg
    55081 attgatactg ctggtcgtct gcaaaataag gataacctta tggctgagtt ggaaaagatt
    55141 ggtcgtatta tcaaacgtgt tgtgccagaa gcaccacatg aaaccttctt ggcacttgat
    55201 gcatcaacag gtcaaaatgc cctagtacag gccaaagaat tttcgaaaat cacaccttta
    55261 acgggaattg ttttgactaa gattgatgga actgctcgag gaggtgtggt tctagccatt
    55321 cgtgaagaac tcaatattcc tgtaaaattg attggttttg gtgaaaaaat cgatgatatt
    55381 ggagagttta actcagaaaa ctttatgaaa ggtctcttgg aaggtttaat ctaatcagaa
    55441 gcaaaaatcc tgcaaggcat aaacttgcag gaaatttttt tattctaagc gaccatcttg
    55501 acgataggcg atatctggtt gccaagtcca tttggcaccg aatttttcaa gtaggtcaaa
    55561 gctggcttga ggtcccatgc ttccagcttt atagtcatga agtggggcac cattttcagc
    55621 ccagagcttt tcaatacgat caatcaactt ccatgacgca ccaacttcat cccagtggct
    55681 aaagttggtt gagttgttat ttaggacatc ataaatcaat ttctcgtatg gttctggaga
    55741 agcaccagtt gcagtcgcgt ctgtacgata atcaagtgag ttaggagcca agttaaattc
    55801 ttctcctact tgcttcccat ttaggctaag agagaagcct tctgttggtt gaatatagat
    55861 ggtcaaaata tttggagcaa gtggttctcc aaagatagaa tccatttgtt taaagacgat
    55921 gttgacatga gttccttttt cagtcagtcg tttacctgta cggaaaaaga aaggaacacc
    55981 acggaatcga tcgctgtcta caaagaaggc accagatgta aaggtttcag ttgttgattc
    56041 tggattcaca tttggttcgc tacgataaga gatgtatttc atgccatcaa tcttaccaga
    56101 gcggtattgc ccacggataa agtgttcttt gagttcttca tcagttggat gatagaggtt
    56161 tttaaagacc ttaatctttt cagcacgaat ctcgtctttt gtgaagcttg ctggtttgtc
    56221 catggcgagg agcgaaagaa gttgtagagt gtggttttgg accatgtcac ggagggcacc
    56281 ggattggtca tagtagccac cacgttcttc tacacccaag cgctccgcaa aggtaatttg
    56341 aacattgtcg ataaaatcct tgttccaaac gttttcaaaa atcaagtttg caaagcgaac
    56401 tgcaaagatg ctttggatca tttccttacc aagataatgg tcgatacgga aaatttgttc
    56461 ttcgtcaaat gttgctagga gttcgtcatt caacttgctt gcagttgcgt aatctgtacc
    56521 aaatggtttt tcaacgatca agcgctcaaa acctttgcca tcgacaatgt tttcagattt
    56581 gaggtgtttg gcaatggttc caaagaactg aggtgccata gacaagaaga agagcttatt
    56641 gtgttcagct tggtattttt cattaagctc agcttgtaat tgacgcaaag caatataatg
    56701 ttccgaatca ttgacatcat ggctttgata gtagaagtgg ctagcaaatt cttgggcttg
    56761 ctcggtacta tctgccaaat caaggatgga ctcgacaact acagattcaa aatattcctt
    56821 actccaaggt ctacgggcag ttccaataac ggcaaagtgc ttggaaagat tgccggattt
    56881 atatagtcta aaaagggaag ggtagagctt gcgtttagcc aggtctccac tcgcaccgaa
    56941 aattgtaaca ataaccttag atgacatcta gctacctaat ttctattttt attcctagtc
    57001 ttgctaggta tgaggaaacc tcatttcata aacttaattc taacataatt ttccgaaaaa
    57061 tcaaaaattc caatacgagg tagaaaaact gcaaggaaat ccttacagtt tgagtttaga
    57121 cgtttaagac cttatctaag aactctttca gacgagggtg ttgtgggtta tcaaagattt
    57181 ggtcaggtgt tccgtcttca aggaactcgc catctgcagt aaagataacg cggttggcaa
    57241 cctgacgagc aaatcccatc tcatgggtta cgataatcat ggtcatgcct tgctcagcca
    57301 attccttcat aacgttaagt acgtctccaa ccatctcagg gtcaagggca gaagttggtt
    57361 catcgaagag catgatgtct ggattcattg ctaggccacg agcgatggcc acacgttgtt
    57421 tttgaccacc tgataggcta tctggattgg cattagcttt atctgctagt ccaacctttt
    57481 caagcaactc cattcccaat tcctcagctt cttccttagt catcaacttg tgctcaatag
    57541 gagcaaaggt gatgttgtcc aatacagaca tatgagggaa gaggttgaag tgttggaata
    57601 ccatgccgat attttcacgg acgtggtcaa cattggttgt tttttcagtt aaatcatagc
    57661 cgttcacagt gatgtgaccg ctagtgactt cttctaaaag attgaggcta cggaggaaag
    57721 ttgacttacc agaacctgaa ggaccgatga tacaaacaac atctccttca tagaacttag
    57781 tcgtaattcc ttttaggact tcattttttc catagtgctt gtgtaaatca tttacatcaa
    57841 tttttaattt tgccattaac gaatcctctt ttctaagcgt ttcgctagtc tagtcaaaag
    57901 tgtgataatt acaagataga agatagcaag gattgcatac atcttgaaac tttggtagtt
    57961 acgagcaatg ataatcttac cagtttggaa gagttcaacc aaaccgatag cagatacgat
    58021 agttgtatct ttaagagcga taacgaattg gttgacaaag tttggcaaca tcaatttagt
    58081 tgcttgtggc aagataatct tacgcatggt ttttccataa gagataccca agcttcggct
    58141 ggcttccatt tggccaactg gaacggcctg aataccacca cgaacgattt cagcgatata
    58201 agcagccgca ttgagtgaga gggcaattgt tccagctaca aagtcgttaa ttgggctttg
    58261 ttggcctgtg atagactcga tgaagtttgg aattccccag aagatgaagg ctgcaagaat
    58321 catcaatgga ataccacgaa taacgtcaac gaaaatctca gagatgacgc gaagagattt
    58381 gtatgggcta acgctaaaca taccgaagat aattccgatg acaatggcaa tagcaaatga
    58441 gataagagct agagcaagag tgataccaag accgctaagg agttgtttgt agttgttttg
    58501 aagcaagccc cagagcgttg tttcgtcaac agtacttgtt gaagcagttg aagattcgct
    58561 agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt gctttaaggt ttgcaagtcc
    58621 gttgttgaac atttcaatca gttctggatt tgctcctttt ttaacggcaa aggctgtttc
    58681 accgattgga gttccagaga ttggagtttt caatttttga ccttggctga tagaatattt
    58741 gagaacaggt tcatcatcca taacggcatc aatggcacca gtgtttaaac tgtcatacat
    58801 tgaagaacca tcagcaaagg ttttgatttt gtaaccgtat ttgctttgat tttctgttag
    58861 gaaggtttga gaagcagttc cgtttttaac accgactgtc tttcctttta gatcttcata
    58921 agaagcaata ttgcttgatt ctttgacacc aagaatggta ttagcagtgt agtatgattc
    58981 tgagaagtca aaagttgcct tacgagcatc tgtgacagac ataccagcaa tgataccatc
    59041 ggcttgacca gcttggacag cactgatagc agcatcaaaa ccagggttgg tgatttcaat
    59101 ttcaaaacct tggtctttag cgattgcctt aatcaattcc atatcaatac cagtgtattg
    59161 gttgcttgaa ttttggaaaa caaaaggtgc aaaagaagaa tcgctggcaa tgatatattt
    59221 agccttaaca ggaatagctt ttaatcctgc gagagtggtt gtagttggca ctgctgaaga
    59281 tgatgaagca gtccatttct tgataatttt atcaagacta ccatcttttt tcatttcagc
    59341 caaggcttgg ttaaattcag taaccaggtg ttcgtattta cttccttttt tcacaccgaa
    59401 agcaaaactt cctacagctt caccatccat ttcaatatgg aggtcttgac cttggttaat
    59461 ggcatattcg ataacaggtt tgtcatccat catggcatcg atggcaccag cactcaagct
    59521 gttgttcatt aaatccccag tgtcaaatgt tttaatagta aagccgtatt tatctttgat
    59581 tgtttcaagg aaacgttgag cggcagttcc gtttttaaca ccaacggttt tgccagttaa
    59641 ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca atgacaactt ttgtatcata
    59701 gtaagtatca gacatggtga agactttttc acgttcttta gtctttgtca tccctgccat
    59761 gatagcgtcg gcttgcccag cttgaaccgc attgactgct gcgtcaaatc caggatagga
    59821 catctgaatg ttccagcctt taatctcagc gactttgtta ataatgtcaa catcaattcc
    59881 tttataagtt tgatctgaat ctttaaactc aaaaggtgca taggcggtat cagaaacaat
    59941 cttaatcgtt tctgctttgg caatacctaa tgagaaaatt gggaataaaa ttagcaaaaa
    60001 tgctagaaat tttttcttca tttttagtct ccttttccga atattctctc attatatcag
    60061 aaaaagtaaa aaaaggcaaa tttttatatt ttcgtgtcag aaaatataac attgattttt
    60121 tcctttcctt gaattgctat taaaaagtgc tataataata gtatatatag aagaaaagag
    60181 gacggggata tgaagaacaa aagaatattt aaagacttcc aagcttcaaa aatgagttta
    60241 aacatttaca caagcccctt gttagtcttt gtttttgtct tcataggaga gtttgtggct
    60301 tttactttgt atggtattgg cttgttagct ctcatcggac ttgctagaaa ttttggagag
    60361 gctggtcaaa atcttgcaag ctacttgcag accttgcatc agagcttgac ggataaaaca
    60421 agtgactttc gtttaatttt aggattactg gcctttggtt ttattcttaa cactgtgttc
    60481 agatggacaa gaaaagttga gaaaagacct attcgaacct tgggatttta tagagagaat
    60541 ttcctcagca atcttctgaa aggatttagt ctaggtctgg cactttttct tctgaccttg
    60601 ttaggtttgg tggtcttagg tcaatatcgt ttggaatcca ttcacttgaa tccttattct
    60661 cttgcctttg tcgtctttac tatcccattt tggattttac aaggaacggc agaagaattg
    60721 gttactcgtg cttggctgat tccacaattg gctaagagaa ccaatcttaa agtcgctatt
    60781 atcatatcta gtagtctctt taccttactt catttaggaa atccaggcat aactttctta
    60841 tctgcaattg atctcttttt attcggagtt gccatgtccc tatatcttct taaaacagat
    60901 actatatggg gtataggtgg tattcatgga gcttggaatt tcgcacaggg aaacctcttt
    60961 ggagtattag ttagtggtca gtcttcagga acatcaatca tgagatttac tccacaaggc
    61021 aatcaagact ggctatcagg aggatctttt ggtattgagg gttccatcgt gtccagtatt
    61081 attttgtttc tgctgattct ttatctcgct catcaattaa agaaagaaaa tgaaaggatg
    61141 tgacttcggt ccgtcctttt cttcgtgaaa atgctacaag tatgctaaaa taggaatagc
    61201 acatggagag aggattctta tgatcaatcg cattacagat aatcaattta aactagtatc
    61261 aaaatatcaa ccttcaggag accaacctca agctattgag cagttggttg ataatatcga
    61321 ggggggagaa aaagctcaga ttctgatggg ggcgaccgga acagggaaga cctataccat
    61381 gagtcaggtc atttccaaag tcaataaacc aactctggtt attgcccaca ataaaactct
    61441 agcaggccag ctatatggag agtttaagga atttttccct gaaaatgcag ttgagtattt
    61501 cgtatcctac tatgattatt accagccaga ggcctatgta ccttctagtg atacctatat
    61561 tgagaaggat agttctgtca atgatgagat tgacaagctc cgccactcag cgacttcggc
    61621 tcttttggag cgtaatgatg ttattgtcgt ggcctcagtc tcttgtatct atggtttggg
    61681 ttcgcccaag gaatacgctg atagtgtcgt tagtctccgt ccaggtcttg aaatttctcg
    61741 tgataaactc ttgaatgact tggttgatat ccagtttgaa cgtaatgata ttgatttcca
    61801 acggggaaga tttcgtgttc gtggggatgt ggtggagatt ttcccagcat ctcgtgatga
    61861 acacgctttt cgagtagaat tttttggaga cgaaattgac cgtattcgtg aggttgaggc
    61921 cctgactggt caggtattgg gagaagtgga tcatttagcg attttcccag ctactcactt
    61981 tgtgaccaat gacgaccaca tggaagtggc cattgctaaa attcagactg agttggaaga
    62041 gcagttagct gtctttgaga atgagggcaa actgttagaa tcccagcgtt tgaaacagcg
    62101 gacagagtat gatatcgaaa tgttgcgtga gatgggctat accaacgggg ttgagaacta
    62161 ttcacgtcac atggatggac ggagcgaagg tgagcctcct tatacgctct tagatttctt
    62221 cccagatgat ttcttaatca tgattgacga gagtcacatg actatgggac aaataaaagg
    62281 catgtacaat ggagaccgtt cgcgtaaaga aatgctagta aattatggtt tccgtttgcc
    62341 gtctgctctg gacaatcgtc ctctccgtcg tgaagaattt gaaagccatg tgcatcagat
    62401 tgtttacgtt tcagcgacac caggtgatta tgaaggtgaa cagactgaga cagtgattga
    62461 gcaaatcatt cgtccaacag gactattgga tccagaggta gaagtccgtc cgacaatggg
    62521 acagattgat gacctcctag gtgaaatcaa tgcccgtgtt gaaaagaacg aacggacctt
    62581 tattacaacc ttgaccaaga aaatggcaga agatttgacc gactacttta aggaaatggg
    62641 catcaaggtc aagtacatgc actcggatat taagaccttg gaacggacgg agattatccg
    62701 tgacctgcgc ttgggtgtct ttgatgtctt ggtcggaatt aacctgctcc gtgaagggat
    62761 tgacgttcct gaagtgagct tggttgccat tctcgatgct gacaaggaag gtttcctacg
    62821 taacgaacgt ggactcatcc agaccattgg ccgcgctgcc cgtaatagcg aaggtcatgt
    62881 catcatgtat gcggacacgg ttacccagtc tatgcaacgt gccatcgatg aaactgcccg
    62941 tcgtcgcaaa atccagatgg cttataatga agagcatggt atcgtaccac aaaccattaa
    63001 gaaagaaatc cgtgacttga ttgccgtaac caagactgtt gccaaagaag aagacaagga
    63061 agttgatatc aatagtctta acaaacaaga gcgcaaagaa ctggtcaaga aactagagaa
    63121 acaaatgcaa gaagccgtcg aagtgcttga ctttgaacta gcagcacaga ttcgtgatat
    63181 gatgttggaa gtcaaggcct tggattaggg gaatagtatg atttatttaa gaaagttaaa
    63241 gaaagaagat ttgatgtctt tatgggaaat ggcttattca cagcttaatc cagtctggaa
    63301 acagtatgat gctccctatt atgatgatta tcagtatttt tcaaatttta aagaattcga
    63361 actacaaaaa tcagaatcca ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga
    63421 taaactagtt gggactgttt cgcgttattg ggtatgtaaa caaacaagat ggatggaatt
    63481 gggaattggt atttatgata aaaaattctg gaacactggt attgggaaaa ttgctatgtt
    63541 gcagtggata gataggacgt ttcaggatta cttggagttg gagcatctgg gtttgacaac
    63601 ttggtcagga aatattggta tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc
    63661 tcatattcca aaagttcgtt attatcaagg taaatatttt gatagtatta aatatggtat
    63721 tttgagagaa gactgggaga aaataaatga cgattattat caaattaatg aaaactcctg
    63781 aagagataga aggtaaatcc cttgttcact ggcaaacgtg gagagaagct tatgatgacc
    63841 ttttgcctgc ggaatttcag gagacaatga cattagaaag gtgtcgattc tttagtaaaa
    63901 agtatccaga aaatacatgg attgcgatgg atggtgtgaa ggtagttggt tttatcagtt
    63961 atggcaattt tcgtgatgag actattcaag ctggtgaaat tattgcttta tatgttttaa
    64021 aagactatta tggaaaagga atcgcacaaa agttagtgaa agtagctttg actgctcttg
    64081 atcatttttc tgaaattttc ttatgggtat tgaaagataa taagcgagcc attgctttct
    64141 atcaaaaaat gggttttact tttgatggac aagaaaaaat acttgaactt ggaaagccta
    64201 taaaggaaaa acggatggta ttctattcta aataatttta aaaagtagaa gctaatggca
    64261 ctggtacaag tctgaaaatt taataaatta gaaagtgagt aaatttatgt cacgttccca
    64321 attaacgatt ttaacaaaca tttgtcttat tgaagacctc gaaacgcagc gcgtggtgat
    64381 gcagtatcgc tctcctgaaa ccaatcgctg gtctggttat gcctttccag gaggacatgt
    64441 agaaaatggc gagtctttcg cagagtctgt cattcgtgaa atctatgaag agacaggatt
    64501 gactatccaa aatcctcaac ttgtcggtat taaaaattgg ccactagata caggtgggcg
    64561 ctatattgtc atttgttata aggcgactga gttctctggt acccttcgct cttcagatga
    64621 aggagaagtt tcttgggtgc aaaaagacca gattccaaac ttggatctgg cctatgatat
    64681 gttacccttg atggaaatga tggaagctcc ggacaaatct gaatttttct accctcgccg
    64741 tacagaagac gattgggaaa agaaaatttt ctaatccttt actaaataac ctagctgatc
    64801 caaggcctcc tcgatatagt ggaggtcttg ttgtgtttcg gcttcgacta ggtggtaatg
    64861 gacgccatct gtcaattcag atagaggtct aaagtcagaa tgctcgactt gttctagaaa
    64921 atgttgcaca tctctgcgac aagacagttt aagcaaggtt tcaatttctc cataaacggg
    64981 atggtcaatc aaggtattct ggacatgccc gccattatcg acaatagcaa ggagttcctg
    65041 accgatttct tcaacttcat gtttcacttt gaaaagtttg tgaacataag gattggtatc
    65101 aatttgctta tagatgtagc cacgattggt ggataggata ggagcgccat cggctctcaa
    65161 aattgcaatg tcctgcacaa tgacctgacg tgtgacatga aaatgttccg ccaaactttg
    65221 gccattaagg gctttaggag cttctttcaa gagttggagc agggcttgtt tgcgatcttt
    65281 tgtcatagct tttcctttta acggcgtttt cgaagcactt tatagacagc tagtgctaat
    65341 gtatagtcta ccatactatg gataattgtg ccaaatccaa ctagtacaaa tagaacatag
    65401 aacatgtttt ctacattggt acccgaagtt gcgtaaaaaa ggacacaggc taatacttca
    65461 gcaagggcat gaacaacagc caaaacaaag ttgaaaatcc aggaagattt tggtttatct
    65521 agggtatcgg ggaatttttg taggtaaaga gctcctaaag caccaaaaga tatatgggaa
    65581 aaagcccgaa aaacgataac catgggatag ccagccatca aaaatccaaa actagaggct
    65641 aggatgacaa aaactgccat caagggcgac aagaacatgg ctataaaaat agcgatgtgg
    65701 ctccccaaag tataggaagc aggtggaatg acaatcttga aaggcataac aattggaatc
    65761 aaaatcgcaa tagccgttaa aagggctgtc attgtcataa attgtgtctt tttccgtgta
    65821 ttcacaagaa tctccttttt aactgcatat acactagtat ggtacaataa accagacaat
    65881 aaagcaagaa tttacttggg tttatagatc attttttagt taaaagttat agtagattga
    65941 aactagaata gtccacctct acttctaaaa cattgttaga aatcgatttg gctgtcctga
    66001 tcgatttgtc ctgttcttat ttcgttttac tatagtaaag atttcattaa aaagaaactg
    66061 tatagagcaa aatctccacc ttcaggtttg aaagcggaga ttgtttttat tttttcaagg
    66121 tttgtagtcg tggaacaatg gctagggtta gaattgcaga aatgaccaat tcagcaattg
    66181 aatttgttga gataacggtt gccagaagaa gttggatatt tccattataa acatttccaa
    66241 ataggaagaa gattcctcca aggacaaaga tagtatttgt caaggaacca agggccccag
    66301 ctaaaatcag accagtcttg tttttcatca gtttatagac taagtaagga gttaaaccaa
    66361 tcaaaatacg tgggacgatg gcaatgatag ctgagtagat gtttccgttt ggtacgaagg
    66421 gagagaagag gtagcttgtc ggtagaatcg taatcgtgtt aaccgtcaag ctaagtaatc
    66481 ccatcaaaaa tccaagtgta accccaactc gtggaccata aataatgctg gcaataatga
    66541 caggaatatg aacaatggtc ggtttgattg gaaatggaaa aaggttaaag ataagtgagc
    66601 tcagaaagtg tatcacgagc atggtagcaa aaaagatagc aatgggtgca atattagagc
    66661 gttttttcat cgatagtttc ctttattctt tctaaaataa ttgtgaggtc agctaaagct
    66721 cctcgtccgt ggtctccaca agctagtagg gattccttag gagcaatcag ctgatagccg
    66781 taggtttcta atgttttcag attattctga gttactggat ggtcatacat ttttgtattc
    66841 atagcaggag ttattagttt gggaatatga cttggtaggg ctagagctgt actggttacc
    66901 atgttgtccg caaatccgtg agctagtttt gcaatagtgt tagcagttgc aggtaccacg
    66961 ataaataaat ctgctttttt tccaagttcg atatgattga cctgatcagg atagggttcc
    67021 ttcatgacat ccaagtggac aggattctgt gagagtacct gtagtgtcaa aggttggata
    67081 aactctgtag cagcctgagt cattaagaca gtgacttgat ggccttgttt ttttagagaa
    67141 ctgactaaat ctgccgactt ataagaggcg attgaacccg ttacagccaa gagaatgttt
    67201 gccatagttt tcctttctaa gaatgatagg cttgaatttt ttcaaggagg agttctgcaa
    67261 tttcttcttt agtctggact gtttgaagct gatttttctc aacaaatata gctcggtgct
    67321 gatctgttga aatttgagtc agatcattcg cgatgattaa atctgcttga ttcttgataa
    67381 gactttttcg tgcaatgtca accagatgat cttcggtaac atcaaccagc agtttgaaac
    67441 caatcagatg aatagtagga ttccattcct tgactaggga tatgattttg ggtgtctttt
    67501 taaggaacaa aacctgaacc tcatcagttg aagaaatctt ggcctgatga ttttgcttgc
    67561 ttaaaaattc ttttagattg gagctagcct gaacttcctc aagccctgtc atataaacag
    67621 gagtgtagtc agaaacagcc attgagtgga tcaagacctg ataatcctga acacgttctt
    67681 gcatttctat tagaaggtcc ttggtattgg taatttctcg aatacttagg ttaggatgag
    67741 gctctggctt cagagctcgt tttgtcgtaa ttaaacaaac ttcataccct gcagaaagca
    67801 aagtctctgt gataattttc cccaagtgac ctgtagaatg gttagtgata gagcggacgc
    67861 tatcgatagc ttcactggta ccgcccgatg taactaaaat tttcatagca ctattgtaca
    67921 caaaaataag cggtaagtaa aatgaaagtg ataaattttt ggtaaaaacg aagatttatt
    67981 atagtttcaa actataaagc catataaaat ttaagaaagg actctaaaag tcttaaaaac
    68041 agagatattt acgaacgttt agagagtttt aggatgttaa aaatcttgtt ttgtgatata
    68101 atgaattatc atataagagg ttagaggaat tttgaatgaa aacagatatt gaaatcgcac
    68161 agagtattga gttgaagcca attgttgatg ttgtagagaa acttggtatt tcttatgacg
    68221 atttggagtt gtacggaaag tacaaggcta aactcagctt tgataaaatt cgtgcagttg
    68281 agagcaatct agtcggtaaa ttgatcttgg ttactgccat caacccaaca cctgcaggtg
    68341 aaggaaagtc gacgcttacc attggtcttg cggatgcctt gaacaagatt ggcaagaaaa
    68401 ccatgattgc tatccgcgaa ccgtctcttg gtccagtcat ggggatcaag ggtggtgctg
    68461 ctggtggtgg gtatgcacaa gttctgccaa tggaagacat caacctccac tttactggag
    68521 atatgcatgc tattacaact gccaacaatg ccctttctgc cttgattgac aaccacttgc
    68581 accaagggaa tgagctggaa attgatcaac gtcgtatcct ctggaaacgc gttgtggact
    68641 tgaacgaccg tgcgctccgc catgtgactg ttggtcttgg tggtcctcta aacggtattc
    68701 cacgtgagga tggttttgat attacagttg cttcagaaat catggcaatt ctttgcttgg
    68761 caacggacat cgaggacttg aaacgtcgtt tggcgaatat cgttattggt tatcgctatg
    68821 accgtacgcc tgtttctgta ggtgatttgc aggttgaggg tgccttggct ttgattttga
    68881 aggatgctat taagccaaac ttggttcaga caatttacgg tacacctgcc tttgtacacg
    68941 gtggtccatt tgccaatatc gctcatggct gtaactctgt tttggcgacg acaacagccc
    69001 ttcacttggc tgattacact gttactgaag ctggttttgg tgcggacctt ggtgctgaga
    69061 aattccttga tatcaagaca ccaaacttgc caacatctcc agatgcagtt gtcattgtcg
    69121 caacccttcg tgcccttaag atgaatggtg gtgtggctaa agacgctctg actgaagaaa
    69181 atgtagaggc agttcgtgca ggttttgcta acttgaaacg tcacgttgaa aatatccgta
    69241 agttcggtat tccagcagtt gtagctatta acgaatttgt atctgataca gaagctgaaa
    69301 ttgcagcctt aaaagaactc tgtgcctcaa tcgatgtacc agttgaattg gctagtgtct
    69361 gggctgatgg agcagaaggt ggagtagcac ttgccgaaac agttgttaag acaattgctg
    69421 aaaatccagc taactataaa cgtttgtacg ataatgacct ttctgtccaa gaaaagattg
    69481 aaaaaattgt cactgaaatc tatcgtggta gcaaagtgaa ctttgagaag aaagctcaaa
    69541 cacaaattgc tcaaatcgtt caaaacggtt gggacaaatt gccaatttgt atggctaaaa
    69601 ctcaatacag tttctcagac aatccaaatg cgcttggagc accagaaaac tttgaaatta
    69661 ccattcgtga attggtacca aaattaggtg caggcttcat cgttgcctta actggtgatg
    69721 ttatgaccat gccaggtctt ccaaaacgtc cagcagctct caacatggat gttgaaagcg
    69781 atggaactgt actaggcttg ttctagtgga ttgaaattga ctttaagtga gtttggaaat
    69841 aatatccaag ctcatttttt ctcagactgc aagcagttca tcaataagat ttatactctt
    69901 cgaaaatctt ttcaaactac gtcagcttca ccttgccgta ggtatatgat actgactctg
    69961 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt
    70021 tgctctttga ttttcattga gtataagtag atagaaaagt tatatactat ctattgaaaa
    70081 tattataaat cagatacaaa gacaggtgaa accttctgtg ttatactaga gatatgttag
    70141 atttgaaaga atacggtatc gtcatgtggc cggaggagaa agtcatttct ttccgtgaga
    70201 aacttctcgc ttggtatgat gaaaacaaaa gagatttgcc ttggaggaga agtaaaaatc
    70261 cttatcacat ctgggtatct gaaatcatgc ttcagcagac cagggtggat acagttatcc
    70321 cttactacga aagatttttg gactggtttc caactgtcga aagtctggca actgcgcctg
    70381 aggagagttt actgaaagct tgggagggct tgggctatta ttctcgagtt cgcaatatgc
    70441 aggctgcagc ccagcagatt atgactgact ttggtggcca atttccaaat acctatgaag
    70501 gaatttccag cttgaaaggg attggacctt acacagcagg agccatttcc agtattgctt
    70561 ttaacttgcc tgagccagct gtagatggta atgtcatgcg ggtcttggcg cgtctgtttg
    70621 aagtcaacca cgatattggg attccaagta atcgaaaaat ttttcaggca atgatggaga
    70681 tcttgattaa tccagatcgt ccgggtgatt ttaatcaagc cttgatggac ttagggtctg
    70741 atattgagtc tcctgtaaat cccagacctg aagaaagccc agtcaaggac tttagtgcgg
    70801 catatcagaa tggaaccatg gaccgttatc caattaaatc tcctaagaaa aagccggttc
    70861 ctatttatct taaagcctta gttgtgaaaa attctcaagg acaattttta cttgaaaaaa
    70921 atgaaagcga aaagctcttg gcaggttttt ggcatttccc ctttatagaa gttgataact
    70981 tttcgcaaga agagcagttt gacctctttc atcaggttgc ggaagaaagt gtgaactctg
    71041 gccccagtcc agaagagagt ttccagcagg actatgacct agatgttgat tggcttgatg
    71101 tttgttttga tacagtccag catgttttta gtcatcgaaa atggcatgta cagattgtag
    71161 caggtcaggt gagtgacttc catgattttt cagataggga agttcgttgg ctttcaccag
    71221 aagaattcaa gaattaccca cttgccaaac cccaacaaaa aatctggcag gcttatgcac
    71281 aagccaactt agacagtagc caagactagc tattgtgtct tctgactatt ttttggtata
    71341 atagtagaga aaaaggtgaa catatgaaaa aaatactaat tgtagatgat gagaaaccaa
    71401 tctcggatat tatcaagttt aatatgacca aggaaggtta cgaagttgta actgctttta
    71461 atggtcgtga agcgctagag caatttgaag cagagcaacc agatattatt attctggatt
    71521 tgatgcttcc agaaattgat ggtttagaag ttgctaagac cattcgtaag acaagcagtg
    71581 tgcccattct tatgctttca gccaaagata gtgaatttga taaggttatc ggtttggaac
    71641 ttggggcaga tgactatgta acgaaaccct tctccaatcg tgagttgcag gcacgtgtta
    71701 aagctcttct gcgtcgttct caacctatgc cagtagatgg gcaggaagca gatagtaaac
    71761 ctcaacctat ccaaattggg gatttagaaa ttgttccaga cgcctacgtg gctaaaaaat
    71821 atggcgaaga actagactta acccatcgtg aatttgagct tttgtatcat ttagcatcgc
    71881 atacaggtca agtcatcacg cgcgaacact tgcttgagac tgtctggggt tatgactatt
    71941 ttggtgatgt ccgtacagtt gatgtgactg tacgacgtct gcgtgagaag attgaagata
    72001 cgcccagccg accagagtat atcttgacgc gccgtggtgt agggtattac atgagaaata
    72061 atgcttgatt tactgaaaca aaccattttt accagagatt ttatctttat cctgattttg
    72121 ttaggtttca tccttgttgt gaccctctta ttactggaaa atagacgtga taatattcag
    72181 ttgaagcaaa tcaatcaaaa ggttaaagat ttgattgcag gagattattc caaggttctt
    72241 gatatgcaag gtgggtctga aatcactaat attaccaata atttgaatga cttgtcggag
    72301 gttattcgtc tcactcagga aaatctagaa caagagagta agaggctaaa tagtattctg
    72361 ttttatatga cagatggggt tcttgcgacc aaccgtcggg gtcagattat catgattaac
    72421 gatacagcca agaagcaact ggggttggtt aaggaagatg ttctgaatag aagcattttg
    72481 gaattgctca agatagaaga aaactatgaa ttgcgtgatt tgattaccca aagtccagaa
    72541 ttgttgctag attcccaaga tatcaatggc gaatatttga accttcgagt tcgctttgcc
    72601 ttgatacgtc gagagtctgg ctttatttca ggtttggtgg ctgttttgca tgatacgacg
    72661 gagcaggaga aggaagaacg cgaacgaaga ctctttgttt ccaatgttag ccatgagtta
    72721 cggactcctc tgactagcgt aaaatcctat cttgaagcct tggatgaggg ggctttgtgt
    72781 gaaactgtag caccagactt tatcaaggtt tctcttgatg aaaccaaccg tatgatgcgc
    72841 atggtgacgg atctcctcca tctttcacgt attgataatg ctaccagtca tctagatgtg
    72901 gaactgatta acttcactgc ttttattacc tttatcctca atcgttttga caagatgaaa
    72961 ggacaggaaa aggagaaaaa atatgagttg gtgagagatt atcccatcaa ttctatctgg
    73021 atggaaattg atacagataa gatgacgcag gttgtcgaca atattttaaa taatgctatt
    73081 aagtattcgc cagatggggg taaaatcact gtcagaatga agacaactga agaccagatg
    73141 attttatcca tttctgacca cggtttgggg attcctaagc aggatttacc acgtatcttt
    73201 gaccgtttct atcgtgtgga tcgtgctaga agtcgtgcac aaggtggtac aggtctagga
    73261 ctgtctatcg ctaaagaaat tatcaaacaa cataagggct ttatttgggc caagagtgaa
    73321 tacggcaagg gttcaacctt taccattgtg ctcccttatg ataaggatgc agtgaaagaa
    73381 gaagtatggg aggatgaagt agaagactag aatgagtgaa ataggcttta aatacagtat
    73441 tttagcgtcg ggttccagtg gaaattcttt ttatctggaa acctcaaaaa agaagctttt
    73501 agtagatgca ggcttgtctg gcaagaaaat taccagtctg ctagctgaaa ttaaccgtaa
    73561 gccagaagac ctggatgcca tcttgattac ccatgagcat tcagatcata tccatggagt
    73621 aggcgttttg gctcgcaagt atggtatgga tctttatgcc aatgaaaaga cctggcaagc
    73681 tatggaaaat agtaaatatc ttggcaaggt ggattcttcg caaaagcata tttttgaaat
    73741 gggtaaaacc aaaacctttg gagatatcga catcgagagt tttggtgtaa gccatgatgc
    73801 agtcgcaccg cagttctatc gctttatgaa ggatgataag agttttgtcc ttttgacaga
    73861 tacaggttat gtcagtgacc gtatggcggg cattgtcgaa aatgcggatg gctatcttat
    73921 cgaggccaac catgatgtag agattttgcg atcaggttct tacgcttggc gactcaaaca
    73981 acgaatccta tctgaccttg gtcacctttc taacgaggac ggtgctgaag ctatgattcg
    74041 gacgctagga aatcgtacta agaagattta ccttgggcat ttatctaagg aaaataatat
    74101 caaggaactg gctcatatga ccatggtcaa tcagctggct caagctgatc tgggagtcgg
    74161 agtagacttt aaggtttatg atacctcacc agataccgca acaccattga cagagatata
    74221 aaaagaacgc tgagaaggtg ttctttttat attgactgaa cacctaaaaa gtaatacaat
    74281 ggtgttacca ttaaaaaagg gagcacaaaa gatgactact attacattaa aagtttctga
    74341 agctgataaa acatttatga aagcaatggc taagtttgaa ggagtttccc tttcggaact
    74401 tattcgcacc aaaactcttg aagccctaga agatgaatac gatgctcgtg tggcagattt
    74461 agcctatcaa gagtatttag aagacttgga aaaaggagtt gaacccatta cttgggaaga
    74521 aatgatgcat gatttaggct tgaaggatga ataatttgta taaattagtt ccaacaagac
    74581 gttttatcaa gcaattgaaa aaattggacc gttatacgca gaagctaatt acaaactatt
    74641 tacaaaccaa tgttttggaa ggcccaagac gacacggaaa ggctttggtt ggtaatcgcg
    74701 ttggtcaatg gcgctataga attggtaatt atcgagttat cgtacaaatt gtagatgatg
    74761 aattagtcgt tgctactcta gaagttggtc atcggagaga tatttattga attaaagctg
    74821 agtaataaca atatagaaag taaggagagt aaaaatttga agaaaaaatg cttttttgca
    74881 gattattatg atacaacaat tattttactt gctttaatct ctgttattct ggtattactt
    74941 ggatttgctg agatgattga tttggacaat ccgccttata gtattattga tttagtaatc
    75001 tggggtgttt ttgtaattga ttatagttgg cgctttttta ttactaaaag aaaatggcgc
    75061 tttattcttg aaaatatttt tgatttattg gctattctcc ctttaaatgc tatttttaca
    75121 gtgtttcgat tagggcgtat ctttcgttta gctaaactaa caaaattact gaaactgact
    75181 cgtttactta gaataattgg acttacaggt aaattagaaa gaaaaattag tagattctta
    75241 cggacaaatg gcttgattta tatcttgtat gttaatatct ttatcgtgct agtaggaagt
    75301 tcaattttat ctgtagttga agaaaaatcc ttctcagata gtctttggtg ggctcttgta
    75361 acggtaacga ctgttggata tggggatatt gttcctgctt ccatttttgg gaaatggcta
    75421 gcagttttac tgatgcttgt cggtattgga acaataggga tgttaacaag tgctttgacg
    75481 aacttttttg taaaggataa tccagatgaa cagataaaac ttgataaact ccaagatgaa
    75541 ttatctagtc agagaatatt actagagaaa caatctaaaa agatagaaga actacataaa
    75601 atgatacaag atttgattga aaaaacataa taaaaataaa gatgagaaaa agtttgaact
    75661 gaggagaaat caagtaagtt ttgacacaat agaacgcata ttatcaggta taaaaacttg
    75721 atactatgcg ttttattgtg ggaagatgta taatggattg aaataagata tgaacaaatc
    75781 gattaggaat ttaaagcatt ttataacaac gttttagagt aacggggtac tatttcatat
    75841 aatacaggaa aaaacaactc cctgatgatt caaggagttg tctatagtta aattagtttt
    75901 tagaagcttc ttggaattct ggatttttcc atgcttcgtc aataatagct tgcaattctt
    75961 tagcagatgc ttgcattttt tgagtttctg catcgttcaa tggaatgttt actggacgaa
    76021 cgataccatg tgcaccaaca acagctggtt gaccgataaa gacattctca actccgtatt
    76081 gaccttcttg gaatactgaa agtggaagta ctgcgttttc atcgtcaagg attgctttag
    76141 tgatacgagc aagggctact gcgataccgt agtatgttgc accttttttg ttgatgattg
    76201 tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa ttcagcttct tgaacatttt
    76261 gagtgtcttt aaggaattct tcaaggttta caccagcgat gttagcgtgt gaccaaacag
    76321 cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg cactgaacga gcatccacat
    76381 ccaatttttc agcaagtgct tgacggaaac gagctgagtc aagtgaagta cctgaaccga
    76441 taacgcgttc tttagggaaa ccagagaatt tccaagttga gtaagtcaaa acgtcaactg
    76501 ggttagcagc aacaaggaag atacctttga aaccagattc aacaacttga gttacgattg
    76561 atttgttgat agcaaggttt ttacctacaa ggtcaagacg agtttcacct ggtttttgag
    76621 gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca gtcagagtat tgagctgcat
    76681 agattttttt aggtgaagtg aaggcaaggg cgtgactaag gtcaagcgca tcaccaacag
    76741 ctttttcatg caattgtgga atttcgataa ttccaagctc ttgtgcaatt ccttggttaa
    76801 caagtgcaaa agcgtaagat gaacctacag caccatcacc gacaaggata acttttttgt
    76861 gttgtttagt tgaagtcatt gttttaaaca tctccttaat tttattaggg gattttccct
    76921 agacaacttc attctatcac ttttaaaaaa ctttgtcacg aatatgcctt atagttctcg
    76981 atgtaaacgt tttagtggtt tagaggctga aatagatggg aatttatggt ataatgttgt
    77041 tacttactaa ttgtgaaatg aggcatttat taatgcagga taaaaattta gtgaatgtca
    77101 atctgacaaa ggagatgaag gcaagtttta tcgactacgc catgagtgtt atcgtagcgc
    77161 gagctcttcc tgatgttcga gatggcttaa aacctgttca ccgtcgcatt ctctacggaa
    77221 tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa atctgctcgt attacagggg
    77281 atgtcatggg taaatatcac ccacacgggg attcctctat ttatgaagcc atggtccgta
    77341 tggctcaatg gtggagctac cgttacatgc ttgtagatgg tcacgggaat tttggttcca
    77401 tggatggaga tagtgctgcc gctcaacgtt ataccgaggc acgtatgagc aagattgctc
    77461 tggaaatgct tcgtgatatc aacaaaaata cagttgattt cgttgataac tatgatgcca
    77521 atgaacggga acccttggtc ttgccagcgc gttttccaaa ccttttggtt aatggagcaa
    77581 ctggtatcgc ggttgggatg gcaaccaata ttccacctca taatctgggt gaaaccattg
    77641 atgcagtgaa gttggtcatg gataatcctg aagtgactac caaggacttg atggaagtct
    77701 tgcctggacc agattttcca actggtgctc ttgtcatggg gaaatcaggt atccataagg
    77761 cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg tacagagatt gaaacgacta
    77821 agactggtcg tgagcgtatc gttgtaacag aatttcctta catggtcaat aaaaccaagg
    77881 tgcatgagca tattgttcgc ttggttcagg aaaaacgcat tgagggtatc acagcagtac
    77941 gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga agtcaagcgc gacgcctcag
    78001 ccaatgttat tctcaataac ctcttcaaaa tgacccaaat gcaaaccaat tttggtttca
    78061 atatgctcgc tatccaaaat ggtataccga aaattttgtc tcttcgtcag attttggatg
    78121 cttatatcga gcaccaaaaa gaagtggttg ttcgtcgtac acgttttgat aaggaaaaag
    78181 cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc gctagaccat atcgacgaag
    78241 tgattcgtat catccgtgct agtgaaacgg atgcggaagc tcaagctgag ttgatgagca
    78301 agtttaagct ttctgaacgt caaagtcaag ctatccttga tatgcgtctt cgtcgtttga
    78361 caggtttgga acgcgataag attcaatctg agtatgatga cctcttggct ctgattgcgg
    78421 atttagcaga tattcttgct aagcctgaac gtgtttctca aattatcaaa gacgaattgg
    78481 atgaagttaa acgtaaattt tctgataagc gccgtacaga gttgatgatt ggacaggtct
    78541 tgagtctcga ggatgaggac ttgattgaag aatcggatgt cttgattacc ctttctaaca
    78601 gaggctacat taagcgtttg gatcaggacg agttcactgc tcaaaaacgt gggggtcgtg
    78661 gtgtccaagg aacgggagtg aaagatgatg actttgttcg tgagttagtg tcaactagca
    78721 cacatgatca tctgctcttc ttcacaaaca agggacgtgt ctatcgtctt aaaggttatg
    78781 aaattcctga gtatggtcgg actgccaaag ggctaccagt agtcaatctc ttgaaattgg
    78841 atgaagacga aagtattcag acggttatca atgttgagtc tgatcgcagt gatgatgctt
    78901 atctcttctt tacaacccgt cacggtattg tgaagagaac tagtgttaag gagtttgcca
    78961 atattcgtca aaatggtctc aaagcgctga atttaaagga tgaagatgag ttaatcaatg
    79021 tcttgttggc agaaggagat atggatatta tcattggtac caagtttggt tatgcagttc
    79081 gctttaatca atcagccgtt cgtggtatga gccgtatcgc cactggtgtg aaaggtgtta
    79141 accttcgtga aggagacaca gttgttggtg ccagcttgat tactgatcaa gatgaggttc
    79201 ttattatcac agaaaaagga tatggtaagc gtacagtcgc tactgaatac ccaacaaaag
    79261 gtcgtggtgg taagggaatg cagacagcta aaattaccga aaaaaatggc ttgctggccg
    79321 gtcttatgac tgttcaaggg gatgaggatt tgatgattat cactgataca ggtgtcatga
    79381 ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc aactatggga gttaaagtaa
    79441 tgcgcctgga tcaagatgct cagatagtga ctttcacaac ggttgcggtg gcagaaaaag
    79501 aagaagttgg gacagaaaac gaaacagaag gtgaagcata atgtctcaaa aaaataataa
    79561 aaagaaaaac aagcgaaaaa atctgctgac aaatatccta gcaggatttc tgatattact
    79621 gtcactggct ttgattttta atactcaaat tcgaaatatt ttcatagtct ggaataccaa
    79681 taagtatcaa gttagccagg tatcaaaaga aaaattagaa gaaaatcagg atacagaagg
    79741 caattttgac tttgattctg tcaaagctat ctcttcggaa gctgttctaa cttctcaatg
    79801 ggatgctcaa aaattaccag ttattggggg aattgcaatt cctgaattgg aaatgaattt
    79861 gccgattttt aaaggacttg ataatgttaa tctcttctac ggagctggta caatgaaacg
    79921 cgagcaagta atgggagaag gaaattatag tctagctagt caccatatct ttggtgttga
    79981 taatgctaat aaaatgttat tttctccttt agataatgct aaaaatggca tgaagattta
    80041 tctaaccgat aaaaataaag tttatactta tgaaatacgt gaagtcaaac gtgtgacacc
    80101 ggatcgtgtt gatgaagttg atgatagaga tggggtcaat gaaatcacat tagtaacctg
    80161 tgaagacctt gctgctacag aacgtattat tgtcaaaggt gatttgaaag aaacaaaaga
    80221 ttattcacaa acatctgatg aaatcctaac agctttcaat caaccatata aacaatttta
    80281 ttaatacaaa tcagtgaaat catggatttc actgattttt taagattttc ataaaaatat
    80341 agtaaaatga aataagaata ggacgaatcg
//
LOCUS       DBEJJE010000003        73527 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEJJE010000003 DBEJJE010000000
VERSION     DBEJJE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.03"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            243..899
                     /locus_tag="ACL3F5_000158"
     CDS             243..899
                     /locus_tag="ACL3F5_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0514031.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            889..1212
                     /locus_tag="ACL3F5_000159"
     CDS             889..1212
                     /locus_tag="ACL3F5_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGR0514032.1"
                     /translation="MVSKYLLLAVIFSVLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1316..2146
                     /locus_tag="ACL3F5_000160"
     CDS             1316..2146
                     /locus_tag="ACL3F5_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0514033.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2300..3154
                     /locus_tag="ACL3F5_000161"
     CDS             2300..3154
                     /locus_tag="ACL3F5_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0514034.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3254..4627
                     /locus_tag="ACL3F5_000162"
     CDS             3254..4627
                     /locus_tag="ACL3F5_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0514035.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVHEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4620..5681
                     /locus_tag="ACL3F5_000163"
     CDS             4620..5681
                     /locus_tag="ACL3F5_000163"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0514036.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILTLLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMAKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5683..6375
                     /locus_tag="ACL3F5_000164"
     CDS             5683..6375
                     /locus_tag="ACL3F5_000164"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0514037.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6405..6974)
                     /locus_tag="ACL3F5_000165"
     CDS             complement(6405..6974)
                     /locus_tag="ACL3F5_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0514038.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7109..7723
                     /locus_tag="ACL3F5_000166"
     CDS             7109..7723
                     /locus_tag="ACL3F5_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0514039.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7701..9371
                     /locus_tag="ACL3F5_000167"
     CDS             7701..9371
                     /locus_tag="ACL3F5_000167"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0514040.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDRESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRKSIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9383..10669
                     /locus_tag="ACL3F5_000168"
     CDS             9383..10669
                     /locus_tag="ACL3F5_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0514041.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10721..11254
                     /locus_tag="ACL3F5_000169"
     CDS             10721..11254
                     /locus_tag="ACL3F5_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514042.1"
                     /translation="MKKKPIYLWILLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11332..11802
                     /gene="nrdI"
                     /locus_tag="ACL3F5_000170"
     CDS             11332..11802
                     /gene="nrdI"
                     /locus_tag="ACL3F5_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0514043.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12095..13357)
                     /locus_tag="ACL3F5_000171"
     CDS             complement(12095..13357)
                     /locus_tag="ACL3F5_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0514044.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13667..14125)
                     /locus_tag="ACL3F5_000172"
     CDS             complement(13667..14125)
                     /locus_tag="ACL3F5_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0514045.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14122..14562)
                     /locus_tag="ACL3F5_000173"
     CDS             complement(14122..14562)
                     /locus_tag="ACL3F5_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0514046.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14918..16867
                     /gene="mutL"
                     /locus_tag="ACL3F5_000174"
     CDS             14918..16867
                     /gene="mutL"
                     /locus_tag="ACL3F5_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0514047.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17192..17659)
                     /gene="ribE"
                     /locus_tag="ACL3F5_000175"
     CDS             complement(17192..17659)
                     /gene="ribE"
                     /locus_tag="ACL3F5_000175"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0514048.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17660..18865)
                     /locus_tag="ACL3F5_000176"
     CDS             complement(17660..18865)
                     /locus_tag="ACL3F5_000176"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0514049.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLIFSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18885..19520)
                     /gene="ribE"
                     /locus_tag="ACL3F5_000177"
     CDS             complement(18885..19520)
                     /gene="ribE"
                     /locus_tag="ACL3F5_000177"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0514050.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19505..20605)
                     /gene="ribD"
                     /locus_tag="ACL3F5_000178"
     CDS             complement(19505..20605)
                     /gene="ribD"
                     /locus_tag="ACL3F5_000178"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0514051.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20739..20853)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21010..21603
                     /gene="ruvA"
                     /locus_tag="ACL3F5_000179"
     CDS             21010..21603
                     /gene="ruvA"
                     /locus_tag="ACL3F5_000179"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0514052.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21613..22176
                     /locus_tag="ACL3F5_000180"
     CDS             21613..22176
                     /locus_tag="ACL3F5_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0514053.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFIG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22173..22850
                     /locus_tag="ACL3F5_000181"
     CDS             22173..22850
                     /locus_tag="ACL3F5_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0514054.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23005..24036)
                     /locus_tag="ACL3F5_000182"
     CDS             complement(23005..24036)
                     /locus_tag="ACL3F5_000182"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0514055.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24291..24974)
                     /locus_tag="ACL3F5_000183"
     CDS             complement(24291..24974)
                     /locus_tag="ACL3F5_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0514056.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24986..25930)
                     /locus_tag="ACL3F5_000184"
     CDS             complement(24986..25930)
                     /locus_tag="ACL3F5_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0514057.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26062..28893
                     /gene="uvrA"
                     /locus_tag="ACL3F5_000185"
     CDS             26062..28893
                     /gene="uvrA"
                     /locus_tag="ACL3F5_000185"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0514058.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28886..29947
                     /locus_tag="ACL3F5_000186"
     CDS             28886..29947
                     /locus_tag="ACL3F5_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0514059.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30079..30477
                     /gene="spx"
                     /locus_tag="ACL3F5_000187"
     CDS             30079..30477
                     /gene="spx"
                     /locus_tag="ACL3F5_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0514060.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30543..31112
                     /locus_tag="ACL3F5_000188"
     CDS             30543..31112
                     /locus_tag="ACL3F5_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0514061.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            31199..31465
                     /locus_tag="ACL3F5_000189"
     CDS             31199..31465
                     /locus_tag="ACL3F5_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0514062.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31469..31888
                     /gene="ruvX"
                     /locus_tag="ACL3F5_000190"
     CDS             31469..31888
                     /gene="ruvX"
                     /locus_tag="ACL3F5_000190"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0514063.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31904..32209
                     /locus_tag="ACL3F5_000191"
     CDS             31904..32209
                     /locus_tag="ACL3F5_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0514064.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32468..33718
                     /locus_tag="ACL3F5_000192"
     CDS             32468..33718
                     /locus_tag="ACL3F5_000192"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0514065.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33802..34254
                     /locus_tag="ACL3F5_000193"
     CDS             33802..34254
                     /locus_tag="ACL3F5_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0514066.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPAQQVQQPAQQNT
                     NTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGD
                     QKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34400..35932
                     /gene="cls"
                     /locus_tag="ACL3F5_000194"
     CDS             34400..35932
                     /gene="cls"
                     /locus_tag="ACL3F5_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0514067.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36010..36153
                     /locus_tag="ACL3F5_000195"
     CDS             36010..36153
                     /locus_tag="ACL3F5_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514068.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36190..37728
                     /locus_tag="ACL3F5_000196"
     CDS             36190..37728
                     /locus_tag="ACL3F5_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0514069.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37848..40055
                     /gene="nrdD"
                     /locus_tag="ACL3F5_000197"
     CDS             37848..40055
                     /gene="nrdD"
                     /locus_tag="ACL3F5_000197"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0514070.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40067..40207
                     /locus_tag="ACL3F5_000198"
     CDS             40067..40207
                     /locus_tag="ACL3F5_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514071.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40251..40757
                     /locus_tag="ACL3F5_000199"
     CDS             40251..40757
                     /locus_tag="ACL3F5_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514072.1"
                     /translation="MELRRPRLADKETVLEMMTEFEKFQSPHDGGFWNTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVVFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANDGIFEDARNGVER
                     YWIEVANE"
     gene            40750..41340
                     /gene="nrdG"
                     /locus_tag="ACL3F5_000200"
     CDS             40750..41340
                     /gene="nrdG"
                     /locus_tag="ACL3F5_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0514073.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41337..41954
                     /locus_tag="ACL3F5_000201"
     CDS             41337..41954
                     /locus_tag="ACL3F5_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0514074.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42220..42528
                     /gene="rpsJ"
                     /locus_tag="ACL3F5_000202"
     CDS             42220..42528
                     /gene="rpsJ"
                     /locus_tag="ACL3F5_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0514075.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42744..43370
                     /gene="rplC"
                     /locus_tag="ACL3F5_000203"
     CDS             42744..43370
                     /gene="rplC"
                     /locus_tag="ACL3F5_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0514076.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43395..44018
                     /gene="rplD"
                     /locus_tag="ACL3F5_000204"
     CDS             43395..44018
                     /gene="rplD"
                     /locus_tag="ACL3F5_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0514077.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44018..44314
                     /locus_tag="ACL3F5_000205"
     CDS             44018..44314
                     /locus_tag="ACL3F5_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0514078.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44332..45165
                     /gene="rplB"
                     /locus_tag="ACL3F5_000206"
     CDS             44332..45165
                     /gene="rplB"
                     /locus_tag="ACL3F5_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0514079.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL3F5_000207"
     CDS             45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL3F5_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0514080.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45562..45906
                     /gene="rplV"
                     /locus_tag="ACL3F5_000208"
     CDS             45562..45906
                     /gene="rplV"
                     /locus_tag="ACL3F5_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0514081.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL3F5_000209"
     CDS             45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL3F5_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0514082.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46576..46989
                     /gene="rplP"
                     /locus_tag="ACL3F5_000210"
     CDS             46576..46989
                     /gene="rplP"
                     /locus_tag="ACL3F5_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0514083.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL3F5_000211"
     CDS             46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL3F5_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0514084.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL3F5_000212"
     CDS             47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL3F5_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0514085.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47516..47884
                     /gene="rplN"
                     /locus_tag="ACL3F5_000213"
     CDS             47516..47884
                     /gene="rplN"
                     /locus_tag="ACL3F5_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0514086.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47962..48267
                     /gene="rplX"
                     /locus_tag="ACL3F5_000214"
     CDS             47962..48267
                     /gene="rplX"
                     /locus_tag="ACL3F5_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0514087.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48291..48833
                     /gene="rplE"
                     /locus_tag="ACL3F5_000215"
     CDS             48291..48833
                     /gene="rplE"
                     /locus_tag="ACL3F5_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0514088.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL3F5_000216"
     CDS             48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL3F5_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0514089.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL3F5_000217"
     CDS             49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL3F5_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0514090.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49995..50531
                     /gene="rplF"
                     /locus_tag="ACL3F5_000218"
     CDS             49995..50531
                     /gene="rplF"
                     /locus_tag="ACL3F5_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0514091.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50615..50971
                     /gene="rplR"
                     /locus_tag="ACL3F5_000219"
     CDS             50615..50971
                     /gene="rplR"
                     /locus_tag="ACL3F5_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0514092.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL3F5_000220"
     CDS             50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL3F5_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0514093.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL3F5_000221"
     CDS             51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL3F5_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0514094.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51824..52264
                     /gene="rplO"
                     /locus_tag="ACL3F5_000222"
     CDS             51824..52264
                     /gene="rplO"
                     /locus_tag="ACL3F5_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0514095.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52277..53587
                     /gene="secY"
                     /locus_tag="ACL3F5_000223"
     CDS             52277..53587
                     /gene="secY"
                     /locus_tag="ACL3F5_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0514096.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53738..54376
                     /locus_tag="ACL3F5_000224"
     CDS             53738..54376
                     /locus_tag="ACL3F5_000224"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0514097.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54493..54711
                     /gene="infA"
                     /locus_tag="ACL3F5_000225"
     CDS             54493..54711
                     /gene="infA"
                     /locus_tag="ACL3F5_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0514098.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL3F5_000226"
     CDS             54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL3F5_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0514099.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL3F5_000227"
     CDS             54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL3F5_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0514100.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL3F5_000228"
     CDS             55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL3F5_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0514101.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55679..56614
                     /locus_tag="ACL3F5_000229"
     CDS             55679..56614
                     /locus_tag="ACL3F5_000229"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0514102.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL3F5_000230"
     CDS             56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL3F5_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0514103.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57277..57543
                     /locus_tag="ACL3F5_000231"
     CDS             57277..57543
                     /locus_tag="ACL3F5_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0514104.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57553..58890
                     /locus_tag="ACL3F5_000232"
     CDS             57553..58890
                     /locus_tag="ACL3F5_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0514105.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59134..59826
                     /locus_tag="ACL3F5_000233"
     CDS             59134..59826
                     /locus_tag="ACL3F5_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0514106.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59929..61564)
                     /locus_tag="ACL3F5_000234"
                     /pseudo
     CDS             complement(59929..61564)
                     /locus_tag="ACL3F5_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61554..62645)
                     /locus_tag="ACL3F5_000235"
                     /pseudo
     CDS             complement(61554..62645)
                     /locus_tag="ACL3F5_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62658..63779)
                     /locus_tag="ACL3F5_000236"
                     /pseudo
     CDS             complement(62658..63779)
                     /locus_tag="ACL3F5_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(63996..64220)
                     /locus_tag="ACL3F5_000237"
                     /pseudo
     CDS             complement(63996..64220)
                     /locus_tag="ACL3F5_000237"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64268..65044)
                     /locus_tag="ACL3F5_000238"
     CDS             complement(64268..65044)
                     /locus_tag="ACL3F5_000238"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0514107.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65166..65912
                     /locus_tag="ACL3F5_000239"
     CDS             65166..65912
                     /locus_tag="ACL3F5_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0514108.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65925..66905
                     /locus_tag="ACL3F5_000240"
     CDS             65925..66905
                     /locus_tag="ACL3F5_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0514109.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67100..67420
                     /locus_tag="ACL3F5_000241"
     CDS             67100..67420
                     /locus_tag="ACL3F5_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0514110.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67466..67774
                     /locus_tag="ACL3F5_000242"
     CDS             67466..67774
                     /locus_tag="ACL3F5_000242"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0514111.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67791..69089
                     /locus_tag="ACL3F5_000243"
     CDS             67791..69089
                     /locus_tag="ACL3F5_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0514112.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69240..71678
                     /locus_tag="ACL3F5_000244"
     CDS             69240..71678
                     /locus_tag="ACL3F5_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0514113.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71697..72365
                     /locus_tag="ACL3F5_000245"
     CDS             71697..72365
                     /locus_tag="ACL3F5_000245"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0514114.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72383..73471
                     /locus_tag="ACL3F5_000246"
     CDS             72383..73471
                     /locus_tag="ACL3F5_000246"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0514115.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKSVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        22286 a        13373 c        16074 g        21794 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cagtgttttg agctgactac gtcagttcta tctgcttttc attgagtact
      181 attaagacaa tatgaggaga aagatgaaag aaaaaggatt ttaggagggg gcgcaggcag
      241 ccatgccaac ggctcttggc tatgtcagta tcggcctggc ctgtgggact atcggtgcgc
      301 cctatgtgac acctgttgag atgggcttga tgagtctctt tgtttatgct gggagtgccc
      361 agtttgccat gttggcactg attgtggttc aagctcctgt ggcagctatt gctatgacgg
      421 tttttctaat caacttgcgt ctctttttgt tgagtttaca cgcatcgact tatttccgtc
      481 ataccagtct ttggtacaat atcggtatgt ctagtatctt gacagatgag acctatggcg
      541 ttttgatggg tgaattggcc catacagaca aggtaaatcc tatgtggatg cacggaaaca
      601 atcttaacag ctatgtggct tggtttgtgg ggacagtagt cggaacggct ctgggtggcc
      661 tgctaccaaa tccagaaatc tttggcttgg attttgccct ggttgggatg tttattggta
      721 tttttgcttc gcaatttcag attatgcaaa gacggattcc tgtccgcaat ctgctcatta
      781 tcctagcagt tgttgcggtg tccttctttt tgctcttgac agtggtgtct cagtcactag
      841 ctgttctgtt tgcgacgcta cttggttgta gcatgggggt ggttttagat ggtcagtaag
      901 tatcttttat tagcagttat tttctctgtc ttggtgactt ggattctccg tatgattccc
      961 ttcatcttag tcaagtataa gggcttgcct gcaatcgttg agcgtttttt gaagttcttg
     1021 cccgtttcca ttatctttgc cttgattctt tcaagcgtag tgacaggtaa ggttgggagc
     1081 cttcctcaaa ttaaatggct agacttctta gccgtctttc caacagcttg ggtagccttt
     1141 cgctaccgca atctagtcgg aacagttctc tttggagtgg tcttgattgc catcttgcgt
     1201 ttggtctttt aaattaccca taaaaaaaac ttatcacaga gatagatatc atataatggc
     1261 gtaaatgctc tttttctgtt aagattataa ggtattctat tttggaggaa atgacatgaa
     1321 aaaaatcgtt aaatactcat ctcttgctgc cctaggactt gttgctgcag gtgtgcttgc
     1381 ggcttgctca gggggtgcta agaaagaagg agaagcagct agcaagaaag aaatcatcgt
     1441 tgcaaccaat ggatcaccaa ggccatttat ctatgaagaa aatggcgaat tgactggtta
     1501 cgagattgaa gtcgttcgcg ctatctttaa agattctgac aaatatgatg tcaagtttga
     1561 aaagacagaa tggtcaggtg tctttgctgg tcttgacgct gaccgttaca atatggctgt
     1621 caacaatctt agctacacta aagaacgtgc ggagaaatac ctctatgccg caccaattgc
     1681 ccaaaatcct aatgtccttg tcgtgaagaa agatgactct agtatcaagt ctctcgatga
     1741 tatcggtgga aaatcgacgg aagtcgttca agccactaca tcagctaagc agttagaagc
     1801 atacaatgct gaacacacgg acaacccaac tatccttaac tatactaagg cagacttcca
     1861 acaaatcatg gtacgtttga gcgatggaca atttgactac aagatttttg ataaaatcgg
     1921 tgttgaaaca gtgatcaaga accaaggttt ggacaacttg aaagttatcg aacttccaag
     1981 cgaccaacaa ccgtacgttt acccacttct tgctcaaggt caagatgagt tgaaatcgtt
     2041 tgtagacaaa cgcatcaaag aactttataa agatggaact cttgaaaaat tgtctaaaca
     2101 attcttcgga gacacttatc taccggcaga agctgatatt aaataatttc ttgaaatcat
     2161 ccattctgag taaggtgggt ggtttctcag tttttaggga tatagtttta aactatatat
     2221 ctgactatct aataacaatt tgtgaaatca aacaaattgt gagatactag tacggtatta
     2281 tttttaagga gaaagaatca tgaaaatcaa aaaatggctt ggtctagcag cccttgctac
     2341 agtcgcaggt ttggctcttg cagcttgcgg aaactcagaa aagaaagcag acaatgcaac
     2401 aactatcaaa atcgcaactg ttaaccgtag cggttctgaa gaaaaacgtt gggacaaaat
     2461 ccaagaattg gttaaaaaag acggaattac cttggaattt acagagttca cagactactc
     2521 acaaccaaac aaagcaactg ctgatggcga agtagatttg aacgctttcc aacactataa
     2581 cttcttgaac aactggaaca aagaaaacgg aaaagacctt gtagcgattg cagatactta
     2641 catctctcca atccgccttt actcaggttt gaatggaagt gccaacaagt acactaaagt
     2701 agaagacatc ccagcaaacg gagaaatcgc tgtaccgaat gacgctacaa acgaaagccg
     2761 tgcgctttat ttgcttcaat cagctggctt gattaaattg gatgtttctg gaactgctct
     2821 tgcaacagtt gccaacatca aagaaaatcc aaagaacttg aaaatcactg aattggacgc
     2881 tagccaaaca gctcgttcat tgtcatcagt tgacgctgcc gttgtaaaca ataccttcgt
     2941 tacagaagca aaattggact acaagaaagc acttttcaaa gaacaagctg atgaaaactc
     3001 aaaacaatgg tacaacatca ttgttgcgaa aaaagattgg gaaacatcac ctaaggctga
     3061 tgctatcaag aaagtaatcg cagcttacca cacagatgac gtgaaaaaag ttatcgaaga
     3121 aacatcagac ggtttggatc aaccagtttg gtaataagaa acagggaggt gggagagaaa
     3181 attccacctc ttgcttttgt atagagtata gattgtaaag aagactattc gttcatagaa
     3241 aggtagagag aatatggttt ttcctagcga acaagaacag attgaaaaat ttgaaaagga
     3301 tcatgtagtc caacattatt ttgaggtttt gcgtaccttg atttctaaga aatcagtctt
     3361 tgcccagcag gttggactca aggaagtcgc aaattatctg ggtgagattt tcaagcgtgt
     3421 tggagctgaa gtggagattg atgagagcta tacagcgccc tttgtcatgg cacatttcaa
     3481 gagttcgcgt ccagatgcca agaccttgat tttctataac cactatgaca ctgtgccagc
     3541 ggatggggat caggtctgga cagaggatcc ttttacgctt tcggtccgca atggcttcat
     3601 gtatgggcgt ggggttgatg acgacaaggg tcatatcaca gctcgcttga gtgctttgag
     3661 aaaatatatg cagcaccatg atgatttacc tgtcaatatc agctttatca tggagggagc
     3721 ggaggaatcg gcttcaacag acctagataa gtatttggaa aagcatgcag acaaactccg
     3781 tggggcggat ttgttggtct gggaacaagg gaccaaaaat gccttggaac agctggaaat
     3841 ttctggtggc aataagggga ttgtgacctt tgatgccaag gtaaaaagcg ctgatgtgga
     3901 tatccactcg agttatggtg gcgttgtgga atcagctcct tggtatctcc tccaagcctt
     3961 acagtctctt cgtgctgcgg atggccgtat cttggttgaa ggcttgtacg aagaagtaca
     4021 cgagcccaat gaacgagaaa tggccttgct agaaacttat ggtcaacgaa acccagagga
     4081 agttagtcgg atttatggat tggagttgcc tctcttacag gaggagcgga tggcctttct
     4141 aaaacgtttc tttttcgagc cagcgcttaa tatcgaagga atccagtctg gttatcaagg
     4201 tcaaggtgtt aagactattt tgcctgcaga agccagtgcc aagctagagg ttcgtctggt
     4261 tccgggccta gaaccgcatg atgttctgga aaaaattcgg aaacagctag acaaaaatgg
     4321 ctttgataag gtagaattat actatacctt gggagagatg agctatcgaa gcgatatgag
     4381 cgcaccagcc attctcaatg tgatcgagtt ggccaagaaa ttctatccac agggcgtttc
     4441 agtcttgccg acgacagcgg ggacaggacc tatgcatacg gtctttgatg ccctagaggt
     4501 accaatggtt gcattcggtc taggaaatgc caatagccga gaccacggtg gagatgaaaa
     4561 tgtgcgaatc gctgattatt acacccatat cgaattagta gaggagctga ttagaagcta
     4621 tgagtagaga tattatcaag ttagatcaga tcgatgtgac ttttcaccaa aagaagagaa
     4681 ccatcacagc ggttaaggat gtgaccattc acatccaaga aggggatatc tacggaatcg
     4741 ttggatattc tggagcaggg aaatcaaccc ttgtacgggt gattaacctc ttgcaaaaac
     4801 catctgcagg gaaaattacc attgacgacg atgtgatttt tgatggtaag gtcaccttga
     4861 cggcagagca gttgcgtcgt aaacgtcaag atatcgggat gattttccag cattttaacc
     4921 tgatgagcca aaagacagca gaggagaatg tagcctttgc ccttaaacac tctggactca
     4981 gcaaggaaga aaagaaggct aaagtagcta agttgttgga cttggttggt ttggcagatc
     5041 gtgctgaaaa ctacccttca caactatctg gagggcaaaa acagcgtgtg gcaattgcgc
     5101 gtgccttggc caatgatcca aaaatcttga tttcagacga gtcaacttct gcccttgacc
     5161 ctaagacaac caagcagatt ttgaccttgt tacaagattt gaaccaaaaa ttaggattga
     5221 cagttgtctt gattacgcat gaaatgcaga ttgtcaaaga cattgccaac cgtgtggcgg
     5281 ttatgcagga tgggcatttg attgaagagg gaagtgtcct tgaaatcttc tcagacccta
     5341 aacaaccttt gactcaagac tttatctcaa cagccacagg tattgacgaa gccatggcca
     5401 aaatcgagaa gcaagaaatc gtggaacact tgtctgaaaa cagtctcttg gtgcaactca
     5461 agtacgctgg agcttcaaca gacgagccac ttttgaatga attgtacaag cattaccaag
     5521 taatggctaa tattctctat gggaatatcg aaattctcga tggtactcct gttggagaat
     5581 tggtggtggt cttgtcaggt gaaaaagcag cgttggcagg tgcccaagaa gccattcgtc
     5641 aagcaggtgt acaactaaaa gtattgaagg gagtacagta agatggaatc attgattcaa
     5701 acctatttac caaatgtcta taaaatgggt tgggctggtc aggcaggctg gggaacggct
     5761 atctacttaa ctctttatat gacagttctt tccttcatta tcggaggctt cttggggcta
     5821 gtggcaggtc tctttctcgt cttgacagcg ccaggtggtg tcttggagaa taaagtcgta
     5881 ttctggattt tagacaaaat tacctcaatt tttcgtgcgg ttccctttat catcctcttg
     5941 gcaatcttgt caccactttc tcacttgatt gttaaaacaa gtatcgggcc aaatgcagcc
     6001 cttgtcccac tttcttttgc agtctttgcc ttctttgccc gtcaggtgca ggttgtcttg
     6061 gctgaattgg atggcggtgt cattgaggcg gctcaagcga gcggagcgac tttctgggac
     6121 atcgtgggtg tttacctatc agaaggtctt ccagatttga tccgtgtgac gactgtgacc
     6181 ttgatttccc ttgttgggga aacagctatg gccggtgcgg ttggagctgg tggtatcggt
     6241 aacgtagcca tcgcttatgg atttaaccgc tacaatcacg atgtgaccat cttggcaacc
     6301 atcattatca ttttgattat ctttgcaatc caattcttgg gagatttctt gactaagaaa
     6361 ttgagccata aataaaaaag agccgtgtgg ctctttttaa ctgatcagat tttctgtgca
     6421 aattttttac tcaaggcttg tccaatcaag gcacccacta gggctccgat gacaatactt
     6481 gcgataaata gaaggacagt tccaggggtt ggagcgacca tgatacggtc gatatattct
     6541 tgggattttc ctcttgccag aagagtagcc atataggctt tgggcgcaat ccacataagc
     6601 aagattggtc ctgttgtact aaaggcgaaa ataatgaaag aaaggaagtt ctttgttttg
     6661 tccttgtatt ttcctaaatg agctacttca tctgctagga ggccacagat aattccagga
     6721 aggaaggaac cagcaccgtg tttagttccc aagaaaaaga aggcaatgac aaggccgata
     6781 gtggtaatgg ctccaaagcg cggaactttt gcgactagga tcatatagac gctaccgccg
     6841 acaagggcag taaaggcagg cgcataaaac atgtttccag tttggtcaaa gagattgccc
     6901 aaaaggacac caatccccat gcagaggaag taaagaactg caaaaagcag tgtagttaag
     6961 atagattttt tcatgaattg tctcctgata attttttcac aattctcatt gtaccacggt
     7021 ttggtgggat tgtaaatgga tactagaagt ttttgaaaac gcttgaaata tgatataatg
     7081 gtttcatagt tatttttagg ggaatatcat gggtagattt ttagactttg tctttaatcg
     7141 tttcttttta gggatgattg cgacagcctt cttttggcta ttaactttag caggagggat
     7201 tatccttggt ctagcgccgg ctagtgccac cttgatgagc ttatatgcag aacatggtta
     7261 tagctttcgg gaatacagtt tgaaggaggc ttggtctctt tacaagcaaa attttgtctc
     7321 aagcaacctg attttctata gctttttagg tgtgggtcta gttttgacct atggtttgta
     7381 tctcttggtg caattgcctc atcagaccat tgttcatttg attgcgaccc ttttgaatgt
     7441 cctagtagtt gccctgatct ttttggctta tacagtatct ttaaaattac aagtttattt
     7501 tgccttgtcc tatcgaaata gtctcaaatt atccttgatt ggcatcttta tgagtctagc
     7561 agctgtggct aaggttctcc ttgggactgt gctacttgta gcaattggtt attatatgcc
     7621 tgccctgcta ttttttgtag gaattgggat gtggcatttc tttatcagtg atatgttgga
     7681 acctgtctat gaaatcatcc atgaaaaatt ggcgacaaaa tagaatgaag cagttttggc
     7741 tacatacgct tctaagaacc tatagttcag tgatgatcat tatcattgcg agttttgcaa
     7801 tcttactctc ttacgctgac tgggattcac gtgaaaagga agcccagaga gtagcccagc
     7861 gtgtaactgc tagaacagtg agtgaaattg aatattacca tagagagtca acccagatag
     7921 ctcaggcttt agttgaaaat caagctcgta tcgagggaat ctataaatac tttagcctta
     7981 gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat atatcagtct
     8041 ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact ggggtggcca
     8101 ttgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt agtggagaaa
     8161 aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg gtgtcagatc
     8221 cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct gttttatacc
     8281 atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc tcaccttttg
     8341 atacggagat ttttcatatt ggtgagacag ttgataggga gagtgaaaat tggctagttg
     8401 gcttaacttc tcatggatat caggttcagg tggcagttcc taaaaacttt gttttacaag
     8461 gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt gtcattcttt
     8521 atctgacttt gaggcagact tttgctaatt accaaaagca ggtagtggat ttagtggaat
     8581 ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc gaaaaagatc
     8641 aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg gaaaagaata
     8701 tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga gccttgcagg
     8761 cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg tatgcagtta
     8821 tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc ttgcgtaaca
     8881 atatttccga cgaaagagag accctcctca aacaggaatt agaattttgc cgtaaataca
     8941 gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag atagatccag
     9001 agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa aactatttcg
     9061 cgcatggtgt tgaccacagg aggacagata atgtcattag catcaaggct cttaaacagg
     9121 atgggtttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct gaaaagttgg
     9181 caaatatccg agaaaaatta agtcagagat attttgaaca ccaagccagc tacagtgatc
     9241 aaaggaagtc tatcggaatt atcaatgtac acgagcgttt tgtgctctat tttggagacc
     9301 gctatgccat tactatagag tctgcagagc aagccggtgt tcagtatcgt attacaattc
     9361 aagatgagta gaaagggaga aaatgtataa agtattatta gtagatgatg agtacatggt
     9421 gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gatatggagg tcgtcgcaac
     9481 agccagtcat gccgatgaag ctctagaata tgttcaggaa aatcctgtcg atgtcatcat
     9541 ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga tgaaagagat
     9601 cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt atgtaaaaag
     9661 agcaatgaac cttagtgtgg tggactattt ggtcaaacct gttgataagg tagagctggg
     9721 aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa gtcagactct
     9781 tagtcaagaa ttagacgagg ctggatttgt tagttattta ggggataagg agaattggtg
     9841 gataggtcta tccaaggaaa aacaaggttc cttcaccatt ccctactatg tcttgggcca
     9901 agactggcag attttcattt ctgaccaacc cctagatggt ttagtcgtta caccttttga
     9961 agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaaa ccctctttta
    10021 cggttctgta aatttgcagc agtctgagag tctctttgcc tattacgaac cgatttatag
    10081 ggttatcatt cagggaaatc tcaatcaaat cgtagaagag ttaaatctct tggagaaggt
    10141 agttcttgaa aatacgccgc gtgttccgat tactaaacag ctttttattc agtttgtcat
    10201 ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca tcgtcaaaac
    10261 cattcatgct attcaatcct tcgatgaatt ggttccttat atcaaggaaa ctctgaccag
    10321 ctttttcggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag tcattggtcg
    10381 tgattaccaa aaagagcttt ccctcaagga tatcagtaag gctctcttta tcaatcctgt
    10441 ctatctaggg cagttgatta agcgtgaaac cgattcgact tttgcagagt tactaaacaa
    10501 acaacgtatt aaggctgccc aacaactttt gctttcaact agtgacagca tcgaagatat
    10561 ttgttatgct gttggttaca gtaaccttgg atatttctat aaagttttcc gaaaattgtg
    10621 cggaaaatcg ccaaaagcct accgaaaaca ggtagaaact atactataaa atttgtattc
    10681 ctttacaaaa ggtgctataa tattatcagg aggttctatc atgaaaaaga aaccaattta
    10741 tctatggatc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt ttggaattgt
    10801 gagtcccttg cctagtaaag aagcccttcg tgctgctcag aaacaagttg caggggtcaa
    10861 tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag catctcattc
    10921 tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag cgattgtctt
    10981 ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg ttttgttagc
    11041 tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt tggttcaaga
    11101 tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt tctatatcgt
    11161 catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac agaaagcctt
    11221 ggcagaagaa gaggaaacag aagagcttgc ctaagtattg acaaaaaaga actatcaaga
    11281 tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca tatgaagaca
    11341 atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa
    11401 gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat caaggatttg
    11461 gtcaaggaag gcaaaaattt ctatgaaatg gaccatccct atgtcgcttt tttgccgacc
    11521 tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac gacaccggtg
    11581 ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt tgggtcagga
    11641 aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca acgctttggc
    11701 ttccctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca
    11761 gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat gaaaatcaaa
    11821 gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt tgcagataga
    11881 gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagag atggttgaag
    11941 ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc ataagttcag
    12001 gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa ttttctcttg
    12061 aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg
    12121 cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt
    12181 tgagccaaga aggaagattt ttgttttcac gcgttaccaa ggcgtaattc aaaagagcaa
    12241 agaaaggtgt tgtcaggaaa gatccaatca tggcaaagcg gagcatggtt gaaacctgac
    12301 cagcgaagaa cttgataatg acgataccga tgatagcagt gatggtcatc cagatgttca
    12361 aagatttacg attgtcctct ttttgactga ttagcagtcg gagagattcc tgattaacgc
    12421 gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag gcaataaagg
    12481 taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg aattgagaga
    12541 tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc agtgctccca
    12601 gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta aagtcaaaca
    12661 gagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa agtgaattga
    12721 tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg aagggcagag
    12781 ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga tgcttgaccg
    12841 ccgcaatgat aactgccaga acagtcgcaa tggttaaggc agacataatc catttgacca
    12901 tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa
    12961 tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg atgatagctg
    13021 agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg aggataaaga
    13081 aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc tttccagtat
    13141 cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg gctaagatga
    13201 ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat acaatgtggg
    13261 aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt agcttgcttg
    13321 cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct ttttgaattt
    13381 tcagaataat ctgtatatgt aatctatatt ctacaaaaaa ttttggaaaa atgcaagagt
    13441 attttgaaaa aagatagaaa atttacaaag aagatctgaa ataactatta tgatatagcg
    13501 gattgaaact agaatagtac acctttgctt ctaaaacatt gttagaaatc tatttgactg
    13561 tcctgatcga tttatcctgt tcttatttca tttcactata gtaaggtgca gcaggataaa
    13621 gaaaaaccga gaagtttctt tctcggattt gcttattatg aggttcctat tttctatgct
    13681 ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga atagcccaga
    13741 tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc cagtggaaag
    13801 ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg aagaaatgag
    13861 tcagagtggc acgaagcatg ctccagtcac ggctgaataa gcggttgcca aagttgaaga
    13921 gcataccgat ggctgcccag ataagtgtgc agtagagcaa gaccagggca ccgtgaacct
    13981 gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg taggtatttg
    14041 gtgcataaat gagtgaaaag aggatggaga ggatgaggcc gataagaaca ccggcagctg
    14101 catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt ttagataacg
    14161 gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac cgtttggcgt
    14221 gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa tttggataaa
    14281 attggttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt aggtctgact
    14341 cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct tgccaatctc
    14401 aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt ccagattttc
    14461 tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga caatcagctt
    14521 ttcctcctcg taagtctcac taatctgtag ttctactttc ataaatttct ctccttgttt
    14581 ttcatacaaa attaatctca cttcttgtac acctttatta atactcttca aaaatctctt
    14641 caaaccacgt cagcgtcgtc ttgccgtagg atagttgttg actttgtcag ttttatctac
    14701 aacctcaaaa cagtgttttg agctgtctgc gtctagcttt ctagtttgct ctttgatttt
    14761 tattgagtat accactattt tactccctct ggcaagggac tttgtctatg tggagggatt
    14821 gggctcctat gtggtggagt ttttctgttc tttctgaaat atggtataat agcactaatt
    14881 aatttctagg aaaatagata cagaaagggg ctgaaagatg tctcatatta ttgaattgcc
    14941 agagatgctg gcaaaccaaa tcgcagctgg ggaggtcatt gaacgtcctg ccagtgtggt
    15001 taaagagttg gtagaaaatg ccattgacgc gggctctagt cagattatca ttgagattga
    15061 ggaagctggt ctcaagaagg ttcaaatcac ggataacggt catggaattg cccacgatga
    15121 ggtggagttg gccctgcgtc gccatgcgac cagtaagata aaaaatcaag cagatctctt
    15181 tcggattcgg acgcttggtt ttcgtggtga agccttgcct tctattgcgt ctgttagtgt
    15241 cttgactctg ttaacggcgg tggatggtgc tagtcatgga accaagttag tcgcgcgtgg
    15301 gggtgaagtt gaggaagtca tcccagcgac tagtcctgtg ggaaccaagg tttgtgtgga
    15361 ggatctcttt ttcaacacgc ctgcccgtct caagtatatg aagagccagc aagcggagtt
    15421 gtctcatatc attgatattg tcaaccgtct gggcttggcc catcctgaga tttcttttag
    15481 cttgattagt gatggcaagg aaatgacgcg gacagcaggg actggtcaat tgcgccaagc
    15541 aatcgcaggg atttacggtt tggtcagtgc caagaagatg attgaaattg agaactctga
    15601 cctagatttc gaaatttcag gttttgtgtc tttacctgag ttgactcggg ctaaccgcaa
    15661 ttatatcagc ctcttcatca atggccgtta tatcaagaac ttcctgctca atcgtgctat
    15721 tttggatggt ttcggaagca agcttatggt tggacgtttt ccactggctg tcattcacat
    15781 ccatatcgac ccttatctag cggatgtcaa tgtgcatcca actaagcaag aggtgcggat
    15841 ttccaaggaa aaagaactga tgaccctggt ttcagaagct attgcaaata gtctcaagga
    15901 acaaaccttg attccagatg ccttggaaaa tcttgccaaa tcgaccgtgc gcaatcgtga
    15961 gaaggtggag caaactattc tcccactcaa agaaaatacg ctctactatg agaaaactga
    16021 gccgtcaaga cctagtcaaa ctgaagtagc tgattatcag gtagaattga ctgatgaagg
    16081 gcaggatttg accctgtttg ccaaggaaac cttggaccga ttgaccaagc cagcaaaact
    16141 gcattttgca gagagaaagc ctgctaacta cgaccagcta gaccatccag agttagatct
    16201 tgctagcatc gataaggctt atgacaaact ggagcgagaa gaagcatcca gcttcccaga
    16261 gttggagttt ttcggacaaa tgcacgggac ttatctcttt gcccaagggc gagatggact
    16321 ttacatcata gatcagcacg ctgctcagga acgggtcaag tacgaggagt accgtgaaag
    16381 cattggcaat gttgaccaga gccagcagca actcctagtg ccctatatct ttgaatttcc
    16441 tgcggatgat gccctgcgtc tcaaggaaag aatgcctctc ttagaggaag tgggcgtctt
    16501 tctagcagag tacggagaaa atcaatttat tctacgtgaa catcctattt ggatggcaga
    16561 agaagagatt gaatcaggca tctatgagat gtgcgacatg ctccttttga ccaaggaagt
    16621 ttctatcaag aaataccgag cagagctggc tatcatgatg tcttgcaagc gatctatcaa
    16681 ggccaatcat cgtattgatg atcattcagc tagacaactc ctctatcagc tttctcaatg
    16741 tgacaatccc tataactgtc ctcacggacg tcctgttttg gtgcatttta ccaagtcgga
    16801 tatggaaaag atgttccgac gtattcagga aaatcacacc agtctccgtg agttggggaa
    16861 atattaaaag tataaaaaag tctgggaaaa attttcaaaa tcagaaaaac gcataaaatc
    16921 aggtgttcaa aaaccttgat tttatgcgtt ttatcatgga aatagttact tcatgttttc
    16981 ctaattcttt tcgaaactct ttttaaacca cgtcagtttt atcagtaatc tcaaaacagt
    17041 gttttgagct aattttgcca gttttgtctg taacatcgaa gttgtgtttg accactctgc
    17101 gactggtttc ctagtttgct ctatgatttt cacagagtat taaattgcga ttttgccaag
    17161 tttctttatt cgtctaaaag tagagtctgt tctatgcgtc taatgtacga attaggttga
    17221 ccatttcaat agctccttgt gcacactcag aacccttatt tcctgcttta gtgccagctc
    17281 gttctatggc ttgttcaatt gtatctgtcg ttagcacacc aaacataaca ggaatttcgc
    17341 tatttaaact gatttgggcg attcccttag atacctcgct acatacataa tcataatgac
    17401 ttgtattccc tctaatgaca gctcccaagc agataattgc atcatatttt ttactttttg
    17461 ccatttttga tgcaatcagt ggtatttcaa aagctcctgg aacccaggct acctctatat
    17521 ctttctcgtt tacattctct cttttgagat tatctagtgc tccagataat aattttgaag
    17581 ttataaattc attaaatctc gctacaacaa tacctatttt aatattgttt gctactaaat
    17641 taccttcata agtgttcatt tatttttcct ccatatttaa aatgtgaccc attcgatttt
    17701 tctttgtttc taaataaaaa ctatcgtaag gattggcttc tatttcgatt gatattctac
    17761 tggaaatggt aattccatat ttttctaact gttcaacctt gtcaggatta tttgtcagta
    17821 aatgaagtga ctgaagtccc agatctttaa gcatttgtgc tccaatatga tattctctta
    17881 aatcaccttc aaagcctaat gcaagattgg catcaagcgt atccatgcct tgatcttgta
    17941 aatgataggc ttttaattta ttgataagtc caattcctcg tccctcctgt cgcaagtaaa
    18001 gtaagacacc cgaaccattc tcaacaatca ttttcatagc tttatcgaat tgctgtccac
    18061 aatcgcaacg taaggagcct aaaacatccc ctgttaaaca ttcggagtgg acccgacata
    18121 atacattggc ttcatcctct atgtttccca taataagagc aagatgatgt tccccattta
    18181 gtttatctat atagctaatt gctttgaaat taccgtatct agtaggcata ttgacagttg
    18241 aaactcgttc taccagctga tcatatactt ttctatattc ttgtaattct ttgatggtaa
    18301 ttagtggaat gttgtgtttc ttcgagaact gaattaaatc atctgttctc atcattttgc
    18361 catcatgatt cattatttca caacataggc cacactcttt tagtccagct aattttaata
    18421 aatcaacagt tgcttctgtg tgtccacttc tttctagaac accacctttt tttgcaatta
    18481 aaggaaacat gtgtcctggc ctgcgaaaat cagagggtgt tatatcttca gctacacaca
    18541 tacgtgcggt cagtcctctt tcctcggcag aaatacctgt ggtcgtttct ttataatcaa
    18601 ttgaaactgt aaaagcagtc ttatgattat ctgtattgtt ttcaaccata ggtgaaagca
    18661 ttaattgatt agctaaactt tcgctcatag gcatacaaat taatcctttg gcataagtag
    18721 ccataaaatt aacattttct gttgtagctg cttgtgcaga gaaaattaag tctccttcat
    18781 tttctctatc cttgtcgtct ataacaagaa caagtcgtcc cttctgcaat gcttctaatg
    18841 cttcttgtat ttttcgatat tccattgact gattatcctt tctgctaaaa tccattttga
    18901 tataatagtt ccttagatat ttctgatttt ggagagttat ccatcagttt ttgcacatat
    18961 ttacctaaga tatcattttc aagatttact gtactcccga cttgtttact cttaagaatg
    19021 gtttgttcca aggtatgagg gataacagat actgaaaagt ttactttgga gactttagcg
    19081 acagtcagac taatgccgtc aattgtaata gatccttttt caactattaa atctaaaatt
    19141 tctttttgtg tgttgatttg ataccataca gcattatcat ctttttttat tgacgagatt
    19201 tttcctgtac catcaatgtg tcctgtaacg acgtgacccc caagtcgacc gttgacagat
    19261 aaggctcttt ctagattcac ctcacttcca tgttttaata gagtaagagc tgttcgactc
    19321 catgtttcat tcattacatc aactgtaaag gattgatgat tgaaatgagt aactgtaaga
    19381 cagataccat ttactgctat actatcgcct aaatggatat ccgttaatat ttttgaggct
    19441 ttaattgata gtttacaatt acgagagtct ttctgtattc tttcaacttt tccgatttct
    19501 tcaattattc ctgtgaacat ggataaatca cttcactttc tatgagatag tcatttccta
    19561 tttgagaaaa tgcataaggt ttcaatctaa tagcgtcatt tggcaaagaa ataccttcac
    19621 ctccgacagg aaacttggca ctacctccaa aaatttttgg tgcaatatat attttcagct
    19681 catcaacaat ttgttgttcc aaagcactcc aattcattag actgccccct tctagaacta
    19741 ggctatcaat ctgcatgttt cctagatgtt gcattaaact cgataagtct atatgattgc
    19801 cttttttctt tatggaaagt atttcacagc catgattttg atatagcttc attttatttt
    19861 tgtcttcaga ggaagtggca atgtaagttt taatatcatt tgctgttttt acgattttag
    19921 aggtaagagg agttcgtaaa tgtgtatcgc atatgatacg gataggattt ttcccttcct
    19981 ccaatctaca tgtcagcaaa ggatcgtctt gaataacagt attgactccc accataattg
    20041 cactaacatg gtgtcgtaac tgctgcacat gctttcttgc ttcttcttca gtaatccatt
    20101 tggattgatt tgttttagtg gctatttttc catccattga cattgcatat ttcataaaaa
    20161 catagggtac atgctgggta atatactttc taaaactttt tattaagtta agacactcat
    20221 tttctaaaat tccaacagta acttgaagat tattttcctc aagtatcttt actccttttc
    20281 cagatacaat aggattacag tctaggcttc caatgactac tcttgtaata ccactatcga
    20341 ttatagcatc tatacaggga ggtgttttcc cgaagtgaca acagggttca agtgttacat
    20401 aaagcgtcgc tccgacaggg gattctctac agtttttaag agcatttctc tcagcatgtg
    20461 ggccaccaaa aaactcatga taaccttgtc cgataatgtg attatctttt acaataactg
    20521 cgccgaccat aggattggga ttgacgtaac cagccccttt ttgtgccagt tttattgcta
    20581 atttcatata ttttgaatcg ctcatctcac tacctccaaa aaaatatgcc ttgaataggg
    20641 gactactcaa ggcatacaaa agaaaactta tgcgattaac aaaaatgctc tgaaatgaca
    20701 agtaatcatt tcagagcacg caaaaagcac aaatatactt ttatcttctt tcatccagac
    20761 tatactgtcg gctttggaat ttcaccaaat catgcctttc ggctcgtggg ctataccacc
    20821 ggtagggaat ttcaccctgc cctgaagata gttattcaat tacagatgat tatagtactt
    20881 aattttgaat atgtcaacag ataaataccg attgtttttg atatactgta tttgtgataa
    20941 tcgattctcg ctcctcggat aaagaaaata tgatatacta gataaacgaa ataagagaga
    21001 aggaatacta tgtacgcata tttaaaagga atcattacca aaattactgc caaatacatt
    21061 gttcttgaaa ccaatggtat tggttatatc ctgcatgtgg ccaatcctta tgcctattca
    21121 ggtcaggtta atcaggaggc tcagatttat gtgcatcagg ttgtgcgtga ggacgcccat
    21181 ttgctttatg gatttcgctc agaggatgag aaaaagctct ttcttagtct gatttcggtc
    21241 tctgggattg gtcctgtatc agctcttgct attatcgctg ctgatgacaa tgctggcttg
    21301 gttcaagcca ttgaaaccaa gaacatcacc tacttgacca agttccctaa aattggcaag
    21361 aaaacagccc agcagatggt gctggacttg gaaggcaagg tagtagttgc aggagatgac
    21421 cttcctgcca aggtcgcagt gcaagcaagt gctgaaaacc aagaattgga agaagctatg
    21481 gaagccatgt tggctctggg ctacaaggca acagagctca agaaaatcaa gaaattcttt
    21541 gaaggaacga cagatacagc tgagaactat atcaagtcgg cccttaaaat gttggtcaaa
    21601 taggagcaga gaatgacaaa acgttgttcg tgggtcaaga tgaccaaccc gctctacatc
    21661 gcctatcatg atgaggagtg gggccagccc ctccatgatg accaagtatt gtttgagttg
    21721 ttgtgtatgg aaacctatca ggcaggcctg tcttgggaaa cggtactcaa caaacgccaa
    21781 gctttccgag aagtctttca tagctatcaa attcactcag tcgcagagat gactgacact
    21841 gaattggaag ccatgctgga gaatccagct atcattcgaa atagagccaa gctttttgct
    21901 acacgcgcta acgcccaagt ctttctacag ttacaggcag agtacggctc ttttgatgcc
    21961 tatctttggt cttttgttga ggggaaaact gtcgttaacg atgttcctga ttatcgccaa
    22021 gcgccagcta aaacaccctt atctgagaaa ttagccaaag atctcaaaaa acgaggcttc
    22081 aagttcatag gcccagtcgc cgtattgtct tttctacagg ctgcagggct agttgatgac
    22141 cacgagaatg attgtgagtg gaaaggtctt aaatgatgtc taacaaaaat aagggaattc
    22201 tgatttttgc gattctctat acagtcctct ttgtgtttga tggcgttaaa ttgctggctt
    22261 ctttaatgcc atctgtcatt gcaaattatc ttgtttatgt agttttagct ttatatggct
    22321 ccttcttgtt caaggataga ttgatccaac aatggaagga gattagaaag actaaaagaa
    22381 aattcttctt tggcgtctta acaggatggc tctttctcat tctgatgact gttgtctttg
    22441 aatttgtatc agagatgttg aagcagtttg tgagactaga tggacaaggt ctaaatcagt
    22501 ctaatattca aagtaccttt caagaacaac cactactgat agctgttttt gcttgtgtca
    22561 ttggacctct ggtagaagaa ttatttttcc gtcaggtctt attgcattac ttgcaggaac
    22621 ggttgccagg tttactaagc attattctgg taggacttgt ttttgctttg actcatatgc
    22681 acagtttggc tctatcagag tggattggtg cagttggtta cttaggtgga ggccttgcct
    22741 tttctattat ttatgtgaaa gaaaaagaga atatctacta tcccctactt gttcacatgt
    22801 taagcaacag cctctcctta atcattttag ctatcagtat agtaaaatga aataagaaca
    22861 ggacaaatca atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
    22921 ctattctagt ttcaatacac tgtaacatgt gatgaaaatg ccagtaatga taccgagaaa
    22981 aaagctgaga aacttttccc agctttattt gttatagtca aagcgaatga cttgttcctg
    23041 tgcatctaca tgagcatgga ccccaaaggg tacaattgct cttggagttg cgtggccgac
    23101 attcagatta tagacaatcg ggatattgct gtcaatgata tccaatagtg cctctttata
    23161 gtcgtcatgg aaagtttcat ccataggttt tccgaccaag agtccattga tgaccgcgaa
    23221 tatgccagtg tcctttaaag ttagcaacat ctttttgaag tcttctggct taggcttttc
    23281 ttcgcttgtt tcgagcaaga ggattttccc ttcccagtct gacaagtcag ggaaaagttt
    23341 gtattttggg cagagttccg tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag
    23401 ggattctagg caaccaccga ggattttccc ctcgaactga gcacttcctt gcaacaagtc
    23461 aaaacctgta tttgtatgac tgacacgagg tgttcccagg gccgtgggac taaaatcagt
    23521 tcgttcctca taccaaacgt cactagggcg gatttctgaa attcttcccg tctcaatcaa
    23581 ttctttaaag tagtgaaggc tataggctag catttctttg tctaattcac aaatgtctgc
    23641 taaaaaggat tgaccataaa aagtcttgat tcctaattta tgcaacatga ggtggttcat
    23701 ggttgtatcc gagaagccaa gaaaaatttt ttgcttgata accttttgga gttggtcatt
    23761 ttcaaaaaga taaggtagca agcgataggt atcgtctcca ccgatggcac ataggatcat
    23821 gtcgatgcta tcatcagaaa aggcatgaat caaatcctct gcacgagctt caggatggtc
    23881 cttgataaag tctaatcctt ttaacgaatg gggcaaaaag atgggattga gtcccagatc
    23941 cttgagacgt tggataccca agtccacttc gtgtttgaca aaatcctctc cgataatgcc
    24001 actagataaa ctaacaatac caatagtaga aaccatatct catcctccta gaaatagatt
    24061 gagcctattt tatcacaaaa tataagagaa agctatgtgg gatttcagaa gaatactttt
    24121 aatactcttc gaaaatctct tcaaaccacg tcagttttat ctgcaacctc aaagctgtgc
    24181 tttgagcaac ctgcagctag cttcctagtt tgctctttga ttttcattga atataactca
    24241 aaaaagtaag tgaaaaagca accgcacctg cagttgcttt tatcgttttc ttattcttga
    24301 tagcgtgttg gtcctgcact tgcactacgg atattcaagc gtttcttgag atagaagcga
    24361 agggctagga gggctgctcc aataatagct agtggcaatg gatccagtac tgggttaagg
    24421 ctagctggta ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat agaagctagg
    24481 ataactagta cagatttcca gaaaggtgga cgttgactgc gatccatatc tggtccatag
    24541 tattggtaaa caaagtagta catcaagtag aaggcaaatc caccaaccag tccaactaat
    24601 agaagagtaa tcaatccata gccgaaagct tggtctgccg caaagaaggt tgtgagggcg
    24661 ctgacaaggg caaagaggct agtgatgaaa agagctgagt ccataatcat cagttttggg
    24721 tcatcatttt cttttggatg ctctttttcg tactgctctt tgacagtgaa gctatgagcc
    24781 caatgagttg gtgcgccgta tagggaacgg gcagttgtac ctttagattg ctcctcaagg
    24841 atttggggaa tgacttcctc aaaaatagtc tggatttcag cgtctgtttt cccatctttg
    24901 atgaattgtt gggtagcaat gtggacaaac tcttggtttt tcttagttaa tttttgtaga
    24961 tcaatttgag acataggaac tcctcttaga accatttttt atggatgaga tagagagtga
    25021 gcgagacact catagcaaag gcgataaaga cgattaacca gaaggcattt ggctctccgt
    25081 ttagggggat ttcattatcc ttaaagttca tcccgtaggc agaaaagacc atggttggga
    25141 tggacatgac gatggtcaca agggccaagg ttttcatgat gttgttctgg ttgttagaaa
    25201 tgatagaggc aaaggtctct gtcatagaat gcaagacgtt tccataaata tctgccatct
    25261 cgatggcctg ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc tcaaggtatt
    25321 tcttgatatt gctggttgaa ctggtcaatt tcttaatcac gcgctcattt gttttgaggg
    25381 aggccttgaa atagacgata gttttttcca attccatgag ctcaatcaat tcttcattac
    25441 gagttgattg atgcagttga ctttcgattt gttcactctt gcggtcgatt gaacgaaggg
    25501 ctgttaggta aagctctgca ttgcgataaa gaatttgaaa gataaaacgt gaacgcatga
    25561 aggtatagaa attacgcaat cgacggttga taaagacatc aaggacaggt agtggttcca
    25621 aacacgtagt gataatggtt tcctcagtga tgataatacc aagcgggatg gttacgtagt
    25681 aggtgcggtt atttctttcc tccgtgaccg gcacgtctac gataatcagg gtatactcgt
    25741 cttcaatggt aatacgagac atttcttccg catcgagcgg tgctcgaagg tcggcaatat
    25801 caatatcgaa ggtgttggcg atttcgagtg attcattttg agtcggattg acgagattga
    25861 tccaagtacc cggttcaagc gtatcgatct ctttaaattc agttgttgta gagagaaaaa
    25921 cttgtttcat atcccttatc ctttctcatt tttcagattt tttcacactg tactattata
    25981 ctacaaaatc ggccttttgg gtaatagaat ctcacttttt ttggtataat ggtaagcaat
    26041 aatggactag aaagaacaaa gatgcaagat aaaattgtca ttcatggggc gcgtgcccat
    26101 aatttaaaaa atattgatgt ggagattccg cgagacaagt tggttgtcgt gactggcttg
    26161 tcaggttcag ggaagtccag tctggctttt gatactctct atgcggaggg acaacgtcgc
    26221 tatgtagaga gtttgtccgc ctacgctcgt cagttcttgg gaaatatgga aaaaccagat
    26281 gtagatgcca ttgatggtct cagcccagct atttccatcg accagaaaac gactagtaaa
    26341 aatcctcgct cgacggtggg aacgacgact gaaatcaatg actatctgcg tctcctctac
    26401 gcacgtgtgg ggacgcctta ctgtatcaac ggacatggag ctatcaatgc ttcttctgtg
    26461 gagcaaatcg ttgataaggt tttggagtta cctgaacgcc agcgcttgca gatcttggct
    26521 cctgtcatcc gcaagaaaaa aggccaacat aagagtgtta tcgagaaggt tcagaaagac
    26581 gggtatgttc gtgttcgtgt ggatggggaa gtctatgatg tgaccgaagt gccagagttg
    26641 tctaagagca agcaacacaa tatcgatgtc gtggttgacc gtattgttat caaggagggc
    26701 attcgtagtc gtctctttga ttccattgag gctgcccttc gtattgcaga aggttatgtc
    26761 attatcgaca ccatggacga ttcggagttg ctcttctctg agcattatgc ctgtccagtt
    26821 tgtggtttta ctgtcccaga gttagagcct cgtctcttct ctttcaatgc tccttttggc
    26881 tcttgtagtg agtgtgacgg cttgggcatc aagctggagg tggatactga tttggtagtg
    26941 ccagatgcca gcaaaacctt acatgaggga gcgctggcac cttggaatcc tatctcatcc
    27001 aactactatc caaacatgtt agagcaggcc atgaaagtct ttggagtggc tatggataag
    27061 ccttttgagg acctgtcaga agaagataag aacttgattc tctacggctc agatggtaag
    27121 gaattccatt tccattatga aaatgaattt ggtggtgtgc gcgatatcga cattccgttt
    27181 gagggagtta tcaataatat caaacgtcgt taccatgaaa ccaatagcga ttacactcgc
    27241 actcagatgc gtctctacat gaatgagctg acctgcggaa cctgtcaagg ctatcgtctc
    27301 aatgaccagg ccttgtctgt ccgtgtgggc ggccagcaag ggccacatat tggagaaatc
    27361 tcagacctgt ctatcgctga ccacttggac ttggtgagcc agttaacttt gtctgaaaat
    27421 gaagccatca ttgctcgtcc cattctcaag gaaatcaagg atcgtttgac cttccttaat
    27481 aatgtgggtc ttaactatct aaccctgtca cgttcagcag gaaccctttc aggtggggaa
    27541 agtcagcgca ttcgtttggc aacccagatt ggttccaacc tatcaggtgt cctctatatc
    27601 ctagacgagc cgtcaatcgg tcttcaccag agggacaatg accgcctgat tgccagtctg
    27661 aaaaagatgc gtgacttggg caatactctt atcgtggtgg aacacgacga agataccatg
    27721 cgtgaagctg attatctgat tgacgttggt cctggtgccg gtgtttttgg tggtgagatt
    27781 gttgcagcag gtacacctaa gcaagtggct cgcaacagca agtctatcac aggtcagtac
    27841 ttgtcaggca aacgtgtcat cccagtacca gaagagcgcc gtgtcggaaa tggtcgtttt
    27901 attgaagtga caggagcgcg tgagaacaac ttgcaaaatg tcacggctcg ctttccacta
    27961 ggaaaattta tcgcagtgac aggtgtgtcg ggttcaggga aatcgactct aatcaacagc
    28021 attctcaaaa aagccattgc ccagaagctc aaccgtaatt cagacaaacc tggtaagttt
    28081 aagactatta cagggattga gcatgtcgac cgtttgattg atattgacca gagccctatc
    28141 ggacggacgc cgagatctaa cccagctacc tatacaggag tttttgacga tatacgtgac
    28201 ctttttgctc agacaaatga agccaagatt cgaggctaca agaaggggcg cttcagtttc
    28261 aacgtcaagg gaggtcgctg tgaagcttgc tcaggtgacg ggattatcaa gattgagatg
    28321 cacttcttgc cagatgttta tgtggcttgt gaagtttgcc acggaacccg ctataacagt
    28381 gaaaccctag aagttcacta caaggaaaag aatatttcgc aggtcttgga tatgacggtc
    28441 aacgatgcgg tagaattttt ccaacacatt ccgaaaattc aacgcaaact ccagaccatc
    28501 aaggatgtag gtctaggcta tgtgaccttg ggacagccag ctaccaccct ttctggggga
    28561 gaagcccaac gtatgaagtt agctagcgaa ctccacaaac gctcgacagg aaaatctttc
    28621 tacattctgg atgagccgac gacagggctt catacagagg acattgctcg cctgctcaag
    28681 gttttagctc gctttgtaga cgacggcaat acagtcctcg tcatcgagca caatctggat
    28741 gttatcaaga cggcagacca tatcattgac ttgggacctg agggcggtgt cggtggtgga
    28801 accatcatcg taacaggaac tccagaagaa gtagctgcca acgaagccag ctatacagga
    28861 cactatttga aaggaaagtt acatcatgaa taaacgcgta caagcatttc tagctaaaat
    28921 gcaagaaaaa gaactagatg gtatcatcat caacaatctt aaaaacgtct attatttgac
    28981 tggtttttgg ggctcaaacg gaacagtctt tatcagccgt gaccgtcagg tcttagtgac
    29041 agactctcgc tatatcatcg cagctaagca agaaaccagt ggttttgaga ttgtggctga
    29101 tcgtgatgaa ttggctgtca ttgcaggaat tgttaaggac atgggcttga ctcgtatcgg
    29161 ttttgaagat gagatttcag tgtcttatta ccaccgtatg caggcagctt ttgcaggttt
    29221 ggacttgctt ccacaaactc agtttgtgga aggtcttcgt atgattaagg atgaggcaga
    29281 gattgcagcg attcgcaagg cttgttctat ctcagaccaa gctttccgcg atgcgcttga
    29341 ctttatcaaa ccaggaaaaa ctgaaattga gattgccaac ttccttgatt tccgcatgcg
    29401 tgagttggga gcatctggct tatcttttga tacgatccta gctagcggta tcaattcttc
    29461 taaaccccat gcccatccaa tgcacaaacc agtggagttg ggagaagcca ttaccatgga
    29521 cttcggctgt ctctatgacc actatgtcag tgatatgacc cggactatct atctagggca
    29581 tgttagcgat gagcaggcag agatttacaa tacggttcta aaagctaacc aagccttgat
    29641 tgaccaagct aaggcaggct taggtttccg tgactttgac aaaatccctc gtgatattat
    29701 cattgaggca ggttatggcg actactttac tcacggcatt ggccacggta ttggtctgga
    29761 tatccatgag gaaccctact ttagccagac ttctacagaa actattaaga caggtatggc
    29821 cttgaccgat gaaccaggta tctatatcga aggcaaatat ggcgttcgta tcgaggatga
    29881 tatcctgatt acagagacag gttgtgaatt attgacccta gctccaaaag agttgatagt
    29941 catttagttg tttgtcaaga aaaaagtacg aaaatgacga aaaaagtcaa aaaaaattaa
    30001 aaataggtcg caagtcggat gttttttatg gtataataga ctaaactgat agtaacatgt
    30061 agcgaaaggg gtaggtacat gattaaaatt tatacagtct caagttgtac tagctgtaaa
    30121 aaagcaaaaa cctggctcaa tgcccaccag ttaagttata aagaacaaaa ccttggtaaa
    30181 gaaggaatta cgagagaaga attactggat attctaacca aaacagataa cggaatagcc
    30241 agcatcgttt cgtctaaaaa tcgctatgcc aaagcccttg gagtggatat tgaagatttg
    30301 agtgtcaatg aagttctcaa tctgattatg gaaacaccga gaattttaaa gagcccaatc
    30361 cttgtagatg aaaaacgcct gcaagttggc tacaaggaag acgatattcg tgccttccta
    30421 ccacgctctg tccgtaatgt agaaaatgca gaagcacgtt tgcgtgcagc tctataaaca
    30481 tcaaggctgg gagcacttcc cagtcttatt ctattttaat ttcaaaaaga aagaagaaag
    30541 aaatgaaaaa aatagttctt gttagtctag ctttcctttt tgtcctggtt ggttgcggac
    30601 agaaaaaaga aactggacca gctacaaaaa cagaaaaaga tacgcttcag tcggcattgc
    30661 cagttattga aaatgctgag aagaatacag ttgtaactaa gactttggtc ttgcccaagt
    30721 cagatgatgg tagccagcag acacaaacaa ttacttacaa agacaagact tttttgagtc
    30781 taactatcca acaaaaacgt ccagtctctg atgagttgaa gacttatatt gaccaacatg
    30841 gagtggagga aactcaaaaa gctcttcttg aagcggagga gaaggataag tctatcattg
    30901 aagctcgtaa attggcaggt ttcaaacttg aaacaaaact attgagcgca acggaacttc
    30961 aaacaacgac tagttttgat tttcaagttc tggatgtcaa gaaggcttcc cagttggaac
    31021 atctgaagaa tattggtttg gaaaatcttt tgaaaaatga accaagcaac tatatttcag
    31081 atagattggc aaatggcgcg acagaacaat agaaaatcca aataaataga ctgcctgaat
    31141 tgtagaaggt aaggaattat gctataatgg tactattcta aggaaagagg gtgttagaat
    31201 gggatttact gaagaaacag tacgttttaa attggacgat tccaataaaa aagaaattag
    31261 cgaaactttg acagatgttt atgcttcgtt gaacgataag ggttacaacc caattaacca
    31321 aatcgtaggt tacgtattga gtggagaccc tgcctacgtt cctcgttata ataatgcacg
    31381 aaatcaaatc cgtaagtatg agcgtgatga aatcgttgag gaattggttc gctactacct
    31441 caaaggacaa ggagtcgatc tataacctat gagaattatg ggattggacg tcggttcaaa
    31501 aacggtaggg gtggcgatta gcgatccgct tggttttaca gctcaagggc ttgaaatcat
    31561 ccagataaat gaagaacaag gccaatttgg ttttgaccgc gttaaggaat tggttgatac
    31621 ttacaaggtg gaacgatttg tagtgggctt gcctaaaaac atgaacaata caagtggacc
    31681 gcgcgtagaa gctagtcaag cctacggagc aaagctagaa gagttttttg gtttaccagt
    31741 agactatcag gatgaacgct tgacaacagt ggctgctgag cgcatgttga ttgaacaagc
    31801 agatatcagt cgcaataagc gcaagaaagt cattgataag ttagcagctc agctgatttt
    31861 acaaaattat ttagatagaa aattttaata taaaggagag gctatgtcac acgatcataa
    31921 ccacgaccac gaagaacgtg aactaatcac actagtagat gagcaaggaa atgaaacctt
    31981 gtttgaaatc cttttgacaa ttgatggaaa agaagaattt ggtaaaaact atgttcttct
    32041 agtaccagtt aacgcagaag aagacgaaga cggacaagtt gaaatccaag cttactcatt
    32101 cattgaaaat gaagatggaa cagaaggcga attgcaacca atcccagaag actcagaaga
    32161 cgaatggaac atgattgaag aagtcttcaa cagctttatg gaggagtgat acagtctggg
    32221 agactgtatc agcccaactc ccagaaatgg ggaagagttg gaacgtccag tgaacatttt
    32281 taccccaact cttagaaatt gagaagagtt ggaacatcta gtggatgttt ttagcccata
    32341 ttcacattca tagtggctag ttattagcta accaggtaag aggtcgggac gaaaatcctg
    32401 gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga
    32461 gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttaa attttcgatc
    32521 aggtttgggc cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc
    32581 tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt
    32641 atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa
    32701 tgaccgaatc tgcattaatg ggcaacctat agcagacgca gactttatcc gtttggctga
    32761 tcaggtcaag gagatggaga aaacgcttct gcaaactcct gaccagttgt ccttttttga
    32821 attgctgacc ttggttgctt ttctttattt tagggagcaa gaggtggatt tggttttatt
    32881 agaagtggga attggtggct tacttgacac gaccaatgtg gtaactggag agcttgctgt
    32941 catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc
    33001 agagcagaaa gctggtattt tcaaggctgg taagaaggca gtgattgcga aattgcatcc
    33061 agaagctagg cttgtctgtc agaaaaaagc cgaatcttta gctgttaacc tttatcaggc
    33121 aggtcaagat tttttaatgc tgaatggtga tttttcaagc tctttactaa atctttcaca
    33181 gctgaacata ggcttagaag gagtctatca gcaggagaat gcagccttgg cgttgcaaac
    33241 ttttcttctt tttatgggag aaggaaagga agctgttgat gaacaggctg taagaaaggc
    33301 cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttacttgga
    33361 tggtgctcat aacctccctg ccttgactcg cttggttgag tttattaaag aaaaagagca
    33421 ggaaggttat cgtcctcaaa tcctctttgg atccttgaaa cggaaggatt atcaagggat
    33481 gttgggttat ctgactgaaa atttacctca agtggaactc aagatgactg gttttgacta
    33541 tcaagggtct ttggacgaaa gggatgtgac aggttacgat atagtttctt cttaccgaga
    33601 atttatcagc gattttgaag aaagagcaga tgctcaggat ttgctgttcg ttacagggtc
    33661 tctctatttt atctcagaag tacggggcta cctgctggat cgtgagcaga taaattgacc
    33721 cccttgtttg aacttgttat actagggaaa ttgctggtta gagaaaattt ctctaaattg
    33781 gtagcagaaa ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta
    33841 gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgct
    33901 caacaggtcc aacagcctgc tcaacagaat accaatactg caaatgcagg aggtaaccaa
    33961 aatcaagcgg ctccagtaca aaaccaacct gttgctcaac cgaccgatat tgatgggact
    34021 tatactggtc aggatgacgg agaccgtatc actttagtgg taactggaac gactggtaca
    34081 tggactgagc tcgaatctga cggggatcag aaagtcaaac aggttacatt tgattcagca
    34141 aatcaacgca tgattattgg cgatgatgtc aaaatttaca ctgtaaacgg taatcaaatc
    34201 gtcgtagatg atatggatag agacccatca gaccaaatcg ttttaactaa ataagactat
    34261 gcaagtagaa agggctggat ttttcagcct ttttactttt acctagaaaa taatcataaa
    34321 tacttgcctt ctaccgaata cctgcgttat actagtatca attacttgtt tttagcattc
    34381 aaactatcaa ggaggggata tgaaatatag gaaatttcaa ttattgatgt ccaagtatgg
    34441 ctttagtctt tcgattatgt tacttgaact ttgtcttgtt tttggtctct ttctttattt
    34501 aggacgcatg gctcccattt tatggattac tgtcctcatt ctactgagta tcatcacaat
    34561 catttcgata gtcaaccgta atacgactcc tgagaataag gtaacctggt tgttagtagc
    34621 ctttgtgcca gtatttggtc ccttgctcta tctgatgttt ggtgaaaggc gattgtccaa
    34681 aaaagaaatc aaacaactga agaagctagg ctctatgcat ttccaagaag caaatagcca
    34741 gctactaaaa gagaaattaa aagaaagtga caaggcagct tatggagtca tcaagtcctt
    34801 attgagtatg gataccaatg ctgacatcta tgatcaaact gcctctacat tttttcctaa
    34861 cggagaagct atgtggaaaa agatggtaga agatcttaaa aaggctgaga aatttatttt
    34921 cttggaatat tacattatag aagaaggttt gatgtggaat cgcatactag atatactaga
    34981 gcaaaaggta gctcagggtg tagaggttaa gatgctctat gatgatatcg gctgtatggc
    35041 tactttaaca ggagattatg cacatcgact tcgtcagctg ggcatcgagg cccataaatt
    35101 caataaagtt attcctcgtt tgacagtggc ttataataac agagatcata gaaaaatatt
    35161 gattgttgat ggtcagatag cctatactgg tggggtcaat ctggcagatg agtacattaa
    35221 ccacgtcgag agatttggtt attggaagga tagtggaatt cgcttagacg gactagcagt
    35281 aaaagccctg acacgcttat ttttgaccac ttggtacatt aatcgaggag aaattagtga
    35341 ttttgatcaa tatcatttag aaaatcattc tatcccgagt gacggtttaa ccattccata
    35401 cggaagtgga cccaagccaa tttttcgagc gcaggtaggg aaaaaagttt atcagagttt
    35461 aatcaatcaa gcaacggaat cggtctatat tacgacacct tatttgatta tagattatga
    35521 tttaacagag acaatcaaaa atgcagctat gagaggggtc gatgttcgaa ttatcacccc
    35581 ttacatacca gataagaagt tcattcagtt agtcacgaga ggagcttatc ccgaccttct
    35641 ttctgctggt gttcggattt atgagtatag tccaggtttt attcatagta agcagatgtt
    35701 ggtagacgaa gattttgcgg tggtggggac aatcaatctc gactaccgga gcttggtaca
    35761 ccattatgaa aatgcagtct tactctataa aactccttct ataagggaaa tcgcccgaga
    35821 ttttcgaaat atatttgcag attctcagga agtctatcct cattctatca aaacgagctg
    35881 gtatcaaaag cttgtaaaag aaatcgccca gctattcgcc cctatcttat aagaaatcta
    35941 gaacttagga tacaaaccag acctattttt cttgtctttt acgaatagaa agaaagagga
    36001 ggggaattca tgctaactaa ggaagaagtg aatgatatga ttgagttcaa acagacacat
    36061 ttacaccgct ttcgggaaat tgaaaccttt gtgaaactat gcaaaaaatc actcaaacag
    36121 ccatcgcaag ctgacaatcc taggactttt tgatatacta agacagataa attgaacagg
    36181 agaaacgata tgagtgtgta tggtagagta gaagaagttc ataaggagaa tcgtgaacct
    36241 ctagaatacc aaatcgaaca agaatcgcat catcgtgaat caagtcgtct tcctttggtg
    36301 aaaattttac tatggagtac gcttgtaacg gggataactc taggagtacc gctattactc
    36361 gacttaatga gtgcacaaga agtgcaggat ttttatgcag gttgggcgct tcatcagaca
    36421 gggaagattt acagcgacta ttatggaagt caaggtttgc tttattattt gctgacttac
    36481 gtgagtcagg gcggattttt ctttgccatc tttgagtggt tggccttggt agcaggagga
    36541 tttttccttt ttagatcagc ggacaccttg acagagcaag gagaccaagc tggacatctg
    36601 gtgactattt tttacatgct agttacaggt cttgcttttg gtggaggcta tgcgactctt
    36661 ttagcgcttc ctttcttatt cgcagccttt agtttagttg cggcttacct aagcaatcca
    36721 agccatgata agggatttgt acggattggg ctagctttgg caggcggatt tttctttgct
    36781 cccttatcat cgctcctgtt tattgctgta gtgagtttag gcttgttggt ctttaacctt
    36841 gggcatagac gttttgtgca tgggttttat cagtttcttg cagtggcttt aggtttttca
    36901 cttgtctttt atccaactgc ctactatagt gctgcaacag gaagttttgg ggatgcgatt
    36961 agtggtattc gttatcctat tgacagtatt cgctttgatt ttacttctaa aattttagag
    37021 aatatgtttt tttatggctt gttgtccctt ggtttgggat ttgtggtttg tatcttttta
    37081 ggtctctttc aatccaaacc ctttaaacta tacgtcattt cggttcctgc aagtcttgtg
    37141 gtaattttag gtttgatttt acttttcttt tcacaagagc ctctgcacgc ttcttatttg
    37201 atggtcgtct tccctgtttt cctactttta ttggtaacca atattaagag tcaacagagg
    37261 gggcgtagtg ctagaagaag ccgaagagaa acgccagtta gcctatggag tcgtttcttc
    37321 aaaggaaatc tatatctgct agtttttggg tttgtctatc ttttgtctgt tccttttttg
    37381 atgaagtttg tcctttatcc agtaccttat caagaacgta atcgtcttgc tgatttggta
    37441 aaagaggaga caaatacgga agatgctatc tatgcatggg atgatactgc gactctttat
    37501 cgtaagagtg agcgcttgtc gccatcggcg attttgtccc cgttgcacta tacagcaact
    37561 gaggaaaatc gtaataagtt acttaatgac ttgaaagaaa aacaacctaa ggtgattgtg
    37621 gtaaatgata aggtggtagt ctggtctgaa gtggaaacac tcttaaaaga aaattaccaa
    37681 caagtaaaga ctgattactc agagtttaaa gtctataaaa ttaaataacc aaatcaatat
    37741 cttgtgtatt tttaaaaatt ttaggatttt taacacaaga tattgatttt tctttttaga
    37801 gtggtataat actttttaga aagaacattt tagaaaagag catgcatatg attgcactag
    37861 aagaaaaaat tacaattttg ccaactctct tcgtcgagaa acgagatggg agacgtgttg
    37921 tatttgatgt ggacaagatt gacaaggctc tccacaaggc ggctgacaag gttatggatg
    37981 tgacacccct ggttgaaaaa cgcctcaatg atctgactga gcgaattatt acagaaattc
    38041 atagtcgctt tccacaggga attaagattt acgaaattca aaatatcgta gaacatgaac
    38101 tccttgaagc caaagaatat gcgctggctg aggagtatat tacttatcgg acacagaggg
    38161 attttgagcg ctcaaaagcg acggatatca actttagtat tcataaactt ctcaacaaag
    38221 accagacagt tgtcaatgaa aacgctaata aagacagtga tgtctttaac actcagcgtg
    38281 atttgacagc agggattgtt gggaaatcaa tcggactgca aatgcttcct aagcacgtag
    38341 ccaatgccca ccaaaagggg gatatccact atcacgattt ggactacagt ccctataccc
    38401 ctatgaccaa ctgctgtttg attgatttta agggtatgtt ggaaaatggt tttaagattg
    38461 gaaatgcaga ggtagagagt cccaagtcta tccagactgc gacagcacag atttctcaaa
    38521 tcattgccaa cgttgcttct agccagtacg gtggctgttc agctgaccgt atcgatgaaa
    38581 ttttggcgcc ttatgcagag aagaattatc aaaaacatct caaagatgca gaagagtggg
    38641 tattgcctga aaaacaggaa gattacgctt ggaagaaagc gcaaaaggac atctacgatg
    38701 ccatgcaatc tcttgagtat gaaatcaata ctctcttcac ttcaaatgga caaacacctt
    38761 ttacttcgtt aggttttggt ctgggaacca gtcgttttga acgagaaatt caaaaagcta
    38821 ttttaaacat tcgcatcaag ggtcttggtt cagaacaccg tacggctatc tttcctaaac
    38881 ttatctttac gcttaaaaga ggcctcaact tagaggaagg aactcccaac tatgacatca
    38941 agcagttggc tctagagtgt gcaaccaagc ggatgtatcc agacgtcttg tcttatgata
    39001 agattgttga tttgacaggt tctttcaagg tgcctatggg ctgccgttct ttccttcaag
    39061 ggtggaagga tgaaaatggt gtagaagtca attcaggtcg catgaatctg ggtgttgtga
    39121 cggttaatct gcctcgtatt gctcttgagt ctgaaggtga tatgaataag ttctgggaaa
    39181 tcttcaacga gcgaatgaat atcgcagaag atgctcttgt ttaccgtgtc gaacgcacta
    39241 aagaggcgac accagcgaat gctcctattc tttatcagta cggtgctttt ggccatcgtc
    39301 taggtaaaga agaaagtgtt gaccagctct ttaagaatcg tcgtgcgacc gtttcgctgg
    39361 gctatatcgg cttgtatgaa gtagcgacag ttttctttgg taacagctgg gaaagtaatc
    39421 cagatgctaa ggaattcacg ctagacatca ttcacgatat gaaacgccgt gtagaagagt
    39481 ggtcagacca atatggctac catttctcta tctactcaac accatccgaa agtctgacag
    39541 accgtttctg ccgactagat atagacaagt ttggctctat tcctgatatc acagacaagg
    39601 aatactacac caactctttc cactacgatg ttcgtaaaaa tccaacaccg tttgaaaaat
    39661 tggactttga gaaagtctat ccagaagcag gtgcgtcagg tggtttcatc cattattgtg
    39721 agtatccagt ccttcagcaa aatccaaagg ccttggaagc tgtctgggat tatgcttatg
    39781 accgtgtagg ctatctaggc accaatactc cgattgaccg ttgctacaag tgtgactttg
    39841 aaggggattt tgaaccaact gagagagggt ttgcttgtcc aaactgtggc aatagcgatc
    39901 ctaaaacagt agacgttgtt aaacggactt gtggctatct tggcaatcct caagcgagac
    39961 caatggttaa cgggcgtcac aaggaaatcg ctgcgcgtgt caaacatatg aatggttcaa
    40021 cgattaaaat agctgggcat caagtaacaa attagaaaga aatgaaatgg gaaaatatca
    40081 actagacgat aaggggcgcg cacaagtgac ccgttatcac gagaaacact ctaaaggtgg
    40141 agctggtaag aaagaacgct tgcttagctt cagagaacaa tttttaaaca agaacaagaa
    40201 aaaataaaag tgagagccag ctctcgcttt tctcatagtg ggaggtaggg atggaattac
    40261 gcagaccaag attagcagat aaagaaacag ttttagagat gatgacagag tttgaaaaat
    40321 ttcagtcgcc tcacgacggc ggtttctgga atacagagaa ctttgtgtat gaagactggt
    40381 tagaaagcaa tcaggaacag gaaatgggga ttaatctgcc tgaaggatgg gttcctgcaa
    40441 ttcagttagt ggttttttct gagaaaggtc aagcagttgg atttcttaat ctccggttgc
    40501 gcctcagtaa ctttctacta gaagaaggtg ggcacattgg ctactccatt cgtccatctg
    40561 aaagaggcaa gggttatgca aaagagactc tccgtcaggg cttgcaagtt gctaaggaaa
    40621 agaacatcaa gaaagctctg gtgacctgta gcgtgaataa tcctgctagc agagcagtca
    40681 ttctagcaaa tgatggaata tttgaggatg ctcgcaatgg agtcgagcgt tattggatag
    40741 aggtagcgaa tgaataatcc aaaaccacaa gaatggaaaa gcgaggaact tagtcaaggt
    40801 cgtatcattg actacaaggc ctttaacttt gtggacggag aaggcgtgcg caactctctc
    40861 tatgtagcag gttgcatgtt tcactgcgag gggtgttata atgtagcgac ctggtccttc
    40921 aatgcaggca ttccctatac agcagaatta gaagagcaga tcatggcaga tcttgctcag
    40981 ccctatgttc aaggtttgac tttgttggga ggggagcctt ttcttaatac tgggattctc
    41041 ttgccacttg ttaagcggat tcggaaggaa ttgccagaca aggacatctg gtcctggacg
    41101 ggctacactt gggaagaaat gatgttggaa actccagata aactggaact cttatcactg
    41161 attgacattc ttgtcgatgg aagatatgat cgaactaaga gaaatcttat gctccagttt
    41221 cgaggttcgt ctaaccaacg aattatcgat gtgcaaaaat cgctcaaaag tgggcaagta
    41281 gtgatttggg acaagctcaa tgacggaaaa gaaagctatg aacaggtgaa gagagaatga
    41341 agaaaaaaga cttagtagac caactagtct cagagatcga gacggggaaa gtcaggacac
    41401 tgggaatata cggtcatgga gcttcaggta aatcaacctt tgcacaggaa ttgtaccaag
    41461 ctttagattc tactacagta aatttgctag agacagatcc ctatatcacc tcaggacgcc
    41521 atctggtagt acccaaggac gcgccgaatc aaaaggtgac agccagtctg ccagtggcgc
    41581 atgaactgga gagtttgcag agagatatcc ttgccttgca ggcgggtatg gatgtcttga
    41641 caattgaaga accttggaag gctagtgagg tcttgtctgg agccaaacca attttgattg
    41701 tcgaagggat gtctgttggt tttctaccca aggaactctt tgaaaaaacc atctgtttct
    41761 acacggatga ggagaccgaa ttaaagcgac gccttgctag agatacgact gtgagaaatc
    41821 gcgatgcatc ctttatattg gctagccatc agatgagacg ggagcagtat ctgcgatact
    41881 ataaagaaac tgagtctaag gcggatatct tagtggacca atcagaagat aaatttgatg
    41941 tcaagaggac ttaacttatg tatagaagaa atatagaaga aaatccctaa ttttagaaag
    42001 aaaaagtagg aaaacagttt catcccaaaa aaacgaaaaa acctaacaaa tcccttgcaa
    42061 tcgcagggga tttgtgttat tctattatgg tgctgtaaat tacagcctta gttttgatgc
    42121 aagaggttgc gacacgctcg gttgcattgc cacgcaacac cgcgtcggtt ttcttgtgga
    42181 gctagcctat tatcttaaat agacgaaaag gagaaaaaga tggcaaacaa aaaaatccgt
    42241 atccgtttga aagcttacga acaccgtacg cttgacacag cggctgcaaa aatcgtagaa
    42301 tcagctactc gtacaggtgc acaagttgcg ggtccaatcc cacttccaac tgaacgtagc
    42361 ctctacacaa tcattcgtgc gactcacaaa tacaaagact ctcgcgaaca atttgaaatg
    42421 cgtacacaca aacgtttgat cgatatcgtt aacccaactc aaaaaacagt tgatgccttg
    42481 atgaaattgg atcttccaag tggtgtaaac gtagaaatca aactttaatc taaaatataa
    42541 aagagcagag gctggtgttt caatctaatt gaacacgggc taaactcggt gtgaaaaaga
    42601 taaacttcct cgcgtctgct agacactgtg tcagtttcct attttcacgt tgagtttgac
    42661 gccctttgta tcttagactt gagcataaaa aacgctcgtt aaaaactttt tgaataaaaa
    42721 tatagaaaag gaactatttt ctcatgacaa aaggaatctt agggaaaaaa gtgggaatga
    42781 ctcaaatctt cactgaagct ggcgaattga tccctgtaac agttattgaa gcaactccaa
    42841 acgttgttct tcaagttaaa actgttgaaa cagacggata caacgctatc caagttggtt
    42901 tcgatgacaa acgcgaagta ttgagcaaca aacctgctaa aggacatgta gcgaaagcta
    42961 acacggctcc taagcgcttc attcgtgaat tcaaaaacgt tgaaggcttg gaagttggtg
    43021 ctgaaattac agttgaaaca ttcgcagctg gagacgttgt tgacgtaact ggtacttcta
    43081 aaggtaaagg tttccaaggt gttatcaaac gccacggaca atcacgtgga ccaatggctc
    43141 acggttctcg ttaccaccgt cgtccaggtt ctatgggacc tgttgcacct aaccgcgtat
    43201 tcaaaggtaa aaaccttgca ggacgtatgg gtggtgaccg cgtaacaatt caaaatcttg
    43261 aagttgtaca agttgttcca gaaaagaacg ttatccttat caaaggtaac gtaccaggtg
    43321 ctaagaaatc tcttatcact atcaaatcag cagttaaagc tggtaaataa taaagaaagg
    43381 ggaaatcagt cacaatggca aacgtaacat tatttgacca aactggtaaa gaagctggcc
    43441 aagttgttct tagcgatgca gtatttggta tcgaaccaaa tgaatcagtt gtgtttgatg
    43501 taatcatcag ccaacgcgca agccttcgtc aaggaacaca cgctgttaaa aaccgctctg
    43561 cagtatcagg tggtggacgc aaaccatggc gtcaaaaagg aactggacgt gctcgtcaag
    43621 gttctatccg ctcaccacaa tggcgtggtg gtggtgttgt cttcggacca actccacgtt
    43681 catacggcta caaacttcca caaaaagttc gtcgcctagc tcttaaatca gtttactctg
    43741 aaaaagttgc tgaaaacaaa ttcgtagctg tagacgctct ttcatttaca gctccaaaaa
    43801 ctgctgaatt tgcaaaagtt cttgcagcat tgagcatcga ttctaaagtt cttgttatcc
    43861 ttgaagaagg aaatgaattc gcagctcttt cagctcgtaa ccttccaaac gtgaaagttg
    43921 caactgctac aactgcaagt gttcttgaca tcgcaaatag cgacaaactt cttgtcacac
    43981 aagcagctat ctctaaaatc gaggaggttc ttgcataatg aatttgtatg atgttatcaa
    44041 aaaacctgtc atcactgaaa gctcaatggc tcaacttgaa gcagggaaat atgtatttga
    44101 agttgacact cgtgcacaca aacttttgat caagcaagct gttgaagctg ctttcgaagg
    44161 tgttaaagtt gccaatgtta acacaatcaa cgtaaaacca aaagctaaac gtgttggacg
    44221 ttacactggt tttactaaca aaactaaaaa agctatcatc acacttacag ctgattctaa
    44281 agcaatcgag ttgtttgctg ctgaagctga ataatctaag gaggaaatat cgtgggaatt
    44341 cgtgtttata aaccaacaac aaacggtcgc cgtaatatga cttctttgga tttcgctgaa
    44401 atcacaacaa gcactcctga aaaatcattg cttgttgcat tgaagagcaa ggctggtcgt
    44461 aacaacaacg gtcgtatcac agttcgtcac caaggtggtg gacacaaacg tttctaccgt
    44521 ttggttgact tcaaacgtaa taaagacaac gttgaagcag ttgttaaaac aatcgagtac
    44581 gatccaaacc gttctgcaaa catcgctctt gtacactaca ctgacggtgt gaaagcatac
    44641 atcatcgctc caaaaggtct tgaagtaggt caacgtatcg tttcaggtcc agaagcagat
    44701 atcaaagtcg gaaacgctct tccacttgct aacatcccag ttggtacttt gattcacaac
    44761 atcgagttga aaccaggtcg tggtggtgaa ttggtacgtg ctgctggtgc atctgctcaa
    44821 gtattgggtt ctgaaggtaa atacgttctt gttcgtcttc aatcaggtga agttcgtatg
    44881 attcttggaa cttgccgtgc tacagttggt gttgtcggaa acgaacaaca tggacttgta
    44941 aaccttggta aagcaggacg tagccgttgg aaaggtatcc gcccaacagt tcgtggttct
    45001 gtaatgaacc ctaacgatca cccacacggt ggtggtgaag gtaaggcacc agttggtcgt
    45061 aaagcaccat ctactccatg gggcaaacct gctcttggtc ttaaaactcg taacaagaaa
    45121 gcgaaatctg acaaacttat cgttcgtcgt cgcaacgaga aataatatta aactagtcgc
    45181 ttaagcaact agtaaatccg ccagctcggt agcgctccat aggagtgcaa gccgctgtgg
    45241 tacaacattt aaaggagaaa atataaaaat gggacgcagt cttaaaaaag gacctttcgt
    45301 cgatgagcat ttgatgaaaa aagttgaagc tcaagctaac gacgaaaaga aaaaagttat
    45361 taaaacttgg tcacgtcgat caacgatctt cccaagtttc attggttaca ctattgcagt
    45421 ttatgacgga cgtaaacacg tacctgttta catccaagaa gacatggtag gccacaaact
    45481 tggtgaattt gcaccaactc gtacttacaa aggtcacgct gcagacgaca agaaaacacg
    45541 tagaaaataa ggagaacata aatggcagaa attacttcag ctaaagcaat ggctcgtaca
    45601 gtacgtgttt cacctcgtaa atcacgtctt gttcttgata acatccgtgg taaaagcgta
    45661 gccgatgcaa tcgcaatctt gacattcact ccaaacaaag ctgctgaaat catcttgaaa
    45721 gttttgaact cagctgtagc taacgctgaa aacaactttg gtttggataa agctaacttg
    45781 gtagtatctg aagcattcgc aaacgaagga ccaactatga aacgtttccg tccacgtgcg
    45841 aaaggttcag cttcaccaat caacaaacgt acagctcaca tcactgtagc tgttgcagaa
    45901 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggcatc
    45961 atccgtgatt gggatgccaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
    46021 gatcttgcaa tccgtaaatt cgttcaaaaa gaacttgctg acgcagcagt ttcaactatt
    46081 gaaatcgaac gcgcagtaaa caaagttaac gtttcacttc acactgctaa accaggtatg
    46141 gttatcggta aaggtggtgc taacgttgat gcactccgtg caaaacttaa caaattgact
    46201 ggaaaacaag tacacatcaa catcatcgaa atcaaacaac ctgatttgga tgctcacctt
    46261 gtaggtgaag gaattgctcg tcaattggag caacgtgttg ctttccgtcg tgcacaaaaa
    46321 caagcaatcc aacgtgcaat gcgtgctgga gctaaaggaa tcaaaactca agtatcaggt
    46381 cgtttgaacg gtgcagatat cgcccgtgct gaaggatact ctgaaggaac tgttccgctt
    46441 cacacacttc gtgcagatat cgattacgct tgggaagaag cagatactac atacggtaaa
    46501 cttggtgtta aagtatggat ctaccgtggt gaagttcttc cagctcgtaa aaacactaaa
    46561 ggaggtaaat aaccaatgtt agtacctaaa cgtgttaaac accgtcgtga attccgtgga
    46621 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtagcat tcggtgaata cggtcttcaa
    46681 gctacaacta gccactggat cactaaccgc caaatcgaag ctgctcgtat cgccatgact
    46741 cgttacatga aacgtggtgg taaagtttgg attaaaatct tcccacacaa atcatacact
    46801 gctaaagcta tcggtgtgcg tatgggatct ggtaaagggg cacctgaagg ttgggtagca
    46861 ccagttaaac gtggtaaagt gatgttcgaa atcgctggtg tatctgaaga gattgcacgt
    46921 gaagcgcttc gacttgctag ccacaaattg ccagttaaat gtaaattcgt aaaacgtgaa
    46981 gcagaataag gagaaggcat gaaacttaat gaagtaaaag aatttgttaa agaacttcgt
    47041 ggtctttctc aagaagaact cgcgaagcgc gaaaacgaat tgaaaaaaga attgtttgaa
    47101 cttcgtttcc aagctgctac tggtcaattg gaacaaacag ctcgcttgaa agaagttaaa
    47161 aaacaaatcg ctcgtatcaa aacagttcaa tctgaagcga aataatagac tagggaagga
    47221 gaaatttcaa tggaacgcaa taatcgtaaa gttcttgttg gacgtgttgt atctgacaaa
    47281 atggacaaga caatcacagt tgtagttgaa acaaaacgta accacccagt ctatggtaaa
    47341 cgtattaact actctaaaaa atacaaagct catgatgaaa acaatgttgc caaagaaggc
    47401 gatatcgtac gtatcatgga aactcgcccg ctttcagcta caaaacgttt ccgtcttgta
    47461 gaagttgttg aagaagcggt catcatctaa tcaaacctga aaggagaaaa ctgaaatgat
    47521 tcaaacagaa actcgtttga aagtcgcaga caacagcggt gctcgcgaaa tcttgactat
    47581 caaagttctt ggtggttcag gacgtaaatt tgcaaacatc ggtgatgtta tcgtggcatc
    47641 tgtaaaacaa gctactcctg gtggtgcggt taaaaaaggt gacgttgtta aagcagttat
    47701 cgttcgtact aaatcaggtg ctcgtcgtgc tgatggttca tacatcaaat ttgacgaaaa
    47761 cgcagcagtt atcatccgtg aagacaaaac tcctcgcgga acacgtatct ttggcccagt
    47821 tgcacgtgaa ttgcgtgaag gtggcttcat gaagatcgtg tcacttgctc cagaagtact
    47881 ttaattttta ggaacaaact agtcccctag cttcaagcta gggtgccctt atgggcgtaa
    47941 gaaaaatcaa ggagaaacct aatgtttgta aaaaaaggcg acaaagttcg cgtaatcgct
    48001 ggtaaagata agggaacaga agctgttgtc cttactgccc ttccaaaagt aaacaaagtt
    48061 atcgttgaag gtgttaacat tgttaagaaa caccaacgtc caactaacga gcttcctcaa
    48121 ggtggtatca tcgagaaaga agcagctatc cacgtatcaa acgttcaagt tttggacaaa
    48181 aatggtgtag ctggtcgtgt tggatacaaa tttgtagacg gtaaaaaagt tcgctacaac
    48241 aaaaaatcag gcgaagtgct tgattaatca cgaaggaaag gagaagtata atggcaaatc
    48301 gtttaaaaga aaaatatctt aatgaagtag ttcctgcttt gacagaacaa ttcaactact
    48361 catcagtgat ggctgtgcct aaagtagata agattgtttt gaacatgggt gttggtgaag
    48421 ctgtatcaaa cgctaaaagc cttgaaaaag ctgctgaaga attggcactt atctcaggtc
    48481 aaaaaccact tatcactaaa gctaaaaaat caatcgccgg cttccgtctt cgtgaaggtg
    48541 ttgcgatcgg tgcaaaagtt acccttcgtg gtgaacgtat gtacgaattc ttggataaat
    48601 tggtatcagt ttcacttccg cgtgtacgtg acttccacgg tgttccaaca aaatcatttg
    48661 atggacgcgg gaactacaca cttggtgtga aagaacaatt aatcttccca gaaatcaact
    48721 tcgatgacgt tgacaaaact cgtggtcttg acatcgttat cgtaacaact gctaacactg
    48781 acgaagagtc acgtgcattg cttacaggcc ttggaatgcc ttttgcaaaa taatatagga
    48841 ggtaaatcta atggctaaaa aatcaatggt agctagagag gctaaacgcc aaaaaattgt
    48901 tgaccgttat gctgaaaaac gtgctgcatt aaaggcggca ggggactacg aaggtttatc
    48961 taaattacct cgcaacgcct caccgactcg tttacataat cgttgtagag ttacggggcg
    49021 cccacattca gtttaccgca aatttggtct gagtcgtatc gcttttcgcg aacttgcgca
    49081 taaaggtcaa attcctggtg taacaaaagc atcttggtaa tttaagatat caagagtgtc
    49141 aaaactccaa gtaaaaatag gaaacttgac gaagaaacta aagtttctag gaaagtttat
    49201 ctttttcaca cagagtttag cccgggttca attgggcttg ccaatttgaa cacgagctac
    49261 agctttggca aaaaagacca atttgctttg gagcattgct tctgcattaa attgtctatt
    49321 tttgctcgtg ctgttacgct ctttgtatca tgtattaact agcaagtgca acttgcaaac
    49381 tactagtaag aggagaaaaa caaaatggtt atgactgacc caatcgcaga cttcctaact
    49441 cgtattcgta atgctaacca agctaaacac gaagtacttg aagtacctgc atcaaacatc
    49501 aaaaaaggga ttgctgaaat ccttaaacgc gaaggttttg taaaaaacgt tgaaatcatt
    49561 gaagatgaca aacaaggcgt catccgtgta tttcttaaat acggaccaaa tggtgagaaa
    49621 gttatcacta acttgaaacg tgtttctaaa ccaggacttc gtgtctacaa aaaacgtgaa
    49681 gaccttccaa aagttcttaa cggacttgga attgccatcc tttcaacttc tgaaggtttg
    49741 cttactgata aagaagcacg ccaaaagaat gttggtggtg aggttatcgc ttacgtttgg
    49801 taaaatcaag atacaaagct cgtaaagaac aaagcaaaat taggaagttg gagaagtttg
    49861 tttacaaaca agccaactta tctattttgc acagttctta gagcgtgttc agttcagctc
    49921 ttgaactaaa taagtatctg aaccccgtga aaactggccg ttctggcctg acaatttaac
    49981 aggagaaaat aaacatgtca cgtattggta ataaagttat cgtgttgcct gctggtgttg
    50041 aactcgctaa caatgacaac gttgtaactg taaaaggacc taaaggagaa cttactcgtg
    50101 agttctcaaa agatattgaa atccgtgtgg aaggtactga aataactctt caccgtccaa
    50161 acgattcaaa agaaatgaaa actatccacg gaactactcg tgcccttttg aacaacatgg
    50221 ttgttggtgt atcagaagga ttcaagaaag aacttgaaat gcgtggggtt ggttaccgtg
    50281 cacagcttca aggatctaaa cttgttttgg ctgttggtaa atctcatcca gacgaagttg
    50341 aagctccaga aggaattact tttgaacttc caaacccaac aacaatcgtt gttagcggaa
    50401 tttcaaaaga agtagttggt caaacagctg cttacgtacg tagccttcgt tcaccagaac
    50461 catataaagg taaaggtatc cgttacgttg gtgaattcgt tcgccgtaaa gaaggtaaaa
    50521 caggtaaata atgttgagtg gttgatcatc aaccaccaac ctattttcca actttgtgca
    50581 tagcacacga tttaaaacta aagaggtgaa aactgtgatt tcaaaaccag ataaaaacaa
    50641 actccgccaa aaacgccacc gtcgcgttcg cggaaaactc tctggaactg ctgatcgccc
    50701 acgtttgaac gtattccgtt ctaatacagg catctacgct caagtgattg atgacgtagc
    50761 gggtgtaacg ctcgcaagtg cttcaactct tgataaagaa gtttcaaaag gaactaaaac
    50821 tgaacaagcc gttgctgtcg gtaaactcgt tgcagaacgt gcaaacgcta aaggtatttc
    50881 agaagtggtg ttcgaccgcg gtggatatct atatcacgga cgtgtgaaag ctttggctga
    50941 tgcagctcgt gaaaacggat tgaaattcta ataggaggac actagaaaat ggcatttaaa
    51001 gacaatgcag ttgaattaga agaacgcgta gttgctgtca accgtgttac aaaagttgtt
    51061 aaaggtggac gtcgtcttcg tttcgcagct cttgttgttg ttggtgacca caatggtcgc
    51121 gtaggatttg gtactggtaa agctcaagaa gttccagaag caatccgtaa agcagtagat
    51181 gatgctaaga aaaacttgat cgaagttcct atggttggaa caacaatccc acacgaagtt
    51241 ctttcagaat tcggtggagc taaagtattg ttgaaacctg ctgtagaagg ttctggagtt
    51301 gccgctggtg gtgcagttcg tgccgttgtg gaattggcag gtgtggcaga tattacatct
    51361 aaatcacttg gttctaacac tccaatcaac attgttcgtg caactgttga aggtttgaaa
    51421 caattgaaac gcgctgaaga aattgctgcc cttcgtggta tttcagtttc tgatttggca
    51481 taagaaaggg gataaaatgg ctcaaattaa aattactttg actaagtctc caatcggacg
    51541 cattccatca caacgtaaaa ctgttgtagc acttggactt ggcaaattga acagctctgt
    51601 tattaaagaa gataacgctg ctatccgtgg tatgatcaca gcagtatctc acttagtaac
    51661 agttgaagaa gtaaactaat gaagttttag gggatgtgca ctgtaccatc ccctaaaact
    51721 agatatagtc atctatgatg acatcgtata ggcgagttga tgggggagac aaccttttct
    51781 cccttatcgg cgctagcatt ttacaaaaga ggagaaaata aaaatgaaac ttcatgaatt
    51841 gaaacctgca gaaggttctc gtaaagtacg taaccgcgtt ggtcgtggta cttcatcagg
    51901 taacggtaaa acatctggtc gtggtcaaaa aggtcaaaaa gctcgtagcg gtggcggagt
    51961 tcgccttggt tttgaaggtg gacaaactcc attgttccgt cgtcttccaa aacgtggatt
    52021 cactaacatc aacgctaaag aatacgcaat tgtgaacctt gaccaattga acgtctttga
    52081 agatggtgct gaagtaactc cagttgttct tatcgaagca ggaattgtta aagctgaaaa
    52141 gtcaggtatt aaaattcttg gtaacggtga gttgactaag aaattgactg tgaaagcagc
    52201 taaattctct aaatcagctg aagaagctat cactgctaaa ggtggttcag tagaagtcat
    52261 ctaagagagg tgacctatgt tttttaaatt attaagagaa gctcttaaag tcaagcaggt
    52321 tcgatcaaaa attttattta caatttttat cgttttggtc tttcgtatcg gaactagcat
    52381 tacagttcct ggtgtgaatg ccaatagctt gaatgcttta agtggattat ccttcttaaa
    52441 catgttgagc ttggtgtcgg ggaatgccct aaaaaacttt tcgatttttg ccctaggagt
    52501 tagtccctat atcaccgctt ctattgttgt ccaactcttg caaatggata ttttacccaa
    52561 gtttgtagag tggggtaaac aaggggaagt aggtcgaaga aaattgaatc aagctactcg
    52621 ttatattgct ctagttctcg cttttgtgca atctatcggg attacagctg gttttaatac
    52681 cttggctgga gctcaattga ttaaaactgc tttaactcca caagtttttc tgacgattgg
    52741 tatcatctta acagctggta gtatgattgt cacttggttg ggtgagcaaa ttacagataa
    52801 gggatacgga aacggtgttt ccatgattat ctttgccggg attgtttcct caattccaga
    52861 gatgattcag ggcatctatg tggactactt tgtgaacgtc ccaagtagcc gtatcacttc
    52921 atctatcatt ttcgtaatca ttttgattat tactgtattg ttgattattt actttacaac
    52981 ttatgttcaa caagcagaat acaaaattcc aatccaatat actaaggttg cacaaggtgc
    53041 tccatctagc tcttaccttc cgttaaaggt aaaccctgct ggagttatcc ctgttatctt
    53101 tgccagttcg attactgcag cgcctgcggc tattcttcag tttttgagtg ccacaggtca
    53161 tgattgggct tgggtaaggg tagcacaaga gatgttggca actacttctc caactggtat
    53221 tgccatgtat gctttgttga ttattctctt tacattcttc tatacgtttg tacagattaa
    53281 tcctgaaaaa gcagcagaga gcctacaaaa gagtggtgcc tatatccatg gagttcgtcc
    53341 tggtaaaggt acagaagaat atatgtctaa acttcttcgt cgtcttgcaa ctgttggttc
    53401 cctcttcctt ggtgtgattt ccattttacc gattgcagct aaagatgtat ttggtctttc
    53461 tgatgttgtt gcctttggtg gaacaagtct cttgatcatt atctctacag gtatcgaagg
    53521 aatcaagcaa ttggaaggtt acctattgaa acgtaagtat gttggtttca tggacagaac
    53581 agaataaaag tatttactga atcagtaaat gctgagggag tggaggttta aactctgaca
    53641 tttgtaagag ttggatctcc cctcttctat tttgttttta aataggggtg aaaagacttt
    53701 ttgcttctat ttaaaaataa aataaggaga tcaaatcatg aatcttttga ttatgggctt
    53761 acctggtgca ggtaagggaa ctcaagcagc aaaaatcgta gaacaattcc atgttgcaca
    53821 tatctcaaca ggtgatatgt tccgcgctgc aatggcaaat caaactgaaa tgggtgttct
    53881 tgctaagtca tatattgaca agggtgaatt ggttcctgac gaagttacaa atggaatcgt
    53941 aaaagaacgc ctttcacaag atgatattaa agaaacagga ttcttattgg atggttaccc
    54001 acgtacaatt gaacaagctc atgccttgga caaaacattg gctgaacttg gcattgaact
    54061 agaaggtgtt atcaatattg aagtgaaccc tgacagcctc ttggaacgtt tgagtggccg
    54121 tatcatccac cgcgtaactg gagaaacttt ccacaaggtc tttaacccac cagttgacta
    54181 taaagaagaa gattactacc aacgtgaaga tgataagcct gagacagtaa aacgtcgttt
    54241 ggatgttaat attgctcaag gagaaccaat cattgctcac taccgtgcca aaggtttggt
    54301 tcatgacatc gaaggtaatc aagatatcaa tgatgtcttt tcagatattg aaaaagtatt
    54361 gacaaatttg aaataaagcg tttttcatac ttgcaaaaat tcgctacaaa tgttatactg
    54421 agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg aaatttatgg
    54481 aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt agttgataca
    54541 atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt agcaacagtt
    54601 tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt tactgtcgaa
    54661 atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata atcgaaaaac
    54721 ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga atactgtaaa
    54781 gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa acacaaacaa
    54841 cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt gatattccaa
    54901 atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt gcaacatcta
    54961 agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat cttacatcag
    55021 atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt gaccttcgtc
    55081 gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt ggtatccgtc
    55141 accgtcgtgg acttcctgtc cgtggacaaa acactaaaaa caacgctcgc actcgtaaag
    55201 gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag tcttggctaa
    55261 accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc atattcacgc
    55321 tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa ttgcttggtc
    55381 atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg ctgctcaaat
    55441 ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag ttgaagttac
    55501 tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg ccgctggtct
    55561 tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc gtcctccaaa
    55621 acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga gtaactaaat
    55681 gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt atggcaagtt
    55741 tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc ttcgtcgtgt
    55801 acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg gtgtgttaca
    55861 tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc tgaacattaa
    55921 aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg atgttgaagg
    55981 tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa ttgtaaatcc
    56041 agatcattat ctctttacaa tcggtgaagg ttcttctcta aaagcgacta tgactgttaa
    56101 cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac cagttggaac
    56161 acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag tggaacctgc
    56221 tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga caaatggaac
    56281 aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac atcttgattt
    56341 gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag ctgatactga
    56401 atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg tgcgttcata
    56461 caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa aatctgaagc
    56521 agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga aactcaaact
    56581 cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc ttaccgtaaa
    56641 ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac tgaccttttg
    56701 atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa aactgttgaa
    56761 aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc agctgctttc
    56821 gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta cacttctact
    56881 acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg taacggtgga
    56941 tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat ggcgatcatc
    57001 gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct tgtgctctta
    57061 gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat cataagttgg
    57121 gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg taagcaggcg
    57181 tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct gtttaatgtt
    57241 aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat aactgttgtt
    57301 ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga attaggattg
    57361 aatattgacg atatctctca aactgtattg gatgaatatt ttacgatgat ggctgttgta
    57421 tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc ttttgggcaa
    57481 actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat gtataatatc
    57541 taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat tgaggagcaa
    57601 aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat cgatccagat
    57661 atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc taatttagta
    57721 gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa gcgtgtatcg
    57781 gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt ggttctggca
    57841 aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg tttttctgcc
    57901 ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat tcctcgcgct
    57961 ttggctgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa gtctggtatt
    58021 aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacagcaaa tctttcagat
    58081 atgggagtgg ccaagttggt tgtattcgct aatgctgttg aggacaatcc atttatggcg
    58141 ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt ttctggtcct
    58201 ggtgttgtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt agtagccgaa
    58261 acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg tcaaatggcc
    58321 agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc aacccctgcg
    58381 gttggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt tggcacgcat
    58441 ggaacgacag ctgccttggc cctcttgaac gaccaagtta aaaagggtgg agtgatggcc
    58501 tgtaaccagg tcggtggtct atctggtgcc tttatccctg tttctgagga tgaaggaatg
    58561 attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat gacggctatc
    58621 tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga aactattgcg
    58681 gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac agctgttcgt
    58741 atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt aggaactgca
    58801 cccgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg tggacaaatc
    58861 ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa gttctattta
    58921 agattagacg tgtatactat aatcattaaa taaagacctc ctaatattat ttgaaacaga
    58981 taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat gaactcctaa
    59041 actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta ttttatcatt
    59101 catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt gtatttggta
    59161 cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag cgatactccc
    59221 ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg agaatctgat
    59281 ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac catgggaatt
    59341 atacttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa gcgtatcaga
    59401 gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat gggcattatt
    59461 cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact ggctgagggc
    59521 ttggtagagg tcgatacagc tggttgggct gaaggttggg aaaaactcag tggccgaatc
    59581 aaggaaggct ttgaaataat tgcaaaagaa atggaagatc aaggtggagg taacgcactt
    59641 gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg catgcatccg
    59701 catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca gtttagggtt
    59761 gaagttgtcg gtgaccgtag ttaccgagag ctaggacgtg agaagatgga agaaggctct
    59821 atttaatcag tctagacttg cttgccatga gctagggatt tgataaggat atcaagataa
    59881 gaaaaaacag ccgagggtac tcctttcggc tgtttttgat gtggaaaact aaagtgtaat
    59941 gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta gaacagtcag
    60001 gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg tataaatagc
    60061 tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga gttttgaaat
    60121 cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca ttggagttgt
    60181 aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt cttcaatact
    60241 tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta atcttctgac
    60301 agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc cacttccaaa
    60361 tagaccagag aaatgaaggc aatccctaga acggttcctg gtacaatata aggtaccata
    60421 ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc taacggctag gtaggagata
    60481 aatgtcgcaa atagaacaac tagaactaag gcaatcaaag ggatacgaat ggtattgaaa
    60541 atagcagatc ccatacgatt gaaagctacc ttgtaactgt ttggagaata acctttaaca
    60601 aataccatac ctgatgtttt taggaaagag gtataaatta agtagatttg aggtaaaaca
    60661 gagataaaga taattccgta gactgttgca taaatggcag ccatttttcc ttttgtagtt
    60721 tttttaggct caattggatg gagcagattc atgctgaaac tgtagcggtt tgcaatgtgt
    60781 ttttggataa ggaaaattgc caaggcaatg ataatcgcca taattgcaaa agcagaattt
    60841 cctccaacct cgctaataaa ttgggtataa atcaggacag ggaaagtccg atatccttcg
    60901 ccaatcaaca taggcgttcc aaagtctgag aatgctctca taaatacaag caaggagctg
    60961 ctagtaaggt tggaactagg agaggtaaaa caaccgttac gataggttta aatccgaagg
    61021 accccatgct ttcagctgct tcaagtagag aattgtcaat actgttcatt gttccagcaa
    61081 catatagaaa taccagtggg aatagttgca gtgtaaagac aagtacaatt cctttgaatc
    61141 cataaatatc gatagctgga agatgaaggg catttgtcaa aaatttagtg atgaccccat
    61201 ttcgtcctag caagagaacc caggagtagg ctcctacgaa aggagctgac atggaagcaa
    61261 tgataatcaa tatttgtaga aatttcttct ccttgaagtc atacatagag aagagataag
    61321 ctaatagggt tcctacaact aaggaagtga cagtagcggt aatggaaacc ttgaaactgt
    61381 tgactagtgt ctcagagtag tagactttac taaagaaagt gacaaaatta gctagtgaga
    61441 attgtccttc atgtataagt gcttgcttga gcacggtaac gataggataa acgagaaaga
    61501 caagataggt aagaaagatg aagaaagagg aggttgtcca aatatttagt tttttacatt
    61561 ccatggttga ctccttttat caggttttgg gaaccatctg cagaaaagat gtttaatttt
    61621 tgcgtattga ttcgtagacg aatacgattg cctttttgta gttcttcttc aaaagttgat
    61681 tcttcactaa cttgaatttt tgaggcaaaa cctgtctcaa tgaaatactc cgtatttagt
    61741 ccaagataga cgctatcgct aatagttcct tcaatatctc cagattcatc tttgataaac
    61801 tcttcgggac gaatgcttac atgaatagct tgctcctcaa cctgatcaag agctggcatt
    61861 cgaagggcat agccatctga aaagacgata taagcgccgt cgctccgttt ttcaagatta
    61921 gtagggataa tatttgtgcg tccgataaag gttgccacaa actcattagc tggtttatga
    61981 tagagttctt ttggtcggcc gatttgttgg atcaccccat ctttcataac agcaatttgg
    62041 tctgaaatag ccatggcttc ttcttggtcg tgggttacat aaacagttgt aattcccact
    62101 tcgtgttgga ttgctcggat ggcttgacgc atatccaagc gaagtttggc ctccagatta
    62161 ctaagtggct cgtccatgag gagaacactt ggattaaccg ctaaggcgca tgccaaggtg
    62221 acacgttgtt gttgtccacc actgagttta tcgggctttc aatccgcata ttgagcaatt
    62281 tgcatgagtt caagatactt gttggtctgt tgaatcaatt cttcttttgg aaccttcttt
    62341 tgcataagac caaaagcaac gttgtctcgg acagtcaaat gtgggaaaat agcgtagttt
    62401 tggaaaacca gcccgatatt gcgtttgctg ggttccatat tattgatttt tgtatcatcg
    62461 aagtaaaatt ctccatcttt gatactgttg aaacctgcaa tcatacgaag aagggtcgtt
    62521 ttcccacatc ctgaagctcc aagaagggta aagagacttc cttttggaat tgtaatgttc
    62581 aaattctcaa taacagggac atcgtggtag atttttttgg cgttaataat ttcgatctca
    62641 ctcatagtga acctctttta ctgtttagat tggatatctg taaagacttc gttgtatttc
    62701 ttaacgatat ctgatttatt cttgatgaca taatcataat cttcagtgag tgttttgatt
    62761 ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt tacgaacagg acggttagta
    62821 gtggttgtac caagtgtatc ttgtacttct tgagagataa taaaatcgat aaatttcttg
    62881 gcattttcca tatttttagc ttttttaacg atagcagcac tagcaggtag gaagacggtt
    62941 ccttcttttg gatagactac tttaatgtta gctccgtcat ttaagagttt aactgctgga
    63001 tcctcataag agagaccaac agccatttct ccatcaacga ctgctttata gacaccagat
    63061 gaacttgaac cgattttata gtgtattgaa actagaatag tacacctcta cttctaaaac
    63121 attgttagaa atcgatttga ctgtcctgat taatttgtcc tgttcttatt tcattttact
    63181 ataccatcaa taagtgtgaa aagatctttt acataagacc aagccttatc atctttgtaa
    63241 ccaccttgag cttgtagcat atttgttaat tgagcaaagg cgctagaaga gtttgctggg
    63301 tcagcagttg cgatttttcc ttttagttca ggtttgagaa ggtcgctata tccttcgatg
    63361 ttcatgcctt tagttaaatc agggtggacg attaaaacac taccatctag tgtataagga
    63421 gtagagaagc cagttgtgtt ttgatattct ttgataacat tatcattttc ttttgaaata
    63481 tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc aaagataaca
    63541 tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc agtaccagct
    63601 tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt tgctccaatt
    63661 aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt atcagatgaa
    63721 ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt ctttttcatg
    63781 atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg tttttaaaac
    63841 ctacaattct attctatagt gtattgaatc tataacagta cactttgact gctaaaatat
    63901 ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc aattcactat
    63961 attagagtaa aattctctac aaaaagaaga atagcctatt tgactattct tccgagtgat
    64021 ttcaatttct ttggggaaat atggagatac tttttaaata ctttggcaaa atatttatag
    64081 tctgaaaatc caacttggtc agagatagcg cttaaagggg agttgggaga ttcagccatc
    64141 ttatctatag cttgtttcag gcgatattgt aagatatatt catttagagt catggggaag
    64201 tcttctttga taaccttata tagatgcttg ttatctgcaa atagctagag catttcaagg
    64261 aaataaacta gaaataacaa ttaatatggt ggttcagaaa taccttttga taatcaataa
    64321 gatcttcagg atgaagtgcg ttgattccat ccatttcata tttccgattt aataaacgat
    64381 atttgttttc accaaattga tgaaaaggga gtagttgaac ttggtcgata tttaatgagt
    64441 taaatagagt agcgaatttt tctgcatcct ctaaactatt gttaaaatta ggaataactg
    64501 ggattcttaa aacgatagtt ttattttgag aaaaagcata atgaatgttt ttaataatca
    64561 tttgattaaa aaccccagtc acttttttat gttttataga attataatgt tttaggtctg
    64621 tgtagataaa atccacatat tgaattaaat caataaattt ttcatgatca acaaaggcag
    64681 tagtttcaat ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg gctttagcaa
    64741 attcaaactg agcaaatatt tcacctcctg ataaagttaa acctccaccg gattcttcgt
    64801 aaaattcttt gtcttttaat acctctgtaa taatttcttc tacagtcttt tcttcaccga
    64861 ctaaggtgaa tttctctcgt tgagcatctt tcattttttc aggtttcatt ctttgagatt
    64921 caggattaga acaccatgga cagcgcagag gacatccttt taaaaaaaca gttgtacgaa
    64981 tacccgggcc gtcatgaatt gaaaagtgtt gaatattaaa aataattcct ttagatattt
    65041 ccataagagt tcctcctctt cataagtcta tcctatcaca aaaacgaaag aaaaacaatt
    65101 acgaacgaaa gtttaatttg ttgttttttg ctttttattt tggtagaata aaacggaggt
    65161 gtaaaatgaa aagattggaa caaattatta aattagtatc agaatatgaa aagatcgacg
    65221 ttaatacatt atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa gatttagata
    65281 aattagagtc aaaaggttta ttacacagag agcatggata tgctgtatta aatagtggag
    65341 atgacttaaa tgtacgtttg tcaattaact atgaaattaa gagaaaaatt gttcaggaag
    65401 cagtaaaatt ggtgtcagat aatgaaacaa taatgataga atctggatcg acctgtgctt
    65461 tacttgctga ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca aattcatttt
    65521 ttatagcaaa ttttgtgaga gcttatgatt catgtcgtat tattgttctt ggtggagagt
    65581 ttcagaagga ttcacaggtt actgtgggac ctttattaaa agaaatgata cagacttttc
    65641 atgtgcatca agcttttgtt gggacagatg gttacgataa agagatgggc tttacaggaa
    65701 aagatttaat gcgcagtgag gtagttcaat atatttcagc agcgtcggat aaagtcattg
    65761 tactaactga ctcaagtaaa tttgataaaa ggggtacagt aagaagattt gctttaagtc
    65821 aagtctatga agtaataaca gacgaaaaac tttctaaaca aaatatagct acattagaaa
    65881 atgctgggat aatggttaag gtagtttcgt aagaggttaa atgtatgaat caagatagga
    65941 ataaactgct ctctaaaatt gcttatctgt attatattga aaacttaaat cagtcacaaa
    66001 tagcagcaaa attaggaatt tatagaacct ctattagtag aatgttaaca gaagcaagga
    66061 atgcaggaat tgttaaaatt gaaatagaga attttgatac caatatgttt aagttggaaa
    66121 attatgtaaa agaaaaatat ggtctggaaa gtttagaaat tattccaaat gaatttgatg
    66181 ataatccaac aattttatct gaaagaattt ctcaagttgc agcaggtgtc cttaggaatc
    66241 taattgatga taatatgaaa attggctttt cttgggggaa aagtttaagt aatttagtag
    66301 atttaattca cagtaaaagt gtccgaaatg ttcacttcta tcctctagca ggtggtccta
    66361 gtcacataca cgctaaatac catgtgaata cactgattta tgaaatgtct agaaaatttc
    66421 atggagagtg tacatttatg aatgcaacga ttgtgcaaga aaataaattg ttagcagatg
    66481 gtattttgca atcaagatat tttgaaaatt tgaaaaatag ttggaaagat ttagatatag
    66541 ctgtagtcgg aattggtgat tttagcaata aaggaaagca tcaatggtta gacatgctta
    66601 cagaggatga ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat
    66661 tttttgattc aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg atagcaatct
    66721 ctttggaaga tttaaaaaat attcctcaaa gtttagctgt tgcttacggt gatacgaaag
    66781 tatcttcgat tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt acagacaaaa
    66841 atacaatttt aaaagttttg gaagaagatg gggatttgac ttttagagag attctaggtg
    66901 agtgaaaatg atagactgat tcagtttatc gtttttcttt ttagttgatt gcacatttgt
    66961 gcttatataa acaaaaatag tttatctgtt gtttttggat tgacaacttt attatgtagt
    67021 tgtattctat agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc tttttacata
    67081 gtgaaatgag gaggaattta tggaaattat tgttccagat caaattatca tgggtttaat
    67141 tttatatgct ggtgatgcga aacaacatat ttataaagcg ttagattaca taaaaaatgg
    67201 tacatgtgaa cggtgtgaag aagaaatcca gttagctgat gcagccttat tagaagctca
    67261 taatctacaa acaaaattct tggcacagga agcgtctggt acaaagacag aaattacagc
    67321 tctctttgtt cattcacaag atcatctcat gaccagtatg acggagatta atttaatcaa
    67381 agaaattatt agtttgagaa aagaacttca taaaaaataa tactagagta ttatcattgt
    67441 tattaacata gaggaggaaa acataatggt gaagattggt ttgttttgtg cagcaggttt
    67501 ttctactggt atgcttgtaa ataatatgaa aattgcagcg caatctagtg gagttgaggc
    67561 agaaatagag gcgttttctc agtctaaatt agcggattat gcgccaaata tagatgttgc
    67621 actattgggt ccacaagttg cttatacatt agataaatca aaagaaattt gtgataagtg
    67681 tgatgttccg atagctgtta ttccgatgat ggactatggt atgttagatg ggaaaaaagt
    67741 attagatttg gccctatctt tgattagtgg gtaagaaaag gagatttatt atgtcaaaga
    67801 tggatgttca gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt ggcattatag
    67861 ctctaaaaga tgggatgtta gcaattttgc cattgacagt agttggtagt ttgttcttga
    67921 ttatgggaca attgccgttc gaaggattaa ataagagcat tgctagtgtt tttggagcta
    67981 attggacaga gccgtttatg caagtatatt caggaacttt tgctattatg ggtctaattt
    68041 cttgtttttc aattgcctat tcttatgcta agaatagcgg agtagaggct ttaccagctg
    68101 gagttctatc tgtatctgca ttctttattt tgctaagatc atcttatatc cctaaacaag
    68161 gtgaggcgat tggggacgct attagtaaag tttggtttgg aggccaagga attatcggtg
    68221 ctatcattat aggtttggta gtaggaagta tttatacctt ctttataaag agaaaaattg
    68281 ttattaagat gccagaacaa gttccacaag ctattgccaa acagtttgaa gcaatgattc
    68341 cagcatttgt aattttctta tcttctatga ttgtatatat tttagcgaag tcattgacta
    68401 atggcggaac attcatagaa atgatttatt ctgctattca agttccgttg caaggtttaa
    68461 ctggatcttt gtatggtgct attggaattg cattctttat atcatttttg tggtggtttg
    68521 gtgttcatgg gcaatcggta gtaaatggag tagtgacagc tctgctttta tctaatcttg
    68581 atgctaataa agctatgtta gcctctggta atctatcatt agaaaatggt gcacatattg
    68641 ttactcaaca atttttagat tcatttttaa ttctatcagg ttcagggatt acgtttggtc
    68701 ttgtagttgc catgcttttt gcagcaaaat caaaacaata ccaagcctta ggaaaagttg
    68761 cagcttttcc agcaatattt aacgtaaatg agccagttgt atttggattt ccgattgtca
    68821 tgaatccagt tatgtttgta cctttcattc ttgttcctgt acttgcagct gtgatagtat
    68881 atggagctat tgcaacaggt ttcatgcagc cattctcagg ggtaacattg ccttggagta
    68941 caccagctat tctatcagga tttttggtgg gtggatggca aggtgttgtg actcagttat
    69001 tagtattggt gatatctaca gtggtttact ttccattctt taagatacaa gatcgtttag
    69061 cttaccaaaa tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt aaactcacac
    69121 atttgtgcta aaaattagag agttaaaatt tttctagtta aaagcttgaa aatttctata
    69181 aaaatcggta ttatattttc gaaagaaata aaaatatttt cgaaagaaag gtgcttacga
    69241 tggtaaatac agaagtagca agaacaacaa tcaagacaga atattttggc agccttactg
    69301 aaaggatgaa caaatatcga gaagatgttt taaataaaaa accttatatt gatgctgaga
    69361 gagcagttct agcaacacgc gcctatgaac gatacaagga acaacctaat gtcctaaaac
    69421 gtgcatatat gctgaaagaa attttggaaa atatgtctat ctatattgaa gaagaatcta
    69481 tgattgcggg aaatcaagct tcttccaata aagatgctcc tatttttccg gaatatacgc
    69541 tagaatttgt tctcaatgag ttggatcttt ttgaaaagcg tgatggagat gttttctata
    69601 ttacagaaga aacaaaagaa caacttagaa gtattgctcc gttttgggaa aataataatt
    69661 tacgtgctag agctggtgcc ttattacctg aagaagtgtc tgtttatatg gaaacaggat
    69721 tcttcggtat ggaaggtaag atgaattctg gagatgctca cttagcagtt aactatcaga
    69781 aacttttgca atttggttta agaggttttg aagagcgggc tcgtaaagca aaagtagctc
    69841 tagatttaac agatccagca agtattgata aatatcattt ttacgactct atatttatcg
    69901 taatcgatgc tattaaagta tatgcaaagc gctttgttgc tcttgctaaa agtttagccg
    69961 aaaatgcaaa tcctaaacgt aagaaagaat tacttgagat tgcagatatt tgctctagag
    70021 tcccatatga accggcaact acttttgcag aagctattca atcagtttgg tttattcaat
    70081 gtattttaca aattgaatct aatggccact ctctttcata tggccgtttt gatcaatata
    70141 tgtatccata tatgaaggct gatttagaaa gtggtaaaga aacagaagat agcattgttg
    70201 aacgtctgac aaatctttgg attaagacaa ttacaattaa taaggttcgc agtcaatcac
    70261 atacattttc ttcagcagga agtcctttat atcaaaatgt tacaattggt ggacagactc
    70321 gagataagaa ggatgctgtt aacccattat cttatttggt cttaaaatca gttgcacaaa
    70381 cccatctacc gcaacctaat ctaactgtac gttaccatgc aggtttagat gctcgtttca
    70441 tgaatgagtg tattgaagtg atgaaacttg gttttggtat gcctgcattt aataatgatg
    70501 agattattat tccttctttt attgcaaaag gagtattgga agatgatgct tatgattaca
    70561 gtgccattgg atgtgttgaa acggcagttc cagggaaatg gggctatcgt tgcacaggta
    70621 tgagttatat gaacttccct aaggttctac ttatcacgat gaatgatgga attgatccgg
    70681 cttcgggtaa acggtttgca ccaagctttg gtcattttaa ggatatgaag aacttttctg
    70741 aattagaaaa tgcttgggat aaaacactaa gatatttgac acgaatgagt gttattgttg
    70801 aaaattctat tgatttatca ttggaacgag aagttcctga tattctatgt tcagcattga
    70861 ctgatgattg tattggtcgt ggaaaacacc ttaaagaagg tggagcagta tatgattata
    70921 tatcaggatt gcaagttgga attgcaaatt tgtcggattc attagctgca attaaaaaat
    70981 tggtgtttga ggaagaacgt ataagcccaa gtcagctttg gcatgcactg gaaacagatt
    71041 atgccggaga agaaggtaag gtcattcaag aaatgttgat tcatgatgca cctaagtatg
    71101 gtaatgatga tgattatgct gacaaattgg ttactgctgc ttatgacatt tatgttgatg
    71161 aaattgctaa atatcctaat acacgttatg gaagaggtcc aattggagga attcgttatt
    71221 caggaacatc ttctatctca gccaacgtag ggcagggacg tggaacatta gcaactccag
    71281 atggacgcaa cgcgggtaca ccgttagcag agggttgttc accatcacat aatatggatc
    71341 aacacggccc tacatctgtt ttaaaatctg tttcaaaatt accaacagat gaaatcgtag
    71401 gtggggttct cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat
    71461 taaaactaat tgctttgtta cgaacattct ttaatcgttt acatgggtac catattcaat
    71521 acaatgttgt ttccagagag acgctgattg acgctcagaa acatcctgaa aaacacagag
    71581 acttaattgt tcgtgttgca ggatactctg cattcttcaa tgttctttct aaggcaaccc
    71641 aagatgacat tataggacgt actgagcata ctttgtaaaa taaagaggtt ctttttatgg
    71701 aatttatgct tgacacatta aatttagatg agattaaaaa gtggtctgaa attttgccgc
    71761 tagctggggt aacttcaaat cccactattg caaaaagaga gggttctatt aatttttttg
    71821 aacgaatcaa agatgtaaga gaattgattg gctctacacc ctctattcat gttcaggtga
    71881 tttctcaaga ttttgaaggc atcttaaagg atgctcatga aattcgaaga caagcaggag
    71941 atgatatatt tatcaaagta cctgttactc cagctggatt acgtgcaata aaggtgctaa
    72001 aaaaagaggg ctaccatatc actgcaacag ctatttatac agttattcag ggattattag
    72061 ctatcgaagc aggagcggat tacctagctc catattataa tagaatggaa aatctgaaca
    72121 ttgattcaaa ttctgtcatt cgtcaattag ctcttgctat tgatagacag aactctccta
    72181 gtaagatttt agctgcatcc tttaaaaatg tagcacaagt aaataatgct ttagctgcag
    72241 gtgcgcatgc tgttacagca ggagcggatg tttttgaatc agctttcgcc atgccatcta
    72301 tccaaaaggc ggttgatgat ttttctgacg attggtttgt tattcaaaat agtcgttcca
    72361 tttagataga gaggaaatac atatgagaat ttttgctagt ccttctagat atattcaggg
    72421 ggaaaatgcc ttgtttgaaa atgccaaatc aattttggat ttgggaaatt gccctattct
    72481 attatgcgat cagttggttt atgatattgt tggaaaacga tttgaagatt acctacatag
    72541 gtatggtttc catattgttc tggcgctatt taatggtgaa gcttctgaca atgaaatcaa
    72601 tcgagttgtt gccttggctg agaaagaaaa ttgtgatagt attatcggtc ttggtggggg
    72661 aaagacgatt gatagcgcaa aagctattgc agatttgatt gaaaagtctg ttattattgc
    72721 tccaacaatt gcatcgaccg acgcacctgt atctgcttta tctgttattt atacagatga
    72781 aggtgcattt gatcattatc tattttattc taaaaatcca gatttagttt tggttgatac
    72841 aaaagttatt tcacaagccc ctaagcgttt attagcgtct ggtattgcag atggtttagc
    72901 aacttgggtt gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt tgggacaaca
    72961 gcaaacattg gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg
    73021 tttacaggct atggcagctt gtgaagctaa agtggtgaca ccagcattag aaaatattgt
    73081 tgaagctaat actttattga gtggtctagg ttttgaaagt ggaggattag ctgcggcgca
    73141 tgcaattcat aatggtttta ctgcattgac aggtgacatt catcatttaa cacatggtga
    73201 aaaagtagct tatggaactt tagtacaact attattggaa aatagaccta aagaagaact
    73261 tgataagtat attgagtttt acaaaaaaat tggtatgcca acaactctaa aagaaatgca
    73321 tttggatcaa gttggatatg atgatttaat aaaagttggt aaacaagcaa ctatggaggg
    73381 tgagacaatt catcagatgc cgtttaagat ttcgccttca gatgttgctc aagctattat
    73441 cgctgtagat gcctatgtaa attcaaaata aacaataagg actactgttt tccaaatggt
    73501 agtcttttat tgatcctcgt attgaat
//
LOCUS       DBEJJE010000004        73093 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEJJE010000004 DBEJJE010000000
VERSION     DBEJJE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.04"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(207..689)
                     /gene="greA"
                     /locus_tag="ACL3F5_000247"
     CDS             complement(207..689)
                     /gene="greA"
                     /locus_tag="ACL3F5_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0514116.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(760..2415)
                     /gene="mltG"
                     /locus_tag="ACL3F5_000248"
     CDS             complement(760..2415)
                     /gene="mltG"
                     /locus_tag="ACL3F5_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0514117.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2496..2990)
                     /locus_tag="ACL3F5_000249"
     CDS             complement(2496..2990)
                     /locus_tag="ACL3F5_000249"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514118.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2987..3451)
                     /locus_tag="ACL3F5_000250"
     CDS             complement(2987..3451)
                     /locus_tag="ACL3F5_000250"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514119.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNLQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3461..4795)
                     /gene="murC"
                     /locus_tag="ACL3F5_000251"
     CDS             complement(3461..4795)
                     /gene="murC"
                     /locus_tag="ACL3F5_000251"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0514120.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4806..5423)
                     /locus_tag="ACL3F5_000252"
     CDS             complement(4806..5423)
                     /locus_tag="ACL3F5_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0514121.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5471..8569)
                     /locus_tag="ACL3F5_000253"
     CDS             complement(5471..8569)
                     /locus_tag="ACL3F5_000253"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0514122.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYIIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWETFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKGFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8662..9828)
                     /locus_tag="ACL3F5_000254"
     CDS             complement(8662..9828)
                     /locus_tag="ACL3F5_000254"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0514123.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHSVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSPYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9836..10930)
                     /locus_tag="ACL3F5_000255"
     CDS             complement(9836..10930)
                     /locus_tag="ACL3F5_000255"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0514124.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGSKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11088..11810)
                     /locus_tag="ACL3F5_000256"
     CDS             complement(11088..11810)
                     /locus_tag="ACL3F5_000256"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514125.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDEDSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            complement(11941..12771)
                     /locus_tag="ACL3F5_000257"
     CDS             complement(11941..12771)
                     /locus_tag="ACL3F5_000257"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514126.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISCGNLGFVFDLPLSIT
                     "
     gene            complement(12943..14901)
                     /locus_tag="ACL3F5_000258"
     CDS             complement(12943..14901)
                     /locus_tag="ACL3F5_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0514127.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(15105..16727)
                     /locus_tag="ACL3F5_000259"
     CDS             complement(15105..16727)
                     /locus_tag="ACL3F5_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0514128.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFLYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            16833..18278
                     /locus_tag="ACL3F5_000260"
     CDS             16833..18278
                     /locus_tag="ACL3F5_000260"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0514129.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(18324..18518)
                     /locus_tag="ACL3F5_000261"
     CDS             complement(18324..18518)
                     /locus_tag="ACL3F5_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0514130.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(18619..19268)
                     /locus_tag="ACL3F5_000262"
                     /pseudo
     CDS             complement(18619..19268)
                     /locus_tag="ACL3F5_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(19252..19764)
                     /locus_tag="ACL3F5_000263"
     CDS             complement(19252..19764)
                     /locus_tag="ACL3F5_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0514131.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(19850..20785)
                     /locus_tag="ACL3F5_000264"
     CDS             complement(19850..20785)
                     /locus_tag="ACL3F5_000264"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0514132.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGVNMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(20856..21155)
                     /locus_tag="ACL3F5_000265"
     CDS             complement(20856..21155)
                     /locus_tag="ACL3F5_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0514133.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(21145..21894)
                     /locus_tag="ACL3F5_000266"
     CDS             complement(21145..21894)
                     /locus_tag="ACL3F5_000266"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0514134.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(21948..22307)
                     /locus_tag="ACL3F5_000267"
     CDS             complement(21948..22307)
                     /locus_tag="ACL3F5_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0514135.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(22309..23709)
                     /locus_tag="ACL3F5_000268"
     CDS             complement(22309..23709)
                     /locus_tag="ACL3F5_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0514136.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTIFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(24004..24243)
                     /gene="rpsR"
                     /locus_tag="ACL3F5_000269"
     CDS             complement(24004..24243)
                     /gene="rpsR"
                     /locus_tag="ACL3F5_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0514137.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(24275..24745)
                     /gene="ssbA"
                     /locus_tag="ACL3F5_000270"
     CDS             complement(24275..24745)
                     /gene="ssbA"
                     /locus_tag="ACL3F5_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0514138.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(24757..25047)
                     /gene="rpsF"
                     /locus_tag="ACL3F5_000271"
     CDS             complement(24757..25047)
                     /gene="rpsF"
                     /locus_tag="ACL3F5_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0514139.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(25200..26546)
                     /gene="asnS"
                     /locus_tag="ACL3F5_000272"
     CDS             complement(25200..26546)
                     /gene="asnS"
                     /locus_tag="ACL3F5_000272"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0514140.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALEILERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(26562..26927)
                     /locus_tag="ACL3F5_000273"
     CDS             complement(26562..26927)
                     /locus_tag="ACL3F5_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0514141.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSERLIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(26920..28107)
                     /locus_tag="ACL3F5_000274"
     CDS             complement(26920..28107)
                     /locus_tag="ACL3F5_000274"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0514142.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAESRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKEAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(28104..28592)
                     /locus_tag="ACL3F5_000275"
     CDS             complement(28104..28592)
                     /locus_tag="ACL3F5_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0514143.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            28913..29461
                     /locus_tag="ACL3F5_000276"
     CDS             28913..29461
                     /locus_tag="ACL3F5_000276"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0514144.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(29739..30467)
                     /gene="yaaA"
                     /locus_tag="ACL3F5_000277"
     CDS             complement(29739..30467)
                     /gene="yaaA"
                     /locus_tag="ACL3F5_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0514145.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSLMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(30546..30710)
                     /locus_tag="ACL3F5_000278"
     CDS             complement(30546..30710)
                     /locus_tag="ACL3F5_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0514146.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(30889..32484)
                     /locus_tag="ACL3F5_000279"
     CDS             complement(30889..32484)
                     /locus_tag="ACL3F5_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514147.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDSKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(32496..32906)
                     /locus_tag="ACL3F5_000280"
     CDS             complement(32496..32906)
                     /locus_tag="ACL3F5_000280"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0514148.1"
                     /translation="MEKKIVKDILFLSQVSKPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(33022..33813)
                     /gene="yghU"
                     /locus_tag="ACL3F5_000281"
     CDS             complement(33022..33813)
                     /gene="yghU"
                     /locus_tag="ACL3F5_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0514149.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(33826..36522)
                     /locus_tag="ACL3F5_000282"
     CDS             complement(33826..36522)
                     /locus_tag="ACL3F5_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0514150.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            36826..38010
                     /gene="mntE"
                     /locus_tag="ACL3F5_000283"
     CDS             36826..38010
                     /gene="mntE"
                     /locus_tag="ACL3F5_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0514151.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEDRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(38153..40024)
                     /locus_tag="ACL3F5_000284"
     CDS             complement(38153..40024)
                     /locus_tag="ACL3F5_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0514152.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(40021..41220)
                     /locus_tag="ACL3F5_000285"
     CDS             complement(40021..41220)
                     /locus_tag="ACL3F5_000285"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0514153.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            complement(41217..41984)
                     /gene="dapB"
                     /locus_tag="ACL3F5_000286"
     CDS             complement(41217..41984)
                     /gene="dapB"
                     /locus_tag="ACL3F5_000286"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0514154.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(42250..43098)
                     /locus_tag="ACL3F5_000287"
     CDS             complement(42250..43098)
                     /locus_tag="ACL3F5_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0514155.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYPKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(43100..43474)
                     /locus_tag="ACL3F5_000288"
     CDS             complement(43100..43474)
                     /locus_tag="ACL3F5_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0514156.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(43548..44900)
                     /gene="glmM"
                     /locus_tag="ACL3F5_000289"
     CDS             complement(43548..44900)
                     /gene="glmM"
                     /locus_tag="ACL3F5_000289"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0514157.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(44924..45703)
                     /locus_tag="ACL3F5_000290"
     CDS             complement(44924..45703)
                     /locus_tag="ACL3F5_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0514158.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEIPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(45690..46547)
                     /gene="cdaA"
                     /locus_tag="ACL3F5_000291"
     CDS             complement(45690..46547)
                     /gene="cdaA"
                     /locus_tag="ACL3F5_000291"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0514159.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            46683..47651
                     /locus_tag="ACL3F5_000292"
     CDS             46683..47651
                     /locus_tag="ACL3F5_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0514160.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(47685..48596)
                     /gene="whiA"
                     /locus_tag="ACL3F5_000293"
     CDS             complement(47685..48596)
                     /gene="whiA"
                     /locus_tag="ACL3F5_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0514161.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHLYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(48593..49570)
                     /locus_tag="ACL3F5_000294"
     CDS             complement(48593..49570)
                     /locus_tag="ACL3F5_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0514162.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDDGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(49567..50457)
                     /gene="rapZ"
                     /locus_tag="ACL3F5_000295"
     CDS             complement(49567..50457)
                     /gene="rapZ"
                     /locus_tag="ACL3F5_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0514163.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(50509..50889)
                     /locus_tag="ACL3F5_000296"
     CDS             complement(50509..50889)
                     /locus_tag="ACL3F5_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0514164.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(50900..51487)
                     /gene="yihA"
                     /locus_tag="ACL3F5_000297"
     CDS             complement(50900..51487)
                     /gene="yihA"
                     /locus_tag="ACL3F5_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0514165.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(51496..52728)
                     /gene="clpX"
                     /locus_tag="ACL3F5_000298"
     CDS             complement(51496..52728)
                     /gene="clpX"
                     /locus_tag="ACL3F5_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0514166.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(52760..52930)
                     /locus_tag="ACL3F5_000299"
     CDS             complement(52760..52930)
                     /locus_tag="ACL3F5_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514167.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(52930..53436)
                     /locus_tag="ACL3F5_000300"
     CDS             complement(52930..53436)
                     /locus_tag="ACL3F5_000300"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0514168.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(53566..54084)
                     /locus_tag="ACL3F5_000301"
     CDS             complement(53566..54084)
                     /locus_tag="ACL3F5_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0514169.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(54580..56085)
                     /gene="lytC"
                     /locus_tag="ACL3F5_000302"
     CDS             complement(54580..56085)
                     /gene="lytC"
                     /locus_tag="ACL3F5_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0514170.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAYWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(56123..56881)
                     /gene="tpiA"
                     /locus_tag="ACL3F5_000303"
     CDS             complement(56123..56881)
                     /gene="tpiA"
                     /locus_tag="ACL3F5_000303"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0514171.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(56980..57657)
                     /locus_tag="ACL3F5_000304"
     CDS             complement(56980..57657)
                     /locus_tag="ACL3F5_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0514172.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(57666..58610)
                     /gene="metA"
                     /locus_tag="ACL3F5_000305"
     CDS             complement(57666..58610)
                     /gene="metA"
                     /locus_tag="ACL3F5_000305"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0514173.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(58792..59304)
                     /locus_tag="ACL3F5_000306"
     CDS             complement(58792..59304)
                     /locus_tag="ACL3F5_000306"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0514174.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(59391..60149)
                     /locus_tag="ACL3F5_000307"
     CDS             complement(59391..60149)
                     /locus_tag="ACL3F5_000307"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0514175.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            complement(60650..61780)
                     /locus_tag="ACL3F5_000308"
     CDS             complement(60650..61780)
                     /locus_tag="ACL3F5_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514176.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(62064..62149)
                     /locus_tag="ACL3F5_000309"
     tRNA            complement(62064..62149)
                     /locus_tag="ACL3F5_000309"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(62113..62115),aa:Leu,seq:aag)
     gene            complement(62231..62806)
                     /locus_tag="ACL3F5_000310"
     CDS             complement(62231..62806)
                     /locus_tag="ACL3F5_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0514177.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(62806..63594)
                     /gene="codY"
                     /locus_tag="ACL3F5_000311"
     CDS             complement(62806..63594)
                     /gene="codY"
                     /locus_tag="ACL3F5_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0514178.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            complement(63859..65433)
                     /locus_tag="ACL3F5_000312"
     CDS             complement(63859..65433)
                     /locus_tag="ACL3F5_000312"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0514179.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            complement(65632..66858)
                     /locus_tag="ACL3F5_000313"
     CDS             complement(65632..66858)
                     /locus_tag="ACL3F5_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0514180.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            67052..68368
                     /locus_tag="ACL3F5_000314"
     CDS             67052..68368
                     /locus_tag="ACL3F5_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0514181.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            68467..69810
                     /gene="murT"
                     /locus_tag="ACL3F5_000315"
     CDS             68467..69810
                     /gene="murT"
                     /locus_tag="ACL3F5_000315"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0514182.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEMVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            69810..70592
                     /gene="gatD"
                     /locus_tag="ACL3F5_000316"
     CDS             69810..70592
                     /gene="gatD"
                     /locus_tag="ACL3F5_000316"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0514183.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            70718..71800
                     /locus_tag="ACL3F5_000317"
     CDS             70718..71800
                     /locus_tag="ACL3F5_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0514184.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            71748..71996
                     /locus_tag="ACL3F5_000318"
     CDS             71748..71996
                     /locus_tag="ACL3F5_000318"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514185.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(72124..73093)
                     /locus_tag="ACL3F5_000319"
                     /pseudo
     CDS             complement(72124..73093)
                     /locus_tag="ACL3F5_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        21190 a        16539 c        13649 g        21715 t
ORIGIN      
        1 agctcaaaac atagttttga ggttgtagat gaaactgacg aagttagctc aaaacactgt
       61 tttgaggttg taaatgaaac tgacaaagtc agtaaccata catacggcaa ggcgacgctg
      121 acgtggtttg aagagatttt cgaagaatag caaaatggaa aaaggagtga gtgaagcaca
      181 tcgcctcccc actccttttt ctgtttttag gctgtttttt caaccttcaa gatttttaca
      241 tcatagctac caacaggcgt ttcaatggtt gctgtgtcac ctgttttctt gccaatcaag
      301 gcctgcccaa ttgggctttc atttgaaacc ttacctgcaa aggcatccgc accagctgaa
      361 cctacgataa tataaacttc ttcttcgtcc tcaccaattt cttggatggt gactgtttta
      421 ccaatcgcta cttcgtcctg ggcaactgcg tcgctattga cgatttcagc atagcggatt
      481 tttgtttcta agctagagat ttgtccttcg acaaaggctt gttcatcctt agctgcttcg
      541 tactcactgt tttctgaaag atcaccgtat gaacgggcaa tcttaatgcg ttctaccact
      601 tctggtcgac gaaccaattt caattcttct aattcttttt caagtttctc cttttcctca
      661 agggtcatag gatatgtttt ttctgccatt tttctcaact ttcttctgat aatattttct
      721 aaagaaaatt atgtgaagta tcacataatt ttagtttgtt tagtttaatt tgctgttgac
      781 atgttcagcg acattgcggt cgtggtcttc ttgattgtta gcatagtaga ccttgccttc
      841 tgtgacatct gctacaaagt agaggttatc gctcttagtt tgattgatgc ttgactcaat
      901 cgcatccaga cttggactat cgactggacc aggcatgaga cctacatttt tataaacatt
      961 ataaggtgaa tcaatgttgg tatcaatcgc aacatcctca gctagactga tattttgccc
     1021 cagttttcct tgggcataca agattgcaat attactttga agtggcatat cacgattcaa
     1081 acgattgtag aatacacctg caatgagctt acgatcttct gtcttggcac cttctttttc
     1141 gaccaaggaa gcaatggtca acaactcatt gacagtcaag tttttagatt tgatagtact
     1201 atagtaagga gataggttct tatccatagc agctaacatc tcatcaatca agctctcaat
     1261 agttgtgctt tccttgatag agtatgtagc tgggaaaagg tatccttcca aacgataacg
     1321 cgcaccgctg tcttttacag gcaaactttc cagtaaagta ggatatttcg ctactgcttg
     1381 actgataaac gtctcatctt gaactttagc caagaaagcc tccgctgtca aagactcttt
     1441 gaagtcacct tgcaattgac ccacagtttg agcaatctga tccaaggtat aaccttctgg
     1501 aattgtcaaa gtcgcaagta caggttcttg cggttcatct gttccacctt tttgcaactc
     1561 tttgagtaag tcttctgtac tcatactctt ttgcaaattg tagtaacctg ctttcaagtc
     1621 ggtataattt ttatacttgg cataaaaact aaaaatcaga ccatgcttta ccaaaccagc
     1681 tttttcaagc gtcgtaccga tttcttgaac gtttgaacct tctggaattc caaccgtcac
     1741 atatttctta gaattagcat cgataggtaa taaggaatct agcacgtact ggtaaccaaa
     1801 gtaaccacct gctgagagca aggcaaggaa tacaaggaat gaaatcacaa aagctttcac
     1861 atgtgacttc ttctctttct taggcttagc gggttttgct ccttctctac ggctacgacg
     1921 tgatgtatct ctgatgatat ccactgtttc tgtagcaggc gtaggtgttt ctggacctgc
     1981 ttgttctgct tttttctctg ccgtcgtata ggaaacagct acccttgttg gggtttcatt
     2041 gtattctctt tcaagtttct taggtctaac aggacctgga cctggtcttg atccactttc
     2101 ttccgctgga gaagaaggta catcttgact tggatgactt ggaacaccag gagtttctct
     2161 ttgaatctca tctgctggag aagctggtac accttgactt gggtgagtag gcacggtagg
     2221 agcttttctc ataatctcct ctaccgttga caaggaatca gccatgagtt cttcagctga
     2281 aggttcattt gcaggagtgc gaactactgc ctcatcttct ttcagaactt catcatagcc
     2341 ttttactttt tctaaatctc tcagaatctg ctctttaaag cttaatttct cttcttctct
     2401 tgacttttca ctcaaaagtt tttcctcctt gttgataatc cataatatta tatcttaaaa
     2461 gtccaaaaaa agcaatctat gatacttttc ctaacttatt ttttcatttc ccagaccata
     2521 tcataccatg tttcccctgc aaaggttgac tgggactggc cttcgttgac aaatccatgt
     2581 ttttcataat aggcgatgag atagtcatga caggttagat taatgccatc tctctcatct
     2641 tcaagagcaa cttctttcaa ggctgtcagc aatttctgac ccagtccgag tccctgtgcc
     2701 tccttggcaa tagacagaca ggtcacagag atataaccac caggctcatg actatagtct
     2761 tttatttctt ctgtaaaaga ctggtcttgc agatggcggt gcaggccaac tggtccttcg
     2821 atataaccca tgattcttcc ttctttttca gcaaccagaa aagaggtctg aatttctctc
     2881 aaatgtgctt caaagacaga aggaggaatg gcttcttcga ccgaaaaatt ttcaaattca
     2941 agttcaacaa tccgatccaa atcttctaat cttgcttgtc tgattttcat tgttcctcca
     3001 gataaaaggg attaaaccaa atcatactat agccctggct agttgcatag agcaaagttg
     3061 cttcttcatc aacaaaaccg ttcatttcaa aataggaaag cagctcatca ggactctcca
     3121 aacgaatccc tttgtaatcc agctcaactg ccacctcttt caaggctgca agaagaagtg
     3181 ttcccaggcc ctgtctctga tggtcagact cgatgactaa agaatgtact tttagacatt
     3241 gcagattgtc tgactgggga cttgataaaa tatagcctaa aagttgattt tcatccctag
     3301 ctagaagaaa ggtatccgca cacttacgga tactttcttc taaaatatgg gaaagttgct
     3361 gcttttcagc tggaaaagac gaggtctgaa gtgcccctat ctcaggcaaa tcagacttgc
     3421 ttgcctgaat gatcttaatt ggaatttcca tgggaacatc ctattgaaca ttgcttgtca
     3481 agttagacaa gagacgctca aatgagtatt cataggtttg gatgtctcct gctcccataa
     3541 agacgtaaac agcattgtca tggtctagga gtggagaaac attttcaaca gtaatcactt
     3601 ggtgtttttt gttgattttg ttggctaggt cttctacctt aacgtcacca tgatctactt
     3661 cacgagccga gccataaatt tgcgctagat aaacagcatc tgcttggttt aaagcatggg
     3721 caaagtcgtc caacaaggca atggttcttg taaaggtatg cggttgaaag actgctacaa
     3781 tttccttgct tgggtatttc tgacgagccg catccaaggt cgcaataatt tctgttggat
     3841 ggtgggcaaa gtcatcgata atcactgtat cattgacaat tttctcagtg aaacgacgtt
     3901 taacaccggc aaatgttttc aagtgctcac gcaccaagtt caaatcaaat cctgctgtgt
     3961 aaagaagacc aataacggct gtcgcattca tgatattgtg acgaccaaag gttggaatgt
     4021 ggaattgccc caagttttgt ccacggaaat gaacggtgaa ggttgaacca gttattgaac
     4081 gaagaagatc actagctaca aagtcattgc cttcagcttc aaaaccataa taataaattg
     4141 gtgcatcaga cgtaatctta cgcaattcag catcttcacc atagacaaaa agacccttgg
     4201 tgatttgttt ggcatagtcg ttaaaggcat taaaaacatc ctcgagactt gtgaaataat
     4261 ctggatggtc aaagtcaatg ttggtgataa tagagtattc tgggtggtaa ggcatgaagt
     4321 gacgctcata ttcgtcagat tcaaagacaa aatatttggc attggccgaa ccacgacctg
     4381 tcccatctcc aatcaagaag ctggtatctg taatgtgaga caagacatga gacaacatac
     4441 ctgtcgttga agtttttcca tgtgctcctg ctactcccat gctaacaaag tcacgcataa
     4501 agctacctag aaactcatgg taacgtttgt agctgatacc attttggtcc gcataggcaa
     4561 tttcgacgtt gttatctgga cgaaaggcat ttccagcgat aatttccata tcaccgtcta
     4621 gatttttttc atcaaaagga agaatggtaa ttcctgcctg ctcaagaccg cgttgggtaa
     4681 agtagtactt ttcaacatct gatccctgaa ccttgtgccc catctggtgc aacatcaagg
     4741 ccaaggcact catccctgat cccttaattc cgataaaatg atatgtcttt gacatgtttt
     4801 ctcccctatt ctgtcattct ggtcagattc aactcttggg caacccgacg ttcttgttct
     4861 gtttgtttac tttttttatt gtagatttgg ctcttcttta gaaaatcata attgtttttc
     4921 tttggagcag gtgctgacac ttcttcattc ttggtaggga tagaatgaac ttcttccgcc
     4981 aagatataat gagactgggt caatttttgg ctatatttga caaattcacc aggattttcc
     5041 ttttggaaag gagctgtcgg ttgattgccc tgtctaacta gactgggctg agaatgacgt
     5101 ctcgcaaggc tgaaatcctg agttaggtag ttagcagagc gtttcttttt caagtccgca
     5161 cgcgcttctt cacgcgccac ctccgcatag ctctttcctt cttttttaac ccctaaagga
     5221 gcctttttag gtttttcgac ttgcttttca atcggtttta ctggtttttc ttcagcaata
     5281 ggagcccatt ctaaataatt tttatctcga tactcaccct tgatattact gatcagatca
     5341 gactcatcat agagattcat gactggcatt tcagtcaaca tgacctcgtc atctgacacc
     5401 aatggaaatc gttcttgttt cattttctat ttcctttcaa cacttcatta tagcgtattg
     5461 tcttgatttt tcaagtgctg gcttcagaaa ttcccaaaat ttctctaatt tctgctaggg
     5521 tcagactacc acgtgactct gtgccgtcca atacttgtga caccagatgt ttcttttgtt
     5581 cttggagttc ctgaattttt tcttcaatgg ttcccttggt caccaagcga tagacctcaa
     5641 ccgtttcttc ctgacccatc cgatgggcac ggccaatggc ttgcgcttcc accgcaggat
     5701 tccaccaaag gtcaaccaag atcactgtat ctgcacctgt caggttcaga ccgaccccac
     5761 cagccttgag ggaaatcaga aaggcatctc tttctccttg gttaaaggcc ttggtcatgt
     5821 cttgtctttc cttggctggg gttgaacccg taattttaaa ggaagtcagg cccaagtctg
     5881 gcagttcttg ttcaattttt tccaacattc ccttgaactg agagaaaatc aagacacggt
     5941 gtccgccgtc tgccacctgt accagtaggt ctcggagact atctagtttg ccgctggctc
     6001 cctgataatc ttccataaac agggcaggag tgtcacatat ttgacgcaag cgcatcaaac
     6061 cagataaaat ttccacacga cttcgctgaa attcctgttc tgacacttga gccagatggt
     6121 ctcgcatctg ttgtaactgg gcaaggtaaa tagccttttg ctggtcttcc agttcatttt
     6181 tataaaccac ctcaatcaag tctggcaatt cagtcagaac ttcttctttc ttgcgtcgca
     6241 tcacgaaagg cttgataaac tgagccactc gctctgctgg caatttcata aatcctttct
     6301 tgcttggcaa aagtccaggc atgacgattt gaaaaataga ccacaactca cccagatggt
     6361 tttcaatcgg agttcctgac aaggcaaaga ccgacggcac cacaaattgt ctcaaggtct
     6421 gggcaatctt ggtctgggca tttttcatga cctgagcttc atctaagaaa aggaagtcaa
     6481 aggccatccc ctgataaagc tcactgtcct gacggaaggt ggcatagcta gtcacataga
     6541 tttgatggct ctcggcaaga atctcctcac gacttgcttt caaaccatga acaacagcca
     6601 catccaactg tggagcaaat ttctgaaact catctgccca gttgtaaatc aaacccgacg
     6661 gagcgagaat caaaacccga ctttcttttg tcacttgact agtcaaaaaa gcaatagtct
     6721 gaagggtttt cccaagtccc atatcatcag ccaaaatccc accaaaacca taatgatgga
     6781 gcatctgcaa ccagccaatt cccttttcct gataatctcg caagtcagcc ttgacctgag
     6841 ttgcttgcaa aggaaagtcc tctggatgcg tcaaatcctg ggccagattc tggaattctt
     6901 gtgaaaaaga aacacggtct cgcccttcaa agagatgagc taaactgtag gccaaggatt
     6961 tccgagcctg caaggtccca tcttttaatt caaattgccc cagttcctgt agattttggc
     7021 gaattttctt ggtttcttca tcgaaaaagt aaacttgatt agacgaatca atataaaaat
     7081 cctgattggc aaccaaggcc tgcatggctt ggtcgatttc ctcctgggca atattttgaa
     7141 aatcaaactg gatttccaag agacctccct tggaggcaat ctgcacctga ggactcgcta
     7201 ggctataaag ctcttctagt ttatctgata ggtcaacatg cccgagtttt tcaaagactg
     7261 gaatgatatc atgaaaaaaa tgatagacag actccgcttt taaggcctga cgccaagatt
     7321 gaaaatcggc ttcaaagccc gcagccaaac agacttggaa aattctttct tctaagtctg
     7381 cgtcacttga aaagggtaat tcttctagct cttgtcggct agatacctgt ctatttccat
     7441 aatcaaactg aatttctaaa cgaatccgat tatcttcttc cctgtcaaag taaaaagagg
     7501 gcgcaaaagt tttgatttgt agacgttctg gagctgaaac ggtgcccatc tggataaaaa
     7561 gagtcagaca ggaggccaat ttgtctcgat cactgctatc aaattgcagg tatttctttc
     7621 cttgttgacc cacaggtaac gctttaattt ccttgagaag acgcatctgc tggtctgtta
     7681 aaaaataaac ctgaccttta tggaaaagta ctgctccctg ataaaagaca ttgaccctag
     7741 gactctcact gatttccatt tcaaaataat ccgagtattc tgttactgca aaggcaaata
     7801 gattggcatc agcatgcata tcctgaaaaa gcagggtttg gtagctatcc acttgatggt
     7861 caaattgaaa atggggcaag gccatcagta aattcacacc ctgctcaaaa aaggtcagag
     7921 ggaaaaagag gtgccgacct tggttttgga aaaagaggtc tggaaccagc ccttcctccg
     7981 ttagtccgtg caagaaagtc aaaagttctt ggctggcatc atcaaaggtt tcccaagaaa
     8041 gagactcctc ataaatcttg ccaatcatat acgactttct ctgctcgaca atccttaaaa
     8101 aaagtggaat atcccgaatg atatagtatt tttggctatt gatttggccg attctcagag
     8161 tccacaagat atgattggtt cctgcttcca cctgacccac agctgataac tcataggcgc
     8221 attctgattt tggagataaa attcgatcca aaaacttgcc acccaaggtc accttggttt
     8281 caacggcctc tttttcttca tgaccttctt ccagactcca caagatttcc tgaccacgct
     8341 catcattttt cagaaaatgc tctagcgctg ccaaatgcac acagtaaccc ctcttttgaa
     8401 aaaaatcaca ggcacaaaaa accaaatcat cctctaaact atagcgcagt tcttcttctg
     8461 caacgcgagc gtagagccga ttgttctttt ccttgatgat atcaacctta ccagtttcat
     8521 aaagggcaac accttcgata cgaactttcc ccggaatcaa tttagccata ttttcacctt
     8581 taccttatct ttttattata ccatattttc gcctatgaaa atagccttct aggaagactt
     8641 ttctcctaga aggctggatt tttaacgttt ggcaaaagta gccacaatcc gctgacagac
     8701 ttcttgcaac agagatttgg gcatagctat attgatgcgg gcatggagac ttccttcctc
     8761 tccaaaatcc aaaccacggt tgaggataac cttggcttca tttctcaaca actcttgcaa
     8821 tgtttcatca gtcaggtcat aaggtgaaaa gtcaagccaa atcaagtagg taccttgcgg
     8881 tttcatgacc ttgattttag tctcttttcc aaatagatcc atcacataat tgatgtggtc
     8941 ttcaaagact tgcttgagtt cctctagcca atctttaccg tatcgatagg cagcttctgt
     9001 cgccaaataa cccaagcctg aaatttcatg ctgattattg gccaacaggc gtttctggaa
     9061 agccagtctc aacttaggat tttcaatgac tgcataggaa ttttttgttc cagcaatatt
     9121 aaatgtttta gtggcactac tcaagacgat agcaaaattt ttgaaggcag gattgatggt
     9181 attgaaagac tggtgtttgt gaccaaagag ggtcaaatct tggtgaatct catccgaaac
     9241 taacaaaaca ctgtgttttt ggcagagttg gccaatcttc tccaacactt ctttttccca
     9301 aacacgtcca ccaggattgt gagggttgca aagaacatag agtttaacct cctcttccac
     9361 caaatccttt tcaagttggt caaagtcaat ctcaaacaga ctatcctttt ccactaagga
     9421 attagtaatc aatctacgat tattcaactt gacactgcga gcaaagggtg ggtagacagg
     9481 cgtgttaatt aaaaccgcct cgccttcttt tgtaaaggtt tgaatagctg ttgagatggc
     9541 tggtaccaca ccctcgataa agacaagagc ctctttgtca aagttataac cgtattgtgt
     9601 agcttcccac ttttgaactt ccttaattaa gtcttcactg gcataggtat aaccataaac
     9661 cagttggtct gcgtaagttt gcacggcttg gcggatttca ggcaagacca caaagtccat
     9721 atccgctatc caagctggta gaacttcact atccgtttct gtttctttcc atttataggt
     9781 atggtgccct aaacggttgg gcaggcttgt aaaatcatat tttcccatct ttgtcttatc
     9841 cttctaaggc ttggcgcaaa tctgcaatca aatctctagc atcctcaatc ccaatagaca
     9901 aacgcaagag gtcatctgtc aaaccataag aatggcgtac ttctgctgga atatcagcat
     9961 gagtttgagt cgttggataa gtaataagac tttccactcc gcccaaactt tccgcaaaag
    10021 agaagacctt gagactgttc aaaatatgag gaatgcgtgt ttcatcggct actttaaagg
    10081 aaatcatgcc tccacgacca gtgtagagaa cttccttaac tgctggagaa tccttcaaaa
    10141 aggcaaccac ttcttgggcg ttagctgttg agcgctccat acgaagagac aaggtcttga
    10201 gaccacgaag caactggtag ctgtcaaatg gagacaagac tgcccctgtt gtattaagat
    10261 tgtaaaaaag cttctcgtat agctctaaac tattggtcac aaccactcca gccaagacat
    10321 cattgtggcc tgctagatac ttggttgctg aatggagaac gatatctgct ccatcttcaa
    10381 tcggacgttg gtagataggg ctatagaagg tattgtccac caccactttg gaacccttag
    10441 catgagccaa ttttgctagt ttttcgatat caaattccaa catcaaggga ttggttgggg
    10501 tttcgatata gagaacatcc acatcctttt ctaactcggc aatcaactct tcttctgtat
    10561 tggcataggt aaaatggaaa tgaccttcct gctccacttg gttaaaccag cgaaaagaac
    10621 caccgtaaag atcacgcact gccaagacct tacttcctac tggaaagacg ctaaaggcca
    10681 gtacaatagc tgacatccct gagctagtcg ctagggcata gtctgctgac tcaatagccg
    10741 ccaagacttc ctcagcctta ctacgagttg gatttttagt gcgcgtatag tcaaacccag
    10801 tagatcgacc aaactctgga tgctgatagg tcgttgaaaa atgaagtggt gtcaccaaag
    10861 cacctgttgc ctcatcagac ttgatccctg cttgtgctaa aattgtgtta atgtgtaatt
    10921 ccttgctcat acaattcctc caaatctata gtaactattg taccacttat tttcatcaac
    10981 tcattttctt cttttcaaga gctagttata gtttcaaact atataaaaag ggagtttttc
    11041 ctgctccctt taatagacta taaaatggtg aatctcaaaa gacaccttca ctctatcatt
    11101 tgctcctgca caaaacgagc ataacgctca tgattttcca gtagttcctt atgagttcct
    11161 gagccagtga ttttcccctc ctctaagaag aaaatacaat ccacatcttt taccgttgac
    11221 aaacgatgcg ctataatcac aaccgtcttc tcctttagta cagaatagag gctactgata
    11281 atcgcatact cagaatcctc atcaagatta gcagtggctt catcaaatat aagaatttca
    11341 gcatctttta agtaggctct agctatttga agtctttggc ttcgcccccc tgacaagagt
    11401 cgtccgcgtt caccaacttc agtatctagt ccctctttca tggagcgaat ctcatcacct
    11461 agtgatacta agtctagcac tttcatcaat tcatcatcag ttactaagcg attcaaaccg
    11521 agacaaagat tgtcacgaat actgccagat aagactgcat tattttgtga aacccaagcg
    11581 attttacttc tccattcttt taagttaaaa tcatatatac ttgattgctc cattagaata
    11641 tctcctgaaa gcggtttata aaaccgctct aacaaacgca caatcgttga ttttcctgat
    11701 ccagatggcc caacaaaagc aattttttgc cccttgaaaa ttgaacaagt aatatccttt
    11761 aagacaggtc gattttcatc ataaccaaaa tagacatggt taaaattcaa cccttgtcct
    11821 gataccgatt ttcctccctc aaatttttct ttaggaactg caagcaagtt ctccagtgca
    11881 actgaagatc ccttgctact agaataaata gttacaaaat tagctatatt actaatagga
    11941 ttaagtaatt gaaagaggta aatcaaaaac gaaaccaagg ttcccacagg atatatatcc
    12001 tgcgctgacc cgataacccc cataggttag catcacaact atagtcgcaa agataaataa
    12061 gagagcaaac ggggtctcaa aagaagtaac cctatctgat ttcagtgaat tgttttgtac
    12121 cctttcaata caattatcca aaacatcctg tacacttttc tctgcttggt tagtcttaat
    12181 taattcatgt tcttgaatct tttcagtcaa ttgccctgtt aaaaatccga tttcctcctg
    12241 taaacgacga ctatactttt cactgatatt ggaaaggggc aagataataa acatcataca
    12301 aggaagagtg atgaataaaa gtagagaaag attccaatca agactaaata agactacaat
    12361 ggaaccaagt accataacta aactcagaat aatatttggg aaagtcgtaa ttaaaaactc
    12421 acgaatgaca ctcgtgtcat tgacaatggc agaagtcaac tccccacttt ggctcttatc
    12481 aaagaaggat ttctctgcat aaatcaaccc ctctatcact tttttcctga tttttgctat
    12541 ctttttttca cccgattgac taaacagata gtaaccaata gaagaaaaca aggcttgacc
    12601 aataaaaatc aaaaacgatt gaaatacttt ggaacctata ttttcaatag aactcccatc
    12661 tattaaaccc tttaagataa ggggaagcaa caaagcaagt agactagaca gaacaaggaa
    12721 gaaactcccc ataatcacct tagtatctac tcttaataat tttaatttca taaatactcc
    12781 ttataatatt tcaacggata aagtcgggaa taactcaatt tgaggataaa atctaataaa
    12841 tcttcctata acaaaacgca taacatctag gattttatat acctgatatt atgcgttttt
    12901 aagcacaaag acttcttaca caaacttatc tacaattaga ttttatttga catgttttgc
    12961 caattcttct tgggcttttt tattggattc ttctttttct ttcaaccatt tttctctggc
    13021 ttttgcatat tcgtctgttg tgacaatctt atcttgtact ttgaggtatt tatatgattc
    13081 aacccctttt gtaccggtta aaccataggc agcagcaaat ggtacggttc ttctcaatga
    13141 tggtgttccc ccacgcgaaa cacttggaag aactaaagaa ctatcaatca accaagcttg
    13201 aatatcagca tatttctcat aacgtttggc tggatcttgc tctttattag cttcttccaa
    13261 catttgagta tagacatcca gtccaacttc cttagccttg tcattggctt ctccaggctc
    13321 tagtccaaga ttttgtagaa ctcctccact attagtatta aaaatatcga gataggttga
    13381 cgggtcttga taatcaggtc cccaaccgcc atgatataaa tcatagtctt tctgagcagc
    13441 tgtttgagca aagtagcctg aactgtcaaa ctcatctgat gttaattgct gaatgtcaat
    13501 cactacatta tcagaaccta aaacagattc aattgattgt ttgatagaac taactccttg
    13561 tatgcctact ttatctgtta cttccacagt cttatccaag tggattggga attgaacacc
    13621 ctttgcttcg agttctttct tagcttccgc aaacttagcc ttggctttct caggattgta
    13681 gtaagggtct tgaccatccg caaagttgat accttgccat tccttaccat agttgaccat
    13741 cttagaggct acaacttcac caaagtcttt tcccttgata ctgacaaagt ttggaggaac
    13801 cactaggtta cgcaaaatct ttgttgcacc ttctttccct tcagactgag ccccataaga
    13861 tgttctgtca aaagcaaaat tgatagcctg acggaagttt ttattgagaa ctgcttcctg
    13921 agtcgatttc ttttcaatgt cacttgtttt agaagtataa ttgtaagact tcctatctag
    13981 gttaaaatta aagaaatatg aagttgaatt ttgcatacta tagatgatat tgtttttgta
    14041 tttttcttta atcccttcat agctggagct gttaggaaaa agacgagccg tagtataagc
    14101 accagctgta aaattacgtt ccagtgattc ttggtcgcta ccatcatagt aggtcaattt
    14161 cacatcgtct acaaagacat tcttagcatc ccagtaatta gggtttttct tatattcaat
    14221 agcagatttt gagacaagtg ctttcatcaa gaaaggtcca ttgtacaaaa tactagatgg
    14281 atccgccttc ccaaaatcat ccccttttga tttcaggaaa tctgcattaa caggaaaaag
    14341 tatcgttgca agtgtttttg aattccagta aagttctggt ttaaccaaag tatattgaac
    14401 cgtttggtca tcaagtgcct tgacaccgac agttgaaaag tcgcttgttt taccagtgat
    14461 atagtcatcc aaaccagcaa cagagtcctg cactagatac aaggcttctg attttttatc
    14521 agctgcatat tgcaaacctg tcacaaaatc ctgggcagtt acaggcgcat attcttctcc
    14581 ctcagaagta aaccacttgg catccttacg aagtttgtag gtataggtca aaccgtcctg
    14641 agaaacagtc caatcctctg ctaatgatgg aataatattc ccatattggt cattttctaa
    14701 taacccgtct accaaatttg caacaatatc ggatgttgct gcgcggtttt ctgctagata
    14761 gttcaagcta gatggatcac ttgaataaac atagttgtat gtttttgacg ccgtgctaga
    14821 atttccacac gcgctcaata aaactcctgt acccaggaca agacctgcca aggttagata
    14881 tttgctctta gactttttca tttccggaac ctcctgcttt aaatatttgt tttattatac
    14941 aacatttagt ttgtttagtc aatgattttt tccaaaaaat cgaaaaaagc ctcattttct
    15001 atttttgaaa tataatttta gctattttta cgctaaaaaa ggaataagct tcaagttctc
    15061 ctaaaagatt gttcaactta ttccttttat ttataaatgc taccttacga aagcttaaat
    15121 tttgctcgca ggcgatctgc ttgggctttt cctattacct tatctaataa ataggtacgc
    15181 agactcataa ccatataaag tccacccccc atggcaccga caagagctac ataaaggaag
    15241 ctccacaaac gtccacttgg ttggaagaaa aatcctaaca gccactggat ggttcctatt
    15301 aacagaaaca tgactagggt cagcaaactg attaaaatgg ttcgcttcaa aatcaccttg
    15361 cgcttgacac cagttacttt acaaatatcc cgatacatca agacgttagg aatgatgaga
    15421 gcaatggttg ttgaaatcaa aggaccataa ctgtggaaga gggcgatggt aggtagttgc
    15481 aagactagct tggcaataga accatagata aaatagagaa cggccttgcg gttgcggaac
    15541 atggcctgaa gcattggaga caagaccatg tacaagccta aaataataga ctgcaaaact
    15601 gcaaagacaa ataagcccag agccaaacta tctggcttac catagaagac cgtataaaga
    15661 ggttctccta ccataaccac tccaaccgtt gctggtagca agaacataaa gagtagggtg
    15721 agactgtcct gaacgagacg agaagctgct ttcaagtccc ccttgacata gttttccgtc
    15781 aaaagtggca aaccaacact cccaatcgaa acccctacag aaatcaaaat catcgtgatt
    15841 ttattaggat tggctgagaa ataagaaaac atgacaacca agtcctcatt gctgtagttg
    15901 gtaaaccagc tcatactatt gataaaggtc agctgatcca aaatctggaa gagctggatg
    15961 gcagaccctg tcaggataaa aggaatggct tccttaatgg tatcaaccaa gagacgctta
    16021 ctgttaatct tatctcctgt ttcaaagact cttttgagtg aaccttcttg ggcaaggaaa
    16081 taaatcaaga ctgcaaaact ggctaccata ccgacaaagg cagcaaaggt tgattgggta
    16141 acggctgcta gataatctcc tgaaccgagc ttcataatga taaaggttgc taggagcatc
    16201 cagataacac gaatgacctg ctcagcaatt tggctcatgg catagggttt gaggttattc
    16261 atcccttgga aaaatcctcg gataacactc atagacggga aaatcaagac tccccaagcc
    16321 aagctttgca tgattgggat caagtctttg cccacgccag acaagtctgc tagccaagga
    16381 gcaaagacat acaagactaa agcaaaaacc aggcctagtc ctgtcataaa gcctaagaag
    16441 ctccgaatca gggcaaagct atgctcttct tctcgcatgg tattatactt ggcaacttgc
    16501 ttggccaccg caactggaat ccccgctgtt gaaaccaaca agaaccaagc atagatattg
    16561 taacccatgg taaagagacc atttgcctta gctgcataag cccccatcca gatgtaccaa
    16621 gggataatgt aaacagcccc gagtaggcga ctgataaagt tactagccgt tagccaagca
    16681 gtcccccgta acatctgggc ctgctggtga ttgttttcgt gcgacataga ttcctcattc
    16741 aattttgata actaggaaaa actccttatc ttccattata aacttttcct tgttacttgt
    16801 aaatttgcga ctttcggttt acaatagaaa gtatgataaa aattgaaact gtattagata
    16861 ttttaaagaa agatggcctt tttcgcgaaa ttattgacca aggtcattac cactacaact
    16921 acagcaaagt tgtttttgat agcatcagct acgacagccg aaaagtaaca gaagacactc
    16981 ttttttttgc aaaaggcgct gcctttaaaa aagaatacct tctttctgct ataacacaag
    17041 gcttagcttg gtatatagct gaaaaggact acgaagtcgg tatccctgtc atcattgtga
    17101 acgatataaa gaaagccatg agtttgattg ccatggagtt ctatggtaat ccacaggaaa
    17161 aactcaaact ccttgccttt actggtacta agggtaagac aacagcagcc tatttcgcct
    17221 ataacatctt atctcaaggg catcgacctg ctatgttgtc gaccatgaac acaactcttg
    17281 atggagagac tttctttaag tcagcgttga caacccctga gagtattgac ctctttgaca
    17341 tgatgaatca ggctgtgcaa aatgaccgta cccacctcat catggaagtc tccagtcaag
    17401 cctatctggt caaacgtgtc tatggtctaa cctttgatgt gggagttttc ctaaatatca
    17461 gcctagacca tatcggcccg attgaacacc ctagctttga agactatttc taccacaagc
    17521 gtctcttgat ggaaaatagc cgagcagtca tcattaacag tgacatggac cacttctcag
    17581 tcttgaaaga acaggttgaa gatcaagacc atgatttcta tggtagccaa tttgataacc
    17641 aaatcgagaa ttccaaagcc tttagatttt cagctacggg taaactcgct ggagattatg
    17701 atatccaact cattggcaac ttcaaccaag aaaatgcagt tgctgctgga cttgcttgtc
    17761 tccgtctcgg agcaagtctt gaggacatca aaaaaggcat cgctgcaacc cgcgttcctg
    17821 gtcgtatgga agtcctcact cagaaaaatg gagccaaggt cttcatcgac tatgcccaca
    17881 atggggatag tctgaaaaaa ctcatcaatg tggttgaaac tcatcaaacc ggaaagattg
    17941 ctctggttct gggatcaaca ggaaacaagg gagaaagtcg tcgtaaggac tttggcctcc
    18001 tcctcaatca acaccctgag attcaagtct ttctgactgc tgatgaccct aactatgaag
    18061 acccaatggc cattgcagat gaaattagta gctacatcaa tcatcctgtt gagaagattg
    18121 cggatcgcca agaagccatc aaggcggcaa tggctatcac aaatcacgaa ttagatgcag
    18181 ttattattgc gggtaaggga gccgattgtt accaaatcat ccagggcaag aaagaatcct
    18241 acccaggaga tacagccgtc gcagaaaatt atttataaga atagaaaaaa tcaagggaaa
    18301 atgaaaccct tgattttttc ctattattta gtaaaaacgt ttttcaaacc ttcaacggca
    18361 ccttctacag caccttttgc gtcttctaca acgtcttttg ccttagcaac tgttttttca
    18421 acagctcctt caagttctgt cttgctgtct ccagtaactt taccaaaacc ttctttgaca
    18481 gcgcctgttg cttgttccaa tttgttttca agtgacatat gattgtctcc tttagtttat
    18541 tccgatatgt gttaccggtt acatatagtt tataccgaat actaaggaaa gtcaaacaat
    18601 gtactcagaa acaagaaatc acgctaagta gaaagttaac ctctccttat caaaatcgat
    18661 agccaactca tactttccat cttcattttg cacaatatag cctaagacaa cctaactgtc
    18721 cacaaagata tcacggcatt tctgcataag ctggtctttt ttgagaaatt tcaacaaaaa
    18781 agccgtcata tacttgaggg catactcagg attaacatct cctaaaatgt catagagctc
    18841 ctgctgtttt tctgtcaaag gatactgctg tttgaccttg taaaaataat tggacagggt
    18901 cattttaatg cgcgcaaagt ccgtcttttc aactaaaata gctgcattga tttgattgcg
    18961 caattccgtc tcaaaactct gctccaacaa ggcttgatag accggactag cttctctgac
    19021 aaaaatctct tgatccagtt caagactatc aagtgattca agcgtaggaa aattgaggta
    19081 atagcgctta ttttcacgta gaatcaagcc tgcctttata tactcttcca tgagtttatc
    19141 aactgcaaca tctggaaatt gagccttaat ttcccgtaga atcacatcct catactgatc
    19201 cagatagcgg atcaattctc caaaaatggc tgtctcgtca aacgagatgg attaaaaatc
    19261 tgaatcatga agattccttt ctttacattg taacagaggc gatgctgcca actgactagg
    19321 attggtacca gcttggttca gaggaacagg cagacctagt tctatgtaat actccctcca
    19381 aaaatcacta atctcctgct ccccatctcc aaatttcata ggaatagttt caaaaatagg
    19441 taggatttct gctatatact gggagcagta aaaaccagct gcatctggat agaaagaagc
    19501 attgtagggt gctccaagat gtttgcaagc tctttccttc accgactgga tatccatttc
    19561 tgggtaaaca tagaggtcgt ataaatgatt ggactcaaag aagtctgccg gttcttgaca
    19621 gacaacacca gcctgtccac tagcatgata aatcatccca tccaaataaa tggcaacatg
    19681 gctatagtta cctgtggaag tctggatggc ctgtcccatg tctgacccat ctctcacaaa
    19741 aatcaaatcg ccattttcta acatacttca ctcctagaaa aaaggagccg aaactccttt
    19801 cgatataagg caaactagac tttccgattt tgagctgaca cccaaaatct tacgcattaa
    19861 agctttcagt caattgaggt accacttgtt tcttacgtga aacggcacca gcaaggaagg
    19921 catgattgtt ttcaagtttg aagttgaaag ccgcttcgac cttgtccata ttgacaccaa
    19981 gagccaagat ttctgagttt gagttgacga tatctgtaat catcaagaca aagtcagagt
    20041 agccgtttga ttcgttggca gcttgcattg cagcttcaat ttctgcttgg cgttccaaaa
    20101 cttcagcgat gtcaactgtg ttcacttggg caacacggac attatttccg ttgagttcaa
    20161 aagtcttagc atcgatgtca atcaattctt cagcagattt gctagccaag ttggtaccag
    20221 ctttcaacat tgccaaacca tattcttcca agttcacacc agccaattca gccaattcag
    20281 gagcaatgat tttatctgtt gggtgtgttg ttggtgattt caaaagaagg gtatctgaaa
    20341 tcaaacctga aagcatcaaa cctgcaatct ctttaggcac agctacacca tgttctttga
    20401 acatacggta aacgattgaa gacgctgatc caactggctc caaacgcatg taaagtgggc
    20461 ttgcagtttc aaagttagcc acacggtggt ggtctacaac accgtaaact tctacttcag
    20521 cgatatctga tacagattgt tggaattcat tgtggtcagt caagataact tgctctgccc
    20581 cctctgcttt ggcagaagtg ataacacgtg gtgcttccac accaaaatag ttcaagacaa
    20641 aggctgtttc ttcatttgga gttccaaggg caacagcttc cgtatccaaa ccgtaagctt
    20701 cttttgcaag gtaggcaaaa gctacagatg acccgatggc atctgagtct ggattttggt
    20761 gaccaaatac tagaatcttg gacatgataa tacctcattt tgtttatttt ctttattgta
    20821 gcattttttt cgctttttga caaaggtaag aggagtcaaa ggactcccca cgattcttca
    20881 aaataactga gtaaatttct atcttgattt tcagataaaa attcttcctt ctgtggcctc
    20941 ttcttacgct tgagaagagc ttcagccgac atggcttctt ccttactggc aaaaccttga
    21001 gcatagataa gtttgactgg caagcgtgct cgtgtatatt tggctccctt cccactattg
    21061 tggatagcga ggcgtcttct cacatcagtc gtatagccta tatagtagga tccatcacga
    21121 cactccagaa cgtacatata agccttatga tccataataa atctcttcga tttcgggcgt
    21181 ataagagcca tcatcattgt ggacaatcaa aggaggtaag accttaaagc cacttgttga
    21241 gccatccttg atcgcctcaa tcaaaagcat attggcttcc ttttctcttt ttggataaac
    21301 aaactgcagg cgcttagggg ctagattatg tcgttttaac gtatccaaaa tatccagaag
    21361 tcgatcagga cgatgaacca tggccaaacg cccattagac ttgagaatac tctgggcact
    21421 acgacagatt tcttccaaat tagtcgtgat ttcgtgtcga gccaagagat aatgttcact
    21481 ctcgttcaga ttagaataag gatccacctt gaaatagggt ggattacaca aaatcatatc
    21541 caccttactc ccctgaatgt gagcaggcat atttttcaaa tcatcgcaga tgacctgcat
    21601 ttgttcctct aatccattca aacggacaga gcgttcagcc atatccgcca aacgctcctg
    21661 aatctcaaca gacaatatct gtgcttgagt acgagtgcta gcaaaaagcc ccactgctcc
    21721 attcccagca caaaaatcca caatcaaccc cttcttagga aaacgtggaa atcgtgataa
    21781 gagaacacta tccaccgaat aactaaaaac ctctctattt tgaatgattt tgatatctgt
    21841 cgaaaagagc tggttaatgc gctctcctga ttttaataat tgttcttctt ccatggtcct
    21901 attatagcaa atttatatta acattacaaa aaatataaaa ctctaaacta cttcttcttt
    21961 tttaaatggt gcagggcttc tccagtccag attggtagca ttcgtcgaaa gggagcaaag
    22021 ccgtagttaa agcggtcgct tgaaaagcgt ctccgtctag gaaactggta cttttcttcc
    22081 tccaaagtgc ggatagaaag actggctttc cctgtaaatt catctaaatc cactacctga
    22141 acttgaacct cttcatcgac tttcaaggtt tcatgaatat tttcaataaa tcctgtccga
    22201 atctctgaaa tgtgaatcag ccccgtatca cccgtctcta actcaacaaa ggcaccgtag
    22261 ggctgaatcc ctgtaatacg cccctttagc ttatcaccga ttttcatctt agtcctcgat
    22321 ttcaatagtt tcaattacaa catcttcaac tggcttgtcc atagctcctg tctcaacagc
    22381 agcaatggca tccaagacag cgtaagatgc ttcatcagct aactgaccaa aaatcgtgtg
    22441 acggcggtct aggtgaggtg tcccaccttg attggcatag atttctgcaa tcggttctgg
    22501 ccaaccacca cgagtaattt ctttcttaga ataaggtagg tgttggtttt gcacgataaa
    22561 gaactggctg ccgttggtat ttggaccagc atttgccatg gaaagagcac cacggatatt
    22621 gtaaagctct tctgagaatt catcctcaaa agattcgccg tagattgact ggccacccat
    22681 accagttcca gttgggtctc caccttggat cataaagtcc ttgataatac ggtggaaaat
    22741 gacaccatca tagtagccat cttttgaaag agatacaaag ttagccactg ttttaggagc
    22801 atgttcaggg aaaagcttga tacgtaagtc tccgtgattg gtcttaatag tcgcaagagg
    22861 accttctact gtttcaatgt ctacttgtgg aaaatgcaat tctttttcta ccataccaaa
    22921 tacttctaag gcagcaaaaa tgccatcttc ttctaatgtt tttgtaatat aatctgcttt
    22981 ttctttgatt ttatcatgag aaattcccat ggcaacgctg attccagcat aatcaaagag
    23041 ttccaagtcg ttgagaccat ctccaaaaac catgaccttc tctggtttca agccaaggtg
    23101 ttccacaacc ttttccaccc ccgtcgcttt ggagcctgaa atcggcacaa tatcagacga
    23161 atgttgatgc caacgaacca tgcgaagttt gtctgagaga ctgtcaggca agtgcaagtc
    23221 atctccctta tcttcaaaag tccacatctg atagatatct tctttttcat ggaaatcggg
    23281 atctacatct aagtcgggat aaattggatt gatagcttca ctcatcatat cggtgcgagt
    23341 cgacaacttg gcatcatgac tcccaaccaa gccatactca attccttctt gcttagccca
    23401 agagatatac tcctcaacat ctgacttttc aatctgatgc tgataaatga cctgaccttt
    23461 tttatcttcg atataagccc cattcaaagt tacaaaaaag tcaggcttga gatcacgaat
    23521 ctctggaaca acaccaaaaa tgccacgtcc agaggcgatt cctgttaaaa ttcctttttc
    23581 acgcaactgt ttaaaaacag tggggattgt agttggaata aaccctgtct ttgaattccg
    23641 caatgtatca tcaatatcaa aaaagacaat cttgatcttc tttgccttgt atcttaattt
    23701 cgcgtccatc tcactacctc tttcaatcta actctttcca ttatatcata aagtaggcaa
    23761 atcccctatt ttcaaaaagt ttatcatttt tattttaatt tcttggatga gaaaagagac
    23821 atatttatga aaaagctcca tcgtgctttt aatgtgttct cttgttttca aactcgtaaa
    23881 aagggagcca ctgagcctaa ctcgctctct catttcaaat cttgtgaaaa aagacccgtt
    23941 ggggtcttaa ttcgctttct tgttttcaag ctcatgaaaa agagacccaa tcgggtcttt
    24001 tctttaatct tcgtttacga aaggcatcaa agccattacg cgagcacgtt tgatagctgt
    24061 tgttacttta cgttggtttt tagctgaagt tcctgttaca cgacgaggaa ggattttccc
    24121 acgttctgaa acgaaacggc taagaagctc agtatctttg taatcaacat attcaatttt
    24181 gtttgctgcg atgtaatcaa cttttttacg gcgtttgaat ccgccacgac gttgttgagc
    24241 catgtttttt ctcctttata agtttagttg tccattagaa tggtaaatca tcatcagaaa
    24301 tatccaatgg gtttgttgct ccaaatggat tttcattacg tgaaaagtct ggtactgaat
    24361 ttgtaggtgc tgaatagttt gcagttggtg cagagtaagc tccacctgtg tgaccctcac
    24421 gcacactacg gctttccaac atttggaaat tctcagccac gacctctgtc acgtagacac
    24481 gttgtccttg ctggttatcg taactacgag tctggatacg acctgtcacc ccgataagtg
    24541 agcctttttt agcccagtta gcaagatttt cagcctgttg gcgccacata acgacattga
    24601 taaaatcagc ctcacgttca ccattttgac tcttaaatgt acggtttact gcaagagtaa
    24661 aagtcgcaac tgctacattt gatggggtat aacgcaactc agcgtcacgt gtcatacgcc
    24721 ctacaagtac aacattgtta atcatagttt accttcttac gcgtcaattt tgacgatcat
    24781 gtgacgaaga atgtcagcgt tgatttttga aagacggtca aactctttaa gagctgcatc
    24841 gtcatttgct tcaacgttaa cgatgtggta aagtccttca cggaaatctt ggatttcgta
    24901 tgcaagacga cgtttttccc aagtttttga ttcaacaaca gttgcaccgt tatcagtcaa
    24961 aatagagtca aaacgtgcta ccaaagcgtt tttagcttct tcttcaatgt ttggacgaat
    25021 gatataaaga atttcgtatt tagccattga tatgttcctc cttttggtct aatgacccca
    25081 agactttgca aggggtaagt gaggttcgct cacaataaat tattatacta gaaaaaattt
    25141 ttttacgcaa gtaaaaacac tagaattcga aaaaacgcca catgggcgtt ttcctgttct
    25201 tatggtttga tacggtgcaa catacgtggg aatggaatag cttcacggat atgttttgtt
    25261 cctgctgcaa aggttaccat acgttcgata ccgataccaa atcctccgtg tggaactgta
    25321 ccgtatttac gaaggtcaag gtagaattca tattctgtac gatccatacc aagttcatcc
    25381 atcttagcga caagggcatc gtaatcttcc tcacgcatag acccaccgat aatttctcca
    25441 tagccttctg gagcaagcaa gtctgcacaa agcacgcgct ctggatttcc aggaactggt
    25501 ttcatgtaga aagccttgat ggctgctgga tagttcatga caaatgttgg cacaccaaag
    25561 tggtttgaaa tccaagtttc gtgtggtgac ccaaagtcat caccatgctc aagatgctcg
    25621 tagtcagcat cttcatcatt ttcatgctct tgcaagaggt caatggcttg atcgtaagtg
    25681 atacgtttga atggctctgc aatgtagcgt ttcaagagtt ctgtatcacg ttccaagatt
    25741 tccaaggctt gaggcgcgcg gtcaagaaca ccttgtagaa gagctttcac ataagcttct
    25801 tgcaagtcaa gcgactcatc atgtgtcaag tatgagtact cagcatccat catccagaac
    25861 tcagtcaagt gacggcgtgt ttttgatttt tcagcacgga aaactggacc aaagtcaaag
    25921 acacgaccaa gagccatagc ccctgcttct aggtaaagct gacctgattg gctcaagtag
    25981 gctggcgttc cgaagtagtc agtttcaaag agttctgtag aatcttctgc cgcatttcct
    26041 gaaagaattg ggctgtcaaa cttcataaaa ccgttcttgt caaagaactc ataagttgca
    26101 tagataatag cgttacggat ttgcaacaca gctacttgct tacgagagcg tagccacaag
    26161 tgacggttat ccatcaaaaa gtctgttccg tgttcttttg gtgtgattgg gtagtcttga
    26221 gattcaccga tcacttcgat gtctgtgatg tccaactcat agccaaattt agaacgttcg
    26281 tcctctttga caatacctgt cacataaaca gacgtttctt ggctcaagcg tttgataaca
    26341 tcaaacttct caagtcccac ttcttcacca aatttttcga caaagtttgg tttaaaagcc
    26401 acaccttgaa agaaggctgt tccatcacgc aattgtaaga aagcgatttt tccttttcct
    26461 gatttgttgg caacccaagc gccaatcgtc acttcctgac caacatagtc ttttacgtca
    26521 ataatcgtta cacgttttgt cattattttt ccttttcttt tttattcttt atggcaaacc
    26581 acctctatat tgttcccatc caggtcaatc ataaaagcag catagtaaat cagacgctca
    26641 cttcgataac caggagcccc attgtctcgc ccacctgcct ctaagccagc ctcataacaa
    26701 gcctgaactt cttccttatt ttctgctaaa aaagcaaaat gaacaggatc ttgtgttccc
    26761 tgagtcagcc aaaaatcacc accaggatga gggctgttcg gggatagaaa actaattaga
    26821 gaactagtct taaaagccaa tttatagtcc aaaggagcga gaaaactcct ataaaatcct
    26881 tctgaaattt gtaaatcctt taccttaatc tcaaaatgat caatcattct cactacccat
    26941 aaatgctttc aagcgttcga ctgcttcttt aagcgtgtct aggtctgtcg catagctgag
    27001 gcggacattt tctggtgctc caaatccagc tcctgttacc aaggccactt cggcttcttc
    27061 taagatagca gttgtaaagt ctgtcacatc cgtgtagcct ttcatctcca tggccttttt
    27121 gacatttggg aagagataga aggccccttg cggtttgacc acttcaaatc ctggcacttc
    27181 tgcaaggagg ggatagatgg tattaagacg ttcctcaaag gcctgacgca tgctttctac
    27241 agtatcttgc tcacctgata gagcctcaac tgctgcatat tgtgctactg ctgacggatt
    27301 cgaagttgtt tgacctgcaa tcttggacat ggcagcgata atgtctgctt ctccaacggc
    27361 ataaccaatc cgccaaccag tcatggcata ggttttagac acaccattga tgaccactgt
    27421 ttgcttgcga atcgcttccg ataggctaga aatcggtgtg aactcatgac cattataaac
    27481 caagcggcca tagatatcgt ctgctaggat gagaatatca ttttctacag cccagtttcc
    27541 aattgccaag agttcctcac gggtgtaaat catacctgtg ggattagatg gcgaattcag
    27601 caccaaaacc ttggtcttgt cagtgcgagc tgcttctaac tgctctacgg tcaccttaaa
    27661 gtgattgtct tccttagcag aaacaaagac gggaacgcct tctgccatct tgacctgatc
    27721 tccatagcta acccagtatg gggttgggat gatgacttca tcacctggat tgaccacagc
    27781 cataaagaag gtatagagag aatatttggc tcccgcagcg actgtcactt gatttgatgc
    27841 tacagaatag ccgtaaaagc gctcaaagta gctattgacc gcctccttaa gctctggcag
    27901 acctgaggtt actgtataaa aagaagcacg cccatctcga atcgatgcaa tggcggcatc
    27961 ttggatattt ttgggagtag tgaaatctgg ctcacccaag gttagagaca aaatatctct
    28021 actctcagcc ttcagtgctt tggcacgggc tccagcagcc aaagtcacac tttcttccat
    28081 ttctaaaaca cggttggata gtttcatagg ccctccttgt tgaccaatgc tcctgtttca
    28141 aaatctacta gataaaaatc agatcctgac ttaacttccc agattggctt atcttgataa
    28201 cggccaaagg ttatcttgtc aatctcgcca gctccctttt ccttagaaac cgtttctgct
    28261 ttttcttgtg aaacaccctg atttagctga taaacgtaaa tcttatggtc atctttacca
    28321 atcaggacag caagcgcttc ttgctgttta ttacgaccaa gaacgctgta ataagattcc
    28381 aagccattgt ataaatcaac ctgatcgacc tgctctaatc ctgcatactg ctgagctaat
    28441 ttttctcctt cacttttagc tgtttgatag ggtttcatgc taagagaaac catatacaga
    28501 aaggaagcac tgataaccac aaacaaaatc gtcatcccta gaccatactg ccacagtaga
    28561 ttattttttg ctttgttttg tctttttttc actcgtctat tttaccatct attaagcttt
    28621 attacaagtg aatataagaa tactcttcga aaatctcttc aaaccacgtc agctttatct
    28681 gcaacctcaa agctgtgctt tgagcaacca attctatttc tcccttcaaa caaaaccgat
    28741 tttgaaagtg aaacagttct tactttttca gtcacaaatg attagagttt ccgaaatttt
    28801 acaattttca aataaactct gagcaaattt cttgcaagtt cttttgtttt gttgtaatat
    28861 attttataac aacgagagag ttctcgaaat tttaagaaaa aggagacaca tcatgtctaa
    28921 aaaagtatta tttatcgtcg gatcactacg tcaaggttct ttcaaccacc aaatggcgct
    28981 cgaagctgag aaagcacttg ctggtaaagc ggaagttagc taccttgatt attcagccct
    29041 tcctctcttc agccaagatt tggaagttcc aacacatcca gctgtagctg ctgctcgtga
    29101 agcagttctc gttgcggatg ctatctggat tttctctcca gtctacaact tctctatccc
    29161 tggtacagtg aaaaacttgc ttgactggct atctcgtgcc cttgacttgt ctgatacacg
    29221 tggcgtttct gcccttcaag acaagtttgt cacagtatca tctgtagcca atgcagggca
    29281 cgatcaactt ttcgctatct acaaagacct cttgccattt atccgtacac aaggcgttgg
    29341 tgatttcact gctgcacgtg ttaatgactc tgcctgggca gacggaaaat tggttcttga
    29401 agaaacagtc ctaaactcac ttgaaaaaca agctcaagac ttggtcgaag ctatcaagta
    29461 actaacactc aataaaaatc aaaaagcaaa ctaggaagct agccacaagc tgctcaaagc
    29521 actgctttga ggttgtagat agaactgacg aagtcagtga catatatacg gtaaggcgac
    29581 gctgacgtgg cttgaagaga ttttcgaaga gtataacata ataaaagcga acaagactac
    29641 ttttctgaca ctcagaagac tagcttgttc gctttttttc tcatttataa actaaaacag
    29701 ctgatgatac atattgccaa atacaaaata tctgatttct atacttcctt tacaaaaacc
    29761 aatccctgtg gttgtgacaa atcttctcga taaacaaatc cagcaaagtt caagcgacgt
    29821 gcttccccca cagtttgtac ttgattttct attaaagctg ttagaaaggc cccgcgcgct
    29881 ttcttggaga tagttgagtg aatcttcagc tgaccgcctc tatcctccat gaatttgaag
    29941 gtcaccatct ttgctctgat ttccttagaa aatacagtct caaactctga tgacaagaga
    30001 gagaaaatca cttcttcctt cttcagagct tcatcataga ctgctttcca atggctcttc
    30061 aaagtcttac cagcgacttt taatttcatc aaaaaatcca aacggtgagg agccatgagt
    30121 gacaaggctg gaacaacacc gtacaaagcc gaggtaatga agacatgatt ttcaagataa
    30181 tcttgttccg cctcggtcag cttatctctc ttaatgttgc ggtacataag cccatcaaaa
    30241 agtttcaagg ctggatagtg ttgagcagtt tgccttttca aagcttggat attttgaaat
    30301 tcttccgccg ctttctcagc tgataccttg tagaaactct ccaattgact ggcagaatag
    30361 agagccaagg catcaagcac ggcctgactt tctggtttta aaggaattgc ctcgatactt
    30421 ggcaagtctg tgttcatttc ttttgctgtt gggattaaaa ttttcatatt gatagtgtag
    30481 catatttttt agccacaacc aagaaattca tttgaaaaac ctcggtttga ccgaggtttt
    30541 tctatttatt tgggccatcc taaccagaca gccacgagaa caagggctgt gccagctaaa
    30601 cttgttaaga tagataagaa tttatctttt ttctccttga actgagaaaa acctatcttc
    30661 aaagcgagca gtccgagtag cattgaagca accatcaaat aaaaacccat ttctttgtcc
    30721 tccattaggc ttaatttacc ttattataac atatatttct taaataaacc ttttttatac
    30781 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgctcaaa acactgtttt
    30841 gaggttgcag atagagctga cgtagtttga agagattttc gaagagtatt attgtacttt
    30901 aaaggtcttg agatagttgt cttttcctac ttgaccttcg aaggttttac cattttcaag
    30961 gtaaggaagg tcatcggata ctgaagcctt taccttgtat atcttgctat caactttaaa
    31021 gaagtagaca gtgtctccct tgataacagc tgatttgagg tctgctacta ctcccttgat
    31081 gctttctgtc gttgcattgt caatttcaag gtcgttttta ttggcatact tgctgagcat
    31141 ctcttccact gtagtagcaa cgataacatt ttggtactcg actgcgtcta ccagggcgta
    31201 ctctttgacc aagccagcat tgtcctttaa gcccatgatg tagagaggct tgtcattgag
    31261 gttgatgagg attgggaagg ttgctttgta ggatttctcc tgaacagcac cttctgctga
    31321 ttcacgggct gattcttctg tcgcagaagc caagctatac ttagtaattt ctcctgttcg
    31381 catattttca aggatgaaac caagattact ctcatccgca ttagccgacg tcacacctgt
    31441 gtagagatag atgtcattac cgatagacaa gtaattatag ccattggtag tctgggtcac
    31501 gtttttcttg gaaatcatgg cattcaagaa accgtccttg tacttgccgt tgtagttgat
    31561 ttgctcaatg gtttcctctg ctggatagat cctgtccacc cattctggaa catctgataa
    31621 gctgtattcc ttggtttctc catttgtagc atccaagata atgactgaag caggacgagg
    31681 aacagcaagt ccaaattgct tttggtaaac cgttgctaca tagaaaggat tgccctcatc
    31741 gtccacctca aaagatggag ttttaaagat tttggtcggg tacttcaagc gcaggtgacg
    31801 tttgacatca cggttaaaat actccgagtc tgaatacttg attggtgtct tcaagtccac
    31861 caaatccgca tttccagtta ccatgtccac cttgatatac tcaccgattc ccttggcttg
    31921 attgttaaac catttgatag ggtctgcata ttctagtggt gtgacccgat aaggtttccc
    31981 atcaattgtc aattgggtat aggtatctgc cgctacgtat tgcgacacct tatcggttag
    32041 ggaacccaag tagcggtctc caattttttc agcagtactt ctatctagga taggaacctt
    32101 actggtgtca ctcttaggaa attcagtaaa gtctttttcc gtaaccgtga ctacattggc
    32161 ataattttta gcctgaaaca tgctggaagt taccaaggaa accaaagctg ccaagagaag
    32221 aattcctcca atcgaagcta acagaatttt ccctaaccga ttgattttga aaccctcaag
    32281 atttaaggca gcttccgcct taccgtggcg cacatgaacc gttttgacaa ggtttatccc
    32341 cttgccaaag ccaaataata ttgccacaac taacaaatgc ccacagagga agaagagaaa
    32401 ttcccagctg gtcaggttaa ggggcggtaa aaagatatac caggtcgttg cgataaaaat
    32461 aagttcaaag actattcgtt tcatttgctt tcctcctaaa tgattcgtcc ttccaagtga
    32521 tccagctcat gctggcaaat ctgagctggg aagcctgtca aggtaatggt ctgttcctgc
    32581 cacttgctgt cacgataggc aagccttatg gtttcataac gcttagttga tctcacacct
    32641 accaaggaca aacagccttc ttctgcctca taggatcctt caaaggacag aagcactggg
    32701 ttaaacatga ccacgggaac caagccaaga ttaaagataa tcacgcgctt ctgcacccca
    32761 atcatattgg cagctagacc aacacaggta tcacgatttg ctaagagtgt atcctgcaaa
    32821 tctctggcaa gataaaggtc ctcctgactt gccggcttag acacttgaga taaaaataag
    32881 atatccttca caattttctt ttccacttcc tcacactcct cttgcttttt actatattat
    32941 agcaattata gcacaaaagc cgataactgc aaaccctttc cctcaactgt agcaaaaagc
    33001 catccgaaga tgactttttt gctatttaat ttctgtataa gttacttcca agccacgctt
    33061 aacagctgga cgattggcaa ttttttctgc ccattttact agattttgat aacttgaggc
    33121 atccaagaat tttgcagaac cttggtaaag atttccttga actaactgtc cataccaaga
    33181 ccagatagca atatctgcaa tcgtatagtc attgcctgca atataaggtt tctgagccaa
    33241 ttccttatcc aataaatcca actggcgttt cacttccatc gtaaaacggt taataggata
    33301 ttccaatttt tcaggagcat aattgaagaa atgtccaaat cccccaccta gaaaaggtgc
    33361 tgcacctgct tgccagaata gccaattcaa aacttctacc ttttccacag gattacttgg
    33421 taaaaaggct ccaaatttct cagcaaggta aagaagaata tgagcagact caaagactct
    33481 tacgttttca gtacctgact ggtccaataa ggctggaatc ttggaatttg gattgagctt
    33541 cacaaagtct gagccgaatt gatccccatc catgatagca atcttataca agtcgtaagc
    33601 cgcttcctta aaaccagctt ctagtaattc ttccaataag atagtaacct tcacaccatt
    33661 tggtgttccc agtgaataaa gctgaaaagc ttgttctcct tttggcaagt tttgttcgaa
    33721 acgggcacct gctgttggtc tgtttagccc cgtaaaagct ccttgattac tagcttcatc
    33781 ctgccataca gtcggtaatt gatatgctga catccgaaac ctcccttaaa tcgcattctt
    33841 gtcaaaaccg agtttgcgtt gaataaactt aacgatttcg acgatgataa tcattgagaa
    33901 gcttccagcc ataacaattc cccattgtga caagtctagt ttggttacgt ggaagattcc
    33961 ttcaagcggt tctacaacga ttgttgccat gagaaggata aaggatacca agatggacca
    34021 gttaaaggtc ttagacttga atgggccaac tgtcaagatg gattggtaga cagacttgac
    34081 attgtaggca tggaagagct gaatcaaacc aagggttgca aaggccatcg ttagggcatc
    34141 tgcatgaata gcatgattgt cacccacatg aactgggtaa gcaatcgcaa ggccataaac
    34201 actcataaca agagctgctt ggagtacacc ttgataaatg atagaactca aaacaccacc
    34261 tgagaagaag cttgccttgc gtccacgtgg tttatgattc atgacaccag gctccgcagg
    34321 ttcaacacca agagcgatag ctgggaaggt atccgttacc aagttgatcc acaaaagatg
    34381 aaccggctgc aagacatccc aaccaaacaa ggttgatagg aagatggtta atacttcagc
    34441 agtattagca gaaagtaggt actgaatagt cttttgaatg tttgagaaga ccttacgtcc
    34501 ttcttccact gcgacgataa tagtcgcaaa gttatcatct gcaagaatca tgtcagaagc
    34561 ccccttagaa acttctgtac cagtgattcc cataccgata ccgatatcgg ctgttttcag
    34621 agctggcgcg tcattgacac catcacctgt catggcaacg actttacctt gtttttgcca
    34681 agccttgacg atacgaacct tgtgttctgg agacacacgg gcataaacag agtattgacc
    34741 aacgactttt tcaaattctt catctgacag ttcattgagt tcagcaccag ttaaaacgtg
    34801 accttctgta tcgtttgcgt caatgattcc caaacgtttg gcaatggctt ccgctgtgtc
    34861 ttggtggtca cctgtaatca taattggacg gattcccgct tccttagcca cacgaacagc
    34921 ctcagcggct tcaggacgtt cagggtcaat catcccaatc aaaccagtaa aaattaaatc
    34981 attttcaagc tcttcagaag tgagattttc tggaatacta tcgataatct tataagcacc
    35041 tgcaaggaca cgcaaggctt gatgagccat ttcagaattg tttgtatgaa tgagatttgt
    35101 aaccttctca tcaatcggag caatatcccc agccttatca cgaagaagac aacgctttaa
    35161 gagttggtct ggcgcaccct tgactgctac aaggaaacga ccatctggca atgggtgaac
    35221 tgttgacatg agcttacggt cagagtcaaa tggcaattca gctacacgag gatatttctc
    35281 taagaaacct ttgacatcat agcccttgtc caaggcatat tggataaagg ctgtttcggt
    35341 tgggtcacca atcaagttac cttccacatc gattttcgta tcattggcca agacaactga
    35401 acgaagtagt ggcatttcaa gacctagttc aatatcatca gctgagtcat gtagaaccgc
    35461 atcgtagaag actttttcga ctgtcatctt gttcatagtc agcgtaccag tcttatcaga
    35521 agcgatgatt tcagttgaac caagtgtttc aactgctggc aacttacgaa cgatggaatg
    35581 tcgtttggcc aaaacttgag taccaagaga aagaacgatg gtaacgatag caggaagtcc
    35641 ttctggaatg gctgcaacgg caagggcaac agaagtcaac aactcaccaa gtggattttt
    35701 cccttgaatg aagacaccca ctacaaaagt aacaagggca atgaccaaga tagcataggt
    35761 caagacctta gaaaggttgt tcaagttttg tttgagtggt gtatcagtct catccgcatc
    35821 ttgaagcata ccagcaatat gaccaacttc agtatacata cctgtattga caacaacacc
    35881 catcccacga ccataggtta cgtttgagtt ttggaaggcc atgttgacac ggtcaccaat
    35941 accagcatct gtcgcaagct cgactgacaa gtctttttcg actggtacag attcacctgt
    36001 caaggctgct tcttcaattt taagagagtt ggcttctagc aaacgtaggt ccgctggtac
    36061 cacgtcacct gcttcaaggg caacgatatc gcctggtacc aattctttag agtcaatctc
    36121 tgccatgtgt ccatcacgaa gaacgcgggc aactggacta gacatggatt tgagggcttc
    36181 gatagcttct tcagcttttc cttcttggta aacaccaaag gcagcgttga tgataaccac
    36241 agctaggatg ataatggcat ctgcgatatc ttccccacca gaagtcacga ctgacaagat
    36301 tgctgccgca actaggatga taatcatcaa atccttaaat tgctcgatga atttgaccaa
    36361 gattgatcgt ttctcgcctt cttcgagttc attgtgccca aattcggcaa ggcgcttttc
    36421 cgcctcactt gatgacaaac cttgctcggt cgcatccaca gcctgcaaga cctcttcagg
    36481 gctctgagta taaaacgctt ggcgtttttg ttcttttgac atgtgtctcc tccttgacat
    36541 tgtgtgcaaa acagactctc tttctgtcat atcttttcac gacaaacaaa aagagacctg
    36601 ttaatcataa caagtctcgc tgtttaagat agggccggaa agcatacttt tcagcataaa
    36661 attcggaatg acgacactat cacaggtttc tgccagctac tcccttgagt agtactatta
    36721 taccaaattt tggggagttt tcaaagagta aaaactacct tatttgaatt tttccttgaa
    36781 aaccagtata atggtagaat gctatgtgac tagaaaggaa gttgaatgaa gcaatctatc
    36841 tcaaatctca agttagctga gcgtggagct attatcagta tttcgaccta tttgatcttg
    36901 tctgcagcca aattagcagc tggtcatctc cttcattcat ccagtttggt ggccgatggt
    36961 tttaataacg tatcggacat cattggaaat gtggccctct taatcgggat tcggatggcg
    37021 cgccagcctg cagaccgtga ccaccgtttt ggtcattgga agattgaaga tttggcaagc
    37081 ttgatcactt ctatcatcat gttctatgtc ggtttcgatg ttctaagaga taccattcaa
    37141 aagattctca gtcgggaaga aacggtcatt gatcctcttg gtgcaactct aggaatcatt
    37201 tctgcagcga ttatgtttgt ggtctatctc tacaatactc gcctcagtaa gaaatccaac
    37261 tccaaggcgc tgaaggcagc tgctaaggac aatctttctg acgctgttac ctcacttgga
    37321 accgccattg ccatcctagc tagtagtttc aattatccga ttgtggataa actggttgct
    37381 atcatcatca ctttctttat cttgaagact gcctatgata tcttcatcga gtcttccttt
    37441 agtctttcag atggctttga cgaccgcctg ctcgaggact accaaaaggc tatcatggaa
    37501 attcctaaaa tcagcaaggt caaatcgcaa agaggtcgca cctacggtag caacatctac
    37561 ctggatatta cactagagat gaatcctgac ttgtctgttt ttgaaagcca tgaaatcgcg
    37621 gatcaggtcg agtctatgct ggaggatcgt tttggcgtct ttgataccga tgtccatatc
    37681 gaaccagcac ctatccctga ggatgaaatt ttagacaatg tctataaaaa attgcttatg
    37741 cgtgaacaat tgattgacca aggaaaccaa ctagaagaac tcttgactga tgattttgtc
    37801 tatattcgcc aagatggaga gcagatggat aaagaggctt ataagaccaa aaaagagtta
    37861 aattctgcta tcaaggacat tcaaattact tccatcagtc aaaaaaccaa actcatctgc
    37921 tatgagttag atggtatcat ccataccagt atctggcgtc gccacgaaac ctggcaaaat
    37981 atctttcatc aagaaaccaa aaaagaatag agaaatcctt tcatgagacg ggatttttct
    38041 attcttttat actcaataaa aatcaaagtg caaattagga agccggtcac aggctgtact
    38101 tgagtcggca atgtgaagcc gacatagttt gcactttgat tttcgaatag tcttaactat
    38161 caaattcact gagatactca tagcgttcgt atttttcaag gagtgcttca tttttctcat
    38221 ccaattcttt ttggagagta gccagcttac caaagtcaga gccgttagcc tgcatttcct
    38281 cttcaatagc agcgatacgt ttttccaagg tttcaatatc accttcaata cttgcccact
    38341 cctgcttttc ttggtaggtc atgcgtttct tgtcttctcg aaccttgacc actttttcct
    38401 tttcggcctt ttgcacttga ttggccatat ctgtttcaaa agctttttca tcaagatagt
    38461 cggtgtaatg accaaagaaa ggacgaatct tgccatcctc aaaagcgaga atcttggtcg
    38521 ctaccttatc caagaaatag cggtcgtgac tgactgttaa aacgggacct gcaaaacctt
    38581 gcaagaaatt ctccaagact gtcaaagttg caatatccaa gtcattggtt ggctcgtcta
    38641 aaagaagaac atttggtttt tccaagagca gtttgaggag ataaagacgt tttttctcac
    38701 caccagataa tttctcaatc aaggttccat gcgtcgaacg tgggaaaagg aactgctcca
    38761 gcaactctgc aatcgaagtc gtagaaccgc cactggtctt gacctcctct gccacttcct
    38821 gcaggtaatt gataactctc ttgctttcat ccaaaccctc aatttgctga gagaaatagg
    38881 cgatgcgaac agtttcccca atcacaactt gtcctttagt tgactcaaga cttcctgcaa
    38941 ttaagttgag taaggttgat tttccaacac cattgtcccc aacaattcca atacggtctt
    39001 tagcctgaac taagagatta aaattttgca aaatgggctt attttcatag gcaaaggaaa
    39061 catcctgaaa ctcgatgact ttcttcccaa tccgactggt ttcaaagttc atagtcaagt
    39121 ctgtctcagc actactgcct gaaacttcct ttttcagatc atggaaacga ttgatacgag
    39181 cttgttgctt ggtcgcacgt gcctgcggtt gtctgcgcat ccaggccagt tcttgtttgt
    39241 agagttgttc ttttttatga agtagagctg catcgcgctc gtcctgttct gccttaaggc
    39301 gaacatagtc ctggtaattg ccctgatatt ctgtcaagcc tgctcgctcc aactcgaaaa
    39361 tccgtgttga caaagcgtct aagaaataac gatcgtgagt gataaaaagg acggtcttct
    39421 tagaattttt caaaaagagg gtcagccact caataatcgc aatatccaga tggttggtcg
    39481 gctcatccaa aagcaaaagg tcgtggttgc caagtaagac ttgtgccaac tgtacccgtc
    39541 ttctcagacc acctgacaat tccccaacag gagtagataa gtcttgaatg cccaatttgc
    39601 taagaacggt cttgacctga ctttcgattt cccaagcttg gagagagtcc atctctgcca
    39661 tgacacgttc caaacgcgcc tgcttgtcct cactatagtc gagcataatc aattcatact
    39721 cacgaatgag ctggatttcc ttgagttcac tagatagaac cgtatccaaa actgtctttc
    39781 tatcatcaaa atcaggatcc tgagtcaagt aaccaatctg gtaatcattt ttagctgaaa
    39841 aaggactgac atccccatca aatccagaaa caccagaaag gacgtccaaa agggtggtct
    39901 tgccagtccc attgacaccg attaaaccaa ttctgtctaa gtcatggata ataaaggaaa
    39961 tatccctaaa aacggtcttg tcaccaacgg atttacttag tttttcaacg ataaaatcac
    40021 tcattttttc tccctcaggt aagcatggat ggcttcacga ttattctcca attctccatc
    40081 gacaatggca aactcaatct ctgttaaaat ctctcccaag tctgggcctg gctgatagcc
    40141 atattccttg atcaaaatac cgccattaat ctgaatatct ttcttgtcat ggatagtcaa
    40201 gctttggtat ttttctgtga tggcttgtgg gttgacttct tttccttgag cttgacgaag
    40261 attttcagcc tgtaaaagca aatctatgtc aaagcgataa caatctcgct tgctcaattc
    40321 tccattttca cgcagagcca aaataatcag caaatcctga acttgcttgg caaactggcg
    40381 tgaggtcttc caagatttca aaaatgactg cgcattttca atctccaaag cccatagtaa
    40441 agccgcccag gcttgttcag aggattcaaa agtaaaatca gtctccaaat caaacagtct
    40501 gttgagcttg tcctggctag atgccatatc agggagatag tcataagctt gactctcaat
    40561 catggaagcc aagccccttc tccaaaatgg agccagcaag agtttatcaa actcgacgaa
    40621 ggtacgctct acagaaattt tctccaaaag cggcgtcaag gtcttcatag ctttaaatgt
    40681 ttctggctca agtgcaaaac caagactagc ctgaaaacgg aaaccacgca taatccgtaa
    40741 agcatcttcg ttgaaacgct cactagccac tccaactgct cgcaagactt gcttttccaa
    40801 atcttctaaa ccatggaaca agtcaacgat ttctcctgtc tcatccaagg caaaggcgtt
    40861 gactgtgaaa tcacggcgtt tgaggtcttc ttctagcgag cgcacaaagg aaaccgcact
    40921 gggtctgcga tagtccacat agacatcctc tgtccgaaag gttgttacct catactcctc
    40981 atccccatct aagaccaaga cggttccatg ctcgattccg atatcggctg ttcgcggaaa
    41041 aatctgcttg gtctcttctg gataagaaga cgtcgcaata tccacatcgt ggatagggct
    41101 atggagaagg gcatctcgaa cagagccccc aacaaaataa gcctcaaagc ctgcttcttt
    41161 aattttttct aatactggta aagccttctg aaattcagaa ggcatttgcg ttaatctcat
    41221 aataagtgtt ctaatccata gacaagctca tgacgcttga caacttcttt aattcccaaa
    41281 ttgactcctg tcatgaagga gatgcgatca taggagtcat gacggagggt caacccttct
    41341 ccctgattgc caaagatgac ttcttgatga gctaccaagc ctggcaaacg aactgagtgg
    41401 atgcgcatac catcaaagtc agcaccacga gcaccagcaa tcagctcttc ctcatctgct
    41461 gcgccttgct gaatggactc tcgaacctct gccatcaact cagctgtttt aatggctgtt
    41521 ccactcggag catccttttt cttgtcatga tggagctcaa taatctccac atttgggaaa
    41581 tatttggcag cctgcgtcgc aaattgcatg agtaagacag cacccaaggc aaagttaggg
    41641 gcaatcaggc cacccaagtc ttgggcacga gaaaattctt ttagctctgc aatttcttca
    41701 ctcgtgaaac cagtcgttcc aactactgga gcaaagccat tttcaagagc aaaacgtgta
    41761 ttttcgtagg caacagctgg agtagtaaag tctacccaga catccgcttc aaaaccagct
    41821 aaatcagcct tatccttgaa aacaggaata ccctgccatt ctgactcaga ctcaaaagga
    41881 tccaaaactg ctaccaagtc caaatctgaa tcagtcaaga ccatctggca agcagcttga
    41941 cccatctttc ccttaaaacc ggcaataatt actcgaatac tcatctctac tcctgtctaa
    42001 gatacaaagc ctgtaagaac acaaagtgaa aataggaatt ctgatcaaga agtgtctact
    42061 ccttggaaga actatctttt tcacacaggg ttccaggcgt gttcaattat caagatacaa
    42121 aggatcttag ccacccatga aaaataggga atggcactga ctttccacga aaggcaagac
    42181 agacatcttt tttcaagagg caggtagtcc gtgttcaatt gctaagatta actagcctag
    42241 aagtgcctac taaatcactg gaatataacc cagagcaata cttcctgctc ctaggtgcgt
    42301 tccaatgaca ctaccaaatg tagcaagtga aacatccgaa cccaagccaa aatcaagcaa
    42361 atgctgacgc aattcttcag ccttttcagg agcattccca tgaatgacaa tgacccggta
    42421 ttgacctgaa gccgttgttt ccttgataat ttcaattaag cgtttggtgg ccttcttttc
    42481 agtacgaact ttttcgtaaa cttcaatcac accttgatcg ttaaaataaa ggattggctt
    42541 aatgctaagc aaattgccca aaatggcagc cccatttgaa aggcgtccac cttttaccaa
    42601 atgatccaag tcatctacca tgataaaggc tgacgtacgg ctgatttgaa tggctagctt
    42661 atcctgaatg ctggcaaaat catcgccctg atcacgccaa ttaaagacgc tttcaaccat
    42721 gatgcctagg ggagcacttg taatcaaagt gtctgggaaa gcaatggtta agccctcata
    42781 gtcatcgacc atatactgga tattttggta aaaacctgaa attccagaag ataggaaaag
    42841 ccccaaggca tgtgtatagc cttgttcttt gagcgaagtt aagatttcat ctaacttggc
    42901 aatacttggt tgactggtct taggcaattc agaagcctga gccatttttg ggtaaaattc
    42961 ctcagcagac agattgatgc cttcgacata ttcctcacca tcaatattga caggaatatc
    43021 caagacaaac aagtcttctc tttgcaagat ctctgcactg agataagcag aggaatctgt
    43081 gaaaacagct aatttcatat tagaactcca aattaattcc tggtaagtct aatgcaattt
    43141 cagtcacttc gtaagtcaaa cgattgagca tgttcaaaca tggacgagcc aaggtttcca
    43201 cctcttcttg gttcaattca cttggttcat tgacaatacg gccatcgata tggtttactt
    43261 gtgagattgt tccactaatg acaaacttat caaatacaat cataaagctc aagatgacaa
    43321 tcaaggaagt cacttgattt tcttggtcat gttggagcaa ttggaaattc acatccacct
    43381 tggtttcagg agctccattt tcattttccc attcaaaatt acgcgcatca aaatgatact
    43441 gactaacaaa ttcttgttca cgtttaagat tcatgtcttt ctccatcagc tacaatatta
    43501 taagctattg taccataatt ttttattttc atctagtttt ctaggattta gtcaatccca
    43561 atttcagcac gaactacatc tgtgatggta tcaacatagt agtctacttc ttctgttgta
    43621 ggcgcttctg ccataacacg caagaggggt tctgttccac ttggacgaac aaggatacgg
    43681 ccgttccccg ccatttcttc ttccatcttc tcgatgatgg ccttgatagc tggcacttcc
    43741 atggcctttt ccttcatgac gttttccact cggatattaa ctaatttttg tggataaatc
    43801 gttacttctg ccgccaactc tgataagctc ttaccagttt ccttcatgat tttagtcaat
    43861 tgaactgctg ataattgacc atcacctgtg gtattgtaat ccatcaagat aacgtgacca
    43921 gactgttcac caccaaggtt gtaacctgat tttctcattt cttcaacaac gtagcggtca
    43981 ccaactgcag taactgcctt gttaatacct tcgcgattca aggccttgtg gaaaccaagg
    44041 ttagacataa cagttgtcac aattgtattt tgagccaatt gtcctttttc agaaaggtat
    44101 tttccgatga tgtacataat cttgtcacca tcgacgatgt caccattctc atcaacagca
    44161 atcaagcggt cactgtctcc atcaaaggcc aaaccaatag ctgacccact ttctttgacc
    44221 acttcttgaa gggcttctgg atgtgttgaa ccaacattaa ggttgatgtt aagaccgtct
    44281 ggtgtttccc cgataaccgt caattgggca ccaaggtctg caaagatttg acgggcactg
    44341 gtagaagctg ctccattagc tgtatccaag gcaaccttca ttccatcaag aggagttcca
    44401 gttgaaacaa ggtatccttc atacttacgc aagccttctg gataatctac caaaattcct
    44461 aagccttctg cacttggacg aggaagagtg tcttcctcag catctagcaa ggcttcaatt
    44521 tctgcttctt tttcatcatc tagtttgaag ccatcaccac caaagaactt gattccgtta
    44581 tcaagggctg ggttgtggct agcagaaatc atgacaccgg cacttgctcc ttcagtttca
    44641 accaagtaag ctactgctgg tgttgcaagg acaccaagtt tgtatacgtg aatccctact
    44701 gaaaggagac ctgccaccaa ggccgattcc agcatttccc ctgaaatacg tgtgtcacgt
    44761 cctacaaaga ctttcggcgc ttccgtttca tgttgactaa gaacatagcc tccaaaacgt
    44821 cctagtttaa aggctaattc tggtgttagt tctaggttag cttctccacg gactccatca
    44881 gtcccaaaat atttacccat tgttataaaa tccttttcta tttttaattc gtttttgaac
    44941 tagttgcttt cgttgacgaa gatgtctccg atgaactgct tgtacttgaa tttgatgtgc
    45001 ttgaacttgg tgctactggt tttgtagtca ccttcattat tgtatcaaac ggagtgataa
    45061 ctgccggtaa gacaacacca ttgcggtcga ttgcctgcaa aggtactgaa ccactgtaat
    45121 tacctgttat gcgttcgcta gttggcaaga cagcgataat cttatcaatt ctatccaatg
    45181 tctcttggtc actcgtaata gacacttctt tatctgacac catgacattt tcaatttgta
    45241 cccgactatc aatttgacta gggtcaatct ctggtacaat ctttacctta tccttctgag
    45301 ccttcttacc aatcttgact gtaatttttt gcggagtcgc cacagcggtc agcccattgg
    45361 gtaaatcttc aatgctcaaa ggaatttcaa tcgttccaac accggcatct gttaggtcag
    45421 cagtaacctt gaatttacgt gtactttctt gcatttcact agctagcgat aggcgatttg
    45481 caccagtcaa gaccactgat acttctgaag caaaaccgct aataaaatac ttatcactat
    45541 tatagcgtat gtcaataggg acatttgtta ctgtattagt ataggtttcc gtttttacct
    45601 gcctagcact ggtactgttt tgaaaattcg tcgccgtagc atagacaaat aagacacaag
    45661 caaaaaagag tgaggatatg atatataaac tatttttttt catgtttcca tcctcctagc
    45721 aatcgttctt taaaactaag acccacttcc tcttttggaa gtaagatttc acgtaattct
    45781 gtttcaaatt catcaagtgt taggttgtgc ttaaaccttc cattataggt tatcgaaatt
    45841 cctcccgttt cctctgatac gacaaaagtc aaggcatctg agacttctga taaaccgata
    45901 gccgcccggt gtctggtccc aaattccttg gaaatccctg tgttttttgt caagggcaga
    45961 taggcagacg tcacagcgat acgttcttct ttgataatca ccgcaccatc atgtagggga
    46021 gtgttgggaa taaaaatgtt aatgagaagt tctgcagaaa tcttagcatc caagggaatt
    46081 cctgtcgaaa tatactcctg caaggtacgt acacgctgaa tagcaaccaa ggccccgatt
    46141 ttacgaggac tcatgtattc aacagactta acaaaggcac gaatcatctg ttcctcagca
    46201 ctaatagggg cattggaaaa gaaatctgtc gctcttccca aacgttccaa accagtccga
    46261 atctctggag agaagataac aaccgccgca ataaccccat aagtaataat ttgattgatt
    46321 aaccaagaaa tcgtagtcaa accaatcata tttgcaagga tttgagctaa aataaacacc
    46381 aaaactccac gtaccaaaat cataatcttg gttcctgcaa tagcttttgt aaaatggtat
    46441 aaaatataag caacaatcaa aatatcaatc agattgatag ctatcgtcca tggacttgca
    46501 aacaaactgg tccaatattg cagattggat aattgttgaa aattcatccc tgatatcctc
    46561 cctatcaaaa cactttcgtc ctattatacc attttctggc atttttttcc ctatcctagt
    46621 ccattttaca ttgaacaaaa atatgataaa ataaactgac tagaaaaaac aaaggagaaa
    46681 ctatgtctca actctatgat attaccattg tgggtggtgg tcctgtcggg ctttttgcag
    46741 ccttttatgc ccacctacgc caagccaagg ttcaaatcat cgactctctt ccccagctag
    46801 gtggacaacc tgctattctc taccctgaaa aggaaatcct agacgtacca ggcttcccaa
    46861 acctgactgg agaagagttg actaaccgct tgattgaaca gctaaatgga tttgataccc
    46921 ctattcatct caatgaaacg gttcttgaga ttgacaaaca agaagaagaa tttgccatca
    46981 caacttctaa aggaagtcac ctgactaaaa cagttatcat cgctatgggt ggcggtgcct
    47041 tcaaaccacg tccgctggaa cttgaagggg ttgagggcta tgaaaatatc cactaccacg
    47101 tttctaacat tcagcaatac gctggtaaga aagtgacgat tcttggtggg ggagactcgg
    47161 ctgtggattg ggctttggct tttgaaaaaa tcgcaccaac tacccttgtt caccgcagag
    47221 ataatttccg tgccttggaa cacagtgttc aagccttgca agaatcatct gtaaccatca
    47281 agacaccatt cgcccctagc caactccttg gaaatggaaa aacacttgat aaacttgaaa
    47341 tcacaaaagt caaatctgat gaaactgaaa ccattgacct agaccacctc tttgtcaact
    47401 atggtttcaa atcttctgtc ggtaacctta aaaactgggg gctcgacctc aaccgtcaca
    47461 agattatcgt caacagcaaa caggaatcca gccaagcagg tatctatgct atcggtgact
    47521 gctgctacta tgacggaaaa attgatctga ttgcgacagg cctcggagaa gctccaactg
    47581 ctgtcaacaa cgctatcaac tacattgacc ctgaacaaaa agtacaacca aaacactcta
    47641 ctagtttata aaaaagaacc acgagtcaca taggattcgt ggttttataa ttcatccgct
    47701 atcttattga tttttctgag tctgtgattg acaccacttt tggtcagagg ggtgctgaga
    47761 ctatctgcta actgctggat agagtagtct gggtgctgaa tcctcagttg cgccacttcc
    47821 tgcaaatcta ctggcaaatt ttctaagccc atgatatctt tgattttact gatattgtta
    47881 atggtcttca tgctggcaga aactgtccga gcgatattag ctgtctcggc attattagcc
    47941 cgattgaggt cgttacgggt ttctcgcaaa atcttaaccc gctcaaaatc atcacgtgcc
    48001 tgcatggctc ctattactat caagaagtcc ataatgtctt ctgctcgctg gagataggtc
    48061 acagccccct tcttgcgctc aagcaccttg gcatccagta aaaactgttg gagaagggag
    48121 gcaattcctt gcgcgtggtc cagataaaca gaactgattt ccaactggta cttgcctgac
    48181 tcagggtcac gaatgctccc atttgccaag aaagcgccac agagataggc acgacctgct
    48241 tcctcatccg ataaaatcgc ctcatcaata cctgtttcca ggccaaagaa agagtctgcc
    48301 aagtgcaaat cacttaacaa atcctgcacc ttttcatctg taaaaacggt atagacgcga
    48361 ttcttgcgaa gattgctccg ttggtggtga cgaatttcag atttgatttc atagagatgg
    48421 agaaaggact catagaggtg acgggccagt ttggcatttt ctgtcacaac tgacaaagtc
    48481 aagcccgaag tcgagagacc gatgctacca gacattttga taatggcaga taattcatgc
    48541 cagctcagat ggtgttggcc caggatttct tcttttactg ctactgtgaa actcattttt
    48601 tcacctgtat aatgcgcatc aactcgtcca caatcaaatc tccatcgtgg aaggcaccgc
    48661 cattttccag acgaaggaag ttagatgaaa tcacgcgcga aacttgctta caaagaccta
    48721 caaaatcgtg ttccacttgc actaagtatt catcaaaacg gttggaattc atgtattcct
    48781 gaggcacttt ttcaatattc accaagacag tgtcgataaa agggcgacca aggtgacgat
    48841 gcaagacttc cacgtggtcg ctatctgtaa agtgttccgt ctccccacgt tgggtcatga
    48901 tattgcagac ataggcaatt tctgccttgg tttccaaaag agcccgccca atttccttaa
    48961 tcacgatatt gggcaaaata gaggtaaaga gggaacctgg ccctaggaca atcatgtcac
    49021 tttcaaggat ggtctgcact actcgacggc tggccagagg cgtatcatcg tttagggcat
    49081 tggtcacata gacattgtca attatgcctc gatggtctac aatatgactc tctccagcca
    49141 cttctgtccc atcctgaaag actgcatgaa gggtcaaagg atggtcactg gaaggataaa
    49201 ttttccctgt tgtatggaaa aatttgctca ataactgcat ggcattatag gttgaaccct
    49261 gcatttctga caagccagca atgatgagat ttcccaatgg atggccagca aaggctccgg
    49321 catcctcaga gaaccgatac tgaaagacct tctcataaaa cttaggcata tccgacatgg
    49381 ccacaaggac attacgaaga tcacctggcg gtgtcaactg ttgcatattt tttcggagtt
    49441 cacctgaaga accatcatca tctgccaccg tcacgatagc tgcgatttcc acatcttttt
    49501 cccgcagact ttttagaatg acgggaattc cagtccctcc accaatcacc gttatctttg
    49561 gttttctcat gaacggttta ccgtttcctt tctgcggtct ttgtcgcgat gcccttcatt
    49621 aacagaccaa ttcttggata agtcctgcgc caagcgttta gcaaatgcca cactacggtg
    49681 ttgtccaccc gtacatccca tagcaatggt caaaacggac ttaccttcct tttggtaact
    49741 tggcagaatc ggctcaatca aggccaataa atgttgataa aagtcttctg actcaggatg
    49801 gttcatgaca taatcataaa caggttcatc cacacccgtt tggtttctca gttctggtag
    49861 ataataggga tttggcaaga aacggacatc aaagaccaag tccgcatcaa tcgggattcc
    49921 atacttaaat ccgaaagaca tgacttcgat acggaaagac tgggcttgtt cttggtctga
    49981 aaactgctct gcaagggttt tgcgcagttc acgtggagtg agttcagtcg tatccaccac
    50041 attttggctc atatttttca aaggtgccaa gagttcacgt tccaacttga ttccatctaa
    50101 aatacgaccg tctgctgcta gtgggtgact ccgtctggtt tccttgtaac gagcgaccaa
    50161 ttccttatca gccgcatcca aaaagaggat tttgaaatcc aaaccatctt gattttccaa
    50221 ctcatccaaa acagcttgaa tctctgaaaa gaaagaacgg ctacgcatat ccactaccaa
    50281 agccaactta ggattatctt ccttaatttc aaccagctgc aaaaacttag gcaagagagc
    50341 tggcggcata ttatcaatgg tgaaataacc tagatcctcg aaggactgaa tggctacagt
    50401 tttccctgcg ccactcatcc ctgtcacaat caccaagtga agttgtttct ttgtcatctt
    50461 tttctcctta tatcaaaaga agtttggcaa caccaaactt caactagctt atccaatctc
    50521 tgcgatgact tcaatttcga cttttacatc acgaggaaga cgagctacct ccacagctga
    50581 acgagctggg aattcctctt tgaaggccgt ttggtaaacc tcattaaaag gaacaaagtc
    50641 gttcatatcg ctcaagaagc aagttgtttt gacaacatgg tcaaagtctg ttcctgcttc
    50701 tgccaaaata gcaccgatgt ttttcaagac ttgctctgtc tgttcttgga tattctctcc
    50761 tacaatttcc ccagtttcag gggatagggg aacttgaccg ctagcaaaca aaaggttgcc
    50821 aacgattttt ccttgaacat agggtccgat agcctttggg gccttatctg tatgaattgt
    50881 ttttgccatt ttcttttcct cacaattttt ctaagattgc atcccaagcc tcatccatcc
    50941 ctgccttgct gacagatgaa aagaggatga aatcgtcact tgggtcaaag tttaatttct
    51001 ttttgattgc tgattcatgc ttgttccatt taccacgagg aatcttgtcc gccttggtcg
    51061 ccacaatgat gactggaatc tcataatact tgagaaattc gtacatctgc acatcatctg
    51121 ctgacgggtc atgacgaagg tcaactagac tgacaaccgc acggagattt tcccgagtcg
    51181 ttaagtactc ctcaatcatg cacccccact tttcacgttc ctttttagaa acacgagcat
    51241 agccataacc aggcacatcc acaaagcgca tcttgtcatc aatgttaaaa aagttcagga
    51301 gctgggtttt accaggtttt cctgatgtac gggcgagatt cttacggttc aacatagtgt
    51361 tgataaagct ggatttacca acatttgaac gccctgctag ggcaatctct ggcagttcat
    51421 cctgcggata gtgggactta ttagctgcac tgagcaagat ttcagcattg tgtgtattaa
    51481 gttccatagt cacctctagg ctgtttctag gatcggttta tccgttccat cgacagtttc
    51541 tttagtgatg cgaaccaatt tcacattttc ctgactcggc acctcaaaca taacatctag
    51601 catggtttct tcgataatgg agcgaagtcc acgcgcccct gtcttccgtt cgattgcttt
    51661 attagcaatc tcttgaaggg cttcgtcgtc aaattccaac tcaacatcat cataagaaag
    51721 caaggtttgg tactgtttca ccaaggcatt tcttggctct ttcaagatgc gaaccaagtc
    51781 atcaacggtc aattgctcaa gagccgcaaa aacaggcaag cgtccaatca actcagggat
    51841 aataccaaat ttttgaatgt cttcagcgat gatttcttgc atgtatgagc tgttttcgtc
    51901 aatcgcctta ttgttttgac caaatccgat aactttttca cccagacgtt gtttgacaat
    51961 ttcttcaata ccatcaaaag caccacccac gatgaagagg atattttttg tatccacttg
    52021 aatcatctct tgttgtggat gtttgcgtcc accttgaggc ggcacgctag caacagttcc
    52081 ctcaataatc ttgagaaggg cttgttgcac cccttcacca gaaacatcac gtgtgataga
    52141 cacattctca ctcttcttgg caatcttgtc aatttcatcc acatagataa tgccacgctc
    52201 tgcacgttcg atgttaaagt cagcaacctg caagagtttg aggaggatat tttccacgtc
    52261 ctcacccaca taaccagcct ccgtcagagc tgtcgcatcc gcaatagcaa aaggtacatt
    52321 caagctctta gccaaggtct gggcaaggaa agttttccct gaaccagttg ggccaatcat
    52381 caaaatgttt gacttctgca aatccacatc ttctgactct tcgcgtgtat cgtggaaatt
    52441 gatgcgtttg tagtggttat aaaccgccac tgccaaggca cgcttggcac gatcttgacc
    52501 aattacatag tggttcaaga tatggaggag ttcaattggt tttggcacct cagacaagtc
    52561 tgccaagact tcctcaacca attcttctcg aatgatttcc tgagctaact ccacgcattc
    52621 attacaaata aaagcattgt tgccagcaat tattttttgt acttcttctt ggtttttgcc
    52681 acaaaatgag caataaacca tcatatcatt ttttctattt gtagacatga tttccttcca
    52741 ttctatactg tcattctatc taaaataagg tcatgtaaaa agcatgaata ctattgacca
    52801 gattggtaaa ggcatttaac caaaggagga tagaaagccc gtaacgcttt ttacgaaaag
    52861 cctgtgctcc tgccagaaag cagatgaaac acagaaaagc cgtgaataga ccaaataaac
    52921 tccgttccat tagacttcct ttctcttgcg gtattggatg gtaaaatcat aaggattctt
    52981 ctcatctttg gcgtaaaatt tgcttgaaac tgtctcaaaa agagacaagt caagctcttc
    53041 agggaaatag gtatctcctt ccacccgagc atgaatgtga gtgacaatca cttcatcaag
    53101 gtaaggttca aaagcctgaa aaatttgctt cccaccgata atgtagagat tcttttcttg
    53161 agcctgatac cagtcaagaa cagactggac gtcctgaaaa gtagcaaccc catctatctt
    53221 ttcttccgga ttacgcgtca aaatcaaggt ttcccgtttt ggaagcaagc gacgccccat
    53281 cccatcaaag gtcacacgcc ccatcaagat agcatgattc agagttgttt ctttaaagtg
    53341 ctgcaattct gctggcaaat gccaaggcag acgattttcc ttaccaatca caccctcttc
    53401 atcctgggcc caaatagcta cgattttctt agtcatgctt ccatcctttt cactgatagt
    53461 actattttat caaaaaactc aaaaaaagac tggtttggaa tagcttacaa aatagaaaaa
    53521 atctgtaaga aatttcctac agatttatct atgtttcctt atttcttaca aaccaggtgc
    53581 ttgtccaagt tcggctgcaa gcatccaaat tgttttatct gtttcagttt tagcgcctgc
    53641 aaagataccg tttgtcacat cgtcaccttc ttcatcagtg acatccaaac ctttttggaa
    53701 aagttctgac aagtaacggt agataacaag aacacgttcc aagctttctt caacattacg
    53761 gtattcacca gcttcttctt cgatttcact attttgaagg aactctgtca atgtagagaa
    53821 tgggcttcca ccgagtgtaa tcaagcgttc gctgatttca tccaattgac cgtcaagagc
    53881 ttccatgtac tcatccattt ttggatgcca tacaaggaaa ccacgaccat gcatatacca
    53941 gtgcacttgg tgcaaagcaa cgtgagctac atacaaatca gcaacagctt ggttcaagac
    54001 ttcctttgtt tttgccaatg ctactggcgc tgcttttgtc aatgatgtta cgtcttttac
    54061 tgcttctttt ttcaattcta ccattttctt tacctcattc attatttttt gtaaccactt
    54121 cttaatgatt actaccttag tatactacta aggaaaacca atagcaagac aaagaactta
    54181 tatgagaaaa gttgcaatag actgataatt taagaattct ttagaagaca aaaagagggt
    54241 tggatgctta tagtcaatgg aaatccatca gcaaactagg aaactaaacc cagcttgacc
    54301 aaagcacaag ttttgaggtc gcaggtagaa ctgaccaagc tgatgtggtt tgaagaaatt
    54361 ccccaatact ataatagatt gaaataagat gaaaccaagt cgattaggaa aggtaaatga
    54421 atttctaaaa tgttttacca atcacaaggt atttgtctat attcaatcta ctatataagc
    54481 ttcatttccg agcaagatct tgaatttact cgaggatgaa ctatcataaa acaaaaaaaa
    54541 agagggtgct actatcacat ccctctttca aatcattgct taataccaaa cgctgacatc
    54601 tacgcgccct tggattcctt tcatgtattc agaagaggta tattgccaac ctttttctcc
    54661 tgaataataa gggttttccc attctaaagc attcgtatag gccgctaccc agtttacatg
    54721 ttttaaaata tctgggtgtt ttaaacgcgt ctgtaataaa ctacgatagc tatagacata
    54781 cacattttga taacccgcct gcttcatcgt gtccatgtac ttgttgatga ttttaaccca
    54841 agtgcctgta tcacttggag ctctcttgct cttatttaca tattcccagt tctcaacatc
    54901 ataatagata gggtaagaca ggttcatatt gtatttcttt ataagttcaa tggtctgttt
    54961 agcgtcattc tcagcatcgg tctcattttc agcataggta tagagataga caccataagg
    55021 aattcccaga cggtttaact ccttaatgtt atgcgccaat tccttgtctt ctttgccgct
    55081 ataacctaga cgaacaatga caccatccac ctcgttctca tcaataacct ttttccaatc
    55141 attgatacga ccattgtgct cactaatatc aatgattttc ttagcatgtt cggttcccac
    55201 ttgttcttct ctattattaa agaaatagcg tttaccatct ctgtgaaccc agccgacatt
    55261 caaatctttc ttttctttga gctcaccaga ggccgcaaag atatagcgag caccatccat
    55321 aatcacttcg tcagtcgcca tggcaccact tccagtcaaa tagtagttgc cttgccactc
    55381 attccgagcc atatagcccc acttcttgaa atagtaccat ttgccgccca ctttttgcca
    55441 ctcttggtta gcataagttc catcggattt tagataaaaa taagcagaat aagctggatc
    55501 atagagccat tcattttgta tcatagctcc ttgaccattc aagaaataac ttccttgcca
    55561 ttggctttta gccatgtaac cccacttctt gaagtagtac cacttatttc caatcaattg
    55621 ccattcttga tgagcataag ccccatctga cttgagataa aaccaactct tgtaattact
    55681 gtcatagatc cactcgtttt gggccatata tccacctgat ttcaggtagt aatttccatg
    55741 ccattcattc tgcgagtaac gaccatctga attaatataa aaccaagcct tatagtagtt
    55801 gtcaaaaatc cattcacttt gagctttaga accatcatcc tttacataat aatccccatc
    55861 ccagtaggca gcagcattag tctgtacttc tgcgctcgtt tgcgttttat tagaagactg
    55921 attttgctct gaactacttg aagctgtcgt tgtatcctgc gaagtttttg ctacttcagt
    55981 ttcatttgca gcgacatgac tagttgccaa gcctagtaaa cagatacttg ctaatccaat
    56041 ttttattttc aatctttcct ctcctataaa aaatgtaaca gacatctgaa tgctgttcca
    56101 cctagctttt gctacttact gattatttta caaagtcaag caaagccaag aagctttcag
    56161 cttcaagtga cgcaccacct acaagggcac cgtcaacgtc tgggcaagcc atgtatgaag
    56221 caacattttc aggtttaaca gaaccaccgt attgaacacg aactttgtct gcgacttctt
    56281 gaccaaagtc agcagctaca acgtcacgaa caactttaca cattttttgt gcatcgtctt
    56341 gtgaagctga tttaccagta ccgatagccc agattggctc ataagcgata actgaggcag
    56401 caacttgttc agcagtcaat ccagccaatg cagcagatac ttgagcacct acgaattcag
    56461 cagctttacc agcttcgtaa gtttcaagtg attcaccaca acagatgatt ggaagcatac
    56521 cgttcgcaaa gattgctttt gcttttttgt tgatatcttc atcagtttca tggaagtagt
    56581 cacggcgttc tgagtgaccg ataacaacgt agtcagtacc gatttctttc aaaacttgtg
    56641 ggctagtttc accagtgaaa gcacctgcat tttcaaagta gcagttttga gcagcaactt
    56701 taaggtttga gccttttgca acagcaagaa cagttgtcaa atcaagagct ggagcagcga
    56761 tacctgcttc aacaagatct gatgaaggaa gttttgatgc aactgcttca acgaatgctt
    56821 tagcttcttc tggatttttg ttcattttcc agttaccagc gataaatggt ttacgtgaca
    56881 tttcacatac ctcttttttc aatttatttt ctattttatt ctatcacaat tatacacagc
    56941 ttgcaaatct tactcggatt tcaagcctgc ttgcatggat taatccttcc agagatccat
    57001 ggcatttctg aaatctgcag atacctgtgt caactgagga ttgcttgctt ctctttctgc
    57061 tctcttggcc tcaatttgag ccacactctt gattccttca tggcgccagt ttctcaaaat
    57121 cgcctgaatg tacttccagt ttggttttcc attcaaaaca gcttcacgaa gagcctcctt
    57181 aatcaagtca gcactggttc catcttcctt tagtgtcttg gtcaaatcct caatctcaaa
    57241 aggcgtcaac aatcgtccca actcctgctg gaaggtttcc accaaatcct tgagctggtt
    57301 ttgaggtgtt agctggtctg aacttgaacg aactgctcca aacaggtcat ccaaacgttc
    57361 caaggccaaa ctagcatcaa agaacaattc aatttcgcca tttaattcga tagtacgata
    57421 ctggagcagt cccctttccg tcagattaga aatggactgg ttgacatccg aaatttcctt
    57481 gccaatcctt tcagcaatct ggcttggcga catttcttct aagcctgtcg tattttgcaa
    57541 atagaaaaat tgccaaacca gaaaatcgtc gctagaagga aagagttcct taaaatgcaa
    57601 gagcagggca ctcggtaaaa ccaaggtacc tgatttaaaa gcgtctaaat atgtcataat
    57661 tcctcttata aatacccata tgcagatgca tcatcttcta tctttctcca atcaaaaggc
    57721 gtctcctgat agaccgcatg gtttacccaa ttactgaaaa agagggctgc agatgaagac
    57781 caacaaagac aaggtacctg attaacatca tcatctttaa agtaattttc tggaatatgt
    57841 gggtcgaaac ctgcatcacg atctcgaaaa tactcttttg ccaaggtatc acggtcatac
    57901 tccaaatgac caaaactata aatttctcgt aaatcacgac tggccaaaat agaaacccca
    57961 acctgaggtc cttctgataa aatctcgaga ttggtcttgt ttaagacctc ttccttagaa
    58021 atctccgtgt gccgtgaatg aggggataca tagctatcat caaagcctct aaatagaagg
    58081 tgaccctctt ttagggtgtc ctgaggataa atacctgata gcttactgtc catctggtat
    58141 ttttctacac catagcgcag ataaagccca gcctgagccc cccaacagat atgaagggtc
    58201 gaatagacat gagtcttaga ccactcaagc atctgtctaa attcctccca atagtccact
    58261 tcctcaaatg gtaaatgctc aactggagca cccgtgatga tcatcccatc aaaatactca
    58321 tccttgactt caggaaaagt tttatagaag gtctccatgt gctctgaacg agttgtttta
    58381 gaacggtggc tctccatata gagaaaatca atatccagtt gtaggggtgt attagccaag
    58441 tggcgcaaca actgggtctc tgtgaccatt ttctgtggca tgagatttaa aattaaaatc
    58501 ttcaaaggac ggatatcttg gtgggcagca cgttgatcat ccatgacaaa gatattctct
    58561 gtccgtaaaa tctcaacagc tggcaatttt ttatcaattc gaatcggcat aaccctctcc
    58621 taactgtact ctttcaggaa taattgcata tgtttgaaga caaatctcaa acacttagtc
    58681 cttttattat actgcaagaa gatatagttt tcaattatag tttttctcta actagttata
    58741 gtctattttt atatcctagt gtagagaaaa cagccctggg gactgttttc attaataatg
    58801 cataagaact ttgtagtcgt agtcaccgat tttttcacgg ccgttcaatt catccaattc
    58861 aacaaggaag gcacaacctg ccataacacc accaagtttt tcaatcatct cgatagttgc
    58921 cttaacagtt ccacctgtcg ccaaaaggtc atctacaata agaacacgtt gacctggctt
    58981 aatggcatcc gcgtgcatag tcaaggtatc gacaccgtac tctttttcat agtcagcaga
    59041 aataacttcg cgtggcaatt tacctggctt acgaacaggc gcaaaaccaa ttcccaactc
    59101 aaaggcaact ggacaaccca cgataaatcc acgagcttca ggtcccacga tcatgtcgac
    59161 tttcttgtca gtagcatact gaacgatttc acgaacagcg tagctataag catttccatc
    59221 agccatcaaa ggactaatat cacggaaggt aatgccttcc tttggataat tttcaattgt
    59281 tgcaatgtaa tcttttaaat tcatcttttt ctttctttca aagtttttta ctctctatta
    59341 tagcatattt tttaagaaag aaaaaaggaa aagttaactt caataattat ctaacgtttt
    59401 gacgatttat aactagccat cgcaataaag cccaatttct gtttattctt agcaaacatt
    59461 ttatacatag ttaaaaactg ctttctattc tcctttttac aagcatttac acaaattttc
    59521 aaagttccta gcaaaccttc gtcataaatc atacccgata atttcattaa tgtcatttca
    59581 ccagtcaatg ctttcacatc acaataacct gattctatca tcacctgttc ccaaccatct
    59641 tgagttaaag gacctacatt tacatgaatt gcttgtgata attcctgtct gatagactct
    59701 ttagcttcct taagaagcac atcatgtgtc aagagaagac ctccaggttt taataccctt
    59761 agatattcca ttacacattt tttcttagct tgatcggctt gcatagtcag catagcttca
    59821 tttataacaa tatcaaaact agcatcttga taaggaagtt tcattgcatt tgctctttca
    59881 aaactgatta aatgagcaac acctgccgtt ccagcagatt ttttagccac ttctaaagct
    59941 tgagcatcca tatcaacagc agttatcttg caaccaaaac gctgtgccaa ctcaattgct
    60001 gtagttcccc tattacacgc aacctctagt attctctttt cttttgaaaa tcctccttct
    60061 gcaattaacc aatctgtggc acgctttcca cctggacgta agcgtttttt ccccaatttt
    60121 gctaaaaact tatgacctgc ttctgacatt tgcacacctc tgttttttct tcattataac
    60181 acaaaatgat attatctgac aattctaatc tattatttga taaactagaa tcaaaagcat
    60241 acaagtcacc ataactatag cataaattta ttattacctc tctagttcga attcaattac
    60301 tcacgtagtt tacgcatata gcttcacttg tagatggtac ccacaaataa tactcaatgg
    60361 aaatcaaaga gcaaactagg aaactagccg taagctgctc aaagtacagc tttgaggttg
    60421 cagataaaac tgacgaagtc agtaatcata cgtacggcaa ggcgacgttg acgtggtttg
    60481 aagagatttt cgaagagtat taaagagcat cacaatatag atgcataata tgacttccct
    60541 agcaaaaagg agagaagcat tttgtttctc tccctagatt aactgatatc tctccactac
    60601 aattgataaa gagatatctt ttcttgtagt gctttgaatt ttatttattt tagtagattg
    60661 ttttttcagt ttctacatcg aagaagtgtg ctttgttcaa gtcaaatcca agctcaactg
    60721 ttgcacctgt ttgcaagtag tcacgagcat caacttttgc aacaaactcg tctttaccaa
    60781 cttggcagta aaggtgagat tctgaaccaa gcagttctga tacagagata gtcgctttta
    60841 caacacagtc tgggaatgtt tcaaggaaag caggttctgc attcacgtct tctggacgga
    60901 taccaaagat caattctttt ccttcgtagc ctttttcacg aagaactttc aatgctcctt
    60961 ctggcacttt caaacggaaa ccgtcagaaa caatttcgct accaaccaat ttcacgttga
    61021 tgaagttcat agctgggctt ccgatgaatc ctgcaacgaa tttgttaact ggatttttgt
    61081 aaacttcttg aggagtaccg atttgttcta cacgtccgat agtacctgta ccagcagggt
    61141 tcttagtagc tgacataata acgatacggt ctgcaagtgt catcgcttct gtttggtcgt
    61201 gagttacata gatagttgta gctccgatac gacggtgaat tttagcgatt tcagcacgca
    61261 ttgatacacg aagtttggca tccaagtttg acaaaggttc gtccatcaag aatactttcg
    61321 catcacggac aatcgcacgc cccatggcaa cacgttgacg ttgaccacct gaaaggtcag
    61381 ctggtttacg ttccaagaat tctttcaatc caagtatttc agctgcttct tgaacacgtt
    61441 tgttaatgtc ttctttgctg tatttacgca atttcaaacc gaaagccatg ttgtcataaa
    61501 cagtcatgtg tgggtaaaga gcgtagtttt ggaataccat ggcgatatca cggtcttttg
    61561 gagctacgtc gttgacaacc acgccatcga tagatgcagt accttctgtg atgtcttcaa
    61621 gaccagcaat catacggagt gtagttgatt taccacatcc tgaaggtcct acgaaaacaa
    61681 taaattcttt atctttgatg ttcaagttga aatcttcaac tgaatagtgt tcgctgtttg
    61741 gatatttttt gtaaatattt ttaagattca attctaccat gaggtgaact ccttttgtct
    61801 tttgataatt atattataaa tgaaaacgct ttatatttct atggcaagat gaccaaaaaa
    61861 ataaacaagt tctgtgcaac ttgcacaaaa ctttagagaa tatcggagaa tttgaagaag
    61921 ataatcttta ttattcttct atagacaaaa gcagaaacaa ggatcagttt tcccatattt
    61981 tcgctgattc tccactacat ttgactggat tctaattttt tagagaaata caaaagagct
    62041 agctttagct agctcttttc ctatgcggag agagggactt gaaccctcac gacctaaagc
    62101 ggtcacagga tccttagtcc tgcgcgtctg ccaattccgc catccccgcg tcgattactt
    62161 tactagtata tcaacttttg ggatgcttgt caacactttt tttcaaattt tttcattttc
    62221 accaaccagg ttactcagaa agttcattta gattttcatc tactaactta gctccgagtg
    62281 tatttttgaa atgacctagg gcaaattgat gattttcagg ccagatggaa gcaacagctg
    62341 gtttaacaat ctcgatgtca tatcctagat tataggcatc tatagctgta tgtaggacac
    62401 agatatccgt caagacacct gttaagataa cggtagacac tctacgctct ctcaaacgaa
    62461 tatctaggtc agtccctgaa aaagctgagt aatggcgttt atccatccaa aagacacgac
    62521 tgtctgaacc atgctcttga taaaagatcc ccaaatctcc atataaattc cgtccactcg
    62581 tcccaatcag attatgagga ggaaataact tactttccgg atggaaacaa tcgttttctt
    62641 catgagcatc aatagtaaag aagatataat ctcctcgttc aaaagctaat cgagttacct
    62701 tgctgatggc atccgaaatc gcctgagctg gagcacctgc tgttagtttc ccactatcag
    62761 caacaaaatc ttctgtataa tcaatcgaaa ttaaagcctt tgtcattagt aatctctttt
    62821 cttcacttct tcaaaaatat ctgaaatcaa gaccttaaga taggttccct tcattccaag
    62881 tgagcgactt tcaataatcc ccgcagactc aagtttacga agagcattga caatcacaga
    62941 gcgagtgatt ccgatacgat ctgcaatcac tgacgcagtc aacttccctt catttccatt
    63001 taattcccct aaaattgctg aaacagcacg gagttcggag taagaaaggg tattgaccgc
    63061 catggtgaca gcagtacgac gacgaatatt tttctcatct tcttcacgtt ggaagttaag
    63121 aagctgaatc ccaacaacgg tactggcaat ctcaacaaga accaagtcct catcttcgaa
    63181 ttttttatca ttacgccaaa taatcaaaga accaaggcga atccccgata catgaatcgg
    63241 tgcaatagtc gtcaagccat ctggaaaatc atctctactc tcaacaggga aaatactcat
    63301 atcatgctca acaggcaagt ttgcttctgt ttcgtaaatc atattagccc cttgaacgta
    63361 gtcatctggg aaaatcttag tttggaagaa ttgctctacg cgatctgtat ttgttttata
    63421 acgcataaaa tagccaagca gacgtccctt actattgata atgcaggcat tgcaatgaat
    63481 aatatccgct aactgacgcg taatagcgtt gtaaggaagc tcatcctgca actgctcctc
    63541 tgagcgtttc aaaattgatg taatttttct agttttttct aataaatgtg ccatttttca
    63601 cctcgaattt aatcgctatc attataacat aaaaacgtct ctttttcaat aattatctga
    63661 aaattcctta ttgacttgca ttgacttaca atttaattaa aaaccagaat atttttaatt
    63721 aaattgttcc ttttctattg acaagttgcc tatttttgtg tatcataata ttataaaaga
    63781 taatataata attttatttg tctttttcac attcggtctc cttatataaa aaagcgattc
    63841 attttgaacc gctttttctt atttatcacc tttgttacga ataacaaagc ctgtttgctt
    63901 ttcgcttaaa gtattgcgtg gttttttatt atccttacgg taacgttttt ccttatcaaa
    63961 acgatcgttg ccacgacttc cttttttgaa ctcatcacgg cgaccattgc cacggcgatc
    64021 acgctctcga cggtcgtccc cacgacggcc tccacgacct cccttagctt taccaccgaa
    64081 accattacct gatggtttaa acggtagtgg tttttcacgt gcaatctcca cttctggaag
    64141 gctatctggg tcttggactg tcagactcaa gatatacatt gccaattctt ctggagtaaa
    64201 ctcagcagcc aatttgcgag catccttacc aaatttctca aagttggcac gaatggtttc
    64261 atctgcaaaa tcacgttcga ttttcttgag agctacctgt ttttttgatt ggaaggattc
    64321 ttctacactt gcaggtttga gacctttcat gcgtttctta gtcaagtttt caatgatttg
    64381 aaggtaaccc atttcgtttg gagcaacaaa agtaatagat tgacctgact taccagcacg
    64441 acctgtacga ccgatacggt gaacataact ctcaggatct tgtggaatat cgtagttgta
    64501 gacatgggtc acacctgaaa tatccaaacc acgcgctgca acgtctgtcg caaccaaaac
    64561 atcaagattg ccatttttaa agtcacgaag gacacgaaga cgtttgtttt ggtctaggtc
    64621 gccatgaatt ccttctgcac ggaagccacg aattttcaaa ccacgagtca attcatccac
    64681 acggcgtttg gtacgaccaa atacaatagc gagttctggt tgtgccacat ccatgagacg
    64741 agtcatggtg tcaaattttt cttgttcctt aacacggata tagtactggt caaccaattc
    64801 tgttgtcaat tccttagccg caatcttgac atgttcaggg gctttcataa actgaacacc
    64861 gatacgtttg atggcatctg gcatagttgc tgagaaaagc aaagtttgac ggttctcagg
    64921 tacacgggaa ataatggctt cgatgtcttc aaggaagccc atgttaagca tttcatccgc
    64981 ttcgtcaagg ataagggttt caatgttttg taatttcaag gccttgcgtt taatcaagtc
    65041 caagaggcga cctggagttc ccaccacgat atgggcacca gatttaagag ccttaatttg
    65101 tttttcaatg cttgatccgc catatactga acggactttg actcccttac tacgaccaaa
    65161 gcggaagagt tcttcttgac tttggacagc tagttcacga gttggagcga tgaccaaggc
    65221 ttgaatagtc gcttcttctg tacggatttt ttcaagggta ggcaagccaa aggctgcagt
    65281 ttttcctgta ccagtctgag cttgaccgat aacatccttg ccttcaaggg ccaaaggaat
    65341 agtttgttct tggataggac tagcttctac aaaaccagct ttttcaattt ctgccagcaa
    65401 atcagcagac aagtttaatt cattaaattt cacgttattc ttctttctaa aggtggtgcg
    65461 aagccaccct atagggctta gtttatactt ttctttttat gacgtatttt catataacta
    65521 gatataaaat cgtgttgctt cttttccaca aaagaaaagt actgttttct ttgcaaccta
    65581 tctagtataa cataagacca gagcaaaaga tagccccatt tctacagaaa atcatgtaag
    65641 cggtttttga ctttcttttt tgattgaacg acctagataa taagacaaag ccaaggcgat
    65701 actgtataaa atgagaaaaa cgaacaaggt ttgtgtgtac gaatgagcca ttttataagt
    65761 ctctgctaat aaaataggtc ccgctaaacc agccattgcc caagctgtta aaatataacc
    65821 atgcagagcg gccaattcct tggttccaaa aatatcactg agataagctg gaatcaaaga
    65881 aaaaccagct ccatagcaag tcatcaaaat agacatagcg actacaaata aaacggaatc
    65941 tgtaaagagc caaagtgaga gagaaaagaa aagattaaca agcagtaata tactaaaggt
    66001 tagagggcga ccgatatagt cagataagct cgcccagagc aagcgaccaa atccattgaa
    66061 aatccctaaa acgcccacca ttactgctgc atgacttgta gacaagccag ccatctcctg
    66121 tgccattggc gatgccgctg aaattaagcc taaaccacaa gctatgttga taaagaaaat
    66181 aatccaaagt atataaaacc gattgctttt tagagcctga tttgcagtca tcccttgcgt
    66241 cagagagtct gttttttctt tccctgaagc agataaaatt gcaagctctt gctcatttgg
    66301 acgcttaatg aattgtgaag ctaggagcat gataataaag taacttgcac ctaaaatata
    66361 aaaagtttct acaagcccta cccctgcgat gagatgttgc gctatgggac tagtcaataa
    66421 agaagcaaaa ccaaacccca taatcgctaa acctgttgcg agaccacgtt tatcaggaaa
    66481 ccattttata atcgttgaca caggggtaat atagcctgct cccaaaccaa gcccacctaa
    66541 aatgccataa gctagataca acaaccacag ttcctgacgg tctattgcaa atcctgttaa
    66601 gatatttcca cctgcgtata gaaaagcaga tagactcccc atgactctcg gaccaaattt
    66661 ttctaccaaa cgccccataa atgcagccga taagcccaaa caaaagattg ctagactaaa
    66721 ggcaaaggca acagaagcct gatcccatcc cgttttttca ataatagggt tacgataaac
    66781 actccaagca taagtcgaac ccagcattaa gtgtaaaatg accccagcaa aggcaataat
    66841 ataacgattc gatttcataa aacctcctat tttcgaacat tttttctatc ttatataaaa
    66901 atagatagga ttttagttta tcaagcttgt caaaaaatta ctagtttttt gtctggaaag
    66961 cgtttttatc tttttctgtc ttttccgtag cagaattgtg caaaagtttt tttcttgtgc
    67021 tagaatgaaa tgcgaatagg aggaactcta aatgttaact tatgatttaa tcgttatcgg
    67081 atttggtaaa gctggtaaaa cactagcagg taaattggct tcagctggca aaaaagttgc
    67141 cctcgttgaa cgtagcaaag ctatgtacgg tggaacttgt atcaacatcg gttgtatccc
    67201 aactaaaact ttgctggttg ctgctgagaa agacttgtct tttgaagaag tcattgctac
    67261 caaaaacacg atcactggtc gcctcaacgg taaaaactat acgactgttg ctggtactgg
    67321 cgtcaatatc tttgatgctg aagctcactt cctttcaaat aaagtcatcg aaatccaagc
    67381 tggtgatgaa aaacaagaat tgactgctga aactatcgtc atcaacactg gtgctgtttc
    67441 aaacgtcttg ccaatccctg gacttgctac aagcaaaaac gtctttgact caacaggtat
    67501 ccaaagcttg gataaattgc ctgaaaaact tggagtcctt ggtggcggaa atatcggtct
    67561 tgaatttgct ggcctttaca ataaactagg aagcaaggtt acagtcctag atgccttgga
    67621 tacattccta cctcgtgcag aaccttccat cgcagctctt gctaaacaat acatggaaga
    67681 agacggtatt gaattgcttc aaaatatcca tactactgaa attaaaaacg acggtgacca
    67741 agtgcttgtc gtaactgaag acgaaactta ccgtttcgac gcccttctct acgcaactgg
    67801 acgcaaacca aatgtagaac cacttcaact tgaaaataca gatattgaac taactgaacg
    67861 tggcgctatt aaagtagata aacactgtca aacaaacgtt cctggtgtct ttgcagttgg
    67921 agatgtcaac ggtggtcttc aatttactta catttcactt gatgacttcc gtgttgttta
    67981 cagctacctt gctggagatg gcagctacac acttgaggac cgtctcaatg tgccaaatac
    68041 tatgttcatc acacctgcac tttcacaagt tggtttgact gaaagccaag cagctgattt
    68101 gaaacttcca tacgcagtga aagaaatccc tgttgcagcc atgcctcgtg gtcacgtaaa
    68161 tggagacctt cgcggagctt tcaaagctgt tgttaatact gaaacaaaag aaattcttgg
    68221 tgcaagcatc ttctcagaag gttctcaaga aatcatcaac atcattactg ttgctatgga
    68281 caacaagatt ccttacactt acttcacaaa acaaatcttc actcacccaa ccttggctga
    68341 gaacttgaat gacttgtttg cgatttaagt tgaaatctca tcttaactga cagccctctt
    68401 tgggctgttt ttacttctac gaaacaccaa atctgtcttt tccctctttt gtgatataat
    68461 agaaacatga acttaaaaac tactttgggc cttcttgctg ggcgttcttc ccacttcgtt
    68521 ttaagccgtc ttggacgtgg aagtacgctc ccaggtaaag tcgcccttca atttgataaa
    68581 gatattttac aaaacctagc taagaactac gagatggtcg ttgtcactgg aacaaatgga
    68641 aaaaccctga caactgccct cactgtcggc attttaaaag aggtttatgg tcaagttcta
    68701 accaacccaa gcggtgccaa catgattaca gggattgcaa caaccttcct aacagccaaa
    68761 tcttctaaaa ctggaaaaaa tattgccgtc ctcgaaattg acgaagccag tctatctcgt
    68821 atctgtgact atatccagcc tagtcttttt gtcattacta atatcttccg tgaccagatg
    68881 gaccgtttcg gtgaaatcta tactacctat aacatgatat tggatgccat tcggaaagtt
    68941 ccaactgcta ctgttctcct taacggagac agtccacttt tctacaagcc aactattcca
    69001 aaccctatag agtattttgg ttttgacttg gaaaaaggac cagcccaact ggctcactac
    69061 aataccgaag ggattctctg tcctgactgc caaggcatcc tcaaatatga gcataatacc
    69121 tatgcaaact tgggtgccta tatctgtgaa ggttgtggat gtaaacgtcc tgatctcgac
    69181 tatcgtttga caaaattggt tgagttgacc aacaatcgct ctcgctttgt catagacggc
    69241 caagaatacg gtatccaaat cggcgggctc tataatatat ataacgccct agctgctgtg
    69301 gccatcgccc gtttcctagg tgccgattcg caactcatca aacagggatt tgacaagagc
    69361 cgtgctgtct ttggacgcca agaaaccttt catatcggtg acaaggaatg tacccttgtc
    69421 ttgattaaaa atccagtcgg tgcaacccaa gctatcgaaa tgatcaaact agcaccttat
    69481 ccatttagcc tatctgtcct ccttaatgcc aactatgcag atggaattga cactagctgg
    69541 atctgggatg cagactttga gcaaatcact gacatggaca ttcctgaaat caacgctggc
    69601 ggtgttcgtc attctgaaat cgctcgtcgc ctccgagtga ctggctatcc agctgagaaa
    69661 atcactgaaa cgagtaatct ggagcaagtt ctcaagacca ttgagaatca agactgcaag
    69721 catgcctata ttctggcaac ttatactgcc atgctggaat ttcgtgaact gctggctagt
    69781 cgtcagattg ttagaaagga gatgaactaa tggtttatac ttcactttcc tcaaaagatg
    69841 gcaattaccc ctatcagctc aacattgccc acctctacgg aaatctcatg aatacctacg
    69901 gggacaatgg aaacatcctc atgctcaagt atgtggctga aaaactggga gcccatgtga
    69961 ccgttgacat cgtttctctc catgatgact ttgatgaaaa tcactacgac atcgcctttt
    70021 tcggtggtgg tcaagacttt gaacaaagta tcattgcaga cgacctacct gctaaaaaag
    70081 agagcattga caactacatc caaaacgacg gtgtagttct ggctatctgc ggtggtttcc
    70141 aactattggg tcaatattat gttgaagctt caggaaaacg tatcgaaggg ctaggggtca
    70201 tgggacacta cacgctcaac cagaccaata accgttttat cggtgacatc aagattcaca
    70261 atgaagattt cgatgaaacc tactatggat ttgaaaatca ccaaggccgt accttcctct
    70321 ctgatgacca aaaaccgctg ggacaggttg tctatggaaa tggaaacaac gaagaaaagg
    70381 tcggtgaagg ggttcattat aagaatgtct ttggttccta cttccacggg cctatcctct
    70441 ctcgtaatgc caatctggct tatcgcctag ttactactgc cctcaagaag aaatatggtc
    70501 aggatatcca actccctgcc tatgaggata tcctcagcca agaaatcgct gaagagtaca
    70561 gtgacgtcaa aagcaaggct gacttttctt aaacaaagga aaatgatatc aaagaactcc
    70621 gttatcttgt cggagttttt tgtcttttct tttacccttc tcccttgcat tttctctcat
    70681 tttttgccaa aatagagggg tagaaagaag gtagcatatg tctaaattac aacaaatcct
    70741 aacatatctt gaatcagaaa aactagacgt cgctgtcgta tctgaccccg tcacaatcaa
    70801 ttacctcact ggtttttaca gtgatcccca tgaacgccaa atgttcctct ttgtcctagc
    70861 ggatcaggaa cctctcctct ttgtcccagc tcttgaagta gaacgtgcaa gtagcaccgt
    70921 ttccttccca gtagtgggct atgtcgattc tgaaaatcca tggcaaaaaa tcaaacatgc
    70981 tcttccacaa cttgacttca aacgtgtcgc tgttgagttt gacaatctca tcttgaccaa
    71041 ataccatggt ttgaaaacaa tttttgaaac tgctgagttt gaaaacctca ctcctcgtat
    71101 ccaacgcatg cgcctcatca aatcagctga tgaagtacaa aaaatgatgg ttgcaggtct
    71161 ttatgctgac aaggctgttc atgttggttt tgacaatatt tctcttgata agactgagac
    71221 agatatcatc gcacaaattg actttgccat gaaacgtgaa ggttacgaaa tgagctttga
    71281 taccatggtc ttgactggtg ataatgctgc gaatccacac ggcattccag cagctaataa
    71341 ggttgaaaat gatgctcttc tcctctttga cctgggggtt ctggtcaatg gctatgcgtc
    71401 agatatgact cgtacagtcg ctgtcggcaa accagaccaa ttcaagaaag atatttacaa
    71461 cttgactctt gaagcccaac aagctgctct tgactttatc aagccaggtg tgactgctca
    71521 tgaagtggac cgcgctgccc gtgagatcat cgaaaaagct ggttatggtg agtacttcaa
    71581 ccaccgtctc gggcatggta tcggtatgga tgtccatgaa ttcccatcta tcatggaagg
    71641 aaacgacatg gtcatcgaag aaggcatgtg cttctctgtt gaaccaggta tctatatccc
    71701 tggtaaagtc ggtgttcgta ttgaagactg cggtgttgtt accaaggatg gcttcgacct
    71761 ctttacaagc accagcaaag atttgcttta ttttgattaa actatatagc ccctatgctt
    71821 tcctttcaaa atatctaggg gctattttat tgtcattttt ctgctattat gctaaagaaa
    71881 ttggctgcaa taatctaacc ctaagtgtct ggaatgataa cgagggtgct ctccgctttt
    71941 atcaaagaca agggatgaaa ccccaagaaa caacaatgga aatgataatt gattaagaag
    72001 tcatctatca aaagatgtta gaaaaagttc aatttcacta gaaaatgagg aaaatcttcc
    72061 cacaataaaa cgcatattat caagtgttaa aatgtaccgc cccccaaaag ttagacaatt
    72121 aatttatcca aaggatttag ttctgtactg cacaggacta agtcctttta gttttacctt
    72181 aattcgttta ttgttgtagt aatcaatata gtctacaata gcttgttcca attgattaag
    72241 tgatttaaat gttttctcat agccataaat ttcagaatcc caaagaagga ctccatcata
    72301 ccgttgtctt ggctgtttcc cttgcgtgac atggatgctt gaattccctt actctctaag
    72361 aaccgatgat aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc
    72421 tcgtagtact tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt
    72481 gaagttgaaa gattataggc gataatttcg ctgttaaaac catctaaaac tggtgataag
    72541 taaagctttt gagtacttgc tggaatggca aattctgtca tatctgtgta gcacttttcc
    72601 attgttttag agccttcaaa ttggccttga atgagattct ctgccttctt accaacgtct
    72661 cctttatgag aagaatattt tcgtttctgt cgcattttag tttgtaaatt gagtactttc
    72721 atcaagcctt gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga
    72781 acccggcgat aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta
    72841 agctcttggt ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtcgaacga
    72901 gctagtttaa tggcttttag aagaagatct aacgaaaact cagtcattaa ttcttgaaca
    72961 atttctgtct ttcttctttc tctttttcct ccttcaatcg gagttctctt aactttttta
    73021 ggatggcatt ctccgctctc aggtactcat tttctgcttg aagacgttct aattctgtcc
    73081 tctcttcagg tct
//
LOCUS       DBEJJE010000005        58640 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEJJE010000005 DBEJJE010000000
VERSION     DBEJJE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 58640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.05"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..70)
                     /locus_tag="ACL3F5_000320"
     CDS             complement(<1..70)
                     /locus_tag="ACL3F5_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0514186.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEK"
     gene            complement(166..1146)
                     /gene="dusB"
                     /locus_tag="ACL3F5_000321"
     CDS             complement(166..1146)
                     /gene="dusB"
                     /locus_tag="ACL3F5_000321"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0514187.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1133..2005)
                     /gene="hslO"
                     /locus_tag="ACL3F5_000322"
     CDS             complement(1133..2005)
                     /gene="hslO"
                     /locus_tag="ACL3F5_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0514188.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2170..3597
                     /locus_tag="ACL3F5_000323"
     CDS             2170..3597
                     /locus_tag="ACL3F5_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0514189.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHHIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3756..5264
                     /gene="glpK"
                     /locus_tag="ACL3F5_000324"
     CDS             3756..5264
                     /gene="glpK"
                     /locus_tag="ACL3F5_000324"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0514190.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5306..7132
                     /gene="glpO"
                     /locus_tag="ACL3F5_000325"
     CDS             5306..7132
                     /gene="glpO"
                     /locus_tag="ACL3F5_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0514191.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7202..7906
                     /locus_tag="ACL3F5_000326"
     CDS             7202..7906
                     /locus_tag="ACL3F5_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0514192.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8203..8407
                     /locus_tag="ACL3F5_000327"
                     /pseudo
     CDS             8203..8407
                     /locus_tag="ACL3F5_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8494..9081)
                     /locus_tag="ACL3F5_000328"
     CDS             complement(8494..9081)
                     /locus_tag="ACL3F5_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514193.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            9235..9432
                     /locus_tag="ACL3F5_000329"
     CDS             9235..9432
                     /locus_tag="ACL3F5_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514194.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            10246..11523
                     /gene="ltrA"
                     /locus_tag="ACL3F5_000330"
     CDS             10246..11523
                     /gene="ltrA"
                     /locus_tag="ACL3F5_000330"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGR0514195.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGMTIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            11979..13157
                     /locus_tag="ACL3F5_000331"
     CDS             11979..13157
                     /locus_tag="ACL3F5_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGR0514196.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13471..13602
                     /locus_tag="ACL3F5_000332"
     CDS             13471..13602
                     /locus_tag="ACL3F5_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0514197.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13623..15173
                     /gene="dltA"
                     /locus_tag="ACL3F5_000333"
     CDS             13623..15173
                     /gene="dltA"
                     /locus_tag="ACL3F5_000333"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0514198.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQSLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15170..16414
                     /gene="dltB"
                     /locus_tag="ACL3F5_000334"
     CDS             15170..16414
                     /gene="dltB"
                     /locus_tag="ACL3F5_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0514199.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16428..16667
                     /gene="dltC"
                     /locus_tag="ACL3F5_000335"
     CDS             16428..16667
                     /gene="dltC"
                     /locus_tag="ACL3F5_000335"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0514200.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVIEFGRDDWNTANKIIAGIVELQNA"
     gene            16660..17928
                     /gene="dltD"
                     /locus_tag="ACL3F5_000336"
     CDS             16660..17928
                     /gene="dltD"
                     /locus_tag="ACL3F5_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0514201.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18083..18523
                     /gene="adcR"
                     /locus_tag="ACL3F5_000337"
     CDS             18083..18523
                     /gene="adcR"
                     /locus_tag="ACL3F5_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0514202.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18523..19227
                     /locus_tag="ACL3F5_000338"
     CDS             18523..19227
                     /locus_tag="ACL3F5_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0514203.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19220..20026
                     /locus_tag="ACL3F5_000339"
     CDS             19220..20026
                     /locus_tag="ACL3F5_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0514204.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20036..21541
                     /gene="adcA"
                     /locus_tag="ACL3F5_000340"
     CDS             20036..21541
                     /gene="adcA"
                     /locus_tag="ACL3F5_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0514205.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22669..23442)
                     /locus_tag="ACL3F5_000341"
     CDS             complement(22669..23442)
                     /locus_tag="ACL3F5_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0514206.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            23618..25021
                     /locus_tag="ACL3F5_000342"
     CDS             23618..25021
                     /locus_tag="ACL3F5_000342"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0514207.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25136..25774
                     /locus_tag="ACL3F5_000343"
     CDS             25136..25774
                     /locus_tag="ACL3F5_000343"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0514208.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            25786..26226
                     /locus_tag="ACL3F5_000344"
     CDS             25786..26226
                     /locus_tag="ACL3F5_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0514209.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26219..26650
                     /locus_tag="ACL3F5_000345"
     CDS             26219..26650
                     /locus_tag="ACL3F5_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0514210.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26641..27111
                     /locus_tag="ACL3F5_000346"
     CDS             26641..27111
                     /locus_tag="ACL3F5_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0514211.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27136..27909
                     /locus_tag="ACL3F5_000347"
     CDS             27136..27909
                     /locus_tag="ACL3F5_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0514212.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27906..28706
                     /locus_tag="ACL3F5_000348"
     CDS             27906..28706
                     /locus_tag="ACL3F5_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0514213.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28765..31059
                     /locus_tag="ACL3F5_000349"
     CDS             28765..31059
                     /locus_tag="ACL3F5_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0514214.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31069..34185
                     /locus_tag="ACL3F5_000350"
     CDS             31069..34185
                     /locus_tag="ACL3F5_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0514215.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGKYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYDHHSVTHTKGNSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34242..36008
                     /locus_tag="ACL3F5_000351"
     CDS             34242..36008
                     /locus_tag="ACL3F5_000351"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0514216.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEVAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRIDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVVKMFMIGRDLTQGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPVVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36154..37305
                     /locus_tag="ACL3F5_000352"
     CDS             36154..37305
                     /locus_tag="ACL3F5_000352"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0514217.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37449..38333
                     /locus_tag="ACL3F5_000353"
     CDS             37449..38333
                     /locus_tag="ACL3F5_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0514218.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38687..38938
                     /locus_tag="ACL3F5_000354"
     CDS             38687..38938
                     /locus_tag="ACL3F5_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0514219.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            38926..39216
                     /locus_tag="ACL3F5_000355"
                     /pseudo
     CDS             38926..39216
                     /locus_tag="ACL3F5_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
     gene            complement(39443..39526)
                     /locus_tag="ACL3F5_000356"
                     /pseudo
     CDS             complement(39443..39526)
                     /locus_tag="ACL3F5_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(39620..40951)
                     /locus_tag="ACL3F5_000357"
     CDS             complement(39620..40951)
                     /locus_tag="ACL3F5_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0514220.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(40973..42484)
                     /locus_tag="ACL3F5_000358"
     CDS             complement(40973..42484)
                     /locus_tag="ACL3F5_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0514221.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42695..43642)
                     /gene="arcC"
                     /locus_tag="ACL3F5_000359"
     CDS             complement(42695..43642)
                     /gene="arcC"
                     /locus_tag="ACL3F5_000359"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0514222.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43807..44823)
                     /gene="argF"
                     /locus_tag="ACL3F5_000360"
     CDS             complement(43807..44823)
                     /gene="argF"
                     /locus_tag="ACL3F5_000360"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0514223.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(44881..46110)
                     /gene="arcA"
                     /locus_tag="ACL3F5_000361"
     CDS             complement(44881..46110)
                     /gene="arcA"
                     /locus_tag="ACL3F5_000361"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0514224.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            46865..48544
                     /locus_tag="ACL3F5_000362"
     CDS             46865..48544
                     /locus_tag="ACL3F5_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0514225.1"
                     /translation="MKKIKPHRPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48584..50668)
                     /locus_tag="ACL3F5_000363"
     CDS             complement(48584..50668)
                     /locus_tag="ACL3F5_000363"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0514226.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAT
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            50840..52120
                     /locus_tag="ACL3F5_000364"
     CDS             50840..52120
                     /locus_tag="ACL3F5_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0514227.1"
                     /translation="MVYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52211..54856
                     /locus_tag="ACL3F5_000365"
     CDS             52211..54856
                     /locus_tag="ACL3F5_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0514228.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFELFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVQLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTSFTSLQLARQEGS
                     VVAIGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            54940..55809
                     /locus_tag="ACL3F5_000366"
     CDS             54940..55809
                     /locus_tag="ACL3F5_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0514229.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55803..57683
                     /locus_tag="ACL3F5_000367"
     CDS             55803..57683
                     /locus_tag="ACL3F5_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0514230.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58009..58335
                     /locus_tag="ACL3F5_000368"
                     /pseudo
     CDS             58009..58335
                     /locus_tag="ACL3F5_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(58387..>58640)
                     /locus_tag="ACL3F5_000369"
     CDS             complement(58387..>58640)
                     /locus_tag="ACL3F5_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0514231.1"
                     /translation="GYQGLMKIYPQVQTPRKSSKLKPLTAENKAYNHALSKERSKVEN
                     IFAKVKTFKIFSTTYRNHRKRFGLRMNLSAGIINHELGF"
BASE COUNT        17679 a        10742 c        12892 g        17327 t
ORIGIN      
        1 gcttctctaa gctatatcct tgttttctaa gttcatagat ctgaacttta tcatcataag
       61 ttaatttcat aataaaaaca ccccaaaagt tagatttttt ctgtctaact tttggggtgc
      121 agttcatttt gagctttccc gtttttctga gttgtagatg taagactatg ccttctccaa
      181 ttgcaagagg gcttcaatct ctgctagggt gctagcttgc gaaatggctc cacggagttt
      241 ggcagcgcca gatgttccac ggagatagtg aggagcgagg ccgcggaatt cacgaactgc
      301 gacgttttct cctttgaggt taatcaatcg tttcaagtgt tcgtaggcga tcttcatctt
      361 gtcttcaaag gtcaaatcag gtaggatttc tcctgtttca aagtaatggt tgatttggtt
      421 gaagaggtaa ggatttccca tggcagctcg gccaatcatg actgcgtcag caccaacttc
      481 ttcgatgcgt tgcttggctt cttggacagt acggatatca ccgttggcga tgaatggaat
      541 cttggttaga gcttgggcaa ccttgtaaag ggtctcaagg tctgcgtggc cagtatacat
      601 ttgttcacgg gtacggccat gcatggcgag ggcagaaaca cctgcagcct cagcagcgag
      661 ggcattttct actgccagag atgggtccgc ccagccggta cgcattttga cagtaagtgg
      721 gatatcaagg acagactgga ccttgttgat gatagagtag atcttgtcag gatccttgag
      781 ccacatagca ccagcttcgt tcttcacgat tttgttgaca gggcagccca tgttgatatc
      841 gacgatatcg gtcttagtgt tttcttggat aaattctgct gcgcgtgcta ggctgtcttc
      901 atcgctacca aaaagttgga tagagacagg gttttcgccc tcatcgatat gaagcatgtg
      961 cagggttttt tcgttgttgt attggattcc cttgtcagag accatttcca ttacaacgag
     1021 tccagctccg agctcttttg cgatggtacg aaaggctgag ttggtcacgc cagccatagg
     1081 cgctaaaacg gtacgattgg gaatctcaac attgccaatc ataaaaggtg tattaagatt
     1141 tgtcacgaat gagttcctcc aggtcctttt catcaaagtt gtaagtagtt tggcagaatt
     1201 gacaagtgat ttctaccccg tggtcttcct ctttcatttc ctgtaagtct gagcttggaa
     1261 ggctggcaag agcgttcata aagcgttcat ggctacagtc acattggaaa cggatttctt
     1321 cttcagaaag acgcttgtag gcttcgtccc cgtagatagc cttgaggagg gcttcgatat
     1381 ggtcgtcgct ttcgagaaga gtagagatag ctggcatttc ttggatgcgt ttttcaaagc
     1441 gagcaatctc ttctttcttg gctcctggca agacttgaac taggaaacca cctgcaatct
     1501 tgaccttgtc ttcctcgtcc aaaaggacat tgaggccgac cgctgaaggc gtttgttggc
     1561 tttcagtaag gtaaaaggca aggtcttcac cgatttctcc agagatgagg ggagttatag
     1621 agttgtaagg atttccagta ccgtagtctg tgataacgag gaattgacca tttccaacaa
     1681 aaggtccgac taggacttca ccagtcgcag tctttttgat gtcaacacca ggattttgaa
     1741 cgtagccttt gacgttcccc ttggtatcag cgacggtgat aatagcacct agagagctag
     1801 atcccaacac cttaactgta agtttggtat ttcctttttc attggctgcg agaatctggc
     1861 tggcgataag agttcgacca agcgctacag ttgagctagc ttgggtttga tgtttttctt
     1921 gagcagtgcg gacggtttca gtgctatcaa ggacaaaagc acgaaaggct ccgctttctg
     1981 atatagtttt aataatttta tccatagcta ctattttagc ataaaaatgc ccaaaggggg
     2041 agccgtgtgt ttactgattt tcaggataat ggaccaggaa atcagcatga aaataaaaag
     2101 agaaacagat tatttcagca tttgtcagat ttatgctatg cttaaggtag aaaatgaaag
     2161 gggtaacaaa tgtatttagg agatttgatg gagaaagccg agtgtggtca attttcaatc
     2221 ctttcctttc tattacaaga gtctcagacg actgtcaagg ctgtaatgga agaaacagga
     2281 ttttcaaaag caaccctaac caaatatgtc accctgctca atgacaaggc tttggatagt
     2341 ggcttagagc tgactattca ctcagaagat gaaaatctgc gtctgtctat cggtgcagct
     2401 accaagggga gagatattcg gagcttgttt ttggagagtg ctgttaaata ccagattttg
     2461 gtttatcttc tctaccacca acagttttta gcccatcagc tggctcaaga attggtgatt
     2521 agcgaggcta cgcttggtcg tcacttggct ggtttaaatc agattttgtc agaatttgat
     2581 ttatccatcc aaaatggacg ttggcgaggt ccagagcatc atattcgcta tttctatttc
     2641 tgtcttttcc gaaaggtctg gtcgagtcag gaatgggaag gtcacatgca gaaaccagag
     2701 agaaaacagg agattgccaa tttagaggaa atctgcggtg caagtttgtc tgtggggcag
     2761 aaattggact tggttctctg ggctcacatc agtcaacaac gtcttcgggt caatgcttgt
     2821 cagtttcaag tcatagaaga gaaaatgcga gggtattttg acaatatctt ctatcttcgt
     2881 ttgctgagaa aggttccgtc cttttttgct gggcaacata ttccactagg agttgaggat
     2941 ggtgagatga tgatattctt ctcttttctc ctatctcatc gcattcttcc tcttcatact
     3001 atggagtata ttcttggttt tggagggcag ttggcagatt tactgacgca attgattcaa
     3061 gaaatgaaga aggaggaact attgggggat tatacagagg accatgtcac ctatgaactc
     3121 agtcagcttt gtgctcaagt ctatctctat aagggctata ttttacagga tcgctacaag
     3181 taccagttag agaatcgtca tccatattta ctgatggaac atgattttaa agagacagca
     3241 gaggagattt ttcatgctct acctgctttt caacagggga cagatttaga taagaagatt
     3301 ctctgggaat ggctccagtt aatcgaatat atggctgaaa acggtggcca gcatatgcgg
     3361 attggtctgg atttgacatc tggttttctt gtcttttcaa ggatggcagc cattttgaaa
     3421 cggtatttgg aatacaatcg ttttattacc attgaagcct atgaccctag tcggcattat
     3481 gatttgctgg ttaccaataa cccgattcat aagaaggaac agacaccagt ctattattta
     3541 aaaaatgact tggatatgga ggatttggta gcgattcgcc agttattatt cacttaaaag
     3601 gcttggttaa tccaggtctt ttttgtgaaa ttcacacaat ctcctcacat ttttttaaaa
     3661 attaaaaaaa gttgataaac aagaaagcgc tttattttgt atactagtaa gtgtaaagag
     3721 gaaacacctc aagatcttta tcaggaggac agtacatgtc acaagaaaaa tacatcatgg
     3781 ccattgacca gggaactaca agttctcgtg ccatcatttt caacaaaaaa ggggaaaagg
     3841 ttagctcgag tcaaaaagag tttacccaga ttttccctca ggcaggttgg gttgagcaca
     3901 atgccaatga aatttggaac tctgttcagt cagttattgc gggtgctttc atcgaaagtg
     3961 gtgtcaagcc aaatcaaatc gaggcaatcg ggattaccaa ccaacgtgaa acaacggttg
     4021 tctgggataa gaaaacagga cttcctatct acaatgctat cgtttggcag tcacgccaga
     4081 cagcaccttt ggctgagcaa ctaaaaagcc aaggttatgt ggaaaaattc catgaaaaga
     4141 ctggtttgat tattgatgct tacttctctg ctaccaaggt tcgttggatt ttggatcatg
     4201 tagaaggtgc tcaagagcga gcagaaaaag gggaattgct ctttggtact atcgatactt
     4261 ggttggtttg gaaattgact gacggtgcgg ctcacgtgac tgactactca aatgcagctc
     4321 gtaccatgct ttataacatt aaagaactca aatgggatga tgagattttg gaaatcctta
     4381 acattccgaa ggctatactt ccagaagttc gttctaactc cgaaatctac ggcaagacag
     4441 ctccattcca tttctacggt ggagaggtgc caatctcagg tatggctggg gaccaacaag
     4501 cagccctctt tggacagttg gcttttgagc caggtatggt taagaatact tatggaacag
     4561 gctctttcat catcatgaat actggggaag agatgcagtt gtctgaaaac aacctcttga
     4621 caaccattgg ttacggaatc aacggtaagg tttattatgc cttggaaggt tctatcttca
     4681 tcgcaggaag tgctattcag tggcttcgtg acggtcttcg catggttgaa aattcaccag
     4741 aatctgaaaa atacgctcgt gattctcaca acaacgatga agtttatgtc gttccagcct
     4801 ttacaggtct aggcgctcca tactggaacc aaaatgctcg tggttccgtc tttggtttga
     4861 ctcgtggaac aagcaaagaa gactttatca aggcgacttt gcaatctatt gcttatcaag
     4921 tgcgtgacat catcgacacc atgcaaatgg atactcagac cgccattcaa gtactgaagg
     4981 tggatggtgg tgcagccatg aacaacttcc tcatgcagtt ccaggcggat attttaggca
     5041 ttgacattgc acgtgctaaa aacttggaaa caacagctct aggagcggcc ttcctagcag
     5101 gtttgtcagt agggtactgg aaagacttgg acgagttgaa actcttgaac gagacaggag
     5161 aactctttga gccatctatg aatgaatctc gcaaggaaca actctacaag ggctggaaga
     5221 aggctgtgaa agcaactcaa gtctttgcgg aagtagacga ctaatactgg cagaataaag
     5281 cgatttattt agaaagtgtg taaatatgga attttcaaaa aaaacacgtg aattgtcaat
     5341 taaaaaaatg caggaacgca ccctggacct cttgattatc ggtggaggaa tcacaggagc
     5401 tggtgtagcc ttgcaggcgg cagctagcgg tcttgagact ggtttgattg aaatgcaaga
     5461 ctttgcagaa ggaacatcta gtcgttcaac aaaattggtt cacggaggac ttcgttacct
     5521 caaacaattc gacgtagaag tggtctcaga tacggtttct gaacgtgcag tggttcaaca
     5581 aatcgctcca cacattccaa aaccagaccc aatgctctta ccagtttacg atgaagatgg
     5641 agcaaccttt agcctcttcc gtctcaaagt agccatggac ttgtacgacc tcttagcagg
     5701 tgtgagcaac acaccaactg cgaacaaggt tttgagcaag gatcaagtct tggaacgcca
     5761 gccaaacttg aagaaggaag gcttggtagg aggtggagtg tatcttgact tccgtaacaa
     5821 cgatgcgcgt ctcgtgattg aaaacatcaa acgtgccaac caagacggtg ccctcattgc
     5881 caaccacgtg aaggcagaag gcttcctctt tgacgaaagt ggcaagatta caggtgttgt
     5941 agctcgtgat ctcttgacag accaagtatt tgaaatcaag gcccgtctgg ttattaatac
     6001 aacaggtcct tggagtgata aagtacgtaa tttgtctaat aagggaacgc aattctcaca
     6061 aatgcgccca actaagggag ttcacttggt agtggattca agcaaaatca aggtttcaca
     6121 gccagtttac tttgacacag gtttgggtga cggtcgtatg gtctttgttc tcccacgtga
     6181 aaacaagact tactttggta caactgatac agactacaca ggtgatttgg agcatccaaa
     6241 agtaactcaa gaagatgtag attatctact tggcattgtc aacaaccgct ttccagaatc
     6301 caacatcacc attgatgata tcgaaagcag ctgggcaggt cttcgtccat tgattgcagg
     6361 gaacagtgcc tctgactata atggtggaaa taacggtacc atcagtgatg aaagctttga
     6421 caacttgatt gcgactgttg aatcttatct ctccaaagaa aaaacacgtg aagatgttga
     6481 gtctgctgtc agcaagcttg aaagtagcac ctctgagaaa tatttggatc catctgcagt
     6541 ttctcgtggg tctagcttgg accgtgatga caatggtctc ttgactcttg ctggtggtaa
     6601 aatcacagac taccgtaaga tggctgaagg agctatggag cgcgtggttg acatcctcaa
     6661 agcagaattt gaccgtagct ttaaattgat caattctaaa acttaccctg tttcaggtgg
     6721 agaattgaac ccagcaaatg tggattcaga aatcgaagcc tttgcgcaac ttggagtttc
     6781 acgtggtttg gatagcaagg aagctcatta cctagcaaat ctttacggtt caaatgcacc
     6841 gaaggtcttt gcacttgctc acagcttgga acaagcgcca ggtcttagct tggcagacac
     6901 cttgtccctt cactatgcaa tgcgcaatga gttgactctt agcccagttg acttccttct
     6961 tcgtcgtacc aatcacatgc tctttatgcg tgatagcttg gatagtatcg ttgagccaat
     7021 tttggatgaa atgggacgat tctatgactg gacagaagaa gaaaaagcaa cttaccgtgc
     7081 tgatgtcgaa gcagctctcg ctaacaacga tttagcagaa ttaaaaaatt aagaaaaaat
     7141 aaaagaggtg gagggcagca ttccttgtcg cccgtccctt ctttttaatg gagacagaaa
     7201 gatgatgaat gaattatttg gagaatttct agggacttta atcctgattc ttctaggaaa
     7261 tggtgttgtt gcaggtgtgg ttcttcctaa aaccaagagc aatagctcag gttggattgt
     7321 gattactatg ggttggggga ttgcagttgc ggttgcagtc tttgtatctg gcaagctcag
     7381 tccagcttat ttaaacccag ctgtgaccat cggtgtggcc ttaaaaggtg gtttgccttg
     7441 ggcttccgtt ttgccttata tcttagccca gttcgcaggg gccatgctgg gtcagatttt
     7501 ggtttggttg caattcaaac ctcactatga ggcagaagaa aatgcaggca atatcctggc
     7561 aaccttcagt actggaccag ccatcaagga tactgtatca aacttgatta gtgaaatcct
     7621 tggaaccttt gttttggtgt tgacaatctt tgctttgggt ctttacgatt ttcaggcagg
     7681 tatcggaacc tttgcagtgg gaactttgat tgtcggtatc ggtctatcac taggtgggac
     7741 aacaggttat gccttgaacc cagctcgtga ccttggacct cgtatcatgc acagcatctt
     7801 gccaattcca aacaagggag acggagactg gtcttacgct tggattcctg ttgtaggccc
     7861 tgttatcgga gcagccttgg cagtgcttgt attctcactt ttctagttta tactcttcga
     7921 aaatcaaatt caaaccacgt cagcgtcgcc ttaccgtact caagtacagc ttgcggctag
     7981 cttcctagtt tgctctttga ttttcattga gtattagaaa acaattatgt tgatagagct
     8041 tgggcaagag cccaatttca gcaaaaaatg aagtaaatct tctcataata aaacgcatca
     8101 tatcaagcac gaaaattcca cgaggtcaac tacagtcaga aagctgaaca acaagccaaa
     8161 acgcccaaaa aaggcggcaa aaagcaagca cctgcaagca acgtgccgaa atggtcaaat
     8221 cctgattatg tcaacgaatt agacccaaaa atcgttgata tgctagtaga atttcacaag
     8281 tcacaaggca ctttggaaac tcccgaggcg caagcagaaa tcgcccaaaa acgtgaagaa
     8341 atcgagcaaa ggagagctga gcttgaggat aaaaaaacaa gagcttttga accgcttgaa
     8401 caaatagagt ttcgcaagta ttatgcttac aaattacttg agcaattaac taaaatataa
     8461 accctgcctt tatatctagg cagggtttat attttagaaa ttcacgtagg ttgttacggt
     8521 ttttacatac ccagtatagt ttgagtttct atagtattca gtgataaact tccattttct
     8581 ttgagcaaca tggatataag tacttgttat gtagtatgga tatgggcttt gtgaatccaa
     8641 gtaagactga taagcttgta taccaaaata tgctccacca attattgcac cccatggacc
     8701 ccccaataaa gcacctatcc taccaatcat ataactgatt ccagcaccag tcatgaagtt
     8761 agcgaatgtg ttagcttgtt tattcccatg tattgtgttg acgtaattcc aaacattagg
     8821 atcgtatgat ctaaaagata tatttaggtc gatttcattc ttttgataag ccatataaaa
     8881 tgccccattg atatagacgc cgtcagcacg tcgttcaata gtgtctacac ttccatctgg
     8941 attgacaacc tcaagaactt catcgcttaa aatatttact tgcgtatctc cgaaccgcac
     9001 tgatgagcca ttctcaaact gagcctcacc agatacaact ttagagtttg ccgataagct
     9061 atcatcagca aaaacaaaca agcgacgggg aaatgctaga catacagaaa acagacataa
     9121 ctagcaaaca catgcattta aacatcttag acataacgga aactcctttg tatttttgat
     9181 ttttttcaac ttttattata caataaaacc aaataaaaag aaagcggtaa caatatgctt
     9241 aatgcgaaaa ttttttatat atttttatgt ttgatcgtta tcgaaactac aggcttgttg
     9301 ttgttgaaaa gaggtctcga aatgggttat ttagacacag aagctattat cctcgcagtt
     9361 ttttcatttg ctttttacaa cctatgttca ttcgcttggg tctgctctac aataaaaaac
     9421 aataaaaaat aaatagacgt attttcaaaa aaaaaaaaat gcatatttat cttagcaaaa
     9481 cgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat ctgaggtgta
     9541 agtcctcggt gggtacctgc taccggtgct cccaatagtg attcccaagc ctgactatcg
     9601 tgaggtagcg gattaaaacg gtctggggat agaccgtttt aagtctgacg ctggaaataa
     9661 gaatcgtcag aggaagggat agcgaaatcg tggctctacg aataggaacg tgataataag
     9721 gcgtatatag cggataaggg gcctcaaact ctaaagttca aaaaggtagt cgtagcctat
     9781 atgtgtaaat cacgagagta attgaattcg gactaaggtc tatgtgaaaa agataaatct
     9841 tcctagagtc taaagactct gcgtcagatt tcctattttc attgtaacct tttaacgtcc
     9901 tcatatcttg tataaacgag gaaagatgta cgacttatcc cgtgaggttt catgagcgct
     9961 gaaagcgtag taacaacgaa tcatgagaag tcagccgagc ccatagtagt gaggaaactt
    10021 ctgtagtgga agtggagcga aggggtgaat actcaaacag tctggggaga gactgtttga
    10081 ggtctgtcgc tagaaagaga aaacgacaga tcgaagtaat cctacttcac ttgtgtctgt
    10141 aaaacgaacg gtctgataga actggactct gtcacgtatt gactagatga aggttcacca
    10201 atataagatg tccctcaggc accaaaacaa gaaaggaata ggcacatgtc aaaattgcta
    10261 gataagatat tatcacgcga caatatgctt gaagcctaca atcaagtaaa atctaataaa
    10321 ggctcagctg ggattgatgg aatgactatc gaagagatgg atggctatct cagacaaaac
    10381 tggcgcctga ctaaggaact gataaaacag agaaaatata agcctcaacc agttcttaga
    10441 gttgagattc ccaaaccaaa cggaggcatc cgccaactag gaattccaac agttatggat
    10501 agaatgattc aacaggccat tgttcaagtt attagcccta tttgtgaacc ccatttctca
    10561 gatacgagct atggattcag accaaatagg tcatgtgaaa aagccatcat gaagctctta
    10621 gagtacttaa atgacggcta tgagtggata gtggacatag acctagagaa atttttcgat
    10681 acagttcctc aagatagatt gatgtcctta gtacataaca ttatcgaaga cggagatacg
    10741 gaatccttga ttcgtaagta tcttcattca ggtgttatca ttaatggtca acgttataaa
    10801 acactagttg gtacaccaca gggaggaaat ttatctcctc tcttatccaa tatcatgctt
    10861 aatgaattgg acaaggaatt agaaaagagg ggacttcgat ttgtgcgcta cgcagatgat
    10921 tgtgtgatta cggtcggaag cgaggcagcc tctaagcgtg tgatgtattc agtcagtcgt
    10981 tttattgaga aacggctagg tttgaaagta aacatgacca agactaagat taccagacca
    11041 agagagttga aatatctagg ttttgggttc tggaaatcat cagatggttg gaaaagccgt
    11101 ccacatcaag atagtgttcg gagatttaag tttaaattga agaaactaac acagaggaaa
    11161 tggagtatag acctaacaag acgtattgag caactgaatt tgtctattcg aggatggata
    11221 aactatttct cattgggaaa tatgaaaagt atagtcgcca gcatagatga gcgcttgcgt
    11281 actcgcctac gagtgattat ctggaagcaa tggaagaaga aatcgagacg attatgggga
    11341 ttgcttaagt taggagttcc taaatggata gcagataagg tatctggctg gggcgaccat
    11401 tatcaattag tagctcagaa gtcggtactt aaacgtgcta tatcaaaacc agtcctggaa
    11461 aaacgtggac tggtttcgtg tttggattat taccttgaac gacatgcgtt aaaagttagt
    11521 tgaaccgccg tatgccgaac ggcacgtacg gtggtgtgag aggggctaga gattatcccc
    11581 tactcgatta actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc
    11641 tgagacgacg atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag
    11701 aaaagcttag agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc
    11761 tctttttcga ttgaagatgt aattattcta ctaactaact aacttcttag tactagccaa
    11821 caacgataat cataattcct cctaaaatta ggaataataa aggcaatagt ttttgttttt
    11881 tcatgtaaaa aacctcactt ttgttttctg ctattttatg ctaaaatatt aaaaatcaaa
    11941 tttaattcca aagtttgtaa ctaaaggggg agcgctacat gtctaattca tttgtcaagt
    12001 tgttagtctc tcaattattt gcaaatttag cagatatttt ctttagagta acaatcattg
    12061 ctaacatata cattatttca aaatcagtaa ttgccacatc actagttcct atcttaatag
    12121 gaatatcctc ttttgttgcg agtcttttag ttccgttggt tactaaaagg ttagcgctaa
    12181 atagggtttt atctttatct caatttggaa agactatatt attggcgata ctggtaggaa
    12241 tgtttaccgt aatgcaatcc gtagcgcctt tggtgaccta tctatttgtt gttgcaattt
    12301 ccatactaga tggttttgca gcacccgttt cctatgctat tgtgccacgc tatgcgaccg
    12361 atttgggtaa ggctaattca gccttatcaa tgactggtga agctgttcaa ttgataggtt
    12421 ggggattagg tggactcttg tttgcaacaa ttggtctgtt acctaccacg tgtatcaatt
    12481 tagtcttgta tatcatttct agctttctga tgttatttct tcctaacgct gaagtggagg
    12541 tgttagagtc agaaactaat cttgaaattt tgctcaaagg ttggaagtta gttgctagaa
    12601 atcctagatt aagacttttt gtatcagcaa atttattgga aattttttca aatacgattt
    12661 gggtttcttc cattatactt gtttttgtaa cggagttatt aaataaaacg gaaagttact
    12721 ggggatattc taatacagca tactctattg gtattataat tagtggctta attgctttta
    12781 ggctatctga aaagttcctt gctgctaaat gggaaagtat tctttttcct cttgtagcta
    12841 tggcaatagt gacactgact attctatatt ttccaaacgc acagatgttt ttattatttt
    12901 cagctttagt tggtatgtta tcgcaactaa aagaagttcc tgaaagtgta tttcttcagg
    12961 aaacagtaga ggaaaatcat ttagttaatg tctattccgt tcttgaagtg atttctacat
    13021 tagcattttc agtatttgtt ttgctaatga gctatattac tgagagtttt ggtattagca
    13081 tcagtttttg gctatcagcc atttgtctga tgatagaagc tattttaatt tatatcagac
    13141 gagattattt taaatgagag agtggttaaa aagtctttaa aaatcagaaa agcgcatagt
    13201 atcaggtgtt gaaaaaactt gatattgtgt gttttattat gggaagattt acttcattgt
    13261 ctcctgaaat ggagttttga agcaggatca ctctatttga aaatatacat agaaaaactg
    13321 tataatcctt aaaataagct gaaatctatt ggaaacatac ggtaaacaat tgaaaaggta
    13381 ctatataaag tggtacaatg gtagaaaaat aagctagtaa gaatcactct tattttagcg
    13441 aaaaattaca gaaatgaatg gtttttcttg atgaaacaga gaaaagaatt gtacctcttt
    13501 cttggtcgga cagccttgta ttttcttatc tttctagggc tgctttactt ctttagctat
    13561 cttggtcagg gtcaaggaag ctttatctat aatgaatttt aacttgaagg agaatcccta
    13621 ttgtgtcaaa taaaccaata gcagatatga ttgaaaccat tgagcatttt gctcagacac
    13681 agcctagcta tcctgtctat aatgttttgg ggcaggaaca cacttatggc gatttaaagg
    13741 ctgattcgga tagtttggct gcagtcattg accaactagg cttgcctgag aagtctcctg
    13801 tggttgtttt tggtggccaa gaatatgaaa tgttggcaac ctttgtagcg ctgactaagt
    13861 caggtcatgc ctacattcca attgatagcc attcggcctt ggagcgagtt tcagctattt
    13921 tagaagtagc agagccaagt ttgattattg ccatttcagc ctttcccttg gagcaggttt
    13981 ctacaccaat gataaatcta gctcaggttc aagaagcctt tgcccaaggg aacaactatg
    14041 aaatcacgca tccagtcaag ggagatgata attactacat tatctttact tctggtacga
    14101 ctggtaagcc taagggagtg cagatttcac atgataatct cctcagcttt acaaactgga
    14161 tgattacgga taaggaattt gcgacaccga gtcgtccgca aatgctggca cagccacctt
    14221 attcttttga cttgtctgtc atgtattggg caccgacctt ggcacttggt ggtacgcttt
    14281 tcactcttcc ttcagtcatc actcaggact tcaagcaact ctttgcggct atcttttcat
    14341 taccaatcgc tatctggaca tcaacaccat cctttgcaga tatggccatg ttgtctgaat
    14401 acttcaacag tgagaaaatg cctggagtca cgcatttcta ctttgatggt gaagaattga
    14461 cggtcaaaac agctcaaaaa ctgcgcgagc gtttcccaaa tgcccgtatc atcaatgctt
    14521 acggcccaac agaagcgaca gtagctctct cagcagttgc cgtgacagac gagatgttag
    14581 cgactctcaa acgcctacca atcggctata ccaaggctga ttctccaacc tttatcattg
    14641 acgaggaagg aaataaactg ccaaatggcg aacagggaga aatcattgtt tctgggccag
    14701 ctgtttcaaa aggttatatg aacaatcctg aaaaaacagc agaagccttc tttgagtttg
    14761 aaggtctgcc agcctatcac acaggcgatg tgggaaccat gacagatgag ggcttgcttc
    14821 tctacggcgg acgcatggac ttccagatta agtttaacgg ttaccgcatt gagttagaag
    14881 atgtctctca aagcctcaac aagtctcgct ttatcgaatc tgctgtcgca gtaccgcgct
    14941 ataacaagga ccacaaggta caaaatctat tggcttatgt catcttaaaa gacggtgttc
    15001 gtgagcagtt tgagcgagat atcgatatta ccaaggccat caaggaagac ctgacagaca
    15061 tcatgatgtc ctacatgatg ccatctaaat tcctttaccg agacagtttg ccactaactc
    15121 caaatggaaa gattgacatc aaaggattga ttaacgaggt gaataagaga tgatggagtt
    15181 ttttcaacag cttcctcatt tagagccata tggcaatcct cagtattttg tttatgtgat
    15241 tgctgcaacc ttgcccatct ttataggcct ctttttcaag aaacgctttg cctggtatga
    15301 agtgttggta agtctcttct ttattgtcac catgttggtg ggtggaaaga ccaatcaact
    15361 agctgccttg ggtatttacc tttgctggga aatattgctc ctgcttttct acaagcatta
    15421 tcgaaaaagc aaggatggca agtgggtctt ctacttagtt agttttctgt ccctacttcc
    15481 gattatcttt gtcaaggtgc aaccagctat caatggaacg cagtctttgc ttgggttctt
    15541 gggaatttct tacctgacct ttcgttcggt tgggattatc atcgagctga gagatggagt
    15601 gattaaggat tttaccctct gggaattcct ccgtttcctt ctcttcatgc caactttctc
    15661 gagtggtcca atcgatcgct ttaagcgatt taatgaaaat tatcaggcca ttcctgagcg
    15721 agatgagttg atggatatgc tggatgaatc tgtccgctat atcatgcggg gctttttgta
    15781 taagtttatc ctagctcatg ttttaggaga gaccttacta cctcctctga agaatttagc
    15841 cttgcagtca ggtggcttct ttaatcttta tgccttggca gttatgtata cttttggtct
    15901 ggagctcttc tttgactttg caggttattc tatgtttgct ttggccatct caaacttgat
    15961 gggaatccgt agccctatca actttaacaa gcccttttta tcaagggatt taaaggagtt
    16021 ttggaatcgc tggcatatga gtctgtcctt ctggttccgt gactttgtct ttatgcgaat
    16081 ggtgatggtg ttaaccagaa agaaagtctt taaaaatcgt aatgtaacct caagcatggc
    16141 ctacattgta aatatgctga ttatgggatt ttggcatggc gtgacctggt actatatcgc
    16201 ctatggactc tttcatggat taggcttggt catcaatgat gcctgggttc gcaagaaaaa
    16261 aacgctcaat aaggaacgga aaaaagcagg gaaggctgcc ctacctgaga atcgctggat
    16321 tcagttgctt ggtatggttg tcactttcca tgttgtcatg ttgtcattct taatcttttc
    16381 tggattcttg aataatctat ggtttaaaaa ataaaaggaa ataaaatatg gatatcaaat
    16441 cagaagttat cgaaattatt gatgagttgt ttatggaaga tgtttctgac atgatggatg
    16501 aagatctttt tgatgcaggt gtcttggata gtatgggaac ggttgagttg attgtggaga
    16561 ttgagaaccg ttttgacatt cgtgtccctg taatagagtt tggtcgtgac gactggaata
    16621 cagctaataa aatcatagct ggtattgtgg agctacaaaa tgcttaaacg cttatggatg
    16681 atcttcggac cggtcttgat cgctggtttg ttggtttttc tgctcatttt cttttatcct
    16741 actgagatgc atcataatct aggagctgaa aagcgttcag cggtggctac tactatcgat
    16801 agttttaagg agcgaagtca aaaagtcaga gcactatctg atccaaatgt gcgttttgtt
    16861 cccttctttg gctctagtga atggcttcgt tttgacggtg ctcatcctgc ggtattagct
    16921 gagaaataca atcgttccta ccgtccttat cttttaggac aggggggagc tgcatcgctt
    16981 aaccaatatt ttggaatgca acagatgtta ccacagctgg agaataaaca agttgtgtat
    17041 gttatctcac ctcagtggtt cagtaaaaat ggctatgatc cagcagcctt ccagcagtat
    17101 tttaatggag accagttgac tagttttctg aaacatcaat ctggggatca ggctagtcaa
    17161 tatgcagcga ctcgcttact gcaacagttc ccaaacgtag ctatgaagga cctggttcag
    17221 aagttggcaa gtaaagaaga attgtcgaca gcagataatg aaatgattga attattggct
    17281 cgttttaatg aacgccaagc ctcctttttt ggtcagtttt cggttagagg ctatgttaac
    17341 tacgataagc atgtagctaa gtatttaaaa atcttgccag accagttttc ttatcaagca
    17401 atagaagatg ttgtcaaagc agatgctgaa aaaaatactt ccaataatga gatgggaatg
    17461 gaaaattatt tctataatga gcagatcaag aaggatttga agaaattaaa ggattctcag
    17521 aaaagcttta cctatctcaa gtcgccagag tataatgact tgcagttggt tttaacacag
    17581 ttttctaaat ctaaggtaaa cccgattttt atcattccac ctgttaataa aaaatggatg
    17641 gactatgctg gtctacgaga ggatatgtac caacaaacgg tgcagaagat tcgctaccag
    17701 ttagaaagtc aaggttttac caatatagca gatttttcta aggacggcgg ggagcctttc
    17761 tttatgaagg acaccattca ccttggttgg ttgggttggt tggcttttga caaggcagtt
    17821 gatcctttcc tatccaatcc cacaccagct ccgacttacc atctgaatga gcgctttttc
    17881 agcaaagatt gggcgactta tgatggagat gtcaaagaat ttcaatagat aatataatat
    17941 agaagagttc aagaatgaaa ctagttttca cgttttttct tgactctttt tttgcttgtg
    18001 atataattaa ctggtaaaca aaatgtcaaa gaatagtatt tttctcttaa aaaagagaag
    18061 tctaaaagga aaggagtcag atatgagaca gctagcaaag gatatcaatg cttttttgaa
    18121 tgaggtgatt ttgcaggcgg aaaatcagca tgaaatccta ataggtcatt gcactagcga
    18181 ggtggccctg accaatactc aggagcatat ccttatgctc ttgtcagagg aatctttaac
    18241 aaattcagaa ttggcccgtc gtctcaatgt cagtcaggcg gcagttacca aggccattaa
    18301 gtctttggtc aaggaaggga tgttggaaac atctaaagat tctaaagatg cgcgtgtgat
    18361 tttttatcag ttgactgact tggctcgtcc aatcgctgag gagcaccacc atcaccatga
    18421 gcatacactt ttaacctatg aacaagtggc gactcagttt actccaaatg aacaaaaagt
    18481 gattcagcgg tttttgactg ctttagtagg agaaatcaaa taatgagata tattacggta
    18541 gaggatttgt ccttctatta tgataaggag cctgttcttg aacatatcaa ttattgtgtt
    18601 gatagtgggg aatttgttac cttgactggg gaaaatggag cggctaagac gacgctcatc
    18661 aaggctagtc ttggaattct gcaaccacgc attggaaagg tggctatttc aaagacaaat
    18721 acgcaaggta agaaattgag aatagcctat cttcctcaac aaattgccag ttttaatgct
    18781 ggttttccaa gtacggtcta tgaatttgtc aagtcgggtc gctatccgag aaaaggctgg
    18841 ttccgtcgtt tgaatgctca tgatgaggag catatcaagg ctagtctgga ctcagttggc
    18901 atgtgggaac atcgagacaa acgcttgggg tctctatctg ggggacaaaa gcagcgagcg
    18961 gtaattgcgc gtatgtttgc ttctgaccct gatgtgttta tcctagacga gccgacaacg
    19021 gggatggatg caggaagtaa aaatgaattt tacgaactca tgcaccatag cgcccatcat
    19081 catggcaagg ctgttttgat gattacccat gaccctgaag aagttaagga ttatgcggat
    19141 cgcaatattc atctagtccg taaccaagac tcgccatggc gttgtttcaa cgttcatgag
    19201 aatggccagg aggtgggcca tgcttagttt attatcttac gactttatac aacgcgcctt
    19261 tttggcggtt attgctatga gtcttttctc accggtattg ggaaccttcc tcatcttgcg
    19321 tcgtcagagt ttgatgagtg atacccttag ccacgtctca ctttcaggtg tagcctttgg
    19381 tctggttttg gggatttctc caactgtttc tactattgcc attgtcttga ttgcggcggt
    19441 ctttctggag tatctccgta cagtttacaa gagctttatg gaaatcggga cagctatcct
    19501 catgtcaaca ggtctggctg tttctctgat tgtcatgagc aagggtaaaa gctcgagttc
    19561 aatgagtttg gaccaatatc tctttggttc gatcgtgact atcagtgaag aacaggtcat
    19621 ttccctcttt gtcattgcgg cggttgtttt gattttgacc tttctctttc ttcgtcctat
    19681 gtatatctta acttttgacg aagatacggc ctttgtggat ggcttgccag ttcgtaccat
    19741 gtccattctt tttaacatgg tgacaggggt ggctattgcc cttatgattc ctgcagcagg
    19801 agctcttcta gtatcgacca ttatggtctt gccagctagt attgccctgc gtctggggaa
    19861 aaactttaaa tcggttatgc tgcttgccag tgcgattggc tttttgggaa tggtagcagg
    19921 actttacatt tcctactatg cagaaacacc tgcaagtgca agtattacca ttatttttgt
    19981 aactgtcttt atactaatca gtttagtaag acgttttatc aaataggaga cgaacgtgaa
    20041 aaaaattagc ttattactag ccagtctatg tgccttgttt ttagtggctt gttccaatca
    20101 aaaacaggca gatggtaaac tcaatatcgt gacaaccttt taccctgtct atgaatttac
    20161 caagcaagtc gcaggagata cggctaatgt agaactccta atcggtgctg ggacagaacc
    20221 tcatgaatac gaaccatctg ccaaggcagt tgccaaaatc caagatgcag ataccttcgt
    20281 ttatgaaaat gaaaacatgg aaacatgggt acctaaattg ctagatacct tggataagaa
    20341 aaaagtgaaa accatcaagg cgacaggcga tatgttgctc ttgccaggtg gcaaggaaga
    20401 agagggagac catgaccatg gagaagaagg tcatcaccat gagtttgacc cccatgtttg
    20461 gttatcacca gttcgtgcca ttaaactagt agagcacatc cgcgacagct tgtcagcaga
    20521 ttatcctgat aaaaaagaga cctttgagaa gaatgcagct gcctatatcg aaaaattgca
    20581 agccttggat aaggcttacg cagaaggctt gtctcaagca aaacaaaaga gctttgtgac
    20641 tcaacacgca gcctttaact atcttgcctt ggactatgga ctcaaacaag tcgcaatctc
    20701 aggactttct ccagatgcag agccatcagc tgctcgcttg gcagaattga cagagtatgt
    20761 caagaaaaat aaaatcgcct atatctattt tgaagaaaat gcctcacaag cccttgctaa
    20821 cacactttca aaagaagcag gtgtcaaaac tgatgtcctc aatcctttag aaagtctgac
    20881 agaagaggac accaaggctg gagaaaatta catctctatc atggagaaaa acctcaaggc
    20941 tttgaaacaa acaacagacc aagaaggccc agcgatcgag cctgaaaagg cagaggatac
    21001 caagacagtc caaaatggtt acttcgagga tgcagctgtc aaggaccgca ccttgagtga
    21061 ctatgcaggt aactggcaat cagtttatcc tttccttgaa gacggcacgt ttgaccaagt
    21121 ctttgactac aaggctaagt tgactggtaa gatgacccag gctgagtaca aggcttatta
    21181 tacaaaaggc tatcagacag atgtgactaa gattaacatt actgataata ctatggaatt
    21241 tgttcaaggt ggacaaagca agaaatatac ttacaagtat gtcggtaaga aaattttgac
    21301 ttacaagaaa ggcaatcgtg gcgtgcgttt cctctttgaa gccacagatg ctgacgctgg
    21361 acaattcaag tatgttcagt ttagtgacca caatgttgcc ccagttaagg cagaacattt
    21421 ccatatcttt tttggaggta caagccaaga agctctattt gaagaaatgg ataattggcc
    21481 aacctactac ccagataacc tatctggcca agaaatcgct caagaaatgt tggcgcatta
    21541 atgagaaatc gactagttca taagagctag tcggtttttg ggtactagat ggctaacttc
    21601 attatagact tttcagaact aaggaacttt aaaaaaataa ataaaactct tgaaatatct
    21661 ggacttatat gctagaatgt agttagtgta taaggttcat tagaacacca aagcccctaa
    21721 ctagtgccat agttaagggc ttttttgatg tatcttagcg atttaacggg tgtttatagg
    21781 ctagtcagtc ggtctacttc ttaccatcta gccatttgca gacgaaatac aagataattc
    21841 cagctataac atctgctata atagtaagag caagctctgg tataaggctc attagtttca
    21901 cctcctctca cgaacccata ggaacgtaat cggtaaccga tgacaaaagt attatatcac
    21961 actaaattta gatcatcaac ctcacttaat gcttgaacta ttgtagatta tatgctaaaa
    22021 tgtagttaat tgataaggtt cattagaaca ccaaagcccc taactatggc cgtagttaag
    22081 ggcttttttg acgtatctta gcgatttaat gggtgtttat aggctagtca gtcggtctac
    22141 tccttactat ctagccatct gcagacgaaa tacaagataa ttccagctat aacatccgct
    22201 ataatagtaa gagcgagctc tatgataagg ctcattagtt tcacctcctc tcacgaaccc
    22261 ataggaacgt aatcggtaac cgatgacaaa aatagtatac cacaatacat ttagatcatc
    22321 aaggtcactt aattcttgaa atatcagatc taagagaaaa atctttaaaa tcagaaaaac
    22381 gcataatatc aggtgtgcaa aaacttgata ctatgcgttt tattgtggga aggtttactc
    22441 cattttctcc tgaaattgag tttttgtcca gcctctgttt ttagggttgc taagaaaata
    22501 atgtcatgtg gtgaatattt gtaaatcagt cagcagacag aacgaatact cttcgaaaat
    22561 ctcttcacat catgtcagct tcgtcttgcc gtgtccatgg gggacttgac ttcatcagtt
    22621 ttcaaatctg tactgtgagc aagttgagac tagcttccta tttgattttc attgaatatc
    22681 agaaacccat tctccatcaa ataattcgac tgcgtctaat aatttttgat ctggcaaggt
    22741 gtcagaaata aaggttgtgt atttggagag gggattaatt ttaaaaaatc cagtcttgta
    22801 aaatttagaa ctatcaatca gtaagatggt ttcatgggct ttgtcaataa tattcttttt
    22861 tgaaatagct tggctgagag aagcttcata aacatattgg tcatcaatac ctcttgctga
    22921 acaaaatgct aaatcgatat taaaatgatc taataaagaa ttttccttat catagttgac
    22981 cacggaacag gattgatgtt tgacctcgcc agatgtgata aagattttgg agctatcttt
    23041 aacagtttca gatagggttt gtgcagtatg taaaccattt gtaaaaataa tcaaattatc
    23101 aagttcagaa agatagggac aaagttcgta gacagtcgta ctggaatcca gataaacaca
    23161 cataccagac cgaataaagt ctttagcgag actagcgatt agtctttttt gcctagtact
    23221 ttctccttcc cgtatttgat gagaaagttc aattgtgttc atagaggaca gggtcacgta
    23281 tccgtgcttt cttttgataa gaccttgatt ttctaagaaa attaaatcac gacgtaaggt
    23341 acttgtgctg gagaaagtga tttctgccag ctcttttacg gcaattcttt ttttcttttt
    23401 gataatttca atcaattcaa gtacacgttc atcttttatc ataagctcct cctaatttat
    23461 catttcaact atattatagc acaaattgga ggaatttgaa ttatttttat gaatattggg
    23521 ttaacatttg aacattattc aagtaagcgt tcacatattg aaaaaataaa atgtggggat
    23581 tataataaag ttaatcaagg acgaagagag aagaaaaatg gaagcggttt tagcaataga
    23641 tttaggtgcg acttctggaa gagcaatcgt tggttacctt tctgaaaata aactagtaat
    23701 ggaagaaata aatcgctttt ctaatctacc tattagagta aaagggcatt tatcttggga
    23761 tattgacttt ctactagcta aaattcttga aagtatccgc ttggctaata ctagttacaa
    23821 gattttatct atcggtattg acacatgggg agttgatttt ggactgattg ataatgaagg
    23881 taagctgtta tcacaacctg ttcattatcg tgatgaaaga acaaagggag tgttaaagga
    23941 aatatctgaa atgactgaat tagaaaaact gtattcagag acaggaaatc agattatgga
    24001 gataaatacc ttgtttcaac tctttaaggc acgtcaagaa tctcctgact ctttctataa
    24061 gaccaataag attcttttaa tgccagattt gtttaattat ctcttgacag gtaagtttgc
    24121 tacagaaaaa agcattgctt caacaactca attatttgat cctaggagtc aaaattggaa
    24181 tcagaatatc ttaaaactat ttgaattgga ttcatcttta cttcctgaaa ttgtttcaga
    24241 gggaaatgtt cttggaagga taaaaaagga gtatggttta ggcgatattc ctgttgtgaa
    24301 tgtttgtagt catgatacag caagtgcgat tgtctcagta cctaagacag aaggtagttt
    24361 atttatttca tcaggtactt ggtctttggt tggagtggaa cttacttcac cgattcttac
    24421 taccgaatcc ttcagttatg gatttacaaa tgaagtcggt aaagatggag agattacatt
    24481 tctgaagaat tgtacagggt tgtggatcat agaggaacta agacgttcat ttgaacgaag
    24541 agggaaagcc tattcttttg atgatattag gacaatggtg gagaaagaaa aagaaaatct
    24601 tcctctgatt gatactgaat caactgaatt tgcaacagaa tctgatatgc acaagacttt
    24661 gacagaatat ctagcttatc atcatgaaac tagagagtgg acagatggac aactatttaa
    24721 gattgtttat gaaagcctag ctgaaacgta taggaaagcg atagagttat tagaagaact
    24781 aactcataag gtttataaga ggatatatgt gattggagga ggtgctagag ccagttactt
    24841 taaccaaatg attgctgata gaactggtaa agaggttctt acaggttcga ctgagggtac
    24901 agctgtgggg aatattgttg tgcagctcat agctatggga caattaaaag ggatggaaga
    24961 agctcaccat gttattgagg agttcctaca attagagagt tattactccc aaaagaatta
    25021 aaaagattga gagtttgtaa atttgcctcc ctcccccttc ttagcttttg tgcaggaagg
    25081 ggggataatt ggtgaattga aaaatattta gtgttttgat atgaggagga caaggatgtc
    25141 agatgtaaaa caagaattaa ttaaatatgg taagaagcta gtagaaacag atttgacgaa
    25201 aggaacaggt gggaatctca gcgttttcga tcgtgaaaaa caattgatgg caattacccc
    25261 gtcgggtatt gatttctttg aaatcaaaga atccgatatt gtagtgatgg atattaatgg
    25321 aaatgttgta gagggagaac gcttgccatc tagcgaatgg tatatgcatt tgattcaata
    25381 tcaaactcgt gatgatatcg atgcaattat ccatgctcat acaacttatg caacagtatt
    25441 agcttgtctc agagaaccac ttccagcgag tcattatatg attgcagtgg cagggaaaga
    25501 tgttcgggta gctgagtatg caacatatgg tacgaaagaa ttggctgtga atgcagctaa
    25561 agcaatggaa ggtcgtagag cagttttact agcgaatcat ggaattttag caggtgcaca
    25621 aaatttattg aatgcattta atattgttga agaagttgaa tattgtgcaa aaatttattg
    25681 tttagctaag aattttggag agccagtagt tcttcctgat gaggagatgg aattgatggc
    25741 agaaaaattt aaaacatacg gtcagagaaa atagggagga tattaatgtt aaaacatata
    25801 ccgaaaaata tttctccaga tttattgaag actttaatgg aaatgggaca tggagatgaa
    25861 atagtattag ctgacgcgaa ttatccttct gcctcatgtg caaataagct aattcgttgt
    25921 gatggtgtaa atattccaga attattagat tccattctgt atttaatgcc attagatagt
    25981 tacgtcgata gttcaattca gtttatgaac gttgtttcgg gtgatgatat tcctaagata
    26041 tggggtacct atagacaaat gattgaaggt catggtacag atcttaaaac gattacttat
    26101 cttagaagag aagactttta tgaacgtagt aagaaagctt atgctattgt tgctacagga
    26161 gaaacttcac tttatgctaa tattatcctt aagaaaggag tagttgttga aagagaaaat
    26221 gtttaataga ggaattttag ttgccagtca tggtaatttt gctagcggag ctctcatgac
    26281 cgcagaaatg tttgttggtg agacaacaaa tgatagagtt aggacattag gtttgatgcc
    26341 tggagagaat attgtagagt ttgaacatta ttttaaaaat caagtaaatg aactgttaga
    26401 ctcaaatcaa gaggttatcg ttttgactga cttgattgga ggaagtccta ataatgtggc
    26461 tttgtcacgg tttttaaatt tggattcagt tgatattgta acagggttta atatccctct
    26521 cctagtggaa ttaatatcaa gttatgattc aaaaatcaat ttagaagaaa ttgttcacaa
    26581 tgctcaaaat agtttgttta atgttaaaca acaacttaac gtagaggagg aagaggattt
    26641 atgtctatag agtttgttcg tattgatgac cgtctggtac atggtcaagt tgtcactacg
    26701 tggctaaaaa agtatgatat tgagcaagtt atcattgtta atgatcgcat ctcagaagat
    26761 aaaacacgac aatctatttt aaagatttct gcaccggtag gtttaaaaat tgttttcttt
    26821 agtgtaaaac ggtttgtgga agttttaaac tctgtgccaa taaaaaagag aacaatgctg
    26881 atatatacaa atccaaaaga tgtgtatgat tctattgaag gaaatttaaa attggagtac
    26941 ctcaatgtag gacagatgag taaaacggag gaaaatgaaa aggtaacggg aggtgtagct
    27001 ctaggtgaag aagacaaata ttattttaag aaaatagttg ataagggaac gagagttgaa
    27061 attcaaatgg ttcctaatga taaagttaca atgttggaaa aatttttata aaaataattt
    27121 aaggaggtac agtatatgct attcacacaa gcattactgg tgacattagt tgggattatt
    27181 gccactattg actataatgg accgttattt atgattcacc gtccgttagt tacaagtgca
    27241 atggttggct tagtcttagg agatttcacc caaggtgttc ttattggttc agctcttgaa
    27301 ttaacttggc tcggtgtaac aggtattgga ggttacactc caccagatac tatttcaggt
    27361 gcgattattg gtactgcatt tggtattttg tctggtcaag gagaaactgc tggtatcgct
    27421 atagcagttc caattgcagt tgctactcaa cagttggatg ttcttgcaaa aactttagat
    27481 gtttattttg tgaaaaaagc tgataatgat gctaaaaacg gagattattc aaagatcggt
    27541 ttttatcatt attcaagttt ggttttaatc actttattta aaattgtacc aattttccta
    27601 gctattatgc ttggagggga atatgtggca gacttgtttg ctaaggttcc accaatcgtt
    27661 atgcagggac ttaactctgc aggtgcttta ctaccttcaa ttggttttgg tatgctttta
    27721 aatatgatgc tcaagaaaaa tatgtgggta ttcttgttga ttggattcat ttgttctgtg
    27781 tatggaggaa tgtcaaccat tgggatctca ctagttggta ttgcggtagc atacttctac
    27841 gatatgattg gaagtaaacc acaagaaaca acttcaagta gtgatgttga ggaggatctt
    27901 gatctatgat gaataataaa gtaactaaag ttgaacttaa aaaagttttc aaacgaagtt
    27961 ttatgtatgg ttcttcatgg aactatgaga gaatgcagaa cctaggtttt ctatatacaa
    28021 ttcttccagt attgaaaaaa ctatacccag acaaagattc agcttctcct gcaatgaaac
    28081 gtcaccttga gtttttcaat actcatcaaa cagcggcacc atttattctt ggagttactt
    28141 ccgctatgga agaacaagaa ggaaatgaag gtgcagcttc aattactggt attaaagttg
    28201 gcttgatggg gccactggct ggtctaggag atagtttgtt ctggctgaca ctagttccta
    28261 tctgttttag tattggtgcg tcttattcta aagacggcgg tgctttaggt atctttatcg
    28321 ccttaatatt gtttaatatt attaatattc ctgttaaata tttcggtttg aaatatgggt
    28381 atactaaggg ttctagtctt atccaagaaa ataatacaaa aggaacattg aatcgcgtta
    28441 cgagtatggc gacagcatta gggctagtac tagtgggtgg tttgattcca tcaatggttg
    28501 gtattaattt tggattagaa tttaagcagg gggaacttgt tatttctgtt caagaaatga
    28561 ttacaaaatt aattccagga tttatcccta tggctttgac tttattaatg tgtaaattaa
    28621 ttagaaaagg aaagaatccg gttgtactaa tctttagtgt tatggctatt ggagttatcc
    28681 tagttgtttt aggaattttg aagtagtaga aagtgtggag gtggtatttg ggatatcacc
    28741 tccattttgg aagagaggta aagagtgaaa ttatggtata agaaagctgc cgcaaattgg
    28801 aatgaagcct tgccgattgg gaacggtcat ttaggtggta tgatttatgg ttcagctaca
    28861 aaagaatgta ttcaactaaa cgatgagact atttggtata gaggaaagtc agatagaaat
    28921 aatccagact cactattgca tcttaaaaaa attcgggaat atcttttaga tggagaaatt
    28981 cagaaagccg aagaattgat aaagttaaca atgtttgcta ccccaagaga tcaaagccac
    29041 tatgaattac ttggggaact ttgcattgag catatagata ttcagtcttg tgctctttca
    29101 ttgtatgaaa gagagctaga tttagataca gctatttcta atgttgtgtt tgagcctaat
    29161 agttgtaatt tacaaataaa aagagaatat tttacgagtt ttaataagaa tattttatgt
    29221 tgccgtatag tgtcatcagt tcaaaacaca ttaaatttaa acattaattt gggtagaaat
    29281 aaacggttta atgacgaagt atctaaactg gattcaagta caattttaat gtcggcctct
    29341 gctggaggta gaaaaggtgt tcagtttaaa gtagtatgtc attctaaggt tacggatggt
    29401 gaagtaagtg tattgggaga gacaatagtt attcggaatg ctacagaggt atttctttat
    29461 ctcaaatcaa tgacggatta ttggggaaat atagatattt cttctcttca gggagaattt
    29521 agtagtattg attactttac agaaaaagat gaacatgtaa aaaaatatca ggagcaattt
    29581 aatagagttg attttaaact agactatagt aaaggttgtc ttagcattcc aacgaatcta
    29641 cttcttgaaa acactaaaaa gtatagtaac tacttgacta acttgttatt tcattatgga
    29701 agatatctgt taatatcgtc tagtcaaccg aatggtttac ctgccaatct tcaaggaata
    29761 tggtgtgatg aattaaatcc aatttggggt tctaaatata cgattaatat taatactcaa
    29821 atgaattatt ggatggtagg tccatgtgat ttaccagaag tagaatatcc attatttgat
    29881 atgctcgaaa gaatgagaga accgggaaga ctaaccgcta agaaaatgta tggagctaga
    29941 ggttttacag cacatcataa tacggatggt tttggcgata cggctcccca atctcatgcc
    30001 atgggggctg caatttgggt attaactatt ccatggttat gtactcatat ttgggaacac
    30061 tatttatatt tccaagatga gcgtattctt acggaacatt ttgaaatgat aaaagaagca
    30121 tttcttttct ttgaagatta tttatttgag gtggatggct acttgatgac aggtccaagt
    30181 gtctcaccgg aaaataaata tcgcttaaaa aatggtattg aaggaaatgc ttgtctatca
    30241 tctacaattg ataatcaaat tttaagatat ttttgtgatt catgcattgg aattgcaaaa
    30301 caattaggag acaattcgga ttttattagt cgtgtgaagg agttaaaaaa gaaattacct
    30361 agaacaaaaa taggtagtaa tgggcaaata caagaatggc tagaggatta tgaagaagta
    30421 gagcctggtc atagacacat ttcacctcta tttgggcttt atccttataa tgagattgat
    30481 attcataaaa ctccggaatt agcagaagca gctaaaatca ctatcaatag gagattatca
    30541 aacgctaact ttttatcttc acaggatagg gagcaagcga ttaataattg gttagtaagt
    30601 ggtttgcatg ctagtacaca aacaggttgg agtgctgcat ggctgattca tttttttgcg
    30661 agactatatc aaggtgaacc tgcttataac cagattaatg gtttgttaaa taatgcgact
    30721 cttggcaatt tatttcttga ccatccacca tttcaaattg atggtaattt aggtttggtg
    30781 agtggaattt gtgaattatt agtacagagc catcataatt ggttatcact aattccagct
    30841 ttaccttctg cttggtcaga aggagaagtg aaaggtttca gagtaagagg aggatataag
    30901 gtatcgtttg cttggaaaaa tggggatata acattcctaa aattggaagg aggaaacaaa
    30961 gatcaaaaag taagagtaag aatatatggc aaaaatactg atgtacaaaa tattgaattg
    31021 gtatttaatt cagaaaaaat tattgagtta aatttttagg tataagtcat gaataaagaa
    31081 aaaataaaaa gaaaattaat cacaatactg tttgtatgta ttgggatgtt atgttttgga
    31141 ttgttagcag gagttaaggc tgataatcgt gttcaaatga gaacgacgat taataatgaa
    31201 tcgccattgt tgctttctcc gttgtatggc aatgataatg gtaacggatt atggtggggg
    31261 aacacattga agggagcatg ggaagctatt cctgaagatg taaagccata tgcagcgatt
    31321 gaacttcatc ctgcaaaagt ctgtaaacca acaagttgta ttccacgaga tacgaaagaa
    31381 ttgagagaat ggtatgtcaa gatgttggag gaagctcaaa gtctaaacat tccagttttc
    31441 ttggttatta tgtcggctgg agagcgtaat acagttcctc cagagtggtt agatgaacaa
    31501 ttccaaaagt atagtgtgtt aaaaggtgtt ttaaatattg agaattattg gatttacaat
    31561 aaccagttag ctccgcatag tgctaaatat ttggaagttt gtgccaaata tggagcgcat
    31621 tttatctggc atgatcatga aaaatggttc tgggaaacta ttatgaatga tccgacattc
    31681 tttgaagcga gtcaaaaata tcataaaaat ttggtgttgg caactaaaaa tacgccaata
    31741 agagatgatg cgggtacaga ttctatcgtt agtggatttt ggttgagtgg cttatgtgat
    31801 aactggggct catcaacaga tacatggaaa tggtgggaaa aacattatac aaacacattt
    31861 gaaactggaa gagctaggga tatgagatcc tatgcatcgg aaccagaatc aatgattgct
    31921 atggaaatga tgaatgtata tactggggga ggcacagttt ataattttga atgtgccgcg
    31981 tatacattta tgacaaatga tgtaccaact ccagcattta ctaaaggtat tattcctttc
    32041 tttagacatg ctatacaaaa tccagctcca agtaaggaag aagttgtaaa tagaacaaaa
    32101 gctgtatttt ggaatggaga aggtaggatt agttcattaa acggatttta tcaaggactt
    32161 tattcgaatg atgaaacaat gcctttatat aataatggga aatatcatat tcttcctgta
    32221 atacatgaga aaattgataa ggaaaagatt tcatctatat tccctaatgc aaaaattttg
    32281 actaaaaata gtgaggaatt gtctagtaaa gtcaactatt taaactcgct ttatccaaaa
    32341 ctttatgaag gagatgggta tgctcagcgt gtaggtaatt cctggtatat ttataatagt
    32401 aatgctaata tcaataaaaa tcagcaagta atgttgccta tgtatactaa taatacaaag
    32461 tcgttatcgt tagatttgac gccacatact tacgctgttg ttaaagaaaa tccaaataat
    32521 ttacatattt tattgaacaa ttacaggaca gataagacag ctatgtgggc attatcagga
    32581 aattttgatg catcaaaaag ttggaagaaa gaagaattag agttagcgaa ctggataagc
    32641 aaaaattatt ccatcaatcc tgtagataat gactttagga caacaacact tacattaaaa
    32701 gggcatactg gtcataaacc tcagataaat ataagtggcg ataaaaatca ttatacttat
    32761 acagaaaatt gggatgagaa tacccatgtt tataccatta cggttaatca taatggaatg
    32821 gtagagatgt ctataaatac tgaagggaca ggcccagtcc ctttcccaac accagataaa
    32881 tttaatgatg gtaatttgaa tatagcatat gcaaaaccaa caacacaaag ttctgtagat
    32941 tacaatggag accctaatag agctgtggat ggtaacagaa atggtaattt taactctggt
    33001 tcggtaacac acactagggc agataatccc tcttggtggg aagtcgattt gaaaaaaatg
    33061 gataaagttg ggcttgttaa aatttataat cgcacagatg ctgagactca acgtctatct
    33121 aattttgatg tgattctata tgacaataat agaaacgaag ttgctaagaa acatgttaat
    33181 aatttgtcgg gtgaatctgt tagtctagat ttcaaagaaa aaggagcaag gtatattaaa
    33241 gttaaattac taacgagtgg agtgcctttg agtttagcag aagtagaggt ttttagagaa
    33301 tcagatggta agcaatctga agaggatata gataaaataa cagaagataa agtagtctct
    33361 acaaataagg tagctactca aagttcaacc aattatgagg gtgtagctgc tttagcagtt
    33421 gatggtaata aagatggaga ttacggacat cattcggtga ctcatactaa ggcagattct
    33481 aacgcttggt ggcaggtcga tctgggagaa gagtttacgg tttctaaagt tgatatttat
    33541 aatagaacag atgccgaacc tcagcgttta tctaattttg atgttatttt tctatcttca
    33601 tcaggagaag aagtttttag aagacatttt gataaagtag ttgatggttt gttatcttta
    33661 aaagtacctt ctgtaggggc taagctagtc aaaatagaat taaaatcagc agctattccg
    33721 ttaagtttag cggaagttga agtctatggt tcaaagagaa ctccgaagaa actttctaat
    33781 attgcattaa ccaaagaaac tcgacagagt tcaacggatt acaatggttt ttctcgtcta
    33841 gcagttgatg gaaataaaaa cggagattat gatcatcatt cagtgactca taccaaagga
    33901 aattctcctt catggtggga gatagattta gcacaaaccg aagaattaga aaagttaatt
    33961 atttataata gaacagatgc tgaaattcag agattatcaa attttgatat tattatatat
    34021 gattcaaata atcatgaagt ttttaaacaa catattgaca gtttagaaag caataatcta
    34081 tccatagact taaaagggct gaagggaaaa aaggttagaa tttctttgag aaacgcagga
    34141 attcctttaa gtttggcaga ggtagaggtt tatacttata agtaatttta aaaattatca
    34201 tcggtagtat gaaagaaaca gaaaaataag aggaaaatag tatgattcaa catccacgta
    34261 ttgggattcg tccgactatt gatggtcgtc gtcaaggtgt acgcgaatca cttgaagtac
    34321 aaacaatgaa catggctaaa agtgtggcag atttgatttc aagcacattg aaatatccag
    34381 atggggaacc tgtggaatgt gtgatttctc catctaccat tggtcgtgtt ccagaggttg
    34441 cagcttccca tgagttgttt aaaaaatcaa atgtttgcgc aacaattaca gttacaccat
    34501 gctggtgtta tggtagtgaa actatggata tgtctccaga tattcctcat gctatttggg
    34561 gatttaatgg gacagaacgc ccaggagctg tctatcttgc agctgtacta gcttcacatg
    34621 ctcaaaaagg gattccagcc tttgggattt atggtagaga cgtccaggaa gctagtgata
    34681 cagctattcc agaagatgtc aaagaaaaac ttttacgcta tgcgcgtgca gctcttgcaa
    34741 ctggcttgat gagagacact gcttacctat caatgggtag tgtttcgatg gggattggtg
    34801 gttctattgt aaatccagat ttcttccaag aatacttagg aatgcgaaat gaatcggtag
    34861 atatgacgga gttcacgcgc cgtattgacc gtggtattta tgacccagaa gagttcgaac
    34921 gtgctatggt ttgggtaaaa gaacatatca aagaaggtgt tgaccgaaat cgtgaagatt
    34981 tgattctttc taaagaagaa aaagaaaaac aatgggaatt tgttgtaaaa atgttcatga
    35041 ttggtcgaga tcttacgcag ggaaatcctc gtttagcaga gcttggtttt gaggaagaag
    35101 cagttggtca ccatgcttta gtagctggtt tccaaggtca acgtcagtgg acagaccatt
    35161 ttccaaatgg agattttatg gaaactttcc tcaatactca gtttgactgg aatggtattc
    35221 gaaaaccagt tgtatttgcg acagagaatg attcactaaa tggtgtgtct atgctcttta
    35281 attatctatt aacaaatact ccacaaatct ttgctgatgt gcgtacttat tggagtccag
    35341 aggctgttaa acgtgtaacg ggacatactt tagagggttg tgctgcagct ggcttcttac
    35401 atctaatcaa ctctggttct tgtacattgg atggtacagg tcaagctact cgagatggca
    35461 aacctgttat gaaaccattc tgggagttgg atgaaagtga agtgcaggct atgcttgaaa
    35521 atacagactt cccaccagca aaccgcgaat acttccgtgg aggaggattc tcaactcgtt
    35581 tcttgacgaa gggggatatg ccagtaacaa tggtacgtct caatcttcta aaaggggttg
    35641 gtccagtgct acaaattgca gaaggttata cacttgaact tcctgaagat gttcaccata
    35701 ctttagataa tcgtacagat ccaggatggc caactacttg gtttgctcca cgtttgacag
    35761 gaaaaggtgc tttcaagtct gtctatgacg tcatgaataa ttggggagct aatcacggag
    35821 ccataacata tggacacatt ggagcagact tgattacctt ggcttctatg ttgagaattc
    35881 ctgtcaatat gcataatgta cctgaggaag atatctttag acctaaaaat tggtccttat
    35941 ttggaacaga agatctagaa tcagcagact atcgtgcatg tcagttgttg ggaccactac
    36001 ataaataaaa cttgtttata taggaggtga acttacgtcc ctcctatcct tttaaaaaga
    36061 tttgttaaac aattcacaaa taattaaaaa cgaatacaaa aagtaatata atgatgttaa
    36121 ataaatagcg caaaggcgca ggaggaaaat tatatggcta cattttatgt tccggcagtt
    36181 aaccttattg gtaaaggtgt tgtaaatgaa gtgggtcctt atatcaagga acttggctat
    36241 aaaaaggcac ttttggtgac agataagtac atcgaaggca gtgacatttt acctaaggtt
    36301 ttaaaaccac tagatacaga aggaatcgaa tatgtcatct ttagcgatgt agagccaaac
    36361 cctacttgta agaatgtcac ggatggggta gctgctttgc aagaacatgg ctgtgacttt
    36421 atcatcagtc ttggcggggg ttctccacag gatgcagcta gttgtatttc tatcatggct
    36481 acaaatggtg gaaaaccaca ggattatgaa gggcttcata agtctgctaa aaaaggcttg
    36541 ccagttgtgg ctatcaatac aacggcaggt acatcagcag aaattaccat taactatgtg
    36601 attactgatg aagaacgcaa ggttaagatg gtaatggttg acaagaatag ccttgctctt
    36661 atctctgtta atgaccctga actcatgctt tccaaaccta aaggcctgac tgctgctact
    36721 ggtatggatg ctctgactca cgctgttgaa gctttggtaa cacctggtgc ttatgatgta
    36781 accaagaaac tgtctattgg tgctattgag cttatcaagg aatatcttcc tcgtgctgta
    36841 gcaaacggac atgatattga agcgcgtgaa ggtatggtca atgccatctt ccttggtggt
    36901 atgagcttta ataatgctgg tcttggctat gttcactcaa tggctcacca actcggtgca
    36961 gtatataatt tgccacatgg tgtttgctgt gccatgttgc taccagttat agaacgtgaa
    37021 aatgctaaac gtgtaccaga agctttccgc aatgttgcca aagccttggg acttcatgta
    37081 gaaggtaaat cagatcaaga atgtgccgat tatgcgattg ctgagattga gaagctttct
    37141 gagacagtag gtattcctaa gaaactgact gaacttggta ttgaagaaaa agatttcgac
    37201 tttgaatacc tttctaagaa tgccttgatt gatgcctgcg caccaggaaa tccatttatg
    37261 ccaaccttag aagaaacgat tgccttttat aaagagttat tttagcaagg attagacgac
    37321 aataggacaa ttcacctcta attattgaca tttcaggaaa aatcgcagta aaaacggcac
    37381 agccttcttt aaatgtgcta taatactaga aaaatacttg tggaggttcc attatggcaa
    37441 tatttttcat gatttttctg attgtttgtg tgctcctatt ggtgatagtc acactgagta
    37501 cagtttatgt ggttcgtcag cagtcggtgg cgattattga acgctttggg aaataccaaa
    37561 aggttgctaa tagcggtatt catattcgct tgccttttgg gattgactcg attgcagcac
    37621 ggattcagtt gcgcttgttg caaagtgata ttgtggttga gactaagacc aaggacaatg
    37681 tgttcgttat gatgaatgta gcgactcagt accgtgtcaa cgagcagagc gtgacagatg
    37741 cttactataa actcatacgt ccagaatctc agattaaatc ttatatcgaa gatgctcttc
    37801 gctcttctgt tccaaaatta accttggatg aattgtttga gaaaaaagat gagattgccc
    37861 ttgaggttca acaccaagta gcagaagaaa tgaccactta cggttacatt atcgtgaaaa
    37921 ccttgattac caaggtcgaa ccagatgcag aagttaagca atccatgaat gaaatcaatg
    37981 cggcgcaacg taagcgggtc gcagcacaag aattggcgga agctgacaag attaaaattg
    38041 tcactgcagc tgaagcagaa gcagaaaaag accgccttca tggtgtgggg attgcccaac
    38101 aacgtaaggc gattgtggat ggattggcag agtctatcac cgaactcaag gaagccaatg
    38161 ttggcatgac agaagaacaa atcatgtcta tcctcttgac caaccagtat ttggatacct
    38221 tgaatacctt tgcctctaaa ggaaatcaaa ccatcttttt accaaatact ccaaatggtg
    38281 tggatgatat ccgaacacaa atcttgtcag cccttcgcgc tgagaagaaa taatagacta
    38341 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttgccgtata gatgttactg
    38401 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcaacctgt ggctagtttc
    38461 ctagtttgct ctttgatttt cattgagtat aaagagcttg gcaacaggct ctttttgtat
    38521 tgcgtttatt aagaaaaaca aaaaacatcg atatacattt aactaaaaat tattgtatgt
    38581 tatctctctt aattaggaat gataagggaa taactagaaa gatttgtgaa tacaaactat
    38641 ttctgatata caaaatatac agtaataatg aatgatggga gatgggatga aagaatttca
    38701 atttgagaga aagcagcgtt tttctttgag gccatatgca ataggagctt gttcggtctt
    38761 gctaggaacg agtttatttt ttgctggtat gggtgatcag cctgtacagg atacagaaac
    38821 gagttcagca ctaattttaa gtcattattt ggatgagcag gatttatctg aaaagctgaa
    38881 atctgagttg caatggcttg aattagaaaa caagcttttg aacttatggg agcattaggt
    38941 tactatgaag gatttgttcc ttatgtttca aattaataca aaaaccaagc tgaagaagaa
    39001 gacaaaccgc tatctgataa atatattttt gaaaaaatct taggaaaaac atatgcagcc
    39061 ttcaaaaaag atcaaattaa tgagcgtgtc gagaaattag gtaagttaaa acctattaca
    39121 ataaattaca acggaaaatc agaagtaatt gatagtaaag aaaaattaca agagcttatg
    39181 aataaagccg ttaaagacga agtggctcaa atatagtaaa atgaaataag aacaggacaa
    39241 atcgatcagg acagtcaaat cgatttctaa aaatgtttta gaagtagagg tgtactattc
    39301 tagtttcaat atactataaa atcaggcaat accacggcta aaaagtttga gtttatcgaa
    39361 acaccagtgc aaaaactgaa aaaagcgatt tataaagctc atctcaaaga ttcagatgac
    39421 tttagaccag aaacatccac ataaatcttt ttgaaagctg tttgaagctt tgtccttgct
    39481 ttcttagttc atagatctga actttatctt cataactcaa tttcataata aaacacccca
    39541 aaagttagat ttattctgtc taacttttgg ggtgcagttc attaatcggt cgattttttt
    39601 ggtagaaaca gttgcctgat taagttgcaa gtcgatagac ggcttcggca taaatatcca
    39661 tagcacggta caaatcttct agaacggcac attcatttgc ctgatgttct gtctgcttcg
    39721 ctcctgggaa taaggcgccg aaggctacac aatttggcat ggtgcgagca aaagtggcac
    39781 caccggatga aatagcagga ctgttatcgc cagtcttttc ttggtagatt tgcatcagtg
    39841 tgctaacgag tttactgtct tttgcgacgt atagaggcgc tagatagtca aactcttcgt
    39901 agcggagttg gtagttttgt gcacatcttg taagcaactc tactagttct tccttgtcag
    39961 ctaagacagg agtccgaatg tcaatacgga tttcagaacg ttcatgattg atcatgagac
    40021 ctgcgacatt aaaggatagg tgaccagaag gttcatctgc tatatcacca aagatttgtc
    40081 ttcctgtgcc gtcttgacct gcttgtgttg caagaaagct gagagcaggg tgttcttgga
    40141 gaggagcaag aatggtagct agtcggatga cagcattgat accttgacta gcatccttag
    40201 catgctttgg cactccgaga accgttacgg tttgttcagt ggattggtaa tcataaccag
    40261 cttctttgag atcgttacaa acctgttcat agaggggacc ttggtagttg gccttgtctg
    40321 gtacaacgtt aaaggcgcct cctacttcaa gctctagttg atccgatcca gggccatgaa
    40381 gtttgacctg tagaagtcct ttttcagcat aggtcagagg aaaagatgag tcaggtgcaa
    40441 agcccatgct ggcctgttct tcgatggtat tgtagcgtgc catgcagcgc cagagggtct
    40501 cctcatcggt accaaagata aagcgtacgc gctttttgaa ctgaatacct tggtccagca
    40561 agctttttac tgcatagaga gctgcgagcg aagggccttt atcatcttgg acaccacgtc
    40621 cgaataccca gccgtctttg atagttgctt caaatggcgg tgtctgccaa tctgcttcat
    40681 cacctgatgg aacaacatcc aaatgacaga gaatggccag aagctctgct ccctgaccga
    40741 tttctgcata tccgtaataa cctttagggt caagataggt agtgaaacct atgtctcgac
    40801 aaatctctaa agttttttct aggacatctt ggattgcttg tccaaaaggt gttccatttt
    40861 ctccttcatt gagtactgaa ggataggaaa tcaaggtttt taatgatata agaaattcat
    40921 ctttaacttg atttgttata tctattttca tggaatcacc tcactcacta ttttatagga
    40981 atggaaggaa ggttccaagg agaagaaggg cgatggtcac tacaataata gcgactacga
    41041 gtttgcccat gaatttccac caagtaccaa tgttgatacg tccaagtgca agagctccca
    41101 tcacaatacc agatgttggt gcaatcaagt tcaagacacc tgaagcagat tggtaagcag
    41161 tgataatcaa gctaggacgg acatttacaa attctccaag tggagccatg atacccatag
    41221 ttgcgctggc aagaccagat gaagatggga tcaagaatga cataggtaga tagaagatat
    41281 aagttacaac gataaagact tgtgaagata gaccgctcaa gccttcttta ccccagttga
    41341 ggattgtatc ggtaatcata ccgtcgttca tgataacttg aataccacga gcaatcgcta
    41401 cgatcaaggc aacactgagc aagtcagcag caccattcat gaaggaagag ataatcttat
    41461 cttctttaag accataaata acaccaatca ggatacccat aaaggcaaag agcattgcgc
    41521 cttctgggaa gtaccaagta cctagtgcag aagtagatga accgacaata ttgccaataa
    41581 ctggaagacc agtcaaccaa gcattaaagt catcaaaaat ggtaacgcca aggtctgtcc
    41641 atggaatgaa gctcaatacc atcaagatga atgtcaacac aaataagaag agaactgatt
    41701 tttgtttgct gctaagtgta gattctacag atgaagattc ttctacgtta aagtgtttca
    41761 aatcttcttt gcgagtacta taaaccagtg acttagtcgg atctttttga atcttatccg
    41821 cataacggta aacaaaccaa gtactaagag cagtcaaggt aacccagaag atcagacgaa
    41881 gtacgatacc gtcccctgta ccaactcccg cagtcgctga agcaatacct gtcgcaaatg
    41941 gattcagagt agatgccaaa cagccgattt gagaaccgag caaaataatt gcaacaccag
    42001 tcaggctatc aaaaccaacg gccatcataa ctggcacaag gagtggatag aaggccattg
    42061 tttcttcacc cataccataa gttgtaccac cgagggcaaa caaaggcatc agtaccaaaa
    42121 ttaacatttt ttcgcggccc ttatacttct tcacgataga ggcaatccct acgtcaagag
    42181 caccagtttt gttgacaatg ccaaggaaac caccaaccat aaggatgaag aaggctacat
    42241 caatcgctgc gctcgtttct ttaatgagcg aaccttcctc tggatgagta cctagcatag
    42301 cccgaatcgg tgccatgagg acatcccaaa tcccttgtgg attttgaggc tgagtctcgt
    42361 aaataccttc tataaaggcc cccgcaggga taaaccaagt tagcacggcc ataatagcaa
    42421 tgattatcaa taatacggtg taagatgaag gcatcttaaa ccctttttta gctttttcac
    42481 tcatttgttt ttcctcctga tgtctaacaa agtgtaaaaa accaactact ttcttaaata
    42541 aacattcaag aaaacgcttt ctatttatat ttgttttacc atattaaagt ctaaaaaact
    42601 aatatctttt gaaatattgt acatgttttc aagaataatt tctaatttga tataaagata
    42661 ctagaaatag aatacatctt attagtaaaa caacttatcc tttttcaata attgttccgc
    42721 tttcagattc aatcaaggcg cctagatttt caagggaagt aataactgct tttccttctg
    42781 gacgaccatt gacaaaagcg atagctgctt ctacttttgg aagcatgcta cctggtgcaa
    42841 actgatcttg tttgatatat tcttccagct gggcaacatt cacatgttcc aatttttcct
    42901 ggtttggctt gttgtagtta acaaatacat aatctacacc tgtcaaaatg atgaagaggt
    42961 ctgcatcaac caattctgcc aaacgttggg aagcgaagtc tttatcaata accgcttcga
    43021 caccagtcaa atgtccattg ttttctttga cgacgggaat accgccacca cctgcagcta
    43081 cgacgacttg accattattt aaaagagtac ggatggtttc aatttctttg atgtcaacag
    43141 gttttggtga ggcaacgacc ttacgccagc cacggccagc atcttccttg aaagtcgctc
    43201 cgcttttttc ggcttctgct tttgcttctt cttctgaata gaaaggaccg attggtttac
    43261 tcaagttaac aaaagctgga tcatttttat ctacgacaac ttgcgttaca acagaggcaa
    43321 catttttttc gatgccttca tccaagagag cattttgcaa agcatttttc aaccagaaac
    43381 cgatgctacc ttctgtcata gcgacaagtg agtcgagtgg gaaggcaggg ttcttttcag
    43441 agtctgatgc caaatgttgg agcaagagat tcccaacttg aggtccatta ccgtgagtga
    43501 taatcaaatc atctccattt ttaatcaatt ttacaagatg cttagctgtt tcaactaaag
    43561 cttcttgttg agcctttgct gatgggtcag aagaaagaat cgcatttcct cccaaagcta
    43621 ctacaatttt acgatttgcc ataaattctc ctttatcaca ctcaatagaa tgcgtttaga
    43681 tttcaattta atgatttttc acatatttta taagaaataa tagattacca ttacataaaa
    43741 gaggaccgga ctaaagctat tagtcgcagc cctcatagct gttggtagac ggtttattat
    43801 ctaaaattat actttaggaa tataaaggtt accaagtgta gcagccataa cagctttgat
    43861 agtgtgcata cggttttctg cttgatcgaa gtggcgagcg tacttgctgc ggaagacttc
    43921 gtctgttact tccatttctt ctacaccaaa tttttcagca acgtctttac cataaacagt
    43981 gtgagtatcg tggaatgctg gcaagcagtg taggaagatc aagttttcat tgcctgcttt
    44041 tttaactaag tccatattga cttggtaagg tttaagaaga gctacacgtt ctgcgaattt
    44101 gtcttcttca cccattgata cccaaacgtc tgtgtaaaga acgtctgcat ctttaactgc
    44161 ttcatcagca tcttcagtga tgagaacatg tgcgccactt tctttagcaa atccttctgc
    44221 caattcaacg atttcttttt ctgggaagag ttcttttggt gagaagatgt gaacattgac
    44281 accaaggata gcacctgtta cgagcaagct gttggcaacg ttgttacgtc catcaccaca
    44341 gtataccaat gtcaagcctt ccaagcgacc gaagttttct tgaacagtca agtagtcagc
    44401 gagcatttga gttgggtgcc attcgtcagt tagaccgttc catactggaa cgcctgagaa
    44461 ttctgccaat tcttcaacca tacgttggct gaatccgcgg aattcaatcc cgtcaaacat
    44521 acgtcccaat actttagcag tatcttcagt agattctttt ttacccaact gaatatcatt
    44581 tgctccgagg tattctgggt gagcaccaag gtcgatagcc gcagttgtaa aggctgcacg
    44641 agtacgagta gatgtttttt caaataggag agcgatattc ttgccagcaa ggtagtggtg
    44701 ttgaatattg cgttttttca aatctttcaa gtgagctgaa agaccaataa ggtattctaa
    44761 ctctgcacgg gtaaagtctt tttctgctaa gaagctgcgt ccttggaata ctgaatttgt
    44821 cattttatta tttcctcttt ctatttttta cattttctat tgacgaatgc cgaacagcga
    44881 ttacacttct tcacgttcaa atggcataga catacaacga ggtccaccac ggccccgaac
    44941 caattcactt ccgcgaatct taatcaagcg aagcccgtat tcttccaaaa tcttattggt
    45001 cacggtattg cggtcataaa caactaccac accaggtgcg atggtcaaag tgttagaacc
    45061 gtcgttccat tgttcacgcg cagctgctac gatattgcca ccaccgcaac gaatcaaatg
    45121 aactttttct acaccaaggt tttgagcaag aagttcagct aagtcacctt tctcttcaac
    45181 gattttaagt ttttcgtttt cgtaagtaac tgagtaaacg tgaaggtcgc cttcgatttc
    45241 tgggtgaata gtgaatttgt catagtctac catagtgaag acagtatcca agtgcatgaa
    45301 tttacggttg ttagcaaatt caaaggccaa aactttcttg aagccaacat ttttcttgaa
    45361 gatgttgacc aaaagttttt cgatagaagc tgcgtctgta cgttgagaaa tacctactgc
    45421 aaggacgtct ttagaaagaa ctagctcgtc tccaccttcg atacgcgtat cttcttcacg
    45481 gttgtagacc aaatccactt ttccgccata gattgggtgg tatttgaaga tatacttacc
    45541 gtagagtgtt tcacggttac gagtgtctgc aaacatgtgg ttaagcgata cggcgtttcc
    45601 aattgttgca aatgggtcgc gagtgaaata gaggtttggc atcgggtcaa ttgcaaatgg
    45661 ataatctgat tcaactaagt cagttagatc tttagcttcg tcaggaattt ctggcaattc
    45721 aactttttga atcccagcca ttgttttttc aaccaattct tggttgtcct tgatgccgtg
    45781 aagcaattca cgaatagcaa ccttggtttg acgatcacgg atgttggctt cgtctaagta
    45841 ttcctcgata aattgatcgc ggatttctgg agaggtcaat gattcagcag cgagttgttc
    45901 taggtagaga acctcaattc cttcatcgcg aagagcttgg gcaaatgcat catgttcttt
    45961 ttgagcatct tccaagaaag gaatatcatc aaaaagaagc ctttcaagat agtccggcaa
    46021 caagttttct aactccttgc ctggacggtg caacataact tttttcagtt tcccaatttc
    46081 tgagaagacc tgaattggat gtgaagacat gtattttcct ccttaaaaat tttgacttgg
    46141 caccattttg ggtaccgctt acatgtatgt tataacgcaa ttcctaggta atgtcaatgg
    46201 ctataatttc tcggaaaata atataaatta tgatgtttag cacaatttta tgttattata
    46261 cataacatag gatagaatac atagatacaa atgtataaac ttctataaaa aggatataaa
    46321 atttttttaa aaaatttttc aaaaaatata caaatgacca aaaagtgtcc aattatcatc
    46381 tggttatcac ttggatctgt ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa
    46441 cattcttttg aagatagatt ttggagaagc atttcttgtt caattgtaca aattatagaa
    46501 tcttttctga gtatttagga agagataatt atcttattga ccctcttttt attttttgtt
    46561 atagtcgacg aggtgatagt ttagaataat cacttattca caatctgtgg aaaagtctgg
    46621 atagtgaatg gtcttcacac aatgacctga aagaagcctg agaataatta tggagagtag
    46681 cattctgaga ggtgttagca gaaccatatg acagagctgt ttgaagaggg aatattgagg
    46741 agaaaaatcc tgagcctacc agttggagtt ggaaagagct ggctgttaga tcatggttta
    46801 ttatccacaa cctgtggata accttgtgaa caagagaagt tgcaaaagaa ggagatatat
    46861 aacgatgaag aaaatcaaac cgcatagacc gttaccaagt cagactcagc tagcttatct
    46921 gggagatgaa ctagcagcct ttatccattt tggacctaat actttttata atcaggaatg
    46981 gggaacaggt caggaggatc ctgaacgctt taacccgaca cagttagacg cacgtgagtg
    47041 ggttcgcgtg ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca agcaccatga
    47101 tggctttgtc ctttatccga cagctcacac agattattcg gttaaggtca gtccttggag
    47161 gagaggaaag ggcgacttgc tccttgaagt atcccaagct gccacagagt ttgatatgga
    47221 tatgggggtc tacctgtcac cgtgggatgc ccatagtccc ctctatcatg tggaccgaga
    47281 agcggactac aatgcctatt atctggctca gctgaaggaa atcttatcaa atcctgccta
    47341 tggaaatgga gggaaatttg ctgaggtttg gatggatggt gccagaggag agggcgcgca
    47401 aaaggttaat tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc agggcaattg
    47461 cttgattttt tcaacagaag gcaccagtat ccgctggatt ggcaatgaac gagggtatgc
    47521 aggtgatcca ctgtggcaaa aggtgaatct tgataaacta ggaacagaag cagagctgaa
    47581 ctatcttcag cacggggatc cctcgggcac gattttttca atcggagagg cagatgtttc
    47641 catccgtcca ggctggttct accatgagga tcaggatcct aagtctctcg aggagttggt
    47701 cgaaatctac tttcactcag tagggcgagg aactccactc ttgcttaata ttccgccgaa
    47761 tcaagctggg ctctttgatg caaaggatat tgaacgactt tatgaatttg cgacctatcg
    47821 caatgagctc tataaagaag atttggctct gggagctgag gtatctggtc cagctctttc
    47881 cgcagacttt gcttgtcgcc atttgacaga cggccttgag accagctctt gggcaagcga
    47941 tgcagacttg cccatccagt tagaactcga tttaggttct cctaaaactt ttgatgtaat
    48001 tgagttaaga gaagatttga agctagggca acgaatcgct gcttttcatg tgcaagtaga
    48061 ggtggatggt gtctggcagg agtttggcag gggcttcaca gttggtcata agcgcctctt
    48121 gcgaggtccg ctagtagagg cacaaaaggt gcgcgtgatg attaccgagg cacaatctat
    48181 ccctgtattg accaagattt ccctttataa aactcctggg ttatcaaaaa aagaagttgt
    48241 tcaggaacta gcatttgcag aaaaaagcct agctgtggca aagggagaga ctcttcattt
    48301 taggattgaa cgtagtgaaa gtagctcctc tttagaggct aagatttcga ttcaaccggg
    48361 gacaggtgtc catggtgtcg cctatcagga tgagattcaa gtccttgcgt ttcaagctgg
    48421 tgagactgaa aaaagtctga cgctaccaac cttgtatttc gcaggagata aaaccttgga
    48481 tttctatctg aacctaacgg tggatggtca gcttgtggat caacttcaag tccaagtttc
    48541 ataaaagaag aacctttgcg cgatgcaaag gttcttttgg ttattagtga cttggtaacc
    48601 agctgagggt gaaagttagt tgttcagctt ttaagaggtc ttggtgttga atagttgata
    48661 cgagtgtttt gtccagtcgg cattctttga caaagttaaa atggttgtgg ttttgtttag
    48721 tatggatatc cagccattta tcttctttag ctaggtagac tcgtagatgg tcaaagagag
    48781 ggattccgag gtcatagctt ggttttcctg gacaggttgg ataaaatccg agagctgacc
    48841 agatgtacca agcagagaga ctaccattgt cttcatctcc aggataggct tcccaacttg
    48901 ggtgaaaagc tttctgacgg agcgtcttga taagaagggc agtgtagtca gggtaatcgc
    48961 tgtagcggaa gagataagga atgtggaaac taggctggtt ggaaatggct atttgtccaa
    49021 aaggagcagt agccatctcg ctcatttcgt gaatttcgta accatagcct gttgtttcaa
    49081 agaggggagc atcttgacag gctttcaaaa gatagttgct aaaggtttct tttccaccca
    49141 tcagttggat taagccaggg atgtcgtgga gaacgcctaa agtagcttga atggcagagc
    49201 attcagcgta gtctcgcccc caactataag gagagaagtc agggtgaaag tttccttgat
    49261 tgtctcgtgc tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag
    49321 tagccttgta ggtttcagcg atttctatgt tctctagttt tttggcacag ctggcgatac
    49381 aaaagtcact ataggcatag tctagagtat ggctaacact ttcgtggtgg tcggtagaga
    49441 ggtaacctag ttcttggtat tgggctagtc cgtggcggcc attgatgccg agagggtcgg
    49501 ctttgctggc tgtttcgagc atggcttgga agagttctcc ttctaggtca ggggccatgt
    49561 ccttgcaggc gctatctgcg ataataccgt ctaaaagtgt acctggcatc ataccccgtt
    49621 catctggagc cagccatttt ggaaggaaac cagtatcgcg gtagctattg aggaaacctt
    49681 ctaaaaagcg ttgatagtgc tccggtatga taagggcaaa gagggggaag gtggtgcgga
    49741 aggtatccca gaaaccattg ttgctaaaga ggacaccagg cttgacagta ccagtagcca
    49801 gatccatgtg gatggcttgc cctgactcat caacctcata aaaagtctgt gggaagagga
    49861 agagtctgta gagacagtgg tcaaagaagg ttcggtcagc ctctcctgtc tctataatgt
    49921 caaaacgatg gaggagattt tcccaatccg cttgggcact tgctttacag ctatcaaaat
    49981 cttcttgagg tagattgatt agagcttgag aaggagagat gaaagaagtg gctagttgca
    50041 tctcggtttg actacttgct aagtcaattc gccagtctcc cccttcttgg ctgatagcaa
    50101 gaatatccgt gttcatttgc agggcagtga acatcgttag cgaatttttg ttagtttcag
    50161 ttttaccttc ttgtcgcagg gcaagagtcc gcttatctac ttgctctacg gtcagttcat
    50221 ctgctgcgtg aagatagagg gagagggctt tgccttgctt ttgattcaaa cgaatagaag
    50281 caccatagca agtcggtgtg agctgggttt caatctgata acgcagagaa aagagcttca
    50341 aatagtgagg ctggaagcaa gctttatcta tatcataaga agactggcgg tgaaagaggc
    50401 tgtctccacc cagttgactg gtgacaggtg tcagaaggag ccaagagtag tccccaatcc
    50461 aaggactggg ctggtgagtt aatcgaatcc cctgaaagat aggcagatgc ggatcaaaaa
    50521 accaagatcc atcctggtca ctggtctggg gcacaaagta attcattcca aaaggcacgc
    50581 ctgtgtatgg cagggtattt ccccgagaga aggcatgctt gctagcagta ccaaagcggg
    50641 tatcgatggt ttcaagtagt ggtttcatag tctttccttt agctgttttt ctacattata
    50701 tcagaaaaag agggccttta gaaaaggagt ttcaaaaata actattttgt agaaaaatga
    50761 ctatcatttg tgtatgtatt ttctgtctca aaagctatat actgaacatg aaacttgttt
    50821 gaaagaggta aaatttaaaa tggtttattc gaaagaaatc gtcagagagt ggctggatga
    50881 agtagcagag cgggctaagg accatccaga gtgggtggat gttttcgagc gttgctacac
    50941 cgataccttg gacaatacgg ttgaaatctt agaagatggt tcaacttttg tcttgactgg
    51001 ggatattcct gctatgtggc ttcgggattc gacagcccaa ctcagaccct accttcatgt
    51061 agctaaaaga gatgccctcc tgcgtcagac cattgcaggt ttggtcaaac gtcagatgac
    51121 cttggtactc aaggatcctt atgccaattc cttcaacata gaggaaaact ggaaggggca
    51181 ccacgagacc gaccacaccg accttaatgg ctggatttgg gaacgcaagt atgaggtgga
    51241 ctcgctttgc tatcctttgc agttggctta tctcctctgg aaagaaactg gcgagactag
    51301 tcagtttgat gagacttttg tcgcagcgac taaggaaatt cttcatctgt ggacggtaga
    51361 acaagatcat aagaactctc cttatcgttt tgtccgagat acggaccgca aggaagacac
    51421 cttggtaaat gatggctttg gacctgattt tgcagtgaca ggaatgactt ggtcagcctt
    51481 tcgtccgagc gatgactgct gtcagtatag ttacttgatt ccgtcaaata tgtttgctgt
    51541 agtagtcttg ggttatgtgc aagaaatctt cgcagcatta aacctagctg atagccagag
    51601 tgttattgct gatgccaagc gtcttcagga tgaaatccaa gaaggaatcg aaaactacgc
    51661 ttacaccacc aacagcaagg gcgaaaagat ttacgctttt gaagtggatg gcctaggaaa
    51721 tgccagcatc atggatgatc caaatgtacc aagtctacta gctgcgccct atctgggcta
    51781 ctgttcggtc gatgatgaag tgtatcaagc tactcgtcgt accattttga gctctgaaaa
    51841 tccatatttc taccaaggag aatacgctag cggtctcgga agttctcata ccttctatcg
    51901 ctatatctgg ccaatcgccc tttctatcca aggattgaca acaagagata aggcagagaa
    51961 aaaatttttg ctggatcagc tggttgcctg cgatggtggt acaggtgtca tgcacgaaag
    52021 cttccacgta gatgatccga ccctctactc tcgtgaatgg ttctcctggg ctaacatgat
    52081 gttctgtgag ttggtcttgg attatttaga tattcgctaa ggggctcgct ttagctcaac
    52141 cgattcttat cagaatcaca agtttacatt taaaacgtta aaatttaaat ttagaatgag
    52201 gttttacttc atggaaaatg ttgttgtaca tattatctca catagccact gggaccgtga
    52261 gtggtacttg ccttttgaaa gccatcgtat gcagttggtg gaattgtttg acaatctctt
    52321 tgaactcttt gaaaatgacc ctgagttcaa gagtttccac ttggatggac aaactattgt
    52381 ccttgatgac tacttacaaa ttcgccctga aaatcgcgac aaggtccaac gctacattga
    52441 cgagggcaaa cttaaaattg gtccctttta catcttgcag gatgactact tgatctccag
    52501 tgaagccaat gtccgcaata ccttgattgg tcaacaagaa gctgccaaat ggggtaaatc
    52561 aacccagatt ggctactttc cagatacctt tggaaatatg ggacaagcgc ctcaaattct
    52621 tcaaaaatca ggcattcacg tggcggcctt tggtcgtggt gtgaagccga ttggatttga
    52681 caaccaagtc cttgaagatg agcagtttac atcccagttt tcagaaatgt actggcaggg
    52741 tgtggatggt agtcgtgttt taggtattct ctttgctaac tggtacagta atgggaatga
    52801 aatcccagtt gacaaagatg aggccttgac cttctggaaa caaaaattgt cagatgtgcg
    52861 tgcctacgct tcgaccaacc aatggttgat gatgaacggc tgtgaccacc agcctgtaca
    52921 gaaaaatctg agcgaagcca ttcgtgtggc aaatgaactc ttcccagatg taatctttgt
    52981 tcatagttct tttgatgaat atgttcaagc tgtagaaggt gcgcttcctg aacacttatc
    53041 aactgttaca ggcgagttga ccagtcagga aacagatggc tggtacacac ttgccaacac
    53101 ttcttcatcc cgcatttacc taaaacaagc cttccaagaa aatagcaacc tcctagagca
    53161 agtggtagaa cccttgacta ttatcactgg tggacataac cacaaggacc agttgaccta
    53221 tgcttggaaa acacttttgc agaatgcgcc acatgatagt atctgtggct gtagcgtgga
    53281 cgaagttcac cgcgagatgg aaacgcgttt tgccaaggtc aaccaagtag gaaactttgt
    53341 taaaagtaat ttgctcaacg agtggaaggg taaaattgct acggataagg ctcaaagtga
    53401 ctatctcttt actgtcatta acacaggctt gcatgataag gtcgatactg tcagcacagt
    53461 gattgatgtg gcgacttgtg atttcaagga attgcaccca acagaaggct acaaaaagat
    53521 ggccgctctt atcttgccaa gttaccgtgt ggaggacttg gatggtcgtc ctgtagaggc
    53581 tacaatcgaa gacctcggag ctaattttga atacgattta ccaaaagaca agttccgcca
    53641 agctcgtatt gctcgacaag tgcgcgtgac cattccagtt cagctagcgc cgctttcttg
    53701 gacaaccttc caattgctgg aaggaaaaca agaacaccgt gagggtattt accaaaacgg
    53761 agtgattgat acaccattcg taacggtgag tgtggatgac aacatcacag tctatgacaa
    53821 gacaactcac gaagcctatg aagactttat ccgctttgaa gaccgtgggg acatcggaaa
    53881 cgagtatatc tatttccaac caaaaggaac agagccaatc tttgcagagc ttaagggcca
    53941 cgaggtcttg gaaaacacag cttgctatgc taaaatcttg ctcaaacatg aattgaccgt
    54001 gcctgtcagc gcggatgaaa agctagaaga agagcaacaa ggtatcatcg agtttatgaa
    54061 gcgtgaggct ggacggtcag aagaattgac aaacattcct ctggaaactg agttgactgt
    54121 cttcgttgac aatccacaaa tccgcttcaa gactcgcttt accaacactg ccaaggatca
    54181 ccgtatccgt ctcttggtca agactcataa cacgcgtcca agtaatgatt ctgaaagtat
    54241 ctatgaggtg gtgacacgac caaacaaacc agctgcttca tgggaaaatc ctgaaaatcc
    54301 tcaacaccaa caagcttttg tcagtctgta tgacgatgaa aaaggggtga ctgtatccaa
    54361 taagggattg aatgaatacg aaatccttgg ggataacacc attgccgtga ccattttgcg
    54421 tgcatcaggt gagctaggtg actggggcta cttcccaacg ccagaagcac aatgcttgcg
    54481 ggagtttgaa gtcgagtttg cacttgaatg ccaccaagcc caagaacgct tctcagccta
    54541 tcgtcgtgcc aaagccttgc agacatcgtt taccagcctt cagcttgcta gacaggaagg
    54601 aagcgtggtt gcgattggta gcctcttgag ccattctgtt ctcagcatac cgcaagtttg
    54661 tccaacagcc tttaaagtgg cggaaaatga agaaggctat gtcctccgtt actataatat
    54721 gagtcaagaa aatgtgcgca tatcagaaca tcaacaaacc attcttgact tacttgagcg
    54781 accatatcca gttcattcag gactattggc tccacaagag attcgtacag aattcatcaa
    54841 aaaagaagaa atttaatttc aaaaagtaaa catcaaaaga aaggaggggc gaaaaagtaa
    54901 gaactaactg ctgattcgcc cctttttatg gtaaaaacaa tgaccattgc aacgattgat
    54961 atcggaggga ctgggattaa gtttgccagt ctgactcctg atgggaaaat actggataag
    55021 acaagtattt caacgcctga aaacttggag gatttactaa cgtggctaga tcaacgcttg
    55081 tcagaacagg attacagtgg gattgctatg agcgttccag gtgcggtcaa tcaagagaca
    55141 ggtgtgattg atggcttcag tgcggtgccc tatatccatg gcttttcttg gtatgaggcg
    55201 cttagctctt atcagctacc tgtccattta gaaaatgatg ccaactgcgt tggactcagt
    55261 gaactactag ctcatccaga gcttgaaaat gcagcctgtg tcgtgattgg gacagggatt
    55321 ggcggagcca tgattatcaa tggtagactt catcgaggtc gccacggtct gggtggagaa
    55381 tttggctaca tgacaaccct tgcccctgct gaaaaactta ataactggtc gcaactagca
    55441 tcaactggga atatggtacg atacgtgatt gaaaaatctg gtcatactga ttgggacggt
    55501 cgcaagattt accaagaggc cgcagctggt aatgctcttt gtcaagaagc cattgagcgc
    55561 atgaaccgca atctgacgca aggcttgctc aatatccagt atctcatcga tccagatgtc
    55621 atcagtctgg gtggctctat cagtcaaaat ccagatttta tccaaggtgt taagaaggct
    55681 gttgaagact ttgtcgatgc ctacgaagaa tacacggtcg caccagttat ccaggcctgc
    55741 acctatcacg cagatgccaa tctctacggt gcccttgtca actggctaca ggaggaaaag
    55801 caatggtaag atttacagga cttagtccca aacaaacgca agctattgag gttttaaaag
    55861 gtcacatttc tctaccagat gtggaagtgg ctgtcactca gtctgaccaa gcctctatct
    55921 ctatccaggg tgaggaaggt cactatcaat tgacctaccg caaacctcac caactttatc
    55981 gtgccttgtc cttgttggta acagttctag cagaagctga taaagtagag attgaggaac
    56041 aagcagctta cgaagatttg gcttacatgg ttgactgttc tcgaaatgcg gtgctgaatg
    56101 tggcttctgc caagcagatg attgaggtct tggctctcat gggctactca acctttgagc
    56161 tttacatgga agacacttac cagattgaag ggcagcctta ctttggctat ttccgtggag
    56221 cttattcagc agaggagttg caggaaatag aagcctatgc tcaacagttt gacatgacct
    56281 ttgtaccatg catccagacc ttggcccact tgtcggcctt tgtcaaatgg ggtgtcaagg
    56341 aagtgcagga gctccgtgat gtagaggaca ttcttctcat tggcgaagaa aaggtttatg
    56401 acctgattga tggcatgttt gccacgttgt ctaaactgaa gactcgcaag gtcaatatcg
    56461 ggatggacga agcccacttg gttggtttgg gacgctacct gattttgaac ggtgttgtgg
    56521 atcgtagtct cctcatgtgc caacacttgg agcgcgtgct ggatattgct gacaaatatg
    56581 gtttccactg ccagatgtgg agtgatatgt tcttcaaact catgtcagcg gatggccagt
    56641 acgatcgtga tgtggaaatt ccagaggaaa ctcgtgtcta cctagaccgt ctcaaagacc
    56701 gtgtgactct ggtttactgg gattattatc aggatagcga ggaaaaatac aaccgtaatt
    56761 tccgcaatca tcacaagatt agccatgacc ttgcatttgc agggggagct tggaagtgga
    56821 ttggctttac acctcacaac cattttagcc gtctagtggc tatcgaggct aataaagcct
    56881 gccgtgccaa tcagattaaa gaagtcatcg taacgggttg gggagacaat ggtggtgaaa
    56941 ctgcccagtt ctctatccta ccaagcttgc aaatctgggc agaactcagc tatcgcaatg
    57001 acctagatgg tttgtctgcg cacttcaaga ccaatactgg tctaacggtt gaggatttta
    57061 tgcagattga ccttgccaac ctcttaccag acctaccagg caatctcagc ggtatcaatc
    57121 ccaaccgcta tgttttttat caggatattc tttgtccgat tcttgatcaa cacatgacac
    57181 ctgaacagga caaaccgcac ttcgctcagg ctgctgagac gcttgctaac attaaagaaa
    57241 aagctggaaa ctatgcctat ctctttgaaa ctcaggccca gttgaatgct attttaagta
    57301 gcaaagtaga tgtgggacga cgcattcgtc aggcctacca agcggatgat aaagaaagtt
    57361 tacaacaaat cgccagacaa gaattaccag aacttagaag ccaaattgaa gacttccatg
    57421 ccctctttag tcaccaatgg ctgaaagaaa acaaggtctt tggtttggat acagttgaca
    57481 tccgtatggg cggactcttg caacgcatca aacgagcaga aagccgtatc gagttttatc
    57541 tggctggtca gcttgaccgc atcgacgagc tggaagttga aatcctacca tttactgact
    57601 tctacgcaga caaggatttc gcagcaacta cagctaacca gtggcatacc attgcgacag
    57661 cttcgacgat ttatacgact taatactctt cgaaaatctc ttcaaaccac gtcagcttcc
    57721 atctacaacc tcaaaacagt gttttgagca gcctgcagct agcttcctag tttgctcttt
    57781 gattttcatt gagtataaaa acaagaacac cttgcttggc gcagggtgtt tcgcgtgaaa
    57841 cagaagaatt atctggtttc aaatgctaca gttaaaatta gtaaaacaag aaatagaagc
    57901 tgaaaagcca gcatctgtag aagcttggat catttccgtc aaattaaaaa aggttgctac
    57961 cgacatatat agattccaaa aacaaaaacg ttagcggaac tagcagatgt gattttatgg
    58021 agtttcgatt ttgtaaatga tcatgctcat gcatttttca tggataatgt tgagtggagt
    58081 catgcagatt cttactttct tagctttgtt agtgacgatg ttgaagaacg ttacatagaa
    58141 aatgtctatc tggatagcct aagtgtcaaa caaaaattta agtttatttt cgacttcggt
    58201 gatgaatggc gttttgaatg ctaagtgctg agagaaatcg agacagagga cgaagaagct
    58261 tatctcgtac gttcggttgg aacgttgcca gaacaatatc cagattatga tggttttgac
    58321 tatgaagaat ggtaaaattg aaatcagtct gtgtaggctt agtatttcaa tagacttcct
    58381 gcaaaactag aatcctagtt catgattgat aataccagca ctcaaattca ttcgtaatcc
    58441 gaagcgttta cgatgatttc gataggttgt tgaaaatatt ttaaacgttt ttactttggc
    58501 aaagatgttc tcaaccttgc ttctttcctt agatagcgca tggttatagg ctttattttc
    58561 agctgttagc ggcttgagtt tgctggattt acgtggagtt tgtacttgag gatatatctt
    58621 catgagccct tgataaccac
//
LOCUS       DBEJJE010000006        53836 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEJJE010000006 DBEJJE010000000
VERSION     DBEJJE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 53836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.06"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(115..330)
                     /locus_tag="ACL3F5_000370"
     CDS             complement(115..330)
                     /locus_tag="ACL3F5_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514232.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1200..2450)
                     /gene="ilvA"
                     /locus_tag="ACL3F5_000371"
     CDS             complement(1200..2450)
                     /gene="ilvA"
                     /locus_tag="ACL3F5_000371"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0514233.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2500..2856)
                     /locus_tag="ACL3F5_000372"
     CDS             complement(2500..2856)
                     /locus_tag="ACL3F5_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0514234.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3094..3330)
                     /locus_tag="ACL3F5_000373"
     CDS             complement(3094..3330)
                     /locus_tag="ACL3F5_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514235.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3437..4459)
                     /gene="ilvC"
                     /locus_tag="ACL3F5_000374"
     CDS             complement(3437..4459)
                     /gene="ilvC"
                     /locus_tag="ACL3F5_000374"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0514236.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4525..5001)
                     /gene="ilvN"
                     /locus_tag="ACL3F5_000375"
     CDS             complement(4525..5001)
                     /gene="ilvN"
                     /locus_tag="ACL3F5_000375"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0514237.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4994..6694)
                     /locus_tag="ACL3F5_000376"
     CDS             complement(4994..6694)
                     /locus_tag="ACL3F5_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0514238.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6895..8562)
                     /locus_tag="ACL3F5_000377"
     CDS             complement(6895..8562)
                     /locus_tag="ACL3F5_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0514239.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8565..8930)
                     /locus_tag="ACL3F5_000378"
     CDS             complement(8565..8930)
                     /locus_tag="ACL3F5_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0514240.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9087..9275)
                     /gene="rpmB"
                     /locus_tag="ACL3F5_000379"
     CDS             complement(9087..9275)
                     /gene="rpmB"
                     /locus_tag="ACL3F5_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0514241.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9391..9567)
                     /locus_tag="ACL3F5_000380"
     CDS             complement(9391..9567)
                     /locus_tag="ACL3F5_000380"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0514242.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9678..9875)
                     /locus_tag="ACL3F5_000381"
     CDS             complement(9678..9875)
                     /locus_tag="ACL3F5_000381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514243.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(10303..11847)
                     /locus_tag="ACL3F5_000382"
     CDS             complement(10303..11847)
                     /locus_tag="ACL3F5_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0514244.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12060..12362
                     /gene="gatC"
                     /locus_tag="ACL3F5_000383"
     CDS             12060..12362
                     /gene="gatC"
                     /locus_tag="ACL3F5_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0514245.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12362..13828
                     /gene="gatA"
                     /locus_tag="ACL3F5_000384"
     CDS             12362..13828
                     /gene="gatA"
                     /locus_tag="ACL3F5_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0514246.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13828..15270
                     /gene="gatB"
                     /locus_tag="ACL3F5_000385"
     CDS             13828..15270
                     /gene="gatB"
                     /locus_tag="ACL3F5_000385"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0514247.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15399..15959
                     /gene="efp"
                     /locus_tag="ACL3F5_000386"
     CDS             15399..15959
                     /gene="efp"
                     /locus_tag="ACL3F5_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0514248.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15981..16370
                     /locus_tag="ACL3F5_000387"
     CDS             15981..16370
                     /locus_tag="ACL3F5_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0514249.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16363..16785
                     /gene="nusB"
                     /locus_tag="ACL3F5_000388"
     CDS             16363..16785
                     /gene="nusB"
                     /locus_tag="ACL3F5_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0514250.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16835..17071)
                     /locus_tag="ACL3F5_000389"
     CDS             complement(16835..17071)
                     /locus_tag="ACL3F5_000389"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0514251.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17084..17557)
                     /locus_tag="ACL3F5_000390"
     CDS             complement(17084..17557)
                     /locus_tag="ACL3F5_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514252.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17575..17760)
                     /gene="briC"
                     /locus_tag="ACL3F5_000391"
     CDS             complement(17575..17760)
                     /gene="briC"
                     /locus_tag="ACL3F5_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR0514253.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17919..18686)
                     /locus_tag="ACL3F5_000392"
     CDS             complement(17919..18686)
                     /locus_tag="ACL3F5_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0514254.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18683..19549)
                     /gene="accD"
                     /locus_tag="ACL3F5_000393"
     CDS             complement(18683..19549)
                     /gene="accD"
                     /locus_tag="ACL3F5_000393"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0514255.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19586..20953)
                     /gene="accC"
                     /locus_tag="ACL3F5_000394"
     CDS             complement(19586..20953)
                     /gene="accC"
                     /locus_tag="ACL3F5_000394"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0514256.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20965..21387)
                     /gene="fabZ"
                     /locus_tag="ACL3F5_000395"
     CDS             complement(20965..21387)
                     /gene="fabZ"
                     /locus_tag="ACL3F5_000395"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0514257.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(21384..21869)
                     /gene="accB"
                     /locus_tag="ACL3F5_000396"
     CDS             complement(21384..21869)
                     /gene="accB"
                     /locus_tag="ACL3F5_000396"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0514258.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21872..23107)
                     /gene="fabF"
                     /locus_tag="ACL3F5_000397"
     CDS             complement(21872..23107)
                     /gene="fabF"
                     /locus_tag="ACL3F5_000397"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0514259.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23129..23860)
                     /gene="fabG"
                     /locus_tag="ACL3F5_000398"
     CDS             complement(23129..23860)
                     /gene="fabG"
                     /locus_tag="ACL3F5_000398"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0514260.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(23894..24814)
                     /gene="fabD"
                     /locus_tag="ACL3F5_000399"
     CDS             complement(23894..24814)
                     /gene="fabD"
                     /locus_tag="ACL3F5_000399"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0514261.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24807..25781)
                     /gene="fabK"
                     /locus_tag="ACL3F5_000400"
     CDS             complement(24807..25781)
                     /gene="fabK"
                     /locus_tag="ACL3F5_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0514262.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25900..26124)
                     /locus_tag="ACL3F5_000401"
     CDS             complement(25900..26124)
                     /locus_tag="ACL3F5_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0514263.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26184..27158)
                     /locus_tag="ACL3F5_000402"
     CDS             complement(26184..27158)
                     /locus_tag="ACL3F5_000402"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0514264.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27158..27592)
                     /locus_tag="ACL3F5_000403"
     CDS             complement(27158..27592)
                     /locus_tag="ACL3F5_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0514265.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27686..28471)
                     /locus_tag="ACL3F5_000404"
     CDS             complement(27686..28471)
                     /locus_tag="ACL3F5_000404"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0514266.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28840..30204
                     /locus_tag="ACL3F5_000405"
     CDS             28840..30204
                     /locus_tag="ACL3F5_000405"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0514267.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAADSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRELTPIKEEEILRQLVQKTKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            30207..30578
                     /locus_tag="ACL3F5_000406"
     CDS             30207..30578
                     /locus_tag="ACL3F5_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0514268.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30792..32066
                     /gene="serS"
                     /locus_tag="ACL3F5_000407"
     CDS             30792..32066
                     /gene="serS"
                     /locus_tag="ACL3F5_000407"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0514269.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQSRRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32091..32990)
                     /locus_tag="ACL3F5_000408"
     CDS             complement(32091..32990)
                     /locus_tag="ACL3F5_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0514270.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33100..33648)
                     /locus_tag="ACL3F5_000409"
     CDS             complement(33100..33648)
                     /locus_tag="ACL3F5_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0514271.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33866..35188)
                     /locus_tag="ACL3F5_000410"
     CDS             complement(33866..35188)
                     /locus_tag="ACL3F5_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0514272.1"
                     /translation="MLELLKSIDAFTWGPPLLILLVGTGVYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(35279..35367)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(35530..37866)
                     /locus_tag="ACL3F5_000411"
     CDS             complement(35530..37866)
                     /locus_tag="ACL3F5_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0514273.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37970..38518)
                     /locus_tag="ACL3F5_000412"
     CDS             complement(37970..38518)
                     /locus_tag="ACL3F5_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0514274.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(38515..38817)
                     /gene="zapA"
                     /locus_tag="ACL3F5_000413"
     CDS             complement(38515..38817)
                     /gene="zapA"
                     /locus_tag="ACL3F5_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0514275.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38904..39785
                     /gene="rnhC"
                     /locus_tag="ACL3F5_000414"
     CDS             38904..39785
                     /gene="rnhC"
                     /locus_tag="ACL3F5_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0514276.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            39789..40403
                     /gene="lepB"
                     /locus_tag="ACL3F5_000415"
     CDS             39789..40403
                     /gene="lepB"
                     /locus_tag="ACL3F5_000415"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0514277.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40637..43003
                     /locus_tag="ACL3F5_000416"
     CDS             40637..43003
                     /locus_tag="ACL3F5_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0514278.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(43051..44334)
                     /gene="tig"
                     /locus_tag="ACL3F5_000417"
     CDS             complement(43051..44334)
                     /gene="tig"
                     /locus_tag="ACL3F5_000417"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0514279.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(44495..44887)
                     /locus_tag="ACL3F5_000418"
     CDS             complement(44495..44887)
                     /locus_tag="ACL3F5_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0514280.1"
                     /translation="MDSPKSLASYRVIGIIDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLESD"
     gene            complement(45189..45783)
                     /gene="cbpG"
                     /locus_tag="ACL3F5_000419"
                     /pseudo
     CDS             complement(45189..45783)
                     /gene="cbpG"
                     /locus_tag="ACL3F5_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(45864..46103)
                     /locus_tag="ACL3F5_000420"
     CDS             complement(45864..46103)
                     /locus_tag="ACL3F5_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514281.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(46253..47022)
                     /locus_tag="ACL3F5_000421"
                     /pseudo
     CDS             complement(46253..47022)
                     /locus_tag="ACL3F5_000421"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(47023..47655)
                     /locus_tag="ACL3F5_000422"
     CDS             complement(47023..47655)
                     /locus_tag="ACL3F5_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0514282.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(47669..48664)
                     /locus_tag="ACL3F5_000423"
     CDS             complement(47669..48664)
                     /locus_tag="ACL3F5_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0514283.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(48661..49359)
                     /gene="liaF"
                     /locus_tag="ACL3F5_000424"
     CDS             complement(48661..49359)
                     /gene="liaF"
                     /locus_tag="ACL3F5_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0514284.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSNYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(49436..50446)
                     /gene="fni"
                     /locus_tag="ACL3F5_000425"
     CDS             complement(49436..50446)
                     /gene="fni"
                     /locus_tag="ACL3F5_000425"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0514285.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEINLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(50430..51437)
                     /locus_tag="ACL3F5_000426"
     CDS             complement(50430..51437)
                     /locus_tag="ACL3F5_000426"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0514286.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGQLALIKDIPIYMRADIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFFAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKIAAWLKEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVTKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(51424..52377)
                     /gene="mvaD"
                     /locus_tag="ACL3F5_000427"
     CDS             complement(51424..52377)
                     /gene="mvaD"
                     /locus_tag="ACL3F5_000427"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0514287.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(52359..53237)
                     /gene="mvk"
                     /locus_tag="ACL3F5_000428"
     CDS             complement(52359..53237)
                     /gene="mvk"
                     /locus_tag="ACL3F5_000428"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0514288.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(53359..53688)
                     /locus_tag="ACL3F5_000429"
     CDS             complement(53359..53688)
                     /locus_tag="ACL3F5_000429"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0514289.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
BASE COUNT        15736 a        12348 c        10044 g        15708 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttgattgtat acgtttttac tacttttgtc aataaaaaaa catatattca acgaaaataa
      421 ttagttcaga attttcttac ttccttttta aatccgataa tatataggtt ttgctagcct
      481 ctacaccata aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat
      541 tattcaagtt cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta
      601 agaactgaag atgatagttc taacctttag aaatccaagc cttctctagc tcaaaaactc
      661 ctatctttct tcctcaataa atcatctgag agataggtat tccttatatc cttcaaattc
      721 atcactcctt tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat
      781 ccttaataga gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat
      841 ggtatatttg tcaacaaaaa gaaatcaaat cataccttat actcaatgaa aatcaaagag
      901 caaactagga agctagccgc aaattgctca aaacactgtt ttgaggtttc agatagagct
      961 aacgtggttt gaagagattt tcgaagagta ttaaagacag tatgactatg cttgtcaata
     1021 gataggaaat caaaatgaag gatggaaatc tgagccaaac atcataagtg ctataatgaa
     1081 cagaagtaag aattgcacga taagttttct aaaaccatag gaatcgtccc ctttcttcat
     1141 cttcattata gcacatatac atcagttgta caaataatat gatatttttt tattagtcct
     1201 cagacaagca tattataaag cgtttcatta ccatttaagt taatataagc tggatcaaaa
     1261 ccttccattc tacggatcaa acctgcataa tcatgcttat ctgccaaagc gatcccaatc
     1321 aatactgggc ctgttccctt gctagctcgt ttgatatact caaaacgtgt gatatcatca
     1381 tttggcccca ggatatcatt tacaaactca cgcaaagctc ctggacgctg tgggaaattg
     1441 accacaaagt aatgtttgat accatcataa atcaaggcac gctcttccat ttctggcata
     1501 cggttgatat cattatttcc tccagaaatg atacaacaaa tggttttccc cttaatatat
     1561 tcagctaaaa cctctaaaga ggcgatacta gccgctccag caggttctgc gactatccct
     1621 tgcttagagt aaaggtcaat caaggtttca gaaatcaatc cctcatcgac acctaccaaa
     1681 gtttgaatat gttgacgagt tgcttcatag gtcaactgac ctaccttttg cacagcaatc
     1741 ccatccgcaa atttatcaat ttccttgagt ttgactggac ctccagcctc aaaggcagct
     1801 ttcatggaac gcgctccatt cgcctctact ccgataacct caatctctgg acttgtttcc
     1861 ttgatatagg tagaaacccc ggcaatgaga ccgccaccac caacaggaac caagacagca
     1921 tcaaaatcaa tcgattcttt tcgagcttct tctaaaatct cataagcaac tgttccttga
     1981 cctgcttgaa catgagcatc atcaaaagga tcaataaagg tacgattttc agagactgta
     2041 aattcttgag ctgctttggc tgaggcatca aaggtatctc caactagttt aatagttaca
     2101 aaatccccac caaaaaagcg aacctgacca atcttttgtt gtggcgtagt aataggcata
     2161 aagatagtag caggaatttt catttcatta caagtatagg ctactccctg cgcatgattt
     2221 cccgcagaag cgcagactac cccacgttca cgttcttcct tgctgagctg ggaaatggca
     2281 taataggcac cacgaatttt aaaggagcga acacgctggg cattttcttt tttcaaataa
     2341 atcttagcac catacttctc cgataaataa tgatcgtaat ccagtggagt attcacaacc
     2401 acaccgttca agaccttgtg agccttgatt atatcttttg aacttaacat ataaaacctc
     2461 tttttctata aaaaacagtc actaatgact gttttttagt tattcatctc cgaaaacttc
     2521 agtaacactt tcatggtatt tatgagccat acgaatcgaa aactctttag gaagttcata
     2581 acgatttgtg gaaatccaat catataacca ttctaccaaa ctttcttcac tatcattacg
     2641 atggaagata aaatagttta aaatttcttt atattctaca tcattcaaat ccaacgtgtc
     2701 tacaaattga ctacgaggaa caaaattaga atctaatttt cttagttgat ctgtcaattc
     2761 tcccaattgt aaatccaact gaaaaaatag tttttgcagt tgcctatcag tttcatcaca
     2821 tcctgtcttg atagaaaaca aattggtaat attcatatga tttcaacccc taaataagta
     2881 catctaatat cccacgaata gctgaagcta aagttttcgc agtccagtca tttaaacccg
     2941 attctttcaa tccagatgca ataatttgct ctatttgata taaaccgcca tctatcgtct
     3001 catttattct gcgaagagga ccttcaatat aggataaagc ttctccgaat ctaacagctg
     3061 atttaggtcc taatgattta ccaactatat ttgttaatgt tttttatttc tcaaaatcca
     3121 tttcgctata taacgagcag atttagtcgc accagctctc tcaaacggag aatgaatttc
     3181 aagaccttct tctctagcta tttgtgccaa tttgaagaat tgttcaaagg tcatatgcaa
     3241 cctaccatct tcaaaattag catcatcata aatgttaatt acagcatttt catcatacga
     3301 ccaatctgct ttattttggt ctgctagcac tattaccgac ggtgtaatta cattatacaa
     3361 ctagaaccaa taataacgat gcaatttttc tcataatctt tttcataaaa tcatctccag
     3421 cgctatatat ttctaattag ttatagattt tgaatgcatc atcgtcgttt ttaccaacaa
     3481 atggcattgc tttacgcaat tctgcaccaa ctttttcaat ttcaaggtta gctgcttgtt
     3541 cacggtaagc agtcaatttt ggacgtccag ctttatagtc atttacaaag tcatttgcaa
     3601 atttaccatt ttggatgtct gccaagacag ccttcatatt ttctttaact tgttcagtga
     3661 ttacacgtgg acctgataca tagtcaccgt attcagcagt gtttgaaata gattgacgca
     3721 ttttcttgaa tccaccttcg tagatcaagt caacgatcaa tttcatttcg tgaagaactt
     3781 caaagtaagc caattctgga gcgtaacctg cttctgtcaa gacttcgaaa cctgcttcga
     3841 taagggcagt caaaccacca caaagtacag cttgttcacc aaacaaatct tcttcagttt
     3901 cttctttgta agttgtttca agaagaccta cacgagccgc tccaacacct ttacaccagt
     3961 ccatagcaat gtttttagca tttcctgttg catcttggta tactgcataa agagctggaa
     4021 caccaaatcc ttcttcgtaa gtacgacgta ccaagtgtcc cggtccttta ggagcacaca
     4081 tgaagacatc tacatccgca ggaactttga taaattcaaa gtggatgttg aaaccatggg
     4141 caaatccaac tgcgtttcca gcttccaagt ttggagcgat ttctgcttcg tacaattctt
     4201 gttgaatttc gtctggcgcc aagatcatga taacatcagc caacttagta gcttctacta
     4261 ctgtgtaagt atcaaatcca tcttcttttg ctttatcaaa agatttacct ggacgtacac
     4321 cgataataac gtcacgacct gaatcacgca agttttgagc atgcgcatgt ccttgtgaac
     4381 cataaccgat aacggcgatt tttttaccgt caagtgctgc tactttaaca tctttttcat
     4441 attccatttg aactgtcata gcttttctct cttttctatt atttattgcc ttttaggctg
     4501 gtttaataaa tttaagttgg atttttaatc gcgggtaaat ccagttgcac ccgttcgagc
     4561 aatattgcga ataccgtatg ggcgaatgac tcgcaatagg gcttcgctct tttctgcatt
     4621 tcccgtcatc tgaatggtaa tcgagcttgg cgctacgtct accactgttg cacggaaagg
     4681 ttgaataatc gctaaaatct cagctctctt ctcagctggc gctgacatct taaccaaaat
     4741 cacctcgcgc tccaaatgag gcttgtctgt aatatctcga atgcgaatca catcaatctg
     4801 acgattgagc tgtttgatga tttgctccac ttcatcatga gaagcaacat caataataat
     4861 agtgatacgc gatacattcg gatcttctgt tgctccaaca gagatgcttt caatattaac
     4921 ctgacgacga gataggacac ctgtaaagcg attgaggact cctgaacgat tttgtagttt
     4981 tgctgttaac attctacgca tggaactgca cccccaacat ctcatgatta ctcttaccag
     5041 ccggtaccat tggtaacacc tgttccttac gagaaatatc tacctcaatt agcataggaa
     5101 catcctcagt gatgacttca aggtcttgag ccaaggtctc aggattgtca aacttatagt
     5161 ttttaatacc ataagcctgc gccatcaatt ggaaatcagg aagggtatca aagaccgact
     5221 ctgatgttct gccttcatag aaggattcct gccactggcg aaccattcca agtgaatgat
     5281 tgttcagcat aaccaccttg attggcacct tgtaaatatt caaaatagcc aactcctggt
     5341 tggtcatttg gaaaccacca tccccaacaa acaagactac ttccttatct gggttagcaa
     5401 ttttagcacc gattgctgct ggaattccaa agcccattgt tcccaaacca cctgaagtca
     5461 ctaactgacg ctcattttgg tagggataat actgagctgt ccacatttgg tgttgaccaa
     5521 cgtctgttac cacaatggca tctccattcg tcaattcacc aattcgttca ataactgctt
     5581 gcggttgaac cacacgctct ttcttgtcat aagaacgaac acgattcttg tctttagtga
     5641 ctttctcaat ccacttttca gtattgttgt gaactgttgg ttctgctagc aacatttgca
     5701 aggccttctt agcatctcca actacaggaa tgtctgcact gataatcttg ccaatctcag
     5761 ctgggtcaat atcaatgtgg gcaaccttag cattcttagc gaaagtctta ggattccccg
     5821 tcaaacggtc atcgaaacga gaaccaatac taatcataaa gtccgcttcc gtcatggcaa
     5881 tatttgctgc gaatgacccg tgcatgcctc ccattccaag aaagagtggg tgactcgttg
     5941 caatcgttcc ttgtcccaaa agactggtta ccactggaat ttgatagcgt tctgcaaatt
     6001 catttagttc cgtagcagcc tcagcataac taattccacc accagctaac aagactggct
     6061 ttttagcctt ggacaattgc ttcaagattt tcttgatttg catatcattc ggctcaagag
     6121 tcggctgata acttggtaaa ttcacttctg gtgaataaat gaagtctgtt tctaaagcag
     6181 atatgtcttt tggtaggtca attacaactg gccctggacg gcctgtagtt gcgatatgga
     6241 cagcttccgt aatgatacgc ggaatatcag ctgtctcacg aacttggtaa ttgtacttag
     6301 tgattggcat ggtaattcct acgatgtctg cctcctgaaa ggcatccttc ccaatccctg
     6361 ctcgcgccac ctgacctgta aagaccaaaa ggggaacgct atcgctcata gcatccgcaa
     6421 tccctgtaat ggcatttgtt gctcctggtc cactagtgac gacggcaaca cccaactttc
     6481 cagttgattt ggcataacct tcagcttcat gcaaacaacc ttgctcatgg cgccctagaa
     6541 tgtggcgaat gcctttaaaa ttatatatcg catcataaaa aggcaaaacc gcaccaccag
     6601 gataaccaaa gatggtatca actcctaaat cacgaagtgt ttccaaaact aggtccgacc
     6661 ccgtcttagg agattctaaa ctgattttct ccattgttcc cctttctttc ctcttaaaaa
     6721 taacttgtta ctatcatacc attttttcaa aatttttcaa gataaaagaa gaaattttct
     6781 gaattttcta ttttaacgtt tatttatgaa tgttattttt gtttttatta aaaagatacc
     6841 gatttcattt actaaaaaag aaaaaagaac tgatttctca gtccttcatt aatcttattc
     6901 cacactaaat aggtatgggt aaacaggttg ttgaccttgg tgaatctcga cttcaacgtc
     6961 ttcgaattct tctacgattt cttgagcgat ttcattggca agttcttcgc ttccgtcttc
     7021 accgacatag aaggttacga tttcactatc ttcatccaac atatgtttca aggtttcagt
     7081 caatgtttgg tgcatatcag ggtttgacac aagaattttt ccatccacca tacctagatt
     7141 atcgttttca tggatttcta agccatcgat cgttgtatca cgcacggctg ttgtgacgct
     7201 tccgctaacg acatcgctaa gagcagctgt catacgctct tggttttctt caatggactt
     7261 gcttggatca aaggcaagaa gacttgtcat accttgagga agagtgcgag cctctaccac
     7321 tactgctggt tgctccaaaa cttctgccgc agattgagct gccatgaaga tgttcttgtt
     7381 gtttggcaag aagatgatgt tacgggcatt gacctgttca acagccttga taaagtcttc
     7441 tgttgaaggg ttcatggttt gaccgccttc gataacataa tccacgcctt gagaacagaa
     7501 gatatctgct agacctttac cagccaccac agcaatcaaa gcatactctt tttcttcagc
     7561 cgacttgata acttgagtag cttctttctc aacctgtgct tcgtgttggt tacgcatatt
     7621 gtcaactttt accttgacca agctaccata tttgagacct tcttgcataa caagtcctgg
     7681 atcttctgta tgaacatgga ctttgacaat ttcatcatcg ttaacaacga ggagagaatc
     7741 cccaagctca tccaagtagt tacggaattc atcgtagtca aaatctttag cataggttgg
     7801 accttgctta agagctacca tgatttcagt acagtaacca aacgtgatgt cctcagtcgc
     7861 tacgtgacca gctacagact tatgatgctc tacattgatc atctcactca tgttggcagg
     7921 agtcgctaca aagtcctcag atgcaatata ttcgccagta agggctgaaa ggaaaccttc
     7981 gtagatgaag accaatcctt gaccacctga gtccacaacg ccaacttctt tcaatactgg
     8041 aagcatgtct ggtgttttag ctagagctgt tttagcacct tccaaggctg cgcgcatgac
     8101 ttcaacagtg tcatctgttt gctcagcttt tttcttagca ccgatagcag ctccacgaga
     8161 aactgtcaaa atcgttcctt caacaggttt catcactgcc ttataggcaa cttccacacc
     8221 tgattggaag gccagagcca agtcttgacc tgttaactcg tctttatcct tgatagcttg
     8281 ggaaaatcca cggaaaagct gagacgtaat cactcctgag ttcccacgcg cacccatcaa
     8341 aagccctttg gcaagaatgc tcgctacttc tccaactgta gaagctggct tgtctgcaac
     8401 ttctttagca ccattttcaa tggtcattcc catatttgtc ccagtatctc catctggaac
     8461 tggaaagacg tttaatgaat tgacatattc agcttgctta ttcaagcgag ttgatgcagc
     8521 ctgcaccatt tcttgaaata agctagtagt aatttttgac acggttattc tcctacaact
     8581 ttgatatttt gaatgtagac atttacagtc tgagcagtaa ttccaagctg gttttccaag
     8641 ctaaaggcaa cacgctcttg aatgtttttt gacacttcac taatctttgt tccgtagctt
     8701 aacacggtat atacatcaac tgcaatactg ccatcttcgg ctgcctttac gacgacacct
     8761 ttagaataat tttccttacc tagcagggct tggaaattat ctttgagggc atttttacta
     8821 gccataccga ccacaccaaa aatctcagtt gctgctccac ctacgacggt tgcaatcact
     8881 tcatctgtta gttcgatttg accatctttt gtattaattt ttacagtcat cctttttacc
     8941 tcaactagtt gatactctat tttatcatat ttcagcccaa gtgtaaaagc agaatgatgt
     9001 atcagcggat atttactcta tttttcaaac gatgttatac ccacaataaa agaaaaaaga
     9061 ccctaaggtc tcctttgctt ttattattaa acgcgttcaa ctttacctga tttcaaagca
     9121 cgagctgaag cccaaacttt tttaggttta ccatcgataa gaacagtaac tttttgaagg
     9181 tttggtttta cggcacgttt tgtttggttc atcgcgtgtg aacggttgtt tcctgataca
     9241 gtcttacgac ctgtaaagta acatacttta gccattgtgt tttcctccta ttagatctaa
     9301 tatagcggat gtgctagcac cacataccgt actatgttat cacactttct tgttttttgc
     9361 aagggaattg gaagattttt tatttgtgtc ttaaatcagg tcttgcgtga cattttctgc
     9421 tctccacatg ccattgttga ttaacagaac accagaatta aaattatgtg tataaaaatc
     9481 atctctaact gcagctaagg gtatagccgt caagtccaaa tcccacagct catctatcga
     9541 ttttcttaca acaatatctg aatccaaata cagtacacga gactcgctta catactttgg
     9601 aataaaatac ctaaaaaagc cgcatatgaa agtccctcaa aggggagacg ataacctttc
     9661 agaatactac tgtcaatcta aacattcaca atctcactat tcaaagtctc tagtcttttt
     9721 tccattaatt ggaaccattc tcgcggaagg tcatcattaa aaacataaaa cttaagatta
     9781 taatgatgaa cacaaagaga ttttattgtt gtttcaactt tatccatata agcattatct
     9841 gcacctaaga caatcgcttt tttctcttct ttcacttttt atctcatttc tttttattcc
     9901 catcatatgt ttctacgtaa ccattatttt cgcctattcg ttcgtaaaac cataccagtg
     9961 gagattttag atgaagtccc attacggttt acaattttta cattacgaca cagagtttta
    10021 caaatcgatt tcatttgcca aacgtagtta gtaaggcagt tagctaggct acctactttc
    10081 tgctacgacg gaaaaatcca caaatcaata ccattcgtgg atttttccta gtgaagcgtt
    10141 taggtaagcc gccatagcgg ttaccgatta ttagattacg acacggagtt tggcaaatcg
    10201 attctatttg ccaaacgtag ttagtgaggc agttagctag ttcgccaaat agcgactagc
    10261 gtccaacaat ttggaacttt agttccaatt gttggtactg agtcacatct tctcctctaa
    10321 ctctacgtct ggatacttgt ccgcaaacca gcggagggca aagtcatttt caaagagaaa
    10381 gactggttgg tcaaaacggt ctttggctaa gatattgcga cttgacgaca tccgttcatc
    10441 caagtcctca ggcttgatcc aacgaacggt ctttttaccc attgggctca tgaccacttc
    10501 cgcattgtat tcgccttcca tacggtgttt aaagacttca aactggagtt gaccaacagc
    10561 tcccagcatg tactcacctg tttggtaatt cttataaagc tgaacggctc cttcttgcac
    10621 caattgctca atccccttgt ggaaggattt ttgcttcata acattcttag cagaaacttt
    10681 catgaaaatt tcaggagtaa aggttggcaa tggttcaaat tcaaacttgt tttttccaac
    10741 cgtcaaggta tccccaacct gataagtacc ggtatcgtaa accccgataa tatcacctgc
    10801 cacggcattg gtcacattct cacgactctc cgccataaac tgggtaacat tagatagttt
    10861 agccccctta ccagtacgag ggagattgac actcatgccg cgctcaaatt cgcctgatac
    10921 gatacggaca aaggcaatac ggtcacggtg acgaggatcc atgttggctt ggattttaaa
    10981 gacaaagcct gagaaatcct tgtcataagg atccacaatt tcaccatctg ttttcttgtg
    11041 accatgtggt tctggagcaa acttgaggaa gatttcaagg aaggtctgca caccaaagtt
    11101 tgtcagggct gaaccgaaaa agacaggcgt caattctcca gccagaatag cttcctctga
    11161 aaactcattc ccagcttcat ttaaaagctc aatgtcatcc ttgacttgct cgtagaaagg
    11221 attgctacca aaaagtttgt ctccatcttc taggctagca aaacgctcat cccctttata
    11281 aagttctaaa cgttggttat agaggtcata caagccctca aaggctttcc ccatcccgat
    11341 aggccagttc atagggtagc tagcaatgcc caagatttct tccaattctt gcaagagttc
    11401 caaaggctca cgaccgtcac ggtccagctt gttcataaag gtaaagactg gaatgccacg
    11461 atgtttcaca acctcaaaca atttcttggt ttgagcctcg atccccttgg cagagtccac
    11521 gaccatgacc gcagcatcca ccgccatcaa ggtacgatag gtatcttctg agaagtcctc
    11581 gtgccctggc gtgtctaaga tattcacgcg cttgccgtcg tagtcaaatt gcataacaga
    11641 tgaagtaaca gaaatcccac gttgcttctc gatatccatc cagtcagatt tagcaaaagt
    11701 ccctgttttc ttccctttta ccgtaccagc ctcacgaatc tcacccccaa agtagagtaa
    11761 ctgctcagtg atggttgttt tccccgcgtc cgggtgggag ataatggcaa aggtacgacg
    11821 tttcttaatt tcttcttgaa tattcataag ttctctttct ttgattctct atttttcttg
    11881 tttcaatagc tgagaatgat ttttacattg gattttacca ttcctttcaa cactccatta
    11941 tatcggattt tagcattttt ttcaatttct atttcttttc acttccccct cccttattta
    12001 taggaaaata tggtaaaata gaacagacta aaaatcatca tttcacgaaa ggatgcaaga
    12061 tgaaaattac gcaagaagag gtaacacacg ttgccaatct ttcaaaatta agattctctg
    12121 aagaagaaac tgctgccttt gcgaccacct tgtctaagat tgttgacatg gttgaattgc
    12181 tgggcgaagt tgacacaact ggtgtcgcac ctactacgac tatggctgac cgcaagactg
    12241 tactccgccc tgatgtggcc gaagaaggaa cagaccgtga tcgcttgttt aaaaacgtac
    12301 ctgaaaaaga caactactat atcaaggtgc cagctatcct agacgatgga ggagatgcct
    12361 aatgactttt aacaataaaa ctattgaaga gttgcacaat ctccttgtct ctaaggaaat
    12421 ttctgcaaca gaattgaccc aaacaacact tgaaaatatc aagtctcgtg aggaagccct
    12481 caattcattt gtcaccatcg ctgaggagca agctcttgtt caagctaaag ccattgatga
    12541 agctggaatt gatgctgaca atgtcctttc aggaattcca cttgctgtta aggataacat
    12601 ctctacagac ggtattctca caactgctgc ctcaaaaatg ctctacaact atgagccaat
    12661 ctttgatgcg acagctgttg ccaatgcaaa aaccaaaggc atgattgtcg ttggaaagac
    12721 caacatggac gaatttgcta tgggtggttc aggtgaaact tcacactacg gagcaactaa
    12781 aaacgcttgg gaccacagca aggttcctgg tgggtcatca agtggttctg ccgcagctgt
    12841 agcctcagga caagttcgct tgtcacttgg ttctgatact ggtggttcca tccgccaacc
    12901 tgctgccttc aacggaatcg ttggtctcaa accaacctac ggaacagttt cacgtttcgg
    12961 tctcattgcc tttggtagct cattagacca gattggacct tttgctccta ctgttaagga
    13021 aaatgccctc ttgctcaacg ctattgccag cgaagatgct aaagactcta cttctgctcc
    13081 tgtccgcatc gccgacttta cttcaaaaat cggccaagac atcaagggta tgaaaatcgc
    13141 tttgcctaag gaatacctcg gtgaaggaat taacccagag gttaaggaaa ccattctaaa
    13201 tgccgctaaa cactttgaaa aattgggtgc tattgtcgaa gaagtcagcc ttcctcactc
    13261 taaatacgga gttgccgtat actacatcat cgcttcatca gaagcttcat caaacttgca
    13321 acgcttcgac ggtatccgtt acggctatcg cgcagaagat gcaaccaacc ttgatgaaat
    13381 ctatgtaaac agccgaagcc aaggttttgg tgaagaggta aaacgtcgta tcatgctggg
    13441 tactttcagt ctttcatcag gttactatga tgcctactac aaaaaggctg gtcaagtccg
    13501 taccctcatc attcaagatt tcgaaaaagt cttcgcggat tacgatttga ttttgggtcc
    13561 aactgctcca agtgttgcct atgacttgga ttctctcaac catgacccag ttgccatgta
    13621 cttagccgac ctattgacca tacctgtaaa cttggcagga ctgcctggaa tttcgattcc
    13681 tgctggattc tctcaaggtc tacctgtcgg actccaattg attggtccca agtactctga
    13741 ggaaaccatt taccaagctg ctgctgcttt tgaagcaaca acagactacc acaaacaaca
    13801 acccgtgatt tttggaggtg acaactaatg aactttgaaa cagtcatcgg acttgaagtc
    13861 cacgtagagc tcaacaccaa ttcaaaaatc ttctcaccta cttctgccca cttcggaaat
    13921 gatcaaaatg ccaacactaa cgtgattgac tggtctttcc caggagttct gccagttctc
    13981 aataaagggg ttgttgatgc cggtatcaag gctgctcttg ccctcaacat ggacatccac
    14041 aaaaaaatgc actttgaccg caagaactac ttctaccctg ataatcccaa agcctaccaa
    14101 atttctcagt ttgatgagcc aatcggttat aacggctgga ttgaagtcga gctagaagac
    14161 ggtacgacca agaaaattgg tatcgaacgc gcccacttag aggaagacgc tggtaaaaac
    14221 acccacggta cagacggcta ctcttacgtt gaccttaacc gccaaggggt acctttgatt
    14281 gagattgtat ctgaagccga tatgcgttcg ccagaggagg cctatgctta tctgacagca
    14341 ctcaaggaag ttatccagta tgctggcatt tctgacgtta agatggagga aggttcgatg
    14401 cgtgtggatg ccaacatctc ccttcgtcct tatggtcaag agaaattcgg taccaagact
    14461 gaattgaaga acctcaactc cttctcaaac gttcgcaagg ggcttgaata cgaagtccaa
    14521 cgccaggctg aaattcttcg ctcaggtggt caaatccgcc aagaaacacg ccgttacgat
    14581 gaagcgaata aagcaaccat cctcatgcgt gtcaaggaag gggctgctga ctaccgctac
    14641 ttcccagaac cagacctacc cctctttgaa atttctgacg agtggattga ggaaatgcgg
    14701 actgagttgc cagagtttcc aaaagaacgt cgtgcgcgtt atgtatctga ccttggttta
    14761 tcagactacg atgctagtca gttgactgct aataaagtca cttctgactt ctttgaaaaa
    14821 gctgttgccc taggtggtga tgccaaacaa gtctctaact ggctccaagg ggaagtcgct
    14881 cagttcttga atgctgaagg taaaacactg gaacaaatcg aattgacacc agaaaacttg
    14941 gttgaaatga ttgccatcat cgaagacggt actatttcat ctaagattgc caagaaagtc
    15001 tttgtccatc tagctaaaaa tggcggtggc gcgcgtgaat acgtggaaaa agcaggtatg
    15061 gttcaaattt cagatccagc tatcttgatc ccaatcatcc accaagtctt tgccgataac
    15121 gaagctgctg ttgccgactt caagtcaggc aaacgtaacg ccgacaaggc ctttacagga
    15181 ttccttatga aggcaaccaa aggccaagcc aacccacaag ttgcccttaa actacttgca
    15241 caggaattgg cgaagttgaa agaaaactag acagaacaaa accagcccta aggttggttt
    15301 tttcttctct accaactccc aataactatt ttggctttat ttccagagta ttttatggta
    15361 aaatgaagag taataatatt tattaaagag gtaaaaacat gattgaagca agtaaattaa
    15421 aagctggtat gacctttgaa acagctgacg gcaaattgat tcgcgttttg gaagctagtc
    15481 accacaaacc aggtaaagga aacacgatca tgcgtatgaa attgcgtgat gtccgtactg
    15541 gttctacatt tgacacaagc taccgtccag aggaaaaatt tgaacaagct attatcgaga
    15601 ctgtcccagc tcaatacttg tacaaaatgg atgacacagc atacttcatg aatacagaaa
    15661 cttacgacca atacgaaatc cctgtagtca atgttgaaaa cgaattgctt tacatccttg
    15721 aaaactctga tgtgaaaatc caattctacg gaactgaagt gatcggtgtc accgttccta
    15781 ctactgttga gttgacagtt gctgaaactc aaccatctat caaaggtgct actgttacag
    15841 gttctggtaa accagcaacg atggaaactg gacttgtcgt aaacgttcca gacttcatcg
    15901 aagcaggaca aaaactcgtt atcaacactg cagaaggaac ttacgtttct cgtgcctaat
    15961 ctctagaaag aggtcattct atgggaattg aagaacaact tggcgaaatc gttatcgccc
    16021 cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa ggtagagggt gttcactctt
    16081 tttcaaacag atcagtgtct gatacccttt caaaactttc actcggccgt ggcatttatc
    16141 ttaaaaacgt ggacgaagaa ctcacagcag atatctatct ctaccttgag tacggagtaa
    16201 aagttcctaa ggtagcggtt gctatccaga aagctgtcaa agatgccgtc cgtaatatgg
    16261 ctgatgtaga actcgctgct atcaatattc acgttgcagg tatcgtccca gataaaacac
    16321 caaaaccaga attgaaagat ctatttgacg aggacttcct caatgactag tccactatta
    16381 gaatctagac gccaactccg taaatgcgct tttcaagctc tcatgagcct tgagttcggt
    16441 acggatgtcg aaactgcttg tcgtttcgcc tatactcatg atcgtgaaga tacggatgta
    16501 caacttccag cctttttgat agacctcgtt tctggtgttc aagctaaaaa ggaagaacta
    16561 gataagcaaa tcactcagca tttaaaagca ggttggacca ttgaacgctt aacgctcgtg
    16621 gagagaaacc tccttcgctt gggagtcttt gaaatcactt catttgacac tcctcagctg
    16681 gttgctgtta atgaagctat cgagcttgca aaggacttct ccgatcaaaa atctgcccgt
    16741 tttatcaatg gactgctcag ccagtttgta acagaagaac aataaaaaga aaaagtgttt
    16801 gatagatatc aaacactttt ttctttgcct cccactatct aaaaaaatga taatagatat
    16861 aattgtaaac aaaaatccag ataggttttg catgattgag aaagttaaaa aaactatggc
    16921 agagaatcgt taatctcaga ttgtcggtag aacgataaac aagggcaaaa aagaaaccaa
    16981 tcagactata atataataaa ctaattggat ctctgtgaga tagtatcaaa tggctaatcc
    17041 caaagatgat agcagatagg ataacatcca aatagtactt ggactaggga aagaaggtat
    17101 tcataaaata ccctctatca agagtctcct caaaaacagg accgatgatt acaggcagga
    17161 caaaagataa gatagtcgat aaaaaggttg gttgtccatt tgaaaaaagc acggtaaaat
    17221 actcatcatg aatattccta tgattaatca aatgagcata gcgtgcccaa aaattaccga
    17281 gaatctgata aaccacataa gttgcaaata agtagaagac aaatgaccag ttccagctct
    17341 ttttctcaaa gataaagagc atctttttct tttttaacct ccaaattaat agaaggaaac
    17401 ttcccactaa tcccattgtt aaaataagag aatagacatc agctcctaac cctaaaatga
    17461 tcgtcacata caatccaatt gtttgtggta aataggtaga tagtaaaata ataagcaaaa
    17521 atattccaaa ttgtcttagt ttttttgtgt ttctcatcgt acttttttga aagattaccc
    17581 tgctcggaag ccgtacttcc aagcatctat ataagaatta agtgcccctt gcctcatata
    17641 gggagcaaat tctctataat ataaccatct actatatcca tcttcccaaa cagcaagacc
    17701 acctgaagtt tgctccaagt cctcagttga aagaactgta aatgtatttg tacctgtcat
    17761 tgcaagtacc ttcttaaaat agattgttgt aggctcacat ttatagtata tttctttttt
    17821 tgtctatttt atagcccatc tcctcaactg gcaatttttc gacctgaatt acatttttcc
    17881 ataaaaaatg agacctttct agtctcattt agtcattctt agtattttct aaatcgttga
    17941 tagcgttctt ccagcaactc ttctagcggt ttttgtgaaa gtctagccag ctccgtttgg
    18001 agttcttttt tgacactctt aatcagttct ttactagaaa gtcctatttc agaaatcacc
    18061 ttatccacca cgtccatttc taacagttca tgcgaagtga ttttcatcag ttctgctgct
    18121 tccatggcgc gagtaccgtc cttccataaa atggaagcaa agccttctgg actgagaatg
    18181 gcatagatag aattttccag catccagaca cggtccgcga cagctagagc cagagccccg
    18241 cctgaaccac cttcaccgat aataatggcg ataataggaa ctttcaggtc actcatttcc
    18301 atgagattgc gagcgatagc ttccccttga ccacgttctt ctgctccgac accaggataa
    18361 gcacctgctg tattaataaa ggtcacaact ggacggccaa atttctcagc ctgtttcatc
    18421 aaccgcagtg cctttcggta gccttctgga tgtggttggc caaaattccg tttgaggttg
    18481 tcttgcaaac tcttgccttt ttggatacca acaactgtta cagcttggtc tccaagccaa
    18541 ccaataccac caacaactgc accatcatca cgaaaagaac ggtcaccatg taattggata
    18601 aattcatcaa aaatgcctgt cgcaaagtcc aaggttgtca agcgactctg ctcacgcgct
    18661 tctctgacta tttttgcaat attcatctag gactccctcc atgcaatctg actaggctag
    18721 caatcgtatc tggtaagtct cttcttttga caatagcatc cacaaagcca tgttctaata
    18781 ggaattctgc cttttggaaa tcctcaggca agctttcacg aaccgtattt tcaatcacac
    18841 gacgcccagc aaaaccaacc aagctctgtg gttcagccag aatgatatcg ccttccatag
    18901 cgaaagaagc tgtcacacca ccagtcgttg gatctgtcaa aatggtcagg taaaagagac
    18961 cagcatttga atgacgttta accgccgcag agatcttagc catctgcatg agactcatga
    19021 ttccttcctg catacgggct ccaccagagg ctgtgaatag gacaactggc aatttttcga
    19081 cagtcgcata ctcaaacaaa cgagtgattt tttcacctac aaccgtaccc atagaagcca
    19141 tgataaagtt agaatccata atcccaagag ccacagtctg acctttaata agagcagttc
    19201 ctgtcacaac ggcttcatgc agacctgttt tttcacgcat agatgccagt ttcttttggt
    19261 aaccagggaa atgcaaggga tccttgcttt caatccctgt aaacaattct ttgaaggttc
    19321 ccatatcaat cgtcaaagcc aagcgttctt gggcagaaat acgaaaggta tagctacagt
    19381 gcggacagat acgttcactt cccagatcct tctgatagat ggtatgctta cagcctggac
    19441 actgggaaaa taattcatct ggaacctctg gcttagcttg aggtttttcc ctaaccgaac
    19501 gattgggatt gattcgaata tacttatctt ttttactaaa tagagccatt gattcccctt
    19561 ttcggtttaa actcttaaag tcattttatt ctttttcttg atatttaggt aaaaaggttt
    19621 ccatcaagaa ggaagtatca taatccccag caatgacatt gcgatctgaa atgaggtcaa
    19681 gctggaaatc tgcattggtc tgcactcctt caatctctaa ttcatagagg gcacgttgca
    19741 ttttcatcaa ggcgtcaaaa cgattttcgc cgtgtactat gattttggca atcatactat
    19801 cataataagg cggaatggta taacctggat aaactgctga atccacgcgc aagccaactc
    19861 caccacttgg cagatagaga ttagtaatct tacctggact tggagcaaag ttaaaggctg
    19921 ggttttctgc attgatacga cactcgatgg catgaccgcg taggacaata tcttcttgct
    19981 taacagacaa aggctgacct gccgcaatgc aaatctgttc cttaacgata tcaacacctg
    20041 aaacaaactc tgttactgga tgttctacct gaacacgagt attcatctcc atgaaataga
    20101 aattgctact tgcttcatca agaagaaatt caatggttcc tgcattctca tagccaacaa
    20161 actctgccgc tcgaacagca gcagcaccta tttcatgacg cagcgttttt ccgattgcaa
    20221 tcgagggact ttcttccaaa accttttggt tattcctttg aagagaacaa tcccgctcac
    20281 ccaagtgaat cacatgtcca tgctcatcac ctaggatttg aacctcaatg tgccgagctg
    20341 gatagataac ccgttctatg tacatggcac cattgccata attggccttg gcctcactag
    20401 aggcagtttc aaaggcagaa acgaggtcat ctggtttttc aaccttacga atccctttac
    20461 cacctccacc tgctgaagcc ttgagcataa caggatagcc aattttttca gcaacaatca
    20521 aagcttcttc agagttatgc acttctccat ctgaacctgg tataacaggc acacctgctt
    20581 taatcatctg agcacgcgca ttgatcttat cccccatcat atccataaca tgaccagatg
    20641 gaccgataaa cttgatacct acttcttcac acatggtcgc aaatttggaa ttttcactga
    20701 gaaatccaaa accagggtga atagcttctg cctcagtcaa gactgcagct gatagaactg
    20761 cattaatatt gagataagac tctgttgcct tgccaggacc aatacaaact gcttcatctg
    20821 ccaaaagcgt atgaagagct tccttatcag cagttgaata aaccgctacc gtcgcaatcc
    20881 ccaattcacg tgccgcacgg ataatacgaa ccgcaatttc accacgattg gcaattaaaa
    20941 tttttcgaaa catggagaac ctccttagtt cccaattgca aaagtaagga taccactggc
    21001 tgcaagcttg ccatccactt cagcctttgc ttcaaccaca gctatggtgc cacgacgttt
    21061 tacaaaagtc gctgtcataa ccaattggtc gcctggtaca acttgcttct tgaacttaac
    21121 cttgtccata ccagcgtaaa agaccagttt tcctttattt tcaggttttg ataactccaa
    21181 cacaccagca gtttgcgcca aggcttccat aatcagaaca cctggcataa ctgggtattg
    21241 aggaaagtgg ccgttaaaga aaggttcgtt aatggtcaca tttttgatag caacaatggt
    21301 atcctcgctc acttccaaga cacggtccac tagaagcata ggataacggt ggggaagagc
    21361 ttctttgatt ccttgaatat cgatcatttg atacgtacca atcctttacc aaactcaacc
    21421 atttcttcgt tagagacgag aatttccgtt accacaccat ccttaggagc tgggatttca
    21481 ttcatgactt tcatggcttc gataattacc aatgtttgac cttttttgac actatcacca
    21541 actgtaacga aggcaggttt atctggtcca gcagccaagt aaaccactcc aacaagtgga
    21601 ctctctacaa gatttccctc actagccaca cttgcttcag ctggagctgg aacttcttct
    21661 gctacagtct ctgctggagc agatgtagga gctactggac tcggtgttgc tagaacgggt
    21721 gctggagcga cttgagttgc aacttcaggc acaggtctcg cttcattctt gctaaactgc
    21781 aactcatccg tcccattttt ataagaaaat tctctcaaac ttgactggtc aaattgagtc
    21841 atcaagtctt taatatcgtt taaattcata cttatctatt ctcccaacgt ttgaaagcaa
    21901 gaactgcatt gtggcctcca aaaccaaaag tatttgaaat agcgtatgga atttctttct
    21961 ccaagccttg tccataaacg acattagctt cgatataatc tgatacttca cttgtcccag
    22021 ctgtcattgg tacaaagtta tgacgcatag cttcgatggt gacgatagct tctactgcac
    22081 ccgcagcccc cagcaaatgt cctgtaaaag acttggttga tgatacaggt acttccttac
    22141 caagaacagc tacgatagca ccactttctc ctttttcatt ggcaggagtt gacgttccgt
    22201 gagcattgac ataggctact tgctctggag aaatctcagc ttcttccaag gctagtttga
    22261 tggccttgat agctccctga ccttctggat gtggagaagt catgtggtag gcatcacaag
    22321 tatttccgta accaaccact tcagccagga tagtagctcc acgtttttca gcgtgttcaa
    22381 gactttctag aaccaacatc cctgaacctt cacccataac aaacccattg cgatccttat
    22441 caaatgggat cgaagcacga gttggatcct ctgtagtaga gagagctgtt aaggcttgga
    22501 aaccagcgat ggcaaaaggt gtgatagaag cttctgttcc tcccaccaac atcacatctt
    22561 ggaaaccaaa cttaatggag cggaaggcat ccccaatcgc atcatttgat gaagagcagg
    22621 cagtattgat agatttacaa acaccgtttg caccaaaacg catggctaca ttcccagaag
    22681 ccatatttgg taaagctttt ggaagagtca ttggtttgac acgtttgggt cctttttcat
    22741 gaaggcgaag tacctgatct tcaatttcct tgattccacc aataccagat gcaacgataa
    22801 caccaaaacg atccctatta agagcctcta catcaagatt ggcatgattt acagcctctt
    22861 gggctgcata caaggcatat aaagaatagt tatcaaaacg gttggtatct ttttttacaa
    22921 agtatttatc gaacggaaaa tcttggattt ctgccgcatt atgcacatca aagtcactat
    22981 gatcaaattt tgtaatgcca ccaatgccga ttttcccagt tgctaaacta ttccaaaatt
    23041 cttctggtgt atttccgatt ggagatgtta ctccataacc tgttaccact actcgattta
    23101 gtttcattct tttcacctct agctttcgct acatacttaa gccaccatca atggcaacca
    23161 cttgaccagt tagataatct tggcctgcta aaaatactgt caaatctgca acctgctctg
    23221 cctgcccaaa ttctttcatc ggaatctgag ctagtgtagc ttccttaatc ttatctgata
    23281 agatagctgt catatcagac tcaatcattc ctggagcaat cacattgact cgtatattcc
    23341 gactagcgac ctcgcgtgcc acagacttgg taaagccaat caagccagcc ttagaagcag
    23401 catagttagc ttgaccaata ttccccatca aaccaacaac actagacata ttaatgatag
    23461 caccttctct ggctttcatc atcggtttca agactgattg tgtcatatta aaggcaccag
    23521 tcagattgac cttgagcact ttttcaaaat ctgcttctgt catcttgagc ataagagtat
    23581 cttgggtaat ccctgcattg ttgaccaaaa catctactga acccagttct gcaatagctt
    23641 gatcaatcat acgcttagcg tctgcaaaat ctgatacatc tcctgaaatg ggaaccacct
    23701 tgataccata gtttgaaaac tcagcgagca attcttctga gattgcccca cgactgttta
    23761 agacaatgtt ggctcctgct tgagcaaact tgtgggcgat ggcaagacca attccacgac
    23821 tcgaacctgt aataaagata tttttatgtt ctagtttcat ttttttcctt tcaaaacttc
    23881 tacttatttt agtctatttt tctaaaagtg ctactaaact cgcttgatct tccacatgag
    23941 ctaagtgagc agtttgatca atttttttaa caaaacctga caagactttc cccggtccaa
    24001 tctcgataaa gttgcttatg cctgcttctt gcatgacccc aatactttca tagaaacgaa
    24061 cgggttcctt gacctgacgc gtcaagagct gagcaatgtc ctctttttgc atcacagcag
    24121 cttctgtatt gccgactagg ggacaagtaa aatctgaaaa acttacctga gctagagttt
    24181 cagctagttt ctggctagca ggctcaagga gagcggtgtg aaatggacct gacaccttaa
    24241 gaggaatcaa gcgtttggca cctgcttctt gcaaaagttc aaccgctcga tcaactgcaa
    24301 ccacttctcc agcaatgacg atttgtgcag gtgtgttata gttggctgga gtaaccactc
    24361 caagttcaga agctttttga caggcttctt caatgacctc tactggcgta ttgagaactg
    24421 ctaccatctt gccagagtca gcaggagccg cttcttccat ataggctcca cgcttagcta
    24481 ccaaggcaac cgcatcttca aaatccaagg cgccgcttgc caccaaggca gagtattctc
    24541 caagagacaa accagcaacc atatcaggct gatagccctt ttcttgcaat aaacggtaga
    24601 tagcaaccga agtcgctaga atggctggtt gcgtatagcg ggtctgattg agtttgtcct
    24661 cttccgtatc gatgagataa cgcaaatcat aacctagtac ctggctcgct cgatcaatcg
    24721 tttctttaac aatcggatac tgatcataga aatcccgtcc catccctaga tactgggcac
    24781 cttgaccagc aaataaaaag gctgttttag tcatttctta caactcctgt ccagcgagag
    24841 gcttcttctt gaattttctt agcggctccg taatacaaat cttttaggat ttcttcagct
    24901 gtttcttctt tagaaacaag ccctgcgatt tgacctgcca taacagagcc accatccaca
    24961 tcaccgtgaa caactgcttt ggctagagca cctgctccca tttgttcaaa gatttctaaa
    25021 tcaggatctt cttgcttaaa ggcatctttt tcagccagtt caaaatctct agtcaactga
    25081 tttttaatag cacgaacagc atgaccaaag tgctgagctg aaatcgtagt atcaatatcc
    25141 cttgctttta aaattttctc cttgtagttt ggatgggcat tcgactcttt tgcaactaca
    25201 aaccgtgtcc ccacctgtac agcctctgca cctagcataa agccagccgc agcaccttca
    25261 ccatccgcaa ttcctcctgc agcaataaca ggaatagata cagctgtggc tacctgtcgc
    25321 accaaggtca tggttgttaa tttaccgata tgccccccag cttccattcc ttctgcaata
    25381 acagcgtctg caccgatttt ttccatgcgt ttagctaaag cgacactagg aacaacagga
    25441 ataacgatta tcccagcttc atggaaacgt tccatatact tgcttggatt tcctgctcct
    25501 gttgtgacaa ctttaacacc ttcttcaata acgagatcca cgatgtcttc cacaaaggga
    25561 gataagagca tgatgttgac cccaaagggt ttatcagtca atgatttgat tttatcaata
    25621 ttggccttga caacttcttt cggggcattt cccccaccga taattcctaa tcctccagcc
    25681 ttggaaacag cccctgccaa atcaccatca gcaacccagg ccatccctcc ttggaaaata
    25741 ggatagtcaa tcttcaataa ttctgtaata cgcgttttca tagtgcctcc aaccttcctt
    25801 gcttacgtaa tagttcgatt tcaccataat ttgacagtca aactattacc taaacaagag
    25861 ggagtgggtt tctccctact ccttctacta atattctgct tattttgctt gctcttcaac
    25921 gtaagcaacc aagtcaccaa ctgttttcaa gtcattttct gcttcgattt ggatatcaaa
    25981 agcatcttcg atttctgaga ttacttggaa caagtccaat gaatctgcgt ccaaatcatc
    26041 aaaagttgat tcaagtgtta cttctgatgc gtcttttcca agttcttcaa cgataatttc
    26101 ttgtactttt tcaaatactg ccatgatagg actcctttaa aataaatagt ttttttataa
    26161 caatgtgttc accacatgat tacctaaatt gtaagaatga gcgtgcccca ggtcaagcct
    26221 ccaccgaagc ctgatagaag aacagtctgg ctaccatcta aagggatgag accttgttct
    26281 acacactctg aaagtaaaat cgggatactg gctgcactgg tattgccata ttccatcata
    26341 ttggctggaa gtttggctcg gtcaacacca atttttctag ccatcttatc caaaatacgg
    26401 tcattggctt gatgaagtag cagataatcc aagtctgtca cctctatagg agattcatca
    26461 atagtctgct tgatagactt ggctacatct cgaatggcaa aatcaaagac tgtgcgtcca
    26521 tccatcttca aaaacgaatc tgcactttct tgatctgaaa atggagaatg caaacctgaa
    26581 tgcccataag ttaaacactc gctgcgactt ccatcgctat tgagactctc agctaagaaa
    26641 tgctcttgct cgctagcttc taacaagaca ccaccagcac catctccaaa caacacagct
    26701 gttgatcgat ccgaccaatc gactgcctta gagagggttt cactaccaat caccaagcct
    26761 ttttgaaagc gaccagaagc gataaacttt tcagcagttg aaagagcaaa tacaaatcca
    26821 ctgcaagccg cggttaagtc aaaagcaaag gctttattag caccaatatt agcttgaaca
    26881 cgagcagctg tagagggcat catcgaatct ggagtaatgg tagctaggat gataaaatcc
    26941 agttcttctc ctgttattcc agcttttgcc atcagtttct tagcaacctc tgtagccaaa
    27001 tcactggtag attctgttct tgaaatatgc ctttgtcgta ttcccgttcg acttgaaatc
    27061 cactcatcat tggtatccat aatctgagcc aagtcgtgat ttgtaaccac ttgctctggc
    27121 acataatgag caacctgact tatttttgca aaagccatta tttcaaatcc tccaaaaatt
    27181 ggtaaagatt agtcaaacct ttacccatga cagcaatttc ttcctcgctc atgccatcaa
    27241 taattttttc taccatggcc ttgtggaagc gtttatgcag tctatgaatc aagcgaccct
    27301 tctttgtcaa atgcagatgc accacacgac gatcctgttc tgaccgaact cgctcaatgt
    27361 agcccttacg ctctaaattg ttcaaacttg tcgtaacagt tccaagagtt accatcaact
    27421 cttttgacac ttgacttgga gtcacatctg gagccttacc gatgacatca atcgtatgca
    27481 tttctttgat ggagatatcc ttaaaacgac tacctctcaa gttcacttcc tcaattacaa
    27541 ggacattgtt aaatatagat gttaaatatt cattgattcg ttggtagtcc atttttcata
    27601 tccctccttc ttcaaaaaac ttttacaatc aaaacatttg acagaaagaa ttatatcaaa
    27661 attcaaagaa tgatgcaagt attttttatt ttcctgtaaa tttaggtctt cttctctccg
    27721 aatgagctcg cactccttct ttgaaatcct ctgtttgagc taaggatttc tgtaggttca
    27781 gttctaaagt agcgtaaccc tgccagtctt taaattggct ctcccaaacc aacttcttaa
    27841 tggcagcata ggaattactt gaagcacgtc ttaatttttt aagaagctgt tctctcgtct
    27901 tttcaagttt ttcagcttca gaaacgcggt aaaccaaccc ccattctagg gctttttctg
    27961 ccgttaaagc ctctcctgtc atagctaatt gagcagcacg cgtcacaccg atactgcggc
    28021 tcaagagatg aattccccct gcatctggag ccaaaccaac accaacaaag gcttggataa
    28081 acttagcctt atccgtcgcc aaacagaaat ctgccgcaac agccatattc gctgcggcac
    28141 ctgcaacagc accgtcaact tccattaaaa caggtttggc tatttgcttg attttataag
    28201 aaatcgtatt gaccaactct gcgatttttg tcaatgatgg aatatcatcc tcatccactg
    28261 cccgcttcat ctctaccaaa tctcccccaa ctgagaagac ctttccattg gcattgatta
    28321 agataaaatg cacagctgga ttttcttctg ccaaagtcag agcttctaaa atctcctcac
    28381 acatgggaat atgaaaacca tttgcgacct caggacggtt caaggtaagg attgccaagt
    28441 cctcttcaag ctgataaata atgtgttcca tcagggctcc tttttatttt ataagcagtt
    28501 tatactcttc gaaaatctct tcaaaccgcg tcagcttcca tctgcaacct caaaacagta
    28561 ttttgagctg acttcgtcag tcttatttac aacctcaaag cagtgctttg agcagtctgc
    28621 ggctagcttc ctagtttgct ctttgatttc attgagtgtt aaattatttc actgtcaaag
    28681 tatatctttt ttaggagcag aaagcaagaa aaaatcgact gaaagtgtct cagccgataa
    28741 gaaaggctcg ctttaggcta gaaagcatct tattttcttc attgaaaaaa gcctttcttt
    28801 ctgctataat cgtataaaat acttacttta ggagttctta tgaaagttgt taaatttgga
    28861 ggtagttctc ttgcctctgc tagtcaatta gaaaaagttt taaacatcgt caaaagcgat
    28921 tcagagcgtc gttttgtagt cgtttctgcg cctggtaaac gcaatgctga agatactaag
    28981 gttacggatg ccctgattaa atactaccgc gactatgttg cgggtaacga tattagcaag
    29041 agccaaagct ggattatcga ccgctatgct gctatggtta gtgaattggg actaaaacca
    29101 gctgtgctag aaaaaatttc taaaagcatt cacgccttgg ccactcttcc tattgaagaa
    29161 aatgaatttc tctacgatac tttcctagca gccggtgaaa ataacaatgc caaattgatt
    29221 gctgcctact ttaaccaaaa tggtatcgat gcacgctata tgcaccctag agaagctggg
    29281 attgtggtca caagtgaacc tggtcacgct cgcatcattc catcaagtta tgacaagatt
    29341 gaagaattga caaacaccaa tgaagtcctt gtcattcctg gtttctttgg tgtcactaag
    29401 gaaaatcaaa tctgtacttt ctcacgtgga ggttctgata ttacaggttc tatcattgct
    29461 gctggtgtca aagctgacct ctatgaaaac tttacggacg ttgatggtat ctttgcagcc
    29521 caccctggta ttatccacca accacactcg attcctgagt tgacctaccg tgaaatgcgc
    29581 gagttggcct atgcaggctt ctcagtcctt catgacgagg ctcttcttcc tgcctaccgt
    29641 ggaaaaattc ctctggttat caagaatacc aacaaccctg accatccagg tactcgtatc
    29701 gttctaaaac acagtaatga tgaatttcca gttgtgggaa ttgctgctga ctcaggcttt
    29761 gtcagcatta acatgtcgaa atacctcatg aaccgtgagg ttggatttgg ccgcaaggtt
    29821 ctgcaaatcc tggaagaact taacatcggt tgggaacata tgccaacagg tatcgacgat
    29881 ctttctatca ttctccgttc tcgcgaacta actcccatca aggaagaaga aatcctgcgt
    29941 cagttggttc aaaagactaa agtagatcat gcagaaatcg aacacgacct ttctatcatt
    30001 atgattgttg gtgaaaaaat gaagagccac atcggagtga ctgctactgc gacacgcgct
    30061 ctatctgaaa acaaaatcaa catccagatg atgtctcaag gttctagtga agtttctatt
    30121 atgtttgttg tcaataaaga ccaagagaaa gcagcaatta aagccctcta caatgccttt
    30181 tttggagaaa gtaaggaaga ctaagcatgg cccaatcact taacaaaaca gtactcctca
    30241 gtacgacagg cacttcctac ctctctatcg ctgggaaagt tgggaaattc cttgtcggag
    30301 atcaggcttt ggaattttac ccagatgtca atgtcgaaca atttatccag attccttgga
    30361 gccatatcaa tcagattgga gccaatgtca ctggacgcaa aatcagccgc cacttcgaag
    30421 tctttacaga caaaggaaaa ttcctctttg cttcaaaaga ctcaggtgcc attctcaaaa
    30481 ttgcacgcga aaaactaggc aatgacaagg tcgtcaaact tccgaccctg attcagacaa
    30541 ttagccaaaa atttaaaaat ctatttgcaa aaaagtagaa actttagtat aatcatagca
    30601 acggataagt aggttatctt cttctttcag aaagtctgcg ggtgctgcga gcagatagga
    30661 gggataggtg aaattctacc gttagtaaca attacataca caatcaagtg cacacctgtg
    30721 aagttggatg gaaccgtggc cctgccactc caacgttttg tcaggcgtgc ttttttcata
    30781 aaggagttct tatgttagat atcaaacgta ttcgtacaga ttttgaagct gtcgcagaaa
    30841 aattagctac acgtggtgta gatgctgctg tcttgaatga aatgaaagaa atcgatgcta
    30901 aacgtcgtaa catcttggtc aaggttgaaa ctctcaaagc agaacgtaac acagtttctg
    30961 ctgagattgc ccaagctaag cgcaacaagg aaaatacaga tgacaagatt gctgccatgc
    31021 aaaatctatc tgctgaggtt aaagccttgg atgctgaatt ggcagaaatc gatgctaaat
    31081 tgacagaatt tacaacgact cttccaaata tcccagctga cagcgttcct gttggggctg
    31141 acgaagacga caatgtggaa gttcgccgtt ggggtactcc acgcgagttt gacttcgaac
    31201 ctaaagctca ctgggatctc ggtgaagacc ttggtatcct tgactgggaa cgcggtggta
    31261 aggtaacagg cgctcgcttc ctcttctata aaggcctcgg tgctcgtttg gaacgtgcta
    31321 tctacaactt tatgttggat gaacatggaa aagaaggcta tactgaagtc atcacacctt
    31381 acatagtcaa ccatgattct atgtttggta ctggtcagta tccaaaattt aaggaagata
    31441 cttttgaact cagcgatacc aactttgtct tgattccaac tgctgaagtt cctctgacaa
    31501 actactaccg tgatgaaatc ttagacggca aagatcttcc aatctacttc actgctatga
    31561 gtccgtcatt ccgttctgag gctggttctg ccggtcgtga tacgcgtggc ttgatccgtt
    31621 tgcaccaatt ccacaaggtt gaaatggtca aatttgccaa accagaagaa tcttacgaag
    31681 aattggaaaa aatgacagcc aacgctgaaa acattcttca aaaactcaac cttccatacc
    31741 gtgtcgttgc tctctctact ggagatatgg gcttctcagc tacgaagact tacgacttgg
    31801 aagtgtggat tccagcacaa aacaattacc gtgaaatctc aagctgttca aacacagaag
    31861 atttccaatc ccgtcgtgcc caaatccgtt accgtgatga agcagatggc aaggtgaaac
    31921 tccttcatac cttgaacggt tctggacttg cagttggacg tacagtggct gcaattcttg
    31981 aaaattacca aaatgaagat ggttctgtga ccatcccaga agcacttcgt ccatacatgg
    32041 gtggagctga agtcatcaaa ccataaaaaa taaggtttag ctatttctag ctagaccttt
    32101 tttcgtaacc aaatcagata agcacctagt acaaagaata aaatagttag gcatataatg
    32161 gtttcagcca ataccaggta atccagaaat ggaagtttca aaattccctg agccatcttg
    32221 agcgaggtcg ctgtgataat ggttgggaag gtgagggctg agaaggctgg ttgaaaacct
    32281 tgttttaaaa tgttgggcag acgagttaaa acaaagaaaa agaaggattg agaagccaaa
    32341 atcatgacaa tcaagaccca attcggcagg ctggttcctc ctactcgaac tagagaagcc
    32401 aagagtagag agaaaggagc acagtagatt ccttcttgtc caagcaaggc tagtgggagt
    32461 ggatgtttct ttaaatcgct ataaataagg ggatagagat agaaggtcaa gagaaaacca
    32521 aaactcaagg tcgcataggc aatttcgata atacctacca gaggataggt caaggcagcc
    32581 actgctatcc ccacatagag aaccgtccaa cttggagtgg catgaaccct ccgccctgga
    32641 caagcaaact tgatggtaaa accagcaatc aaggtcaaat ccaagagaaa tgaaaaccac
    32701 caaatccctt gtgctaccaa aggaagataa gagaatacgc gaaagacata ggtcgataaa
    32761 atcatcccag ccataggaaa ggttgccatt cctgacaaaa gagggggctt ggtcaattct
    32821 tgcttggttt ctttccaatt aaagagatgc agaattagaa agtaaatcca taaaaccaaa
    32881 ccagtcagac taaaaagatg ggatagaact ggcaacgtat ctaaaataag atttccagct
    32941 cctgccaaac ctagcaaaca acctgaaaat actaagggga gttttttcat cctaacctcc
    33001 aataatcatg ttagtttcag tataacataa aagcgcttaa atgaggattt aaaaaaacga
    33061 agtccgatta tttcagactt cattttactc agatatgaat taggcataag gttgcaattc
    33121 tggattaatt ggtgtattag ctaagttgtt ggcatagtta cagaggattg ctaggctgac
    33181 accaaaaacc acatccaagg cattttgttg agtgtagcca gcttctaaaa actcagacaa
    33241 ggcttcatct cctacacgac ccttggtatt gataactgcc aaggtaaact tagctagggt
    33301 atccaattta ggatctgttt caattggagt acgattgcga agagcttgaa tcaagtcatc
    33361 attcatctgg atttgtttga tggaaaaggc tgtgtgacct gcgacacaga aggcacaacc
    33421 attggtcacg gctgccgtga tttgcaccac ttcacgctca acgggtgtca ggctgttgcg
    33481 acggtggata gatgagacaa tttggtaggc ttctaaaaca gtcggggcat tggccaagag
    33541 accgattagg ttgggaatat agccattgtt gtctttttct actgtttcaa gaatttcttt
    33601 cacttctgct ggtgctgact ctactgtatg gatagtaaat gttgtcataa gatacctctt
    33661 ttcttattat tgacactaat attattggaa aatcttataa aatcctgatt cctaagttta
    33721 tctaagataa agctttattc tctcataaga ttttcgttgt tatattagtt tatcacactt
    33781 ccaatcactt gcataatata tattatatat caggctgata aaaattattt ataggcaaaa
    33841 aaatcacacg agctgtgtga ttccattatt tgtcaaaata ctttttagtt tcagcaataa
    33901 cgactggcga caagaccaag agggcaatca agtttggcag agccatcaag gcgttaacga
    33961 tatctgcgat aatccagacc atatccaact cgataaatcc tcctaacaag accatgagca
    34021 caaaaaccac acggtagagc cagataaagc gaaccccaaa gaggaactca aaacagcgtt
    34081 ctccgtaata gttccaacct agaatcgttg taaaggcaaa aagtacaagg aagatggtca
    34141 agagagcagg cccaaagtgt gaaaagactg ttgagaaagc tgactgagtc aaggcaaccc
    34201 cattcaagtc accgctccaa actccagtta ccaagatggt caaaccagtt agagtacaaa
    34261 tgatgagggt atcaataaag gttcctgtca tggaaatcaa accttgctct actggttcat
    34321 ttgtcttggc agctgcagct gcaataggag cagaacccag accagattcg tttgagaaca
    34381 caccacgcgc cacaccattt tgaatagcca tccgaacgct agcaccagca aatccaccta
    34441 ccgcagcaag gggactaaaa gctgaggtaa agactaaagc gattgtgcca gggatttttc
    34501 cgatattaaa gaaaataact gtaagagttc ctaagatata aatgagggcc ataaaaggaa
    34561 caacagtagt tgaaacctta gaaatagact tgagtccacc aaagactgca atcgctacaa
    34621 agacagacaa gacgagagct gtgatggctg gcgaaatcgt cgttgtattt tggatagatt
    34681 ctgtaatcga gttgacttgg gtgaaggttc cgattcccaa gagagcaacc aatactcctg
    34741 ctactgcaaa caaaacagca agtggtcgcc acttttctcc catccctaga aggatatagt
    34801 gcatgggacc tcccgctact gcaccatggt cgtccttggt gcggtatttg atggccaaga
    34861 gtccttccgc atacttggta gccattccaa agaaagccgc catccacatc caaaatagag
    34921 ctcctggtcc accaaccttg atcgccgtcg caactcctat gatatttcct gttccaacag
    34981 ttgatgccaa ggctgtacac agagctgcaa aactggatac atcaccatgt cccttatcct
    35041 ggataaaaat aagctgaaag gccttgggca gacgcaaaac ctgcaagagt cctagccgca
    35101 tggttaggta aacccctgtt ccgaccaata aaatcaagag gggcggtccc caagtaaaag
    35161 catcgattga tttaagcaat tctaacattt ccttctccta tcgtttcaac cccaaaagaa
    35221 agagcacatg caagatacat gtactctgga atgcttagat aaatgctaaa aagcggtcta
    35281 tcctagctct gtccttttac ctgagagttt gagcagttgc ctgccttgcc ccttcggtgc
    35341 ctttacggtc tctccagagt tccgtccatt tacagtcatg gaaaatcaaa cgattcccca
    35401 cttctattaa acttcattcg gtgttggtat taattgattc taattttaca aaaaatgttg
    35461 gcttttgtca atgtgtttat tagtaaaaat tagttcaaca gtttttactt tataaagtcc
    35521 agaatactgc tatcctttaa aagtgacaat agtcgcacca ctgcctccag cattttgtgg
    35581 ggcatagccg aaactcttga catgtttgtt tctttgcaag tatttggtaa ctccttcacg
    35641 gatgactcct gttccgatac catggatgat atcaacttga gccatattgt taagcaaggc
    35701 ttggtcgatg aaggtatcta gctcattcat ggcttcttca tagcgcttgc ctcgaagatc
    35761 cagtctagct tgaggtcctc gcccagaagt tcgtttcaca acattgacct gtttcttctt
    35821 gactgctttt tcttgctggg cttgaacaag atcaaactct ttctcttcca aggtcatctt
    35881 aatcaagcca acttgggctt cccagcggcc gtccttgagt tgactggtca aggtaccacg
    35941 ctgaccataa ctgagaacca cgatatcatc tcccaccttt ggagctcgtt ttttcttggc
    36001 cttttgaagg accttgtttt tagacaagtc cactttttca ggagccaatt ttttcaactt
    36061 ggccttggct tcaatgattt cgtggggctt gagttgggat ttactgtgga gatttttgag
    36121 aatctggtca ctttcactta gggccatatc cacaatctca gcagcctgtt cacgcgcctt
    36181 gttaagctcg gtttcctttt cacgattaag ctcgttgtag agttttttta gcgcacggtt
    36241 catcttgaga ttttcttgct ccacctcacg gatattgtcc aagcgtttgc ggctttccag
    36301 cgtctgctct tctaattgct caatgatacg attgacgtca ttgtcctgat cgatctgctg
    36361 actggcatct cctacgataa cttcagatag gcctagacgt ttggcaattt caaaggcatt
    36421 acttcggcca ggaacaccct gcataaagcg ataggtcggg cgaagagttg cagtatcaaa
    36481 ctccatactg gcattttgca caaaggctgt ctcaataccg taggccttga gttctggata
    36541 gtgggtcgtc gccatggtct tgatttgacg caggcgaagg tcctccagaa tagccatggc
    36601 aagggctgct ccctcttggg gatcagtacc agcccccaac tcatccaaaa gtaagagtga
    36661 atgttggttg accttaccaa gaatatccac gatattggtc atatggctag agaaggtaga
    36721 caagctctgc tcaatagact gctcatctcc aatatcagca aagatttctt caaaaatacc
    36781 aacacgactt cccttgtctg ctaaaatcgg caatcctgac tgggccatga cctgtgtcaa
    36841 gcccagagtt ttgagcatga tggtcttccc acctgtattg ggacctgtaa tgacaatagc
    36901 tgttaaatct tgaccaaaat agacatcatt tgcgacggca tttttgacca aaggatggca
    36961 gacatggagc agttgaatct cttgattttc tgacagctga ggcacgactg cttgtctttc
    37021 ttggataaat cgaaccttgg cacgaatcaa gtccagatga ccgataatcc aagcgtcatt
    37081 agcaatctca gccgcatgag ggcggacacg ctcagaaatt tcttggagaa tgcgaagcat
    37141 ttcatagcgc tcatctgctc gcagactagc aatttcttcg ctcagtttga ctacctcacg
    37201 tggttcgata tagacggtgt ttccactagc agaaatatca tgaacgacac ctgcaatctt
    37261 attgcggtag gtgtttttga ctggtaaaac ctgacggcca tttctgctag caacaattcc
    37321 ttctgtcaac atctgcgctt tttgcttgag caagtcttgt aaaacatcgc gtacctgact
    37381 ctcgctatca tgtatttttc gacggattcg cgccaattct tcactggcaa aattttcaat
    37441 gaaacccgca tcattaaagg cctgaagatt tccttgtaat tgcggaaaat catgtaattt
    37501 ctcaaaccaa agggctaatt cttccaagct gacattttcc agattggcgt aaaaactttg
    37561 aagttctcgg ctggcaagaa gcacgcgttt caagagtagg aactcctcga tattgagatc
    37621 cgctcccatc tccaacctct tgcagactcc tgcaatttcc ttagttgaga gaatagtaaa
    37681 atgcggttgc tcgacgaaaa gagcctgcat ttccttcatc tcagcaaaag cctgtttgat
    37741 tttatctgct ttggcagtcg gagccagttg tctcaattgc tccaagccct gctcggtcaa
    37801 caaatgaggc tcaaacaagg ccttgacctt atcgaactct aatgtttcta atattttctt
    37861 attcatcttt atttccttgt ctttgaatgt ctaggtgtgg tagcttttta cattctgata
    37921 gattcgagtc aaatctgtaa acaaagggct aggaaaactc ctgccctttt tatccgatta
    37981 aatttgtcac ccagatttgt ttgagccaac tggttgttat cggtatgctc tggatgatgt
    38041 gttttgcgac gatactcttt tcaagaggat tttgtataac tgccatgggg atggtcgcca
    38101 agattgtcaa ggccatttgc aagacaaata aggtcaccaa catggacaag atacctgctg
    38161 aaacttggaa caacttacca cccagttttt tgctaggaat caagtgtaag agaagaccaa
    38221 gcaaacgacc aatgctatag acaatcccaa atacaagcaa gtagccgatg cctgcataaa
    38281 agaccttatc cagctgaaag agttgatccg atgggaaaaa gaaagtcccc tgaccttcct
    38341 gcgaatttgc ataagggagc aataaatgga attgctctcc aagcccctta taaaactggc
    38401 cagccataaa agccgatgcc atggctgaaa tcaggtaata aacctgtaag agcaggcctc
    38461 tccgatagcc gatataaaat ccccaaacca agaccaatag aagaaggaat gaaatcataa
    38521 ggaatcctca atcttgctct gttcttgctt acaagtcaca agcttgtgac ggagttcttc
    38581 tagctcttgc tccttatcgt caaattcaat ctcacggctg agctgagttg ataaacagtt
    38641 gactgccaac aaaagagcga ttgtttcatc atctgcgcta ggcatttgtt ctttaattgc
    38701 ttggtatttt tctgtcgcaa ccttagcgat ttcctccata aaaaggttat catgttcgct
    38761 tgtcaaggtt aacgattttt tcccgaatgt aaatttgaat cgatttagat ttgccataaa
    38821 attcacctca cgatattata ccaaaattcg ctaattttgt cagtttttac aaattttact
    38881 gcttttgtgg tacaatagaa actatggcaa gtatcacact cacaccaagc gaaaaggata
    38941 ttcaggcttt tcttgaacac tatcaaacca gtctggctcc tagcaagaat ccctatatcc
    39001 gctacttttt gaaactacct caagcaacgg tttctatcta tacttctgga aaaatcttgc
    39061 ttcagggtga aggggctgaa aaatacgcca gtttctttgg ctatcaagct gtagagcaaa
    39121 ccagcggaca aaatcttcct ttaattggga cagatgaggt gggaaatggt tcctactttg
    39181 gtgggcttgc agttgtggct gcctttgtca cacctgacca gcacgacttt ttacgaaaac
    39241 tcggtgtggg ggattctaag actctgaccg accaaaagat ccgtcagatt gctcctattc
    39301 tcaaggaaaa aattcagcac caggcactcc ttctctcacc cagcaagtac aacgaggtca
    39361 tcggagaccg ctacaatgct gtttcggtta aggttgccct ccataatcag gctatctatc
    39421 tcctccttca aaaaggtgtt cagcctgaga aaattgtgat tgatgccttt accagtgcta
    39481 aaaattatga caagtacttg gcacaagagg ccaatcgttt cagcaatcct atcagcttag
    39541 aagaaaaggc tgagggcaaa tacttggctg tcgcagtttc ttctgtcatt gcgcgtgatc
    39601 tctttctgga aaatcttgaa aatctgggac gagaactggg ttatcagctc ccaagtggag
    39661 ctggaacagc ttctgacaag gtggctagcc agattttgca agcctatggt atgcagggac
    39721 tcagcttctg cgccaaattg cactttaaaa acactgaaaa agcgaaaaaa cgcttagaaa
    39781 ggtaagttat gaattcattt aaaaatttct taaaagagtg gggattgttc ctcctaattc
    39841 tgtcattact agctttaagt cgtatctttt tttggagcaa tgttcgcgta gaaggacatt
    39901 ccatggatcc gaccctagcg gatggcgaaa ttctcttcgt tgtaaaacac cttcctattg
    39961 accgttttga tatcgtggtg gcccatgagg aagatggcaa taaggacatc gtcaagcgcg
    40021 tgattggaat gcctggcgac accattcgtt acgaaaatga taaactctac atcaatgaca
    40081 aagaaacgga cgagccttat ctagcagact atatcaaacg cttcaaggat gacaaactcc
    40141 aaagcactta ctcaggcaag ggctttgaag gaaataaagg aactttcttt agaagtatcg
    40201 ctcaaaaagc ccaagccttc acagttgatg tcaactacaa caccaacttt agctttactg
    40261 ttccagaagg agaatacctt ctcctcggag atgaccgctt ggtttcgagc gacagccgcc
    40321 acgtaggtac cttcaaagca aaagatatca caggggaagc taaattccgc ttctggccaa
    40381 tcacccgtat cggaacattt taagaaacct aagaggccga gaatcaccaa tctcagcctc
    40441 ttcttctatc gtgagaagtg attgtttatt gacaaatact caatgaaaat caaagaacaa
    40501 actaggaagc tagccgtagg ctgcttaaaa cagtgttttg aggttgcaga tggaagctga
    40561 cgtggtttga agatattttc gaagagtata aaataaaaac aatcccaact ctcacctatt
    40621 catgcaaagg aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga
    40681 aaatcccagc aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga
    40741 ttttgatgac tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga
    40801 ctatactttt tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag
    40861 tcgttatgat cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca
    40921 tttcaagggg attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac
    40981 cattgacgaa attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa
    41041 aaatcgcgag gctttcgtct ccactctccg tctcaactac ggtacggaga tggttttggc
    41101 caaactagcc aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa
    41161 ggaagaaacc cttgatgtgg ttgaaaatta tccctaccaa ctggttgagg atatcaaggg
    41221 tttgggcttt accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc
    41281 tgaacgcttc cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacaggaga
    41341 cacctatgtt gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg
    41401 tcccgtggaa ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga
    41461 caaggttcag cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg
    41521 catccgcagt cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaaa
    41581 aaccattcaa aaacatatca ctactatcga gaaagagctt ggaattgagt atgataacat
    41641 tcaaaaacag gctatctgtg atgctatcca gaataaggtc tttatcctga caggtggacc
    41701 tggtactggt aagacaactg ttatcaatgg gatcatcgct gtttacgccc tgttagaggg
    41761 acttgacctc aggaagaaaa gcaacctgcc cattcttctt gctgctccaa ctggtcgagc
    41821 tgctcgtcgc atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg
    41881 aatgacaggt gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat
    41941 cgtggatgaa ttctctatgg tggatacttg gctggccaat caactcttct ccaatatctc
    42001 ttctaacagt aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg
    42061 acaggttcta gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat
    42121 ttatcgacaa agcgaagaat caaccatcgt caccctagct agtcagattc gacagggcat
    42181 cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg
    42241 ccatattcct gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg gtattcctgc
    42301 ccgtgatatc caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa
    42361 tcagctcatg caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc
    42421 tcagtgccac tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa
    42481 tgtctttaat ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc
    42541 gaaacaagac gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga
    42601 atggtacaag attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt
    42661 cccagttgtc atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat
    42721 ctacacagcc attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt
    42781 cgactatgct acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag
    42841 tgatctactg gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag
    42901 tgcctctgaa caatcctaca tcctaaccga agaaaactgg gacagcattc cagccatgat
    42961 tgggattaca gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaaaccac
    43021 caattcaggt gggttttctg tttattaaga ttattttact gttgctgtgc ttgtaatcaa
    43081 ttcaacagct tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg
    43141 aacttgtgca acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc
    43201 ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt
    43261 agtacgtgac tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt
    43321 gatttggaag tacatgtcag ggttgatccc ttgacgttgc aagttcccaa ggaattcatt
    43381 tactgaacgg tgaacttctt cgtggatcat ttcttctgga agttctacga tttcagcgtt
    43441 ttctacagct gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc
    43501 agtagccaat tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc
    43561 aatgtctttt gcaagttcat cgtcaagagc cggaacttct ttagctttta cttcgtggat
    43621 agttgtcacg aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa
    43681 tgttacgata acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc
    43741 agggatgaat tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa
    43801 ttcaacaccg tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc
    43861 agcttccttg ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcgac
    43921 atcagcgtca gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc
    43981 caattttact tcaggttttg taacgacttc agcagtgata acccagtctt gacctttttc
    44041 cattgaagtt acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc
    44101 tgcttcataa gcgtttggca aaagtgcgtt cattgcatct tgataaagag cttcttcacc
    44161 aaatttttgg tcgaagatag ggcgtggaag gtgaccttta cggaaacctg gaacattaag
    44221 agatttcttc actgacttga agacacggtc caattctggt ttgatttggt cttgagagat
    44281 agtgaaagtc aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc
    44341 atttctcctt aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta
    44401 gactaatgca gacaattata gacaacaagc ctttttccta actaaaacac tcataaagta
    44461 tagacaattt tagactactt tggatatctt ttggttagtc actttccaaa actaatttat
    44521 ctaatttttc agttatattt gacttcatct tctcagtaac atgagtataa acacttaaaa
    44581 tctttgtttc attagtataa tctacacgat ccattatcgc tgttataggt acttccaatt
    44641 cagcaagcaa acttatatgc gaatatctaa aaacatgagc agtcaataca aaatcatctt
    44701 tcttaatttc acttttccta aaactgtttt tcaaaaagta attgaaacaa gttatcatta
    44761 agggagaacc attatttgta aatatataat caccttcttc taaaagaaga tattctttta
    44821 aaatttctaa cactctatca ataataccaa ttactctata tgaagctaaa cttttcggac
    44881 tatccaaaaa cacttcgtta ttggacgatt acattatagt aaaacgaaat aagaacagga
    44941 caaatcgatc aggacagtca aatcaatttc taacaatgtt ttagaagtag aggtgtacta
    45001 ttatagtttc aatctactat acaagacgaa attgaagaaa tctttccatt ataaaacgca
    45061 tattatcaag gtttttaaac acctaataat atgcgttttt tcctatttta aagactttta
    45121 tccacctatt atacaaagtt aagtatccat cacagtttac aattaacctt cattacctaa
    45181 cccattcacc atccttcaag agagtaacct ttaagaaccg aataaataaa taaatgacaa
    45241 atttcgttca tttaatttaa ctgcactgtt aatttgatta gctccatctc ctaaagtatg
    45301 cactcctact acgcggtgac tagcatcata aactgcagat ccactagacc tctctaaagt
    45361 atcaacttgg taatccaaga acatgccatc atcacttaaa acttgttttt tatctgtata
    45421 catttgataa attttaaaat tatatgatgg atagcctgtg atagtcacag ttattcctgt
    45481 caaatttttt tgactagtag gaagacccaa agtccctaat tttgcaccaa tgggctcttc
    45541 tagaattaat aaagccaagt catattccct tgcattctta gaatttaaat ttctaaattc
    45601 cttcaaataa cgaacttcct ttactttgat ctttccaaat agttcttgac ttggactaac
    45661 agccggaaga acataaatat catccgcttc tttcccatag tcatgtctgt aatagttgtg
    45721 agccgctgta attaacacat tatctttaat aaaattcgca cttcccctcc cttctacatt
    45781 cattccatcg gctactccat aatacttaga taaaaccata gctgaagtcg aatacggata
    45841 ctgtaaagta ttatcaattt taatcaaatc atcattaccg ataatacttc tgattgcttt
    45901 tgatagtatg aaccatacgt tggtgaaatc tcagataatg aagaatcatt agaccctgga
    45961 cctttttcta gtgtctcact tacctcatat tcttcacctg tactagaaat aacactcaaa
    46021 gcagatactg tcgataactg gctagccaat aaagtactcg caataattga aatacccaat
    46081 tttttataaa cagttttctt cattatcgta tcctcctaat gtaattatag tgtactattc
    46141 taaatttctc aatctactat agaatcaaga aatctaccac cttctttaaa taccctccat
    46201 tatcacataa acaggtaaac ttttcaatta atgactgcgc ttttcaatca cgctagaggt
    46261 acttgcttgc ttctttgata ctaagttcag ccattctttc cttgtttttc tcaataaagc
    46321 atgttaccca agtgggattc gttttggagt agtctcgcag agtccagcca atggctttat
    46381 tgataaaaaa ttctgtttgg ttcaagttat gaaggagaat cttttccatt aattgagtat
    46441 tggtcttctc ttttcttaac aactggtggt caatagcgac acgtctcagc caaatattat
    46501 ctaataggct ccattttata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca
    46561 gattgctcaa aacactgttt tgaggttgca gatagagctg acgtggtttg aagagatttt
    46621 cgaagagtat taagattatt tcttctagtt cagggtgttc atacaccaaa ctccctacta
    46681 ctcgatctag gatatctacc gtgtcccacc aggattttgt cacgactaac tgctctagct
    46741 taggcaaatc ggtttccttt agataagact gcattgcttt caaatagtta gcagccacat
    46801 attggtattt tctaggctcc ttttcccagc aagtgtctgc aaaatcccaa tcgataatct
    46861 ttgttttttt cgcttctgga aaatattttt atagagttta tttctttcag gcaccgcaat
    46921 acctagaaaa gaaaattgat ggcgcatata ggcttccatg gaccttgctt ttttagagtc
    46981 ttttgctgct tctagctcct caagtaaatc tgctaaactc atctaaaact cctcttgccc
    47041 caccaaatgg tgctgaaagg catagacagc cgcctgggta cgatcgctga cttcaagttt
    47101 ggcaagaata ttggacacgt gggtcttgac cgtcttgaga gagataaaga ggtcatctgc
    47161 gatgcgctga ttttcgtagc ccttggcgat gagttggaga acatctcgct cacgcgcagt
    47221 caattcttca tgaagttcca tatgattgcg gtggtattca accttcttgc taacctcttg
    47281 ctcaatggcc agctcgccag cagctacctt actgacggca tgaagcaatt catctgcact
    47341 agaagtcttg agcatatagc ctttggcacc agcatctaag actggcatga ttttttcatt
    47401 gtccaaataa gaggtcacaa tcaaaatctt ggcttcaggc cattctttaa ggattgctaa
    47461 ggtcgcgtca attccattca tctcaggcat gacaatatcc atgacaatga catctggacg
    47521 cagttccaag gccaagtcaa tcccttgaga cccgttggac gcctcaccca caacttctac
    47581 atcgtcttgg aggtcaaagt agcttttcaa acccaaacgg accatttcat ggtcatctac
    47641 tagtaaaatt ttcatcttta ctcctttatc attccttatc taacagggga atacggatat
    47701 caactgccag cccttgcttg ggagctgtta ataactgaac cgttcctgcc atatcttcaa
    47761 cccgctcctt gatatttcgc agtccataac tcaagtcgtc taagctccct aactggaaac
    47821 caatcccatt gtccaccacc ttcagttgca attcaacatc tgtctgatag aggtagacat
    47881 ctaggcaaga tgcctgggca tggcggaggg tattgctaat caactcttgc aggatacgga
    47941 agatatgctc ctcgattttc ttaggcaatt tcgtcatatt ctgcttgaga ctaaccctaa
    48001 gatcactctt gtcctcaagc tcttttaaga gaatctgaat cccttctatc aagctcttct
    48061 gctccagttc aactggtcgc aaatgcaaga gcaaaacccg caaatccttc tgggcagttt
    48121 ctaaaatagc tgtgacactc tgcaactgga tctgcatctt ttctctatcc aatttcaaag
    48181 cctgctgact gatacccgat aaaatcatgt gggccgcaaa caactcctga ctgactgtat
    48241 cgtgcaaatc ccgagcaatt cgcttccgtt ccttctcgat gatttcctct tcctgagcaa
    48301 ggctctgatt ttcagctttt tgaagagcct ctgtcaaaag gttaagttta cctgataagg
    48361 acttgaaact ggcatccaaa tctggatctg caacctgaac cacttcttgc cctgctaata
    48421 aacgcttgag attagcctgc atttttctta gagaaagctc ttcgatccct cgccaaaaca
    48481 gggctaagag acaggtcatg gacatgctga aaaccaacaa taaaaagaca aatttttctg
    48541 ttttttcgac atcgtgcaaa aagatagacc agtcaaaatc aagtatttcc agcaagctgt
    48601 gggagaaaaa aaagacaaat aggaaggagg tgagagcaat aatgacatag gcttgttttt
    48661 tcatcctcta accacctcca catcaccaat catagtggtc aagaaaatct tgacactctt
    48721 gttactcttg agatagtctt ttgtttcttg atgatagtgt tcattgcgga gggctcgctt
    48781 gggctggttg aaaaaagtca aatccccata gagacagtta acgctgagac tgacttccac
    48841 atctacaggt acgatgattt tggtcgttcc taccatcttt ctgaggataa tgacattgtc
    48901 atgattggtt aagatgaccc tctccagatg aatagtgtcc ttgcccatga agcgaaagag
    48961 attgatatca tcgaattggc aagtctggta gtttgaaaaa tgatgaagat ttccaaacca
    49021 acgatttttc tccttcttaa ccgtcacgac ctcttcaaaa accaaattgg tctgctcttt
    49081 ttcctggttc atcatcgggt aaagaagaaa gaggctatag ataaccgcaa caaaaatagc
    49141 tagaatcaca aaaggattga gcataacgat gaaaaagaag agaatggtta ccgctactaa
    49201 aagaagatta tttccctctt taccagtgta gtagcgaatc aaaagcaaaa agaggaatag
    49261 tatcagcaga aaacgcgaaa aatgctctga taccatcaaa atcagagctc ctgtcagaag
    49321 acaggcttcg ataaataaaa agattttaaa ttttctcata ggttcatcct ctcccttcta
    49381 ttttatcaca attcaaaaaa gtcacctcag tctgaggatg gaaaaaaggc gctggttacg
    49441 cctttttcat ctgatccttt gcttctttta attttccata aagaagatag tctacttttt
    49501 gtagatctgc tatggtggca cagttaaggg aacacataat caagcgtagg tctgctttcc
    49561 agccttggac aatgccaatc acttcttcaa ctgtgtaggt ttcaaccaat tccagaacgg
    49621 ttcgtgacaa tcccacagcc ttagcaccaa aaaccaagca cttaatcata tccagcggat
    49681 tccgaacccc tccactaacc aagagttcga ccttatcttt ccattcttgg gcattgagaa
    49741 gggcctgcat ggtagactga ccccattgat tgaggtaatc acgctggcca ctacgacggt
    49801 tttcgatata ggcaaagctg gtgccaccac gacccgatag gtccactgta cgaacaccga
    49861 attcataggc tctttcgatt gtcttggcat ccattccaaa gcccacttcc ttgaggacaa
    49921 taggaacggg aatttgcttg ctataatctg ctagatgcga ttgccagctt ctaaacttcc
    49981 tttctccctc gggcatgagt aattcctgca tgacattgac atgcacttgc aatagaacag
    50041 gattcatctc ttctacagtc tgaagtccta actcgacagg cttgtccaat ccaatattgg
    50101 ttccaaggag gagattggga tgactagact tgacagaaaa agaatcatcc gttggatttt
    50161 tgagggctgc gctataagaa cccgttacaa ataaaatacc acaggattcc gccacctgag
    50221 ccagcttttg attgatttct cttcccttat tacttccacc agtcatggca ttgatataaa
    50281 aaggaaagtc ccactttcga ccagcaaact ctgtcgaaag attgatttca tccagattgt
    50341 aaagaggcaa ggaagaatga atcagctcca cctcatcaaa gctattatag gaacttttct
    50401 gctcaagggc atagaggata tgctcgtcct tacgatttgt cgtcatgtcc tatcctttct
    50461 tgatataaga gctcaatccc cagatcggcc caacgatttt ttaaggtttt ggttgattgc
    50521 gcatcaaaac tcagggcgat gccacagtca ccaccaccag caccactact cttggtaacg
    50581 gcctgcaaat cttgactggc ttctttcaac tgtctaagca aaggcgtgta aatatctgta
    50641 ctcaagcctt ctaaaagctt gctggctact tctacttgct cgataacttt ttcggctttc
    50701 ccctgctcca aggcttcgac caaaaaaacc accgtttctt ttgaggaagt taaaaaattt
    50761 tgattgatat tttgcttgat ttgctggacc atgtgactcg atacagccac ttccttggtc
    50821 catcccacta agaaatcaca ttctaaagtt ggtttcactt gtgagataaa aaagccccaa
    50881 tcacgctcta aaacagtcgc caagttttct tctttcaacc aagcagctat cttctggcga
    50941 tcaaatgact ggtagagaac caaatcctct gccacaatac aggcaaggtc gcccatggaa
    51001 ccattgtctc ctcgcttgag caagacagcg ctagtcagct tgaacaagag attctgatca
    51061 accgaaagat tatagagagc cagtaaagcc ttgacaacca agacaacgac gctgccacta
    51121 gaacctagac caaacttttt cccttctcgt tccattttgc cacagatttc tagggaaaaa
    51181 ggtcttaaat tctgaccgcg aacagcgaag aagtctccca tcaaagcaat cgtttcttga
    51241 atcaagctgt agtcaggatt gggccttaag tccactgcga aatcaaacat atctgaatag
    51301 atacggtagc tgtcagaaaa agcaatatca gccctcatat agatgggaat atcctttatc
    51361 aaagctaact gccctggctc taaaatagca tattcacctg ccaaatagag ttttccgcaa
    51421 gttttaacag caatcatctt gactcaaatc ctttgttttt gacacaatca agcgataacg
    51481 ctgaccgaaa atttctgata aatgctccaa gtctttctcc tgacagaaga ccttaacatt
    51541 gggaccagca tccatggtaa agtagcaggc ctctcctttc tcacgaagct ggcgaacaaa
    51601 gtccatagcc tcataagagg catccgtcag ataagaaaag gctggactag cagtctttgt
    51661 cgtagcatgc atagccaggg catttttctc cgttaattct ccaatcttgg caaaatcatt
    51721 ttccttgaga taaatcagca tatcctgata gtccttctca gactgacgaa cccagtcgtc
    51781 aaaagtcgtc gaggtttcca cacaaagttt catcccatca cggctagaga ttggtttttt
    51841 cttgtcctct agcaccaaca taatcatagc tagtttcaag tctgtctcta cagggtaaat
    51901 ttctccacta tccttatccc aggctcctag tggtccataa aaactccgag aagaagagcc
    51961 tgaggcaaac ttggcttcct gcgctaactg acttctatcc aatccaagct tgaaataagc
    52021 attacaagcc ttgaccaggg cggacaaacc actagaactt gaggacaggc ccgctgccgt
    52081 aggcatattg ttttgagtat cgatacggac aaagccctca ccagctggac gataacggtc
    52141 aataatctta ctcatcttgg catgctcgac ctcattttgt agctgaccat tgatgtaaaa
    52201 ttcgtcagct gttacattgg ctggtaaagg cgacaaggtc gtctctgtat acatattttc
    52261 caaagttaga gaaatactgc tggtagcagg caccatctct ttttcttttt tctttcccca
    52321 atatttgata atagcaatat ttgcgtagga acgtactgtt acaggctctc tatccatgtc
    52381 tgaacagctc ctttctcttc taatctttct gctagttctt gtgcgtgtgt caaattggtt
    52441 accaaggcta tgatacaacc tcctagccca ccaccgctca tcttggcacc cagagcacca
    52501 tggctaagag tcgtttcaac caaaaagtct gcctcagggc tactgactcc aatttctttt
    52561 aaatgtaaat gcgcttgact gaggatttgt cccagtcctt cagcatcttt ttgtgaaatc
    52621 gcaacttctg cttgctgggt taattctccc aaggcatgca aaaacggtag ggcatccttg
    52681 cccttatttt gaaccacttg gatggcttca cgagtatgac cataaacacc cgtatcggca
    52741 atcaccaaat aggcggataa atccatctca agttctgtaa atcctacgtt cttgataaag
    52801 cgaataggtt ggtcactgag acaggtctta gcatccaaac cactaggatt catatgggca
    52861 atcatttcag ctcgattgac caagatttct agtacatcat gaggcagatc agcctgatag
    52921 tagtcaaata ccgcacgaat ggccgctatg ctgatagccg ctgacgaacc catcccccgt
    52981 ttctcaggga tagccgagtc aatctcacaa cgaatgcagg cttctgtgat atccaaatac
    53041 tccagtgagg cataaaccgc catggacaag gtatcctcct cataaaggcg ccaaggactc
    53101 tctgcaggaa ctaccttaca ggtcacctcc acctccaaaa gaggcaggga aatggcagga
    53161 taaccgtaaa cgaccgcatg ttcccctatt aaaattatct tactatgtgc ctgaccgaca
    53221 ccaacttttt ttgtcatttt ttccttttac tagacgaaaa aacgtcttat ttttcataca
    53281 agtattaatt ctttcctatc tattttatta tattttcaca aaaaaagcga ttgtttccat
    53341 tcacaatcgc ttctttcatt attgaaccca ttcgccatta tagttgacag aatagccatc
    53401 tacggtcgta ttcactgcca aggcacctga gctataagcg tagtaccatc tgccattgac
    53461 ctggaaccaa cctgtcgtca tagaacgacg aaagaaactc cataccgtta agtaaagagg
    53521 aaagtcgtga gggatcatgc gccattgaca acctgtttta gtgacgtaca aagtctcatt
    53581 aacaagtact cgtttcggcc atttataggt gcggtgtttg gagaaatagg gttcaatctt
    53641 agcccattct tgatcgttta aatcagtatc atatgctttg cgtgtcataa ctctagttta
    53701 acattttttt gtgaatacag gttctaaata atcgaccacg aaaatttctt aagtggaaaa
    53761 cgccttatga agtatgctac gggaaagtta tgcacttaat ttgacaattc aagatgtaaa
    53821 aatatatact atagta
//
LOCUS       DBEJJE010000007        50902 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEJJE010000007 DBEJJE010000000
VERSION     DBEJJE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.07"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(536..1225)
                     /gene="rplA"
                     /locus_tag="ACL3F5_000430"
     CDS             complement(536..1225)
                     /gene="rplA"
                     /locus_tag="ACL3F5_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0514290.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVTLAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1433..1858)
                     /gene="rplK"
                     /locus_tag="ACL3F5_000431"
     CDS             complement(1433..1858)
                     /gene="rplK"
                     /locus_tag="ACL3F5_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0514291.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2167..2883)
                     /gene="ldcB"
                     /locus_tag="ACL3F5_000432"
     CDS             complement(2167..2883)
                     /gene="ldcB"
                     /locus_tag="ACL3F5_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0514292.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2886..3356)
                     /locus_tag="ACL3F5_000433"
     CDS             complement(2886..3356)
                     /locus_tag="ACL3F5_000433"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0514293.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3358..4395)
                     /locus_tag="ACL3F5_000434"
     CDS             complement(3358..4395)
                     /locus_tag="ACL3F5_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0514294.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            complement(4493..5818)
                     /gene="brnQ"
                     /locus_tag="ACL3F5_000435"
     CDS             complement(4493..5818)
                     /gene="brnQ"
                     /locus_tag="ACL3F5_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0514295.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5989..6276)
                     /locus_tag="ACL3F5_000436"
                     /pseudo
     CDS             complement(5989..6276)
                     /locus_tag="ACL3F5_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6436..6615)
                     /locus_tag="ACL3F5_000437"
                     /pseudo
     CDS             complement(6436..6615)
                     /locus_tag="ACL3F5_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
     gene            complement(6734..8134)
                     /gene="pepV"
                     /locus_tag="ACL3F5_000438"
     CDS             complement(6734..8134)
                     /gene="pepV"
                     /locus_tag="ACL3F5_000438"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0514296.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8147..8752)
                     /locus_tag="ACL3F5_000439"
     CDS             complement(8147..8752)
                     /locus_tag="ACL3F5_000439"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0514297.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            8923..9723
                     /locus_tag="ACL3F5_000440"
     CDS             8923..9723
                     /locus_tag="ACL3F5_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0514298.1"
                     /translation="MKKLSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9905..10738)
                     /locus_tag="ACL3F5_000441"
     CDS             complement(9905..10738)
                     /locus_tag="ACL3F5_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0514299.1"
                     /translation="MNHKIAILSDVHSNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINTGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10728..12572)
                     /gene="uvrC"
                     /locus_tag="ACL3F5_000442"
     CDS             complement(10728..12572)
                     /gene="uvrC"
                     /locus_tag="ACL3F5_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0514300.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(12611..13317)
                     /locus_tag="ACL3F5_000443"
                     /pseudo
     CDS             complement(12611..13317)
                     /locus_tag="ACL3F5_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
     gene            complement(13396..14628)
                     /gene="murN"
                     /locus_tag="ACL3F5_000444"
     CDS             complement(13396..14628)
                     /gene="murN"
                     /locus_tag="ACL3F5_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0514301.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14633..15853)
                     /gene="murM"
                     /locus_tag="ACL3F5_000445"
     CDS             complement(14633..15853)
                     /gene="murM"
                     /locus_tag="ACL3F5_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0514302.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15965..16744)
                     /locus_tag="ACL3F5_000446"
     CDS             complement(15965..16744)
                     /locus_tag="ACL3F5_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0514303.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16813..18474)
                     /locus_tag="ACL3F5_000447"
     CDS             complement(16813..18474)
                     /locus_tag="ACL3F5_000447"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0514304.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18649..20871)
                     /gene="recJ"
                     /locus_tag="ACL3F5_000448"
     CDS             complement(18649..20871)
                     /gene="recJ"
                     /locus_tag="ACL3F5_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0514305.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21148..21906
                     /locus_tag="ACL3F5_000449"
     CDS             21148..21906
                     /locus_tag="ACL3F5_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0514306.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            21917..22711
                     /locus_tag="ACL3F5_000450"
     CDS             21917..22711
                     /locus_tag="ACL3F5_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0514307.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQANTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRDPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQSSITQRLITE
                     LGKKKGLTFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22724..23401
                     /locus_tag="ACL3F5_000451"
     CDS             22724..23401
                     /locus_tag="ACL3F5_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0514308.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQSFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIVSGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23411..24070
                     /locus_tag="ACL3F5_000452"
     CDS             23411..24070
                     /locus_tag="ACL3F5_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0514309.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24328..25518
                     /locus_tag="ACL3F5_000453"
     CDS             24328..25518
                     /locus_tag="ACL3F5_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0514310.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKTSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25839..26720)
                     /locus_tag="ACL3F5_000454"
     CDS             complement(25839..26720)
                     /locus_tag="ACL3F5_000454"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0514311.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26861..28189)
                     /gene="vncS"
                     /locus_tag="ACL3F5_000455"
     CDS             complement(26861..28189)
                     /gene="vncS"
                     /locus_tag="ACL3F5_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0514312.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28186..28842)
                     /gene="vncR"
                     /locus_tag="ACL3F5_000456"
     CDS             complement(28186..28842)
                     /gene="vncR"
                     /locus_tag="ACL3F5_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0514313.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28891..28974)
                     /gene="pep27"
                     /locus_tag="ACL3F5_000457"
     CDS             complement(28891..28974)
                     /gene="pep27"
                     /locus_tag="ACL3F5_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR0514314.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29154..30533)
                     /gene="vex3"
                     /locus_tag="ACL3F5_000458"
     CDS             complement(29154..30533)
                     /gene="vex3"
                     /locus_tag="ACL3F5_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0514315.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30585..31232)
                     /gene="vex2"
                     /locus_tag="ACL3F5_000459"
     CDS             complement(30585..31232)
                     /gene="vex2"
                     /locus_tag="ACL3F5_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0514316.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31245..32522)
                     /locus_tag="ACL3F5_000460"
     CDS             complement(31245..32522)
                     /locus_tag="ACL3F5_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514317.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(32879..33049)
                     /locus_tag="ACL3F5_000461"
                     /pseudo
     CDS             complement(32879..33049)
                     /locus_tag="ACL3F5_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33192..33791)
                     /locus_tag="ACL3F5_000462"
     CDS             complement(33192..33791)
                     /locus_tag="ACL3F5_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514318.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(33928..34812)
                     /locus_tag="ACL3F5_000463"
     CDS             complement(33928..34812)
                     /locus_tag="ACL3F5_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0514319.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(34816..35202)
                     /locus_tag="ACL3F5_000464"
     CDS             complement(34816..35202)
                     /locus_tag="ACL3F5_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0514320.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35195..36538)
                     /gene="cysS"
                     /locus_tag="ACL3F5_000465"
     CDS             complement(35195..36538)
                     /gene="cysS"
                     /locus_tag="ACL3F5_000465"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0514321.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVAA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKDFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(36620..37504)
                     /locus_tag="ACL3F5_000466"
     CDS             complement(36620..37504)
                     /locus_tag="ACL3F5_000466"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514322.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSLY
                     QDQISQLKFQAFSEGHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(37516..38133)
                     /gene="cysE"
                     /locus_tag="ACL3F5_000467"
     CDS             complement(37516..38133)
                     /gene="cysE"
                     /locus_tag="ACL3F5_000467"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0514323.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(38149..40362)
                     /gene="pnp"
                     /locus_tag="ACL3F5_000468"
     CDS             complement(38149..40362)
                     /gene="pnp"
                     /locus_tag="ACL3F5_000468"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0514324.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEAYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(41049..41915)
                     /gene="metF"
                     /locus_tag="ACL3F5_000469"
     CDS             complement(41049..41915)
                     /gene="metF"
                     /locus_tag="ACL3F5_000469"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0514325.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNSISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(41979..44228)
                     /gene="metE"
                     /locus_tag="ACL3F5_000470"
     CDS             complement(41979..44228)
                     /gene="metE"
                     /locus_tag="ACL3F5_000470"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0514326.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(44489..44755)
                     /locus_tag="ACL3F5_000471"
     CDS             complement(44489..44755)
                     /locus_tag="ACL3F5_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0514327.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVRLEQGKS"
     gene            complement(44839..45327)
                     /locus_tag="ACL3F5_000472"
                     /pseudo
     CDS             complement(44839..45327)
                     /locus_tag="ACL3F5_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            45483..46484
                     /locus_tag="ACL3F5_000473"
     CDS             45483..46484
                     /locus_tag="ACL3F5_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0514328.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(46552..48957)
                     /gene="pheT"
                     /locus_tag="ACL3F5_000474"
     CDS             complement(46552..48957)
                     /gene="pheT"
                     /locus_tag="ACL3F5_000474"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0514329.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAIFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GVGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNFALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(49034..49543)
                     /locus_tag="ACL3F5_000475"
     CDS             complement(49034..49543)
                     /locus_tag="ACL3F5_000475"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514330.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(49543..50589)
                     /gene="pheS"
                     /locus_tag="ACL3F5_000476"
     CDS             complement(49543..50589)
                     /gene="pheS"
                     /locus_tag="ACL3F5_000476"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0514331.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14328 a        11621 c         9620 g        15333 t
ORIGIN      
        1 agtccacgtt tttcaaggac tggttttgat atagcacgtt taagtaccga cttctgagct
       61 actatagtag attgaaacta gaatagtaca tctcttcttc taaaacattg ttagaaatcg
      121 atttggctgc cctgatcgat tcgtcctact cttatttcat tttactataa ttgatagtgg
      181 tcgccccagc cagatacctt atccgctata taggccttat tatcatgttc ctgttcgtag
      241 agccacgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca gacttgggaa
      301 tcgctattgg gttcaccggt agcaggtgcc caccgaggac ttacacctca aatatataat
      361 aaaatgaaat aagagtagga cgaatcgatc aggacagtca aatcaatttc taacaatgtt
      421 ttagaagaag agatgtacta ttctagtttc aatctactat acaacatgcc cgtcgtacat
      481 caaaaaaagt tgagacatag cgtcttcaac ttttttacat tactttaact actgattaaa
      541 gtgagtttac gtcaactttg ataccaacac cttgagtagt tgtgatagtc aagtttgtta
      601 cgtaagttcc tttagctgta gctggttttg ctttttggat tgtttcgttg aaagctttaa
      661 agttttcaac caatttttca gcttcaaatg atactttacc gatgattgct tgaacgttac
      721 ctgcacggtc agcacggtaa gtgattttac cacctttaga ctcttcaact gctttagcaa
      781 catccattgt tacagtacca gttttagggt ttggcatcaa gttacgtggt ccaaggacac
      841 gtccaagacg tccaacaaga gccatcatat caggtgtagc gataactacg tcgaagtcca
      901 accaaccgtc gttgatttta gcaacaaggt catcttcacc aacaaagtct gcaccagcag
      961 cttttgcttc ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa gttttaccag
     1021 taccgtttgg caataccatt gctccacgga tttgttggtc agctttttta acgtcgatgt
     1081 tcaagttgta agcaacttct acagttgcat caaattttgc aaagttagtt tcttttgcaa
     1141 gtgttacagc ttcttctaca ctgtatgctt ttgtgctgtc gattttctca agagcagcac
     1201 gaagttgttt gcttttttta gccattttct attctccttg taagtggttc aatcgatttt
     1261 catctcccac gtcacttctc gaaatgatga agtcttgcgg gttttcagtc tactattttt
     1321 ctcttcctac ggccttaagc tcccttgctg tacccaagta caagcctcag tcacttgcct
     1381 agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt gattagtcaa
     1441 caacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcattgca gactctacgt
     1501 ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt gcacgagtaa
     1561 ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct gcagcttttt
     1621 tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta tcttcgtaaa
     1681 ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg ttgaactctt
     1741 ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc ggtggagctg
     1801 gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt ttagccattt
     1861 ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca caagtatgtt
     1921 tttcacatac ccatccatta tacactattt atctggaatt gcaagagaaa agtttatttt
     1981 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaaatac
     2041 agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacactgttt tgaggttgtg
     2101 aatagaaccg acgcagtcag taggtaaggc gacgctgacg tggtctgaag agattttcga
     2161 agagtattaa tcgacgtagt ctccgccttc aaagccatag tattcttcca aactgagacc
     2221 gcttgcagca atttctttag cttcttttcc tacataacgc aggtgccatt cctcagccat
     2281 atagcctgtt tccttttcct tgcctttgag ataacggaca acaaagccat aatcagctgc
     2341 atggtccaag agccattggg ctgctttttc ttctgtcacc aaatcaccat cagtcccaat
     2401 cacatcaaag gccaagcctg tctggtgttc gctatagcca ggacgggcag agtaacggtc
     2461 agctgctgcc tttccatctt ggttgacata atcttgatag agcttggtct gagtttcata
     2521 acttctaaaa ccactgtaat gatcactaat agggaaacct gcctcttgca tggctttgat
     2581 gagtttgacc aactctgcct tggctgttgg attttccccg ggattatagt ctttcgacaa
     2641 aggataatgt ttattggcta cgatgatttc gtcgtatttt ccttggatgc tgtagtaatc
     2701 acctttattg accacttctg cttttttctg ggcagcccct tgagacttac tgccgactgt
     2761 cccatcagct ttggctgtct gttctgtctt agctgtacca tcttcatttt ttgctttttc
     2821 ttgtgaacaa gctgctagac tcaaggctag caaggctgtc acgacaaggt atcttttctt
     2881 catttctact cctttatttc taatagttta tctacttctg atgataaacg tttgactaat
     2941 cttttgatct catccggttt tgcttggcag gtttctgctg tcatttcttc aaaaggaacc
     3001 caccaaactg gaccacgtcc cttgagaccg tgaccattca tatcacctgt ccgtcgtgga
     3061 aacagatgcc aatgaagatg ggcatcgcca tttcctaaaa gttcaatatt cattttctca
     3121 gcagtaaagg ccttagcaac tgcctcttgg actagactca tttcttcgag aaaacgtagt
     3181 cttgtttcct tttctaaatg gtgcaattcc gtgacgtgtt ccttggctag aaagagacta
     3241 tagcctgcaa aatactggtg atctccaatc acaagatagc ctgtttccaa ctctttgaca
     3301 aaatagggat tttctccctt cttgatgagc tcaattctct ggcatataag acacatatta
     3361 gtctaccaac gcgctcttaa tgtaagcatc aaccatacgc tctgttgcga ccaccgagtc
     3421 aatatgagta cgctcataag aatgactaga ctcgataccc gcgccaagga gggcgtgttt
     3481 gacctctgcc cctgcggaca tggccgctga agcatccgaa ccataaaatg gatagatgtc
     3541 cagcttaaaa ggaatatctt gctctttcgc caaggtcacc aagtgttgac ggaagtcata
     3601 gtgataaggg cctgaggcat ccttgacaca gatagacact gtgtactcat ctgtttgctg
     3661 gccatcgccc atagctccca tatcaacagc cagatattcg actacctgag caggaatgtt
     3721 agaattagca ccatgtccta cttcttcaaa aactgaaaaa gcaaaatgag ttgttactgg
     3781 caattcaatc ttctctttct tataaatacg aagcaggttg agcaaaatcg ctgcgctgac
     3841 cttatcatcc aaatgacgag acttgataaa acctgtatca gtcacaacag ttcgtggatc
     3901 gaagctgata aaatcaccga cctcaatccc aagagcacga gtttcttttt cattgcttac
     3961 ttttacatcc aaacgcactt ccatattgtc ctgcgtgcgt tctgcagttc ctgcatcctt
     4021 gtagacatgg caagaagttt ggtggatgag gatggttcct gatacctttt gacctgtgct
     4081 agccacatga acggtacagt tttcaccttc aatcatgttc caaggaaaac caccgatacg
     4141 gtccaattta agacgaccat ctggtttgac agcacgaaca atagcaccca gcgtgtccac
     4201 atgggcagtc acatagcgat gttgctcatc attttgacct ttgatggtca cattgacacc
     4261 acccttggct gtgcgaactg gctggtaacc aaaaccttct agagtcttga ctaaataatt
     4321 cgaaatttca cgagtgaagc ccgttggcga tgcgatggct gtcagttctt tgatatattc
     4381 tactgtttga ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga
     4441 taaaaaaaga aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca
     4501 tttcaaaaac atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa
     4561 tggctggcac caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg
     4621 caagaaactc aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca
     4681 cagcaattgt caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa
     4741 tcataacgat agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga
     4801 taatcgcatc aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat
     4861 aaaccttgta gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca
     4921 aaccaacagt cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg
     4981 ttgagccaaa gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct
     5041 tcatcgcttc agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag
     5101 cgctgaaggc aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct
     5161 tacttgaaaa tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg
     5221 caagggcgtc caaggtatta taaccttcta ggaaacctgt accaaaggca gaagcttgat
     5281 aagcagctga agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca
     5341 agataacaat caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt
     5401 ttgatggatt aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca
     5461 agccaagtcc tttatttgca tccgacaaaa gggggctaat ccctacttcg taagctgttg
     5521 tagcagtacg tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa
     5581 gagtcgcaaa ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta
     5641 gcgttccaat aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga
     5701 tggcaggaag aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc
     5761 ccgcaccaaa aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa
     5821 aaatctcctt tatatttata aaatactgac ctagtatacc acgattagga gtctgaaaaa
     5881 agcatcacga ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa
     5941 ataaaactct cctacccagt ccacaccaag taggagaaat gcaaaatttt aaagttcttc
     6001 aaaggctaac atgccaccct ggacattgat aacattataa ccttgttcta acaggaattg
     6061 gcaagcacgc gccgatctca ttccagattt gcaaataata taatgcaagc gatctttgtc
     6121 caattaatca taactatcag ccaattgact aagcggtagg ttgtgggcac attctaaatg
     6181 aagagctgca aactcatcca cttctctcac atccactaga gaaagctggt cgttttggta
     6241 aagctggtaa aatgcgtcaa aggctatttc tttcattctt tttcttctaa tactcttcga
     6301 aaatctcttc aaaccacgtc agcgtcgcct taccgtgcgt atgttaccga cttcgtcagt
     6361 tttatctgca acctcaaagc tgtactttga gcagcctacg actagcttcc tagtttgctc
     6421 tttgattttc attgactata aaatggtttt aattcttttt ttcaaatctg gcactacttc
     6481 tgcctcaaac caaggatttt tggccatcca gatttgattt cgtggtgatg ggtgaactag
     6541 cggaaaatag gctggcagat agtctttata gtgtttcacc ctctccgtta ccttcccact
     6601 gattttctcc tgtaatctgt atagctggca ttctgtgaat ccgccatgat agcctgtttg
     6661 attctttcga tttgagacat ctactttccc tccaaaaaga agtccaagca taagatctca
     6721 gacttctatc gttttatttg atcaattcgt aaatagcttc ggcataaatt gctgctgctc
     6781 ggaaaagatc atccaaggcg ataaattcat tggcttggtg catggtatca atcgagtctg
     6841 ggaacatagc accgtaggca actccgcgtt ctagcaagcg accaaaggtt ccaccaccga
     6901 tgacttgttc atgaccttta aggccagttt gtttttcata gatattcaac aaggtttgca
     6961 caagtggatc ttccattggc acatagtgag gcgtgtgacc gtgttcagac aggctaacag
     7021 aaacaactgg caagttttca aggattgact tgatttgttc tggacttgtt ccttttggat
     7081 agcggatgtt gagggcaatg gtattatcag cacttgtttc atcgaagcgg aagacgccgg
     7141 cattcataga aagagcaccc atcttttcat ccacatgagc aatcttaaga ttttcaccct
     7201 catgatcgtt caagagaatt ttacctgcga tgtcaaggta gtctttggct ggaccagcaa
     7261 agccaaactg gctgaggaag agggcaaggt aagttgcgcc attgacacct gaagcaggca
     7321 tagcaccgtg ggctgattta ccaatgatcg tcaccttgta tttgccagct tcttcttgga
     7381 gttctcctct aagtttgtgt tctgcaacaa aggcatctag tttagcttgc aagtcagcca
     7441 aatcacctga aacgactgct gttgctgatt ctggtaccat attttcacgt aaaccacctg
     7501 taaagctgtg aagacgggca gcacctgtat tttctcctgc aaagtggagg tattccgtga
     7561 tatttccttt ttcaccattg atgattggaa attcagcatc tggagagaaa ccgaaatctg
     7621 gtttggcaag tcctacgtgc tcaaagtagt agtccatgtc tgcccagcct gattcttcgt
     7681 ctgttccaac gatgaagcga actttcttag aagttggaag acccaattct ttgatgattt
     7741 tcaaaccata gtaacaagct gttgtaggac ccttatcgtc cgaagccccg cgcgcataaa
     7801 ggcgaccatc tttgatagtt ggtgtgtaag gatctgtgtc ccaaccgcta ccagcaggca
     7861 ccacatccat atgggcaaag attccgagaa cttcttctcc atcaccaaac tcaaaatgtc
     7921 ctgcgtagtt atcgacattc ttagttgggt agccatcgcg gtctgcgatt tcaaggaatt
     7981 tctccaaggc ttttactgga ccaggtccaa atggatgctg ggcatcagcc ttgctatcat
     8041 cacgttctga gttgatttcc aaaaggctaa acaagtcagc caagaggtct tctttgcgtt
     8101 tttctacttc tgctgtaaaa tcaattgctg tcattttttc ttctttctat cttttctcga
     8161 tgatttcatc tactggcaag cggtagcttg gttccaattt gtcgtctgtg taacccactg
     8221 tgatcaagag ttctgggcgg aaacggtctt cgatttccaa aacttcatta acttttgatt
     8281 tgtcaaaacc aaggataata ttggaaccaa ttccttggtc tgtaagagcg agaaccaagt
     8341 tcatagcaac caaacctgca ttgagtgcta ggtagtcgct gacttgttgt tcattgtagc
     8401 gtgcaaattc agctggcaaa tttttcatga agtattgaag ttgttcttct gagaaattgt
     8461 tagcaccacc aactcgggca atcttacgag cgcgtttggc aaggtctgta tctgtaaata
     8521 gggcaatggt tacaggtgct gatgatacct gctcaaagtt tgaaccataa gccaactttg
     8581 ccagttcagc atttttctca cgaacaacta caaatttcca aggctggctg ttgtgggcgc
     8641 ttggcgccaa ggttgcaatt tcgatagccg tacgcacatc ttttggatca acaggcttat
     8701 cagtgaaatg cttggtcgca tgacgttttt tatttaattc aagaaatttc ataatcgatt
     8761 tccttttcta attctactgc ttccattcta ccataatttg aaagagcttg cagggatttt
     8821 tcatgattaa gtttttctat cacagacata aaagatatat attggtttat taggaaagtt
     8881 tctgataaac tagcaagtac tttacatttg aatggagaca gtatgaaaaa acttagccta
     8941 ttactagcta tcctaccatt tttggttgcc tgtgggaatc aagctacacc caaagagact
     9001 agcgctcaaa agacaatcgt ccttgctaca gctggcgacg tgccaccatt tgactacgaa
     9061 gacaagggca atctgacagg cttcgatatc gaagttttaa aggcagtaga tgaaaaactc
     9121 agcgactacg agattcaatt ccaaagaacc gcctgggaga gcatcttccc aggacttgat
     9181 tctggtcact atcaggctgc ggccaataac ttgagttaca caaaagagcg tgctgaaaaa
     9241 tacctttact cgcttccaat ttccaacaat cccctcgtcc ttgtcagcaa caagaaaaat
     9301 cctttgactt ctcttgacca gatcgctggt aaaacaacac aagaggatac cggaacttct
     9361 aacgctcaat tcatcaataa ctggaatcag aaacacactg ataatcccgc tacaattaat
     9421 ttttctggtg aggatattgg taaacgaatc ctagaccttg ctaacggaga gtttgatttc
     9481 ctagtttttg acaaggtatc cgttcaaaag attatcaagg accgtggttt agacctctca
     9541 gtcgttgatt taccttctgc agatagcccc agcaattata tcattttctc aagcgaccaa
     9601 aaagagttta aagagcaatt tgataaagcg ctcaaagaac tctatcaaga cggaaccctt
     9661 gaaaaactca gcaataccta tctaggtggt tcttacctcc cagatcaatc tcagttacaa
     9721 taacactctt cgaaaatctc ttcaaaccac gtcagcttta tctgcaacct caaagctgtg
     9781 ctttgagcaa cctacggcta gcttcctagt ttgctctttg attttcattg agtataagat
     9841 atactaaaag cgattggacc agccaatcgc ttttttagtt tgcattggct attttaggaa
     9901 actcttacaa aaaatcaaaa aaattcttca catcctctac atacccatgc ttttctatta
     9961 agctggctaa taattccaga ttgtgcccct gatagttatc gtcacgacgc agttcttcat
    10021 acatttcgat aaagggaagc cccttggact tggccaattc taactcagct tcgtaatcat
    10081 aagcaacttt acgaaattgg atattgagta attccccatc ttcaacttct atcacggcat
    10141 actgggcacg gtgatttttt aacgcctccc aattaaaata gggcatgcca atcgaccctg
    10201 tattgatgat ttgttgccct tgacttccat aacgaagcaa ctgcttgtga acatgaccat
    10261 aaactgccac gtccgtttcc gcatctagca gctggtcaaa tttctctgta tcattctcaa
    10321 ctagcaagtc accaccatag tttttgtcag gtaaattatg agagatagaa aagcgcaatc
    10381 cgtcaatttc tttcttttcc agcaaaggca agcttcgtag ccagacaatc gttgcaggat
    10441 ccattcgctc catcaaaaac tgggtcatgc gcattgactg gatttctttc ggatattcca
    10501 aaccatattc gccatccaag acctcaagga cacgatcatc ccaattgcct cgaacacttg
    10561 ctgtgatagg aaggtccttt agcagggcga ctaagtcatt tgcgcctgga ccaggaagaa
    10621 aaatatctcc cagaagccaa tattcactgg ccccttgatt tttagcatct gcaatcactg
    10681 cttctagcgc cgtcgcattg ctatgaacat ctgataaaat tgcgatttta tggttcattg
    10741 tggtttcctt ccgtttggta atctactctt tcttctgcta cttgaggcaa ggcttctccc
    10801 tgcgggttca actttctttg cacagcctct gcaacgactc taggtacccc aacttcgaca
    10861 atctcatcca cactggcttc cttgattttg gtcaaagact tgaaatgctt cataagattc
    10921 tgcttgcgtt taggtcccag accgtcaatc ccatccaatt gagatgagaa agaatttttg
    10981 gagcgcagtt ggcggtggaa agtgatagca aagcggtgca cctcatcttg gatgcgttgg
    11041 aggaggaaaa attcctgaga attgcgagac aagtccacca cctcaagcgg atctccaaag
    11101 agcaattcat gggtttggtg cttatcattc ttttgcagcc cagcaattgg aatatccaag
    11161 cccagttcct cttggataac ctgcttagcg atattgactt gaccttgccc cccatcaatg
    11221 acaatcaaat ctggaggagt caaagcctca cgctgtactc gaccatagcg tctgcgaatg
    11281 acctctctca tgctggcata gtcgtctggt ccaacaaccg tttttatctt gtacttacgg
    11341 taatccttct tactcggttt accgttgaca aagaccacca tagccgaaac agggctagtt
    11401 cccatgatat tagagttatc gaaggactcg atacgtactg gggtcgggat ttggagcaaa
    11461 cgccctagat tttcaatagc tccttgagtc ttttcgacag atttttctag cagattgaac
    11521 ttctgctcta gactaacacg agcatttttt atggctagat tgaccagttg ttttttctct
    11581 ccacgttgag gcttaagaat cttggaatcc accaaggcct tgacagcctc ttcgtcaata
    11641 tcctgcggaa tcagtacctc attgggaact agatgagatt tttcttgata gaattgtcct
    11701 acataggtca aaaaatcctc atctggatca ttgaagtagg ggaagagatt gacatcgcgc
    11761 tcgataagct taccctgacg gacaaagaaa acctgcacac acatccagcc cttatccaca
    11821 tagtagccaa agacatcgcg attttgcaaa tctttcgcca tgacccgttg cttggttcga
    11881 agcgttccaa tagcctgaat caggtcacgg tattccgccg cacgttcaaa ctccatactt
    11941 tgtgctgcta ctgccatttt actcttgaga tcatcgatga ttttgtcatc ctgacctttc
    12001 agaaaatcag acacctcctg agccatagac ttgaaataag cctcatcctt cttacagatg
    12061 gtgtgggcca tgcattgacc gatatggtaa taaaaacaga ccttagaggg cgggttggta
    12121 cacttacgaa aagggaatat ccgatccagc aaccgcttga tttcattggc tgcccccaca
    12181 tcgggatagg gtccaaaata aagacctccg tcctttttga cctgacgagt gataatcaag
    12241 cgtggatagc gctcattggt gattttgatg aaaggatagg acttgtcatc cttgagcatg
    12301 atattgtact tgggcttgtt ttccttgatc aggttgattt ctaggagaag tgcctcaata
    12361 ttagactccg taacaataaa ttcaaaatcc acaatttcag acaccagagc ctctgtcttg
    12421 gtatcatgac ttccacgaaa ataggaccgt actcgattac gcagattttt agcctttcct
    12481 acatagataa tggtgccatt tttatcctta tgaatgtagc aaccagggct ggtcggcaag
    12541 agctctagtt ttgatttaat caagttgttc atagttccat tatagcaaaa aagtagggaa
    12601 agatagtacc ctactcacta gtctcatata tttttcggag gtttgcaaca tcctcttcct
    12661 ggataccata aaaggaacct gctggttgca tgacagactt ctcatctgta tggtccaagc
    12721 caatcgcatg acctaactca tgttctgccg tatggacaag gcgttcatag gagtagccat
    12781 agtatggatt ggacaaataa taatgattca accgcaccgt tacggacaag aattgccctg
    12841 ttaagagatt agtttgactt tccgcctctc ctgccacagg agtgcctccg tcgttcatct
    12901 ccgtagccgt aatatccgcc ttactagact cagtcacgag ttcaaagtta aaagcaccag
    12961 tttgattcca gttctggatt gcttctaaat aagcctcttg aaagcgtgaa tccatctgcg
    13021 gatccaggta aatacgagca gaggcctgtg cccaccttcc ttcagaatgc tggtgactat
    13081 ctgtctggct taacttaggc agttgccctg ttttctccca ttggtcaata ctttgttgac
    13141 caatttttac tgaccgttct gcttgcttta gcgctccttg aaaatccccg ttcagatacc
    13201 agagaagtcc gaaagcaagc acacataaga gcacaactat ccaaaccaga cgccaaaaca
    13261 aacgccacac aaaagaaaag aaaagaaagc ccctatcaaa cgaaaaagcc agcgcatgtc
    13321 tctccacctt tctagcaaat aagaattatt ttactaaaag aagctaaaag aaatctaaat
    13381 actgactttt tcatcttaac gtcctactat ttttttgagt aactggatag ctttgtattt
    13441 taaaggcgat ggatggtaac ggaaagtacc cgctttgcgt acaatatagc cattaaaatt
    13501 ctgtttaaaa cgcaaaacac catcacttcc atcaaaaatc ccttgaatgc ctaggaagtt
    13561 gtatttaggt attccacgtt ttatgctttc caacataaca tatttttgaa gcagggcagg
    13621 ggcatagaac ttattaaact cagtgtagga accactaaag agataagtcg tttcctgagg
    13681 catataaaca aataaactcc cagctaaaac aatatcttct tctccatatt tttcaatcaa
    13741 gtctcgcgct tctgcttttc gaacttcaaa cgtttcaaat tgactagaat attctctcag
    13801 ttgattttgt tttttttcag aatgaggatt tttactcaaa tcaagtcgca acttgtccaa
    13861 gttttcttct agtttacttt gttcaccttg caatttgctc atatactccg aaaaattcaa
    13921 gcttgctatg agaaactccg cttgttctcc aaaagtatca taaaaatgct cataatattc
    13981 taaactttta tcactatatt ctctacgttc agaggtttct tttgttatat tcttaaaaat
    14041 cgatagttct tcacgtttta actttttcaa ccgaatgcca aaggtttcag cctttttcac
    14101 caagggttta ccctttttgc taaaactttt aagcaaactc ttttcagtta attcagttaa
    14161 atctttatag tataaccaat ctggttctcc acctgggtaa cctgttgtta agccatcaaa
    14221 ttgataacct aaatcagtca aaccttgaat aatacttttt ttctcagcat ctattggatt
    14281 accttggcta tcaaaagttt gataagtttc ataaggtttt acaagcaact ctaatacacc
    14341 attttgcttg gcatattctt ttaactctgc ataaaaaact ggaagagcat cttgttgggt
    14401 ataaatcggc cccgaattga gttccatatg cagaccaccc agcatgggca agctataaac
    14461 cagagctgca acttgaattt ctccttcttg tttcaaagca agataaacaa ttcgagcccc
    14521 tcttttttct agcaaatccc ccatctggac agattgcata aaggaacgag aagaaacctg
    14581 atcagaataa gtctgaaact cttctttcgt gagtgttgtt agtgccatat acttactttc
    14641 tatgtttttt tcttaatgtt ttacggaaat caagagcaag tcttaacaga ggatagagag
    14701 gatgagtggg cattgtaaat tcacccaagt attcttcaat cgttggatta aatttttcct
    14761 taaaatgata aagtccacca ttgagagagt tttcaacacc acctaaattt tgccagacca
    14821 tacctcgctc aaaggcatag cgagccgttt cataccatgt taaaattggt gcattgtaac
    14881 gtttaaaatc atcatccata ccagcatata tattgacaga ggtagtacca aattccaaac
    14941 tcaaagtagc cgctaaagga actctcgctt gacctacatc tatatattcc tgcaagaagg
    15001 tcaattcctc taacaaacgt tctttttcct tcttctgcgc ttctactttt gaagttcgag
    15061 tcgactcagt aaaggtctct tccaaggctc tatttttcgc taactgttct tctaattctt
    15121 gcgaacgttt agaaacatcc aaggtggcca aggtgatata ggccttgtcc ttaaaattat
    15181 ctaacaattt tttataatag gcttcattcc tcaaatgaat ctcttttcgc ttctcagttt
    15241 ttttcatcag ctccgaaaat gaatctaata gttccagtcc accatattga atctcaagcc
    15301 ctttgtttcg tgctgttcga atagcctgtt ttgttgactt ggaaagttta tcttcttcaa
    15361 aattttcctt gtatattttc gcctgaatac gaggttgaat ggtgtctccc atttcctccg
    15421 tttttcctga ccaccttact cccatttgtt gcaaactatc aataatagcc agattttcag
    15481 gaaattctgt cttttcctga ttgattaaac tttgagatag gcaaatactt gggtcaaaag
    15541 tcacaaaaac cactctctta ctgcgagcat aggacttaat agactgaatg gcaaaattca
    15601 agagttcttt atccccataa tccaatatag gtcctcttgg gatgtaaaac attttatagc
    15661 ctagcggaag agttctaatc aaaatactag ctgtcgccag taatttttct tccctgtaaa
    15721 caccaaactt ctcatgttgc caattagact taacttcctc ccaagcacta ctttgtaata
    15781 cattggctaa ttcatgttct ttgacaaact gatcatattc taatgtggga atgccaattt
    15841 gataacggta catttcctac tctctttcct ccagtatttt attactattc tactactttc
    15901 gtttgaaaag tctagtgaaa acatatttta tttcagttct actcccccta tgctgaagtt
    15961 caaactaagt cagtctctct tctaatttga aatcaattgg tagggttgtt aaaaaaactt
    16021 ccaattgttt ttcccagtag taccactcgt gagttccagc gctatggcta taggtcacat
    16081 caaaacctag ttttttgaga tttttcactg cgagattatt ggcttcgtac aagaaatcct
    16141 gttcgccaca ccacgcccaa agtttggtct ttttatccga ttttttagcc agactttcaa
    16201 gagaataggg actagttgtc cagtctctaa tctctccaaa aacacctctc cagtaggctg
    16261 gacttcccag attttgactt tcaggagaaa agttttgaaa gctgagggca cctgaaaaac
    16321 tagctgcatg agaaaaacga tttgtcgtaa gagccagttt gaagcagccg tagcctccca
    16381 tagaaagacc agcgataaag gtcttttcac gcttgctcgt catattaggg aagaagcgtt
    16441 tcagaacctg tggcaattcc tctgctagag ccgtgtagta gtcaaaacca tactgggtat
    16501 cggtgtacca accattgctg gtattgggca taacaacgat gagattagtt cctcgaagca
    16561 agcgttctac attggtccgc ttaagccaac tattatgatt tccagacatc ccgtgcaaaa
    16621 ggtacaagac gggaatatct tcacactctg gttcttccac tcgattggca tcagggtaga
    16681 ggacattcac cccccactcc atatccaata cttgtgagta atactcgatt ttcattactg
    16741 ccatgatttt ctccttctat ttttctataa gaaaaagccg aaactcgact ttctctctgt
    16801 ttatttcaac gattattttg cttccatgac tactggtaaa atggctgggc gacgcttggt
    16861 ttgatcaaag aggtacttgg tcagattgtc acgaacctta cctttaagat ctgcccagtc
    16921 aaagtcatct ccttgaagat aatcttctac cgtttggtta atcaattctg aactttcacg
    16981 gagaatatcg cgactcttct tgagataaac aaatccacgc gtgtgaacac gagccctagc
    17041 cacaattttc ttctcacgac ggttgactgt aatagccacg atgaaaattc catcctctga
    17101 caagacctta cggtcacgaa gaacaacatt tccaacatca ccaatggcat tcccatcaat
    17161 caagatatct cctgctgaaa ccgatccagc tggaacaaag tctccattct cgtaagccat
    17221 ggtcgtcccc tttttaggaa tgaaaatgcg ttctggcaac atcccaactg ccatggcagc
    17281 cttagcgtga gcatccaact cacgatactc cccttggaca gggaagaggt acttaggttg
    17341 caaaagattg atcatcagct gcaaatcacg cacatttccg tgccctgata catgtaaact
    17401 ttgggtaatc aatttgacaa ccccacctgc ctgataaatc atattttcca cacgcgcaac
    17461 aaaggcttct ttagcaatag acggagccgt agcaatatag accaggtccc catccttgat
    17521 ttctacataa cgatggcgac caatcgacat cttacgaagt ccattgatag gttcacccat
    17581 acgacctgtc tcaagaataa tcaactcatg gtcttcaaag cgagacatat ctttaggctt
    17641 aatcaagaga atttcgttgg ctaaagacaa cttcttaaga cgaatcgctg tgcggacgat
    17701 attttcaata tcaaatcctg tcaagacgat acgtcgacct gttttatccg cagcgtcaaa
    17761 aatctgctga atacgagaaa gattactgga aacagctgca acgatgatgc gaccttccca
    17821 gtcagcaata gtttgggtaa tttcatccct aacttcactt tcactagcca cctgaatatt
    17881 gctgtctgca ttggccgaat cactgaggag agccaggacg ccgtcacgac caatctctgc
    17941 caaacgagca aaatcagttg cataagattc actagccgtt tggtcaaatt tgaagtcacc
    18001 tgtataaacg atgcttcctt ccgatgtctt caagacaatt cccagactct ctggaacgga
    18061 gtaagtcgta gggaagaagg aaaccactgt cccaccaaaa tcaatctccg tattctcatc
    18121 aatgacatgg aaatcattaa atttcttaac ggcatcattt cctttgacaa agagctttgc
    18181 caactcaatg gtcaactcag acccaaatac aggaacttta gcctctgcca agagataagg
    18241 tagagcacca atggcatccg catgcccgtg ggtcaagaaa accccagcaa tacggtcgct
    18301 attttcaaaa aggtaatcca tgtttggaat caccacatcg acccctaatt gttcattttc
    18361 aggatatttt aaccctacat tcaaaacaaa aatggactct ccaatttcag caatgtacat
    18421 attttttcca ttctcacgca caccaccaag tgttgttaaa ctgatattac tcatttttcc
    18481 tccaaaatct tagtttatct tgattatagg gcaattctac cctcttattc taaaagttct
    18541 gatactttca gccgaatctt ttcctaccat tataccattt ttttgatgat tttcaaaatg
    18601 aaggtctgtt ttcaaaaaag agttgatttc ccaactcttt cctaacttct actctttttc
    18661 catcaaaaaa tcataaattt cttgcaccgt acccagcgcc atcatttctt ggtctttaac
    18721 ggtttgtttg agattttggt aaatttgact ttctcctatc tcccgctttg gcgcctcttt
    18781 attgactgtc atcacaccat cttttatcgt cacaaagcct agttcttcaa atacttgaat
    18841 catcttgacc agcaagattt gttgaatatt aagatatgca gccaaatctt tcagcttgta
    18901 gcgaatatca aactctggga actggtaaat agtcttgtac aatttggcaa actgatctct
    18961 agtcccataa cctgtcagat aataagcctt gtcaatatca tttttgaaat agacagcaga
    19021 gaaatgctgt tcctgaaaaa tggtcttcag ctgagtaata tcctctggaa tgttttttac
    19081 gacaacagct tcactagccg caagatttgg cagttctcca ggaaaatcca agactggaac
    19141 accttctggc aagactgcat tttttccacg aatgttaaaa agttgaacac cttccactcg
    19201 cgcatccacc atcatcaact ggagggcagt ttggccattc cattggttga cagacaattt
    19261 aaccgctaac tctagattct tggtttgaga aaactctgtc gcccatctgc cttgaccaaa
    19321 ggctaccact tcaaaactcg cctcaccctt ggaaattttc agctttagat gggcattacc
    19381 tgcccccata gtacgagcac tttcgacctg aaaattcttg atataaaaaa taggtttctg
    19441 attatccatt ccaaaaggag ctaaacgttc aaaacttttg accgtttcca agctaagtgc
    19501 ctccaaatcc aactcttcat ctaggtttaa cttattcttg ccaccagcat ctgcaccttt
    19561 ttcacgaaca taatcttcca aaacctgaga taaatctgag agttgctcaa cttccagcgt
    19621 catacccgct gcacctgcat gacctccaaa ggcgatgaag aggtctcgat ggggatccag
    19681 agcttcaaaa atatcgaccg cttccacact acgagcactg cccttggcac gaccgtcttc
    19741 tatattaaga acaatgactg tctgtcccaa ttcttccaat aaacgaccag ccacgattcc
    19801 tagaacccca ggattccagc cttccttggc caagacctga accttcttct caggatccac
    19861 catggtcttg gcttcttcat agatagactg aacgatttcc ttgcgctctt cgtttttctg
    19921 gtgaatcata agggcaatct catgcgcttc ctcatcatca aatccagtca acaaatcaat
    19981 ggcaggattg ggatcatcca agcgacccaa ggcattcaaa cgaggagcaa tctggaaacc
    20041 aaccgtttct tctgttactt cgttggcagc aatcccagcc atgtccagca tttcttgcag
    20101 accaatgcgc tgggtatgac ccaacatttc cagaccatat tgaactaaga tacgattttc
    20161 atccgtcaga ctcaccatat ctgcaatagt tccaatagcg accaaatcaa gcaattccac
    20221 ttgcacttct tctaacaggg cacaagccaa cttgaaagca actccacaac cagccaaata
    20281 tttaaaagga taatccgcat ctggatgttc aggatggaca atagcataag catctggcag
    20341 ggtttcaggc atggaatgat ggtctgtcac aatgacatct actcccatag actgagccaa
    20401 tgcaatagcc tcatgaccag caaccccatt gtccaccgtc acaatcaagg aaatcccttc
    20461 ttgctcgata aagtatttat aaacactagc attagggcca tagccatcgg taaaacgatt
    20521 tggcaggtaa actcggcact cagcaccaag ttgttccaaa ctttccttca caatagaagc
    20581 cgaagtcatg ccatccgcat catagtctcc ataaacaaga atattttccc cttcttcaat
    20641 agcctgacga atccgctcca ctgccttgtc catatcatgg agcagataag catcatgtaa
    20701 gtcctccaag gaaggttcta aaaacttctt cagactttct tggttctgaa tccctctctc
    20761 aaacaataac cgagccacct caggacccag tccagccttc ttggctatct ttgtaaaatc
    20821 cgcatcttct acctgcaggg caaactgcca ttcataagta ggtgttatca aaaagacatc
    20881 cactctttct aagaattcta ttgcttcatt ataacatgat ttagacgttt tctctatcca
    20941 gattgctttt ttataacatt ttatagtata ttgaaactag aatagtacac ctctacttct
    21001 aaaatattgt tagaaatcga tttgactgtc ccgatcgatt tttcctgttc ttatttcact
    21061 atagtgaatt ttttcagata tggtttgaca agaacattct tttattgtag aaccgtgtta
    21121 taaaatataa cacaacagag atctctcatg gctttagtag aatttaaaaa cgtcgaaaaa
    21181 tattacggag actaccacgc attccgcaac atcaatctcc gttttgaaaa aggacaagtt
    21241 gttgtcctgc ttggaccttc tggctctggg aagtccactc ttatccgtac gatcaatggt
    21301 ttagagactg ttgacaaagg aagtctccta gtcaatgggc accaagttgc tggtgccagc
    21361 cagaaagatt tggtacctct tcgcaaggaa gtcggcatgg tttttcaaca ttttaacctt
    21421 tatccacaca aagctgtgtt agaaaacgta acgcttgcac ccattgaagt tctaggaatt
    21481 gataaaaaag aagctgaaaa aaccgcccaa aaatatctgg aatttgtaaa tatgtgggac
    21541 aagaaagatt cctatcccgc catgctatct ggtggacaaa aacagcggat cgccatcgct
    21601 cgtggtcttg ctatgcatcc ggaactcctc ctctttgatg aaccaacatc tgctcttgat
    21661 cctgagacta tcggagatgt tctagcagtt atgcagaaac tggcgcatga tgggatgaac
    21721 atgatcatcg ttacccacga aatgggcttt gctcgagagg ttgcggaccg cattatcttt
    21781 atggccgacg gagaagtttt agtagatacg acagatgtcg ataacttttt tgacaatcca
    21841 agcgaacctc gtgcccaaca attcctcagc aaaattatca accacgaaag tgacaaagtc
    21901 aaataaggag gcgcctatga aaaaaaaatt ctttttatca gcattattga ttagcctttt
    21961 cggccttgct gctgccaaac cagtccaggc taatactagt atcgcagaca ttcaaaaaag
    22021 aggcgaactg gttgtcggtg tcaaacaaga cgttcccaat tttggttaca aagatcccaa
    22081 gaccggtact tattctggta tcgaaaccga cttggccaag atggtagctg atgaactcaa
    22141 ggtaaagatt cgctatgtgc cggttacagc acaaacccgc gacccccttc tagacaatga
    22201 acaggtcgat atggatatcg cgacctttac catcacggac gaacgcaaaa aactctacaa
    22261 ctttaccagt ccctactaca cagacgcttc tggatttttg gtcaataaat ctgccaaaat
    22321 caaaaagatt gaggacctaa acggcaaaac catcggagtc gcccaaagtt ctatcaccca
    22381 acgcctgatt actgaactgg gtaaaaagaa aggtctgacc tttaaatttg tcgaacttgg
    22441 ttcctaccca gaattgatta cttccctgca cgctcatcgt atcgatgcct tttccgttga
    22501 ccgctctatt ctatctggct acactagtaa acggacagca ctactagatg atagtttcaa
    22561 gccatctgac tacggtattg ttaccaagaa atcaaatacc gagctcaacg actatcttga
    22621 taacttggtt actaaatgga gcaaggatgg tagtttgcag aaactttatg accgttacaa
    22681 gctcaaacca tctagccata ctgcagatta aggaggacac cccatgacag atttatcatc
    22741 ttggacagcc tattttcagg attttggaca atttttcaat ggtttcctct tcacccttgc
    22801 cctagcggtt ggttccttta tcctcgctat ggttttgggc atcttctttg gagccatgtc
    22861 aaccagtaaa cgtccgattt tgcgaatctt agctcgcatc ttcgtggaat tttaccaaaa
    22921 cactcccctc ttggtgcagt ttgttattgt tttttatggc ctacctctta tcagtgacca
    22981 tactatcatg attccaattt attggacagc tgttctctgc gtgggactct atcacggcgc
    23041 ttatatcgct gaggttattc gttcagggat tcagtctatt cctagtggtc agatggaggc
    23101 cgccttgtcg caaagtttta cctatatcag tgccatgcgc ttgattacct tgcctcaggc
    23161 cttccgcatc attctccctc cattgaccaa ccaaattgtt aacctcatca agaacacctc
    23221 tactgtagct atcgtctctg gagtagactt gatgtttgtg actaagtctt ggtcggctct
    23281 caacggaaac tatatcccag gctttttagg tgctgctctt ctctactttg ccctatgctt
    23341 ccctgttgcc cagtttggtc gcaagatgga gcaagccaac aaaaaagcct attcacttta
    23401 ggaggttact atggaatcta ttttagaagt tttaacccca gataacctag tctttatatt
    23461 taaaggattt ggcttgaccc tctatatttc tctgattgcc atcatcctct ctactatcat
    23521 cggtacggtg ctagctgtca tgagaaatgg caaaaatcct atcttacgca ttatttccag
    23581 tatttatatc gagtttgtgc gcaacgttcc caaccttctc tggattttta ctatcttttt
    23641 ggtgttcaaa ataaagtcca caccagcagg tattacagcc tttactctct ttacatcagc
    23701 agccttggct gagattattc gaggcggtct caatgccgta gacaagggac aatacgaagc
    23761 aggaatgtca caaggcttca cctcagccca aatcctctac tacatcattc tcccacaagc
    23821 catccgcaaa atgctaccag ccatcatttc tcagtttgtt accgtgatta aggataccag
    23881 tctcctctac tctgttatcg ccctacaaga actctttgga gccagccaaa ttctcatggg
    23941 ccgttatttc gaaccagagc aggtcttcag tctttacatc ctgattgccc tcatctactt
    24001 cagctttaac ctagcaattt ctagcctgtc tcatatgcta gccaaacgtt ggcaacaagc
    24061 tgcagaataa cactcttcga aaatctcttc aaaccacgtc agctctatct gcaacctcaa
    24121 aacagtgttt tgagcaactt gcggctagct tcctagtttg ctctttgatt ttcattgagt
    24181 ataaacagcc actctccagt tcaattggag agttttttga tgagagtaga tatttataga
    24241 cctcaatttg acaccataca ttttctatga taaaatgtaa caaatttatt tacaacaaat
    24301 cgaaatctaa atgaaatgga attttctatg aaatcagtca aaggactact ctttatcata
    24361 gctagtttta tcttgactct tttgacttgg atgaacactt ctccccaatt catgattcca
    24421 ggactagctt taacaagcct atctctgact tttatcctag ccactcgtct cccactacta
    24481 gaaagctggt ttcacagttt ggagaaggtc tacaccgtcc acaaattcac agcctttctc
    24541 tccatcatcc tactaatctt tcataacttt agtatgggcg gtttgtgggg ctctcgctta
    24601 gctgctcagt ttggcaatct tgccatctat atctttgcca gcatcatcct tgtcgcctat
    24661 ttaggcaaat acatccaata cgaagcttgg cgatggattc accgcctggt ttacctagcc
    24721 tatattttag gactctttca catctacatg ataatgggca atcgtctcct tacatttaat
    24781 cttctaagtt ttcttgttgg tagctatgcc cttttaggct tactagctgg tttttatatc
    24841 atttttctat atcaaaagat ttccttcccc tatctaggga aaattaccca tctcaaacgc
    24901 ttaaatcacg atactagaga aattcaaatc catcttagca gacctttcaa ctatcaatca
    24961 ggacaatttg cctttctaaa gattttccaa gaaggctttg aaagtgctcc gcatcccttt
    25021 tctatctcag gaggtcatgg tcaaactctt tactttactg ttaaaacttc aggcgaccat
    25081 accaagaata tctatgataa tcttcaagcc ggcagcaaag taaccctaga cagagcttac
    25141 ggacacatga tcatagaaga aggacgagaa aatcaggttt ggattgctgg aggtattggg
    25201 attaccccct tcatctctta catccgtgaa catcctattt tagataaaca ggttcacttc
    25261 tactatagct tccgtggaga tgaaaatgca gtctacctag atttactccg taactatgct
    25321 cagaaaaatc ctaattttga actccatcta atcgacagta cgaaagacgg ctatcttaat
    25381 tttgaacaaa aagaagtgcc cgaacatgca accgtctata tgtgtggtcc tatttctatg
    25441 atgaaggcac ttgccaaaca gattaagaaa caaaatccaa aaacagagct tatttacgaa
    25501 ggattcaagt tcaaataagt aatcatactc tcctgggatt tcccaggaga gttttttata
    25561 gccaaatgaa ataagaccgg aacgatggaa ttttggcatt caaatcaatt gataagaata
    25621 ttttatagtg gagtgaaata ggatacgaac aaattgatta ggaaaatcaa atgaatttat
    25681 agaaatcttt tagcagttat gttgtcctgt tctagtttca aaacgctata gaaacagcat
    25741 tgtgctagtc tagattcagt ttactatact aaaacgagta gcttgaaatc aaaaaaccca
    25801 ccctcacagg caggttttat ctgtattatt cagctagatt atgctttacc ttctgaaccg
    25861 aatacgtcga tacgttcttc aaccgatgct tggatagctt ttacaccgtc agccaagaat
    25921 ttacgtgggt cgaagagttt tttcttgtcg tattctgctt cgtttgcttc gtagtcacga
    25981 gcaaatttac gagttgcgtt agcgaatgcg atttggcatt ctgtgttaac gttaactttg
    26041 gcaacaccaa gtttgatagc tgcttggatt tgctcatcag gaatacctga tccaccgtgc
    26101 aatacgattg ggaatcctgg aagagcttct gtcaattttt gcaagtggtc aaggtcaaga
    26161 ccttcccagt ttactgggta agggccgtgg atgttaccga taccagctgc caagaagtcg
    26221 ataccagttt caaccattgc tttagcgtct tcgattggag ccaattcacc tttaccgatg
    26281 attccgtctt cttcaccacc gatagtacca acttcagctt ctactgagat acctttagcg
    26341 tgtgcttttt caacaacttc tttagccaat ttaaggtttt cttcaactgg aaggtgtgaa
    26401 ccgtcaaaca tgattgaagt ataaccaact tcgatacact caagtgcatc ttcgtagtga
    26461 ccgtggtcaa ggtggatagc tactggtaca gtgataccca ttgattcaac aaggttagcg
    26521 atcaagttgc gagcaacttt gtaaccaccc atgtatttag cagcacccat tgaagtttgg
    26581 atcaaaactg gagctttttt agcttctgct gcgcgcaaga tagcttgagt ccactcaagg
    26641 ttgtttgtgt taaatccacc aactgcataa ccgttgtcac gggctgcttg gacaaatttt
    26701 tctgctgaaa cgattgccat tttatcaggc ctcctgtata tttttatggg tcatcccatt
    26761 tacattgttc attttatcac tttttgccaa aaaaatctag tttttcccgc agtttcgatt
    26821 gattttcttc taactccatc tatgtaaacc ctttctctcc ctagtcttgg acgacttttg
    26881 gaaaatctat aaagaaggtt aaacgattct cctccatctc gaaacgataa gctaattttt
    26941 catgttctaa tagactctta accacaaaga gccccatacc agaccccttg accttgcgac
    27001 tagcattgtc agaaaaagac tgggctagtt tttcttgttc ctctgagcta cagctatttt
    27061 cgataaaaag ttctccttct ctttctccaa ttcgaactaa gccacctgga acagagtgct
    27121 taatggcatt gctgatgaga ttagaaagaa tcaacttcat aactgatggg tttagataag
    27181 cctgctgatg ggtcaaacta ttgtctatct ggagctctct ttccttggct agcaaggcat
    27241 aatctttgac cagattttgc gtcatctgga ggaggtcaat tgtttcccta tcatctcgca
    27301 attcctgcac agaagagagg gaaagtatct gcagaacatg gtgattgagt tcatccacaa
    27361 tccccaaggc aactcccaga tactggtctc tatccttata acgaccgata ttctctctca
    27421 tattttcgat taggattttc aaactagcca gcggtgtttt caattcatga gaagctcctc
    27481 gtaggaattc gaccttcatc ttctccagct ggagaatggc ttcattcttt tcatgcaagt
    27541 ccgcaataac agtcaagaga tgctggtaga ggctattgat ttgttccttg agattaccta
    27601 tctcatcctt agaatccacg cgcaatcgca cttgggaatc caggtccatc atccgacggg
    27661 tcacccgctt gatttccaaa atcggtgcaa caatagtccg agcgtagatg taggccacca
    27721 agagggaaat cagaaaggag gccagcaagg tatagggaag aaactggaga ctgatttgct
    27781 ccgcttcctt ttgtaaatcc atggaagcta gaaactggag aatcatagta gcaccgtctt
    27841 gcgttttcac ctcgcgctcc tcaataaaga gagaggttgt ctggcggtct gtgtccagag
    27901 gaagactgtc cttgacttct aacttgtcct cggtcatctc acctttgacg gtccccttga
    27961 tatcactagt ctgggaatac aagtctaaca cttgctcgat actctgccta tctttccctt
    28021 ctagggactg ggcaatggct gttgcctttt gaccaatggt ttcctgacga tgactcagat
    28081 aagtcgaagg aaaaagaaaa taaatagcta aatgaaggca gataaccaga acactaaata
    28141 tcgagaaggt atagataaat atctttgcaa ataaacctgt tcgtttcatt ttcgctccaa
    28201 tttataacca acattgcgca cagtgaggat acaatccaag tctagctttt tccgcaattc
    28261 cttgatataa acatcaataa cacggtcaaa gggaacctca tctgtcgctt tccagacggc
    28321 atcgataatc tgagatcgag tcaaggcccg gccttcattt ttcactagat agtccagaat
    28381 ttccaactct ttggcattga taggcacttc ttgacctgcg atgcttgcac tgtagctttc
    28441 aaagtccacc ttggtatcct tgtaagaaaa gattcgtcct gtatcgtagt agcgcttgaa
    28501 aatcgcgtcc accctcactt ttaagaggga gagggagaaa ggtttttcca gatagccatc
    28561 tgccaaagag gcaaaggcac tcatcttgta ttcctcatcc tgaaaagctg tcaacatcaa
    28621 gacaggaacc tgactggttt tacgaatctc agctaggact tctaagccgt tgagcttggg
    28681 catctggata tccagtaaaa ccagggccac ctcatagcta gaaaattgct ccagagcttc
    28741 ctgaccgtcc gctgcctcaa tagtttcata gccacaatcc gtcaaataat cactgacccc
    28801 ctcacggatc atctcttcat cttctacaat taaaattttc atactttaac tgctctctat
    28861 tttttatttt tcttagaata aatacctact ctattttcta ttatagtctc ttgctggcct
    28921 tttgtctgta agcaactgac cactagataa aacgttgtga aattcctttc tcataaattc
    28981 cataacttta gtatattata tttaagcact aaagtacaaa gaaagcaact gaaagcaatg
    29041 attttcacca ctgctttcgg atttattttg aattgttaaa tagccattcc tatccactat
    29101 tcttgaatag aaacacaaga tgcaatcttt attccagact cattttttca aatttattca
    29161 ccatccagca agagctcttt tggttgtttt ctaaggagat tgcttgaagc aagcgccata
    29221 acgagaacca ctagaaccaa ggcaaggaca aaaatgatga taaagtctga tgtctgaatg
    29281 gaaatgtcta ggctcgacaa ggtcttgcta aagccatcta cttctgcacc accaccaagg
    29341 ttagaggctt gagccgcctt actagcctgt ttggcaacac ctgaagtcac attggcaagg
    29401 acagtgtttc caattgcacg ggcagtgtaa ttagctagga agtaagcaga aactagagca
    29461 gggatagcaa tcaagataga ttcggtgatg aattgaccca agatacttgc ctgcttgagg
    29521 ccgatagaga ggagaattcc cacttccttg cgacgggcgt tgatccaaag gctgagcaag
    29581 agggcaagga ggagaactga gaagctcaag ctaccccaga agaggaggtt agccatcttg
    29641 tacataccag agatagattg ctcaagagct gggtagttag aggagctctt gacgagtgtg
    29701 tagctcttcc agttgatacc actgatgcca ttcaactctt tcataacatc atccaagttc
    29761 ttgtctgctg ttacaaagaa ggttgcgtcc ccataaatgg ctgtgtcttc tgtgtatcca
    29821 taaagttttg cagcagtgtg aatgtctgta atagctgtgt tttcgtaaag ttcttgtgag
    29881 taggttactg ctgacttatt atgaccatca aagagtccct tgattgtcac ttcaactgtt
    29941 tccttggctc ctttttcatt atctgcatcg tagatattag agtccagttt aaccttgtcc
    30001 cctactttcc agccgtgttt ggctgccaag tccttgtgca agaggatttt atccttgtcg
    30061 tcgttggtta agtgctctcc ttcgactagt ttataagaac cagagacaaa cttgtcttct
    30121 ttagaggagt cattgacacc tgtaatcatc aagctacttc caaaacgttt ggcacgatca
    30181 gcagtgagat tcttcttggt ttctggcgtt tcaatgaggt catatccagt caaatctccg
    30241 atagcgttga tacgtttgac ataagactcg atggccttgt tttcggtgat ttttttgatg
    30301 tcttcaccct tgatattccc agcaccacga ggcgttcctt ggttgacgcg acgattgatt
    30361 tgcatggaga agctattggt gatattttta aaggtctcct gagaagcctt ggcagtagct
    30421 cccttgattg acaagccgac caaactcaag ctcgccatga ggagaataat caggaagatg
    30481 acaatcgatt tgaaaaactt ccttgtaaca taggcaaatg cgttgtgtaa catagattcc
    30541 ctttctagat tttgttttaa tcattctatt aaaataagct caaattattt actagtattg
    30601 cgcgtttcag tcagtttctt atcctttaat tcaagtgtaa tatctgacgc ttgtgccact
    30661 tctttactgt gagttacgac aatcacacat ttacctgttt tctgggcaag tgatttgagt
    30721 agttcgacaa tatctccagc agttttagga tccagatttc ctgttggctc atcagctaga
    30781 ataactggag cttctgagac caaactgcga gcaatggcaa cacgttgctg ttgaccacct
    30841 gataactgga gaacattccg cttgatctgg ctttcatcca aaccaagctc aagaagtgta
    30901 tccttgcttg cctttttgtt gaccaagcgg atattttcca gcggagaaag ataatctatc
    30961 aagttataat tttgaaagac cagggaaata tggtgcatgc gatggtaaga atagcccttc
    31021 ttacgaatat cctctccttg aaaaaggata gaaccttcaa caggactatc tagaccagca
    31081 agtagggaca agagtgtgga ttttcctgct cctgactccc caataatact gtaaaatttt
    31141 ccgggttcaa aattataatc gatctgatat aggactgctt cagcagtatt cttataacgg
    31201 taggtaacat cttgtaattg taataaagtc atgatttctc cttcttaact aatagatgat
    31261 aaaatttctt tcggtgattt tctaaataaa aataggaaac aaagggctac agataagcaa
    31321 ctaagcagaa ctagaaaaac ataggattct gcaaaagata agatgctagt tgataaactg
    31381 cttgctttgg ctagtgtatc ttgtaagctt gcctgatctc cacttgctag tagagtttgg
    31441 agtaggtaag ttgtgattcc gtttcctgca acaaatgctg gaagcaaagc tccaagagat
    31501 accaaaacta cctctaaaca gaattgtagg aagatcgagc tcttgccttt tccaagtgca
    31561 agtaaaatcc ccacttcata gacccgttct ctcaaccaga gagacaaaac cagaattaag
    31621 gctccagctc ctgctatcaa catcccataa aggaagatgg tcaggaaggt ttggaaagtt
    31681 gcaactgagt ctttgatttg ttcaaaagcc ttgttttcct tttcgacttg gtagccttga
    31741 ttttccaagg ccaagttttc tacctgcttc atgagtccgt ccatttcctt aggattttct
    31801 acatagaagc gtgctgcact gacttgagct tcactattgc ccaaaagggt ttggctactt
    31861 tcatagtctg taaagacttg attttcactg aagtcagaag acaagcctgt gaatttctct
    31921 tgttttttac cagaaaagat gccgataatc tcaaactcta ctgtttgtcc ttttccagat
    31981 tcagactgac cagcatccaa gccaatcttg tcatgaagtg aaagaccgtt cttcttagcc
    32041 aattcttcgt ggataaggat tttcttggaa tccccttttt gaaggtgtcg cccttctttt
    32101 agattgaaag ccgaactggt aaaggttaca tccttggatg aatcctcaag agccgttaag
    32161 ctaaccaagt tattgtctgc agctgataaa tcatcacgct ccacgctctg ctcgccagtc
    32221 actgcttcct tgtcttttag ttttgcgacc gtctcaagtt caggagagac attttccagc
    32281 cccttaatct tgcttacaga tgctaggtct gacaacttga atgtctgacc attctctatc
    32341 ttcttaatag aaaaagatgt attgagtgat ttataaagat tgctttctac tgttttgttg
    32401 gacttcatca gagtcaaaca ggctgaaatt ccggccaata agaccaataa aatcagaaat
    32461 aaaataaaac ttctcagtcg ctttctgctg acataagccc aagatctttg gattggattc
    32521 atttgtcacc tccatatttg taagactatt ataaaaccca aatatgaaat gtttatgaaa
    32581 tacgaaaaaa aaatatcgag taggggataa tctctagccc ctctcacacc accgtacgtg
    32641 ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg taataatcca
    32701 aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt ttaagtaccg
    32761 acttctgagc tactatagta gattgaaact agaatagtac acctctactt ctaaaatatt
    32821 gttagaaatc gatttgactg tcctgattga ttcgtcctat tcttatttca ttttaatata
    32881 attgatagtg gtcgccccag ccagatacct tatctgctat ccatttagga acccctaact
    32941 taagcaatcc ccataatcgt ctcgatttct tcttccattg cttccagata atcactcgta
    33001 ggcgagtacg caagcgctca tctatgttag tgactatact tttcatattt ataattcatt
    33061 cctttcgttt cactcaaggc acaacacaga atgaaaaagt gttgtgatct ttattttgtt
    33121 ttataataat agtgagaaag cctatcacta ctacaaatca cggggaggtg aataagtgag
    33181 tggtacagcc actacctcgc atattttgtc acatcattta acggtacata ataagttgta
    33241 ccatctgaat aagttgctac aatatcattt gcatgctctc cttcaccttt agcaaaggtt
    33301 ggagctcctg ctggatgatt tttatttgcc tctttcaatt tttcaataat ggcatttttt
    33361 tctgtatctt ttatattatc aggatttttc actaaaattt tgtctggata tgtcggttta
    33421 gcagaaacaa tttttactgt tacttctttt ttattcgaag cacttgtcca gtttccagca
    33481 ttatctttag catttaattt tacagtaatt cctgaactag gaacttcagt agcaggttga
    33541 ttatcaacat tattcaactt taatttcaaa agagctgttg catcagacgt tttatcaatc
    33601 gttgtatata atgatgaatt gttattataa ccagtttctt catatttagc tgtttgtgag
    33661 ctacttgaga cagaactgaa attatgccca ctacctccct gattatcttc aatgcttacg
    33721 tctaaatgaa cttccccact attatttggc ttagcaacaa ctgttatagt aaaataacat
    33781 aaaatttgca taaatagatt agggaaatca aagcaacttc taggaatgtt ttagcagtca
    33841 cagtgtactt tcccagcatc aagccactat aactctgcac ataaaaatgg agaagatggc
    33901 catcctcttc tccaaatatt aacttcttta caaaccaact atagttgaca aagaacctaa
    33961 aatcaattga taacacaagg tcaggtcggt caactctttc aactgaagcc ctgtcaactc
    34021 ttcccattta tcaatcttgt attggagaga attgcggtgc agatagagtt gctgagctgt
    34081 tttagtgaga acagcactat tttcccaaag agagagaatg atttcctgaa tctgatcttg
    34141 atccaaaatc atctggtgta gacattcctt gattggcttc aagtccacga gtctttctcc
    34201 catactccaa agatagagct gagaaaaagt atgaacacct tggtgaccct gacgccacca
    34261 tgtcttgaac aaatcccgct cagctttgat taagtctgat agggcttgat gtcccgtctg
    34321 agaccaaacc tgacccaaca tgatagaaag acgaagtcca aagtcatact caaccgcttc
    34381 aatcgtatca cttaaaatat ctcttacaga agtgtatttg tcttgttgaa gcacgaaaac
    34441 ataatcctga gatccgacct gtagcactgt ctgacaattc ggaaaaagag tccgcatcat
    34501 atctagccaa gaagccagat tttcctgctg aaaataagaa agatggcaat aaaccaactg
    34561 aatcttttta aaaacttgcg gtgcctgtcc cttgccttca accagatagg aataccaagg
    34621 gtttagcgaa cgagcctgct cctgctgggt caaaagggca accaactgct tttcacgctc
    34681 gctgagccca gcttcctcca gcaaaatcca ctgctgagaa gctaaaggga gcgtgagata
    34741 gccctctttc tctactggtt ggtctgaaat ccgagcctca ggaaaccagt cttgtagttc
    34801 tttttccctc atgttctagc cctccacttt ttggatgcac catgaaacca aactctcaag
    34861 acgttccaga ttctcagtca tatggagata gcccataacc gcttcaaatc ccgtggacat
    34921 acgataagtc acgacatctg catttttagc ctttgtgtgg ctattggtat tgcggccacg
    34981 tttgtagatt tcttcttctt tttccgttag gacctgctcc tccaacatga gagcaatcag
    35041 gcgagcctga gccttggctg acacatactt ggttgcttct tgatggagtt tattgggttt
    35101 ggtcatacct ttgaggatga ggtgacggcg aatatacata gaatacaccg catccccctc
    35161 aaaggctagc gcaatcccgt taatgagatt gacatcaatc acgtgtccac ctcactccat
    35221 ccttggtatc aaggagctta attccttgag taaccaattg gtcacggatt tggtctgctg
    35281 tctcaaagtc tcgattggca cgcgcctctt ggcgtttttg aatcaagtct tcaatctctg
    35341 catccaaaac ttcctcaaca aagacaattc caaaaatttc taacatatct gcaagagctt
    35401 gcttgacact tgcatcatag ttccctgagt tgatccattt ggccatttca aagacaactg
    35461 tgataccgtt ggcagcatta aaatcttcat ccatagctgc tacaaactta tctttaaagt
    35521 tttgtaactc ttgggcatcc acgtttcctg taaatggttg ttcgtaagta ttcttcagat
    35581 acttgagatt ggtctcggca tcgcgaactg ccttttccgt gaagttgata ggcttacggt
    35641 agtgctgggt cgcaaagaag aaacgaagta cttgcccatc aagagtttta agggcatcgt
    35701 gtaccgtaat gaagttaccc aaggacttag acattttgac attgtcgata ttgacaaagc
    35761 cattgtgcat ccagtagtta gcaaaagcct tgcctgtttt agcttcagac tgggcaattt
    35821 cattggtgtg gtgtggaaac tctaggtcag ctccaccacc gtggatatca atggtatcac
    35881 ctaaaatctc tgtcgacatg actgaacact caatatgcca acccggacgt ccaggtcccc
    35941 aaggactatc ccaagaaatc tcacctggtt tggaagattt ccatagagca aagtctacag
    36001 gattttcctt acgagccgtt tcttcatcgg tacgacctga agcacctagc tccaaatctt
    36061 ccaaggtttt attagccaat ttagcatagt tgtgggattt ttctacacgg aaatagacat
    36121 ccccttgact ctcataggca aagtctttct cgatcaagtc ttccacaaaa cggatgatgt
    36181 ctgccataaa ctccactaca cgcggatggc gagtcgcagg tttcacgccc aaggccgcca
    36241 catcctcacg aaaggcagcg atgtacttat ccgcaacctc ctgaggcgtg ataccttctt
    36301 ccctggcacg gttgataatc ttatcatcca catctgtaaa attggaaata taggcaacct
    36361 tatacccacg gtactcaaaa tagcgacgaa tcgtatcaaa agctaccgtc gaacgggcgt
    36421 ttcccacgtg gatatagttg tacaccgttg gcccacaaac atacatcttg atcttgccgt
    36481 cctcaatcgg gacaaattcg cgcaaatcac gagacatggt gtcatagatt ttaatcataa
    36541 atcataatca agaaagctga aatccaagaa caattagttt catcactaaa agttcaagta
    36601 aatttcagtc cgaatatctc tacacttcgg aatcccttgc tcctttctca ttcagataaa
    36661 ccacctgagt ctgtttgaca aagccaattt tttcatacaa acgtttggca cctacattgc
    36721 tatcttccac tgcaatctga aattccttgt cattttgctc aattagttgg ttgacgaggg
    36781 attttgctaa gtagcttcca tagcctttcc cacgttcagg ttccgatatt gctaaaccgt
    36841 agaagtaatt cgtattagtc gataaatcta ccgtgcaagt cccaataacc tgaccgtctt
    36901 ttaacaaaat atataagcga ctttctggat ccttcagagc ttcagcgaca tatctatcca
    36961 caacttctct cgattcatgt ccctctgaaa atgcctgaaa ttttaattga ctaatttgat
    37021 cctgatacaa actatctgct aacaaaattt caagatggga aacatttgct aacggataag
    37081 gtcttctatc cttacctaac caagtttctg tctcttcatc ctcgattagt ccccagttac
    37141 tggcaaagtc aggatgattc tctaaaaaaa tacgttctgt ctgaaaagtg actgaccgaa
    37201 tggggaaaga agctgtttct ctctcaaaac tagtaaacaa tgcacgcgca atcccctgac
    37261 ggcgatgacc tggatgaacc agtatcgtca cttctacatc ttggtcatct gcatagacag
    37321 ttaataaacc aacaagtttg cctttttcat aataaaggaa aaaggcgggc atgtttgggt
    37381 caaaattaag catgttagag agatagggat cgcgataggt accgtcatag ttttggcaac
    37441 agttaattac ttttttcgcc tcagatagct cttcttggct taacttgttt cttgcttgaa
    37501 tcatataggt atcctctaca aaccagacga tctgtgactg gcatctttag cctgctcgag
    37561 tttattgaca taatactccc gtttttcttc gacttcgtga atgacaggct catctttctt
    37621 accatgaaga cggacaatct tggccggaat accgacaacc gtcacatcac taggtacatc
    37681 tgctacgaca actgctgcag caccgacctt ggcattttca ccaatttcca caggcccgat
    37741 aacttgggca tgggctgata tgagggctcc ctttcgtaca gtcggatggc gtttgccaca
    37801 gtctttccct gttcccccga gagtcactcc gtgatagaga agaacgcctt tttcaacaat
    37861 cgctgtctct ccaatcacca gaccagaacc atggtcaata aagacacctg aatcaatctg
    37921 ggctcctgga tgaatctcaa tctgagtcca aaagcgccaa aactgactgt gcatacgagc
    37981 taagagtttg aagtcgtact tccagagaaa atgcgagaga cggtgggccg ccaaggcctt
    38041 gacacctgga taagtcagca aaacctccaa agtggtgcgg gccgctggat cattttcttt
    38101 tacgatatca atggtttcgc gccaccaccc catacatttc tccttttctt actctgaatc
    38161 ttttggtgtt tctgtaaatt ctttcttagg tttgtgatcc ttgtgatgac gtgggcggtg
    38221 agggcgctca gacttttcac ctttttcatc atgctcaggt tttggcggac gaggtagaag
    38281 agccttcata gaggcatcga tacggccttt ttcatcaatc ttgataacct taacatcaac
    38341 ttcatccccg atttctacca aatcctctac acgattggta cgagtccaag ccatctcaga
    38401 gatatgaaca agggcatctg tcttatcaaa gaggttaaca aaggcaccaa atttctcgat
    38461 acgaacgact ttagcacggt aagcttcatc cactttggct tcacgaacca aaccagcaat
    38521 aatttctttg gcacggttaa tagcatcttg gtcactagag tagatagaca catttccttc
    38581 ttcgtctata tcaatcttaa cacctgtttc agcgataatc ttgtcgatgg tttctccacc
    38641 cttaccgatg acaatcttaa tcttgtccac atcaatcttg atcgtatcaa ttttcggagc
    38701 agttggagcc aattctagac gaacttctgg aatggttgct tcaatgacat caaggatttc
    38761 aaaacgcgct ttcttggctt gagcaagagc ctccgtcaag atttctgcag taatcccttg
    38821 aatcttgata tccatttgaa gggctgtaat cccatcacga gtacctgcaa ccttgaagtc
    38881 catatctcca aagtgatctt ccaaaccttg gatatctgtc aatactgtgt agttatttcc
    38941 atctgagata agtcccatag caataccagc tactggcgcc ttgattggca caccaccagc
    39001 cataagggca agagttcccg cacagataga agcttgagat gaagaaccgt ttgattccaa
    39061 aacttctgct actagacgga tagcgtatgg gaattcttcc aagcttggca agacttgagc
    39121 aagagcacgc tcaccaaggg caccgtgacc gatttcacga cgacctggcg caccgtaacg
    39181 acctgtttcc cctacagaat attgagggaa gttatagtgg tgcataaagc gtttcttgta
    39241 ctctggatcc aaaccatcaa tgatttgagt ttctcccatc ggagccaagg tcaagactga
    39301 aagagcttga gtttgcccac gagtaaagag acctgaacca tgtacacgag gaaggaagtc
    39361 aacaaccgca tccaaaggac ggatttcatc gaccttacga ccatcaggac gcaccttgtc
    39421 ttctgtaatt aaacgtcgca cttctgcgtg ttccatttgt tccaagattt cagccacatc
    39481 acgcataata cggtcaaatt cttcgtggtc cgcatatttt tcttcgtaaa cggcagtcac
    39541 ttggtctttc actgcttgag ttgcagcttc acgggccaat ttctcttcta cttgaactgc
    39601 cttttggagg tcactgttgt aggctgcaat gatttcagct tgcaattcag catccacgtg
    39661 aagcaattcc acttctgctt tttctttacc gacagcagca acgatttctt cttggaaggc
    39721 aatcaattct ttgacagctt cgtgcccttt aaggagcgct tccaacatga tttcttctga
    39781 caattctttg gcaccagact ctaccatgtt gatagcgtgc ttggttccag ctactgtcaa
    39841 ttcaagaaga gattgctctg cttgttcttg acttgggttg atgatgattt ggccatctac
    39901 atatcccact tgtaccccag caattggtcc gtcaaatgga atatctgaaa tagacagtgc
    39961 caaagatgaa ccaaacatag cagccattgg tgcagatgca ttttcatcat aagaaagcac
    40021 tgtattgatg acttggactt cattacggaa accttccgca aacataggac gaatcggacg
    40081 gtcaatcaaa cgcgctgtca aggtcgcatc tgttgaagga cgtccttcac gtttcataaa
    40141 gccaccagga aacttcccag ccgcatacat tttttcttcg tagttgactt ggagtgggaa
    40201 gaaatcccca gttgccattt tcttagacat aacggcagca gtcaagacag ttgactcacc
    40261 gtaacgtacg acaacagatc catttgcttg cttagcaacc tgaccagtct ctacaattaa
    40321 ctcacgaccc gcaaaagtcg tttgaaacac ttgttttgcc attttaatcc cctttggatt
    40381 gatgaaatta tacgccttgc ctacaaagat caagatacca aggacgtcaa aagcaaagta
    40441 aaaataggaa actgacgaag tcttcgatga agacaagaca gtttatcttt tttacacagc
    40501 ttttcggccg tgttcaatta cacaagatat tttggacggt tcggcttgcc gaacatttct
    40561 gtagaaaaat aggaaggtga cgtcgcactc gacgagtgct aggaagctta tcttttttcc
    40621 taagaaatga gaccaaaatt caattactca agatactaag ccgtcaagca actcaaagga
    40681 aaataggaaa tcgaacgacg gagcgactgc tcctagggag atttatcttt ttccacagag
    40741 ttgtaggcga gttcaatttt caagatataa atcattagaa aggtttaata ctaaagtatc
    40801 taaagctttc acgctaatcg ctatcgggcg attagctaaa tgctttacta actctctcgt
    40861 caaataacat cgatttgact cactcgtgtc gttaaatctt acagtttaaa tgcattgtat
    40921 tatttaatac cttcatcttt gtatcaagta cgtacagaat ctattttatc atatttttct
    40981 taaaaagtga ggtctttacc attaaaaagg aaccattccc ctcacctgag aagaatggtt
    41041 tgcttttatt atcctagaga ctggtgatta aacaaggcat gggttgcttg atggatgtat
    41101 tttgctgtat cagcattatt catcgtatag agatgcacac cggcaacatc ctgagttacc
    41161 aagtccacga tttggtccac tgcataggca agtcctgctg ctctgagcga ctcagggtca
    41221 tgctcatact tgtctaagat ggctttaaat ttgcgtggaa gatggatatt ctcacaagtc
    41281 ttcaagagtc ggagagcctg atttcgattc agaattggca taattcctgc atgaatggga
    41341 acatcaatcc cagccaagat acacttgtcc tgaaaatcat agaagcgctc attgtcaaag
    41401 aagagctgag ttacgaggct cgaacagcct gcatccactt tcttcttaag attttgaata
    41461 tctgaaatct gatttggcga atctggatgc ccttctggat agcaagctcc aataatatca
    41521 aagtgagggg cttgttcctt gataaactca atcaagtcgg ttgcatagcg gaaatccttt
    41581 tgtggttcta cgtctggaat aatatcccca cgaagagcca agattttctg aaccccaact
    41641 ttgtccaagt cagcaatagt ttcagcaacc ttgtccttag ttagataaat agctggcaag
    41701 tgggcaatgg tcggaatcgc caagtcattt tggataaagt cagccaaacg aaccgtcgtt
    41761 tccttgatat taaatttatt attgctggca gttacactga taaaatgggg agccaactcc
    41821 tgcatatcct gcaaggctga aatactgtta ccattaccca cggctgggtt tggagggaac
    41881 acttcaaatg agagtgacgg tgtttggcgt gacatatgta ataacctttt ctagttgatt
    41941 tctttttgaa caaccactgt atggagagaa atccaatctt acaatttctc acgcgcagct
    42001 ttagctgctt caacaaggcg gatcaagctt tcttttgttt ctgggatacc acgtgttttc
    42061 aaaccacagt cagggttgat ccaaactttc ttgcttggca ctttagcaag gatggcttcg
    42121 attgtgttgt cgatttcgcc ttcatttggt acacgaggtg agtggatatc gtaaacccca
    42181 ggtcccactt ctgtttggaa gtttttcgct ttgagttcgt ccaagatttc aaggtttgaa
    42241 cggctagctt caaaggaaat aacgtctgca tccatgttat cgatagctgg gatgatatct
    42301 gtaaattctg agtaacacat gtgagtgtgg atttgtgtgt ctggcgctac tgttgagtgt
    42361 accaagcgga aggcaggaat agcccagtca aggtagtctt cgtaccagtc gctacggcgg
    42421 agtggcaatt tttcacgaag agcagcctcg tcgatttgga tgattttcac accagcagct
    42481 tcaaggtcaa gtacttcatc cttgatagca agggcgattt ggagagttga atccttgata
    42541 gagatgtctt cacgtgggaa tgaccagtta aggatggtaa caggtccagt caacatacct
    42601 ttaacaggtt tgtttgtacg actttgtgca tagctagacc atttaacagt gatagggtta
    42661 agacgagtga catcacccca gatgattggt ggttttaccc cacgcatacc gtatgattgt
    42721 acccatccat ttttagagaa gaggtatcct gacaagtttt gaccgaagta ctcaaccatg
    42781 tcattacgct caaattcacc gtgaacaagg acatcaaagt caatatcttc ttgccacttg
    42841 atccattcgt caatcgtttc agcaaggaaa gcgtcgtact ctttttgaga caattcacct
    42901 ttacggtaag ccaaacgttt ggcacgaact tcttttgttt gagggaatga accaatcgtt
    42961 gttgttggaa gagctggaag tttgaaagct tcttcttgga tagcttcacg ttctgcaaag
    43021 gctggcaaac gagtgtagtc tgcgtctgtc aagccagcga tacgcgcacg aagttcagca
    43081 ttttcaccaa cacgctcagt cgcaaagagt tctttgttgg ctgcaagagc ttctgaacct
    43141 tgaccattgc ggatagcatc caagtcacgg atttcatcca atttttcaac tgcaaaggca
    43201 aagtggttca agagtgctgg ttcaaattct tcattagcag ttgtaaatgg cacatgaaga
    43261 agtgagcaag agcttgtcaa aacgatgttt tcagctggga tttgctcaag aacagccaag
    43321 ctcttttcgt agttgttgcg ccagatgttt ttaccattga caatacctgc atagagagtc
    43381 ttgtcagctg ggaagccacc tttaacgagt tcaagagttt tcttaccttc aacaaagtca
    43441 agaccgatag catctactgg caagtttaca aggtcagcgt atacgtcacg aacatcaccg
    43501 aaataagttt gaaacaagac ttcaagacct tttttgtcag ccaagagttt gttgtaaagg
    43561 ttcaagaaga gagctttttc ttcagctgtc aagtctttta caagagccgc ttcatccaat
    43621 tggatgcgag tcgcaccaag gtcagccaat ttagcaaaaa cttcttggta agcagccaca
    43681 aagctatcta cgaagtcgtc tgctttcacg ccttcttcaa agtctgacaa ttgaaggaaa
    43741 gtgaatggac ctacaagaac aggacgagtg tccaatccaa gttcttttgc ttcttggaac
    43801 tcatcgaaaa tcttgtgacc agccaatttt acttgagtgt ctttttcaaa tttaggaacg
    43861 atgtagtggt agttagtgtt gaaccatttc ttcattggaa gggcgcgaac gtcccctttt
    43921 tctccctggt aaccacgtcc caaagcgaag tagcgctcaa ggtcagacaa gtccaagttt
    43981 tgaacggatg caggcaccac gttgaaaagg aaagccgcat ctaggaagtt atcatagtga
    44041 gaaaagtcat ttgatggaat ttcagtgatg cctttttctt tgacaatgtt ccagtgttta
    44101 gcacgcaagt cttttgctgc tgctaaaagt tcttcttctg agatttcttt tctaaagtat
    44161 ttttcagttg taaattttaa ttcacggaat tcgcccaaac gagggaaacc gatgattgta
    44221 gttgacatga tgtgtcctcc aaaatttgtt gttgaaacta tcttaacaga aaagaaagcg
    44281 tctgtataat tgtaaaaaat tagggtttga tatagtttga aactatatat ctgtttcgga
    44341 caaaagaaaa agacttgaag caaacgtctc aaatcctttg tatagcttgt tttatagctt
    44401 tatttcagtt agacggttca aacgcgttat tagtaattct tataagtgac tatggcttgt
    44461 tattagaaaa gactataact gattctagtc aactttttcc ctgttcaagt cggacgactg
    44521 ctagtgtctt tcctaaactg gctaggactt ttaagactgt atccaactga ggactagtct
    44581 ttcctgtctc catcctagct atgacaggct ggcttattcc actgacttct tccagctttt
    44641 tctgactgat tccttgttca tacctagcct caatcaactc gctcatgata gccactcgca
    44701 tatcactttc aaggatttcc tccttgctaa agagctcaga tggacatcct tccaattact
    44761 cccaatagca ctattcttca tcacttaacc ctctttcttt tacgtctatg tatttttgaa
    44821 aaaatgagcg aattatgatt cgatagactg accagcaggt ttaaaattgg gactagcttg
    44881 tttcttaagc gcttttcctt ttctaggata aagcaaatcc tgtttgctta accccaattt
    44941 tccatgatga atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac
    45001 catcatttca ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt
    45061 ggtcaagctt gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcata
    45121 gtcggcagaa taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg
    45181 cttgatttca gtgtggatag tttgaggagc ttttccaagt agagaggcaa tttctctatt
    45241 tgatttccct tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt
    45301 ggcttttgta gtataattgt cttgcatctc tgtgcctttt aatcatttca atcttaaatt
    45361 ggactttttt tacttgggtt gtacttaatc tatgaggaag acaagaaaaa gaatatcaat
    45421 caagtaaagt cacaaagtca cattagctcc gagcaaccat tgcaaattga ggtactcaca
    45481 caatgattaa aacatttctc tctgcccttt cggtcattct cttttctatc cctatcataa
    45541 cttattcttt tttcccatct tctaatctta acatttggct atctacccaa cctatcttgg
    45601 cacagattta tgccttcccc ttagctactg caactatggc tgctatttta agtttcttat
    45661 tttttttcct atctttttac aagaaaaata aacaaatacg gttttactct ggcattttgc
    45721 tcttactatc gctcatatta ctattattcg gaacagataa aaccctttct tctgcatcaa
    45781 ataagactaa aaccttaaaa ttagtaactt ggaacgtcgc taatcaaata gaagcacaac
    45841 atattgagcg aatttttagc cattttgacg ccgatatggc tatattccct gaactagcta
    45901 ccaatatcag aggtgagcaa gaaaaccaga gaatcaaact attgtttcat caagttggac
    45961 tttctatggc caactatgat attttcactt ctccacctac caatagtgga atagctcctg
    46021 tgactgtgat tgtcaagaaa agttatggtt tctatacaga agctaaaact tttcatacaa
    46081 cacggttcgg gacaattgta ttacattcga gaaaacaaaa tataccagat atcattgcct
    46141 tgcatactgc tcctcctctg ccaggtttaa tggaaatctg gaagcaagac ttaaacatca
    46201 ttcataatca attggcttca aaatatccaa aggctattat tgcaggtgat tttaatgcaa
    46261 ctatgcgtca tggagcactt gcaaaaataa gctctcatag ggacgcatta aatgtactgc
    46321 caccttttga aagaggaact tggaatagcc aaagtccaaa actttttaat gcaacaatag
    46381 atcatatttt attgcctaaa aaccactact atgttaaaga tttagacatt gtaagttttc
    46441 aaaactctga tcatagatgt atttttacag aaatcacatt ttaattattt tatataaaat
    46501 cacccctcta gtgttcataa actagagggg gaatttgtat catactatcg tttaacgcac
    46561 ttctgcattc actttttctt cgagcgatgc ttggattttt tccatatagc gtgcgacttc
    46621 ttcgtccgtt aagctatctt ctggattttg gaaggtcaag ctataagcca ttgacttcat
    46681 accaagtccc aatttctcac ctgagaagac gtcaaagagt ttgatatctg tcaaacgttt
    46741 cacgccggca gcttggatag catctacaac ttcttgatga gtcacttctg ccttgaggag
    46801 aagggcaacg tcacggctga ctgccgggaa tttggtgatt tctacaaatg gagtcgctgg
    46861 ctgaagcgca gcttcgatag ctgaaaggtt aagctcagct acatacgttt ctggaatatc
    46921 gtaagccttg gcagtgactg gatgcacttg gccaaggaaa ccaagaactt ggtcaccgag
    46981 tgaaatcacg gctgtacgac ctggatgaag gctagcgatt tcagatgttg ctgtataggt
    47041 tacttggagt cccaaacgag taaatagggc ttcaaggatt cccttagcat agaagaaatc
    47101 aactggaact gctgctgttt ggaaatcttt ttcagcaacc aagcctgtca aggcaaaggc
    47161 aaagctgttg atctcatttg gaagttcttc ttttggatta cctgtttgtt caaagacttt
    47221 tccaatctca taaagggcaa agtttttatt cttacgagcc acgttgtagg caacggtatc
    47281 aaggatccct gaaatcatat tttgacggag gactgaacga tccacagtca ttggccacat
    47341 gagttcagta aggttactcg gttgagctgt gaactcaact gctttttcag gagttgtcag
    47401 agcataggtg atgatttctg tcaaacctac tccttcagca atggtacgaa cttgacggcg
    47461 gagtttttgt gtcacagtca attcaccagc tgtaccatcg tcttttggaa ggctggttgg
    47521 caagcggtca tatccataga tacgagcgat ttcttcaaag agatcagctt cgattgtgat
    47581 atcccaacga cgacgtggta cgctgactgt aaagctgtct gcatttccag aaagaccaaa
    47641 gccaagacga cggaagacgt cttctacatc agcataagac agctcagttc cgaggacacg
    47701 gttaacatca gcaagggttg aagaaacttc cacatcagag gtatcaagct cacccgctga
    47761 aacgataccc ttacgcaccg tcgcgcctgc aagctctgca atcatgctag ctgccgcatc
    47821 aagggcttca ttaactgttg ccacattaat tcctttttca aagcgagaag atgactcaga
    47881 acgaaggttc aggcgaccac ttgtcttacg gatagatttg ccattaaaaa tagcagcttc
    47941 aaggataaca cgactagatt tttcagaaat ttctgtagcc tgaccaccca taacaccggc
    48001 aagggctact ggtttgtcag caactgtaat cacgaggtct gtctcagcca agtctcgttc
    48061 ttcaccgtcc agggtcacta atttttcacc atcacgcgct tcacgcacac ggatgtcagt
    48121 cccttcaaag ttatccaagt caaaggcatg cattggttga ccaaaataga gcaggatgta
    48181 gttggtcacg tccactacgt tattgatggg acggatgcct tcgttcatga gaaggttttg
    48241 caaccattgt ggacttggtg cgatggtcac attgtccaag atacgagctg catagtaagg
    48301 cgccttgtct gtcccaatgc tgacagaaag ggcatctgcc gcagattcat tagtttctgt
    48361 tagagtaaat tctttaaagt tgactgcctt gtcatagatg gctgccactt cgtgagccac
    48421 tccacacata gaaagggcat ctgcacggtt tggtgtgatg gaaagttcga tgatttcatc
    48481 atccaagtct aggtaagaaa agacttcctc acctggcacg gcattttctg gcaagatttg
    48541 gatgccatct gcgaattcct taggcacaac tgagtcagaa attcccaatt caccaagtga
    48601 acagatcatt ccaagtgact ccaaaccacg gatttttcct tttttgattt tgtagttatc
    48661 agcaatacga gctcctggaa gagccaccat gaccttgatc ccagcacgca catttggggc
    48721 accacaaacg atctgacggg cttcttcttc gccaacgtta acctgacaaa catggaggtg
    48781 agtctctggc acatcttcgc aagacaagac ctcaccgaca acaatttttg agagatcagc
    48841 agctggtgat tcgacactct ctacctcgat ccctgtggtt gacatttttt cagccaactc
    48901 ctgtgatggc acatcaatgt ccaccaattc ttttaaccat ttataagata caagcataat
    48961 ttagttctcc agaatgacca ttgccacact ggttcttttc ctttcctatc atttcaatag
    49021 aagaattctc ttcttacctt aatttctttc tcagtaacca atccgtatct actttttgac
    49081 caaccataaa atgatgttgg ctaaattttt caaaaccata tcggttataa aacgcttgag
    49141 cttttgtatt atgctcccaa acacctagcc aagcccaaga aaaactattt tttgtagcaa
    49201 gttcaagtgc gaattcaaac agttgcttac ctagtccaaa tccttggaat ttttgtagca
    49261 catagaggcg ttgaatttca aaagcgtcct ctaattctct ctcagtttga gcacttcccc
    49321 agttgacttt gagaaaacca gctatctcct cctcatgcat aatgaaatag gtttcagagt
    49381 caggatttcc caactcagtt gacaaagttt tcagactata agcctcttca aagtattcct
    49441 gtaactgctc ttccgtatta tcatacgcaa aggtttcacg aaaggcttgt ttggcaattt
    49501 tagccaacac ctcaacatct gccatttcta cttttctaat cattatttaa actgttctga
    49561 gaagcggaca tctccttggt agaatccacg gatatcgttg attccataac ggagcatagc
    49621 tacacgctct tgtccaagac caaaggcaaa gccagagtat acagtcgcat cgataccact
    49681 catttcaagg acacgtgggt gaaccatacc ggcccccata atttcgatcc aacctgtttt
    49741 cttacataca ttacagcctt ctccaccaca cttgaagcaa gaaacatcca cctcaacaga
    49801 tggctctgtg aatgggaagt aagatggacg caaacgaatt tgacgctctt caccaaacat
    49861 tttttggaca atcaactgaa gcgttccttg aagatcagcc atagagatat ttttcccaac
    49921 taccaagcct tcgatttggt ggaattggtg actgtgggtc gcatcgtccg tatcgcgacg
    49981 gaagacacgc cctggcgaga tcatcttcaa aggaccttta gaaaaatcat gggcatccat
    50041 agcacgcgcc tgaactggag acgtgtgggt acggagcaag atttcttcag tgatatagaa
    50101 agtatcctgc atatcacgag ctgggtggtc ttttggaagg ttcatacgtt caaagttata
    50161 gtagtcttgc tccacttcaa aaccatccac gacttgataa cccataccga tgaagatatc
    50221 ttcgatttct tcactggttt gtgtcaaaac gtgacggtga ccagtcgcaa ctggacgacc
    50281 tggaagcgtc acatcgatac tctcgctagc cagttgagcc gcgactttct tttcttccaa
    50341 gagcttagct gtttcttcaa aagcagctgt caagacatca cgagcttcat tgacgtgttt
    50401 cccgatgatt ggacgcatct cagcagaaac atctttcatc cctttgagga tttcagtgag
    50461 cgaacccttt ttaccaagga cagagacacg caaatcttgc atctcttttt catttccagc
    50521 agtaatctgc ttcaagctag tcagcgtttc ttcgcgaagc gcttttaatt gttcttcaat
    50581 agttgacata tttcctccat cagtctctcg tagataaaaa gaaaaccaca tgccaaaaac
    50641 tccactcgga gcgttgacac gcggtaccat ccgttttcat ctgacaagtc agaccttcat
    50701 ttctaaatcc atgcgcaagt gaattcaccc agctttcata tagagaactt gcagtcacgg
    50761 ctctcctccc tgatatactt cccttgggct actagtcttt cagattccta ttcaattact
    50821 acttagttta tcagattttt accattcttg caagacctat cttacttctg cttgttagct
    50881 tattcttatc taactttata gc
//
LOCUS       DBEJJE010000008        50702 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEJJE010000008 DBEJJE010000000
VERSION     DBEJJE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.08"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(113..1279)
                     /gene="recA"
                     /locus_tag="ACL3F5_000477"
     CDS             complement(113..1279)
                     /gene="recA"
                     /locus_tag="ACL3F5_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0514332.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEGAVNEEVTLDLGDELEIEIEE"
     gene            complement(1334..2590)
                     /locus_tag="ACL3F5_000478"
     CDS             complement(1334..2590)
                     /locus_tag="ACL3F5_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0514333.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2674..3690)
                     /locus_tag="ACL3F5_000479"
     CDS             complement(2674..3690)
                     /locus_tag="ACL3F5_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0514334.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3698..4216)
                     /locus_tag="ACL3F5_000480"
     CDS             complement(3698..4216)
                     /locus_tag="ACL3F5_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0514335.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4206..4649)
                     /gene="tsaE"
                     /locus_tag="ACL3F5_000481"
     CDS             complement(4206..4649)
                     /gene="tsaE"
                     /locus_tag="ACL3F5_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0514336.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4735..5355)
                     /locus_tag="ACL3F5_000482"
     CDS             complement(4735..5355)
                     /locus_tag="ACL3F5_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514337.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5738..6601)
                     /locus_tag="ACL3F5_000483"
     CDS             complement(5738..6601)
                     /locus_tag="ACL3F5_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0514338.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            6790..6960
                     /locus_tag="ACL3F5_000484"
     CDS             6790..6960
                     /locus_tag="ACL3F5_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR0514339.1"
                     /translation="MKKNRGIQKLAILVLLGVFMLSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            7105..9120
                     /locus_tag="ACL3F5_000485"
     CDS             7105..9120
                     /locus_tag="ACL3F5_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0514340.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEVGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9122..9754
                     /locus_tag="ACL3F5_000486"
     CDS             9122..9754
                     /locus_tag="ACL3F5_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514341.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            9895..10173
                     /locus_tag="ACL3F5_000487"
     CDS             9895..10173
                     /locus_tag="ACL3F5_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HGR0514342.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(10683..11096)
                     /gene="ndk"
                     /locus_tag="ACL3F5_000488"
     CDS             complement(10683..11096)
                     /gene="ndk"
                     /locus_tag="ACL3F5_000488"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0514343.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11207..14884)
                     /gene="rpoC"
                     /locus_tag="ACL3F5_000489"
     CDS             complement(11207..14884)
                     /gene="rpoC"
                     /locus_tag="ACL3F5_000489"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0514344.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPTVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(14917..18528)
                     /gene="rpoB"
                     /locus_tag="ACL3F5_000490"
     CDS             complement(14917..18528)
                     /gene="rpoB"
                     /locus_tag="ACL3F5_000490"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0514345.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            18944..19014
                     /locus_tag="ACL3F5_000491"
     tRNA            18944..19014
                     /locus_tag="ACL3F5_000491"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18976..18978,aa:Cys,seq:gca)
     gene            complement(19212..20543)
                     /locus_tag="ACL3F5_000492"
     CDS             complement(19212..20543)
                     /locus_tag="ACL3F5_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0514346.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(20834..21658)
                     /gene="endA"
                     /locus_tag="ACL3F5_000493"
     CDS             complement(20834..21658)
                     /gene="endA"
                     /locus_tag="ACL3F5_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0514347.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSLKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(21697..21885)
                     /locus_tag="ACL3F5_000494"
     CDS             complement(21697..21885)
                     /locus_tag="ACL3F5_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0514348.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(21878..23161)
                     /gene="murA"
                     /locus_tag="ACL3F5_000495"
     CDS             complement(21878..23161)
                     /gene="murA"
                     /locus_tag="ACL3F5_000495"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0514349.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23185..23415)
                     /locus_tag="ACL3F5_000496"
     CDS             complement(23185..23415)
                     /locus_tag="ACL3F5_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0514350.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(23473..24510)
                     /locus_tag="ACL3F5_000497"
     CDS             complement(23473..24510)
                     /locus_tag="ACL3F5_000497"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0514351.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(24494..24982)
                     /gene="coaD"
                     /locus_tag="ACL3F5_000498"
     CDS             complement(24494..24982)
                     /gene="coaD"
                     /locus_tag="ACL3F5_000498"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0514352.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(24972..25511)
                     /gene="rsmD"
                     /locus_tag="ACL3F5_000499"
     CDS             complement(24972..25511)
                     /gene="rsmD"
                     /locus_tag="ACL3F5_000499"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0514353.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(25576..26568)
                     /gene="asnA"
                     /locus_tag="ACL3F5_000500"
     CDS             complement(25576..26568)
                     /gene="asnA"
                     /locus_tag="ACL3F5_000500"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0514354.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(26680..27363)
                     /locus_tag="ACL3F5_000501"
     CDS             complement(26680..27363)
                     /locus_tag="ACL3F5_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGR0514355.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(27419..28159)
                     /locus_tag="ACL3F5_000502"
     CDS             complement(27419..28159)
                     /locus_tag="ACL3F5_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0514356.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28193..28471
                     /locus_tag="ACL3F5_000503"
     CDS             28193..28471
                     /locus_tag="ACL3F5_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0514357.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            28549..29475
                     /gene="yidC"
                     /locus_tag="ACL3F5_000504"
     CDS             28549..29475
                     /gene="yidC"
                     /locus_tag="ACL3F5_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0514358.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(29550..30344)
                     /gene="pflA"
                     /locus_tag="ACL3F5_000505"
     CDS             complement(29550..30344)
                     /gene="pflA"
                     /locus_tag="ACL3F5_000505"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0514359.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(30470..31720)
                     /locus_tag="ACL3F5_000506"
     CDS             complement(30470..31720)
                     /locus_tag="ACL3F5_000506"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0514360.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(31787..32614)
                     /gene="purR"
                     /locus_tag="ACL3F5_000507"
     CDS             complement(31787..32614)
                     /gene="purR"
                     /locus_tag="ACL3F5_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0514361.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(32881..33822)
                     /locus_tag="ACL3F5_000508"
     CDS             complement(32881..33822)
                     /locus_tag="ACL3F5_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0514362.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(33812..35068)
                     /gene="rmuC"
                     /locus_tag="ACL3F5_000509"
     CDS             complement(33812..35068)
                     /gene="rmuC"
                     /locus_tag="ACL3F5_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0514363.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35070..35732)
                     /locus_tag="ACL3F5_000510"
     CDS             complement(35070..35732)
                     /locus_tag="ACL3F5_000510"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0514364.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(35695..36351)
                     /gene="rpe"
                     /locus_tag="ACL3F5_000511"
     CDS             complement(35695..36351)
                     /gene="rpe"
                     /locus_tag="ACL3F5_000511"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0514365.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(36362..37240)
                     /gene="rsgA"
                     /locus_tag="ACL3F5_000512"
     CDS             complement(36362..37240)
                     /gene="rsgA"
                     /locus_tag="ACL3F5_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0514366.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(37242..38114)
                     /gene="rsmA"
                     /locus_tag="ACL3F5_000513"
     CDS             complement(37242..38114)
                     /gene="rsmA"
                     /locus_tag="ACL3F5_000513"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0514367.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALNQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(38365..38658)
                     /locus_tag="ACL3F5_000514"
                     /pseudo
     CDS             complement(38365..38658)
                     /locus_tag="ACL3F5_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(38651..39292)
                     /locus_tag="ACL3F5_000515"
     CDS             complement(38651..39292)
                     /locus_tag="ACL3F5_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514368.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(39294..41324)
                     /locus_tag="ACL3F5_000516"
     CDS             complement(39294..41324)
                     /locus_tag="ACL3F5_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0514369.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(41401..41697)
                     /locus_tag="ACL3F5_000517"
     CDS             complement(41401..41697)
                     /locus_tag="ACL3F5_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0514370.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(42017..42928)
                     /locus_tag="ACL3F5_000518"
     CDS             complement(42017..42928)
                     /locus_tag="ACL3F5_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGR0514371.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYDKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGQPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(43000..43560)
                     /gene="rnmV"
                     /locus_tag="ACL3F5_000519"
     CDS             complement(43000..43560)
                     /gene="rnmV"
                     /locus_tag="ACL3F5_000519"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0514372.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(43560..44333)
                     /locus_tag="ACL3F5_000520"
     CDS             complement(43560..44333)
                     /locus_tag="ACL3F5_000520"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0514373.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(44638..45378)
                     /locus_tag="ACL3F5_000521"
     CDS             complement(44638..45378)
                     /locus_tag="ACL3F5_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGR0514374.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEATPEYKPETTPGGDKGGNTGNSDANANAGGGSQAGGPAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRPVAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSA
                     SSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(45554..45688)
                     /gene="rpmH"
                     /locus_tag="ACL3F5_000522"
     CDS             complement(45554..45688)
                     /gene="rpmH"
                     /locus_tag="ACL3F5_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0514375.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(45833..47047)
                     /locus_tag="ACL3F5_000523"
     CDS             complement(45833..47047)
                     /locus_tag="ACL3F5_000523"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0514376.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(47203..47496)
                     /locus_tag="ACL3F5_000524"
     CDS             complement(47203..47496)
                     /locus_tag="ACL3F5_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514377.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            47658..48110
                     /locus_tag="ACL3F5_000525"
     CDS             47658..48110
                     /locus_tag="ACL3F5_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0514378.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(48145..49533)
                     /locus_tag="ACL3F5_000526"
     CDS             complement(48145..49533)
                     /locus_tag="ACL3F5_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0514379.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            49599..50561
                     /locus_tag="ACL3F5_000527"
     CDS             49599..50561
                     /locus_tag="ACL3F5_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0514380.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLEHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        14497 a        11587 c         9609 g        15009 t
ORIGIN      
        1 atttgacttt cctaataaag ttgttcatat cttatttcaa gctactatat ataatctaaa
       61 aacttgaatc aaaaatcgaa aaagtagcgg atttctccac tgctttaaca gcttattctt
      121 caatttcgat ttcaagttca tcgcctaagt caagcgtaac ttcttcattc actgctcctt
      181 ctttctttgg ctcatctttt ttgttttcag tatcttgttc tgaaacttct tctccatcaa
      241 tcaagccaaa tttagaacgg acttgcttat caatttcatc aaagatttct gggtgctctg
      301 ccaagtattt cttagcattc tcagaacctt gcccaatttt ttcatctttg taagaatacc
      361 aagcccctgc ttttttgata atatccaaat cgcttgcaat cttcaaaagc tcaccagtct
      421 tagaaattcc ttctccgtac ataatttcaa ctacggcttc cttaaacggt ggagctacct
      481 tattttttac aaccttaatc ttagtttctt taccgacatt ggtttctttt tggtcaccag
      541 ttcccttaat ttgtgtatta ccacgaacat ccaagcggac tgaagcatag aatttcaaag
      601 cacgtccgcc cggtgttgtt tctggatttc caaacatcac tccaactttt tcacgcaatt
      661 ggttgataaa aatggcaatt gttttggttt tattgataga ggcgccaagt ttacgcatgg
      721 cctggctcat catacgagcc tgcaaaccaa catggctatc tccgatatct ccatcaattt
      781 ccgcacgagg aacaagggca gcaactgagt cgactacgac aagatcaact gcacctgagt
      841 caatcaattt tcccgcaatc tcaagacctt gctctcctga gtctggttga gacaagagca
      901 attcgtcaat attgacacca agggccgcag cataagctgg atcaagggca tgttccgcat
      961 cgataaaggc agcaatccca ccttcttttt gcgcttgtgc aactgcatga agggcaaccg
     1021 ttgtcttacc agatgactct gggccataga tttcgatgat acgtccctta ggataaccac
     1081 ctgagccaag ggcaatgtca agagctaaag aacctgagct catcacttgc accttttgct
     1141 ccgcacgttc acccaaacgc atgattgatc ctttaccaaa gtctttctca atcaatttaa
     1201 gagcgtcatt caaggccttt tcacgttctg ccccaaattt ttttgaaatt tcttctaatt
     1261 tttttggttt tttcgccatt ctattctcct acattctaat gatcctcaga cctatctact
     1321 attatatcaa aagttagtca cttaataaag ccttgcgaac taggttaaag gcatgcataa
     1381 ccgcaatgtg acgtacatct gctcggcttc tgcctccaat attaaccttg ataacctcag
     1441 ttccttgatc ttgcgccaag cctatgaaga ctgtcccaac tgggtgtcct tctaggctat
     1501 ctggtcctgc cactccagtc aaactaattc caaaatcaga ctgggtcttg cttcgtgcct
     1561 gctcagccat cttctgagct gtaaattcag acaccacacc atgttcttcc aaattcttgg
     1621 caggaatatc caacatcctt gatttttcct ccaagctata ggtcacaaaa ccacccttaa
     1681 atatacttga aactccagaa aaattcgcca cggtagcttg gaaaagacct gccgtcaaac
     1741 tctctgcagc cgcgatggtt ttcccttgcc ttttcagttc ttctaccaca atgctggcta
     1801 aactagtttc ttccccataa ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct
     1861 ggcagtccaa gatttgattt tccaagatat ccagcgcttg attcgcctct tcttgactgc
     1921 tagcctttgt tgacagacgt agagtgactt ctcctgtctt ggcataaggg gccaaggtag
     1981 gatcgatctg attatcaatt aaatcagcca aaatcgtaac cagctggctc tcgccaatcc
     2041 caaagaaacg aagaactcgg gaatacagct tgctccctgt catcaacttg ggtagaagtt
     2101 ggtttaagac catgggtttc aattcacttg gcggacctgg aaggacgaca taggtcactc
     2161 cgtctacttc taattttcct ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc
     2221 cttctacaat ttgagcttgt ctttcgttat tcggtgttcg ggcatagtct ggtcgcaggg
     2281 caaaaaagat atccaacttc tcctgagcct gaggatcaaa gactaatgct ttccctaaaa
     2341 atttagctag ggtttgtttg gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa
     2401 tcaccagact gctacgttga ctggcaatct caagcaaaga caagagacga acttcattgt
     2461 ctcctacagc cgtctgaaaa tatacatcta ccccaatctc agctagtttt tccgacaaaa
     2521 actgggcatt ggtgttgaca atctgtcctg tcaaaatctc tgttccaaca gcaatgattt
     2581 ctgctttcat gtttcctcct acctatctat tcgtattttt ttgaaaaaat cgcaggaatt
     2641 ttcctacgat tgatttttta tttgtatcaa aagttaatta tcttcatcac caacaggtgc
     2701 tctgccaaat aaatcttcaa ataaaaccgc attggtttca agctgagtaa cttcttcttg
     2761 tcccaaagaa cgtcggagta tattttgcat ttccaacata tgtgctctcg aaacaatctg
     2821 gtaagaaaca ccttgaagta tctctccttc accctgcaac tgctgagttt caatggtttt
     2881 aaatgaatct ttatagccta gcaagttagg gatacttttt gcagacaaat caatattggt
     2941 ctgcatattg tcactcaaag cttttagaat ctcttgataa tgaccaatgc tatttaaact
     3001 gagagctttt tccatgactt tttgaataac ttcacgttga cgtttttgac gaccataatc
     3061 cccctcagga tcttggtaac gcattcgtgc atagactagg gcttcttctc ccccaatatg
     3121 ttgctcccca acaccgatag aaatagtatt aaattcttct tggtcactga tagaaattgg
     3181 gaaacctagg atattattga ctgtaatacc tcctactgca tccactagtt tttgcaaccc
     3241 tctcatattg accatcacat agcgatcaat atggatattc atcatttttt gaatggtttc
     3301 tatagcaagc tctgctccac catctgcata tgctgagttc agtttcgctt catgagcctg
     3361 accattccct gattcaatgc gcgtcagaat atcccgctct aaactcatca ttgttgtttt
     3421 tttcgtttta ggattcactg tcatcaagat catgctatca cttctaccga cccaagtttc
     3481 agttcgttca acatttccgg tgtccactcc cattaacaga atggttagag gttcagtcgc
     3541 ttcaataacc ttggtttctt cgccgatttt tttataggtt ttagctaagg tttctgtccc
     3601 ttgttgataa atagtataag caaaaacacc tactcctact acagttacag aaagtaaagc
     3661 tagcaccatt ccaataattt ttttaaccat atttctacta acctatcagt ttacccatca
     3721 agtaaacatc gataaatttc ccttcttcta tatatgcccc acgctcttgg ctaccttcaa
     3781 tgacaaagcc atgcttttga taaagatgga ctgctgcttg attacgagtt tggacagtca
     3841 gttggagacg acgcagaatg ccacttgctt gtgcccactc tatcgcttct tctagcaaca
     3901 aacttcccaa gccattattc caatatcttt ttccaatcac aatgaagaga tctccaatat
     3961 gacggactct cttacgctga tcagctgtaa tatttacaat accagcaatt ttgccattta
     4021 agaatgcaag taaggttatc tgattgtccg aactagcttg cttgttgagg aatatttcca
     4081 tctcctcact agtcaagaga ataccatctc cgtctaggct ggtaaagtct gtctccaaac
     4141 tcacacgatt taaaaaggcc actaattcag ctgcatcttt gggctctgct tccctaatga
     4201 gcaattcata ctccatattg aagctcctct aacaatttct cagcacgcaa accctttgcc
     4261 tgaaaattta aacggcgtcc atctgcttct tttagaattt ccaattctaa ataagcatct
     4321 ggcaaggcat ctcctaagag atttccccac tcaataacag tcacgccacc accaaagata
     4381 aactcatcca agtcgataga atcagcatct ccttcaatac gataaacatc taggtgataa
     4441 agtggaagtc gaccttcata ctctctcacg atagtatagg tgggactttt aatcatttga
     4501 gaaatctgta atccttttgc aagtccttta gtaaaggtcg ttttacctgc acccagttct
     4561 ccagttaaga ttaaaacatc attctttgct aatagatggc ccaaacgctc ccctaaggct
     4621 tgcaactctt cttcattttt tatgtacata ctcttattat accaaaaact tttcttttgt
     4681 gtctattttc ctactaaact tatcatcata acatccataa aaaacaggct ttctctaaaa
     4741 gaaaatgagc gtaacaatga ccaatacaag atctcggaaa atatgaccat aaaaggaaac
     4801 ttccttctta accgaatttg ggacaagata ggctgcaaaa aacaagccca gtccaatata
     4861 aatcagaagt gagacaatgg tcattggatt tcttaagaaa agaagtgttg ctaaaatagt
     4921 caccaacact gtcttttttc tgtccagcat agcaagaaaa tcgcgcacgt attttttcaa
     4981 gggtaaaaaa atcagcaaat ctagcccaaa taggaaaaag aaggatggca ataaaaagtc
     5041 aactaattct tgctgcagcg tatttttgat gaacaagtta tctgacaaaa caagaacagc
     5101 tcctaacaaa ttaattaaga gtaacatact gtaaaaaagc ttcaccgact tcttactggc
     5161 taggacacta tggacttctt gcttacgagt ataaagataa tttactccag cacagattcc
     5221 tgaaacgaaa accatgcttc cgatgaaaaa agctgtactt tgtttaaagg acaagatgca
     5281 ttccttccat aggaaacagc tactcaaact gatttgaatt aaagctaaca aaaataagat
     5341 tctcattgat ttcatcttct ctctcccttc ctaccaatca ttatactagg agaaaagaga
     5401 gaactgtttc taatcttctc aaatgtctct ttaagacgct aaacaaacac tagagactaa
     5461 tactcaatga aaatcaaaga gcaaactagg tagctagcca caggttgctc aaaacactgt
     5521 tttgagattg cagatagagc tgacgtggtt tgaagagatt tacgaagaat ataaatttga
     5581 aatcatgaaa atccgtcaaa cgggtggttg ttttgtctcg cacctcacgg agcgagacgg
     5641 actcagagtc acataattat aaggctgata gtattaatct aactatcagc cttacaggtt
     5701 atttaacgtt tcagaaaaac tataatgtca agattaacta aacagtatct agttccttca
     5761 aataattttc tatcttcatc aacattaaag gattgttata aatcttacat aactctcttg
     5821 cttctatata ataatttttg acttgttctc tgtctagaaa tttggctcca gcatttccta
     5881 caagaataag tagaggagcc aattggtagc ttgtctgtct ttgtttacag agttcaatcg
     5941 tttcaagagc ttcttggatg gcttcattat atttttcctt tgatactagg tagtgagcgt
     6001 agttgtaacg aactctgatg tagccaaata aaaactcttg atggtccaaa ttttttgtct
     6061 gatacaactc tattaaatga gagtagtttg cctcatattc ttgttcacga cccactaagg
     6121 aatagaaatt agatagagta ttcaacgcct ttaaataaat cagagtattt gaagagactt
     6181 ttaataatat attttccaat gaagaaattg cctcacactt actgtcatat tgatagaagt
     6241 caataatagc tttaatccat tcaaggtaag ttcggtcttc tagtgttaga aaagtacttc
     6301 gttcaatctc tattctataa atatattcca aatcgtcata atttctatcg tctaatagtc
     6361 gagcagacaa ttgcttgaaa ttagagaggt tagatttaat ttcaatttgt tcattaaaaa
     6421 aataatctaa tggtacttca agtcgttgag agagtttgaa caaaaggtct gcggagggaa
     6481 tgaaatgccc tctctcaatt ttactaatct gactttgttc acaaattcct tctgcaagag
     6541 tttgttggga gagtctcaac tcttttcttt tcaatctgaa tttctctgcg agtgtattca
     6601 ttaaagataa taaaccttcc tatttgctta attgcattat aaaattttta gttcaaaata
     6661 gcaagttaaa agaataaata attctttatg gtaataaact aaaaaaagtc aaaaattaca
     6721 taaaaatgct tgaccgaata atatatatat attaaaataa aaacaaggaa aaagaaaagg
     6781 gtttcacgaa tgaagaaaaa tcgtggaatt caaaaattag ctatattagt attactaggt
     6841 gtttttatgc ttagtaacac aattccttac caacagttta ttcagaagaa tagacaattg
     6901 gagattcgag tccaatcaca aaagaagtcc aatggtcttg atgttgggaa ggctgattga
     6961 tttcgtatta ctttaaaatt caactattta gagaaaggta ttctgatgag agcttgtaac
     7021 aataccagat agatattagt aagcttgtta gtttatagag ggcaggggta tttctgccct
     7081 ctgttttaga ataaggaatg cactatgaaa aaattattta tactcatatc caacctgctt
     7141 gctagtttgt tctttgtttg ggtatttacc atttggactg atacatatgt ctcctattat
     7201 taccccaacg ttgttgtaca tgattcttcc cctgaaacaa cttttcagca tgttgctaca
     7261 cgcttggaaa aactagcaga agaaacagat agctttattg cgattcaaca ccaagattct
     7321 aactcagaag gtactacagt tttttcttat acgacctttg gggacggaaa gttgcctgat
     7381 gggcttcagg aaaaaaaact agaagatgct caaagtagta gtgttgaaac aaactatttt
     7441 gtattcgatg gacacctaga tattcacttg ctaagggagg agctaagtca acttggcttg
     7501 actaacatga acctgacaat tccatctaaa ctatctacgt taatggctat ctttagtaac
     7561 ggatttcagt taatcagtct attgattttc atcttaacct ttgtagcact gactttaatt
     7621 agtcaaatta gccaattacg gtcgtcgggc attcgcctca tttcaggaga gaaacggtgg
     7681 tccattttcc ttagaccagt tggtgaggat ttgaaaggga tagctgttgg tttcagttta
     7741 gctggcgtgc tcgccattct tatgcaaaaa attctgtcgc ttccaacgca atccctaatg
     7801 accataggag caggcttgct cagttataat ctcatcttgt tgtcgatctc cctgtttttc
     7861 gctcaactct tcgcagttgg gataaaaaag atacacctga tgcagattat aaaagggcaa
     7921 gtgcctgtca gaggaatcat tagtttgatt ttaatcggtc aactattagc gattattatt
     7981 gtaacgctgg gaatagggag tagcttaaag tattcccaag cctggcaaca gcatcggatt
     8041 ggacaagagg cttggagtca ggaaaggcaa ctgattaccc tatcaatcag ccgtgaagga
     8101 acgagtcctg gttttgatga acaagctcaa aggaaactca gaacttggta tcaattgatg
     8161 gatctggctg tttcagaaca aaaggctttc ttatctagac accagttaat tgaccgtact
     8221 ttgcaaaatg gcatggcttc ctccaaaaac ttgataacct ctacagaatg gcacgattac
     8281 aacccgaatg gcaatgtcct tatcgtcaca ccgcaatact tggagcgtca aaacattcct
     8341 gtagatacaa ctattgagca aaagatgaat caccttgatg taggggagtt tgtcttattg
     8401 ctgcctgaac acctccgttc agaggaagaa cattataaat ctgtttttga agacgactta
     8461 accagtcgca tgtctagtca agatgaacga cagcaaatga ctgctacggt aggttattta
     8521 gaatcaggtc aggatcgttt tgtgtataat acgaccccta tttcttacca gcagtttttg
     8581 aaagatccaa tcatcattgt tataacaccc caatcaactg gtccacagtc cattttgttt
     8641 tggatagacg cagtacagaa ctacgttctc tttaatcaat tgtctgatgc ccaggagctt
     8701 atccagagac aaggcattga aaattgggtc tcagaaatgc aaacaggtta ccacaactac
     8761 atcacattat tggataatat ccagagggaa cgttgggtaa tgctagcagg agctgtgctt
     8821 gggattgcaa cttcaatctt gttgtttaac actatgaata ggctctactt tgaagaattt
     8881 agacgtgcca tttttatcaa acgcattgca ggtctcaggt tcttagaaat ccatcgcact
     8941 tatctctttg ctcaactggg tgtgttttta ctgggatttg ttgcgagtgt atttcttcag
     9001 gtagaggtag gagttgcttt cttagtcttg ttactcttta ctggtctatc tcttttacag
     9061 ttacatgtcc aaatgcagaa agaaaacaag atgtccatgc ttgttttgaa gggaggttaa
     9121 tatgattgaa cttaaacagg tgagtaaatc ttttggagaa cgagagttat tttcgaatct
     9181 ttcaatgaca tttgaggctg gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa
     9241 aacaaccttg atgaacatga ttgggaaatt agaaccttat gatgggacga ttttttaccg
     9301 aggtaaagac ttggccaatt ataaatcgag tgattttttc cgtcacgaat tgggctacct
     9361 cttccagaac tttggcttaa ttgaaaacca aagtattgaa gaaaacctta agctaggtct
     9421 cattggtcaa aagttgagtc ggtcggaaca gcggttgagg cagaagcagg ctttagaaca
     9481 ggtcggcctg gcttatcttg acctagataa gcgcatcttt gagttatcgg gcggagaatc
     9541 gcaacgagtt gccttggcaa aaattatctt aaagaatcca ccctttattc tggcagatga
     9601 gccaacagct tcaatagacc cagcaacctc tcagttgatt atggagattt tgctatctct
     9661 tcgagatgat aataggctaa tcattatcgc aacacataat ccggcaattt gggagatggc
     9721 tgatgaagtg ttcacgatgg atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg
     9781 agttactgaa atattatcat gaatcaagaa ttggagttaa tttagaattg tactttatta
     9841 atattgaggt aactttttct tgataaagga ggaaatagtg gagaggaagt tagaatgaaa
     9901 aaattcgaca attatattat tgagaagcct tgcgattcta attcagataa actgcaaaaa
     9961 atcttaataa ttgaaaattt ggtagatgat attttgcaat ttcctctcag aatcaataat
    10021 agtgtaggag agattttcct cctacaaccg tttcaaaaga aaactatctt tattccatgt
    10081 tattttgagg aagatattgt gaaagtcaag gatgatgata aagttgagtg gaatttgtta
    10141 gaatttcaaa aatttagagc atttttggct tagtaatctg tgttgaaggc tcaaaaccta
    10201 tggtaaaaaa gtcgctttga aaacgtattg cctccaaaga tttagttaaa taatgattta
    10261 acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga gaaaaggtgg
    10321 gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata gtcaattgaa
    10381 acaagaacag gacaaaagaa ccttttgtgc catatttttc tcctttcgct ttacaattgg
    10441 cttgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc gacgcgcacc
    10501 cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta atagtcactt
    10561 aatcaaaaaa acgcaccata tcaaaaacta aaaagtttga tatcatgcgt catgtcttaa
    10621 actaattgac tatactttct attcaaatga gcttttaacc aattgattga gccaatccac
    10681 tcttaaaacc aaagagcaat ttctcgctta gctgactctt ctgaatctga accatgtaca
    10741 acattttgga taacctcatt ttctccagca gcttttgcaa agtcacctcg aatagtgcct
    10801 ggtaaagctt cttctggacg agttgcaccc atcatggtcc gccaagtttc gattactttg
    10861 ggaccagaaa tgacacccac aagaactgga cctgaagtca tgaattcacg aatcggtagg
    10921 taaaaactct gaccaaccaa gtcctgatag tgctggtcaa tcaactcttc tgaaacctgt
    10981 gaacgaaact ccaatttttc gattgtaaat ccacgttgtt cgatgcgctt taacacttca
    11041 cccactagcc ctctttttac accatctggt ttgatgataa agaatgtttg ttccataccc
    11101 gtctcctttg tcagcttctt tcttttattt taccacattt cgtggaaaaa tggagaaagt
    11161 tttcagaaga gagaatgaga gaacccgagg gttctctcat tctctcttat tctactgttt
    11221 cttccacagt ttcaacggca gtatccacaa ctacttctgt tgtttcttca tttccttctt
    11281 cctctactgt aggattaagg tattcttctt cgttgacagc atgtggttca aggttacggt
    11341 aacgggccat accagtacca gctgggatga tcttaccgat gataacattt tctttaagtc
    11401 caaggagatg gtctttctta ccacggatag ctgcgtcagt aaggacacga gttgtttctt
    11461 ggaaggaagc tgctgacaag aaactgtttg tttcaagtga ggctttggta attcccataa
    11521 ggactgggcg acctgtcgct ggaactccac ctgcgataag gacatctttg ttggcatctg
    11581 taaagtcatt gatatccatg agggtaccca tgagaagatc tgtatcacct ggatccatga
    11641 cacggacttt acggatcatt tgacgaacca ttacctcgat gtgtttgtca ccgatttcta
    11701 ccccttggct acggtaaact ttttgtactt caccgagaag gtacgtttca actgacaaga
    11761 catcacgaac tgcaaggaga cgttttggtt ggatagaacc ttctgtcaga gcagcaccac
    11821 gcgctacttg gcccccaact tcgacacgca tacgagctgt aaatggaacg acatattcac
    11881 cttcgccagt ttcaccctta acaaagactt tcttggtacg agttgatgca tcttcttcga
    11941 tagcagtaac ttgtccttta acctctgtga taaccgcttc ccctttagga ttacgggctt
    12001 caaagatttc ttggacacga ggaagaccct gagtgatatc ggtatttgag gcaaccccac
    12061 ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc cccgatagat tgggcagcaa
    12121 ttgtaccaac tgcttcacca acttcaaccg catcaccagt cgccaagttg ataccgtaac
    12181 agtgacggca gacaccgtga cgagtgttac atgtaaatac agaacggata gtcacttctt
    12241 ccacaccagc attgacaatt tcacgcgcct tgtcttctgt aatcaattca tttggaccaa
    12301 taatcactgc accagtttct ggatgtttaa cagttttctt agtgtaacga ccgttgagac
    12361 gctcttcgag agactcgatc atctcttttc cttctgcgat agaacggatc aagagaccac
    12421 ggtcagttcc acagtcgtcc tcacggatga taacgtcttg ggcaacgtcg accaaacgac
    12481 gagtcaagta acctgagtcg gctgtcttaa gggccgtatc ggtcatacct ttacgagcac
    12541 cgtgagttga gaagaacatt tccaataccg acaaaccttc gcggaagttt gaaaggattg
    12601 gcaattccat gatacgtcca ttcggagcag ccatcagacc acgcataccg gcaagctgtg
    12661 agaagtttga gatgttacca cgggctccag agtccatcat cataacgatt gggttcttag
    12721 gatcttggtt agcaatcaag cgtttctcaa gtttttcacg ggcagcacgc cattcagctg
    12781 taacagcatt gtaacgctcg tcgtctgtga tcataccacg acggaattgt ttggtgattt
    12841 gttcgacacg tttgtgtgat tcttcaatga tttcagtctt gtcatcaacg actgggatat
    12901 cggcaatacc cactgtcaat cctgcaagag ttgagtggtg gtaaccgagg ttcttcatgc
    12961 ggtcaagtag ggcagaagtt tctgtcgtac ggaaacgttt gaagatttca gcgatgatat
    13021 ttccaaggtt tttcttcttg aatggagggt tgagctcaag attgctgata gcttccttga
    13081 tatctccacc aagtggcaag aagtatttag ctggaacacc ttctgtcaag ttggcattgt
    13141 ttggttcttg caagtatggt agcccctctg gcatgatatc gttgaagaga attttaccaa
    13201 ctgttgtaag caagacctta tgtctttgct cttctgtcca aggcttgttg aggctgtctg
    13261 ttgcgatacc aacacgtgag tggaggtgaa cataaccatt gcggtaagcc ataaccgctt
    13321 cgtcacggtc tttgaagacc attccttcac cttcgcgacc agcttcttcc atggtcaagt
    13381 agtagttacc caaaaccatg tcctgagatg gagtaactac cggtttccca tctttcgggt
    13441 tcaagatgtg ctcagcagct agcatgagga tacgagcttc tgcttgtgct tcttctgaaa
    13501 gtggtacgtg gatggccatt tggtccccgt caaagtcagc attgtaggct tcacagacaa
    13561 gtgggtgcaa gcgaagagcc ttaccatcaa ttaagactgg ctcgaaggct tggataccca
    13621 aacggtgaag ggtcggtgcg cggttcaaaa gcactgggtg ttctttaatc acttcttcaa
    13681 ggatatccca gatacgctca tctccgcgtt ccaccaagcg tttagctgct ttgacgtttt
    13741 gcacgatatc acgggcaacg atttcacgca taacaaatgg tttaaagagt tcaatcgcca
    13801 tttcacgtgg cacaccacat tggtacatct taagagttgg accaacggcg ataacggaac
    13861 gtcctgagaa gtcaacacgt ttaccgagca agttttgacg gaagcgtcct tgtttacctt
    13921 taagcatgtg gctcaatgat ttcaatggac ggctacctgg tcctgtgatt ggacgaccac
    13981 gacgaccatt gtcaatcaaa gcgtcaactg cttcttgaag catacgcttc tcattttgaa
    14041 cgatgatacc tggtgcattt aactcaagca aacgagccaa acggttgtta cggttgataa
    14101 cacggcggta aaggtcattc aagtcagatg aggcaaaacg gccaccatcc aactgcaaca
    14161 ttggacgaag atctggtggg ataaccggaa ggatgttaag aatcatccat tcaggtttgt
    14221 ttccagactt gtaaaaggca tccaaaacat ccaaacgacg gatggctttg acacgttttt
    14281 gtccagtagc tgttttcaat tcttctttga gttcagcaat ttctttttca agatctactt
    14341 gcttcaaaag gtcttggatg gcttccgcac ccatcttggc aacaaatgaa ccataaccat
    14401 attcgcgcaa gcgctctcgg tattcgcgct ctgtcatgat agacttgtgc tcaagtggtg
    14461 tatccttagg atcaatcacc acataagccg caaaatagat aacttcctcg agggcacgag
    14521 ggctcatatc aagggtcaag cccatacggc ttggaatccc cttgaagtac cagatgtgag
    14581 atacaggagc tttcaattcg atatgtccca tacgctcacg acgaactttc gtacgcgtta
    14641 cttcaacccc acagcggtca caaacaattc ctctgtaacg aatgcgtttg tacttaccac
    14701 aagcacattc ccagtctttt gtaggaccaa agatcacttc atcaaagagt ccttcacgtt
    14761 ctggtttcaa ggtacggtaa ttgattgttt caggtttttt gacttctcca taagaccatg
    14821 aacggacttt acttggagaa gctagggtga tttgcatact tttaaaacga tttacatcaa
    14881 ccactatttc ttccctttct attctaagtg aactgcttat tcttgttcag cagcttcttc
    14941 tgttgcttcc gcttttgttg ctttctcagc ttcttcagct tcaaaggctg ctttagcctc
    15001 ttgggctgct ttttcgcggg ctttttcaag gtcatctacg tggatgacat cttcgtccat
    15061 tccttcatcc aagtcgcgaa gttccacttc ttggtcatct tcgtctagga cacgcatgtc
    15121 aagaccaaga gattgcaatt ctttgacaag aactcggaag gattctggaa cacctggttt
    15181 tggaattggt ttgccttttg taatagcttc ataggctttc aaacgtccgt tgatatcgtc
    15241 cgacttgtaa gtcaagattt cttgaaggac atttgacgca ccgtaggctt caagagccca
    15301 aacctccatc tcaccgaaac gttgtccacc aaactgagct ttacctccga gtggttgttg
    15361 ggtaacagtt gagtaaggtc cgactgaacg cgcgtgcaat ttatcgtcaa ccatgtggtg
    15421 gagtttgatc atgtacatga ctccaacaga aacacggtta tcaaatggtt cacctgtacg
    15481 tccatcgtaa aggattgtct tggcatcgct atccatacct gcttctttaa cagttgacca
    15541 aagatcttca gaacttgctc catcaaagac tggtgtcgca atgtgaatac caagagtacg
    15601 agctgccata ccaaggtgaa gctccataac ctgaccgata ttcatacgtg atggcacccc
    15661 aagtgggttc aacatgatgt cgactggagt tccgtctgga aggtaaggca tgtcttctac
    15721 aggaacgata cgagagacaa cccctttgtt tccgtgacgt ccggccattt tatctccgac
    15781 cttaatctta cgtttttgag cgatgtaaac acgaaccaac atgttaacac ctgattgcaa
    15841 ctcatctcca tttacacgtg taaagatctt aacatcacga acgacaccat cggcaccgtg
    15901 tggtacacga agagaagtat cacgcacttc acgagacttg tctccaaaga tagcgtgcaa
    15961 gagacgttct tcagctgaaa gatctttctc acccttaggt gttactttac ctacaagaat
    16021 atcaccttct ttaacctcag caccaatacg gataatcccc atttcgtcaa ggtctttgag
    16081 ggcatcttca ccaacgtttg gaatttcgcg agtgatttct tcaggcccaa gctttgtatc
    16141 gcgcgtttct gattcgtatt cttcaaggtg aacagatgtg tagacatcgt ccttcaccaa
    16201 gcgttcgctc atgataacgg catcctcgaa gttgtaacct tcccaagtca tgtaggcaac
    16261 gattgggttt tgtccaagcg ccatttctcc attttccata gaaggtccgt cagcgatgaa
    16321 atcgcctttt tcaacgacat caccaacttt tacgagagtg cgttggttgt aagcagtacc
    16381 tgagtttgaa cgacggaatt tttggatgtg gtaaacatcc aatgaaccat cttcacgacg
    16441 aacttctacc ttgtcagcat ctgcgtaagt aactttacca tcatactgag caatcacagc
    16501 cgcaccagaa tcgtgggctg cttggtattc cataccagta ccaacgtaag gtgcctgagg
    16561 attaatcaat ggcacagcct gacgttgcat attggctccc atgagggcac ggttggagtc
    16621 atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacctgtt ttggtgaaac
    16681 gtccatgtag tcaacaatat tagctggata ctcttggttg accccttggt gacgtcccat
    16741 gacaatcttc tcagcaaagg ttccatcttc attcagacga gagttagcct gagctacagt
    16801 atattcatct tcttcatcag ctgtcaacca aacaatttcg ttcgtgacaa cacctgtttc
    16861 acggtcaacc ttacggtatg gtgtttgaac aaaaccatat ttgttcaagt gtccgtaaga
    16921 tgacaagtta ttgatcaaac cgatgttagg tccttcaggt gtctcgattg gacacatacg
    16981 accatagtga gtgtagtgca cgtcacgcac ttcatatcca gcacggtcac gagtcaaacc
    17041 accaggtcct aaggctgaca aacggcgttt gtgagacaac tcagaaagcg ggttgtgttg
    17101 gtccatgaac tgtgacaact gtgatgaacc aaagaattct ttaactgcag ctgttacagg
    17161 acgaatattg ataatttgtt gtggtgtcaa gacttcattg tcctgaacag acatacgttc
    17221 acggacatta cgttccatac gagaaagtcc caaacgtact tggttggcaa gcaattcacc
    17281 aaccgcacgg atacgacgat ttccaaggtg gtcgatatca tctacacggc caagtccttc
    17341 agccaagttg aggaagtagc tcatctcagc aaggatatct gcaggagtca ccgtacgaac
    17401 cttgtcatct gggttagcat taccaatgat cgttacgacg cgatctggat cagttggagc
    17461 aataaccttg aatttttgaa gaacaacagg ctcagtcaca acggctgcat cgtttgggat
    17521 gtagacaatc ttgttcaagt cgccatccaa atggctttca atgctttcaa tcacgctacg
    17581 agtcataatc gtaccagctt ctaccaagat ttctccagtt tcagggtcta ccaatggctc
    17641 tgcaatggtt tggttgagca aacgtgtttt aacattgagt tttttattga ttttgtaacg
    17701 accaactgct gccaagtcat aacgacgtgg gtcaaagaag cgagctacaa gcaagctacg
    17761 tgagctttca gccgtcttag gctcacctgg acgaaggcgt tcgtaaattt ctttcaaggc
    17821 ttcgtctgta cgagagtcca ttggattctt gtggatatct ttttcaacag tgttgcgaac
    17881 caattcgctg tctccaaaga tatcaaagat ttcatcatca cctgagaaac caagagcacg
    17941 aaccaaggtt gtaaatggaa tcttacgagt acggtcgata cgagtgtagg tgatatcttt
    18001 tgagtcgctt tcaagttcca accaagctcc acggttaggg ataacagttg aaccatagcc
    18061 caccttacca tttttgtcta ctttgtcgtt aaagtaaaca cctggtgagc ggaccaactg
    18121 agaaacgata atacgttcac caccattgat gatgaaagta cccatttctg tcatgattgg
    18181 gaaatcacca aagaaaactt cttgggtctt gatttcgcct gtttctttat tgatcaaacg
    18241 gaaggttaca aaaattggtg ctgagtagct agcatcgtgg atacgagctt cttctagcgt
    18301 gtattttggt tccttgattt catatccaac aaattccaac tccattgtgt ctgtgaagtt
    18361 tgaaattggc aatacatctt caaacacttc cttaagaccg tggtctagga aagctttgaa
    18421 tgagtcagtt tgaatttcaa tcaaatttgg taagtcaaga acttctttga ttcttgaaaa
    18481 actacgacgg gtacgatgtt tcccgtattg aacgtcatgt cctgccaaga tgattctcct
    18541 ttgtaaataa gttccaagcc ttgtcaatca ggcttttcta atcgtcatat ggttgtaaac
    18601 cccttatcac cgtgtcctct tgacgaattt tcagaatctt taagcctctg ttacaaatgc
    18661 tcataatctt gaaaaaaagc acaaaaagag cagctaaatc tgactttttc agaagattta
    18721 actgctgtga gccttgtctg gacaatattt cagacaaaac ctacgacaaa tgattaccca
    18781 tattataccc tatttagcta gatttttcaa ggggtttcag taggtttttg gtaaattttt
    18841 tcccatagaa aacttggcat cacattcgaa tcacgctatg gtacaaaaaa ctgaaaaaac
    18901 tattgactga aaatcatttt caaggtataa taataaacgt taaggcggta tagccaagtg
    18961 gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa tccgtctacc gccttctata
    19021 acttgattta tcaggtttca aatgaacaga aagcccaatt tgaagggctt tttttatttt
    19081 ccctcgaata aatacgtata actttaaaaa cttttggagc gagtttgtgg cagagttctt
    19141 tccatagcat aattcccttt tgaaatcaat tgaaaaaagc ttcgtcacgc ctggtgacaa
    19201 aagcctctag tttattctgt ttcttcttct atttcgactt ctgtgatttg gacttttacc
    19261 ttggtaacac gtccattctt cactttatca ttggttaaga taaactgttt gttttggctg
    19321 accaattcat agctgagttt ctcagtcgtt ggaatggttc ccactcctgt caaataataa
    19381 ccagcgatgg tatcaacgtc atcactttcc agctcaacat caaagtaatt attgaaatca
    19441 ttgagggtca tagttccttg aacaatgtag gtatcctcgc caatctgatg aacatctatt
    19501 gctgctttgt ccgtttcatc atcaatttca ccaacaattt cctctaagag gtcttccaaa
    19561 gtcactaaac cagccatacc accgtattca tccagcaaga ttgccatttg tctttgggta
    19621 tttcgcagtt cttttagcaa gtcatccaca aaaatagttt caggtacaaa aagtggatct
    19681 tgtaaaattc tcttccaaac aatattgtca aaaccgtcca caaagcctgc cttaaggaga
    19741 ctcttggtgt gaatgattcc aattacattg tccttatccc catcataaac cgggatacga
    19801 gaataatttt gttttaaaat actttggata atggcttgac tatcatcctg aatatccacc
    19861 ataaaggcat ccgttcgagg aaccataacc tctcgtgcca tcagttcatc gagcgaaaag
    19921 acaccttgta gcatctcaat ctcatcagca tccaatgttt cttcactatt tgtcagcata
    19981 taggcaattt catcacgggt cattttttca tccgcatcat cgaatgacat aggagtcaaa
    20041 tggctcaaga aattggtcga agcagctaaa agccaaacaa aaggactgac tagttttccg
    20101 atcccaatga taaccggcgc tgtacgaatt gccaaggcat cctttagatt aagagcgatt
    20161 ctcttaggat ataattcccc aaaaacgatg gaaatatagg tcaaaaatgc caaggataga
    20221 aaagttgcca cggcttgtgc tgtttcgcca ttcccaagcc aagaggcaat cacacgtcct
    20281 agagtatcag ttaaactcgc ccctgataag attgtaatca gggtgattcc tacctgaatg
    20341 gttgataaaa agtggttagg attttctagt accttcagca ggcggatgta gcgtctgtct
    20401 ccttcttccg ccttttgttc aactcgggca cgattaagag aaaccatggc catttctgtg
    20461 gctgagaaaa aggcatttaa taccgtcaag ataaacaata aaacaaattg tagcaacaaa
    20521 ttctgactac ttgggtcttc catagttctt ctcctaaaat agtatcttat cctttattat
    20581 atcacaaaat ttaatccaat acatattatt tttttcttag cgtaacttcc atctctctcc
    20641 caaaactgga agttagtcta agacggattt ccactgattt cacgcgtttt tctcatacta
    20701 aaagctaggt tgtgggaaac tggaagttag ttttagaagt tactattttt tcttagtacc
    20761 tattctagcc ctgcttaaac tagtaaaaag aactcctaca tccataagtg acataggagt
    20821 ttaggcttat cttttactga gttacagtta cttctccagt tcggtaatcc agttgaagtc
    20881 ccttttgaac attgggaact agaacattga attccaattc tccatccgaa gacttggctt
    20941 caatctgtga agctgaggga actaaatcct cgtttgaagc gtagtaaagg gttacacggt
    21001 aacggacacg cttgttttgg tccaaggctt tacgcacctt gctttcatag tagttttgac
    21061 cagtcgaata ctcggcttgt gcctgatttg cccaggctgt ctgaacagca atgtttttag
    21121 gattgcttgt tgaggcatca aaaccatcca aaccaccgat taaggcatag cctaacaaat
    21181 gacctctatc gactgcatgg gtataagagc cctttagatt cttgacctga tgccaacctg
    21241 gaggagtcca agaagttgaa ccattcccag tttctttacg attcttgtac tgacgagtgg
    21301 ccttagacaa gagggcatta gctacggttg gaacagtttc cttgcccact gtctttgttt
    21361 tattgtcagc gtagggctta cttgaaacct tggcatctag atttgtttta ttaccattga
    21421 cgataaaagc acctgagcca ttccactcca gactcccctt tatttgactc ttgactgcgt
    21481 ctgttaagac actctctgcc aatgcttgac taggagcttc agacgcttgt tttttctgac
    21541 taagattggt tttgagacta ttaggtgccg actgcatctg cttgatataa tagctccctg
    21601 tagacaaaag caataacact agcagtccga ttagtgtctg tcttgttttt ttgttcatat
    21661 ttctccttat ctttagaaaa aggctggttc tccagcctaa tttcctgtaa atttatgaat
    21721 caattcctgc cattttgctg gagacaggat agcccatgga tcttgaccct tgcccaagat
    21781 tccataacct accattagac cgattcctag agccagagta cctaaaatca gtactatgat
    21841 gactaaaagt aaacgattga ttacgtagct tgatttctta ttcatcttca tcgcttgcct
    21901 caatccgctg aatcttagca cctagctgcg ccaacttctc atggaaaccg tagtaacctc
    21961 tatccaagtg aaccaattta ccgaccacag tttctccctg tgctaccaaa cctgtcaaaa
    22021 tcaaggctgc actggcacga aggtcagttg aaagaacttc tgctccctgc aaaggctgtc
    22081 caccaacaat acgagctgta tcacggataa tctcagaatg caagcccatg cggcgcatct
    22141 cttctaggtg ttggaaacga ttttcgaaaa ctgtctccac catggttgat tcgccttttg
    22201 caactgtcat caaggctgta aattgagcct gcatatctgt tggaaatcct gggtggggca
    22261 aggttttcac atgaacagct tttagatttt ctagttgaga acgaacacga attccttcgt
    22321 cttcttcaat tacttcaaca cccatttcaa gtaacttggc aatcaaggga cggttgtgct
    22381 cccagacagc gtctcgaatc aagacatcac caccagtcat ggcagcagct accataaagg
    22441 ttcctgcttc gatacggtct tggactacat tgtgagtcgt accatgaagt ttctcaacac
    22501 cagtaatggt tatagtctct gtaccagcac ctttgacctt ggctcccatt tcattaagga
    22561 gaatggctaa gtcaacaatc tcaggctcac gcgcagcatt ctcaatcact gtcaccccat
    22621 cagccagagt cgctgccatc atcaagttct gcgttgcacc aacacttgga aagtccatat
    22681 atatatgagc accatgcaag cgttctgcct tggcttcgat gtaaccagct gtctgactaa
    22741 tcttaacccc catagcttcc agacctttca aatgaagatc aataggacgg ctaccaatcg
    22801 tacaaccacc tggcatggat accttggcat gacccacacg ggcaaggatt ggccctaata
    22861 caacgatgga ggcgcgcatc ttgctgacat acttgtaagg ggcttcctca gtgatgtcgc
    22921 cagtagcatc caccttgaca agatgagctt cctcatcaaa gtcaaccttg gcattcaaac
    22981 caccaactac ctgattcata ataaagacat ccgacaaaat cggaacattc tgcaagacgg
    23041 tctttccttc acttgctaga atagtcgctg ccaacaaggg taagactgca ttttttgctc
    23101 cctcgatcgt cacgcttcct accagacgat tatcgccacc ttgaaccaca attttatcca
    23161 tactcgtttc ctttactctt gatttcataa taatcctcta agcgcttctt gccacaaatg
    23221 atacaggcta ataaagaaag aactcaggat gtagcctatg acaatgctaa aaaaggctac
    23281 taataaacga acttttcttg tattctcatc tgtcactttt aaaaccttct cccatctaac
    23341 aagatccttt aaaaggtaaa aactcacata aataaagaac atatgactac ttagagtgaa
    23401 taataattga accatttgac tattatacca tcttctctgt ttgtgcgcta gtttggaaac
    23461 ttcactcaaa aattagggat tgtttttcaa gtaatcaatc gcatcttgta gggttttaac
    23521 gggcacgatt ttcatatccg tcttgattgt tttagccgct tctagggctg tttggtagtt
    23581 gtttttcgcg tccggatgcg ccttttgttc ttcttcgcta acagggttat caggagcaaa
    23641 gaaaatagca gcacctgccc tagccgaagc tacaaccttc ttatcaatac ctccaatgtc
    23701 tcccacatta ccatcgcggt caatggtacc tgtaccggca acaatacgac cattacgaag
    23761 atctgggtga gctatttgag tatagatagc tagactaaac atgagaccag cacttggacc
    23821 gccaatacca gctgttgaaa agctaattgg gacattgctg attacctctg tacggtcaat
    23881 caagccgatt ccaattccat ttttgccatt ttccaaggtg ataatctttc cttctgcaga
    23941 cttggtttgc ccatcctctt cataggtgac cttgacggaa tcccctaatt tttgagaact
    24001 gacgtaatca atcaagtctt tggaactatc aaaggtctga tcattgactg ctgtgactgt
    24061 atcagagata ttgagaatcc ctttaaaggt tgaattatcc gtcacattca aaacataaac
    24121 tccaaagtac ttgagttcga tatccttacc agctgttttt agtccttgat acttggccat
    24181 attttgcgat gtttgcatgt agaattgatt gattcgcata aattcaacat cggaagaacc
    24241 acctgtagtc tcctgagcac tacgaatatc tgtaaaaggt gtcaaccaag cataaatcat
    24301 atgagctaaa gtagcatgtt gaacaccaac cgtaacgaat tgataggcac cagcttcctt
    24361 atcttctgtg tcatttactt taaggacttg gcgaatatct tccgaaccac ctggaacctc
    24421 tatatagtag ggcaaaggca ccacaaatgc caagaaggtc acaatcaagg ccgcaatgac
    24481 atacaaaggc catctaatct tttttttcat ttcttatttc ctccaaaata ctctcgggaa
    24541 catggcaggc aatatcctga ccaaacttca aaagctctcg aacacctgat gaactgatat
    24601 agagatgttc aggccggcta tgtaaataaa tagtctctat atcagaagac agctgatgat
    24661 tgtagtaatc aaaactagct tcatattgca aatccgccgc attcctcaac ccccgtacta
    24721 ggaaagtagc ccccagtctt tttgcaacat cgaccaccaa tttatcatga gaagccacga
    24781 cttcaacatt ttccaaatgt cccaaagcct tttctagccc ccgtttacga ttttcaagag
    24841 ggagaaatcc ttgtttgtgg ggattaaaaa aaatacccac ataaagctta tcaaaaagtc
    24901 tgctcgcccg ttcaatgata tccagatgcc catttgtcat cggatcaaat gagcctgtga
    24961 ataagccaat cttatctgac atagactgtc accttactaa ttccataaat cttttccttc
    25021 cagataccca gacaggcaat ctcttctgga agttcaacgg ctttatccgt ctcgcacaca
    25081 accataacat cttcagaaaa aagctctctc tcagccattt tttcaatatc tgctacgatt
    25141 tgttccttgg catagggagg gtctaagaaa acgaggtcaa attccccaga tacctgttcc
    25201 aatgcccttt ctgcatccat cttgaggagt tgaaattttc caacttcctt ggtcatctgg
    25261 atattttcag ccacgatggt ctgagcctta cggtctcgct ccaccaaaac agcactggac
    25321 atgccacgcg atactgcttc gatagataaa ccaccactac ctgcataaag gtccaagact
    25381 cgtcccactt caaagtaggg accaatcatg ttaaaaatgg ctcccctaac cttatccgaa
    25441 gtaggtcttg tcgtcttgcc ttctagtgtc ttgaggggac gtcccccata gattcctgat
    25501 acgattttca tactgtttat tataccaaat tatagacaaa aagagaaaga aaaccgaacc
    25561 ttgcggttcg attctctaca aaatattttc gtaagtatcg cggacttctt gaggccaaac
    25621 acttgtttgc acttctccga tgtgtctctt gcgaagtagg aacatggcca tacgagattg
    25681 tccaattcct ccaccgattg tcaatgggaa tagaccattc aacaaagact tgtgccattc
    25741 caattccaag cggtcttcat cacctgtaat ttccacctga cgtctaagag tttcttcatc
    25801 tacacgaatt cccatagaag acaactcaaa ggctccacct aaagactcat tccagacaag
    25861 aatatcacca tttagaccct tgtagccatt ctcagactcg cttgtccagt catcatagtc
    25921 tggtgcacgt ccatcgtgcg gtttaccatc tggcaactcg ccaccgatac caatcaaaaa
    25981 gacggctcca aattctttac aaatcgcatt ttcacgttct ttcggtgtca agtctgggta
    26041 gcgttctacc aattcttctg tatggataaa ggtgatttgt tttggcaaga tagactcgat
    26101 gtcatagcgg gcttcaacag ctagctcagt caggcgaata gccttataaa tcttctcaac
    26161 tgtttctttt agataaacga tgttacgctt accatttggg ataaccttct cccagtccca
    26221 ctggtcaaca taaacagagt gggttgcatc caaggaatcc tcatctggac gaagggcttt
    26281 catgtggaca aagagaccct ctccttcacc aaagccaaaa cgagccaagg tgtggcgttt
    26341 ccatttagca agtgagtgca ccacttcata agtagcatca gggatttgga gaaccttgac
    26401 cgatactgga ttttccacac cagacaggtt gtcctgcatt ccgtcaccga ccttactcaa
    26461 gataggacct tgaacttcga caacttctag cttatctttc aaatactggg taaaagtgtt
    26521 tttgacaaag gaaatttctt cttgttgatg gataaaactt ttcttcatag acaactcctc
    26581 aaaaatttaa taaacgtatt atacacctat ttccaagaaa agaaaagaga aaatttaaaa
    26641 aaaatcagtg tcactcaaaa cactgatttc atagaccttt tagtcattgc gaccaaagat
    26701 acgtagaata cttaggaaaa gattgataaa atcaagatag atgctgagag ccattgacac
    26761 cacccagcct gtcgctacac gaccttgtga ttgttcatag gcgaggcgaa tcttttggtt
    26821 atcccaagca atcaaccctg aaaaaaccaa aaccatggct acgctaatca tataatcaaa
    26881 gaagccacta gccaagaaaa tattgactac catagcaatc agtaaaccaa tgagagctgc
    26941 catcattgct cgaccaatcc cactcaagtc tttcttggta aagataccaa ctgccgccat
    27001 gacaaagaag agaagggcgc tcgatacaaa ggcagataaa actgtacccg gagtatagaa
    27061 agccaccaca aaactaaggg taaagccgtt taaaacggag taaagtaaaa atactggaag
    27121 agcagctgga ctatttcttg aagccatgct actggcaacg aaaaccaaag ccaactccgc
    27181 aaaagtagca atggtcaacc agagacgccc ctgcatcaac aagtaaacca actgagactg
    27241 aaagaccgtc aacataaggc ctgataccaa agcagatagt ccgattccca gaccaacaaa
    27301 ggcataaacc ttagcgtaaa attgattgag acctgcacgg tcatgtataa tagtgtgatt
    27361 catccttttc tccttttctg tgaacatctt tccttgatta taacaaaaaa agttaaaatt
    27421 agcttaaatg gaagattaaa ataccggctg caactgcaac attcaaactc tcggcctgcc
    27481 ccttcatgct aatatggacc aactggtctg cactttcagc cataagggga ctaattcctt
    27541 gaccctcatt tcccataact agtacaaaat tttctataga aggcagttct ctgtaatcaa
    27601 cagaatcttt agatagggtt gttgctagca ctgggatagc taccttttta gtttcgtcaa
    27661 gaagcgctgg actagtcatc cggtaaatgg gcagatggaa atgactacct tgcatggaac
    27721 gtagggtttt gagactgtag atgtctgccg acttatctga aacaatcact cctgtaaagc
    27781 ctgctgcatc cgcagttcga atgatagttc ctacattacc gggatcttgc acatcttcca
    27841 aaaacaagaa cttgccctga ctcaaatcag cttgtcctac ttcttctttt tgaaccaccg
    27901 ccacaattcc ctgtggagtc tgagaatccg ccaaatctag caaaatatcc tctgaaatcc
    27961 agacagtttg cggaaaagca gctaactgat ctcgataatt ttctagggca aagattttct
    28021 caatcgtcac tccagcttgg acagcttctt caaacaagtg ccagccttca atcaaatagg
    28081 cagacttgcg gtattttttt tggtgtaatt tcttggcatt ttttaccaca gaattggctt
    28141 ttgaggttat aatagtcata gaaatattat aacacaatca aaggggtttg gtatgcaaaa
    28201 ggttagaatg attgcccaag gtagggtaca gggagtcggc tttcgttggg gtgtttacag
    28261 cttggcactt gaaattggtg gcatcacagg tcgagtatgg aataacgacg atggcacagt
    28321 ggaaatctta gcccaagcag actcatctgc tatcatggca aaatttatcc aagaaatccg
    28381 aaaaggaccg acaccttttt caaaagtaag ctacttagat gtcaaactaa gcaactttcc
    28441 tccctactct gactttaaaa tcgcaaatta ggtctccaga actattgtat attttgtaaa
    28501 aaaacagtag aatagaaagg tataattttt aaagaaggaa taaaaacagt gaaatctatt
    28561 aaacgttttg cactctcagc tatgggagcg gctatgttgc ttgtcttgac tggttgtgtc
    28621 aatgtcgata aaaccacagg tcagccaaca ggatttattt ggaataccat cggagcccct
    28681 atggctgaag ctatcaagta cttcgctact gataaaggtc taggctttgg tgtcgctatc
    28741 atcatcgtaa ccattatcgt gcgcttgatt atcttgccac ttggtatcta ccaatcatgg
    28801 aaggcaacgc ttcactctga aaagatgaac gccctcaagc acgtccttga gccacaccaa
    28861 acgcgtctca aagaagcgac tactcaagaa gaaaaactcg aagcccaaca agctctcttt
    28921 gctgctcaaa aagagcacgg tatcagcatg tttggcggtg taggatgttt ccctatcctc
    28981 cttcaaatgc ctttcttctc tgctatctac tttgctgccc aacatactga aggggttgct
    29041 caagcaagct acctaggcat tcctctaggt tctccaagta tgattttggt tgcctgtgct
    29101 ggtgtccttt actatcttca atcgctcctt tcacttcacg gagtagaaga tgaaatgcaa
    29161 agagaacaaa tcaagaaaat gatttacatg agcccactca tgatcgtcgt cttctccctc
    29221 ttctcaccag ctagtgtcac actttactgg gttgtcggtg gtttcatgat gattctccag
    29281 caatttatcg tcaactatat cgttcgtcca aaacttcgca aaaaagtccg tgaagaactg
    29341 gcaaagaacc catcaaaagc aagtgctttc tcaacaccaa gtggacgaaa agacgttacc
    29401 cctgaacaac caactgctat tacaagcaag aaaaaacaca aaaatcgcaa cgctggaaaa
    29461 caacgttcga gataagaaga aaaaggctta gctgatttgc taagtctttt tgcaagtcaa
    29521 aagcccgatg tttccatcag gcttcttttc tatccatgta cacgtttcat ataatcttga
    29581 taactttcgg tatccatgag ttttttagcg ttcttgacgc gatctgctgt tggtggtttg
    29641 actccttcga gggaatatgg aattccaagt tcacgccact tgaactcacc catggtgtga
    29701 taaggtagaa tttcaaactt atcaacattt ttgagggtct tgacgaactt accaagttca
    29761 atcaagtcat catctctgtc tgtcaatcct ggaactagca cgtggcgaat ccagacaggt
    29821 tttccaatat ctgatagata ctgggcacaa gccaagatat ttttattggt ttggctagtg
    29881 acaatcttgt gctgttcttc gttgatttcc ttgatatcca aaagaaccaa gtcagtgaca
    29941 gccatgagtt tgtcaaactt ctcaaggtaa cgcggtttat tacggaaagg aagagcacag
    30001 gtgtccaagg tacagtggat tccttgttcc ttagccttgg tgaagagagc aatcaggaaa
    30061 tcaatctgca agagagcttc tcctccactg actgtaatcc cacccttatt tccccagaaa
    30121 ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg tccgttcacg tgacttattg
    30181 gactccatag cccaagtgtc tgggttgtgg caatactggc aacgcatgtg acagccctgc
    30241 aaaaagacaa taaagcgaat accaggccca tctactgacc caaagctttc tgtcgaatgc
    30301 accatccctg tcacttgtcc ataatcaatt gtttcttcag acatatcgtt accttccttg
    30361 aaaacgtttt atagttttat tatatcacga cttgaaggaa aaacaagatt tttgcctatt
    30421 ttttagaaag caatctgttt ttcaatttca ttttcaatct atcatcagat tattcttcaa
    30481 aatcaaagcc atataaggtt gcaaaatagt cctcggggcg ctctgcacgg cggatttgac
    30541 gggctttacc ttcttcggta tagaggattt ccgcagaacg taatttggca ttatactggt
    30601 agcccattga aaatccgtgg gcacctgtat catgaattac cagcaaatca ccgatttctg
    30661 tatgaggcag ttcgcgattg actgcaaatt tatcattgtt ttcacagagt gaaccaacca
    30721 catctaccgc ttcagctggt ccatctggat gggtcacgtt gctaatatga tggtaagctc
    30781 cgtacatagc tggacgcatg aggttgactg ctgaggcatc cacacctaga taggtacggt
    30841 aggtttcctt cttatgagtg actcttgtga ctagagcacc gtgaggtgcc agcataaaac
    30901 gacccaattc ggtgaaaatc ttgacctgac caagacctgc tgacgtaaga acttcttcat
    30961 acaccttacg aactccctca ccaatcaagg cgatatcgtt cggctcctgg tctggacgat
    31021 aattaacacc aataccgcca gaaagattga taaagtctag ccaaatgccc aacttttcct
    31081 tgatttcaac agccagttca aagagctgac gagccaactc tggataatag agatgggtca
    31141 cggtattgga cgctaggaag gagtgaatcc caaaagtctt ggctcctttt tccttcaaga
    31201 tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa cttagcctcc ccaggattgt
    31261 ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt ataacgacaa gagatgattt
    31321 ctggaatgcc tgctactctc tccagatgtt caatatcttc aaaggcatcc aagttaatgg
    31381 tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg cgtgttgttg gaagagaaca
    31441 taatctcaga acccagaaag tccagtttat ggctcatcaa aagctctaca taactagagc
    31501 agtccacacc acaaccttct tcttggagaa ttttcaaaat agctggagtt ggagtagcct
    31561 taactgcaaa atattcctta aagcccttgt tccacgaaaa agcttggttg acggctcttg
    31621 ccttctcacg aatccccttc tcatcataca agtgaaaggg agtcgggaac tcggcaacaa
    31681 tcgcttctaa ctcttctcta ttgataaatg gtgttttcat aagcttcctt ctattctgtt
    31741 tgcaaagaaa ggctgggaca atcgttccaa cctttagttc tatctcttat ttatcttcgt
    31801 caaagatatt gccaacctca acatcgatgg cttggttctt gacatcaata ttggttacct
    31861 tcaagagtga cttgtagtca aactgctttt cacgttcttc ttgggcattg tccgcaaaga
    31921 ccgctacacc tgccagttct gagtcgaact cgcgcaagag actaatcata ccattgaccg
    31981 ttccgccacc tttcaagaag tcatccacaa tcaagacacg gctgcctgcc ttaagactac
    32041 gttttgaaag gaacattttc tcgatacggt caccacttga acctgaaaca tagttgacgc
    32101 taacagttga accttcggta attttcaggt cacggcgcac aatgacaaaa gagacattga
    32161 ggacattggc aactgcattt gcaagtggca cacccttagt tgctacggtc ataaccgcgt
    32221 caattttttg gtccataaag cttttggcaa taatacgacc aatatttttc aagatggctg
    32281 gtgtgctaag caaatcagac agatagatat aaccacctgg caagatacgg tcactttctg
    32341 acaacttggt acgcaagtct tcaaccattt ccttagcatc ctgactcgag atagacggtg
    32401 tgaagatgac acctccgcca gccccagtca ctgtctggat atgaccgatt tcaatttcct
    32461 caaaggcgcg tttgataatg acgatatctt ctgagatgga tgatttagca gactcatact
    32521 tttcagcaaa agtattgaga ctagttagtt tataaggatt attaatcaaa tagttggaaa
    32581 tgacaaccat ccgatcactt cttcttaatt tcatttctat ttcctattcc atttttattc
    32641 aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg ttcaaaacac tgctttgaga
    32701 ttgtcgatag aactgacaaa ccctgtaata tacctgcata tatacatacg acaaggcgat
    32761 actaccctag tttgaagaga ttttcgaaga gtattcattt ttgtctttta cttattatac
    32821 catattcaca taaaaaaacg aacattctta tcctaaaaaa tgctcatttt tcttaaatta
    32881 ttaatctaaa tctggtttat agaaggaacg attatccata gcgaagattt tattggacat
    32941 ctctccttta tccaccaaag ccagagctgt tgacatcatc atcatgcttg catccagatt
    33001 gtcaatcata tggataatct ctgcctccat aatacgtgga cggactggac ttccatattc
    33061 aagcaagccg tggtgactga ggatgacatg acgaagcaaa acgacttctt ccttggtatc
    33121 atcgatgccg agttccataa ctgtcttggt aatttcgcta tcaatgagag cgatatgtcc
    33181 aagaagattg cctctgaccg tgtactcggt ctggtctggt cccgtcaact cgatgacctt
    33241 agccaagtcg tgcaacataa tccccgcata gagcagactc ttattgagct gaggataaac
    33301 ttcgctaata gcgtctgcca aacgtaccat ggtcgccgta tgataagcca accccgtttc
    33361 aaaggcatgg tggttggtct tggcagctgg ataggagtag aattccttat catacttggt
    33421 gtagagattt cggacaatcc gttgccagac aggattttca attttgaaaa tcatttgcga
    33481 catgtagtca cgaatttcct tgacatcaac tggtgacttg accttgaaat cggctgggtc
    33541 attgggttca ccagcttgag gcaggcggag agtaatttga ttgacttgag gggtattgtt
    33601 ataaacttct cggcgtcctt tcatgtggac aaccttacct gcggtaaagg cctcaatgtt
    33661 atgaggttgg gcatcccaga gcttcccatc aatctcgcca ctatcatctt ggaaggtaaa
    33721 ggctaggtag tttttcccag ctcgagtttg cctcaggtca gctgatttga ttaggtaaaa
    33781 gccttcaaat agctcatctt ttttcatgtg actaatcttc atattcttcc tcattttctt
    33841 gaaaatggag tagatcaagc gcaggctcgc cttctgacaa ctcaatgtga cggagcgtcc
    33901 gctcgatagc tatggtacga cggtttaata attcatcaat attgccagag gcatgttgga
    33961 gatgtttttg tgccttgacc agaataccac caaacttgcc aaactcggtc ttgacactgg
    34021 caagagtctt gctgatatgg tcggcactct tttggatatt aagggtcttg aaaccaactg
    34081 atagggagtt aagaagggct gatagggtac ttggtcctgc aacaataatc tgttcttccc
    34141 gtctcaaatc atcaaagaag accggattgc ggacgatttc tgagtagaga ccttctgtcg
    34201 gaacaaacaa aactccaaaa ttggtcgtcc gaggtggtgc tatgtacttg ttcctaatat
    34261 ccctagcaaa acgcttgaca cttgctagga gtgacttacg acagcgttcg atttcatcct
    34321 tgtcacctac ttcataggct tcttccaagc ggtaataatc tgccagtgga aacttagagt
    34381 caattggtag gtagacgtat tcttggtcgc cttgtccggg taacttgatg gcatactcca
    34441 ctcgttcact agagttttca accgttgcgt attctcgttc gtactgggca ggtgtcatga
    34501 tgtcttcaat aatttgcccc agttgcaatt ctcccagaat ccctcgcgtc ttggttccag
    34561 agagaacctt gttaagagct ccgacatcac gggcaactgt ctgcatttct ccaagaccac
    34621 gattgacaga ctccagttgt ttagaaactg tctcaaagga agcctgtaag cgtgtctgca
    34681 aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg ttccaaacgt tgctcatttg
    34741 attcctgcaa ggcttggaga cgttggtctg tcttgtctct agtttggagg agattatctg
    34801 tcatttcttg acggacttgg gtcaggcctt ggtgcaattc aatccgcact tcttgcaaac
    34861 ggtcgctgac agccacttcc aaatcttttt ggtctaactg gctggcttgt ctggcttggt
    34921 caaagcggta atccaactgg tctgacaaat gatctgcctg atcctccaag ctcttactta
    34981 agtgtttctc ctgcctatcc tgcctttgcc aaatcagaaa gagaccagct aggttggcaa
    35041 ttaataatag aataagtaaa ctttccatcc tacctcctat ccttgctatg cagtacgacc
    35101 acataaccat ctgggcaagt taccgacact tccctatcta tatattcgtt agaagcgtac
    35161 acttttttaa agaaaaaatt ttcctctgtc aactcatact tggctccaag aatagtcagc
    35221 tggctatccc gaactggcat aaaggctaga tagtcgtagt ctgaacgagg ttctagctga
    35281 ctggtccctt ctggacaata agtaatcaag ttttgcccat cctcaatttc tatttgatgc
    35341 atatagggtg ccaacttagg attgctaggc agaaagacat tggccaacat atggtcaata
    35401 cggccaccca aggcaccgaa aatagtaacc tgagcctgag gatttttctc aaagatggtt
    35461 aagagagcca attccaaatc ggtatcatct ttttctggtc gggcttggac aaaatgctgg
    35521 gcacgttttt gaatcacctg tcgctcttct tcggtcacag aatcaaaatc cccaactgct
    35581 agagcaagag gcaagtcttc ttccaagacc cagagcgagc ctcgatccac cccaacaaaa
    35641 gcatcaaaat ctgtccgata atgaccgcgg tctccgcctg caaaaacggc aaccctagtc
    35701 cagttgtttt ctgagagttt gtactcgctc attgacatct cccttaaaga cataggaacc
    35761 tgctacaaaa acggtcgcac cagcttcttt ggcttgagca atagtttggt catcaatccc
    35821 accatccact tcgatttcaa agttcaaacc tttttcctca cgaagagcaa ccaactcacg
    35881 aaccttatcc atggtttctg gcagaaaggc ttgcccacca aaacctggat taaccgtcat
    35941 gactaaaact tggtcaacta gatgaaggac gtgcttgatg gcttcaactg atgtgccagg
    36001 attgataacg actgaaggct taactccgag tgaacgaatt ttttggaggg cgccatgaat
    36061 atgaggcgtt gcttctacat ggatactgat gatgtctgca cctgcacgcg caaaatcttc
    36121 cagatgatgc tcagggtttg acaccatcaa gtggcaatcg aaaaccatct tactatgagg
    36181 acgaaggctc tcgaccacac ctgcaccaaa actgatttgc ggtacaaaat gactgtccat
    36241 gatatcgata tgggcatatt ctgccccagt tgcttctaga cgtttgattt cacgttcaaa
    36301 gttggcataa tctgctgcca gaattgacgg agcaatcttg tattgagaca taggtttctc
    36361 cttattttgg aatttttttg ctgacttttt tataggtttc tctacgattt tcaatttcac
    36421 taaggaattg caggtaatta tcaaaacgga aggttgcaat aacaccctct tcaacagctg
    36481 gtttgacggc acaagacggc tcatgggtat gggtacaagt acggaactta caatctcggc
    36541 taacagtagc aatctctggg aaagcctgat tgaggtcttc agcccttgat acttcatagt
    36601 ccaaggatga aaatcctggt gtatctgcga ttttaccccc gttgagattg taaaaactaa
    36661 cagctcgagt ggtatggcga ccgcgaccta gactgtctga aatttctccc gtttcaagat
    36721 tgaggtctgg tgcgagttta ttgagaagag ttgacttccc aacacctgtc tgccccataa
    36781 agaccgtaac cttgcctgtt aacaaagaca ggagttcctc tttactggtc acaaagtcat
    36841 agccgatgtc accataggtc tgccggtaaa aatccagttc tcccctatct tccaacaaat
    36901 ccattttgga aatatagaca atgggatgga tgcccttgtg ctccaaaaga accaagaaac
    36961 gatccagcaa attgctgtta aaatcaggtt ccttgacgga catgattact acagcttgat
    37021 cgatattgac aataggcgga cgaaccagac tgtttttccg ttcgtgaatt tttaggatat
    37081 agccttctga attttcctcg gcagagaaat ctacccagtc cccaacataa ggggtatggc
    37141 cttttttacg gaaattccca cgcgcgcgtg tttgataaac ctggccatca ctctccacat
    37201 agtagaaacc tgccaaggct ttaatgattt gtccctgcat cttagagtcc ttgcccttta
    37261 agtgcgtctg ctagaccggc aaattctgcc aagctgagag cttccccacg cacacttggt
    37321 gacaagcctg cctggttcaa agccttggtc agcttgtcct tgacctcttc agtcttacca
    37381 aagtaacctg tcaagttatt ccacaaggtc ttacggcgat ggataaaact agccttggaa
    37441 accttaaaga agaagttctc atcttccact gctacagctg gctctggacg gcgcaccatt
    37501 ttcaagatgg ctgaatccac atttggcgct ggcacaaaga ccgtacgagg cacgataaag
    37561 gcaaccttgg ctgtcatgta atactgcacg gcgatagaca agctaccgta agccttggtg
    37621 ttaggctggg ctgaaatgcg gtccgctact tctttctgca tcatgaccac aaactcacta
    37681 aaaggaatgc cactctcaat caagtgcatg agaataggcg tcgtgatgta gtaaggcaaa
    37741 ttagccacta ccttgattgg caggttagga tttttaaaat tttggatatg ttgcgccaaa
    37801 tcaaccttga gaatatcttc gttaactacg gtcacattat caaaatcacg cagagtatct
    37861 gccaaaattg gcaccaaacg gtggtcaatc tcaaaagcca tgacttgggc tgcacgctca
    37921 gccaaaaatt ctgtcaaggc accaatacct ggcccgattt cgatgacatt gacctgatca
    37981 tcaatttcag ccgtatccac aattttttga aggatattgg tatccgtcaa gaaattttgc
    38041 ccaaaggact ttttaaaggt aaaaccgtga cgctccaaca ctgccttggt cacgctataa
    38101 tctgcaattc tcatctattc tcttttctat tatctgttac tactattgta acacattccc
    38161 cttgtatttt gggaatgaaa atcataccaa aaaactatct ttcctcatga agaaagatag
    38221 tcttggaaat ctttaaagag ggacttagcg cttctctcga aacatacgtt catactcttc
    38281 gaaaatctct tcaaaccacg tcagcttcac cttgccgtac tcaagtacag cctgcggcta
    38341 gcttcctagt ttgctctttg attttcattg agtatcaaaa aaatcagctt cttgataact
    38401 tcgattttcg ggtagggtca aatccacatc ctcctccaca tcatccactg tcagttcaac
    38461 cgtttgaggt aaatttttca aacgataatg cttttgcctt tacccttcaa tactagcaaa
    38521 atcaagcaaa tagccatgca ctcggatttg aaccaaaagg agatgattgg tcatattttc
    38581 catgatgagg atatcttcta aaccacctct gacactagga taatcagata ccctgcgaat
    38641 acggattttt tcacacatga gcaagtttcc tcatatcaat gatttcatca gccttattcc
    38701 agactagggg attatgggtc gcaatgatga taattcgatt ttcatctttc aaatccacca
    38761 agagattcat aacctcctct gaattttcag gatcaagagc tgctgttggt tcatctgcca
    38821 aaatcaaggg tggatttttc aaaatagtct tagcaagggc aactcgttgg gcctctcctc
    38881 cagataaagt atagattttt tgttctaaat ccaaataccc tagattaact ttttctaaag
    38941 cccccacttg cctttccaaa cgttctactt ttgagatttt ctgaccaaca aaacccaaat
    39001 ccaaattttc tttgattgat tggttttcta agaggccgaa attttgaaag agatagccca
    39061 tctggtctcg aaaatactca cgagtgggaa tggtttttaa atctttcccc tgatagagaa
    39121 cccttccacc atctatcttt tctagctttc ccaagatatt cagcagcgtc gtctttccgc
    39181 ttccactctt tccgattaag gcataaacct tgcccttctc cagcttgaga ttcaaaccag
    39241 agaaaatcgc gcggtcatta aatttctttt ccaatccttg aatatcaatc atcttatttt
    39301 cctttcaata ctgccatgct accagcttct tcttttttgt cctgccttac taaaatcaag
    39361 agggcgttaa gcgtaaacaa agctacaact agagcgctaa tcaaaccatc tcttgtcaaa
    39421 atactagata ggactaggcc aagcaagaga actcctcctt gcgccagtaa atacttgcca
    39481 tgaagctcat agattgtcat accagcaaga cgtttaatca taagctcccg tctgaactgc
    39541 tcaaaataga gaagattcat ggaatcaaat aacaagatag ccgtagacag ggtcaaaatc
    39601 gtcccaataa ggagagagta aaactccacc cgtttgtcat ttagtacctt ggcaaaaaat
    39661 agctggcttt ttaccaagta agaaaccttg tgatacagac cttgctcttt tagagctgtg
    39721 atgctgtctc catatcgatc tagtttcaag gcactattag ccgtagttcc ccacaacatc
    39781 cctgcaacag gtcttgttcc agtcgcttgc ggcgttagaa ctacaataat cggatctttt
    39841 aggtactggc gtgttgtctt gtacccatca ttatagagga aacgttcctg tcctgtttct
    39901 gtaaaagcta gccttacctg tgggaggtag tgtttctgac tcgtcacttc tacactttca
    39961 gatgaaaagt tttgcaggta atctgtaaac aatccttggt agtagacaga ctgctctcgc
    40021 aagctctcag gcaagatcag cccaaactct ccctcagaca agttttgcat cttgtccata
    40081 aactctgaag aaacggtaat cttttcttct atcagatagc gtggtgagac atagataaca
    40141 ttccctgacg gtgtgtagtc actgagacga ttgccatcta ggtccacttc tgctccatct
    40201 gagaaattgt caacattgct cataatataa aaagagtctg tattggctaa ccgttcttca
    40261 gtaaatgtct gccactcacg attatcctta cgcgttcctt cttcatcggc aaatgcacta
    40321 gaccaaccaa aggatagacg gtaacggtct gaggactggc tccatttatt gctagctctc
    40381 tccatttcct gcatttcacg gtagtggggt aggagagctg tcgcactcga tccgaccacc
    40441 aatacagcta agagttgccc caccatcatc aatgtcatca tacgtttgag agggagtttc
    40501 cctttcaata gatccaccag actattttcc tgtaaaccaa gtagatagac gacacttagt
    40561 aaggtagaaa tccctgccaa ggtcaatcca taaagtagaa gagcaatgat gaccagttgc
    40621 accgttgcca taaacaaggc accttgatac cagagaatcc ccaatcccaa aagactggat
    40681 accagcactg agcagataag ctgtctcaca tcttctaaca ctggtctgag agcaactcca
    40741 aacaagctct caccagctat taagcgaatc cctgcctgac gaagggattt gatccgataa
    40801 atcagggtca gactcataaa ggtcagcaga aaaatagcta aactcagtag caccataggg
    40861 gtggccgtca atagtaagac tatcgaaaat ggatcttctc cattcgaaac aaagccttga
    40921 taaccaagct ctttcaaggt ggtctgtaag ctcactccat ccaaacttcc tgatacaatc
    40981 aagtaagacc ctaataaatc actcgtttct gcactctcct tggaggaaat ggtcagacct
    41041 tctggaagct ttccctcacc ataagtggca taggtaaagc gtgtttctcc agcttcattt
    41101 ggctcaacga ttcgacgagc aatgagacta ttgtgctcta ccgccaagtg actcaaagcc
    41161 tctgtcacct cttcgcgact agctactggt tgatttgtca tcattcctgt cacatcaaca
    41221 gaaggatagt taccaaataa aatctcttct cgatggtcaa cggaagttat caccatataa
    41281 agcgatacta ataccattga aatcaaaata aataaacgtt tcatcatttc ctccaaaaag
    41341 ttacttggtc acttagtgag aaggtgacca agtaaagcta aacaataggg ctataccatt
    41401 ctaaacatta tagtagaatg caactttctc tccccaagaa gtacgaatcc atgcacgaga
    41461 agtccctcca gcaccagcat atcccttgtc agatgaacca gtttttctgc taacaactgt
    41521 tgaactatgg tattttgaag ggtgatagta gtttgagtaa gcaccaccgt tacctgaacc
    41581 ataagtccaa acaccacctt ctgggtattg aacggctgca gaggcaactg ctacacttcc
    41641 acctaatgtt gctgcaatgc tcgctacaag agctaatttt ttaactgttt gtttcatatt
    41701 gatactcctc tatttttgat tacaagattg ttgagttact tgctcctctt tccattatca
    41761 acgttgatac tattatatta ccaaatgata ttctaaaatt atttgttttt ctctaaattg
    41821 tcaaaatagc accctgaaat gaacttttat agtcattata ctccatcttt atcacactat
    41881 caaggacatc aatgtcctta aaatctaact atttcatatt atttttagct tatatctaaa
    41941 aaaacagttc taaagacgaa ctttagaact gttttgatac gaggacaagg acatttttgt
    42001 cactgattca ctatgtttat aaatattttt ttaaatcttc ttgccattgt ttttctaaca
    42061 tagtaactaa ataagaattt tctattatat cagcaaatag cttcgatttc tgatagaact
    42121 gttcggcaga aacataatca ttgtttatta ttagagataa tttccactcc aacattaata
    42181 taattggttt cttctggaaa tcttgtgttt tttccattat atgattaagg ctaaagatat
    42241 aagctcctag tgaatcataa gacgacaaat tatccaaaca ggctagaccc gaaaacaaag
    42301 tgttacttaa agcaaacaga tattctggtg caattaattc tacatgattt gtcaaacgaa
    42361 ctaaaaacga atgaattctg ttaatttctt caatctgatt ttgaccttgt tttatctttg
    42421 taagcactat agcaaaatat aagttgataa cttctaattc atttatcaaa aacaattcct
    42481 tatcataaat tgttttaaaa taatcgtcca gtacggtttc cccgtattct ggttgtccgc
    42541 ttcgaataac atctatcgtt gctctagtag cttcaaacca tactttctcc tcattaggaa
    42601 gttgctcata aaataaatcc tctatctctt ccaaacacgc ttctttctta tcatactcct
    42661 cttctttatc atagattggt tcacgtaaaa tctggtattt caattctaaa taagcagaag
    42721 gaagagctga aaaatccggc ataaggctat aaactggaac tcctagccgg cgagcaatat
    42781 agtctaactt gggcaaactc ggttgcgaag ctccactttc aattcgcgac agttgacgaa
    42841 ctgtcagttc ttgctcatct ccacaaaaat ctggacgact aattcctttt tctatccgaa
    42901 tctctttaat tttttgacca attaacatca gacgcctcct cttctacctg cttcgaaaaa
    42961 tactgtgaaa cttaaaaaat tgtaacggct acatctttcc tactcataag atttcatagc
    43021 ttcttccact tctgccaaag taaccccaaa caactctagg cgtttgagga gttgcttgcc
    43081 gttagaatag ccgattcgga gagtctctcc gagatattct ctacgcttac ggctgtctgc
    43141 ccctgctaga aaaccaaggc gaatcaaatc gctacgacta atgtcaaact gactctcatg
    43201 ttcaaattgt tctgtcacct gagctagagc cgttttcagg tcttcatagc tggcatgctc
    43261 aattcccaga gaacgcccct tggtcttgga cttgggaaca gcttcatctc gcttgagaaa
    43321 ggcatgctga actgttggaa tggccgtcat aatcatgcgc cgaatccgct ccccattaaa
    43381 atctgggtct gtaaagacaa tgactccatg acgttggtgt agacgctgaa ttcgctctat
    43441 atcctgatca ttgatggcag aacctcgtgt ctcataggtc tccacatcga aataacgctt
    43501 gagattgacc gtatcatcgc gaccttcaac cacgataact tgagaaattt tctctttcat
    43561 tacttgctgt ccaatccaaa aattcgttct gcatttgcag tcgttgctac cgccagctct
    43621 tctgtcgtca taccacgcaa gtcagcgata aagtcgacca catagcgagt ataggctgtt
    43681 ttattttcac gaccacgctt gggtacaggt gctaagtaag gcgcatctgt ttccaccaac
    43741 atcttgtcca aaggtaactc tttagctgct tcttggaggt cagttgcctt cttgaaagtc
    43801 accactcctg agaaggaaat ggtcatacca agatccacaa acttctctgc ccactcaagc
    43861 gtccctgaaa atgaatgcat gataccacca cgaggaccaa cgccctcact cttgataatc
    43921 tcataggtat cttccagcgc atcacgggta tggacaacaa aaggcaaatc caagtcctta
    43981 gatagctgaa tctgacggcg aaaaacctgc tcctgcacct ctttgggcgc tgtcatccaa
    44041 tggtagtcta agccaatttc acctaaagcc acaaccttgg gatgttttaa cttatccaac
    44101 aagtaagcct caacttcctc tgtataagta ccagcttctg taggatgcca accaatagtc
    44161 gcatagagct gctcatactc atctaccaac tccaaggcac gctcaatcgt cggtttatca
    44221 aaaccaacaa tattcatctg tgtcacaccc atctcatcag ccaaggcaat ttcttctgcc
    44281 tcacgacctg caaattcttc tacattcaag tgtgtatgtg tatcaaaaat catctcttct
    44341 aacctcgttt tctatcttct attataccaa aaaagaggag gggcacctaa tttttcggtt
    44401 tcccctcctc tcttcaatag agagctattc tgctatcttt tctatccgat attgcccatc
    44461 tcctattcca cagttagaga cagaagagat tggctacatt gatagaatat tcctattcag
    44521 ctaaagtatg tgattatctt gggttctcac ttttctcacc catcactagg attgatgact
    44581 tctcaaaatc ccccttataa tctaacttta agtagagaat agaattttct agctgttcta
    44641 ttttctacgt ctagtctttc ttcctagcaa agcaaaacca cttgttgcca ccactagacc
    44701 aagactagca agtgctgcac ttgatgctga acctgtgtta ggtaattgtt tgccagcagg
    44761 tgactggtag gtaacatctt gcattgttcc tgcagttgct tgcggtgcac ttgttgtctt
    44821 aggagccact ggtctcttag gaactgtaac catggcaatg gcttgcactc caatcgtttc
    44881 tgcttccttc acatcttcca tagttttcgc attttcaatc tctttgagag ctgcttgttt
    44941 ttctgcttcc actcttgcta aaagttctgc tttttcttta tcagaaagcg gtgcgccttt
    45001 gatttcatcc tgcttgtcct tggctgcttt ttcaatggca tttttagctg attctttttc
    45061 agtagctaat tgcttagaag cttgtgattg agctgagttt tgtgaacctg tgtgagctgg
    45121 tccacctgcc tggctaccac cgcctgcatt cgcattagca tctgagtttc cagtattgcc
    45181 tcccttatct ccacctggtg tagtttctgg cttatactct ggtgtagctt cttgagttac
    45241 agattcacct ttcgcagatt gttgaactgt atcttttcct agaatcgtca ctactgaacc
    45301 atctgggaat gtgattgttg ctgtgccatc tccagctact tcaactttat agtaaaataa
    45361 aataataaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa
    45421 cagaggtgta ctattctagt ttcaatctac tataacatcg cttccgaatc catttgcatc
    45481 tactgaactt ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata
    45541 gaattcgttt ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata
    45601 cgcgacgacc atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa
    45661 gtttacttgg ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt
    45721 ttagccggct ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc
    45781 acttttgtca atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac
    45841 gatactgttt caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag
    45901 gaaggtaaac gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca
    45961 agagaacctt ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt
    46021 acatattgcg gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca
    46081 aacctggaat atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac
    46141 caggaagaag caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt
    46201 gggccaaaac gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc
    46261 ccttaacatg agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc
    46321 ggtgggattt tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca
    46381 caggcgtatg cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa
    46441 tcaaatcgtt ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg
    46501 ctccagttgg gttatttgga ttgataagga caattgcctt ggtattggaa gtgatttttg
    46561 acttgatatc gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg
    46621 catttcctcc agctaggctg acagccgccg tccatagagg atagtctggc attggcacta
    46681 agacctcatc cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac
    46741 catttccaag gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact
    46801 gcatgatggc cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac
    46861 gtgcattcat aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg
    46921 gatttcctgt attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt
    46981 ccaatacagg accacggata tcataagcaa catgctctaa cttactagac ttattatatt
    47041 ctttcatctt gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg
    47101 cgacaagttt actgaaatgt gttactagtt tcgtatagaa aaaaaacctt gctaaaagcg
    47161 aggttaagaa cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa
    47221 acctagaaaa agcaagccta gaaaggagtc ataaagaaga ttaaacatga ggaaaagccc
    47281 ccatatcatc aagtaatccc aacgcccact tcgttttgca actagaaata agattagatg
    47341 gtagagtaca tgaaagacta aaaatccaat aaaacctgga taaagaagcg gtaccagact
    47401 ctctaattgc cagatcatga tcacttctac caagactgaa actaggataa ttccataata
    47461 caggaaattt gatttttgaa aagagttttt catcattctc ccttccttca cttctttcct
    47521 gctatccttt cttttatttt atcatatatt tatatagatt ttaagcccta atattctttt
    47581 gaaaaatact ttttttgctt tacttctata gtgaaaaggt ttacaattat agtaagaaaa
    47641 ttgcaggagg tttcattatg gcacaacgtt accaaaatat catggtcgca atcgatggtt
    47701 ctaaggaagc ggacttggct tttgtcaagg gagttcattc tgctctacga aacgacgcta
    47761 aactcaccat cgcacatgtc attgacacac gcgctctcca aagcgtatcc acctttgatg
    47821 ctgaagttta cgaagaactc caagtcgacg ctgaaagtct gatgaaagag tacgaaaaac
    47881 gtgctaaaga tgctggggta gcagatgttc atatcgtcat tgaaatggga aatccaaaga
    47941 ccctgctagc acgtactatt ccagatgccg aggaagtgga cctcatcctc gttggcgcaa
    48001 ctggtctcaa cgcctttgaa cgcctcttgg tcggctcttc atctgaatac atactccgcc
    48061 atgctaaggt cgatttgctg gttgtgagag aacaagaaaa aaccttataa tcacaaagaa
    48121 aaggagcccc tagctccttt ttgtttacga tttatttctc tctttatggc gttcgtaagc
    48181 cttgagctgg cgctgcagtt cctttttaat agcaggttct ggagcatatt tttcttccca
    48241 attatctggt tttaagattt tatgggtcac tggatcaaaa tgagccttac catctggaaa
    48301 aattttcccc atattggcct gatggacaat atcaaaaata cgttctgggt ccacccccat
    48361 caagacaaaa ctgccgtagg tgaagtaaag cgtgtcaatc aaggcatcca cttgccctat
    48421 caaatcttgc tgagcaggtg tcttcttggc tactttacct gctgccttat caagggcctg
    48481 atgaagttgc gatacagctt gaccaaaatc ttcttcagaa ggactggctg atcgaacaaa
    48541 ctccaccaat tcttctattt taaaaccagc cctatgggtt gcaccctcta aatcccaagc
    48601 tcgaggttct tcttgggttc gttcatccat catgtggtgg aaggtcttga ccttattgaa
    48661 atgatagtca cggctgacaa agactttttc tgaagacaaa acaccaaaat gttccaaggc
    48721 cttgtggatc ccatcttgtt gattgctagt ggtaatgtgc ttggcagctt ccttgacact
    48781 gctactacca tttcccatag cgaccgacat accgacgcca gccagcattt caaggtcatt
    48841 atctgagtca ccaaaagcca tgacttggtt gaggtcaaag ccatattctt tcccaactcg
    48901 gcgaatgcct tctaatttag aatttccctg attgatgaca tccgatgcaa aaggattgct
    48961 acgtgtcaat ttcaagtctt caaaatcagc tgccgccttc tcagattctt ctggtgtcat
    49021 cagcatcaaa acttggtaga taggctgatt catcaggtga agcaggtcct cttccttttg
    49081 gggaacaacc ttgctgacca tgcgattaaa agactgactc accgtccgag ttaaaacaga
    49141 gggaacgaag cgactaattc gttgggaaaa agaacccaga ccaaaggaca tgattttaga
    49201 acccaacatg gcatccttgg tccctagagc aatctccgtg ccctcttttt tagcatagct
    49261 aattagatgg cgcaaatgta acttggaaat agggctcgtg aacaagactc tgtctttact
    49321 aaagatatac tggccattat aggttaccgc aaaatccaga tccaaatcgt ccatcaattc
    49381 cttaacaaaa aaaggtcctc gccctgtcgc tacgccaact agtacccctt gttctttgac
    49441 aatcttaatc gcgtccttag tggatttcaa aacactcttg cgattgttga ccaaggttcc
    49501 atcgatatca aaaaaaacag ctttgacttc catcctattc caatctcccc ttttgtgata
    49561 caatgattat accacatttc agaaagagtt agtaaatcat gcctaagaaa atccttgttt
    49621 tacatacggg tggaactatt tccatgcagg ccgatgcttc tggcgctgtt gtgacgagtt
    49681 cagataatcc catgaaccat gtgtccaacc cacttgaagg aatccaagtc cacgccttgg
    49741 acttttttaa ccttccaagt ccccatatca aacccaaaca tatgctggtc ctctaccaga
    49801 aaattaaaga ggaagcagat aactacgatg gagtggtgat cacacacgga accgatactt
    49861 tagaggaaac agcctatttc cttgatacca tggaagttcc ccatatgcct atcgttctaa
    49921 caggagccat gcgtagctcc aatgagctcg gtagtgatgg tgtttataat tacctaagtg
    49981 ctttacgagt ggccagcgat gacagggctg ctgacaaagg agttttggtc gttatgaacg
    50041 atgaaatcca cgctgccaag tatgtcacca aaacacatac gactaatgtc agcaccttcc
    50101 agactccaac acatggcccc ctcggtctca tcatgaaaca ggaaatcctc tacttcaaaa
    50161 cagctgaacc tcgtgttcgc tttgaccttg aacacataca aggtttagtc cctatcatct
    50221 cggcttatgc tggtatgaca gatgagctga ttgatatgct ggatttagaa cacttggacg
    50281 gtttgattat ccaagccttc ggagctggta atattcccaa agaaacggct caaaaattag
    50341 aaagccttct gcaaaaagga atcccagtcg ctctggtatc acgatgcttt aacggtattg
    50401 ccgagcctgt ttatgcctac cagggtgggg gcgtacagtt gcaaaaagca ggcgttttct
    50461 ttgttaaaga actcaacgcc caaaaagccc gcttgaaact cctcatcgcc ctcaatgccg
    50521 gactaacagg acaggctttg aaagactata tggaaggcta atactcttcg aaaatctctg
    50581 caaaccacgt cacgtcgcct taccgtatgt atggttactg acttcgtcag tttcatccac
    50641 aacctcaaaa acatgttttg agctgacttc gtcagtttca tctgcaacct caaagcagtg
    50701 ct
//
LOCUS       DBEJJE010000009        46897 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEJJE010000009 DBEJJE010000000
VERSION     DBEJJE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.09"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..297)
                     /locus_tag="ACL3F5_000528"
     CDS             complement(1..297)
                     /locus_tag="ACL3F5_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514381.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            complement(281..2407)
                     /gene="pfbA"
                     /locus_tag="ACL3F5_000529"
     CDS             complement(281..2407)
                     /gene="pfbA"
                     /locus_tag="ACL3F5_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0514382.1"
                     /translation="MKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILADEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNS
                     SKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKI
                     MELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="ACL3F5_000530"
     CDS             complement(3571..4797)
                     /locus_tag="ACL3F5_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0514383.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="ACL3F5_000531"
     CDS             complement(4840..5532)
                     /locus_tag="ACL3F5_000531"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0514384.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="ACL3F5_000532"
     CDS             complement(5705..7456)
                     /locus_tag="ACL3F5_000532"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514385.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7446..9191)
                     /locus_tag="ACL3F5_000533"
     CDS             complement(7446..9191)
                     /locus_tag="ACL3F5_000533"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514386.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9319..9849)
                     /locus_tag="ACL3F5_000534"
     CDS             complement(9319..9849)
                     /locus_tag="ACL3F5_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0514387.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKGAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(9846..10302)
                     /locus_tag="ACL3F5_000535"
                     /pseudo
     CDS             complement(9846..10302)
                     /locus_tag="ACL3F5_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10436..11263
                     /locus_tag="ACL3F5_000536"
     CDS             10436..11263
                     /locus_tag="ACL3F5_000536"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0514388.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11275..11370
                     /locus_tag="ACL3F5_000537"
                     /pseudo
     CDS             11275..11370
                     /locus_tag="ACL3F5_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            11418..11657
                     /locus_tag="ACL3F5_000538"
     CDS             11418..11657
                     /locus_tag="ACL3F5_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR0514389.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12040..12135
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12535..13116
                     /locus_tag="ACL3F5_000539"
     CDS             12535..13116
                     /locus_tag="ACL3F5_000539"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0514390.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13116..14378
                     /locus_tag="ACL3F5_000540"
     CDS             13116..14378
                     /locus_tag="ACL3F5_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0514391.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14429..14890)
                     /locus_tag="ACL3F5_000541"
     CDS             complement(14429..14890)
                     /locus_tag="ACL3F5_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR0514392.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14887..15651)
                     /locus_tag="ACL3F5_000542"
     CDS             complement(14887..15651)
                     /locus_tag="ACL3F5_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR0514393.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15832..16236)
                     /locus_tag="ACL3F5_000543"
     CDS             complement(15832..16236)
                     /locus_tag="ACL3F5_000543"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0514394.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16306..17787)
                     /locus_tag="ACL3F5_000544"
     CDS             complement(16306..17787)
                     /locus_tag="ACL3F5_000544"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0514395.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLSRVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(17806..18984)
                     /locus_tag="ACL3F5_000545"
     CDS             complement(17806..18984)
                     /locus_tag="ACL3F5_000545"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0514396.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELNEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19149..20156
                     /gene="galR"
                     /locus_tag="ACL3F5_000546"
     CDS             19149..20156
                     /gene="galR"
                     /locus_tag="ACL3F5_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0514397.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20202..21239)
                     /locus_tag="ACL3F5_000547"
     CDS             complement(20202..21239)
                     /locus_tag="ACL3F5_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR0514398.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKVVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21240..21593)
                     /gene="nmlR"
                     /locus_tag="ACL3F5_000548"
     CDS             complement(21240..21593)
                     /gene="nmlR"
                     /locus_tag="ACL3F5_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0514399.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21837..22727)
                     /gene="czcD"
                     /locus_tag="ACL3F5_000549"
     CDS             complement(21837..22727)
                     /gene="czcD"
                     /locus_tag="ACL3F5_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0514400.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22860..23396
                     /gene="sczA"
                     /locus_tag="ACL3F5_000550"
     CDS             22860..23396
                     /gene="sczA"
                     /locus_tag="ACL3F5_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR0514401.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23563..24369)
                     /gene="pnuC"
                     /locus_tag="ACL3F5_000551"
     CDS             complement(23563..24369)
                     /gene="pnuC"
                     /locus_tag="ACL3F5_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0514402.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSETMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24714..26234)
                     /locus_tag="ACL3F5_000552"
     CDS             complement(24714..26234)
                     /locus_tag="ACL3F5_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0514403.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26227..26955)
                     /locus_tag="ACL3F5_000553"
     CDS             complement(26227..26955)
                     /locus_tag="ACL3F5_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0514404.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(26970..27734)
                     /locus_tag="ACL3F5_000554"
     CDS             complement(26970..27734)
                     /locus_tag="ACL3F5_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0514405.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27738..28181)
                     /locus_tag="ACL3F5_000555"
     CDS             complement(27738..28181)
                     /locus_tag="ACL3F5_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0514406.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28863..29159)
                     /locus_tag="ACL3F5_000556"
     CDS             complement(28863..29159)
                     /locus_tag="ACL3F5_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0514407.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29181..30245)
                     /gene="pepA"
                     /locus_tag="ACL3F5_000557"
     CDS             complement(29181..30245)
                     /gene="pepA"
                     /locus_tag="ACL3F5_000557"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0514408.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30646..31347
                     /gene="galE"
                     /locus_tag="ACL3F5_000558"
     CDS             30646..31347
                     /gene="galE"
                     /locus_tag="ACL3F5_000558"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0514409.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31363..31473
                     /locus_tag="ACL3F5_000559"
     CDS             31363..31473
                     /locus_tag="ACL3F5_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0514410.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            31770..32729
                     /locus_tag="ACL3F5_000560"
     CDS             31770..32729
                     /locus_tag="ACL3F5_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514411.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32719..33675
                     /locus_tag="ACL3F5_000561"
     CDS             32719..33675
                     /locus_tag="ACL3F5_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0514412.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33672..34424
                     /locus_tag="ACL3F5_000562"
     CDS             33672..34424
                     /locus_tag="ACL3F5_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514413.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            34520..35485
                     /locus_tag="ACL3F5_000563"
     CDS             34520..35485
                     /locus_tag="ACL3F5_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0514414.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDTQKALK"
     gene            complement(35710..35952)
                     /gene="yidD"
                     /locus_tag="ACL3F5_000564"
     CDS             complement(35710..35952)
                     /gene="yidD"
                     /locus_tag="ACL3F5_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0514415.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35952..36674)
                     /locus_tag="ACL3F5_000565"
     CDS             complement(35952..36674)
                     /locus_tag="ACL3F5_000565"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0514416.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVTNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36661..37230)
                     /gene="scpB"
                     /locus_tag="ACL3F5_000566"
     CDS             complement(36661..37230)
                     /gene="scpB"
                     /locus_tag="ACL3F5_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0514417.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37249..37977)
                     /locus_tag="ACL3F5_000567"
     CDS             complement(37249..37977)
                     /locus_tag="ACL3F5_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0514418.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37977..38711)
                     /gene="xerD"
                     /locus_tag="ACL3F5_000568"
     CDS             complement(37977..38711)
                     /gene="xerD"
                     /locus_tag="ACL3F5_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0514419.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38708..39169)
                     /gene="cbpB"
                     /locus_tag="ACL3F5_000569"
     CDS             complement(38708..39169)
                     /gene="cbpB"
                     /locus_tag="ACL3F5_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0514420.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39166..39687)
                     /locus_tag="ACL3F5_000570"
     CDS             complement(39166..39687)
                     /locus_tag="ACL3F5_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0514421.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39663..40634)
                     /locus_tag="ACL3F5_000571"
     CDS             complement(39663..40634)
                     /locus_tag="ACL3F5_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0514422.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40631..41425)
                     /gene="racE"
                     /locus_tag="ACL3F5_000572"
     CDS             complement(40631..41425)
                     /gene="racE"
                     /locus_tag="ACL3F5_000572"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0514423.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTRQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRKKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41632..41880)
                     /locus_tag="ACL3F5_000573"
     CDS             complement(41632..41880)
                     /locus_tag="ACL3F5_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0514424.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42136..43761)
                     /gene="treC"
                     /locus_tag="ACL3F5_000574"
     CDS             complement(42136..43761)
                     /gene="treC"
                     /locus_tag="ACL3F5_000574"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0514425.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43939..45906)
                     /gene="treP"
                     /locus_tag="ACL3F5_000575"
     CDS             complement(43939..45906)
                     /gene="treP"
                     /locus_tag="ACL3F5_000575"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0514426.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTVTIPGTYPTTIQAGASLMVATRI"
     gene            46091..46801
                     /gene="treR"
                     /locus_tag="ACL3F5_000576"
     CDS             46091..46801
                     /gene="treR"
                     /locus_tag="ACL3F5_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0514427.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13705 a        10662 c         8788 g        13742 t
ORIGIN      
        1 ttatttcatt ttactatact ctgttaattt atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttaccc ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactgtt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gctaaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta ttttttaaca attgattatt acttttctta
     2461 aaatagatag agtgacaccg ctgtcattat ctttatcata tattttccaa attgaattgt
     2521 caaggaataa cacaagaaaa tattaaaatt tatactcttc ggaaatctct tcaaactagg
     2581 tcagtgccgc cttgccctaa gtctaggtta ctgacttggt cagttctata gtagactgaa
     2641 actataatag tacacctcta cttctaaaac attgttagaa atcgatttaa ctgtcccgat
     2701 caatttgtcc tattcttatt tcattttact atatctacaa cctcaaagca gggttttgag
     2761 ctatctatgg ccaacttcct agtttgctct ttagccttcc attcaaaagt gatgctatct
     2821 ttcttagctt gaatataaaa tatcccattt actatattta aatttattga tatgttgtaa
     2881 attataaatg aaagaacaaa taccttgtca tacaagcatt cgccagggat atttacctga
     2941 atatcgctca tatggcggat tgaaactaaa acactacaat atatttctta aatagacctt
     3001 ctataaaagc tagatttaac ctcgataaaa atagatgcag tgcttctaaa atactggaat
     3061 agggcatata ggtaatcgta gacaagtgtt ttatagattg tctcgcagga gatctaatga
     3121 tgtatagcaa gcatcactaa acatatggga tattcgtatt attataatat caacatgcta
     3181 taaattctat catgcaaaag aatgactaga acatgaaaga caggcacaaa actttgaaca
     3241 atattctgaa aacaaaaaaa gacgcgagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct acaccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 acaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaacctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaacggca tggaatgaga aggaagtaaa atcagcgata gaaccagaag gttgtccttt
     4261 ataagtagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactgggata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc
     4741 agcaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgatga tggtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aattcctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tacggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacggaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 cttactatcc aacttgatcc aaatgctcaa gatgagaaag atgggagagg ttagaaccag
     5401 taagaccaag gccaaaaacc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtataggcc atggcccctg cctgcaaact atacatcttg tgataggttc
     5761 ctcccagagt caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcgtct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaaact ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actgatttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgtaaaacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatac gagaaacaca
     6421 catgttcaaa acggatattg ccttctttga ctttggcttg cccattttct tgaaggggct
     6481 cataggtcct ctcatcgatt aaggcaaaga cacggcctgc agaaaccata gacgtttgca
     6541 gtgttgaaaa gttttgcgtc acctcaatca aagggtcaaa gaggcggttg atgtactgga
     6601 taaaagcata catggtcccg gccgttatcc cgatagaaag accacgatag ccaaaatagg
     6661 ccatcaagac agcataacct agaagtttca acaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcataga ccaagtgctc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaagg cctggattat tctgattccc tcgatgtttt
     6841 cagccagctt gctattgata tctgacaaga gacttctggt tttctcaatg attttcactg
     6901 attttttccg atagagattg accaaaagga aaatcaaggg gagaaagagc aagactaatg
     6961 ctgtcaaacg aaaatccaat accaacatgg tataaagagt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctagataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgtgcaa
     7201 agagaagatt gccgacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacaagggg aatgacactt ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtaaggag tccataaggc ttgagatagg acatcaagcg cttcaataca gtccattgtt
     7441 cttgtttatt ctgcatcttc ttctcccttc atttccagct gctgagactg gtaggtttgg
     7501 gcataccagc catccaaagc tagcaagtct tcgtgcctgc ctcgttcgat aatttgacca
     7561 ttttgcagga ctaaaatcaa atctgcatgg acaactgcac tcaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa aaagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatgg cgcccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactcc
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccaccaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gcataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga tgtgatggca
     9061 tcaataaccc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaattc cgactagata acggcgtttt tctaacttga aaaaccacca aagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agagattttc gaagagtaca agaccccagg tttttctttt tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca caacgataag
     9601 ttgcccattt tgctcttgca cagctccttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttctgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagccatt tgagagtcaa gaccagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaattcggt tcccttttta tcatggtatg ccttaaaagc
    10201 aaaaaaaact gtcacagcta atagaacaat cccaaagcca accatgatac cattttgctg
    10261 accgatttgg ctgagtacat agtcataaga gtagaatttc atatattttc actccctttc
    10321 ataaaatcat tcttaattat aaacgaaaga gagtaatttt tcaaaccata cgttggggaa
    10381 atagatcttt ttttggtata ataaaatcta taatctgaat gaaaaaggta actttatgaa
    10441 acttatctca tggaatattg attccctaaa cgctgcccta actagtgact cagctcgtgc
    10501 caaattgtcc caagaagtcc tacaaacctt ggtcgctgaa aatgctgata tcattgctat
    10561 ccaagaaacc aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga
    10621 actcttccca ggctacgaaa acacatggcg ctcttcccaa gagcctgccc gtaaaggcta
    10681 tgctggaacc atgttccttt ataagaaaga acttacgcct acgatcagtt ttccagaaat
    10741 cggtgcccct tctaccatgg acttggaagg ccgtatcatc actctagaat ttgatgcatt
    10801 tttcgtaacc caagtttaca ctccaaacgc tggtgacggt ctcaaacgct tggaagaacg
    10861 ccaagtctgg gatgttaaat atgctgagta tttggctgaa ctagacaaag aaaaaccagt
    10921 ccttgcgacc ggtgactaca acgtagccca caatgaaatc gaccttgcaa atcctgctag
    10981 caaccgccgt tcacctggat ttactgacga ggaacgtgct ggatttacca accttttggc
    11041 aactggattt acagacacct tccgccatgt tcatggcgat gttcctgaac gctacacttg
    11101 gtgggcacaa cgcagcaaaa cttctaaaat caacaataca ggctggagaa tcgactactg
    11161 gctcacaagt aaccgtatcg ctgacaaggt cactaaatct gatatgattg actcaggtgc
    11221 tcgccaagac catacaccga ttgtcttgga aattgacttg taaggatttt ctatatggac
    11281 tacaatgcgg tcattcccga gtttcttgta tcgaatatcg aacagtcccg gtccttctac
    11341 tgtggtttac tgggttttag gattgaatac taacgtccag aagaaaactt tctctttctc
    11401 ttgaagagtg tcaactaatg ttagaggagg gaacaaagga tcaactagct gaactgacct
    11461 acccctttgg tcgtggagtc aatctctcct ttggcataaa ggatgttcca aaactctatc
    11521 aaaaagtgat ggaggcaaac tatcctattt atcgtctctt gaccaaaaga aagtttcgtg
    11581 tcagtgatcc ctatatctat cctcataaat ttgcagtttt ggatccagat ggctattttt
    11641 taagatttag cgagtagaat aataaaaatt gggaaaagtc tttaaagtta gaaaaaggca
    11701 tattgtcagg tgtctaaaaa cttgatagta tgccttttat gatggaaaaa tcttctaata
    11761 ctcttcgaaa atctcttcaa gccacgtcaa cgtcgcctta ccgtaggtat atgatactga
    11821 ctctgtcaat tctatccaca acctcaaaac agtgttttga ggttgtggat agcttcctag
    11881 tttgctcttt gattttcatt tagtataaat gttagcttac aatggagttt ttgttcaccc
    11941 tctcttcttt ttgttcgctt tttaaaccaa aacactaaca aaatagttga tttctaaagt
    12001 tatttagtgt aaaataaaaa cattggctca agcctattta aaattgaata tcgttttact
    12061 tgtttatgtc gtgaattggc acgacgtttc tacaaggtgc cggaacacct aacaataagt
    12121 aagtcagcag tgagatatgg ccgtttttgc catgtctatt taggggactt acttagagat
    12181 taagtaggtc ttttttgaat atttttaata tttcccttaa ttagtgcgga cgggaggtga
    12241 aattatcctg tgaataattt caggaatcca gggaatttca tccctaattt ttgagcccct
    12301 agctctttca tttctaggct taggctaaaa tagttccccg aactatttta ctctcaaaaa
    12361 tcccgtcata gacaataaca agattattgt ctatgatacc actacaacgg gaaatatttg
    12421 ataagactcg cttcgctcgt aatagtttta tcaaatatat agtattagca aaagggatca
    12481 ctatagaaat atttaaacaa caagtaaatt aacttttaga ctttaggagg tcttatgaaa
    12541 ttattagaag agcgcatcct caaggatggg catatcttgg gtgataacat cctcaaggta
    12601 gattcctttt taacccacca agttgacttt agcttgatgc gagagattgg taaggttttt
    12661 gcggaaaaat ttgctgctac tggcattacc aaggtcgtaa ccattgaagc gtcgggtatt
    12721 gccccagccg tttttacagc tgaagcctta aacgttccca tgattttcgc caaaaaagct
    12781 aagaacatca ccatgaacga aggcatctta actgctcaag tctactcctt taccaagcag
    12841 gtgaccagca ctgtttctat cgctggaaaa ttcctctcac cagaggacaa ggttttgatt
    12901 atcgacgatt tccttgctaa tggccaagct gctaaaggct tgattcaaat catcgaacag
    12961 gccggtgcca cagtccaagc tatcggtatc gtgattgaga aatccttcca agatggccgt
    13021 gatttgcttg aaaaagcagg ctaccctgtc ctatcacttg ctcgtttgga tcgttttgaa
    13081 aatggtcagg tcgtatttaa ggaggcagat ctctagtgca aactcaagaa aaacactcgc
    13141 aagcagccgt tctgggcttg cagcacttac tagccatgta ctcaggatct atcctggttc
    13201 ccatcatgat tgcgacagcc cttggctatt cagctgagca gttgacctac ctgatttcta
    13261 cagatatctt catgtgtggg gtggcaacct tcctccaact ccaactcaac aaatactttg
    13321 ggattggact cccagtcgtt cttggagttg cattccagtc ggtcgctccc ttgattatga
    13381 ttgggcaaag ccatggtagt ggcgctatgt ttggtgccct tatcgcatct gggatttacg
    13441 tggttcttgt ttcaggcatc ttctcaaaag tagccaatct cttcccatct atcgtaacag
    13501 gatctgttat taccacgatt ggtttaacct tgatccctgt cgctattgga aatatgggaa
    13561 ataacgttcc agagccaact ggtcaaagtc tcttgcttgc agctattact gttctgatta
    13621 tcctcttgat caacatcttt accaaaggat ttatcaagtc tatctctatt ttgattggtc
    13681 tggttgttgg aactgccatt gctgctacta tgggcttggt ggacttctct cctgttgcgg
    13741 tagctccact tgtccatgtc ccaactccac tctactttgg gatgccaacc tttgaaatct
    13801 catctattgt catgatgtgt attatcgcaa cggtgtctat ggttgagtca actggtgttt
    13861 atctagcctt gtctgatatc acaaaagatc cactcgacag cacgcgcctt cgcaacggtt
    13921 accgcgcaga aggtttggcc gtacttctcg gaggaatctt taacaccttc ccttacaccg
    13981 gattttcaca aaacgttggt ttggttaaat tgtcaggcat caaaaaacgc ctgccaatct
    14041 actacgcagc tggtttcctg gttctccttg gactgcttcc taagtttggt gcccttgccc
    14101 aaatcattcc aagctccgtc ctcggcggtg ccatgctggt gatgtttggt tttgtatcta
    14161 ttcaagggat gcaaatcctc gcccgagttg actttgctaa caatgaacac aacttcctta
    14221 tcgcagctgt ttcaatcgct gcaggtgtcg gtctcaacaa cagtaatctc tttgtcagca
    14281 tgccgacagc cttccaaatg ttcttctcaa acggaatcgt cgtagccagc ctactcgcca
    14341 ttgtcctcaa tgccgtatta aatcataaaa agaaataaaa aaaagaggtg cgagcctctt
    14401 ttttgtgtga caaaataaaa acatctacct attcatatat gctagtgtca tagtcctgaa
    14461 aatcatctgc atcaagaaca atttcacaac tcttatactt ttctcttaca agtcgttcgg
    14521 cttcatctgg attttcagcc tctatactta ctaaacgtga taaagtttct gtaatttcta
    14581 ctgtatactt tttcagtttt agattgcttt ccaataattc acctattaac aataatctat
    14641 gataggagct atgtagccac tctggcaatt tatctcctac ttcccaccca tatttttcct
    14701 tcatcaaagc tagttgtttt tcgtcaccaa atttcatatt ttcagataac catctcacac
    14761 aatcgggatc tgataaggta cagacgatta aacttaggtt atcgtaacgg ctttcagttt
    14821 cataatcagg ccagatgact tttaagaaat catacacctc ttctgatgca acaagttgtt
    14881 tcgttttcat aatttccgat actttcctct acctttaaat tctattattt ctttgtctct
    14941 taatatttga agctgttgcc taatcttttc tttgatatga ttgttcttaa caaagatatt
    15001 ttttaggtca ctttcaaaac gatacatatc ttcaagggta aattctgaac cctctatctt
    15061 atctatacaa tttagaattt ctattgtcca acctcttgat gacagagagc tcttccttaa
    15121 aaataaacct tgcttaaatt cttttgtaac tttttctgga tctctaactt gtccatcttg
    15181 cacaagaaat atccttcctt tagaaggtac ttgtgataaa tcaatgttac aaccaatcca
    15241 acctgctcgt ctagcagttg gtgcaagtgg ttttctttga ataatcgatt tcggtgtaac
    15301 aaattgcttc ggaaggacaa gaaagttatt tacctcaaaa ttttttgtgt aagttaaaaa
    15361 aaagaaatta ggattattat ctgcctgcac acgcttcatc atcgttgcat aagcaccatc
    15421 attgattgtt gatgaaaaat ttcctttttt gctctttagt tcaaactcct cactacaatg
    15481 attacagtaa aaatctgcta caggccgatt attttcaaaa tgatttaagg gattgttccc
    15541 acaattaggg caataagact gacgataaac ccaatcctcc gttaagatac gtgccttttg
    15601 gctattactt ttataagttt ctactaattc taaattaaag tgtaattcca tttaaaaatt
    15661 cctcactaat atgagaactc actcgatata agcaattaaa atctactata actagtatac
    15721 cacatatatg tacctattac atttgtattt catcactctc ttttatattt ccttctaaca
    15781 tatctcataa attaaaaatg agtgagataa atttatccca ctcacctttc tttatatact
    15841 tacccgtctt tcctcagacc tttggcctgt gacaaacatg gtaaaggttg ccttacagac
    15901 atttctgccc tcttgattgg tgatatccac atccatcaca caggttgtac gaccttgatg
    15961 gacacattct cctttaatgg tcaatacatc gtcgagtttt cctgccttaa ggtagttgat
    16021 agaggattgg agtgtcaccc catcaagtcc cagcgagata accaccaaac cactgatttg
    16081 gtcacatagc gtgaatagat agccaccatg ggcattgcca tagtagttga gcgatgagtt
    16141 cactactttg gtcgtcacca caacgtgacc atctctcatt ttttcaattt cgtaattttc
    16201 aaaggcagat atagcgtcaa aatgaaagtc tttcatcgtt tcctcctgat atttcaaacg
    16261 acactatgat actacttttt ataggactgt gcaaggagaa agctcctagt ctagtaaaat
    16321 tccgacctgt tccacaaagc gcataaaggc tgtctgccct tgttctgtct gcttgtagac
    16381 tcctgcatcc tcaagtacac gcacaaagat agcacccaca gagtccttga cgattgcaag
    16441 ggctttttct ttatccgtta ggtctggatg ttgggatttg agttggtctg cccactcctg
    16501 atgataatcg gcaactgtaa cagcttctcc tacaagatag ctagcgactt gctctacttc
    16561 ttctttcaga cgtggtggca agattgccaa gcccatgacc tcaatcaagc cgatattttc
    16621 cttcttgata tgttggacat ccttgtgggg atgatagatg ccatcaggat gctctgctga
    16681 agtctgattg tctcgcaaga ccaagtccaa ctcaaactgt ccatcacgct tacgcgctat
    16741 tggtgtgatg gtgtgatgcg gtgtcccgtc tgtctctgct aaaatctgca cactagaatc
    16801 tgaatactga cgccattcct ggaaaatctt atcagctaag ttaatcaaat cctctttgga
    16861 atccgaagtc aagcgtagga cagacattgg ccacttgata attccagcct tgacctgctc
    16921 aaaaccagca aatcggaagg tcttttgcaa gggagccaat tccataggaa atacgtgacg
    16981 gcctccctga taatgatcat gagttagaat agagcccccc acaatcggca ggtcggcatt
    17041 agatccagca aaatatcctg gaaactgctc tacgatagcc aacagacgtt caaaactctg
    17101 acgactaatg gccatgggac gatgctggcc atctaaaaag atacaatgct cattaaagta
    17161 agcatagggc gaatactgga aaccccattc ctgaccaacc atttcaaaac ggataatccg
    17221 gtggttgctg cgagctgggt ggttgacccg accatggtaa ccctcattct ctaaacaaag
    17281 ttgacactga ggataattac tagcttgcac caacttggct accgcaatct ctttcggatc
    17341 cttttcaggc ttagagagat tgatggtaat ttcaagttct ccataatcag atggaacacg
    17401 ataagcgata tttttagcaa tggccttgag tttgatgtag tcatttttct gactgagttg
    17461 ataaaaatcc tctatcgctt gctcaggaga gtaggcatag gcttcccaga agtcacgatt
    17521 gacctgactc ggacaaggag tcaccaagtc catcaattca gtaccaagga tttcacgcgc
    17581 agtctgacta tcctcaatcg tctctaatcg aacggtttcc tcaactagct ggtccttgag
    17641 gtcaatcaat ttatccagat tggtctcaac ttccaaaaca ccttctccca ctcgtgacaa
    17701 aacacggttg gtcaggtaga ttcgatccat ttcctcaaat gaactttcag aaatgacatg
    17761 tgttacaaat ttatctacta aggtcactat agagcctcct tttgactagt caaggacgcg
    17821 agtgccacct gcaacttcag cgatatagaa gcttggagcg tatccaacta cttcctcgta
    17881 gtgtttgcct acagcttcct taaaggcctc aacagtatct ttttgaacca aggcaatggc
    17941 acagccacca aaaccagccc ctgtcatacg agcaccgaga actccttctt gtgcccaagc
    18001 tgtgtgaaca agagtatcca attccaaacc agttacttca taatcacgct ccagagaaac
    18061 gtgtgacgca ttcatcaaac gaccaaatgt ttccaaatca cctgcttgaa gggctgcttg
    18121 agctttaagg gtacgttggt tttcaagcac agcatggcga gcacgtttca aacgattttc
    18181 atctttaatc agatagctat attggtcaac ggcccactcg ttcaattcac ccagggtctg
    18241 aatatccaag gcaacttgca attcttccac tgctttttca cactcagcac gacgttcatt
    18301 gtatttagag tccgccaatt cacggcgttt gttggtgttc atgataacaa cgacattgtc
    18361 cttcaaatca agtggcacca agtcgtattc taaagtattg gtatctaagt aaatagcacg
    18421 ttggtcagcc cccataccaa tagcaaattg gtccataatg ccagaattta ctccgataaa
    18481 gttattttct gtttgttttc cgattttaac caaatcgaga cgctctagtt ttaaatcaaa
    18541 gagatgctct gccacgactc ctgtcaagag ctccaaggat gctgaagaag acaaaccagc
    18601 accatttggg atattcccat aaacataaaa atcaaaacct ttgtcaatca cgtgcccagc
    18661 ttcttgcaag aaatgaagga caccttttgg ataattggtc cagttgtgct ctttttcaaa
    18721 cttgaggtca gcgagaggca cttcgataat gcccttgtcc tcaaagttag ctgagtagaa
    18781 acgcaagact tggtcgtcac gcttacgagc tgcaccgtaa gttcccaagg aaatagcagc
    18841 aggaaaaacg tgcccaccgt tgtagtctgt gtgttcacca atcaaattaa tgcggcctgg
    18901 tgaaaagaag gtttggtctg cttcttgacc aaaaacagca agaaagtctt tgcgaagggc
    18961 ttcagtagta agatgttgtg ccatatgaat tctcctttga ctgtccgtta agccatctta
    19021 acgtgtaatc gttttctttc tattatatcc aaggattttt ccaaggtcaa tcctttttac
    19081 taaaatttta gtaaaatatc agtaaaaaga agaaaaacat gatatactaa cctaatcaag
    19141 gaggatttat ggctacctta aaagacattg cacagctagc ctctgtctct atcgcgaccg
    19201 tatcccgcgt cctcaaccgc gaccagagcc tatctgttac agaagaaacc agacaccgta
    19261 ttttaaccgt tgctgaagag ctgggctaca ccaagcacct caagacaggc gagtcccaca
    19321 aacccaagca aaagattgcc attatccaat gggtcagcga acaaggggag ctggacgacc
    19381 tctactacta ccagattcgc ctaggaatag aaaaaagagc ccaagagttg gactatgata
    19441 tcttgcgcta ttttaatgac catcctttta ccttaagcga ggaagtgatt gggattctct
    19501 gcatcggaaa atttagccga gctcagattt ctgcctttga agaataccaa aagcctcttg
    19561 tatttctaga cagcgataca ctttccctgg gacatacctg tattatcacg gatttttaca
    19621 ctgctatgaa acaggttgtc gattatttcc tcagtcaagg gatggaccgc atcgggattc
    19681 taacagggct tgaggaaaca acagaccaag aagaaatcat tcaggacaag cgtctagaaa
    19741 acttcaaaaa ctacagtcaa gcgaggggaa tctatcatga tgaactggtc tttcaaggaa
    19801 gatttactgc ccagtctggc tatgacttaa tgaaggaggc cattcagagc ttgggagacc
    19861 aacttccgcc agcatttttc gcagccagcg atagtttagc tatcggtgcc ctccgtgccc
    19921 tccaagaagc tggaatcagc ctgccagatc gcgtcagcct catttcattc aacgacacca
    19981 gtctgaccaa acaggtctat cctcccctct ctagtattac agtttatact gaagaaatgg
    20041 ggcgagcagg tatggatatt cttaacaagg aagtcctcca cggtcggaaa atccctagcc
    20101 tgaccatgct gggaaccaga ctgacattaa gagaaagtac cctaaatcaa gaataggata
    20161 acataaaaaa cgaatagagt tctaaaactc ctattcgttt tttattcgat tacaatcata
    20221 gacttaattg tcttacgttc atccatatct ttgtaggctt ggtcgatatc ttccagttta
    20281 taacttgaag taaagacgcg acctggattg atatcaccat caaggacgac ttttagtaaa
    20341 aattgcttat cgtatgttgt agcagaagct gccccacctg ctacagagat attttgcata
    20401 aatgtcgaac caagagcacg attattatag tgtgggactc ctacaaagcc catacgccct
    20461 ccattatgaa gaacacctag cgcctgttct atagcagcct ccgtaccaac acattcaagt
    20521 gctgcgtctg ctcctccacc gaggatttca cgcaccttgg taattccttc ttgaccacgt
    20581 tctgcaacaa cagctgtcgc acctgactcc atagccatct tttgacggtc ttcatgacgg
    20641 ctcataagga taatttgtga tgctccacgc atcttagccg cgatgacagc acattgacca
    20701 acagccccat cacctataac aacaaccttg tccccttttt gaacatttgc aacacgcgct
    20761 gcatgatagc ctgtcggcat gacatctgca agagtcaaaa gggacttgag catcccttct
    20821 gtataatcag aaggttgacc agggatttta accagcgccc agtttgcata gtggaagcga
    20881 atatattctg cctgaaaatc accccccaaa ttattgccaa tatgattgtc gcaagaaccg
    20941 tcaaatccag caagacaggc atcacactca ccacatccat gtgtaaaagg gacaatcaca
    21001 aaatcacctg gtttcaccgt cgtaatggct tccccagctt cttcaacaat cccaatcgct
    21061 tcgtgtccac tatttttatg tccagctttc gtttctggat tacggtacct ccataaatct
    21121 gaaccacaaa cgcacgcacg aaccacacga ataatcacat catccgcttc tattatttgc
    21181 ggacgttcaa tgctagcaag tccaacctga cctgcctttg tatatactgc tgatttcatt
    21241 taaaattttc cttccttata aagtttaatt ttgagattta aacgatttaa agctgtctgt
    21301 agctgagaca agcgctcctc taatttttgc ttttcctctt ctaaaatacc aagcctctcc
    21361 tctctcgttt catctccctt ttggtagagc gacatatagt caactaaact atctacagag
    21421 acacccgccg aacgaaaaca cttaataaat tccagcgctt cgatatcctg atcttgaaaa
    21481 tcacgaatcc cagtagcagt acgagtaatc ggtggcacaa gaccaacccg ttcataatac
    21541 cgaatcgtat ccgctgaaat tcccaacaaa tcactggcag atttaatatt cacacgctaa
    21601 cctcctctca tttcattcac tgaattcacg ctattctaac tcacttatct tattatataa
    21661 ctttgagttg actccaagtc aagcattttg tatctaatcg aaaaattttt atcattaaca
    21721 atcatatatc tggagtttat acaatgctct tctcttacca atttttgaaa tatttaaata
    21781 ataaagaaat tactctattc caaataagat agtacccaag tatttttcac ttttttctaa
    21841 tgttgatgct cataactccg ttccaagtca cacacctttc gcttatgggt ttggtgagtt
    21901 tctaggtcag catcaatttc aatggtaata ttttgaaaac cacaatcttt taggaaaatt
    21961 cgaatagact ctttacaagt ttccatatgt tccatttctt ttagacaaac atgtacaatg
    22021 gcattttttt ccaaagcatc catagtccag agattaagct gattaaggct ggccacattg
    22081 tccaatcgct ccaggccact ctttacttgc ttgatatcaa gaccttctgg cacagcatcc
    22141 aagaaaatct tgagtgtaga ccaaaaacgt ggaagggctt ttgaaagaat aaagaaagaa
    22201 atgacaaggg acaaaagagg atctaggata taccagtccg taaatcgaag aacaatcgcc
    22261 atcaggataa cagctaccca ccctagcgta tcttccagaa aatgcaaact cagaatagac
    22321 tcattctttg tctttccctt accaaccacc agactcgcta acagattgat agtaatcgca
    22381 ataattccta accagagaat cccctcatca ttgactggtt gcggatgcaa aatcttcgtg
    22441 acattttcca aaatgactag aacagagccc gttacgagaa tcacagctgt taccaaggct
    22501 cctagcaggc taaaccgctt atagcccaag gtgtactgat tgtcttcttc acgattggag
    22561 attgtttcta gaaaagctga tattccaatt gcaatcgcat ctcccaagtc atgcacagag
    22621 tcagcaagaa cagcgctaga accaaatatt ccacctgcaa taaactcaac aatggcataa
    22681 gtcaaattta agaaaaaagc cacccaaaca gcatattttg ccttcatatt tctcattcct
    22741 ttgttataat agatttatga acaccttgtt cattatcatt atccactaaa actcaaagaa
    22801 aggatagaag caaaacgtca gctttattca gttctgaaca atttgcctta agtgtccata
    22861 tgactaacat tgaccgccgt atcagcaaaa ccaaaaaagc catctatcaa gcttttatac
    22921 aacttttgaa tgctaagggc tacgaggcca ctactgttca ggatatcatt gatctcgcag
    22981 atgtgggacg atccaccttt tactgtcact atgagagtaa ggagcttctt ctggaccagc
    23041 tctgccgcta cctcttccat catctttttg aaagagagca agccatttca accgaggact
    23101 acctcgccca cctctttctg cattttcata aaaaccaaga ccatatcacc agtctgctat
    23161 tttccaaaaa tgactacttc ctccgtcaac tccagagaga gcttgagcac cacgtctatt
    23221 ccgtgctagc tgataattta aaagaagccc accctaatct gcctacttct tacctccaac
    23281 acttggtcat gtccaacttt atcgagacat tgacctggtg gctcaaaaaa ggtcaagatt
    23341 tcacagacca ggaagttgtc caattttatc tagaccttct cattcctaaa aattgaatat
    23401 agagtaaagc ttcagttgtc ttatttctag gttactgagt tttttatctt ttcaacaaca
    23461 aaagaggacc cgccgatcct ctttttcata ctataaatcc ttgattatca actatatctg
    23521 ttttaatcga aatctcaaaa cagcactttc aaacatcttt tcctagttaa gtaaatcagt
    23581 attctgctta gctgccttgc tccattgata ccaaccaact agactgttaa taagataaat
    23641 tagatatttc ccttgaattt gcaggctttc tccccaccag agatagattg aaaaaacatt
    23701 ggtagccgcc cagaatatcc actgttcacg gtaaacagct gtcatgagga tttgccctac
    23761 cccattggtt gcatctgtga ttgaatcacg atagggacga ttggcaccaa tagactgata
    23821 aatgaagcca aaggccaacc accaaagcac actaatggaa agatactttg tccagccctt
    23881 gccgtccagt ttacgcgcga caaactcctg cttttccttc ttaaactgtg cctgataaat
    23941 ccaaactaga agtccaattg gctgcatgac tgtgaagtaa agtgtcgtca gcacctcacc
    24001 ataaaagcct ttctgtaggg ccaaaataag gtaaataaca gagttaatca agccaaaaag
    24061 ataattactt gctcgacctt ccgatacaaa gattacacag ataatccctg tcaagctaca
    24121 aatcatccca atccagtcaa caatacgatg ttcgtaaacc aactccagcc agagaggaaa
    24181 acttcctaaa accagcaaat aaatccactg ggcaaaacta cgatgggcaa agaggtcatc
    24241 ccagatagcc ttcatagttt ctgaaaatcc taaatcagcc atagccgcaa ccatacgacg
    24301 gtaaccacct gacatttcac ctagggttgt tttgatattt tcaattttct tttgcaaata
    24361 agtatgcatc atttctcctt ttgtttttaa agagccgtgt ctggatagac tttcggacgc
    24421 aacgctctat tagataatga actgcctata cacaagattt ctaaccttag tcgacatgag
    24481 ctgaaacctc ttatttgtta agtagttcac aaaatattat acacctattt tatgaatagt
    24541 caactgtatt tacagtaaaa ttttagaaaa tcatgaaaat tttctctttc tttccatttt
    24601 aagtgacatt cagtcattct cacatcaaaa aagcccagac gaaattgtct gagcattctt
    24661 ttatctagtc gtttaaggaa gttgagttca gtatgtttaa agtctctgtc ccatcatttc
    24721 ttcaacaaac cttgttcttg gagaaactcc ttggctactt gctttgctga cttgccttca
    24781 acaccgactt ggtagttgag ctggctcatc tggctttctg taatcttacc agccaatgta
    24841 ttaagaactc tttccaactc tgggtgtttc ttgagaagag cttctttcat gagtggagcc
    24901 ccttgataag gtgggaagag ttgcttgtca tcttccaaga cctgtaaatc ataacgctcc
    24961 aattccgcat cagtcgaata ggcatctgta atttgaattt cacctgactg aatcgcttga
    25021 tagcgaagag caggttccaa ggttgaaaca ttgagattga gaccatacat tgattgcaag
    25081 cccttatttc catcttcacg gtcgttaaac tcgagtgtaa agcctgcctt caactgacct
    25141 tccacttttt tcaaatccga aatggtcttc aagccatatt cttgcgcaat ctttttcgga
    25201 acagctacag cataggtatt ttgataagac ataggtttga gataggctag atgatcctgt
    25261 ttggcaatgc catcacgcgc cacctgataa acctgctctg gctcatgact cactttaggt
    25321 gatggttgaa gcaaactttc agtcaccgta ccagtaaatt caggatagat atcaatgtct
    25381 ccgcttttca acgcttcata aaggaaagtt gttttcccaa agttaggctt aacggttgct
    25441 gttagacttg tattttcttc tattaaaagt ttatacatat tagccaaaat ttctggttct
    25501 ggaccaattt tccctgcaat aatcacgttt tctttctctt tttgaaccaa gagggctgga
    25561 ctataagata gacccagcaa taccgtcacc aaggcaaaac ctgagaaaat cgtccgtaat
    25621 tttgcttttt ccattacttt tagtaggaag ttaaaggcaa tagcaagcac tgcagaagaa
    25681 agtgccccaa tcaaaatcaa actggcatta ttacggtcaa ttcccaacag gataaaggaa
    25741 cccagtcccc ctgctccaat caaggccgcc aaggttgccg taccgataat caaaacagct
    25801 gccgtccgaa tcccagacat gataacaggc atggcgagtg gaatttcaaa tttcttgaga
    25861 cgttcccatc tggtcatccc aaaggcaatc ccagcctctt gcaggttcgg atcaattccc
    25921 ttcagcccag tgatagtatt ttgcaaaata gggaaaatcg cataaatcac tagagctgtc
    25981 aaagccggca aggtcccaat tcccatcaaa gggataaaga gccccaacaa ggccagagac
    26041 gggatggtct ggaaaatacc tgcaatctgc aagacccagt cggccagctt ctcatgatag
    26101 cgaagaaaaa cagccaaggg aatcgcaagc aaaatagcta gtaacaaggt caaaagtgac
    26161 aactgcaaat gttgagatag agctgtcaac caatcactaa aacgatcctg aaaagttgca
    26221 attaaattag tcatgaacac tacctccaaa caggtctgct acaaagtctg ttgcaggcgc
    26281 ttttaaaatt gtctcgggat tcgctacctg gcgaatttct ccatcctgca agacagcaat
    26341 acggtccgcc aacttcaagg cttcatccgt atcatgggtt acaaaaatcg ttgtcatccc
    26401 aaactcttta tgcaattctt ttgtcagaac ctgcaactgt tttctcgaaa tagcatccaa
    26461 ggccgaaaag ggttcatcca tgaggaaaat cttgggctga ccaatcatag ctcggacaat
    26521 accgacccgt tgctgttctc caccagataa ttcactaggt aagcgatgcc catactcggc
    26581 tactggtaaa ccaaccttag ccaaaagctc ttctgttttc ttcgtaattt cttccttgct
    26641 ccaccccttc atttcaggaa tgagagcaat attttccgca actgttagat ttggaaaaag
    26701 agcaatagcc tgtaaaacat aaccagtaga aagacgaagt tcacgctcat catagtcttt
    26761 gatgcgcttc ccatccatat aaatatttcc atcagttggt tccaaaagac ggttaatcat
    26821 cttgagcatg gtcgtcttac ctgacccaga aggccctact aaaaccataa attccccatc
    26881 ctcaatctgt aagttgacat ctctcaagac atccttttct gtgtagcgca gtgctacatt
    26941 tttgtattca atcattcttt gtcctcaatt taaaacttcc ctcgattggt caagtcttct
    27001 accttaggca tgacttcctt attatcccaa tgctccacaa ttttcccgtt ctctaaacgg
    27061 aagatatcgt actgggcata agcaacgcca tcaatctgag tctgaccata gctaaccaca
    27121 tagtttcctt gtcctaagag ttggaaaaca aagtcaaaag tgacactata ttcagccaca
    27181 tagtttttat aagcagcact tccttgtcca atatcatgat tatgctgaat caaatcgtct
    27241 gccacataat cactccactg ctctagctcc ccattttgga aaatttctgt caagaaacgg
    27301 cgaaccagct ttttattttc tgctttcttg tccaaatcct tgatttcaaa atctccaaaa
    27361 atttgatcta gttggtcatt ttcaggtgtt cgatagtagt caatgacatc ccaatgctca
    27421 acaatacgac cattctcatc cgcacggaaa gtatccgtcg tcacccattg agcttctcca
    27481 ccattcagat attgatgaac atgaacaaag accagattgc catcctcaat ggtgcggaca
    27541 atcttaatct gacgctctgg atgacgctca aagaaatctg caaagaaggc tgcaaatcct
    27601 tctttcccgt caggaacacc tgtcgaatgt tggatatagg tatcccctac agactgggct
    27661 tgagcctcag caactcgtcc gtcttgaatg gcatggatgt ataggttgtg agcatttttc
    27721 acttgttgtg acatattcta aacctcattt cccttctctt tcagattcgc caaaattctt
    27781 tcttgaaaac cttcaaattg gtgaatttct tcctctgaaa atcctttgta aaagatagta
    27841 tccaatttct gactgacacg atgccccact tctttctggg acttgcctaa ctccgttaaa
    27901 actaaatact tcttacgctt gtcttttcca cacggactaa caattacaag cttttgttcc
    27961 tctagctttt ttatcatagt cgtcagcgta ttattcgcaa gtccagtcgc aagcgcgata
    28021 tctgtcgcag ttgcgcagcc agtttcacta ttccataaaa ccgctaaaat cttgccctgt
    28081 tcacccctat aaagagcctc aggatcttga ctcagtaact tttgaaaaat ccgcccattc
    28141 aacaaacgaa tatgatgggc tagcaaatga ccatctttca taacacctcc aatttatttc
    28201 gatatcgaaa tgaataaaac aattgtaaca ctcatcgttc taactgtcaa ctatttcgat
    28261 ttagaaataa tttttgataa ttatccacac caccatactc cggctcaact aacttttaac
    28321 gagagtttct aaactccttc gtcctccagt ctacaaaagc cttccattcg tactatccta
    28381 tattttatga ggggacacat ttttcctatc agaccattta ttttaaagat agaagtaaat
    28441 cataattgct tccatctgtt cttttatagt atattgaagt tagactagag cactgtatct
    28501 tctaaaacat tgatagaaag cgatttgaat ttcccaatca atttgttcgt atttatagca
    28561 tttcgaaact ggaataggac accatgactg ctaaaagatt tctataaatt catttaattt
    28621 cctcaatcaa tttgttcata tcttatttca ttccgctata atttcacctt accctatctt
    28681 tttcgtagca cccttcaaac agcctatccc ctaccgtttg acgattcctc acttcgctcc
    28741 acttccatta cagaagtttc ttcactacta tgggctcggc tgacttctca tgattccttg
    28801 ttactactat ttgaacgctc acgagataga tcttacaaaa aatgctttga tccacaatgg
    28861 aatcaaagca ttttaaagag ttcctcatac ataagcgcag aagtcgcagt tcctctgtac
    28921 ttggcttctt ctcttttgat aaagcgagcc aagttgagca actcaggtgc tggatgtttg
    28981 ggatttagga gcaattcacg attgaccagg cctgagagac gaactgcctg caattgctca
    29041 tttgtagtag gcagtttttt agcagtctct aggagagcag caactaaatc ttcactcaaa
    29101 tcatgtcgag catgattgta aagatctttt ataaggcttt ctaggtttgg ttctgccatc
    29161 cctaccacct cccttatggt ttaataatgt ttaatcaaat caaccgttga acgatccaat
    29221 ttcttcacca aggcttgtaa gaaagcttgc gcttctagga agtcatccat tgcatagagg
    29281 gtttggtgag aatggatata acgagcgcag acaccgatag ttgttgatgg gacaccacca
    29341 tttttcagat gagctgcacc tgcatctgtt ccgcctttac cacagtagta ttggtacttg
    29401 ataccagctt cttcagccgt tgtcaaaaga aaatccttca tccctgggag aagcaagtga
    29461 cctggatcat agaaacgaat caaggttcca tctccaatct tgccttgacc accgtagaca
    29521 tcacctgctg gtgagcaatc aactgcgagg aagacttctg ggtcaaactt ggttgtagag
    29581 gtatgagcgc cacgcagacc aacttcttct tggacgttag aacccagata gagttcattg
    29641 ccgagttttt gacctgataa agcttcagct agctcgctta ccatgaggac accgtagcgg
    29701 ttatcccaag cttttgagat gatatttttt tcattggctg tcaaaattgc agaactatct
    29761 ggtacaatgg tatcaccagg acggatgcca aaactttctg cctcagcctt gtccgcaaaa
    29821 ccaccatcaa aaacgatatc ggcaatggct ggcatggttg gtcccccctt tccacgagtc
    29881 aaatgcggag gaacagaacc tgaaatcaca ggaatttcat gaccatcacg agtcaagagt
    29941 ttgaaacgtt ggctgctaac caccatgggg ttccagccac cgatttctac gacacggaag
    30001 gtaccatctg gcttgatttc gctgaccata aaaccaactt cgtccatatg agaagcgacc
    30061 aagacgcgcg gtgcatccac agcttctgaa tgtttgatac caaaaatacc acccaagcca
    30121 tctgtcacca cttcatccac atgcggtgtc aacttttcac gaagataagc acggacaggc
    30181 gcttcatgac ctgagactgc agcaagttct gttacttctt taatttttga aaataatgtt
    30241 gtcatttcag ttccttcttt ctttcatcca ttttaccact ttttatagga gaaggatagt
    30301 gggaaggtgg atttctaagt tagtatctta gtcctgctct atcttagaaa aggatagtat
    30361 tctcttgcat gtagtgcaaa atctagtaaa cattccaaaa ttaactcgaa tatttatttc
    30421 caaacaaaaa aacaatacac catcaaagtt gtttggattt ttcatgaaat ttacagaaaa
    30481 tagttgactt ccctttcttc tttctttaaa tatatagttg gttgagtttg gaatagtacg
    30541 ctgtagctgc taaaacattt ctagaaatta atttgacttt cctaatagag ttgttcatat
    30601 cttatttcaa tttactatag tacaaaacta gaaaaggaaa aaatcatgac caaaacaatt
    30661 cttgttacag gtgggactag ctacattggc tcccataccg ttaaagctct tttaaatgct
    30721 ggctatcagg tgcatgtcct cgataatctc tccacaggaa atcgagcggc tgtggatagt
    30781 cgtgctagct ttaaagaact ggatgtttat gatgctagcg ccttaaaggc ttacttagaa
    30841 gaaaatcaga ttgatgctgt cctccattgt gcaggtgaaa ttgttgtgag cgaaagtatt
    30901 gaaaatccaa gtaaatactt cactgccaac gttgctggta tgaaccaagt tctcaaagtc
    30961 ttatctgaag ttggcattca aaaaatcatg ttctcttcga ctgcttctct ctatggaaat
    31021 aactgtattg acaagccggt gactgaagat accctgctcg accctgtcaa cccttatgca
    31081 gagacaaaac tgatgggcga acgaatgatt tactggatgg ccaatcgcta cgactggaaa
    31141 tatgttattt tccgttactt taatgttgct ggggctgaaa tggatgcttc aaacggtctg
    31201 cgtgtgaaaa atccaactca catcattcca aatatcaaca agaccgcatt gggacaaaat
    31261 gatagcttaa aaatatttgg agatgactac gatacacgtg acggttcatg tattcgagat
    31321 tacatttatg tcttggacct tgcataggct catgttaaag gaatgaacta cctatttcaa
    31381 gaagacagtt cttctcaaat ctttaactta ggaactaaaa aaggctatac tatcaaagaa
    31441 atctttaaaa ctgctgaaga attactaaat taaaaaatcc cacacgagat tgttgctcga
    31501 cgtgctagtg acccagccag tgtcctagca gatgcttcaa aagctaaaca atatcttgat
    31561 tggacggcta gctactccct cgaagatatt attttatcag attaaggtaa aaacatttta
    31621 gaataggata acaaaggaga aagtcttgtt gctctctcct tgttgtattt attaaattgt
    31681 cagaaatttt attgacagat tagaaaaata atgttacatt tatatccgca ggtatctttc
    31741 gataccaaat ctacatgaaa ggacggggta tgaaactttc tcattattta attggcttac
    31801 ttctactcct agtctttctc tctattagca ttgggaccag tgatttttca tggggaaagc
    31861 tatttgattt cgaccagcag acctggctcc tctttcaaga gtcccgtctc ccaagaacta
    31921 tcagtattct cctgactgcc tctagtatga gtatggcagg ccttctcatg cagactatta
    31981 cccaaaatca gtttgctgca ccgagtacag ttggaacgac tgaagccgcc aaactgggaa
    32041 tggtgctgag cctttttgtc tttccatcgg ctagtctgac ccaaaagatg ctcttcgctt
    32101 ttatttcatc catcgtattc accctcttct tcctagcctt tatgaccatt tttactgtaa
    32161 aggaaaggtg gatgttacct ctgattggga tcatctatag cgggattatc ggctcagtca
    32221 cagaagttat cgcctatcgt ttcaatctgg ttcagagtat gactgcctgg acccagggct
    32281 ccttctccat gattcagacc catcagtatg agtggctctt cttaggcctc atcatcctga
    32341 taaccgtttg gaaattatcc caaaccttca ccatcatgaa tctagggaaa gaaaccagcg
    32401 agagtttggg gatttcctac tccctacttg aaaaactggc cctctttctg gtggcgctaa
    32461 cgacaagcgt caccatgatt accgtgggtg gcctaccatt tctcggagtt atcgttccca
    32521 atcttgttcg caagcgctat ggagataatc taagtcaaac caaactcatg gtcgcactgg
    32581 ttggtgccaa tctagttctg gcttgcgata tcctatcccg agttctgatt aggccctatg
    32641 agttgtctgt cagtctcttg ctaggaatca tcggtagtct cgtctttatc ctacttctct
    32701 ggagaggggg acgaaaagat gcagactaaa agcaaacata ccaagctctt ctggattctc
    32761 attattcttg ccatcggagc ttgtcttctc tacttttggc ccatcactca cttgtcagcc
    32821 tttgcttgga agttgcgttc ccaaaagatc atcgtttatc tcttggtagc catcgcgact
    32881 gggatttcga ccattagttt tcaaaccctg acggaaaatc gcttcctgac gcctagtatt
    32941 ttgggaattg aatccttcta cgtcctacta caaaccctac tactggtttt tgaaagcaag
    33001 tttcttcaac ttggcaaatc ccctatctta gaattcctag tcttacttct tgtccagtcc
    33061 ctcttctttc tcgccttaca aggttacttg aagacactga tgaagcaaga cctggtcttc
    33121 atcctgctga tctgtctagc gctcagaagt ctctttcgaa atatcagcac cttccttcaa
    33181 gtcctaatgg atccaaacga atacgataaa ctgcaaaata gtctttttgc ctcctttcaa
    33241 catcttaaca cttccatcct agccatcggt tctctgatca tcctcgcttt gacaatcttt
    33301 ttctttcgaa aagcagtcgt tctagatgtc ttgcacctgc aaagagaaac ggctcagata
    33361 ttgggactcg atgttgaaaa agaacagaaa gagctcctct ggggaatcgt gcttttgacc
    33421 tcaacggcca ctgccttggt aggacctatg gccttcttcg gctttatgct ggccaacctc
    33481 acctacctga ttgtcaaaga ctatcagcac aagttactct ttatagtggc cattctggtt
    33541 ggatttatta gcttaacctt ggggcaagcc ttgattgaac gagtctttgc actggaaatt
    33601 cgtatcagta tgatcattga gagtgtgggt ggcttcttat tctttatctt actatatagg
    33661 agggctcgtc agtgaaactg gaaaacattg acaaatccat tcaaaaacag gatattttgc
    33721 aaggcatttc gcttgaagtc agtcctcaaa aactgacagc ctttattggt ccaaatggtg
    33781 ctggaaaatc gactctcctc tccatcatga gcagactaac caagaaagat cagggagttc
    33841 tcagtatcaa aggacgtgaa atcgagagct ggaattcgca agaactggcc caagaactaa
    33901 ccatcctaaa acagaaaatc aattaccaag ccaaattgac tgttgaagaa ctggtcagtt
    33961 ttggacgttt tccctacagc cgaggtcgac ttagatcaga agactgggaa aaaatccgag
    34021 aaactctgaa ctatttggaa ctgaccaact taaaagaccg ctacatcaat agcctgtcag
    34081 gggggcaact ccagcgcgtc tttatcgcta tggtactggc ccaggatacg gactttatct
    34141 tgctggacga accactcaac aatctcgata tcaagcaaag cgtcagcatg atgcagattc
    34201 ttcgacgact ggtggaggaa ctcggcaaga ccattatcat cgtcctccac gatatcaaca
    34261 tggccagtca gtatgcagat gaaattgtcg ccttcaagga cggccaggtc tttagcaagg
    34321 gaagaaccga tcaaatcatg caggctgacc tgctcagtca actttatgag attcccatca
    34381 cgctagctga tatcaatgac aaaaagatct gtatctatag ctagtaacat aaaagctcaa
    34441 gttagagaac cttcagtctc ttagtcaata agattaagag actccctaaa tcgttatcac
    34501 attttaaaaa ggagaaatta tgaaaacatc ccttaaactt tatttcactg ccctagtggc
    34561 cagcttcttg ctcctacttg gtgcatgtag tacaaactca agcactagtc agacagagac
    34621 cagtagctct gctccaacag agataaccat taaaagttca ctggacgagg tcaaactttc
    34681 caaagttcct gaaaagattg tgacctttga cctcggcgct gcggatacta ttcgcgcttt
    34741 aggatttgaa aaaaatatcg tcggaatgcc tacaaaaact gttccgactt atctaaaaga
    34801 cctagtggga actgtcaaaa atgttggttc tatgaaagaa cctgatttag aagctatcgc
    34861 cgcccttgag cctgatttga ttatcgcttc accacgtaca caaaaattcg tagacaaatt
    34921 caaagaaatc gccccaaccg ttctcttcca agcaagcaag gatgactact ggacttctac
    34981 caaggctaat atcgaatcct tagcaagtgc cttcggcgaa actagtacac aaaaagccaa
    35041 ggaagaattg gccaagctag acaagagcat ccaagaagtc gctactaaaa atgaaagctc
    35101 tgacaaaaaa gcccttgcga tcctccttaa tgaaggaaaa atggcagcct ttggtgccaa
    35161 atctcgtttc tctttcttgt accaaacctt gaaattcaaa ccaactgata caaaatttga
    35221 agactcacgc cacggacaag aagtcagctt tgaaagtgtc aaagaaatca accctgacat
    35281 cctctttgtc atcaaccgta cccttgccat cggtggggac aactctagca acgacggtgt
    35341 cctagaaaat gcccttatcg ctgaaacacc tgctgctaaa aatggtaaga ttatccaact
    35401 aacaccagac ctctggtatc taagtggagg cggacttgaa tcaacaaaac tcatgattga
    35461 agacacacaa aaagctttga aataagccac ttcaaactca atttaatact caatgaaaat
    35521 caaagagcaa actaggaaac tagccgcagg ttgctcaaaa cactgttttg aggttgcaga
    35581 tgaaagctga cgcggtttga agagattttc gaagagtata aaattttgac attctaaaac
    35641 gcatcctatc aagttcactc aaacctgata ggatgcgttt ttatcatttt gaaatctatt
    35701 taccccacct cattcccctt cttgatttcg tttaagggaa aagtggtctg gaacggggtc
    35761 cttacctgtt ttcgaccagg gatgacaacg taaaatccga gccaagccca tcaatacccc
    35821 cttaaaacca tgtttttcaa tagcctgaat catgtagttg gaacaagtca gctcaaagcg
    35881 acaagagggt ggaaagactg gtgagataaa acgttggtaa aagcgcacag gcgctattaa
    35941 aattcgtttc attatttctt agttacagcc atggtgtgta gttggctgat ttctttttta
    36001 ttaagacgac gggattctcc tggacggagt cctgtcaagt ctaggtgtcc gaaacgagtc
    36061 cgagacaact tatctacttg gagaccaaca gcttcaaaca tctttttaac ttgatggtta
    36121 cgcccttcat ggatggtcaa ctgcaccaca gagcgatttt tgactgggtc cactttgaga
    36181 atttcataaa cagctggctt ggttttctta ccatcaatct caagaccacg ggtcaagggg
    36241 cgaagattgt ccttattggt cacaccttta acacgcgcta cataaacctt gtcaatctca
    36301 ttacgagggt gaatcatctc gtctgtaaag tccccatcat tggtcaaaat caagactcct
    36361 gatgtatccc agtccaaacg acccacaggg taaatgcgct ctttgacatt gggcaagagg
    36421 tcgacaaccg tcttgcgacc cttgtcatct gttacactgg aaatgacacc gcgtggtttg
    36481 ttaagcagat aatagacctt ttcttcgttg tagataggtt gaccttcaac ttcaaccttg
    36541 tcgcctgact tgatagtggt tgctagttca cgcaccactt ggccgttaac cgtcaccaaa
    36601 ccttgcttga tcagctcttc tgcttttctc ctactggcca cacctgcgtg ggcaatatac
    36661 ttattgattc tcatcttctt ctatcctttc accaaataat tggctttctt gggcttgaat
    36721 ctcaagctca tcaatcactg gtaattcttc taaatggttt atccccatgt aatctaggaa
    36781 ataatccgta gtcacataga ggttggggcg ccccaatact tcctttttcc cgtcttcctt
    36841 tatcaggtca aaagcttgca actttgccaa ggctccactc gagttaaccc cacggatggc
    36901 atcaatttct atccgcgtaa tcggctgttt gtaggcaata atggacaagg tctcaagggc
    36961 agcccgagac aagctctggt tgataggcgc cttagagtat tccttcaaaa tctctgcaaa
    37021 ttgaggcttg gtcaccaatc tataagcacc acttgtctca atcaaagcca aactggaatc
    37081 tgggtccttt tcatacttct gggctaattt tcctaaactc tgctggatgc ctgtcggtgg
    37141 cagagagagg agttcagcta actggcggac ccgaatccca tcttcacccg ctacaaacaa
    37201 gagcgcttct atttttgcta aagtactcat ctttcctctc tatcaagtct agctttgagg
    37261 cacttgactt tcttccttct tttccatgag atagatatct ccgaaactct cctcttgcac
    37321 gaggatcagc tcctgggttt tgattaactc tagggttgcc aaaaagaggg tgatgacctc
    37381 ttggacattc tgggcttcct tgaacaaatc ctgcaagcgc aattgatctc gtccaatcaa
    37441 ggattctttc acaataatca tcatgtcctc aatcttatac tcatcccgca agatagtcgt
    37501 gtgattttgt gcaaactcct cttttttctt ggctaggata tttgaaaaag ccaaaaagag
    37561 gtcaatggtc gtcttgtcat gcacaagctc cgcatcttcg taaatcaact ctgtcggcgc
    37621 tttggaataa tactgggccc gttcttggtg cttggcttcc aagtgctcac ccaagagctt
    37681 gaacttgcga tattcttcga tttgagagag gaggtcctgc tccaggtcat cccccaagtc
    37741 tgtcacttct gctaccttcg gaaggagttt acgactctta atcagcatga gctgactagc
    37801 catgaccatg tactcacccg tcacttccag acgcatggcc tgcagggttg agacataggc
    37861 tagatactgt tcgatgactt ccgtaatggg cacatcgtag atatccatct ggtacttaga
    37921 aaccagatgc aagagcaagt ccaggggtcc ttcaaaatct tttaatttaa tatccattat
    37981 ctatattttt ctaaggtcag gactgttttt aatcctaatt tttttgcaat ttcgtacaaa
    38041 tcgaccttgt tttctatttg tcttagaata aactgttcac gtaagacttg agctgataag
    38101 gatggaaaac ctttctcctt gacaaaagat tctaactgac gaaaggccca ctgacgagaa
    38161 tagggtttct ctcctctttc aaaaagatag gtctgcccca tcaagggttc caattctgaa
    38221 agcaaggccg tgggaatggt gacaatcctc tgttgggaag ccttgctgat tcgcagcacc
    38281 tgaaaatcca gattgatgtc cgcaaccttg atggctaaaa tctcactagg caagagcccc
    38341 atttctagga ttaagagcgc tagcaagcgg ccctctggat ggtcgctttc ctgccaaaaa
    38401 gagtctaggt atagaatctc tggcttttcc gtcttctttt cagcttgttt ggctaattcc
    38461 aagcggtaaa agctgtccac ctctcctttt tgatagagaa agtatagaaa ttggttacag
    38521 gccgaaatct ttcgcttctg ggcgctgatt tttagattgg ctagctgggc ttggtaaatc
    38581 ttgagactgg tctcagaaat ccgctcacct accatgtcta aaaattgctc caaatcatac
    38641 ttataggact gcttggaatt gacagacaag ccctgctttt cctctaaaaa ggctgaaatc
    38701 ctgtctctca ttggcatcga atctcatatt ccttactaaa gtcatgcaag agggcattaa
    38761 cggccttgag gatggacttg cgcgtaataa tcccttggaa aataccctct gcatccacaa
    38821 ccggtaagaa ggactcatct actagcttgt gcaagacctc cgtaatggtg aaatcaggcg
    38881 aaacaaccgc tacgtccgtt tttgtcatat gaacgatatc cgtatccgcc atgatttctt
    38941 ggctcaagtc atgctccatc tgataagcca taatatctct gagtccaatc gtcccaacaa
    39001 actgtttttc atctgtcaca acgggaacac gggtataggt catctgactg agcaagaggg
    39061 tcgcatgatc cgcattgtgg gtatcaatca acacagctag atttttagca ggggtcaaaa
    39121 aagtttcctc ctgccccaac aagaaagtct caaactcctt ggcaatcatc ggctaaactc
    39181 cttggacaaa cctggataca cctcgtgatc tcgtgtcaaa aagtccactt tgaagtaact
    39241 atcatcaatc tccacacgag catagagaca ttctctgatg gtacctcgtg gttgactgat
    39301 agaacctgga tttagaaaga ggatcttgcc ttccaaccaa gcacttggca catgcaagtg
    39361 accatagagg cagatagcgg cctcttcctc ctgagcccag tagtccaact tttgaaagtt
    39421 gaaattgatg tcaaacaagt gaccatgagt ttggataatc ttggtcgaac caagctcagt
    39481 caccagacgt tctgggtagc cggcgtagaa gtccatgttc cctttaacaa cgcggatgcc
    39541 ctcccaaagt ggagaatccg gacgtagttc agaatcgccg ttatgaaaaa cggcatcgac
    39601 tttgcccaca tagcgatcac ggacttcttc cacaatcaag ctatcgccat gggaatcgct
    39661 cattacaatg atggtttgct ttgccatgat ggaaatacct ccaaaagttt cttaacggct
    39721 aaggcacggt gagattgact atttttttct tccagggtta attcagctga tgactcacct
    39781 gtttctccta caaggaagag gggatcatag ccaaagccat tttcaccctt aggttcaaag
    39841 ttaatataac ctgaccagtc tgcttcaaca actaaacttt ccttatttgg gctggctacg
    39901 actagggttg tgtggaactg agccgagcgg tccttgagtt caaagaccat ggccaattcg
    39961 tgcaagagtt tggcattatt ttcacggtca gttgctccca cacctgcgaa acgagctgac
    40021 cagacgcctg gtaagccacc aaggacatcg actttgagac cagaatcatc tgccaaaacc
    40081 atcttgcccg ttaattgaga aatggtttct gccttaaggc gggcattttc ttcaaaggtc
    40141 atacctgttt ctgctacttc aggcaggtca gggtagtcat taagattttc cacatcgtag
    40201 cctaacttat caaagatagc tcgaaattcc ttggttttac cttcgttacg agtcgcaatc
    40261 aacaaggttt ctctgacctt gcttgtctca aagaaatcat gaacattgac cccttcttta
    40321 ggcaattcta catacaagag ttgcccattt tcaaccaaga gcagggcccc atgacgttga
    40381 ataacttcca agtttcgtcc catttcttga ttaagcatgt ctaccacaaa ggagaacaaa
    40441 cggtaggtag aaccatagcg taaaacagta actgaaagcg ggaaaccata ctcttcatct
    40501 ccaaatattt tggagaattc aaacagagga aaatctgtct tatagtcgct caaactgtta
    40561 acgccaccaa aaatactata agacccaaca taccagtcct ggtcatcctt atattcataa
    40621 attttatttg tcataattct acatgctcca catgaatctc tttttccagc cattcttcac
    40681 caatttgtgc aaaactttgg ctactggctg ttgtgtaaaa acggtgatgg agtggtccag
    40741 catcgcgacc acgattgatt tcaaaataat tgagtaagac tgagatatcc cgtacgcact
    40801 ctgccccact atcgatgagc tgaacctttg gccccatcac attttggata atagggcgaa
    40861 ggagtggata atgagtacag cccaaaatca ggctatccac ctttccaacc aagggacgca
    40921 gggtttcata gaccaccttc ttggtaacac tggttgacag ggcacctgac tcaaccaagg
    40981 gagcaaactt gggacaggcc aagctctcca cctgtaagtc gggatccaga tcatggattt
    41041 tcttacggta tatgtctgat tgtaccgtca tgggcgttcc aatcactccg attttcccac
    41101 cttgactgga cttgatggct gccgaagctc ctggcaaaat tacacccaag acaggaatat
    41161 ctagttgagc cttgatttct tcccagacga ccgcagtcgc agtgttacaa gcaatgacaa
    41221 tcattttgac atccttagtc aagagaaagt tgaccagctg ccgagtatat tcacgaattt
    41281 gctcagcagg acgggggcca tagggcgccc gcgccgaatc tccaatatag acgatttctt
    41341 catggggaag ctggcgcatg agctcgcgca caacggtcaa gcccccgaca cccgaatcca
    41401 aaaaaccaat tggtcgatta tccatacagt cttctttcta gtcttttttc tgattgatcg
    41461 ttcattatga ttccttgtac tgaacgaact gaccgacagc ttgatagaat gtcaactacc
    41521 tctctcttaa tcataatcaa atatcaatag aatgcaagga aaaagtctca tccctaaacc
    41581 ataaccaaca tagtgagaag tctggaactt tcatcccaga cttttcctta tttatttttt
    41641 ctttttattg ttagcaaggg ctgccttttg ttggcggatg atttggtggt aaacttgttg
    41701 taccttagct tcgcttggtt tttgaccatt tgcactcaaa agagtacgaa ctgcttcagc
    41761 attcaaacgt gggttgtcag caaattcttt ttcgatttgc ttacgaacca agtacattcc
    41821 tccaagagct cctcctagaa aagctagcac aatcaataca attgctaaaa gtaaatccat
    41881 catttttctc ctgtttcttt ttgagtccct ttcattatac cacaaactag ccaccctgac
    41941 cagtttgttc tacactttca gggatggaat agacagcaaa aagaaccctg cttttctgaa
    42001 aaagaggtct ccttgctaag tttatactca atgaaaatca aagagcaaac taggaagcta
    42061 gccacaggtt gctcaaagca ccgctttgag gttgcagata aaactgacac ggtttgaaga
    42121 gattttcgaa gagtattaat ttacataaat agccagtgtt tgatagggtt tgagtagaat
    42181 tttctcagac acttctgcat cttcatagtt tgatatcaaa atctgtccat tttggtagac
    42241 tgctggcaag tcgatttcca cttctttagc ataaaagtta ttgagcacta gtaacttttg
    42301 atcctcaaac tggcgttcaa aagcgtagac ttgtttgcta tcttcaaagg ctggtttgta
    42361 acttccttct gaaatgattg gcatttcctt acgcagtcga atcaagtctt gatagaaggt
    42421 aaaaatcgga ccctggattt cattttctac attgatgtat ttataggatt taccagcttt
    42481 caaccaagga gtgcctgttg aaaatcctgc attttccgaa gcatcccact gcatgggaat
    42541 gcgtgaatta tcacgcgact tagcttgaat aatctggaag gcttcttgct gactctttcc
    42601 ttcttctaag agcatctgat aggcattaag cgattcgaca tccacataat cagccataga
    42661 atcatagtct gggtcaatca tcccgatttc ctcacccatg tagatataag gtgtcccacg
    42721 tgacaggtga atgctggctg ctagcatggt ggctccttcc ttgcggaagt tttgaatatc
    42781 gacaaaacgg ttcaaggcac gtggttgatc gtgattgttc caaaagaggg cactccaacc
    42841 gtctttatca ctcatttcct taccccaact atggtaaaga ctcttcaact cttcaaaatc
    42901 aaagggagcc aaggtccact tttgtccatc cttatagtcc accttgaggt gatgaaaatt
    42961 aaaggtcatg gataattcct gacgatcagg cgacgaatag aggacacagt tttccatggt
    43021 ggtagaagac atttccccaa ctgtcataaa gctatcgtca gatccaaaag tggcttggtt
    43081 catcatacgc aaatagttat gaacgatggg tttgtctgta taagctggct tcccttcatt
    43141 ttcaggacag tccactgaaa cctcgtcctt accgatcaaa ttgatcacat caaatcggaa
    43201 acctttgaca cccttgtcgc gccagaaatt aacaaccttg aaaagctcct tacggacatt
    43261 ggaattgcgc cagttaaggt cagcctgggt ctcatcaaat aggtgaagat agtatttccc
    43321 agtatccccg aaaggcgccc atgcagaacc accaaactta gactgccaat ctgttggttg
    43381 gtcttggatg aagaaaaagt cttgataata cttatcacca gctagggctt tctgaaacca
    43441 ttcatgctct gtcgaacaat gattaagtac catgtccagc ataaagtcaa tcttgtgctc
    43501 tttaccgaca cataccattt cctcaaaatc agccatatca ccaaaaagag gatccactgc
    43561 catataatct gaaatatcgt aaccattatc ccgttgaggg cttggataga atggattgag
    43621 ccagaccata tccacaccta gtttggctaa atagggaatt ttttcgataa tcccacggaa
    43681 atccccaata ccgttttcag tggtgtcttt gtaagatttt ggatagattt gatagactac
    43741 ttttccttta tcaagtgtca tctgtttctc cttttctgat aaaagggagg aagcagtctt
    43801 ccgtccctat ttgtgctatt tcaattatac tcaatgaaaa tcaaagaaca aactaggaag
    43861 ctagccacag gttgctcaaa acactatttt gaagttgcag atagagctga cgtggtttga
    43921 agagattttc gaagagtatt agattcgtgt agcgaccatg agagatgctc cagcttggat
    43981 cgttgtcgga taagttccgg gaatagtcac tgtataagca tcttggttgg tgatgataac
    44041 aggagtttct gtcaccagac ctgcagcctt aatgacatcc atatcaaaac gaatcagttg
    44101 ctgaccaact gtaacgtgat ctccttggac tacaagactt tcaaaacctt tgccatcaag
    44161 acctactgta tccataccga tgtggatgag caattcaact ccctcgtcag agacaatgcc
    44221 gatggcatgc ttggtaggga aaagaaccgt cactgtccca ttaactggag aggtcaactc
    44281 accttggctt ggttcaatga ctagaccttg ccccatgaca cctgatgcaa aaataggatc
    44341 cgtcgcttga ctcaattctt tcacttggcc agttagtggg ctgataattt ctaccgaagt
    44401 aagttctact ggttcatggt tcacaaattc tgcttcttct tgagcaacga attctgcctg
    44461 caagttcgta tcgccctctg tttttgtaaa gagaccagcc ttgcggaaga agaaagtcaa
    44521 gagcattgga acaacaatcg caactagcat agttcctgca aatggcagca tgtattgagg
    44581 ttgaatagag agaatacctg gcaaaccacc gataccaata gaagccgcag ttacattaaa
    44641 agtaacggat aacatgcctg caagggctga accagtcatc ccagcaacaa atggataaat
    44701 atattttacg ttaaccccaa aaagagctgg ttctgtaaca ccgagatagg ctgaaatggt
    44761 tgcaggaagt gaaacctgag cctcacgctc atcatggcga tgcatgaaat aataggcaaa
    44821 cacggctgag ccttgagcaa tattagaaag agcaatcatt ggccataggg cagtgccacc
    44881 agcatccgca atcaattgtg tatcaatggc attggtcata tggtgcagac ctgtgatgac
    44941 aaatggagcg tagagggcgc caaaaattgc accgaagagc catttaactg gaccagttaa
    45001 acctgccaag acaactgatg aaagtccttg tccaattgtc caaccgattg gtcccaaaac
    45061 agtatgagcc aaaatcaagg ctggaatcaa tgacaagaaa ggtacaaaaa tcatagaaat
    45121 gacttctggg atatgcttgc gccagaagat ttcaagataa gacagactca aacctgcaag
    45181 caaggctggg ataacttggg cttggtaacc gatacgatta acagtaaaat agccaaaatt
    45241 ccaaacccag tttgccgcga tatcagctgc tggcgttgaa gcaaccgcat aggcattgag
    45301 caactgaggc gataccaaac agattccgag aacaattccc aaaatttggc tggttcccat
    45361 cttacgagaa acagaccaag taatccctac tggtaagaac tggaagatag cttcaccagg
    45421 caaccagagg aagtgattga cacctgccca aaactgagag gattctgtga tggtcttgcc
    45481 atccaacatc gaccaatgga caccttccaa gacattacgg aaaccgagga tcaatcctcc
    45541 gactatcaag gctggaataa tcggagtaaa aatctccgcc agagtggtca taacacgttg
    45601 gaccacgttt tgattactct tagctgcaga cttggctgct tctttggaaa caccctcaat
    45661 acctgaaacg gctgtaaaat cattataaaa gatgggcacg tcatttccaa tgattacctg
    45721 aaattgacct gcatttgtaa aggttccttt aacagctgga attgactcga tagctttaac
    45781 attagccttc ttatcatctc ctaaaacaaa ccgcatccgt gtcgcacagt gagttacggc
    45841 agtcacattt tctttgcctc cgattgcctg aagcagatct ttggcttctt gttcaaattt
    45901 tcccatttga ttctccttat acttgtcaaa gcaagtttga tttgataagt atattgtaaa
    45961 cgataccaaa cttgtctgca acttgtttgg tataaaaagg gtgttttttt gtaaattttc
    46021 tagcacttgt atggtaaaat agatacaggt gttcattaaa ctagactaaa aacctattta
    46081 agcaggcaaa atgaagaaat accaacaatt atttaagcaa atccaagaaa ccattcaaaa
    46141 cgagacttac gctgtcggag atttccttcc tagcgagcac gaccttatgg agcaatatca
    46201 agtgagtcgt gataccgtcc gaaaggccct gtctctcctc caagaggaag gattgatcaa
    46261 aaagataaga gggcaaggtt ctcaagtcgt caaagaagaa accgtcaatt tccctgtatc
    46321 caacctaacc agctaccaag aactagttaa agaacttgga ctgcgctcta aaaccaacgt
    46381 ggtcagtctg gacaagatta ttattgataa aaaatcctca ctgataaccg gtttcccaga
    46441 gtttcggatg gtttggaagg tggtccgcca gcgtgtggtg gatgatctgg tatccgttct
    46501 ggatacggac tatctggata tggaactcat cccaaatctc actcgccaaa ttgctgagca
    46561 gtctatctat tcttatatag aaaatggcct caaactcctt attgattatg ctcagaagga
    46621 aatcaccatt gaccactcaa gcgaccgaga caagattctc atggacattg gcaaagaccc
    46681 ttatgtcgtt tcgattaaat caaaagtcta tctccaagac ggacgccaat ttcagtttac
    46741 cgaaagtcgc cataagttag agaaatttag atttgtagat tttgcaaaac gcaagaaata
    46801 aaagactgag acaccagatc tcagcctttt tcggctctat aatatttgta gtgggtaacc
    46861 cccctatgga tattatggag cctattttgt gtagaaa
//
LOCUS       DBEJJE010000010        45597 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEJJE010000010 DBEJJE010000000
VERSION     DBEJJE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.10"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..147)
                     /locus_tag="ACL3F5_000577"
     CDS             complement(<1..147)
                     /locus_tag="ACL3F5_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0514428.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQ"
     gene            340..837
                     /locus_tag="ACL3F5_000578"
     CDS             340..837
                     /locus_tag="ACL3F5_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0514429.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            837..2492
                     /gene="dnaX"
                     /locus_tag="ACL3F5_000579"
     CDS             837..2492
                     /gene="dnaX"
                     /locus_tag="ACL3F5_000579"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0514430.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSTLDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2520..2714
                     /locus_tag="ACL3F5_000580"
     CDS             2520..2714
                     /locus_tag="ACL3F5_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0514431.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2864..3634
                     /gene="sufC"
                     /locus_tag="ACL3F5_000581"
     CDS             2864..3634
                     /gene="sufC"
                     /locus_tag="ACL3F5_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0514432.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3662..4924
                     /gene="sufD"
                     /locus_tag="ACL3F5_000582"
     CDS             3662..4924
                     /gene="sufD"
                     /locus_tag="ACL3F5_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0514433.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4935..6161
                     /locus_tag="ACL3F5_000583"
     CDS             4935..6161
                     /locus_tag="ACL3F5_000583"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0514434.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLAMALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6148..6588
                     /gene="sufU"
                     /locus_tag="ACL3F5_000584"
     CDS             6148..6588
                     /gene="sufU"
                     /locus_tag="ACL3F5_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0514435.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6641..8053
                     /gene="sufB"
                     /locus_tag="ACL3F5_000585"
     CDS             6641..8053
                     /gene="sufB"
                     /locus_tag="ACL3F5_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0514436.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8284..9525)
                     /gene="pbp3"
                     /locus_tag="ACL3F5_000586"
     CDS             complement(8284..9525)
                     /gene="pbp3"
                     /locus_tag="ACL3F5_000586"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0514437.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9628..10737
                     /gene="cozE"
                     /locus_tag="ACL3F5_000587"
     CDS             9628..10737
                     /gene="cozE"
                     /locus_tag="ACL3F5_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0514438.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLVNPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11383..11730
                     /gene="ssrA"
                     /locus_tag="ACL3F5_000588"
     tmRNA           11383..11730
                     /gene="ssrA"
                     /locus_tag="ACL3F5_000588"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11900..11987)
                     /locus_tag="ACL3F5_000589"
     tRNA            complement(11900..11987)
                     /locus_tag="ACL3F5_000589"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11951..11953),aa:Ser,seq:gga)
     gene            12149..12889
                     /locus_tag="ACL3F5_000590"
     CDS             12149..12889
                     /locus_tag="ACL3F5_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0514439.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12886..13797
                     /gene="pfkB"
                     /locus_tag="ACL3F5_000591"
     CDS             12886..13797
                     /gene="pfkB"
                     /locus_tag="ACL3F5_000591"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0514440.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRVDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13794..15746
                     /locus_tag="ACL3F5_000592"
     CDS             13794..15746
                     /locus_tag="ACL3F5_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0514441.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAL
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15883..18135
                     /locus_tag="ACL3F5_000593"
     CDS             15883..18135
                     /locus_tag="ACL3F5_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0514442.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFTGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     ADMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18180..18614)
                     /locus_tag="ACL3F5_000594"
     CDS             complement(18180..18614)
                     /locus_tag="ACL3F5_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0514443.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            18777..20861
                     /locus_tag="ACL3F5_000595"
     CDS             18777..20861
                     /locus_tag="ACL3F5_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0514444.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATYPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            20871..21248
                     /locus_tag="ACL3F5_000596"
     CDS             20871..21248
                     /locus_tag="ACL3F5_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514445.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHID
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            21408..22550
                     /locus_tag="ACL3F5_000597"
     CDS             21408..22550
                     /locus_tag="ACL3F5_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0514446.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            22559..23773
                     /gene="thiI"
                     /locus_tag="ACL3F5_000598"
     CDS             22559..23773
                     /gene="thiI"
                     /locus_tag="ACL3F5_000598"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0514447.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            23909..24733
                     /locus_tag="ACL3F5_000599"
     CDS             23909..24733
                     /locus_tag="ACL3F5_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0514448.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            24755..25494
                     /locus_tag="ACL3F5_000600"
                     /pseudo
     CDS             24755..25494
                     /locus_tag="ACL3F5_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            25507..26673
                     /locus_tag="ACL3F5_000601"
     CDS             25507..26673
                     /locus_tag="ACL3F5_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0514449.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASEFEPQYCLATSRRANAHYVY
                     SEENLLAKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE"
     gene            27181..28674
                     /locus_tag="ACL3F5_000602"
     CDS             27181..28674
                     /locus_tag="ACL3F5_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0514450.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGATDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            28687..29751
                     /locus_tag="ACL3F5_000603"
     CDS             28687..29751
                     /locus_tag="ACL3F5_000603"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0514451.1"
                     /translation="MKKVKLGEILSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQLAI
                     QKSLEELETLKKSLMQEYFG"
     gene            29811..30047
                     /locus_tag="ACL3F5_000604"
     CDS             29811..30047
                     /locus_tag="ACL3F5_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR0514452.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLQSGEIIFTPEE
                     LGQQVSHVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            30044..30457
                     /locus_tag="ACL3F5_000605"
     CDS             30044..30457
                     /locus_tag="ACL3F5_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR0514453.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            30575..31540
                     /gene="xerA"
                     /locus_tag="ACL3F5_000606"
     CDS             30575..31540
                     /gene="xerA"
                     /locus_tag="ACL3F5_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR0514454.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            31574..32680
                     /locus_tag="ACL3F5_000607"
     CDS             31574..32680
                     /locus_tag="ACL3F5_000607"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0514455.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            32710..36060
                     /locus_tag="ACL3F5_000608"
     CDS             32710..36060
                     /locus_tag="ACL3F5_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0514456.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTTVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(36646..37116)
                     /locus_tag="ACL3F5_000609"
     CDS             complement(36646..37116)
                     /locus_tag="ACL3F5_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0514457.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(37133..39406)
                     /locus_tag="ACL3F5_000610"
     CDS             complement(37133..39406)
                     /locus_tag="ACL3F5_000610"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0514458.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            39753..42854
                     /locus_tag="ACL3F5_000611"
     CDS             39753..42854
                     /locus_tag="ACL3F5_000611"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0514459.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVKKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            42937..43944
                     /gene="pfkA"
                     /locus_tag="ACL3F5_000612"
     CDS             42937..43944
                     /gene="pfkA"
                     /locus_tag="ACL3F5_000612"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0514460.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGGIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            44003..45508
                     /gene="pyk"
                     /locus_tag="ACL3F5_000613"
     CDS             44003..45508
                     /gene="pyk"
                     /locus_tag="ACL3F5_000613"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0514461.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT        14043 a         7991 c         9830 g        13733 t
ORIGIN      
        1 ttggtttccg cactcagggc aagatggggc gtcgtagtcc agtttggcga tgatttcctt
       61 gtgtgtatcc ttattgatga tgtctaaaat cttgatgttt gggtctttaa tgtctagtaa
      121 ttttgtgata aaatgtaatt gttccatatg aatctttcta atgagttgtt ttgtcgcttt
      181 tcattatagg tcatatggga cttttttcta caaaaaaata ggctccataa tatccatagg
      241 ggatttaccc actacaaata ttatagagcc caaaatcctt tgtttactaa acaagggatt
      301 tttcttttgt ctctgctcct tttttgatat aatagttcta tgttaaaatc agaaaaacaa
      361 tcacgttatc aaatgttaaa tgaagaattg tccttcctat tggaaggcga aaccaatgtt
      421 ttggctaatc tttccaacgc cagtgctctc ataaaatcac gttttcctaa taccgtattt
      481 gcaggctttt atttgttcga tggaaaggaa ttggttttag gtcccttcca aggaggtgtt
      541 tcctgcatcc gtattgcact aggcaagggt gtttgtggtg aggcagctca ctttcaggaa
      601 actgttattg ttggagatgt gacgacctat ctcaactata tttcttgtga tagtctagct
      661 aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt tacttggagt tctggatctg
      721 gattcttcag agattgagga ttacgatgct atggatcgag attatttgga acaatttgtc
      781 gctattttgc ttgaaaagac agcatgggac tttacgatgt ttgaggaaaa atcttaatgt
      841 atcaagcact ttatcgaaaa tatagaagtc aaaacttctc ccagttagtt ggtcaagaag
      901 ttgtggctaa gactcttaaa caagcggtgg agcaagagaa aataagtcac gcttatcttt
      961 tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa aatctttgcc aaggctatga
     1021 actgtcccaa tcaagtgggt ggcgaacctt gcaataactg ctatatttgt caagcagtga
     1081 cggacggtag tttagaagat gtcattgaaa tggatgcagc ttctaataat ggggtagatg
     1141 aaattcgcga aattcgtgat aaatctacct atgcgcctag ccttgctcgt tataaggttt
     1201 atatcataga tgaggttcac atgctgtcta caggggcttt taatgccctc ctaaagacgc
     1261 tggaagaacc aacacagaat gtagtcttta ttttggccac tactgaattg cacaagattc
     1321 ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa atcaattaag acacaggata
     1381 ttaaggaaca tattcactat atcttagaaa aagaaaatat cagttctgaa ccagaggctg
     1441 tggaaatcat tgccagacgg gcggaaggtg gaatgcggga cgccttgtct attttggatc
     1501 aagccctgag tttgacacag ggaaatgagc tgacgactgc tatctctgaa gaaattactg
     1561 gcaccattag cctatcaacc ttggatgatt atgtggcggc cttgtctcaa caggatgttc
     1621 ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg taagagcatg actcgttttg
     1681 tgaccgatct tttgcactat ttaagagact tgttaattgt tcaaacaggg ggagaaaata
     1741 ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc tcaaaaaaat ctgtttgaaa
     1801 tgattcgctt agcaacagtg agtttagcag atattaagtc tagtttgcag cccaagattt
     1861 atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc cgaaccagct ctatcaggag
     1921 cggttgaaaa tgaaattgct acgctgagac aggaagttgc ccgtctcaaa caagagcttt
     1981 ctaatgcagg tgcggttcct aaacaagttg caccagctcc tagtcgacca gctacgggca
     2041 aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat cttacaagag gccgtcgaaa
     2101 atcctgattt agcacgtcaa aatctaattc gtttgcagaa tgcctgggga gaggtaattg
     2161 aaagtctagg tgggccggac aaggctctgc tagttggttc tcaaccggtt gctgccaatg
     2221 aacaccatgc tattcttgct tttgagtcta acttcaatgc tggtcaaact atgaaacgag
     2281 acaatctcaa taccatgttt ggtaatatcc tcagtcaggc ggcaggtttt tcacctgaga
     2341 ttttagctat ttccatggag gaatggaaag aagttcgcgc agccttttca gccaaagcca
     2401 aatcttctca aactgaaaaa gaagtagaag aaagcctgat tccagaagga tttgaatttt
     2461 tggctgataa agtgaaggta gaggaagact aaagaaagat ttcatgatac aataagttta
     2521 tgaataaaca acaatttatt attatggcgc tatttacagc tgctgagacc tattttttca
     2581 atgaagcctg gatgactggc cgctatatta tggcagcctt ttgggcaatt ttactcttta
     2641 gaaatttccg agtcagttat gtgatgggta aaatcgttga tgtcatcgat cagcatttta
     2701 ataggaaaga ctagccctca gcttccagac aaaatcaaag ccttttaggc ttttttttgt
     2761 tatactagaa aagtatattt atagaatttt tgctctattt ctggggaaat cagacgtttt
     2821 tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact atcatgtcag taatagagat
     2881 caaagatctt cacgttgaga ttgaaggaaa agaaatttta aaaggggtta acctgaccct
     2941 gaaaacagga gaaattgccg ctatcatggg accaaatggt acaggtaaat cgactctttc
     3001 tgccgctatc atgggaaatc caaactatga agtaactaaa ggtgaagttt tgtttgatgg
     3061 cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt atgggacttt tccttgctat
     3121 gcaataccca tcagaaatcc ctggaattac caatgctgag tttcttcgtg ccgctatgaa
     3181 tgcgggtaaa gaagatgatg agaagatttc agttcgtgag tttattacta agctagatga
     3241 aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag cgttacctca acgaaggctt
     3301 ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt ttgatgttgg agccaacatt
     3361 tgctcttttg gacgagattg actcaggtct tgatattgac gctcttaaag ttgtgtctaa
     3421 aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg atcatcactc actaccaacg
     3481 tcttttgaac tatatcacac ctgatgtggt acacgtgatg atggaaggtc gtgttgtcct
     3541 ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa ggatacgcaa aattagctga
     3601 agaacttggc tacgactaca aggaagaatt gtaattccct cgtatctttt aggagaagta
     3661 aatgactaga gaaaatatta aacttttttc agaaatgcac gctgaaccaa gctggttggc
     3721 tgatctccgt caaaaagctt ttgacaagat tgagactttg gaattaccag ttattgagcg
     3781 tgtcaaattc caccgttgga atctgggtga tggaacgatt acagaaaatg agccatcagc
     3841 aaatgttcca gatttcacag ctttagatca tcacttgaag ttggtgcaag taggaactca
     3901 aactgttttc gaacaaactc cagttgagtt agctgaacag ggtgttgtct tcacagactt
     3961 tcactcagct ttagaagaaa ttccagagct gatcgaagaa ttcttcatgt catctgttaa
     4021 gtatgatgat gacaagttgg cggcttacca cacagcttac tttaacagtg gtgctgtact
     4081 ctatattcca gataacgtag aaattacaga gccaattgaa ggaattttct accaagatag
     4141 tgatagcaat gtgccgttta acaagcatat tatgattatc gctggtaaaa attctaagat
     4201 tagttatctg gagcgtttag agtcacgcgg tgaaggaagt gacaaagcaa ctgccaatat
     4261 cacagtggaa gtgattgcac gttctggtgc gcaagtcaag tttgctgcta tcgaccgtct
     4321 aggtgaaaac gtcactgcct acattagccg tcgtggtaaa ttaggcaacg atgcaagtat
     4381 tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt gctgattttg atagtgactt
     4441 gattggtaat ggtagccatg ctgacctcaa ggttgtagct ctttcaagtg gtcgtcaggt
     4501 acaagggatt gatactcgtg taactaacta tggctgcaac tcaatcggaa acattctaca
     4561 acatggggtt atccttgaaa aagcaacttt gactttcaat ggtatcggcc acatcatcaa
     4621 gggtgctaag ggagcagatg cgcaacaaga gagccgtgtt ctcatgcttt cagaccaagc
     4681 gcgttcagat gctaacccaa ttcttttgat tgatgaaaat gacgtaactg caggacatgc
     4741 agcctctatt ggtcaggtag atccagaaga catgtattac ctcatgagtc gtggattgga
     4801 taaggcaact gcagagcgtt tggttgttcg tggtttcctt ggatctgtta tcgtggagat
     4861 tccagtcaag gaagttcgtg atgaaatgat tgcaactatc gaagagaaat tgtcaaaacg
     4921 ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa ggattttcca attttagatc
     4981 agattgtcaa tgatgaacct ctggtctatc tggacaatgc tgcgacgaca caaaaaccac
     5041 tagtagttct gaaagctatt aacagctact atgagcagga caatgccaat gttcaccgtg
     5101 gtgtccatac cttagcggaa cgagcgacag cttcttatga agctgctcgt gaaaccattc
     5161 gtaagtttat taatgcaggc tctacaaagg aagttctctt taccagagga acgacaacca
     5221 gccttaactg ggtggcacgc tttgctgagg aaattctcgc tgagggagac caggtcttga
     5281 tttcagtaat ggaacaccat tctaatatca ttccatggca ggaagcttgt cgaaagactg
     5341 gagcagagct tgtctatgtc tatcttaaag acggtgcctt ggatatggag gatttgcgag
     5401 ctaaattgac tgataaggtt aaatttgttt ccctagctca tgcctccaat gttcttggtg
     5461 tggtcaatcc gatcaaggaa atcactcaat tagcccacca agttggggca attatggtag
     5521 tggatggtgc tcaatctaca cctcatatga agattgatgt ccaggacttg gatctggact
     5581 ttttcgcctt ttcgggtcac aagatggctg gtccgactgg tatcggtgtc ctttacggca
     5641 aagaaaagta tcttgagcaa atgtctccag tagaatttgg cggcgagatg attgattttg
     5701 tctacgagca atttgctagt tggaaggaat taccttggaa atttgaggct ggaacgccaa
     5761 atatggcagg agctattgga cttgcgactg cagttgatta tctggaaaag attggtatgg
     5821 atgccgttga agctcatgaa caggaattga ttgcgtacgt ctatccaaaa ctgcaggcaa
     5881 ttgagggatt gaccatttac ggttctcagg atttggctca acgttcgggt gttattgcct
     5941 ttaacctagg tgatctccat cctcacgatc ttgcgatggc tctggattat gaaggagtgg
     6001 ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca gtatttggaa gtcccagcaa
     6061 cagctcgtgc aagtttttat atctacaata ccaaggcaga ttgcgacaaa ctagtcgatg
     6121 ccctacaaaa gacaaaggag tttttcaatg gcactttcta aactagatag cctttatatg
     6181 gcagtggtag cagaccattc gaaaaatcca catcaccaag ggaagttaga agatgctgag
     6241 caaatcagtc tcaacaatcc gacttgtggg gatgtcatca acctctctgt caagtttgat
     6301 gcagaggacc gtttggaaga tattgctttt ctaaattcag gatgcacgat ttcaactgct
     6361 tctgctagta tgatgacaga tgccgtttta ggaaaaacca aacaagaaat tttagaactg
     6421 gcgactattt tttctgaaat ggttcaaggg caaaaagatg agcgtcaagg ccaacttgga
     6481 gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa gaatcaagtg tgcaacccta
     6541 gcttggaatg cccttaagaa aacaattgaa aatcaagaaa aacagtagac aagtttcttt
     6601 tgtcttatga attattagaa atgaagaaag aaaggatact atggctgaag aaagagtaga
     6661 accaaaacca attgaccttg gtgaatataa atttggtttc catgacgatg tagagcctgt
     6721 cttatcgaca ggaaaaggac tcaacgaagg tgttattcgt gaattatctg ctgctaaggg
     6781 tgagcctgag tggatgttgg agttccgttt gaagtcttat gaaaccttca aaaaaatgcc
     6841 catgcaaact tggggagcag acttgtcaga gattgacttt gatgacttaa tctactacca
     6901 aaaaccatct gacaaaccag cccgttcttg ggatgatgta cctgaaaaga ttaaagaaac
     6961 ctttgaacgt atcgggattc cagaagctga acgtgcttat ttagcagggg cttctgccca
     7021 gtacgagtca gaagtggttt accacaacat gaaggaagag ttccaaaaat taggtattat
     7081 ctttacagat acagattccg cactcaagga atacccagac ttatttaaac aatactttgc
     7141 gaagttggta ccgccgacag ataacaagtt ggcagccctc aactcagcag tatggtcggg
     7201 tggaactttt atctacgtgc caaaaggtgt caaggtagat attccacttc aaacttattt
     7261 ccgtatcaat aacgaaaata taggtcagtt cgaacgtacc ttgattatcg ttgatgaggg
     7321 agcaagcgtc cactacgtag aaggatgtac agcaccaaca tattcaagca atagcttaca
     7381 cgctgccatt gtagaaattt ttgctttgga cggagcttat atgcgttata caactatcca
     7441 aaactggtct gataacgtct ataacttggt aacaaagcgt gctaaggctc aaaaggatgc
     7501 cactgttgag tggattgatg gaaacttggg tgccaaaacg actatgaaat atccatctgt
     7561 ttaccttgat ggagaaggag cgcgtggtac catgctctct atcgcctttg ctaatgcagg
     7621 gcaacaccaa gacacgggtg ctaagatgat tcacaatgct ccacatacca gctcgtctat
     7681 tgtgtctaaa tccatcgcta aaggtggagg aaaggttgac taccgtggac aagtcacctt
     7741 taacaagaac tctaagaaat ctgtttccca cattgaatgt gataccatta tcatggatga
     7801 cttgtcagca tcagatacta ttccatttaa tgaaattcac aactcgcaag tggctttgga
     7861 acacgaagcc aaagtatcta agatttcaga agagcaattg tattatctca tgagccgtgg
     7921 attgtcagaa tctgaggcaa ctgaaatgat tgtcatggga tttgtagaac cctttacaaa
     7981 agaacttcca atggaatacg cagttgagct gaaccgcttg attagctatg aaatggaggg
     8041 atcagttgga taaaatttga ttttatactc ttcgaaaatc tcttcaaacc acgtcagcat
     8101 cgccttaccg tatgtatggt tactgacttc gtcagtttca tctacaacct caaaacagtg
     8161 ttttgagcaa cctgcggcta gcttcctagt ttgttctttg attttgagta ttagatttac
     8221 tcaaaatcaa ggattttgaa gatgaacttg tatcaaaaaa tcgcggttta aaatcgcgat
     8281 tttttataat ttctcgttaa caaagcggac aaactgattc caccaaactt ttaagaagaa
     8341 ggctttttca attttcttgt ctgctaccat ttcgaaacta gggcgctctg tggtgatgta
     8401 accttgacca atcaagtcct tgtcttcata agtcaaatgg ccaaccactg ttccagcttc
     8461 aagtggtgct gggattgctt tggaatcagg tgtgaattga acagattggg aagattgatt
     8521 cccaacacgt tctattagat agatatcctc tggagccact gcagttactg tatcttcttt
     8581 tccatcttgt acaggggctt tgctatcttg ataggcatcg ccttgttgaa cgattttgcg
     8641 aagtgtaaat gtagaagaaa tataatccat tagggaagat gtagctgtaa atcgagcgta
     8701 aggattattg tcttgatgat ctgcatttaa aacaactgtg atgactctca tgcctttttc
     8761 gacagtagta ccaacaaaag actctccagc cttatctgtt gttcctgttt ttagcccatc
     8821 aaaaccacca cggtaagcag gcataccttc taacatgtag ttggttgaag tgattgtcat
     8881 cccagcaaaa gtagaagaag gttttttggt gatttctaag acttgtgggt attttttgat
     8941 gaggttgcga gcaacgatag cgacatcata agcactaagc ttattttcct catctttttt
     9001 agaacctggg taaatgttat cccctagagt ttcattgtta agacctgtcg tattgacaac
     9061 agtggcatcc tgaattcccc attccaagag ttttgcccgc atcatatcga cgaaatcttt
     9121 ttctgagcca gcaattttct cagctagggc aatagcggcg ctgttggcac tagataccag
     9181 agttgcttca agcaactctt cgacagtata attacgggcc tccataggaa tattactggc
     9241 ttcagaattt gtcgtcaatt gataaggata atcagaaata tctacaggag tggagagggt
     9301 aatacttccg ttttccaaag cttcatagac cagataaaca gtaatcaatt ttgttatgga
     9361 agcaatttcg acaggttgcg ttgcatcctt ctcatagaga attttaccag tatttgcctc
     9421 aacagcaatc gcatgtttag cggcaatggt aaaatcttga gcaacagcag tagaagcacc
     9481 ccctaaaaga gagacagtta ataaagttaa aaatattttt ttcatagtag tcttattcta
     9541 tcataaagaa aaaaaatatt cttgctttaa taattcatct gttaagcttt ttgaaaatat
     9601 ggtaaaataa agtaagggag gtaactcatg tttcgtagaa ataaattatt tttttggacc
     9661 acagaaattt tactcttaac catcatcttt tacctatgga gacagatggg gtctttggtt
     9721 aacccttttg ttagcgtgct taatacaatt atgattccat ttttattagg gggctttctt
     9781 tattatttga caaaccctat tgttactttc ttaaataaag tctgtaaact caatcgtttg
     9841 cttggtattt taattacctt gtgtactttg gtctggggaa tggtcatagg tgttgtctat
     9901 ctcttaccta ttttgattaa tcagttatct agtttgatta tatctagtca aactatttat
     9961 agtcgagtac aagacttaat catagactta tctaattatc ctgcgctcca gaatttggat
    10021 gtagaagcta caattcagca gttaaactta tcctatgtgg atattcttca aaatatccta
    10081 aatagcgtat caaatagtgt ggggagcgtc ttgtcagctc ttatcagtac tgttttgatt
    10141 ttgattatga ctccagtttt tttggtttat ttcttattag atggacataa attcttaccc
    10201 atgcttgaaa gaacgattct aaagagggat cgcttgcata ttgcaggctt attaaagaat
    10261 ttaaatgcga cgattgctcg ctatattagt ggagtttcga ttgacgcaat cattataggt
    10321 tgtttagctt atattggcta tagtattatt ggtttaaaat atgctttagt ttttgccatt
    10381 ttttctggtg tagccaattt aattccttat gtggggccaa gtattggttt gattcctatg
    10441 atcatcgcaa atatattcac tgatccccat agactgctga ttgcagtgat ttatatgctt
    10501 gttgttcagc aggtagatgg caatatctta tatcctcgaa tcgtaggaag tgttatgaag
    10561 gttcatccaa tcacgatttt agttttactt ttgttgtcaa gcaatatcta tggtgtagtt
    10621 ggaatgattg tcgcagtgcc aacctattct atcttgaaag aaatttctaa gttcttatcc
    10681 cgtttgtatg aaaatcataa aataatgaaa gaacgagaaa gagaattagc taagtaaaag
    10741 tcaggagaac cctgattttt ctttactgga agtggccttt agattagaag actgaaaata
    10801 agttaaagtc ttaaactaat tttcacagct aagaatagta gaagttaatc tgataaaaat
    10861 cgaaaaaacc agtggaattc cgtgtcaggg taagttccac tggttttcat agtctattaa
    10921 agttcgaatg aaacctattt atagtatatt gaaactagaa tagtacacct ctaattctaa
    10981 aacattgtta gaaatcgatt tgactgtcct gatctattca tcctattctt atttcatttt
    11041 actatatttt ggtgcaataa gtgaaaagta gtccgaataa tataaggatt aattttatag
    11101 tttttaaact caaatgaatt aaaataaaga gagtacgaaa attctcatct gaaagtattt
    11161 tagaataatt ctcttcgtga atttcttcaa aacagatagc ttcatcttag gtatgtgtta
    11221 attggatttc gtaagctcta tttacaatcg taaagttatg cactgagaaa gttgtagtta
    11281 gtcttccagt ttgctaaatt tctcgaatag tatctttttt aggtatgtga tttctttttg
    11341 catttttgag ttagataagg tataatggtt ttattgtctt ttggggtcgt tacggattcg
    11401 acaggcatta tgaggcatat tttgcgactc gtgtggcgac gtaaacgctc agttaaatat
    11461 aactgcaaaa aataacactt cttacgctct agctgcctaa aaaccagcag gcgtgacccg
    11521 atttggattg ctcgtgttca atgacaggtc ttattattag cgagatacga ttaagccttg
    11581 tctagcggct tgataagaga ttgatagact cgcagtttct aggcttgagt tatgtgtcga
    11641 ggggctgtta aaataataca taacctatgg ttgtagacaa atatgttggc aggtgtttgg
    11701 acgtgggttc gactcccacc ggctccatta ttcctttgca ttcttttgca ttccttggta
    11761 aaacgttgtt aaatcaacgt tttttatttt tatctttggt attcctttgc attcttttgc
    11821 taaaaaggga gtcacaaaca gaccctattt taaaaaagga tacaacattt gttgcatcct
    11881 aaaaataatc ttttttcgac ggaagacatg ggattcgaac ccacgcacgc tattacacgc
    11941 ctaccgcgtt tccaacacgg cctcttaagc ctcttgagta atcttccaat acttacttaa
    12001 atagtctacc ataaaggctc ttatcttgca ataaaaattc tagaaataag aaaaatgata
    12061 gattttgaaa gaaaatgata aaaaatgctt gacttcgaaa taaagtatgg tagaatgaat
    12121 agtgtaaacg ataacaggag gtgattcagt gttaaaaaca gaacgtaaac aactgatttt
    12181 agaggagtta aatcaacatc atgtagtttc tctagaaaaa ttagttagtt tgctagaaac
    12241 gtcagaatca acggttcgaa gagacttgga tgagttggaa gcggaaaaca agcttcgtcg
    12301 tgtgcatggt ggagcagaac tcccccactc cttacaggaa gaagaaacca ttcaagaaaa
    12361 atctgtcaaa aaccttcaag aaaagaagtt gctggctcag aaagcagcct ctctcattaa
    12421 agaaaaagat gtcatcttta tcgatgctgg aacaacaact gcttttttga ttcatgaatt
    12481 ggtcaataag aatgttacag ttgtgaccaa ctccattcac catgccgctc agttggttga
    12541 aaagcagatt ccaactgtca tggttggagg aaacgtcaag acggcgacag atgctagtat
    12601 cgggggcgtt gctcttaacc agattaacca attgcacttt gaccgtgcct ttatcggaat
    12661 gaatggtgtt gacgatggct attatacgac tcctgatatg gaggagggag ctgtgaaaag
    12721 agctattttg gagaatgcca agcagaccta cgtcttggtg gattcgtcaa aaattggaca
    12781 aacttgcttt gccaaggtag caccactcaa acgcgctatc gttatcacta gtcaagggca
    12841 tgagctcttg caggttatta aggagaaaac ggaggtaata gaagtatgat ttatacagtc
    12901 acactcaatc catccattga ctatatcgtt cgtttggacc aagtcaaagt tggtagtgta
    12961 aatcgtgtgg acagtgatga taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc
    13021 ttgaaacgtt tgaatatacc aaatacagcg acgggattta tcggtggctt tactggtaaa
    13081 tttatcacag atactttagc agaggaagaa atcgagacac gttttgtcca ggtggcagaa
    13141 gatactcgta tcaatgttaa aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt
    13201 ccaactgttg aaccggttca gctagaagaa ttgaaagcta ttttatctag tctgacagca
    13261 gaagatacag ttgtctttgc aggttcaagt gctaaaaatc taggcaatgt tatctataag
    13321 gatttgattt ccttgacgcg ccagactggt gcgcaagtgg tctgtgactt tgaaggacag
    13381 accttaattg atagtttgga ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt
    13441 ggagcgattt ttggggttaa actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag
    13501 ttactggcta agggtgctca aaatgttatt atctctatgg ctggtgatgg cgcccttctt
    13561 gtcacatctg agggagctta cttcgctaaa ccaatcaaag gaacagtcaa aaattcagtt
    13621 ggagctggtg attctatggt tgctggattc acaggtgaat ttgtcaaatc aaaagacgca
    13681 gtagaagcct tcaaatgggg agtggcttgc ggaacggcaa ctaccttctc agatgacttg
    13741 gcaacggcgg aatttattaa agaaacatat ggaaaagttg aggtagaaaa aagatgaaaa
    13801 ttcaagacct attgagaaaa gatgtcatgt tgctagattt gcaggcaact gaaaaaacag
    13861 ctgtcatcga cgagatgatt aaaaatttga cagagcacgg ttatgtaaca gattttgaaa
    13921 catttaaaga aggaattttg gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa
    13981 tcgcaatgcc tcacagcaaa aacgctgctg tcaaagaagc gacagttcta tttgctaagt
    14041 caaataaggg tgttgactac gagagcttgg atggacaagc aactgacctc ttcttcatga
    14101 ttgcagctcc agaaggtgcc aatgatactc acttggcagc cttggcagaa ttgtctcaat
    14161 acttgatgaa agacggtttt gcagacaaac ttcgtcaagc aacatctgca gaccaagtta
    14221 tcgaactttt tgaccaagct tcagaaaaaa ctgaggaact tgttcaagca cttgctaatg
    14281 actctggtga ctttatcgta gctgttacag cttgtacaac aggtattgcc cacacttaca
    14341 tggcccaaga agcccttcaa aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa
    14401 ccaacggtgc tagcggtgtt ggaaatcaac taactgcaga agatatccgt aaggctaaag
    14461 ctattatcat tgcagcagac aaggccgttg aaatggatcg atttgatgga aaaccattga
    14521 tcaatcgtcc agttgctgac ggtatccgta agacagaaga gctaattaac ttggctcttt
    14581 caggagatac tgaagtctac cgtgccgcta atggtgcaaa agctgcaaca gcctctaacg
    14641 aaaaacaaag ccttggtggt gccttctaca aacacttgat gagtggtgta tctcaaatgt
    14701 taccattcgt tatcggtggt ggtatcatga ttgcccttgc cttcttgatt gacggtgctt
    14761 tgggtgttcc aaatgaaaac cttggcaatc ttggttctta ccatgagtta gcttctatgt
    14821 tcatgaaaat tggtggagct gcctttggtt tgatgcttcc agtctttgcg ggttatgttg
    14881 cctactctat tgctgaaaaa ccgggtttgg tagcaggttt cgtggctggt gctattgcca
    14941 aagaaggttt tgcctttggt aaaattcctt atgccgcagg tggtgaagca acttcaactc
    15001 ttgcaggtgt ctcatctggt ttcctaggtg cccttgttgg tggatttatc gcaggtgcct
    15061 tggttcttgc catcaagaaa tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa
    15121 tccttctatt gccacttctt ggaacaatct tgacaggatt tgttatgcta gctgtgaata
    15181 tcccaatggc tgcaatcaac actgctatga atgacttcct aggcggtctt ggaggaggtt
    15241 cagctgtcct tcttggtatc gtccttggtg gaatgatggc tgttgacatg ggtggaccag
    15301 ttaataaagc agcttatgtc tttggtacag gtacgcttgc agcaactgtt tcttcaggtg
    15361 gttctgtagc catggcagca gttatggctg gaggaatggt gccaccactt gcaatctttg
    15421 tcgcaactct tcttttcaaa gataaattta ctaaggaaga acgtaactct ggtttgacaa
    15481 acatcatcat gggcttgtca tttatcactg agggagcgat tccatttggt gccgctgacc
    15541 cagctcgtgc gattccaagc ttcatccttg gttcagcagt agcaggtgga ctcgttggtc
    15601 ttactggtat caaactcatg gcgccacacg gaggaatctt cgttatcgcc cttacttcaa
    15661 atgctctcct ttacctcgtt tctgtcttgg taggagcaat cgtaagtggt gtggtttatg
    15721 gttacctacg caaaccacaa gcataaaaaa tagaaaaatg aaaagattgg accgtttggt
    15781 gcagtctttt tctcttcccg aaatgcctgt gaaatatggt ataatagaag aatggcaaac
    15841 aagaatacaa gtacaacaag acggagaccg tctaaagcag aactggaaag aaaagaagcg
    15901 attcaacgaa tgttgatttc gttaggaatt gcgattttat tgattttcgc agccttcaaa
    15961 ttaggggctg caggtataac cctttataat ttaattcgct tgctagtggg tagcctagct
    16021 tatctggcga tattcggcct attaatctat ctcttctttt tcaagtggat acgaaaacag
    16081 gaaggactct tatctggctt tttcaccata tttactggct tactcttgat ttttgaggcc
    16141 tacttggttt ggaaatatgg tttggacaag tccgttctaa aagggaccat ggctcaggtt
    16201 gtgacagatc tgactggttt tcgaacgact agctttgctg gagggggctt gatcggggtc
    16261 gctctttata ttccaacagc ctttctcttt tcaaatatcg gaacttactt tattggttct
    16321 atcttgattt tagtgggttc tctcctagtc agcccttggt ctgtttacga tattgctgaa
    16381 tttttcagta gaggctttgc caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc
    16441 tttgtcaaac aagaagaaaa agctcgccaa aaggctgaga aagaggctag attagaacaa
    16501 gaagagactg aaaaagcctt actcgatttg cctcctgctg atatggaaac gggtgaaatt
    16561 ctgacagagg aagctgttca aaatcttcca cctattccag aagaaaagtg ggtggaacca
    16621 gaaatcatcc tgcctcaagc tgaacttaaa ttccctgaac aggaagatga ctcagatgac
    16681 gaagatgttc aggtcgattt ttcagccaaa gaagcccttg aatacaaact tccaagctta
    16741 caactctttg caccagataa accaaaagat cagtctaaag agaagaaaat tgtcagagaa
    16801 aatatcaaaa tcttagaagc aacctttgct agctttggta ttaaggtaac agttgaacgg
    16861 gccgaaattg ggccatcagt gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc
    16921 aaccgcattt ccaatctatc agatgacctc gctctagcct tggctgccaa agatgtccga
    16981 attgaagcac caatccctgg gaaatcccta atcggaattg aagtgcccaa ctccgatatt
    17041 gccactgtat ctttccgaga actatgggaa caatcgcaaa cgaaagcaga aaatttcttg
    17101 gaaattcctt tagggaaggc tgttaatgga accgcaagag cttttgacct ttctaaaatg
    17161 ccccacttgc tagttgcagg ttcaacgggt tcagggaagt cagtagcagt taacggcatt
    17221 attgctagca ttctcatgaa ggcgagacca gatcaagtta aatttatgat ggtcgatccc
    17281 aagatggttg agttatctgt ttacaatgat attccccacc tcttgattcc agtcgtgacc
    17341 aatccacgta aagccagcaa ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat
    17401 gaactctttg ccaaggtggg agttcggaat attgcaggtt ttaatgccaa ggtagaagag
    17461 ttcaattccc agtctgagta caagcaaatt ccgctaccat tcattgtcgt gattgtggat
    17521 gagttggctg acctcatgat ggtggccagc aaggaagtgg aagatgctat catccgtctt
    17581 gggcagaagg cgcgtgctgc aggtatccac atgattcttg caactcagcg tccatctgtt
    17641 gatgtcatct ctggtttgat taaggccaat gttccatctc gtgtagcatt tgcggtttca
    17701 tcaggaacag actcccgtac gattttggat gaaaatggag cagaaaaact tcttggtcga
    17761 ggagacatgc tctttaaacc gattgatgaa aatcatccag ttcgtctcca aggctccttt
    17821 atctcggatg acgatgttga gcgcattgtg aacttcatca agactcaggc agatgcagac
    17881 tacgatgaga gttttgatcc aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga
    17941 gatgctggtg gtgatccgct ttttgaagaa gctaagtctt tggttatcga aacacagaaa
    18001 gccagtgcat ccatgattca gcgtcgtttg tcagttggat ttaaccgtgc gacccgtctc
    18061 atggaagagc ttgagatggc aggtgtcatt ggtccagctg aaggtaccaa accaagaaaa
    18121 gttttacaac aataaaaaaa tagcttcttt ccaagtttgg aaggaggcta ttttagtgat
    18181 tattgattag ttttattttc cgaagttggg gtattggact gtttttcgtt ttcagtagca
    18241 ggtttacttg gagtaggagc aggagtagaa gaatcctgag ttgatgtttt ctgctcttct
    18301 tttttctctt ccttgacgct ggattttggc gtttcttctt gttgtgtttt ttcttgagaa
    18361 gtcttatttt ccttattggg actagtattt tcctgagggg attccttttg aatttctttg
    18421 acaattgttg tcgtctggct tgttgtaggt tcctttttag tatttttgtt attatccaag
    18481 gcgttcataa tcgtgatact agcggtaatc aagccaagga tactagcgat agtcgcaacg
    18541 gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt tgaagttcta
    18601 cgataattag acatacattc tctcctttaa ttaaaattta ttatacctca tttctttaaa
    18661 aaaatcttaa aaaaagagga gatttttcta cacgaacttc agtaattagt tgaaataaaa
    18721 tatgacttat gatataacaa aataaagaaa gcgatttcaa aaaaggaggg cgttatatgt
    18781 tcgaaattag aaatttgagt ctctcttttg caggcaggcg gttgctagag ccaacagatt
    18841 tgatatttga aaggggaaaa gtatatacaa tatatgggaa gtcaggcgta ggaaagtctt
    18901 ctttactgaa taaaattggt ttgctctctg ctacgtatcc tagtgtttct tatttcttcg
    18961 atggaaaaga gattgatatc gaaaataaga aatcagtctc tgtctttata gctgaagaag
    19021 ttgcctttgt atttcagggg cgaaatctaa taaatgattt gaccgtattt gaaaatttaa
    19081 gactagcttt aaacttttat gacttgagtc cagatgaaat agaaagcaaa attgatacag
    19141 tattggcgga tttacagatt tcttctttaa agcatgctta tccagaagat ttatccggtg
    19201 gtgaagaaca acgagtggca atcgcaagag ccttagttac aggaaagact ctcatcttag
    19261 ctgatgaacc aacaagttct ttggataaag aaaatagaga aaaagtctcc gccttgttaa
    19321 ttgatttagc tcacaaatat cataaaattg tattgattgt ttcgcatgat gaggcgatga
    19381 ttgcaatagg agatgttcag cttcatttta aagaccataa attagttggg aattgtctta
    19441 ttttgaattc tgatgaaggg ataaaggatt ctaagaagtg gtcctcctgt ttgtcgtctt
    19501 ctcatacgaa gctatccgtt ttgaaacata gaaggccttt tttacctaga ttattagcgt
    19561 tttttatctc tcttgtagtt gctatagcag taacctctat taactttcag tccttatttg
    19621 cagataagta tcaccaactg gtgaacaact cactcgaaaa tggcttcttg gtgattaatg
    19681 attcgcttca tttacaaact acaaaagtgt tggatgattt tctcagtttt gataaggagg
    19741 aaatcacctc aattagcaca agtcagaata ttcaaaccgt caatccttat atagagtttc
    19801 tctctttggg tatgacgttt gataattcaa aagactattc acaacttcaa aagaactttc
    19861 agccaacttt gactattgat ggtcagacca gaagcttgac aagaaatttt tcaattcaac
    19921 ccttgtatca gacaaataca acacagaggc agatagagta ttttgatagg agcaatgaaa
    19981 aagggattta tctatctgag caattcattt cagatgaaaa attaccaaat atagtttcgg
    20041 gaactaccgt gacactgact ttttatattc caatttcttt atatgaatca agtatagaga
    20101 aagaggggaa tatattgaaa ggagatggcg atttatttgt caaagtggat aaaacatatc
    20161 ctgttttagg gattgttaaa aaaagttatc cgtttgaata ttccccttat gggaacaccc
    20221 tatttatgaa tattgctgaa atggaagaat tgcaaaatga agcaattcaa cagcatccca
    20281 tgacgaagat ggctttagat ggttttcctt tgaaatcatg gatgccgagt gcgattcatg
    20341 tgttactaaa ggatagcggt gctattcctg aagaattgag tagaataaga gcaatctctt
    20401 cacaaattac tattttatca tcatatgaaa actacgaaga atttaataaa ggactcacct
    20461 atatcaggca atttttaatg ttgctatccc tagtcttact catccttgtc attgcagtat
    20521 tgtcctttgt tttctttttg ctcaatcgtc ctcgacgctt tgaagtaggg attttaaaat
    20581 ctttgggata cagtactcaa aatattgttt ggcttttctt aaaagaatta attggttatg
    20641 gtaaaacaat ttcgatatta gcaagttgtt tactcgtcat tctttccatt ttagcaatgc
    20701 aagtgcttaa attggaaatt tcagatgttt ttaaattcta tctaacttcc gttttcacct
    20761 taattggatt atcagtctca gtactgataa taagtggctt actacctata tacacaactt
    20821 gtaggcaaac agttgtcgat actatccgaa agaatggatg aggtgatatc atgaaacata
    20881 agataatgaa aaaaataata gtggtagtgt ttgctatccc atggttaaca tttttaagtc
    20941 aagtacatgc agattatgta agtaagtcta gttctttaga cggttatagc ttggtaggct
    21001 tgaatgttct taatgtgact tttaatgctt ctggctattc tgatacttat agtggcagtg
    21061 tgtcaaatat gtatttcact gactgggctt ggtttcctaa tacgataagt aatcgttcca
    21121 cttggaaaag ttcgattcca tatggccaac gcgcaaatgg tacagtccat atagatgtag
    21181 gagtaaattc gccttgggga gcggttaatc tctggggcgg acaaaattac ttttctttag
    21241 atttttaaca gaaataatca aagttagata gaatgaataa gaatgctctt gatgatggta
    21301 tcaagagtat tttatgttat tcagattaat gcaaacattg ccctttcttg tcgcaggctc
    21361 cgtttcatga tacaatagaa ggagtgattt tagaaagcgt gagaaacatg atttactttg
    21421 ataattcggc gacgaccagg ccctatccag aagcccttga aacctatatg caggtggctt
    21481 caaaaatttt aggaaatcca tctagtctcc atcgtttggg agaccaggca acacgaattt
    21541 tagatgcttc ccgtcaacag attgcagatt taatcggtaa gaaaagtgat gaaatcttct
    21601 ttacatctgg tgggacagaa ggggataact ggatcatcaa gggagtagca tttgaaaaag
    21661 cccagtttgg caagcacatc atcgtatcag ccattgaaca tccagcagtt aaggaatcag
    21721 ccctctggtt gaaagctcaa ggttttgaag tggattttgc tccagttgat aacaaaggat
    21781 ttgtggatgt tgaggcgcta gaagatttga taagacctga tacgaccctc gtttccatca
    21841 tggcagttaa caatgaaatt ggctctgttc agcccattga ggctatttca aaactattgg
    21901 cagacaagcc aactatttcc ttccacgttg atgcggttca ggcgcttgcc aagattccga
    21961 ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt ctctggtcac aagttccacg
    22021 gaatccgtgg tgttggtttt atctatatca agtctggcaa gaagattacg cctcttttaa
    22081 caggtggtgg tcaggaacgt gattaccgtt cgacaactga aaatgtggca ggaattgcag
    22141 cgaccgctaa ggctctccgt ttatctatgg aaaagctaga tatctttagg agcaagactg
    22201 ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta tccggatata tttgtctttt
    22261 cagatgagga agacttcgcc cctcatattc tgacttttgg aatcaagggt gttcgtggtg
    22321 aggtcattgt tcacgccttt gaagactatg atattttcat ctcaacgacc tcggcttgtt
    22381 cgtccaaggc tgggaaacca gccggaaccc tgattgctat gggagtggac aaggataagg
    22441 ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga tatgagtcag gtcgagcagt
    22501 tcttgaccaa gctaaaatta atttacaatc aaactagaaa agtaagatag gagcattcat
    22561 gcagtattca gaaattatga ttcgctacgg tgagctgtca accaagggca aaaatcgtat
    22621 gcgtttcatc aataaacttc gcaataatat ttcagacgtt ttgtctatct atccccaagt
    22681 taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagcag attacacagc
    22741 agtagcagaa tcgctcaaac aagtatttgg aattcaaaac ttttcccctg tttataaggt
    22801 tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag attatgcagg acatctacaa
    22861 ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac cacacctttg aattggacag
    22921 tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa gccattccaa acgtacaagc
    22981 tcaaatgaaa agtcctgaca tcaatcttca ggtggagata cgtgaagaag cagcctatct
    23041 ttcttatgaa accgttcgag gggcaggtgg attaccagtg ggaacttctg gtaagggcat
    23101 gctcatgttg tcagggggaa tcgattcccc tgtagctggc tatctagcgc ttaaacgagg
    23161 ggtagatata gaggcagttc actttgccag cccaccttac acgagtcctg gtgctcttaa
    23221 aaaagcccaa gatttgaccc gtaaattaac caaatttggg ggaaatatcc agtttatcga
    23281 agttcctttt acagagattc aagaggaaat caaagccaaa gcgccagaag cctaccttat
    23341 gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt attcgtgagg tacgaaatgg
    23401 tttggttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc ttgaaagtat
    23461 gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta ccatggacaa
    23521 gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa tccaaccgtt
    23581 tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta aaattaagaa
    23641 tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag cagtggctgg
    23701 aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg acttgattga
    23761 taatctactc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa aaagttagtt
    23821 ttttttctaa aaacaggtaa aaaactaact tttttctatt ttcatgatat aatgatataa
    23881 aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc taaaaatgaa
    23941 agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc
    24001 taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc atgacgggca
    24061 aaatgttttt tatagcaaag agtctttcat tggatattca tggaagatta tcccagctat
    24121 caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg
    24181 gcgaatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag agcagcagtt
    24241 tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga
    24301 tgagacctat cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg
    24361 aggcaatatt acccagttta tcggtttgga ataccaagac caaattggtt gcttgggcgt
    24421 tttttcatct gcaaactggc tccaccaaga agcctttaac cgctatatcg agtgccagaa
    24481 actatcgcct gaccagcgca tcttcatcta tgtaggaaca gaagaagcag atgatacaga
    24541 caagaccttg atggatggca atatcaaaca agcctatatc gactcgtcgc tttgctatta
    24601 ccatgatttg atagcagggg gagtacatct ggataatctt gtgctaaaag ttcagtctgg
    24661 tgccatccat agtgaaatcc cttggtcaga aaatctacca gattgtctga gattttttgc
    24721 agaaaaatgg taagttaaga aaggaaaaaa cgaaatgcat attgaacatc ttagccactg
    24781 gagtggtcat cctaaccgtg aaatgtacct taaccgttat ggacatggtg ggattccagt
    24841 tgtggtcttt gcttcatcag gtagtagtca caacgaatac tatgattttg gcatgattga
    24901 tgcctgtgct tcctttatcg aggaaggccg tgtccagttc tttaccctat ctagtttgga
    24961 tagtgagagc tggttggcta cttggaaaaa tgctcatgac caagcggaaa tgcaccgtgc
    25021 ctacgaatgt tatgtgattg aggaggccat tcttttatca agcacaagac aggttggttt
    25081 gatggcatga tgacgacagg ttgctctatg ggagcctatc atgcactcaa tttcttcctc
    25141 cagcatccag atgtctttac caaagtgatt gctctcagtg gtgtttacga cgcacgtttc
    25201 tttgtcggtg attactacaa cgatgatgct atttaccaaa actcgccagt agattatatt
    25261 tggaaccaaa acgacggctg gtttattgac cgttaccgtc aggcagagat tgtgctgtgt
    25321 acggggcttg gagcctggga acaagatggt ttgccatcct tttacaagct caaagaagcc
    25381 tttgacaaga aacaaattcc agcctggttt gctgaatggg gacatgatgt agcccatgac
    25441 tgggaatggt ggcgtaaaca aatgccttat ttcctcggta atctctattt ataaaaggag
    25501 ttacctatga attaccttgt tatttctccc tactatccac aaaactttca acagtttacc
    25561 atcgaactag ctaataaagg catcacagtc ttgggaattg gtcaagagtc ttacgagcaa
    25621 ttggatgagc ccttgcgcaa tagcttgacc gagtattttc gtgttgataa tcttgagaac
    25681 atagatgaag tcaaacgtgc agttgctttt ctcttttata aacatggtcc aattgaccgc
    25741 atcgagtctc acaatgaata ctggcttgag ctagacgcaa cactcagaga acaattcaat
    25801 gtttttggtg ccaaaccaga ggatctcaaa aagacgaaat ataagtctga aatgaagaaa
    25861 cttttcaaaa aagcaggtgt tcctgtggta cctggagctg ttatcaagac ggaagcagat
    25921 gttgatcaag cagtgaaaga aatcggtctt ccaatgattg ccaaacctga taatggagtg
    25981 ggagcagccg caacctttaa acttgagaca gaagacgata tcaatcactt caagcaagaa
    26041 tgggaccatt caacccttta tttctttgaa aaatttgtca cttccagcga aatctgtacc
    26101 tttgacgggc tcgtggacaa ggatggaaag attgtcttct caacaacctt tgactacgcc
    26161 tatacaccgc ttgacctcat gatttataag atggacaatt cctactatgt gctcaaggat
    26221 atggttccca aactacgcaa gtatggggaa gcgattgtta aggaatttgg tatgaaagaa
    26281 cggtttttcc atattgagtt cttccgtgag ggggacgatt atattaccat tgagtacaat
    26341 aaccgccctg caggtggttt caccattgat gtttataact ttgctcattc cttggacctc
    26401 tatcgtggat atgcagccat tgtcgcagga gaagagttcc cagcgtcaga gtttgaacct
    26461 cagtattgtt tggctacatc acgtcgtgca aatgctcact atgtctattc tgaggagaac
    26521 ttacttgcca aatatagcca gcagttcaag gttaaaaaaa tcatgccaga ggcttttgcg
    26581 gaacttcaag gagattactt ttatatgctg acaactccga gtcgacaaga aatggatcag
    26641 atgattgctg atttcggaca acgtcaagaa taagaactat cggattaagg aaattcactc
    26701 ccttaatcct tttgttttgt ctggtaaaaa ataagagcat cctaacaagg tagctatcat
    26761 aaaacttgtt cgataactat ttgaagcagg attaggtggt tagaaattga attttaacat
    26821 ttcaattgag tcatagtatt gtgttttcgt atccttaaat cagctaaaag gatccatgac
    26881 gacacctata cgatatagtt ttcaggatac caaacaagtc tattaatact caatgaaaat
    26941 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
    27001 tagaactgac agagtcagta tcatatacct acggcaaggt gaagctgacg tggtttgaag
    27061 agattttcga agagtataaa atattcaggt gacgcataga tatagttaat tgaagctttg
    27121 tttgaaatct gataaaataa tgatattact aagttttaaa aactaaagaa aagggaagat
    27181 atgattacag gcgaattaaa aaataaaatc gatcagctgt gggaaattct ttggacagaa
    27241 ggaaacgcaa atcctttaac aaatattgaa cagttgactt atctcttatt tatgaaagat
    27301 ttggatagtg tcgagcttgg acgtgaaagt gatgctgaat ttctagggat tccttatgag
    27361 ggagtttttc caaaagataa acctgaatac cgttggtcaa cttttaaaaa tataggagat
    27421 gctcaggaag tttatcgttt aatgactcag gagatttttc cgtttattaa aaatctcaag
    27481 ggggatacag atgatacagc cttttcacga tatatgcgag aagctatttt tcaaataaat
    27541 aaacctgcta cgcttcaaaa ggcaatttct atcttagatg tttttccaac taggggatta
    27601 gatgtagatt ttgataatga caaacaaagt attactgata tcggagatat ctatgaatat
    27661 ctgttatcaa aattgtcgac cgcaggtaaa aatggacagt tccgtacacc tcgtcacatc
    27721 atcgatatga tggttgagtt gatgcaaccg actatcaaag atatcatctc agatcccgct
    27781 atgggttctg ctggcttctt agtatctgct agccgttact taaagcgtaa gaaagatgaa
    27841 tgggaaacca atacagataa tatcaatcat tttcataatc agatgtttca tggaaatgat
    27901 acggatacga ctatgttgag acttggggcg atgaacatga tgctacatgg agtagaaaat
    27961 ccacaaatca gttaccttga ctcgctgtct caagataatg aagaagccga taaatatact
    28021 ttggttttag caaatcctcc ttttaagggc tcacttgact acaattcaac ctctaatgac
    28081 cttcttgcaa ccgtaaaaac caaaaaaaca gaattactct ttctttctct tttcttgcga
    28141 actttaaaac caggtggacg agcagcagtt atcgtacctg atggtgtcct ttttggttcg
    28201 tctaaagctc ataaaggaat tcgtcaggaa attgtagaga atcataagct tgatgctgta
    28261 atctcaatgc ctagtggtgt tttcaagcct tatgctggag tttcaactgc cattctcatc
    28321 tttacaaaaa ctggtaatgg tgctactgac aaagtctggt tttacgatat gaaagcggat
    28381 ggtttaagtt tggatgataa gcgacaaccg attagcgaca atgatattcc agatattatc
    28441 gaacgctttc atcatcttga aaaagaagca gaacgtcaga gaacggatca atctttcttt
    28501 gttccagttg ctgagataaa ggaaaatgat tatgatttgt ctatcaataa atataaagag
    28561 attgagtatg aaaaagttga gtatgaacca acagaggtca tcttaaagaa aatcaatgat
    28621 ttagaaaaag aaattcaagc tggcttggct gaattggaaa aattactcaa gtagggaggt
    28681 ggctgtatga aaaaagtgaa gttgggggaa atcttatctc taaaaaaagg aaagaaagcc
    28741 actgtacttg ctgaacaaac aactctaagc caacgttata ttcaaataga tgatttaaga
    28801 aataataata atttaaaatt cactgaaagt ttaaatatga ctgaagcact cccagatgat
    28861 attctaatag catgggatgg tgctaatgca ggaacagttg gctatgggtt atcgggagct
    28921 gttggtagta caattacggt cttaaaaaag aatgagcgat acaaagaaaa aattatatca
    28981 gattacttgg gagtcttttt ggaaagtaaa tcgcagtatt tacgagatca ttcaacaggt
    29041 gcaactattc ctcatttaaa caagaatata ttacttgatt tacaattaga attgctaggt
    29101 atcgaagaac aagagaacat tatctgtatt cttaatacga ttaaaaggct tattactaaa
    29161 agaaaatttc agttagatga actaaacttg ctcgtcaaat cccgatttaa cgagatgttt
    29221 ggggatcctt taaataataa caagaaattt gcagtaaaaa cgggacaaca gtgttttaaa
    29281 ttttcaagtg gaaaatttct tgataaacat gatagagttt ttgaaggtta tcctgcctat
    29341 ggtggaaatg gcattgcttg gaaaagtcga aaatatttaa ttgataatcc tactatcatc
    29401 attggtcgtg taggtgcata ttgtggtaat gtaagaacta cccacggtaa ggtatggata
    29461 agtgacaatg ctatatatat aaaagaattt aagaattccg atttcaatct tgtattttta
    29521 ttagaattaa tgaaagtaat tgattttagt aaatttgctg atttctcagg tcaaccaaag
    29581 ataactcaaa aaccattaga aaatcagaaa tatatcctcc ccccactagc cctccaaaat
    29641 gagttcgcag actttgtagc cctggtcgac aaatcacaat tggcaatcca aaaatctctg
    29701 gaagaacttg aaactttgaa gaaatctctg atgcaggagt attttggctg atattctgcc
    29761 attgtaatta cggtaatgat ttgttataat acttcaaagg aggaaatcag atggtagtaa
    29821 aaacaagaaa acaaggaaat tcaatcacca ttacgattcc aagtgaattt aatattccaa
    29881 gtggtgttaa atacgaagcg aaattgttac aaagtggtga gattatcttt actcctgaag
    29941 aattggggca gcaggtttct catgtatctg atgatgcctt tgacttaaat ttagataaaa
    30001 tatttgacga atacgacgat gttttcaaag ctttggtgga aaaatgacaa tctatctgac
    30061 agaaaagcaa attgaaaaaa taaatgcttt agcaattcaa cggtattctc caaatgagaa
    30121 aattcaaaca gttagttctt ctgccttaaa tatgattgtg aacttaccag aacaatttgt
    30181 ctttgggaag tctctttatc caacaatttt tgataaagca acgatactat ttgtccaatt
    30241 gataaagaag catgtttttg ctaatgctaa taaaagaact gctttcttcg ttttggtcaa
    30301 atttttacaa ttaaacggct atcgtttttc tgtaacggta gaagaagcag taaaaatgtg
    30361 tgtaaccatc gcagtagaag ctttaactga tgaaaaaatg acaagctatt ccaaatgggt
    30421 ttctgaacat tctgttagag aaaaggtcaa aaagtaacct agtatgctgg atttgaatga
    30481 gcacaagaaa ataaatgaac agacaatatt agaattctgt aatgcagaaa ctgatattgt
    30541 ctctttttat tgatgaataa gaaagtgaga aattatggaa tcaaaagtta caattatcat
    30601 gcaagaaatg ttacctcttt taaataatga acaattacta gcgttgagag agagtttaga
    30661 acatcatcta gtagacggaa aaaagcagca gaagtattcg aataataacc tgttgcaact
    30721 atttattacc gccaagcagg tagagggctg tagctcaaaa acaattcgtt attaccagag
    30781 gacgattgaa aacttgttta atgctattaa agagtctgtg acacaactca caacagatga
    30841 tttaaggagt tatttagcaa attaccagtc tgaaaaggat tgtagtaagg caaatttaga
    30901 caatattagg cgtatattgt cttctttttt tgcttggctt gagcaagagg aatatatcat
    30961 taaaaatccc attcgacgga taaagaaaat taagactgag caaaatgtga aggaaactta
    31021 tactgatgaa catttggaaa ttatgcgtga taactgtgaa aatttgagag atttggcaat
    31081 aatagaccta ctagcatcga caggtatgcg tgtaggggag cttgtacagt tgaatcgttc
    31141 agatattgat tttgaaaaca gagagtgtgt tgtctttggt aaaggaaaga aggagagacc
    31201 agtatatttt gatgctcgga cgaaaattca tttaagaaat tatcttaacg acagaaaaga
    31261 tagtcaccct gctctttttg taacgctagt tggaaaagcc cagagacttg gaattgctgg
    31321 tgtagagatt cgcttaagaa agttaggaga caaactcggc atacaaaagg ttcacccaca
    31381 taagttcaga agaactttag cgactaaggc aattgataaa ggtatgccta tcgaacaagt
    31441 ccaaaaactg ctaggtcata gcaagattga cacaaccctg gcctatgcca tggtcaatca
    31501 aaataatgtc aagcattcac accaaaaatt catctcttaa aagcaaatcc cgatattccg
    31561 aggaggtggt tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatggcta
    31621 tgcttttaaa cctcaagatt ggtcatctga agggaaagag attatcagaa tacagaatct
    31681 gactaaaact tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt
    31741 tgaagctggt gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg
    31801 aagatccgca gtgttaaatc agcacatttt taaagtggtt tttgataaga tagatataga
    31861 taaatcgtat tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca
    31921 tggttccaca atgaaacatt taactaaaaa atattttgat aatattatag ttccatatac
    31981 aaatttggga gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt
    32041 aaggagacaa gaacaacttg aagagcttaa tctacttgta aaatcccgat ttaacgagat
    32101 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
    32161 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
    32221 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
    32281 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
    32341 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
    32401 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
    32461 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
    32521 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
    32581 tgagttcgca gactttgtag ccctggtcga caaatcacaa tttgcttgtg agatagctat
    32641 aaaagtgtgg agaaatagct tgaaatttag tataatatag ctaaactatt tgtttaaagt
    32701 gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg acgaatatga atctttttca
    32761 aaaccttgca ttgaagctga aaatatgatt gctacatcaa ctgtggctac tgcctttatg
    32821 gcccgtcgtg ctttagagca ggctgtccat tggatatata gtcacgattc atatttagaa
    32881 gctccctatc gtgctactct atcttcttta gtatgggatg atgattttag ggatatcgta
    32941 gattctgaac tccacaagca gatagttctg ttgattcggt ggggaaacca tgctgctcat
    33001 ggtggtgaaa ttaaggaacg agaagcgatt ttagctttac atcatttgta tcagtttgtt
    33061 aattttatcg attattgtta cagcaatgaa tttgtggagc gttattttga tgagaagtgc
    33121 ttaccacttt cagcaaacat caaataccga gaaactccac aatctatgat aaagttacaa
    33181 gacagtttac cagaactgcc tgattttcat gaacagatgg ctgctcagtc cgtagaagtt
    33241 caagagactt atactgaaaa acgtgagact gcagcgcaac ggcaagatgt gcctttccat
    33301 attgatcaat tatctgaggc agagacaaga aagctcttta ttgatatcga tctccgttta
    33361 gcaggatgga tatttgaaga aaactgtcgt gttgagatag ccgttgatgg tctcaagcac
    33421 ggttcaggaa ttggttactg tgactatgta ctttatggta aaaatgggaa aattttagcg
    33481 attgtagagg ctaaaaaagc ctctgtcaat ccagaagtag gggaagtaca ggtcaaagaa
    33541 tatgctgaag ctcttgagaa acatatcggc tatcagccaa tttgctttat tacaaatggc
    33601 ttgaagcact atatacttga tggtccgaac cgccgccaga ttgcaggctt ttactctcaa
    33661 gaagaattgc aattagtgat ggatagacgt catcttcaaa aaccacttga ggatatttct
    33721 agtaaaatta gggacgatat ttccgggcgt cactaccaaa aacacgcgat tgcaagcgtt
    33781 tgtgaagctt tctctaatca tcgtagacag gcacttttgg ttatggcaac tggggctggg
    33841 aaaactcgta cagcagtttc tctagttgat atcttatcac gtcataactg ggtaaaaaac
    33901 gttctcttct tagccgatag aacttccttg gttaagcaag cctatgattc gtttagaaaa
    33961 ttactcccag atctttccgt ttgtaacttc ttagaagata aagaaggagc tcaatcaagt
    34021 cgcatggtct tttcaactta tccgaccatg attggagcga ttagtggtca agaagaagta
    34081 aatcaacgcc ctttcactgt tgggcatttt gaccttatca taattgacga atctcaccgt
    34141 tctatttatc agaaatacaa gtccattttt gattattttg atgcaagaat tgtaggctta
    34201 acagctactc cgcgtcaaga tttagataaa aacacctatg gattctttaa tttggagaat
    34261 ggggttccaa catatgcata tgatttggaa gaggctgtta aagacggata tttagtagcc
    34321 tatcattcta tcgaaaccaa actgaaacta cctacggatg gtctacatta tgatgatttg
    34381 tccgaagaag aaaaggaaca ttttgatagc aaatttgaag acgatagctg tgaaaaagat
    34441 attgatggga gtgtatttaa ttcctttgtt ttcaataaaa gtacagtaga aattgtttta
    34501 aatgaactca tgacaagagg aattcagaca gcctcgggtg atgaaattgg taaaactatt
    34561 atttttgcta aaaatcatga tcatgcggaa tatatcagag gtatttttaa caaccgctat
    34621 cctgaaaaag ggagcgacta tgctcaggtg attgattata gtattaagca ttatcagacc
    34681 ttgattgatg attttaaaat taaggagaag tatcctcaaa ttgcgatttc tgtcgatatg
    34741 ttagatacag gtattgatgt accagaggtt gttaatttag tcttcttcaa gaaagtacgc
    34801 tctaaaacta agttttggca gatgattggt cgaggaaccc gtctatgtaa agatttattt
    34861 ggacctgagc aggataagga aaacttcttg gtatttgatt atggggacaa ttttgattat
    34921 tttcgtgcag atccaagaga tggagagggt cgtcacattg tttcgttgac tcagcgttta
    34981 tttaatatca aagtggactt gattcgagaa cttcagggac tccaatacca agaagatcag
    35041 tttgcgagag cataccgtca gcagcttgtc tcggaacttc aaggtcgtat agagagctta
    35101 aatgagttgg acttcagggt tcgtatggtt ttagatacag tttatagcta taggaaattg
    35161 gaaagttggc agaatctaac tactgttaca agtgaaacca ttcaaaaaaa tctctctccg
    35221 cttttatttg atgaagataa agaagatgag atggccagga gatttgattt gtggttgctt
    35281 catattcagt tggggcaact gacagctaaa tcttccactg ttcatatttc ccaagtgatg
    35341 aagacggcta gagctctttc tgctattggc aatatcccgc aggtttttga gcaggctgaa
    35401 attatcagga aagtacagga gcctgaattt tggaaagaag ttaacttgtc tgatttggaa
    35461 aaaattcgtc ttgctattcg agatttatta cagtttttgg ataaaacaga ccgtaaaccc
    35521 tactatgtta actttgaaga tcgtatactc tccactgttc acgagaccac agcatttttg
    35581 caggtcaacg atcttcggtc ttacaatgaa aaagttgagc attatttgaa aactcatctg
    35641 gatgaggagt ccatttctaa gctataccat aataaaaagt tgacatctga tgatatgctt
    35701 gcacttgaaa aattgctttg ggaaaaatta ggtagtaaag cagactacca aagtcattat
    35761 gaaaataagg caattccgag attggttcgt gagattattg gcttagatag agagtctgcc
    35821 aatcgtattt tttctaaatt tttgtcggat gagaatctta atgccaggca gatttcattt
    35881 gtaaaattga ttgtagacta cattgtagaa aatggttttt tagagacgaa agtgttaacg
    35941 caagagccgt ttaaatctta tggttctgtt caactactct tccaacacca actaccagta
    36001 cttcgtaata ttgttcaaat cattgaactt atcaataatc gagctggaga agcggcttaa
    36061 attctaaagt gattgccatg ctgagactca tttaaaatta aaaagagtag aaatttatgc
    36121 tatatatgag aagttttatt aggaagaatg tcatcgtttt cctagaatac agtatcagtt
    36181 gttaagtggt tgataaattt caaagtagat acttgtacca cgatgtttgt tgatcgagtt
    36241 attaacaaaa gagctacttt gattttaaag aaatagaaaa caaaaagccg agcaagaatt
    36301 caattgcagg agaaaatgaa ataatactca ataaaaatca aagagcaaac taggaaacta
    36361 gctgcaggct gctcaaaaca ctgttttgag gttgtagata agactgacga agtcagctca
    36421 aaacatggtt ttgaggttgt agatgaaact gacgaagtca gtaaccatac ctacggcaag
    36481 gcgacgttga cgcggattga agagattttc gaagagtata aatcttccta ggataaagca
    36541 aaacgcatag tatcaagggt tttcaacact tgatactatg cgttttctga tgttaaagac
    36601 tttctaccag tttttttaag cataattgtt agttgtagtc atttattatt cttcaaagaa
    36661 aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat ctgcatcttc
    36721 acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag ggaagctcaa
    36781 agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta gtaggacttg
    36841 gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga gacgtttttc
    36901 ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt cgcggacttt
    36961 tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt gaatgtcgtt
    37021 cttagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg tgataagagc
    37081 gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc ttttagcaag
    37141 gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta ttgtcacgga
    37201 tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct tcttttagct
    37261 tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca gtaatatcct
    37321 ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc acgactcgtt
    37381 gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag cgaccgttgt
    37441 caatggttct agcacttaaa atagctggat aaggttgtag gtatttcttt tgcccaaatt
    37501 ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga agattgagct
    37561 gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta atctgattag
    37621 ctttcccttg atagagctct gtattgaagg tttggtatgt cttaccatag cgctcaaaat
    37681 ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag aaggtttcac
    37741 agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct gtattgtcct
    37801 gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc ttggtcaata
    37861 aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa acatgagcac
    37921 cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac atctggtaaa
    37981 catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc tctgccttta
    38041 ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag tccccagttt
    38101 ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca ttgccacgga
    38161 tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag tcaaagtcct
    38221 cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag ttgtaccatg
    38281 atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta gtcgcaagac
    38341 cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg tttgaccaat
    38401 cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacgg ccgttaagcc
    38461 aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc atgaaacctg
    38521 tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc ggaaggaagt
    38581 agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc tctgctataa
    38641 gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc tcaatcttgt
    38701 gaggaagctt aacctcaagc tcgccctcca tcttgtagag agccttgtca ctagccttgt
    38761 cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt ccatcaaaac
    38821 gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca gtatcgacac
    38881 gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta gccaaactct
    38941 tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta acaagttggt
    39001 cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga ttttcaatca
    39061 agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta tcttcgaagt
    39121 caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata tctgctgtca
    39181 gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct gctaggatag
    39241 aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag gtttcaagtg
    39301 agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt tcagataaga
    39361 cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa cctccatata
    39421 gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt taacttcaaa
    39481 aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa cagagtaaca
    39541 ataagaataa atagataggg tataaaagtt ctaggagatt tatattatat gctttctatt
    39601 tttatataca atatagtata aatataaaaa tgatgacaaa aatacaaatg aatagaaaat
    39661 aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga aaatggtata
    39721 atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat acaaaaacag
    39781 tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca gctaaagaat
    39841 acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct ttcgactttc
    39901 tagagattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg acagtgtttg
    39961 tagatgatca ggaagtgaat ttgcgctttt tagctctatc tagtgtgggc tatcagcagt
    40021 tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc ctgtcccagt
    40081 acctggagga tatcgcggtc attgtgcctt attttgatag agttgagtcg ttagaactag
    40141 gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt catcatccta
    40201 tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt cttcaagttt
    40261 taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg agacaagatg
    40321 tctttatatc agcaagttct ttagagaaac tattccaaga gcgttttccg caagctttgg
    40381 acaatttaga aaagcttatt tcaggcattt cttacgactt ggatattagt ctgaaactgc
    40441 ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct gaactggggt
    40501 ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa gaattgtctg
    40561 ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg ttgcgttttg
    40621 gacgatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc agtttggttt
    40681 cttatgcctt agacatcacg gggattgacc cagtaaagaa aaatctgatt tttgaacgct
    40741 ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca gatatttatc
    40801 gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg gcacaaatcg
    40861 ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa cgctttggtg
    40921 tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac aatcttaagt
    40981 cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta gaataccaaa
    41041 aagcttttga gattgcttgc aagatagagg gctatccaag gcaaacctct gtccatgcgg
    41101 ctggtgttgt aattagtgac caagatttaa ccaactacat tcctctaaag tatggtgatg
    41161 aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt ttgaagatgg
    41221 actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg cttgctgaaa
    41281 cagaaggtat tcaccttaaa attgaagaaa tagatttgga agacaaagaa acgttagatt
    41341 tatttgcctc tggaaataca aaaggtatct ttcaatttga gcaacctggt gccattcgct
    41401 tgctcaaacg tgttcaacca gtctgttttg aagatgtcgt agcaactact tctctaaatc
    41461 gaccaggtgc aagtgactac atcaataatt ttgtggcaag gaagcatggg caggaagaag
    41521 tgactgttct agattcagct ctggaggata ttttggctcc aacttatggc attatgctct
    41581 atcaggagca ggttatgcag gttgctcagc gatttgctgg atttagtctt gggaaggccg
    41641 atattttgcg tcgagctatg ggtaaaaagg atgcctctgc tatgcatgag atgagggctt
    41701 cctttattca aggctccata gaagcaggcc atactgcgga aaaagcagag caggtttttg
    41761 atgttatgga gaagtttgca ggttatggat ttaatagatc tcatgcctac gcctactcag
    41821 ccttggcctt ccagttggct tatttcaaaa cgcattatcc agccattttt tatcaggtca
    41881 tgttaaatta ttccaacagt gattacttaa tagatgcact tgaagcaggt tttgaagtag
    41941 cctctctatc catcaatact attccctatc acgataaaat tgccaacaag tctatctata
    42001 taggtttgaa atcgattaag gggctcagca aggacttggc gctttggatt attgaacata
    42061 gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat ctgaaacttc
    42121 ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa aatcgtcaaa
    42181 aagtatttaa taacttagct aatctatttg aatttgtgaa agagttggga agtttgtttg
    42241 gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa aaattttata
    42301 tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct attgcaagta
    42361 aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat gctattattt
    42421 tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat atggccttct
    42481 tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac ttatatcgtc
    42541 aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa atacaatcac
    42601 gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct gaacgctttt
    42661 ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgcatttta gaacaattta
    42721 aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc gtttctcccc
    42781 atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc gttatgaaaa
    42841 cgatttatcg ctaaaaatac ggaaaataga agaattttaa aatcaaatgt gatataatca
    42901 agaagaatgt taaaagaaaa aggagcataa accaatatga aacgtattgc tgttttgact
    42961 agtggcggag acgcacctgg tatgaacgct gccatccgtg cagttgttcg tcaagcaatt
    43021 tcagaaggaa tggaagtgtt tggtatctat gacggatatg ctggtatggt tgccggtgaa
    43081 attcatcccc tagatgcagc ttcagtaggg ggcatcattt ctcgtggtgg tacttttctt
    43141 cactcagctc gttatccaga gttcgctcaa cttgaagggc aacttaaagg gattgagcaa
    43201 ttgaaaaaac acggaattga aggtgtagtt gttatcggtg gtgacggatc ttaccacggc
    43261 gctatgcgtt tgactgaaca tggcttccca gctattggtc ttccaggtac aatcgataac
    43321 gatatcgttg gtactgactt tacaatcggt tttgacacag cggttactac tgccatggac
    43381 gctatcgata agattcgtga tacatcatca agtcaccgtc gtacttttgt aatcgaagtt
    43441 atgggacgta acgctggtga tatcgctctt tgggctggta ttgcaactgg tgctgatgaa
    43501 atcatcatcc ctgaagcagg cttcaagatg gaagatatcg tagcaagcat caaagctggt
    43561 tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg aaggtgtgat gtcagcggct
    43621 gaatttggtc aaaaacttaa agaagctgga gatacaagcg accttcgtgt aacagaactt
    43681 ggacatattc aacgtggtgg ttctccaact gcgcgtgacc gtgttttggc gtcacgtatg
    43741 ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg gtgttgcggt tggtattcgt
    43801 aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag aagaaggggc attgtttagc
    43861 cttactgcag aaggtaagat tgtggttaac aacccgcaca aagccgatat tgagctatct
    43921 agcttgaata agagcttgtc ataatttaca atttagttaa taagaccaaa aaggtcatat
    43981 atataaagga gtcacaaaaa tcatgaacaa acgtgtaaag atcgttgcaa ctttgggtcc
    44041 tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggat ggatactggg gtgaaaaact
    44101 tgatgttgaa gcttcagcta aaaacattgc taaattgatt gaagctggtg ctaacacatt
    44161 ccgattcaac ttctcacacg gcgaccacca agaacaaggt gagcgtatgg caactgttaa
    44221 acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt cttgatacaa aaggacctga
    44281 aatccgtaca gaattgttcg aaggtgaagc taaagaatat tcatataaaa ctggtgaaaa
    44341 aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt gaagtgattg cgttgaacgt
    44401 tgctggtgct cttgatatct atgatgatgt tgaagttggt cgtcaagttt tggttgacga
    44461 tggtaaactt ggtcttcgtg tggttgctaa agatgatgca actcgtgaat ttgaagttga
    44521 agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg aacatcccta acactaaaat
    44581 tcctttccca gctcttgctg aacgcgataa cgacgatatc cgtttcggtc ttgaacaagg
    44641 tatcaacttc atcgcaattt cattcgtacg tactgcaaaa gatgtgaacg aagttcgtgc
    44701 aatctgtgaa gaaactggaa acggacatgt tcaattgttc gctaaaatcg aaaaccaaca
    44761 aggtatcgat aacttagacg aaattatcga agcagctgat ggtattatga ttgctcgtgg
    44821 tgatatgggt atcgaagtac cgttcgaaat ggttccagtt tatcaaaaaa tgattatcaa
    44881 gaaagtcaat gctgcaggta aagttgttat cactgcaaca aacatgcttg aaacaatgac
    44941 tgaaaaacca cgtgcaactc gttcagaagt atcagacgta ttcaacgctg ttatcgacgg
    45001 aactgacgct acaatgctgt caggcgagtc tgcaaacggt aaatacccac tcgagtcagt
    45061 aactacaatg gctacaatcg acaagaacgc tcaagctctt cttaatgaat acggacgtct
    45121 tgattcagat tcatttgagc gtaactctaa gacagaagta atggcttctg ctgttaaaga
    45181 tgctactagc tcaatggata tcaaattggt tgtaactctt actaagacag gtcatactgc
    45241 acgtttgatt tctaaatacc gtccaaatgc tgacatctta gcattgacat ttgacgaatt
    45301 gacagaacgt ggcttgatgt tgaactgggg tgttatccca atgttgacag atgctccatc
    45361 ttcaactgac gatatgttcg aaatcgctga acgtaaagcg gtagaagcag gtctcgttga
    45421 gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta ggagaagctg ttcgcacaaa
    45481 cacaatgcgt atccgcacag tacgttaaga aaaatataaa aacctatcat atctagcttt
    45541 ctagcctgta tgatgggctc tttttttgtc cagggggcaa aactttcata atggatt
//
LOCUS       DBEJJE010000011        45566 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEJJE010000011 DBEJJE010000000
VERSION     DBEJJE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.11"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            80..460
                     /locus_tag="ACL3F5_000615"
     CDS             80..460
                     /locus_tag="ACL3F5_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514462.1"
                     /translation="MKLKRLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            994..1686
                     /locus_tag="ACL3F5_000616"
     CDS             994..1686
                     /locus_tag="ACL3F5_000616"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0514463.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFIGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1739..4150
                     /locus_tag="ACL3F5_000617"
     CDS             1739..4150
                     /locus_tag="ACL3F5_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0514464.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTQFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4400..5101
                     /locus_tag="ACL3F5_000618"
     CDS             4400..5101
                     /locus_tag="ACL3F5_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514465.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5103..7811
                     /locus_tag="ACL3F5_000619"
     CDS             5103..7811
                     /locus_tag="ACL3F5_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0514466.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7907..8398)
                     /gene="tpx"
                     /locus_tag="ACL3F5_000620"
     CDS             complement(7907..8398)
                     /gene="tpx"
                     /locus_tag="ACL3F5_000620"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0514467.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8521..9450)
                     /gene="psaA"
                     /locus_tag="ACL3F5_000621"
     CDS             complement(8521..9450)
                     /gene="psaA"
                     /locus_tag="ACL3F5_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0514468.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9482..10330)
                     /locus_tag="ACL3F5_000622"
     CDS             complement(9482..10330)
                     /locus_tag="ACL3F5_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0514469.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10327..11049)
                     /locus_tag="ACL3F5_000623"
     CDS             complement(10327..11049)
                     /locus_tag="ACL3F5_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0514470.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11340..13232
                     /gene="pepO"
                     /locus_tag="ACL3F5_000624"
     CDS             11340..13232
                     /gene="pepO"
                     /locus_tag="ACL3F5_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0514471.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13355..13984)
                     /locus_tag="ACL3F5_000625"
     CDS             complement(13355..13984)
                     /locus_tag="ACL3F5_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0514472.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(14324..14566)
                     /locus_tag="ACL3F5_000626"
     CDS             complement(14324..14566)
                     /locus_tag="ACL3F5_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514473.1"
                     /translation="MTRFEEILEECKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            14977..17199
                     /locus_tag="ACL3F5_000627"
     CDS             14977..17199
                     /locus_tag="ACL3F5_000627"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR0514474.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17229..17672
                     /gene="dtd"
                     /locus_tag="ACL3F5_000628"
     CDS             17229..17672
                     /gene="dtd"
                     /locus_tag="ACL3F5_000628"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0514475.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELINNGPVTIILDTKKR"
     gene            complement(18144..18557)
                     /locus_tag="ACL3F5_000629"
     CDS             complement(18144..18557)
                     /locus_tag="ACL3F5_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514476.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18688..19395)
                     /locus_tag="ACL3F5_000630"
     CDS             complement(18688..19395)
                     /locus_tag="ACL3F5_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGR0514477.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGP
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFSIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQMSQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANTLNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(19512..20162)
                     /locus_tag="ACL3F5_000631"
     CDS             complement(19512..20162)
                     /locus_tag="ACL3F5_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0514478.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20274..21116
                     /locus_tag="ACL3F5_000632"
     CDS             20274..21116
                     /locus_tag="ACL3F5_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0514479.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21192..21629
                     /locus_tag="ACL3F5_000633"
     CDS             21192..21629
                     /locus_tag="ACL3F5_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0514480.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21698..22000
                     /locus_tag="ACL3F5_000634"
     CDS             21698..22000
                     /locus_tag="ACL3F5_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514481.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(22091..23164)
                     /locus_tag="ACL3F5_000635"
     CDS             complement(22091..23164)
                     /locus_tag="ACL3F5_000635"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0514482.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            23320..23997
                     /locus_tag="ACL3F5_000636"
     CDS             23320..23997
                     /locus_tag="ACL3F5_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0514483.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIGDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23990..24964
                     /locus_tag="ACL3F5_000637"
     CDS             23990..24964
                     /locus_tag="ACL3F5_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR0514484.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(25013..26956)
                     /gene="thrS"
                     /locus_tag="ACL3F5_000638"
     CDS             complement(25013..26956)
                     /gene="thrS"
                     /locus_tag="ACL3F5_000638"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0514485.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(27014..27190)
                     /locus_tag="ACL3F5_000639"
     CDS             complement(27014..27190)
                     /locus_tag="ACL3F5_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0514486.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(27197..27337)
                     /locus_tag="ACL3F5_000640"
     CDS             complement(27197..27337)
                     /locus_tag="ACL3F5_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0514487.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(27594..27968)
                     /locus_tag="ACL3F5_000641"
                     /pseudo
     CDS             complement(27594..27968)
                     /locus_tag="ACL3F5_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28207..28836
                     /locus_tag="ACL3F5_000642"
     CDS             28207..28836
                     /locus_tag="ACL3F5_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0514488.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28977..29246
                     /gene="rpsO"
                     /locus_tag="ACL3F5_000643"
     CDS             28977..29246
                     /gene="rpsO"
                     /locus_tag="ACL3F5_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0514489.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            30061..30675
                     /locus_tag="ACL3F5_000644"
     CDS             30061..30675
                     /locus_tag="ACL3F5_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0514490.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30967..31716)
                     /locus_tag="ACL3F5_000645"
     CDS             complement(30967..31716)
                     /locus_tag="ACL3F5_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0514491.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31849..34185
                     /locus_tag="ACL3F5_000646"
     CDS             31849..34185
                     /locus_tag="ACL3F5_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0514492.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLARVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAHAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34287..34964
                     /locus_tag="ACL3F5_000647"
     CDS             34287..34964
                     /locus_tag="ACL3F5_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0514493.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEEIDQVSVITIAGMGGCLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQNHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            34951..35748
                     /locus_tag="ACL3F5_000648"
     CDS             34951..35748
                     /locus_tag="ACL3F5_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0514494.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            35765..36868
                     /locus_tag="ACL3F5_000649"
     CDS             35765..36868
                     /locus_tag="ACL3F5_000649"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0514495.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            37124..38143
                     /gene="galE"
                     /locus_tag="ACL3F5_000650"
     CDS             37124..38143
                     /gene="galE"
                     /locus_tag="ACL3F5_000650"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0514496.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            38145..39110
                     /locus_tag="ACL3F5_000651"
     CDS             38145..39110
                     /locus_tag="ACL3F5_000651"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0514497.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(39161..39367)
                     /locus_tag="ACL3F5_000652"
     CDS             complement(39161..39367)
                     /locus_tag="ACL3F5_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0514498.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            39419..39895
                     /locus_tag="ACL3F5_000653"
     CDS             39419..39895
                     /locus_tag="ACL3F5_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0514499.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            39904..40575
                     /gene="cmk"
                     /locus_tag="ACL3F5_000654"
     CDS             39904..40575
                     /gene="cmk"
                     /locus_tag="ACL3F5_000654"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0514500.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLVVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            40706..41044
                     /locus_tag="ACL3F5_000655"
     CDS             40706..41044
                     /locus_tag="ACL3F5_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0514501.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            41047..41676
                     /locus_tag="ACL3F5_000656"
     CDS             41047..41676
                     /locus_tag="ACL3F5_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0514502.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            41916..43067
                     /locus_tag="ACL3F5_000657"
     CDS             41916..43067
                     /locus_tag="ACL3F5_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0514503.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            43379..44128
                     /gene="truA"
                     /locus_tag="ACL3F5_000658"
     CDS             43379..44128
                     /gene="truA"
                     /locus_tag="ACL3F5_000658"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0514504.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            44118..44891
                     /locus_tag="ACL3F5_000659"
     CDS             44118..44891
                     /locus_tag="ACL3F5_000659"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0514505.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGIPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            44869..45330
                     /locus_tag="ACL3F5_000660"
     CDS             44869..45330
                     /locus_tag="ACL3F5_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0514506.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        13206 a         8562 c        10424 g        13374 t
ORIGIN      
        1 tataatatca gaacatactt tttttaaaag caaatatgat acaattttat ttgaaaaaaa
       61 taaaaaagga gattttatta taaaattaaa aagacttgct ttaattagtg gtatcgtcgg
      121 tcttgtggga ggaattttac ttcttattgg tccttttgtc ttgttgggaa cagcggtaaa
      181 cacagctgct acaactctta atggaggagc tactgcaggg gctttttcag gtgtagcctt
      241 actcttgaat gccttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta
      301 taaaggagat aagcgtgtag gtgcagctcc gtctgtacta atgattgttt ctggtggagt
      361 tagtctcatt ccattcttag gatgggttgg ggggattctt gctattatcg gaggatctct
      421 attccttgca acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa
      481 gaacaaaaag tttatcggta taggagtagc tctattatct ctttctcttc tagttgcatg
      541 tggaacataa agttcaaaga atacttcaac aagtaatgat gagaagacag tagcaacatc
      601 caatagttca aaagaaacaa tcactttcga tacaccggtt gtaacagacg atgcgattga
      661 atcaatacgc acttatgcag attatataga tctttataaa aatatttttg atgattattt
      721 tactaaagct gaggaaggtt tcaaaggcac agctatggaa aataatgact cgtttactaa
      781 actaaaagag tcaactcaaa aattattcga tgcgcagaaa aaaaggttaa ataatgaaga
      841 tagaatagaa acaaccaaaa acaatgtgat tgccaaacat tgtcaaacag tcctttcctt
      901 tttggttttg actagctttt ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg
      961 aaacctcgga aaatttaaag gagaatccat ctaatggtaa aattggtttt tgctcgccac
     1021 ggtgagtctg aatggaacaa agctaacctt ttcactggtt gggctgatgt tgatttgtct
     1081 gaaaaaggta cacaacaagc gattgacgct ggtaaattga tcaaagaagc tggtatcaaa
     1141 tttgaccaag cttacacttc agtattgaaa cgtgctatca aaacaactaa cttggctctt
     1201 gaagcttctg accaattgtg ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac
     1261 tatggtggtt tgactggtaa aaataaagct gaagctgctg aacaatttgg tgatgagcaa
     1321 gttcacatct ggcgtcgttc atacgatgta ttgcctccaa atatggaccg tgatgatgag
     1381 cactcagctc acacagaccg tcgttatgct tcacttgacg actcagtaat cccagatgct
     1441 gaaaacttga aagtgacttt ggaacgtgct cttccattct gggaagataa aatcgctcca
     1501 gctcttaaag atggtaaaaa cgtattcata ggagctcacg gtaactcaat ccgtgccctt
     1561 gtaaaacaca tcaaaggttt gtcagatgac gagatcatgg acgtggaaat ccctaacttc
     1621 ccaccattgg tattcgaatt cgacgaaaaa ttgaacgtcg tttctgaata ctaccttgga
     1681 aaataaaaaa ttgtaagcct aggattgatt tctaggcttt ttatgttagt atggaagtat
     1741 gataaggaat aaaaaacaag attatgtact ggcctacaag caaccagctt caaccactta
     1801 catgggttgg gaagaagaag ctttaccgat aggcaatggt tctttaggag caaaagtatt
     1861 tggccttata ggggctgaac ggattcaatt taatgaaaaa agtctctggt ctggaggtcc
     1921 acttcctgat agttcagatt atcagggtgg aaatcttcag gatcagtatg gttttttagc
     1981 tgagattcgg caggctttgg agaagagaga ttacaatctg gctaaggaac tggctgagca
     2041 gcacctaatt gggccaaaaa cgagtcaata tgggacctat ctgtcttttg gggatattca
     2101 cattgagttc agccagcaag gtacgacttt gtctcaggtg acggactatc agagacagct
     2161 gaatattagt aaggcacttg cgacgacttc ttatgtctat aagggaacgc aatttgaacg
     2221 tgaagctttt gcgagttttc cagatgatct cttggttcaa tgttttacta aggaagggtt
     2281 ggaaactcta gattttacta tagaactatc cttgacctgt gatttggctt ctgatggaaa
     2341 gtatgagcag gaaaaatctg attacaagga gtgtaagttg gatattactg attctcatat
     2401 cttgatgaag ggaagagtta aggataatga tctgcggttt gctagttatc tagcttggga
     2461 aacggatgga gatattagag tttggtcaga tagggttcag atatcaggag ccagttatgc
     2521 caatctcttc ttggccgcta agacggattt tgcccaaaat cctgctagca attatcgcaa
     2581 gaaactagat ttagagcaac aggtgataga cttggtggac acagctaaag aaaagggcta
     2641 tacccaattg aaatcaaggc atatcgagga ctaccaagcc ttattccagc gtgttcaatt
     2701 ggatttggaa gctgatgttg acgcatccac tacagatgat ttgttaaaaa attataagcc
     2761 acaagaaggg caggctttgg aggagctgtt cttccagtat ggacggtatt tattgattag
     2821 ttcgtccaga gactgcccag atgctctacc agctaaccta cagggagtct ggaatgcggt
     2881 cgacaatcct ccttggaatt cggactatca cttaaatgtc aatctgcaga tgaattattg
     2941 gccagcctat gttaccaatc ttctagagac ggtctttcca gtcatcaact atgtagatga
     3001 tttgcgtgtc tatggtcgtc tagcggctgt aaagtatgca ggaatcgtct ctcagaaagg
     3061 tgaggagaat ggttggttgg ttcatactca agcgactccc tttggttgga cggcacctgg
     3121 ttgggattac tattggggtt ggtcaccagc tgccaatgcg tggatgatgc aaaccgttta
     3181 tgaagcctat tcattttata gggaccaaga ctatctcagg gagaaaattt atcccatgtt
     3241 gagggaaacg gttcgttttt ggaatgcctt tttacataag gatcagcagg cgcagcgttg
     3301 ggtgtcttct ccgtcttatt ccccagaaca tgggccgatt tcgattggca atacttatga
     3361 ccaatctctg atttggcagt tatttcatga ttttattcag gctgctcagg aattgggact
     3421 ggatgaggac ttgttgactg aggttaagga gaagtctgat ttactaaatc ctttgcaaat
     3481 cactcaatct ggtcgaatca gggagtggta tgaggaggaa gagcagtatt ttcaaaatga
     3541 gaaagtggag gcccagcatc ggcacgcttc ccatctagta ggactctatc ctggcaatct
     3601 ctttagctac aagggacaag agtatattga agcggcacgt gctagcctca atgatcgtgg
     3661 agatggcggc acaggctggt ccaaggctaa taagatcaat ctctgggcgc gtttgggaga
     3721 tggcaatcga gcccataaat tattggcaga gcagttaaaa acatccacct tgccaaatct
     3781 ttggtgtagc catcctcctt ttcagataga tggtaatttt ggtgctacta gtggcatggc
     3841 agaaatgtta ctccagtctc atgcagctta tctggtacct ctagctgccc tacctgatgc
     3901 ttggtcaaca ggttctgttt caggcttaat ggcacgtgga cattttgaag tgagcatgag
     3961 ctgggaagat aaaaaactct tacagttgac cattttatca aggagtggag gagatttgcg
     4021 agtttcttat ccagatattg agaagagtgt gattaaaatg aatcaagaaa aaataaaagc
     4081 gaaatgcatg gggaaagatt gtatttcggt ggcaacagca gaaggtgatc ttgttcaatt
     4141 ttatttttaa gaagatgtta taaggcagta atttgaaact gccttttaat aaggatttaa
     4201 gaatataagc agttttcaac tagttgaaaa agcgttataa tgataatagg aagtaatact
     4261 caatgaaaat caaagagcac aaactaggaa gctagccgca ggttgctcaa aacagtgttt
     4321 tgaggttgca gatggaagct gacgtggttt gaagagagat tttcgaggag tataatttgt
     4381 ttgatagagg gtgggtctga tggcttatat tgagatgaaa cactgttaca agcgttatca
     4441 ggttggggac acggagattg tggccaatcg tgatgtgaat tttgagattg aaaaggggga
     4501 gctggttatt atccttggtg cttcaggtgc aggcaagtca acagttctta accttcttgg
     4561 gggaatggat accaatgatg aaggggaaat ctggattgat ggtgttaata ttgcggatta
     4621 tagttcccac cagcgcacca attaccgtag aaatgatgtg gggtttgttt ttcagtttta
     4681 taatctagtt tctaatctga cagctaagga aaatgtggaa ctggcttctg aaattgtgac
     4741 agatgccttg aatcctgatc aggtcttgac agatgtaggt ctggctcatc gtctcaataa
     4801 ctttccagcc cagctttctg gaggggagca acagcgagtc tccattgcac gcgcggtagc
     4861 caaaaatcct aaaattctcc tttgtgatga accgactgga gccttggatt atcagacggg
     4921 caagcaggtt ttgaaaattc tccaagacat gtctcgtcaa aagggagcga cggtgatcat
     4981 cgtgactcat aatggagctt tggcgcccat tgctgatcgc gtgattcata tgcacgatgc
     5041 cagtgtcaag gatgtggtgc tcaaccagca tcctcaggat attgacagtt tggagtacta
     5101 gcatgatcaa gcgaaaaact tattggaagg acttaattca gtccttcaca gactccaagg
     5161 ggcgtttttt atccatcttg atcctgatga tgttgggatc tctagcctta gtaggcctca
     5221 aagtaaccag tcccaacatg gaggcgacag ctaatgctta tttaacaact gctcaaacct
     5281 tggatttggc agtcatgtct aactatggct tggatcaagc agaccaagaa gaactaaaac
     5341 agacggaggg cgcagaggtc gagtttggct atttgacaga tgtgactatg gataatgggc
     5401 aggatgccat tcggctgtac tccaaaccag agcgaatttc aacctttcag ctaagaaagg
     5461 gacgacttcc tcagtcagac agggaaatcg ctttggccac tcatttgcaa ggccaataca
     5521 gcgtgggaca ggagattagt tttaaagaaa aagaagaggg tcattcctct ttaaaagacc
     5581 atacttatac cattactggt tttgtggatt cggctgaaat cctctcccag cgagatatgg
     5641 gctacgcagg aagtggaagt gggactctga cagcctatgg ggtgatttta cctagtcaat
     5701 ttgatcagaa agtctacaat atagctcgtt tgaaatatca agatttagca ggtttaaatg
     5761 ccttttcatc agcttatgaa gaaaaatcca agcaacatca ggaagacctt gaacaaactt
     5821 tatcagataa tggcaaggta cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag
     5881 acaaggggca agagaccctt gacaaggctc agactaattt gcaggaaggc aagcgtcgtt
     5941 tagcagctgc tcaagctcgt atacaggctc aagaaagtca actagccttg tttcctcaag
     6001 ctcagagaga gcaggctagt gctcaactta cccaagccaa gcaggaactg ggcaaggaag
     6061 aggacaaact aaagcaagct gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac
     6121 atcagcaagt cttggatgat ttggcggagc caaggtatca ggtttataat cgtcagacca
     6181 tgccaggtgg tcagggctat cttatgtata gcaatgcttc atccagtatt cgagcagtgg
     6241 gcaatatctt tcctgtggta ctttatgccg tagcagccat ggtgaccttt acgaccatga
     6301 ctcgctttgt agacgaagag cgaactcatg cagggatttt taaggccttg ggttatcgta
     6361 gtaaggatat tatcgccaag tttctccttt atggactagt agctgggact gtcggaacgg
     6421 ctctaggtag tatacttggt cattatttgc tagccagtgt aatttcaagt gtcattacaa
     6481 aaggcatggt ggtgggagaa acccagattc agttctattg gacctatagc ttactagctc
     6541 ttgtcttgag ctggttggcg agtgtgttac cagcctatct ggtggcttgg agggaacttc
     6601 atgacgaagc agcccagctt ctacttccta aacctcctgt caaaggagct aaaatcttat
     6661 tggagcgtat cggttttatc tggcgtcgtc tcagttttac tcataaggta acagcccgca
     6721 acatctttcg ttataagcag agaatgttga tgacaatctt tggtgtggca ggttctgtag
     6781 ctctgctctt tgcaggtttg ggaatccaat cttctgtagc aggagttccg tctaaacagt
     6841 ttcaacaaat ccaacagtat cagatgcttg tctctgaaaa tcctagtgcg accaatcagg
     6901 acaaggtaga gctagcagaa gtattgaaag ggcaggagat actagcctac cagaaaatct
     6961 attctaaaac gctagacaag gatttcaaag gcaaggctgg tcttcaaaac attactctta
     7021 tgatgataga gaaggaagat ttgactccct ttatccatct tcaacatcat cagcaggagc
     7081 tgacattaaa agatggcatc gttattacag ctaaactcgc ccagctggca ggtgtcaagg
     7141 ttgggcagac tttagaaatt gaaggtaagg aactaaaggt cgctgctatt actgagaact
     7201 acgttggtca ctttatttat atgagtcagg ctagctatga gcaactttac ggacagctac
     7261 cccaagccaa cacttatctg gtctcattaa gggataccag tgcaactagt atcgaaagtc
     7321 aggcgggctt gcttatgaat caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca
     7381 ttcgactctt cgactctatc gctagctcac tcaatcagac catgaccatc ttggtcatcg
     7441 tatcggttct attagctatt gtcatccttt acaatctgac caatatcaac gtagctgaga
     7501 gaatccgtga actctccact atcaaggttc tcggttttca taataatgaa gtcaccctct
     7561 acatttaccg tgagacgatt gtgctgtccc ttgtgggaat cgtacttggt ctgatagctg
     7621 gtttctattt acaccaattt ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc
     7681 cgcaggtagg ctgggaagtc tatgtaatcc cagtggcagc agtaagcatc attttgacct
     7741 tgcttggttt cttcgtcaat tattatctga gaaaggttga tatgttagaa gctctgaaat
     7801 ctgtagagta aggtaattat ttttagctga ttgaacttct atttactaat attcaaaaat
     7861 cctccgtttc aaagagcagg gaactctttg tgacagagga ttttttctat agggctttag
     7921 cagctgcaat tgcggcttcg aagtttggct cagaattgat attatccacg tattcaacgt
     7981 agcgaatcgt attgtcagta tcgaggacaa agactgcgcg tgctaatagg tgccattcgt
     8041 tgatcaagag ggcataatcg cgcccgaaag aatggtcaaa gtagtctgaa agcataatgg
     8101 cattgtcaag gccttcagca ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa
     8161 cagtcaatac gaccgtgttg tccagtccag ccaattcttc attaaaacga cgtgtttgag
     8221 ttgagcagat acctgtatcg atagaaggaa cgacactcaa gacttttttc ttgccatcaa
     8281 aatcagccag agatttttta gaaagatctg ttgtagtaag agaaaaatca agcgccttgt
     8341 cgccgacttg tagttgttta cctgtaaagc tcacaggatt tccgagaaaa gttaccatag
     8401 gatactccaa tcttttttct tccattgtat ctaaaacagt cagaattttc caatgatttg
     8461 accggaaatg tgtgcataga aaaaacgcca gctcacatga gaatgacgtt tttcagaggc
     8521 ttattttgcc aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct
     8581 gtcgccttct ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt agattgggat
     8641 gtttgtgtct tgagaaacag ttttcattgg acggtcatcc acacttgatt ctacaaagag
     8701 tgatggaact tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc
     8761 ttcttcttca gtattgattt cccagatgta ggcacttggg acaccatagg ctttagagaa
     8821 gtatttgaat gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa
     8881 tttatcctta ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt
     8941 ttcatagaat tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc
     9001 aaaaataata ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt
     9061 ttgaccttca aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc
     9121 agttttcttg gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt
     9181 gataccgtta tagaaaatca aatcagcctc agaagttttc ttaacgtctt caggaagtgg
     9241 ttcgtattcg tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc
     9301 agcaatattt ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg
     9361 accagaagtt gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa
     9421 gagaacgagt aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc
     9481 cttattttaa caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga
     9541 agctaatgag aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa
     9601 aactatagcc aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga
     9661 aaatcatact tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca
     9721 tggctacaat caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga
     9781 gtaccatgag aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt
     9841 catcaaagga agttatcaag agttgcttga agaaaatcca gattaacaag aggatggctg
     9901 cccccacacc catagtaata aacatatccg tatcttggac ggccaggata ttaccaaaaa
     9961 ggatatggaa aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta
    10021 agaaagaaga aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga
    10081 tgtaggtaat gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa
    10141 ggcccaagat gaaggagagg gctacacctg gtaagacagc atgtgaaatg gcatctccca
    10201 tgagtgacat cccgcgtaga ataatgaaac atcccacggc tccagctaca atcccgacga
    10261 caatagctgt tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt
    10321 ctgcaatcat aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt
    10381 ggtttcggta aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa
    10441 gacttgatcg aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt
    10501 cccagctttt ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagagtcaat
    10561 cccagcaaag ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat
    10621 caagacccgc tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc
    10681 taggccgacg atttcaaggg cctcttgcac tttcttccaa tgtttagcct ttaaacttcg
    10741 aaagagagga atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa
    10801 gttgtagtcg atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac
    10861 ttccttgtca tcgagaaatg cctgaccttg atgtgggata attcccagca taccttttaa
    10921 tagtgttgat ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag
    10981 cactagtgaa atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttcgat
    11041 acgtatcata aacttgtatt cctcctgtct cttaatatac attaaaaaaa aaattaagtc
    11101 aagttaattt ttgaaaaaat taaaataata actgaaaaat agattctaaa gataactttc
    11161 aggataaatt tctaaattat aaaacgcata gtatcaagtg taaaaaactt ggaattatgc
    11221 gttttatcat ggaaagtttt tttataatag ctaaaaaata atagttaaat ggttattaat
    11281 tgcattccct agtgattttt gttaagataa atgcaaatac aaatgaaagc gagaacaaga
    11341 tgacacgtta tcaagatgat ttttatgatg ctatcaatgg agaatggcaa cagacagctg
    11401 aaatcccagc agataagtct caaactggag gttttgttga tttagaccag gaaattgaag
    11461 acctgatgct ggcgacaaca gacaagtggt tagcaggtga agaggtgcct gaggatgcta
    11521 tcttggaaaa ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag agagaagctg
    11581 acggtatcac acctgtctta ccactcctta aagaattcca agaattggag acttttgcgg
    11641 attttacagc taaactagca gagtttgagc ttgcaggaaa accaaacttc cttccttttg
    11701 gtgtatcgcc agactttatg gatgctagaa tcaatgttct atgggctagc gctccaagca
    11761 caatcttgcc agatacgacc tactatgcag aagaacatcc tcagcgcgaa gagctcttga
    11821 ctctttggaa agaaagcagc gcaaatctcc tcaaggctta tgatttctct gatgaagaaa
    11881 ttgaagactt gctagaaaaa agacttgaat tggaccgccg agttgcgaca gtggtgctct
    11941 ctaatgaaga aagttcagaa tatgctaaac tctatcatcc atattcttac gaagatttca
    12001 agaaattcgc gcctgcccta cctttggatg acttcttcaa agcagttatt gggcaattac
    12061 cagacaaggt tattgtagac gaggaacgtt tctggcaagc agcagagcaa ttctacagtg
    12121 aggaagcctg gtctctcctt aaagcaacct tgattttgag tgttgtcaat ctttcaacca
    12181 gctatttaac agaggatatt cgtgttttgt ctggtgccta cagccgtgcc ctttctggag
    12241 ttccagaggc aaaagataag gtcaaagcag cttatcatct agcacaggaa cctttcaagc
    12301 aagccctggg gctttggtac gcccgtgaga agttctctcc agaagccaag gcggatgtgg
    12361 agaaaaaagt ggcaaccatg attgatgtct ataaggagcg tctgcttaag aatgactggc
    12421 tcactccaga aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa ccttatattg
    12481 gctatccaga agaattgcct gcacgttaca aggataaggt agtgaatgaa actgccagtc
    12541 tttttgagaa tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga
    12601 accagcctgt agactataag gaatggggca tgcctgctca tatggtcaat gcctactaca
    12661 atcctcagaa gaacctgatt gtctttccag cggccatttt acaggcgcct ttctatgact
    12721 tgcatcagtc atcttctgct aactacggtg gtattggggc agtgattgcc catgaaattt
    12781 cccacgcctt tgatactaac ggggcttcct ttgacgaaaa tggtagcctc aaggattggt
    12841 ggacagagag cgactatgct gccttcaagg agaaaacaca aaaagtcatt gaccaatttg
    12901 atggacagga ttcttatgga gcaaccatta acggtaaatt gactgtatca gaaaacgtgg
    12961 ctgacttggg aggaatcgca gcagcgcttg aagcagctaa gagagaagca gacttctcag
    13021 cagaagagtt cttctacaac ttcggtcgca tctggcgcat gaaaggtcgt ccagaattta
    13081 tgaaactttt ggctagcgtc gatgtgcacg caccagccaa actccgtgtc aatgtgcaag
    13141 taccaaactt cgacgatttc tttacaacct atgatgtcaa agaaggagac ggaatgtggc
    13201 gttcaccaga ggagcgcgtg attatttggt aatacaaaaa atctagtcat cagaaaaaag
    13261 gcatccaatc acgtgtgaaa accttgatag gatgcctttt gtaatagaaa gatttgctgg
    13321 atagtttact taaatttcga ttgtcatcat cttgctagaa aaagggattg aaggcctttt
    13381 cgtgagcgat agtagtagct ggaccatgtc ctggatagac atcgtagttt ggtagggtga
    13441 agagttgggt ctggatacta tgaaggagtt gctccatgct accagtcgga aggtcggtcc
    13501 gtccgatagt ttcgcggaat agagcatctc ccgtcaagac taggtgagca tcaggaaaga
    13561 ctagggaaac accaccgata gagtgccctg gggtcggtag aaccttaaaa cgaaattcct
    13621 ctagttggta ttcttcgtga aagacaaagg tgtgttctgc aggttttgtg accacatctg
    13681 ccatatcatc gtggcgaggg agaccggaga gattatcgac aggagtgtag agccagctgg
    13741 cttcgctctc tgcgatatag acaggaggat tgccaaacgt ctcgcgaacc aagtccagac
    13801 tcatgatatg gtcataatgg gcgtgggtca agagaatagc acagatcggt ttgttgatct
    13861 tctcgattgt ctgacgaatg gcttcccaat gactaccagg atcgacgacg atgaggtgct
    13921 tttcgccttc tagataatag gtattttcat aggcaacagg attcacggtt ttatggattt
    13981 tcatactagc tccaatctca aagaatgtac taatactctt cgaaaatctc ttcaaaccgc
    14041 gtcaacttta tctgcaacct caaagcagtg ctttgaacag cctgcggcta gctttctagt
    14101 ttgctctttg attttcattg agtataaatt aagtatagca cagttaggga gaataggtaa
    14161 ggatttaaaa tgaacttaaa aaccagcatg actagatgaa gacaggctgg ttatcaattt
    14221 atcaatattg gaaaggtgtc aattgccctt cataggttgc ataaactccg tcattagctt
    14281 gtttgataga cgtgatgttt agagtgctac cgtagttggc ttctcatttg tcgctatatt
    14341 cactataagt tatcctactg ggcaggttct ggtcgttagc atagtattga acgagttttt
    14401 tatagctttg ctggctgaat aggaacaggc agcaaactcc taacattagg agagcaaaga
    14461 tagaaatagc agttttttca taggtattct ccttataaac taaaggatag aagaaagtat
    14521 cttgaggatt tttacactct tcaagaatct cttcaaaccg cgtcaacgtc gccttgccgt
    14581 atatatgtga ctgactttgt cagtcttatc tacaacctca aagcagtgct ttgagcaacc
    14641 tgcggctagt ttcctagttt gctctttgat tttcattgag tattaattcc aaaatccagt
    14701 caaggtacca gtgtatgtga tacgagttcc accgtttatc tttcgtatct tcaatggaat
    14761 tggggaaatc agaaagtctt tgggttacaa tatggtttcc gttcttctat ctctccttct
    14821 atcacctaag tttaaaatct aacttcgtag tatattatgg gccaataatt cagaattatc
    14881 aagcaatttt gaattatttt tttcttattc tgttccaatc tagttttcat attcttaaaa
    14941 aagtgataaa atggtaggaa gaattggaga gtagagatgc cgaaagaagt gaatttaaca
    15001 ggcgaagaag ttgtcgcttt aaccaaagaa tatttaacgg aagaggatgt tcattttgtc
    15061 cataaggcct tggtctatgc tgttgaatgc cacagtggtc aatatcgcaa atcaggcgag
    15121 ccttatatca ttcaccctat ccaagtggca ggtattttag ctaagctaaa gctggatgct
    15181 gtaacagtag cttgtggatt cttgcatgat gtggtggaag atacagatgc gaccttggac
    15241 gatttggaaa gagagtttgg tcctgatgtg cggatgattg ttgacggagt taccaagctt
    15301 ggcaaggtcg agtacaaatc gatcgaggag caattagcgg aaaatcatcg caagatgctc
    15361 atggccatgt ctgaggacat ccgcgttatt ttggtcaaac tgtctgaccg cttgcacaat
    15421 atgcggaccc tgaaacatct tcgaaaagac aagcaggagc gtatttccaa agaaaccatg
    15481 gaaatctatg ccccgcttgc ccatcgtttg gggatttcca gtgtcaaatg ggaattagaa
    15541 gacttgtctt tccgttatct caatccaacg gagttttaca agattaccca tatgatgaag
    15601 gaaaagcgca gggagcgtga ggccttggtg gatgaggtag tcacaaaatt agaggagtat
    15661 acgacagaac gtcacttgaa agggaagatt tatggtcgtc ccaagcatat ttactcaatt
    15721 ttccgcaaaa tgcaggacaa gagaaaacgg tttgaggaaa tctatgatct gattgctatt
    15781 cgttgtattt tagataccca aagtgatgtt tatgccatgc ttggttacgt gcatgaattt
    15841 tggaaaccga tgccaggtcg cttcaaagac tatattgcca accgcaaggc caatggttat
    15901 cagtctatcc atacgactgt ttatggacca aaagggccga ttgaattcca gattcgaacc
    15961 aaggaaatgc acgaggtggc tgagtatggg gttgcggctc actgggctta taagaaaggt
    16021 ataaaggggc aagttaacag caaggaatca gctattggaa tgaactggat caaggagatg
    16081 atggagctcc aagatcaggc tgatgatgct aaggaatttg tggactctgt taaggaaaac
    16141 tatctggctg aggagattta cgtttttacc ccagatggag ctgtccgttc ccttcccaaa
    16201 gattcaggac cgattgattt tgcctacgaa atccatacca aggtcggtga aaaagcaact
    16261 ggtgccaagg tcaatggccg catggttcca ctgacaacca agttaaagac aggggatcag
    16321 gttgaaatta tcgccaaccc gaactccttt ggacctagcc gtgactggct caatatggtc
    16381 aagactagca aggcgcgcaa taagattcgc cagttcttta aaaaccaaga taaggaattg
    16441 tctgtcaaca agggtcgtga gatgctgatg gctcagttcc aagaaaatgg ctatgtggca
    16501 aataaattta tggacaagcg ccacatggat caagttctgc aaaagaccag ttacaagaca
    16561 gaagactccc tctttgcggc cattggtttt ggggaaatcg gtgcgattac cgtctttaac
    16621 cgtctgactg aaaaggaacg ccgtgaggaa gagcgtgcca aggccaaggc tgaggcagag
    16681 gagcttgtca aaggtggcga ggtcaaggtt gaaaataaag aaaccctcaa ggtcaagcat
    16741 gaggggggag tggttattga aggtgcttct ggtctcctag tgcggattgc taagtgttgt
    16801 aaccccgtgc ctggtgacga tattgttggc tacattacca agggtcgtgg tgtggctatt
    16861 caccgtgtgg actgtatgaa cctgcgtgcc caagaaaact acgagcaacg tctccttgat
    16921 gtggaatggg aagaccagta ctctagctca aataaggagt atatggccca tatcgatatc
    16981 tacggtctca accgtacagg actgttgaac gatgtactgc aagttctttc aaatacaacc
    17041 aagaatattt caacggtcaa tgcccaacca accaaggata tgaagtttgc taatatccat
    17101 gtgtccttcg gtattgccaa cctctctaca ctgactacgg ttgtcgataa aattaagagt
    17161 gtgccagaag tttactctgt caaacggacc aacggctagt tgtcctagct cttactagaa
    17221 aggctattat gaaaatcatt atccaacggg ttaaaaaagc ccaagtgagt atagaaggcc
    17281 agattcaggg aaaaatcaat cagggacttt tattgctggt tggtgttgga ccagaggacc
    17341 aagaggaaga tttggactat gctgtgagaa aactggtcaa tatgcggatt ttttcagacg
    17401 cagaaggcaa gatgaaccta tctgtcaaag atattgaagg agaaatcctc tctatttctc
    17461 agtttaccct ctttgcggat actaagaaag gcaatcgtcc agcctttaca ggggcagcta
    17521 aacctgatat ggcatcagac ttctatgatg ctttcaatca aaaattagcg caagaagtgc
    17581 ccgttcagac aggtatcttt ggagcagata tgcaggttga gctgattaat aacggacctg
    17641 ttaccattat cctagatact aaaaagagat aagaaagacc aagcccagtc ggcttggtct
    17701 ttctcataga tcataaaata ctccaaaaag aaatcggttc ttgatatgct tgggggaagt
    17761 ctcttttcag gctttggcag atgcgatagg aagggatgag atgtcctagg atgaggagag
    17821 ttccctgaag gaaaagcgga atattactta aagacaccaa ggagagaatc atcaggctat
    17881 cccataggag aatttgtaaa gcaaaacgcc agaatctcgg tctaatctgg gaatagagtt
    17941 aactaaagtg gtcacaaagt tggtttgaaa gataggtcaa tagcacagga tgaaagaaaa
    18001 tgagccaacc gctataaatc aaaatccagt cccaagtaag cccccctttt aaatgtcaaa
    18061 aatgccagca tgattccatc aatgacaagg agttgaatgg ttttgatgaa gatgattttt
    18121 ttcatgctaa aacctccttt tccttagaga cactcccata aagagatgtg tttgtcgtaa
    18181 aagtctggat agttttctct taggtagtca gctgtcatat aataaaaagt agaatggcaa
    18241 gcagtgatga ttggcataag agatgaaaaa cgctgagaac taatgaaggc taagagaaca
    18301 aaaaatagaa aatcaatggt gagaacccct aaatagtaga agcgaatctt tttattgatt
    18361 tgaggataaa tctcagcgaa ttgatgtttg agtcggacga tcaagagaaa tagcaggagt
    18421 ccttgagcaa ggaagaaaat taaaccagag agcaagagcc actcaaaaga tgtctcgagt
    18481 ctaatgataa aaaatgcaaa tagtagcaaa tcaataactg caattgctat aaaatggatt
    18541 ctatagagtt ttttcatgac aagacctccc tcttttatct aacttcattc tactccaaaa
    18601 gaatgggagt tacaactaaa atgataaaaa tagcagaagg gagattctct taagttggct
    18661 agtattcttt atttgagttt ccttctatta tctaacttct tcatcattcc agacaaataa
    18721 agctccgatt gcattgagga tataaaagat gtatttaccg atattggcga agtttccttg
    18781 aataccagct tttgtcagct gaacgaaatt gtaaatcaac caaaagcccc actgagttgt
    18841 tagttttaat gcattcaaag tattggcaat gagggatagt gcaaaggcaa tagttgttac
    18901 gtaggcaagg agattcatct tgccctcata tccgatatag ttggtcacaa aggcaaagag
    18961 gaaggcgatg atggaaatga tgatgaccgc caattttacc tgtttttggc tcatttggtt
    19021 gggtctgcct tcttgcgaag ctttccattt ctttatagca aaggtataaa tgaggaaggt
    19081 gacgggatag gtaatgatgg ccgccttatt tccaaggata taatcaatag caccggacaa
    19141 aatggtatta acaatactaa agtaatttcc ccatttgctt aatttccccg tgaaacgagt
    19201 ggacaacatg gaaatcccaa cgttggttac ggaaatcaat ccaaagggta caagagctgt
    19261 ccatggtccc cagtctacaa atttatcgag gcgtgagttg aggtaaccag atgcaatcgc
    19321 aatcccaacg accaaagcaa ccccgaagag gtcaaaccat ttagatgtag caaaaatttt
    19381 tagtgatttt ttcataggtt aaactacctt tctttttttc aaatattctc gcaccaaatg
    19441 aaagtaaaat aaaatgatag aaataaaacc ctgaaaataa aactttcagg gttggtaggg
    19501 gacttgagaa attagttgat tttctcgaca tagagttgtt ttgcaatgtc catattcact
    19561 tgtaaatcct cgtcgttact gaggatagtg aaggtattgc tgaagccatc aaactgcttg
    19621 acttggagct ggtcaccgat gtgaagtgag tgcttgtcca gataatggag aatgtcaaaa
    19681 ttatcgtgca cccgagtcag gcggtaggcg ccagcttcct tgatatcagc tagtgggagg
    19741 ttattgattt caacgaggag ttctcccttg gcaggaatag ttcctccgtg ggggcaggtt
    19801 ttagggaaac ctagcagttt atctagtctt tccacgaaca ggtcagagac agtgtgttcc
    19861 aagacctcag cttcctcgtg aatctggtca cttgtatagt ctaaatgatg aactagaaaa
    19921 acttcaatca agcggtgctt acgatagagc tcagagacca gtttgagacc gaggtcagtc
    19981 agtagatagc cacattcctt gtcctttagg atgagatttt cacttttcat tcgtttgatc
    20041 atttcagtta cggcaggggg agagacttgc atgcgagccg caatttcctt gttggtaatc
    20101 ttatgcaggt ctatgccaat ttcataaata cattttagat agtcttcttt gtttggggtc
    20161 attcgtttcc tcttgtctaa tatctttatc tagtatatca aaaaaagcta gatttctcta
    20221 gctgtgactt tttatgttat acttattgca agagaaaaaa cgaggagatg gatatgacaa
    20281 aaatagctct tctttcagat attcatggaa ataccaccgc cttggaggct gttttggcag
    20341 atgctcagca gctaggagtg gatgaatact ggcttttggg agatattctc atgccaggga
    20401 caggacgtag aaggattttg gacttgttgg atcaactacc gattacggct agagttttgg
    20461 gaaactggga agacagtctt tggcatggtg tccgtaagga attggacagt actcgcccca
    20521 gtcaacgcta tctcttgcgc cagtgccagt atgttttaga ggaaatttcc ctagaagaaa
    20581 ttgaagtgct ccacaatcaa cctcttcaaa ttcatcgtca gtttggggat ttgacggtgg
    20641 gaattagcca tcatctgcct gataagaact gggggcgaga gttgattcat actggcaaac
    20701 aagaggagtt tgaccgcttg gtgactcatc ctccctgtga tattgctgtt tatggacata
    20761 ttcaccagca gttgcttcgt tacgggactg gtgggcaatt gattgtcaat ccgggttcga
    20821 ttggccaacc tttctttttg gacgctcagc tacggaagga cttgcgggcc cagtatatga
    20881 ttttggagtt tgatgacaaa ggcctggtag atatggactt ccgacgggta gactacgatg
    20941 tggcagcgga attgcagctg gctaaagacc tgagacttcc ctattttgag gtttactatg
    21001 aaagtctggt caatgggatc caccatactc atcatcagga atttttgaga gaattggctc
    21061 agaaagaggg ctgcgaccgg gagttagacg actggttgaa aagtggtaac gattgacatt
    21121 acaactaaaa agggtataat aatagaaaaa gaagagtaga ggcagggtag cctcgtaaaa
    21181 aggagaagag gatgcaaatt ccaagtagat ttaccattgc gactcatatg ctgataatca
    21241 ttgccctcga ggggaaggaa agcaaggtga ccagtgattt tctggctgct agtgtcgggg
    21301 tcaatcctgt cattatcaga aagatcttgt cccagttgaa gaaggcagag ctgatttcag
    21361 tagcgcgtgg aacgggcgga acagagattg tcaaggacct taaggatatt agtcttttag
    21421 atgtttatca ggcggtcgaa tgtcttggta agacaggtca actcttcagt ttccatgaca
    21481 atccgaatcc aaattgccct gtaggagctc atattcatga tgttttggat caaaaattgg
    21541 agagaattca gttgactatg gaggcagaac ttggtcagac cagtctagaa aaagtcgtgg
    21601 ccgatgcaga gagtcagatg aaggattaag agggataaat gccctctttt tttctttgga
    21661 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta tagaaattgt
    21721 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    21781 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    21841 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    21901 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaaacgag agggacgttc
    21961 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    22021 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    22081 ttcaagagta ttatctattt ttccatgcat ggtaacgagt atcaatcaat aactgggtaa
    22141 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    22201 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcatcaa
    22261 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    22321 cccattcttt aaaggttgtg tctacttgcc ggctatcact gttggtctta tccagttgaa
    22381 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    22441 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    22501 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    22561 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    22621 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcca
    22681 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    22741 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    22801 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    22861 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    22921 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    22981 gcatggtggg ctctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    23041 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    23101 ttaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    23161 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    23221 atagcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctagc
    23281 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattaata
    23341 gaagatgatc aggtcattcg tcaacagatt gggaaaatgc tctctgaatg gggatttgaa
    23401 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    23461 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    23521 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    23581 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    23641 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    23701 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    23761 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    23821 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    23881 ggtgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    23941 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    24001 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    24061 tttggcattt cttgtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    24121 ctactttttc ttcttgtgtt gctttgtaac catattattt ttcacttggg acatattggt
    24181 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    24241 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    24301 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    24361 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    24421 gcagcagctg gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    24481 cctgcgttta gaaagtttcc atgatgattt gctcttaaag caggttcaaa ttgaggactt
    24541 ggtcaaggaa ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa
    24601 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    24661 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    24721 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    24781 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    24841 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    24901 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    24961 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    25021 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    25081 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    25141 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacgg atcttgaact
    25201 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    25261 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    25321 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    25381 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    25441 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    25501 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    25561 ctgcttcacc ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca
    25621 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    25681 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    25741 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    25801 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    25861 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    25921 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    25981 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    26041 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    26101 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggtaacc
    26161 agaatggcaa accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa
    26221 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    26281 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    26341 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacggcct gttgatggaa
    26401 catgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    26461 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    26521 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    26581 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    26641 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    26701 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    26761 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    26821 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    26881 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    26941 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    27001 ttttatcagc agactacttc cgagtcctaa cgttcaattg cttttcttta tcagagagga
    27061 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    27121 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    27181 gctttgtcat caccagtcat tggaaatttc caatatcatt agataaagcc aagaggtctt
    27241 cttctaccgt ccacttgaaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    27301 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    27361 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    27421 gagggacacc tctgatcggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    27481 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    27541 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    27601 ttttgtgaaa gttttttgtt tttcattttt tgtagaatat gcttgatgct aataccagaa
    27661 tccatgccga ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    27721 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    27781 cggaaacagt agctatagag taacgatata atcaagatta ccagaggtgt aaagaagaga
    27841 agattgttta tatagagttc cttgagtgta agggggtcag aaacaactag taagaacaac
    27901 tcataaagtg gccaataaaa gaataatatg accagatagt aggggagatg ggaatagaat
    27961 ctacgcatga taatcacctc gttttaaaaa aacagacaac ttagatctct tgctatgatt
    28021 attatagcat gtttaaaaca agaaagtaaa tttgttgaca aagaagattt ttcttttcac
    28081 tagaatcata gttagttttc ttggtagaaa tattttgata ataattaagc aagactattg
    28141 acattgatta ttaagagtgt cacaattatt gtaactaaaa taattacaac aagagaggta
    28201 taaaaaatga aactagcagt tattgcagca aatggacaag cggggaaagc aattgttgaa
    28261 gaagcagtca aacgaggaca tgaagtaacg gctattgttc gttctgaaaa caaaagtcaa
    28321 gctgagtcta ttattaaaaa agatttattt gagttgacaa aagatgatct tactggattt
    28381 gatgctgtta tttcagcgtt tggtgcttat acaccagata cgctaccgct ccacagcaaa
    28441 tcaatcgaac tatttaatca gcttcttgct ggaacacaga cacgttttct agttgtaggg
    28501 ggatcaggaa gcttttatat agatgaaaca aaaacgacac gacttttaga tacgtctgat
    28561 tttcctgaag aatttaagcc actagcaaaa gctcaagcgg atgaattgga tcttcttcgt
    28621 acaaaaaata atctcaactg gacttttgtc agtcctgctg tagattttat tcccgatggt
    28681 gaaaaaacag gaaactacat tctagcagga gaaattttta ctactaatga aaaaggaata
    28741 agccagatta gttatgcaga ttatgctatt ggattggtag atgaacttga aaaaggtcat
    28801 catataaaag aacgtatctc tttacttgaa aaataataac tatgagagta ttaatgtttg
    28861 acagaaaatt taaatcttgg taaaataggg attgtcgtaa agacaaataa cttcttcttg
    28921 gttacaggca tgccaacctg tcactcggat gaagccaaat aaaaaggaga aacatcatgg
    28981 caatctcaaa agagaaaaaa aatgaaatca tcgcacaata tgcacgtcac gaaggtgata
    29041 caggttcagt agaggttcaa gttgctgtcc ttacttggga aatcaaccac cttaacgaac
    29101 acatcaaaca acacaaaaaa gaccacgcta cttaccgtgg attgatgaaa aaaatcggtc
    29161 gccgtcgtaa cttgcttgca tacttgcgta aaaacgacgt taaccgttac cgtgagttga
    29221 tcaactctct aggacttcgt cgctaattca agatacaaat gctgtcaaaa gtacaaagca
    29281 aaaataggaa aattgacgaa gaaacttcag tttctaggag attttatctt ttttgccaag
    29341 tgcttaggcc gtgttcaatt gagcatatct tgataatgaa gctactctaa attgggtagc
    29401 tttgttgcgt tgtcacctta cctcgctata ctcaagtata gtcttcggtt acggttccta
    29461 gcactgtaag gtaaaataaa ccagcttttc tcccttcggg gagatttttt tgtttcactg
    29521 aaagtttcgt acgatcttcg cctcgtcgcc tagtctataa acgatttatc tagcaagaat
    29581 catgatgcta agggcgtcaa aaatccgtat gaaaataggg aaatgacaca gtgttcgatg
    29641 agcacaagga gtttcatctt tttcactagg attttagccc gggctcaaat cagctctctg
    29701 acttcagagg gcttttttat tgaggtttta tcggtaacaa ttttggagac tacaaaaacc
    29761 tcaaatggta tcagctaatt acaccataaa ggtgcgcagt tactcggctt ttcaagccga
    29821 gtagctgtat gcaagccccc tagaagagcc cactctttac aaagtaaagt atagtatgtt
    29881 atactttaca tggaagtagt cactgaattc cagttagaaa ttactttgta actacgtttt
    29941 gaggaggagt aaaatgcttt cctacgttcg atattaccca ctagcgatag ctaaattaat
    30001 gtgtctgtgc tctcctaaaa tctgctgatt tattactgac taatacagga ggtttttttt
    30061 atgggacaga caatcatatc tgctattggt gtttatattt ccaccagtat tgattattta
    30121 attattttaa ttattttatt tgcacagcta tcacagaata aacagaaatg gcatatttat
    30181 gcggggcaat atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc
    30241 gttaatttcg tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta
    30301 gggattcgct ttgcaattgt tggagaagat gcggaagaag aagaggaaga aattattgaa
    30361 agattagaac aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg
    30421 tctggcggag ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag
    30481 accctcgtgg ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg
    30541 gtgttatcct ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg
    30601 cccttagtat tcattctact tggactatac atcatgtatg aaaatggcac gatagagact
    30661 tttctgatcg tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc
    30721 tctgattttc agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt
    30781 gtagagtggc ttttgatttg attaggagat tcttataaat atagtaaaat gaaataagaa
    30841 taggacaaat cgatcaggac agtcaaatcg atttctaaaa atgttttaga agtagaggtg
    30901 tactattcta gttccaatct actatataaa tgaaaacctt agctgtttgg ccaaggttca
    30961 tttcttctat gcaagttctt ctcttttctt atctgggttc cagatgaagc ttgcgataaa
    31021 gctaaagatg atggttagga tagcgaggat aatagcaagg atgagggcag ggatgcggat
    31081 aaaccaccag agtggatttg gttttttatc attgtgccat tgtttcgttt cttcgtccag
    31141 acgttggaat tctgtttgaa tacgattggc gactgtttca atgccttcat cattcatttt
    31201 cttgatatct gagatatcga ttggatttcc aaagttcata tcgacacgtt cacggctaat
    31261 caagcccttc aaagtcatgg gaccggtgta ggtaaccggc atgatacgga ccttggccat
    31321 tttggcaatc agtgctgcgc cccccttgac atcgtttgag tggcggctac cacttggaaa
    31381 catgatgaga gagcggtcac tttttttgag aacgttgata ggatatttga tggctgaggc
    31441 gctgggattt tcacggtcga tgggaaaggc gccacacata cgaatccacc aaccaaagat
    31501 acggttggta aagagttctt tttttgccat aaagatgaac tgttttggct tggtcgcaaa
    31561 ggccatataa acaggatccc accaggtacg gtgaggcgca actaaaatat aattttcatc
    31621 ttgattagga attttatcag tattatgata gtgagcattg ccattgatgg accataagag
    31681 caacacaact aatccacgca aataagtata aaacatgcga tctccttcga ttgttttctt
    31741 gttattatta taccttatca aaggagggct ggcaaacttt tcccttgact agatgcatat
    31801 ttgggatgag attagaattc tgttaaaaaa aatgatataa tagaatttat ggataaaaat
    31861 aagattatgg gattaaccca aagagaagtc aaggaaagac aggctgaggg tttggtcaat
    31921 gactttaccg catcagccag taccagcact tggcaaatcg ttaaacgaaa tgtctttacc
    31981 ctttttaacg ctttgaactt tgccattgct ttggcccttg cctttgtgca ggcttggagc
    32041 aatctggtct tctttgctgt tatctgcttt aacgcttttt ctgggattgt gaccgagcta
    32101 cgagccaaac acatggtgga caagctcaat ctcatgacca aggaaaaggt caaaaccatc
    32161 cgtgatggtc aggaagttgc tcttaatcct gaagaattag tgctaggaga tgtcattcgt
    32221 ttgtctgcag gagagcagat tcctagtgat gccttggttt tggaaggctt tgcggaagtc
    32281 aatgaagcca tgttaacggg agaaagtgat ttggtgcaaa aggaagttga cggcttactt
    32341 ttgtcaggaa gtttcctagc cagtgggtca gttttagctc gtgtccatca tgtaggtgca
    32401 gacaactatg ccgccaaact tatgctggaa gccaagaccg ttaaacccat caactcccgt
    32461 atcatgaaat cgctggacaa gctagcaggt tttactggga agattatcat tccctttggt
    32521 ctggctctct tgctggaagc cttgctttta aaaggcctgc ctctcaagtc atctgttgta
    32581 aattcgtcga cagccctttt gggaatgttg cctaagggaa ttgccctttt gaccattact
    32641 tcgctcttga ctgcagtgat taagcttggc ttgaaaaagg tcttggtgca ggagatgtac
    32701 tctgttgaga ccttggcgcg cgtggatatg ctctgtctgg acaagacggg taccatcacc
    32761 caaggaaaga tgcaggtgga ggctgttctt ccactgacgg aaacttatgg tgaagaggct
    32821 gttgccagca tcctgaccag ctatatggcc catagtgagg ataaaaatcc aacagctcac
    32881 gccattcgcc agagattcca aggtcaagta gtctatccta tgctctctaa tcttcccttc
    32941 tccagcgacc gcaagtgggg agccatggag ttagaaggtt tgggaatagt tttcttaggg
    33001 gcacctgaga tgttgctgga ttctgaagtc ccagaagcca gggaggcctt ggagagaggt
    33061 tcacgtgtct tggtcttagc tctcagtcag gagaaattag accatcacaa accacagaaa
    33121 ccatctgata ttcaggctct agccttgctg gaaatcttgg atcctattcg agagggagcg
    33181 gcagagacgc tgaactatct ccgttctcag gaagtggggc tcaagattat ctctggtgac
    33241 aatccagtta cggtatccag cattgcccag aaggctggtt ttgcggacta tcacagctat
    33301 gtcgattgtt caaaaatcac ggatgaggaa ttgattgctc tggcggagga gacagcgatt
    33361 ttcggacgtg tttcccctca tcaaaagaaa ctcattatcc aaacgctgaa aaaagcgggt
    33421 catacaacag ctatgactgg ggatggagtt aatgatatcc tggctcttcg tgaggcggat
    33481 tgttctatcg taatggcgga gggagacccg gcaacccgtc agattgccaa cctggttctc
    33541 ttgaactcag actttaatga tgttcctgag attctttttg aaggtcgtcg tgtggtcaat
    33601 aacattgccc acatcgctcc gattttcttg ataaagacca tctactcatt cttgctcgca
    33661 gttatctgca tcgccagtgc tttactaggt cggtctgaat ggatcttgat tttccccttc
    33721 attccaatcc agattaccat gattgaccag tttgtggaag gtttcccacc attcgttttg
    33781 acttttgagc gaaatatcaa acctgtcgag ccaaacttcc tcagaagatc catgcttcgt
    33841 gccctaccaa gtgccctcat ggtcgtgttt agcgttcttt ttgtgaaaat ctttggaacg
    33901 agtcaaggtt ggtctgagtt agaaatctca actctcctct attatctctt ggggtcaatt
    33961 ggtttcttat ccgtatttag agcctgcatg ccattcactc tatggcgagt cctcttgatt
    34021 gtttggtcag taggaggctt cctagccaca gctctcttcc caagaattca aaaactgctt
    34081 gaaattgcaa ccttaacagg acaaacatta cctgtttatg gtgtcatgat gttggtcttt
    34141 accgtgattt tcatcctgac cagtcgctat caagccagaa aataaagaaa ggctgcaatc
    34201 tgtggattgc ggttttttta ggtacaagat tgccagccga aatgtggtat aataagaggt
    34261 aatagagttt tggaaagtga gagaagatga tttcaaagag attagaattg gtagcttcct
    34321 ttgtgtcaca gggggctatt ttactagatg tgggaagtga ccatgcttat ctgcctatcg
    34381 agttggttga gagaggccaa atcaaaagcg ctattgcagg tgaggtggtg gaaggtccct
    34441 atcagtctgc ggttaaaaat gttgaggctc acggcctaaa ggagaaaatc caagtccgtt
    34501 tagccaatgg cttggcagct tttgaagaga ttgaccaagt gtctgtcatt accattgctg
    34561 gcatgggtgg ttgtttgatt gctaggattt tagaagaagg tttggggaag ttagctaatg
    34621 tagagcgttt gatcctccag cccaataatc gtgaagacga cttgcgtatc tggctacaga
    34681 atcatggatt ccagattgta gcagaaagca tcttagaaga agctggcaag ttttacgaga
    34741 ttttggtggt ggaagcagga caaatgaagc tatcagccag tgatgttcgc tttggtccct
    34801 tcttgtccaa agaagtcagt ccagtatttg tccaaaaatg gcaaaaagaa gctgagaagc
    34861 tagagttcgc cctcggacaa atcccagaaa aaaatctgga agaacgtcaa gttctagtag
    34921 ataagattca agctatcaag gaggtgcccc atgttagcaa gtgaagtgat ccaagcttat
    34981 gaagcctttt gccctcagga attttctatg gagggagaca gccgtggtct gcaaattggc
    35041 actttagaca agggtatcca aagggtcatg gttgccctcg atattcgtga agagacagtg
    35101 gcagaggcca ttgaaaaggg tgtggacttg attatcgtca agcacgcgcc tatctttcgt
    35161 cctatcaagg acttgcttgc cagccgtccg caaaatcaga tttacatcga cctgattaag
    35221 catgatatcg cagtttatgt cagccatacc aatattgata tcgttgaaaa tgggctcaat
    35281 gactggtttt gtcagatgct aggaatcgag gagacgactt atctgcagga aacaggtcca
    35341 gaacgtggaa ttggacgtat tgggaatatt cagcctcaga cattttggga attggcccaa
    35401 caggtcaagc aagtctttga cctagatagc cttcgaatgg tgcattatca agagaatgat
    35461 ttgcagaagc ctatttcaag agtagcaatt tgtggtggaa gcgggcagtc tttctataag
    35521 gatgctttgg caaagggggc agatgtctat atcactggtg atatctacta ccatactgct
    35581 caggatatgc tgtctgatgg cttgttagca ttggatccag gtcactatat cgaagtgctt
    35641 tttgtggaaa aaatcgcagc actccttact caatggaaag agaaaaaagg ctgggaacta
    35701 gagattttac ctagtcaagc atcgaccaat cctttccgtc atatctagtt agaaagtgaa
    35761 gacaatgaaa aaagttgcca ttattggagc aggaattgtg ggagcaacag ctgcctacta
    35821 cctctcgaga gaaagtgacc tagaggtgac cgtttttgac catgagcaag gtcaagccac
    35881 caaggctgca gcaggaatta tcagtccttg gttttccaaa cgccgtaata aagcctggta
    35941 caagatggcg cgcttggggg ctgattttta tgtggattta ttagctgatt tagagaaatc
    36001 aggacaaaaa atcgactttt accagcgttc gggagtcttt ctcttgaaaa aggatgaatc
    36061 caagttggaa gaactttatc aactggccct ccagcgcaga gaagaatctc ccttgatagg
    36121 gcaattagct attctggacc aagcctcagc taatgaatta ttccctggtt tgcagggatt
    36181 tgaccgcctg ctctatgctt ctggtggagc gagagtagat ggccacctct tagtgactcg
    36241 tttgctggaa gccagtcagg tcaagctggt caaagaaaaa gtgactctga caccgttagc
    36301 atcaggctac cagattggtg aagaggagtt tgagcaggtt attttggcga cgggagcttg
    36361 gttgggggac atgttagaac ccttgggtta tgaagtagat gttcgtcctc aaaaaggaca
    36421 actacgagat tatcagctgg tccaagacat ggaagcttac cctgttgtca tgccagaagg
    36481 ggagtgggat ttgattcctt ttgcaggtgg gaaattgtcc ttaggcgcta cccacgaaaa
    36541 tgacatggga tttgatttga cggtagatga aaccttgctc caacaaatgg aggaggccac
    36601 cttgactcac tatctgattt tggctgaagc tacttcaaaa tctgagcgtg tgggaatccg
    36661 tgcctatacc agtgatttct ctcccttctt tgggcaggtg ccagaattgg caggtgtcta
    36721 tgcagccagt ggactaggtt catcaggcct cacaactggt cctatcattg gttaccatct
    36781 agcccaactg atccaagaca aggagttgac cttggaccct ctaaattacc caattgaaaa
    36841 ctatgtcaaa cgagtaaaaa gcgaataata ctcaatgaaa atcaaagaac aaactaggaa
    36901 actagccgcg ggttactcaa agcactgctt tgaggttgtg tatagaactg acgaagtcag
    36961 taaccatacc catggcaagg cgacgttgac gtggtttgaa ttggattttc gaagagtata
    37021 agcattttac tgaaatttta tcaggtagtt taggatggca aatgacattc cctgtcaaaa
    37081 atggtaaaat aagaaaaaat aatctgagaa tcgaggaaaa aagatgcaag aaaagatttt
    37141 ggtaactggt ggtgccggtt ttattggaac ccacactgtt attgaattga tccaagcagg
    37201 ccatcaagtt gttgtggtgg ataatcttgt caatagcaat cgtaagagtt tagaagttgt
    37261 tgaaagaatc acaggagttg agattccttt ctatgaggca gatattcgtg acacagctac
    37321 cctcagagat attttcaagc aggaagaacc gactggtgtc attcactttg ctggtttgaa
    37381 ggctgttggc gaatcaacac gtatccctct tgcctactat gacaacaata tcgctggaac
    37441 tgtcagcctt ttgaaagcca tggaagaaaa caactgtaaa aacatcatct tcagttcttc
    37501 tgcgacagtt tacggggatc cgcacacagt gcccatcttg gaagatttcc cactttcagt
    37561 gaccaaccca tacggtcgta ccaagctcat gctagaggaa attttgaccg atatttacaa
    37621 agcagactca gaatggaatg ttgtcttgct tcgttacttt aacccaatcg gagcccatga
    37681 gagtggtgat ttgggagaaa atccaaacgg tattccaaac aatctcttgc catatgtgac
    37741 tcaagtagcc gttggaaaat tagagcaagt gcaagtgttt ggagacgatt acgatacgga
    37801 agatggaaca ggtgttcgtg actatatcca cgttgtcgat ttggctaagg gtcacgttgc
    37861 agctttgaaa aaaatccaaa aaggttcagg actaaacgtt tataaccttg gaactggtaa
    37921 aggttactca gttcttgaaa ttatccaaaa catggaaaaa gcggtgggac gtcctattcc
    37981 ttaccgcatc gtagaacgtc gcccaggtga tatcgctgcc tgctactcag acccagcaaa
    38041 agctaaagca gaactcggtt gggaagcaga actcgacatc acccaaatgt gtgaagacgc
    38101 atggcgttgg caaagcaagc atccaaatgg atttgaagac taagatgatg atttcaatca
    38161 tcgtcccttg tttaaacgaa gaggaagtac ttcctctttt ttatcaggct ctggaagctt
    38221 tacttccaga tttggaaaca gaaatcgagt atgtctttgt cgatgatgga tcaagtgatg
    38281 ggaccttgga actcttaaag gcctatcggg agcaaaatcc ggcagtccat tatatttctt
    38341 tctctcgaaa ttttggcaaa gaagcagccc tttatgcagg cttgcaatat gcgacaggag
    38401 atttggtggt ggtgatggat gcagacctcc aagatcctcc tagtatgttg tttgagatga
    38461 aaaatgtact agacaaaaat gtagacttgg actgcgttgg gacacggaga actagtcggg
    38521 agggagaacc cttctttcgc agtttctgtg ctgttctctt ttatcgcctc atgcaaaaaa
    38581 tcagcccagt agctctgccg tcgggtgtcc gtgattttcg tatgatgaga aggtctgtag
    38641 tcgatgccat tttaagcttg accgagtcca atcgtttttc aaaggggctc ttcgcctggg
    38701 tgggtttcaa aacctactat ttggactatc caaatgtcga aaggcaggct ggcaagacaa
    38761 gttggagttt taggcaactc tttttctact ccattgaagg gattattaat ttttcagatt
    38821 ttcccttgat tatagccttt gtagctggtc tcctatcttg ttttctttct ctgctgatga
    38881 ccttttttgt tgtggttcgg accctcattt tgggcaatcc gacatctggt tggacctctc
    38941 tgatggctgt tattctcttt cttggaggca ttcaactctt gaccattggg attctcggca
    39001 agtatatcag taagatttat ttagagacta aaaaaagacc actttatctt atcaaagaaa
    39061 aaagtgacct tcctgatttt acagaaaaaa ataaagtgaa aagactataa ttttacatgg
    39121 aaatgtgcta aactagaggg agtggattat cgccattgat ttaggcttcc tggtttccaa
    39181 tcagggcgcg agttgggcaa tttttaacag cctctaagac atcctgacta ggagaaattt
    39241 ctttttccag ttggtcaggg tcatcgtaaa aacgcacgat tccattatcg tggtaatcaa
    39301 ataaatcaga ataagtttgg caaagcccac aggcgataca tcgttcaggt ataagtgtga
    39361 ttttcatgtt catatttata ttgtaataag aaaagtaaaa aaaaacaagg agtaaggtat
    39421 ggcaaaagaa ccgtggcaag aagatatcta tgatcaagaa gaatcaagag cagagcgtcg
    39481 gcatcgaaac cacggagggg ctgataggat ggctaatcgt attttgacga tcctagctag
    39541 tattttcttt gtaattgtgg tggtgatggt catcgttctc atctatctat catcgggggg
    39601 gagtaatcgc acagcagcct taaaagactt tcatgattct gatgcaagtg tagtacaaat
    39661 ctcatcttca agcagttctc agcctgagca gagttcagag ccagaatcta cttctagtag
    39721 ttcagaagaa gctgctaatc ctgaaggaac gattaaagtt ctcgcaggag aaggggaagc
    39781 agctattgcc gctcgtgcag gaatctccat tgctcagtta gaggccttga atcctgggca
    39841 catggctaca ggatcttggt ttgctaatcc aggtgatgtt ataaaaataa aataggagcc
    39901 gatatgaaaa caattcaaat tgctattgat ggtcctgctt ccagcggtaa gagtacggtc
    39961 gcaaagatta ttgctaagga ttttggattc acctaccttg atacaggagc tatgtatcgt
    40021 gcagcgacct atatggctct taagaaccaa ttagtagttg aagaagtcga agcccttcta
    40081 gccttgttgg accagcatcc aatcagcttt ggacgttcag aaactggaga ccagcttgtt
    40141 tttgtaggag atgtggatat tacccatcct atccgtgaaa atgaagtgac caatcatgtt
    40201 tctgctattg cagcaattcc tgaagtgcgt gagaaactgg tttctctcca acaagaaatt
    40261 gcccagcaag gcgggattgt catggatggt cgcgatattg gaactgttgt attgccacaa
    40321 gcagaattga aaattttcct agtagcttct gttgatgaga gagcagagcg tcgttacaag
    40381 gaaaatattg ccaagggaat tgaaacagac cttgaaaccc taaaaaagga aattgctgcg
    40441 cgtgactaca aggatagtca tcgtgagact tctcctctca aacaagcaga ggatgctgtc
    40501 taccttgata caactggttt gaacattcaa gaagtagttg aaaaaatcaa agcagaagct
    40561 gaaaaaagaa tgtaaatgta gaaaagccga tagattgata tcggtttttt tctaaatttg
    40621 tcaaaatgct gattttaggg tataatagtt gctgttcgag aaattttgat tttcaaagaa
    40681 tagtgaatga tgataaggag aaaccatgaa caatttacca aattgtccaa aatgtaactc
    40741 agagtatgtc tacgaagacg gtgccctact ggtttgccca gagtgtgctc atgagtggaa
    40801 tcctgctgaa gttgcagaag tagaagaagg tcttgtcgct atcgatgcca acggaaataa
    40861 attggctgat ggtgatacag taactctcat caaggacttg aaagtaaaag gtgcgccaaa
    40921 agatttgaaa caagggacgc gcgtgaaaaa tatccgcatc gtagaaggcg accacaatat
    40981 cgactgtaag attgatggtt ttggtgccat gaaacttaaa tcagagtttg tgaggaagat
    41041 ttaagcatgt caaaacacta taaacttgta ttttatagcc gtatcttctt gtttctagcg
    41101 gcttttacgg gagtttatct tgaaattact aggcatggtg gttttgggat gcttctctat
    41161 tacacggttc tgtccaacct cttggtaact atttttaccc tttatcttct aaaggttatg
    41221 agccgtgtag gtgaaaattg gcaaaggcca agtctcttgc gcttaaaagg tggggtcacc
    41281 atgagtatca tgattacctg tgtgatttac catttcctct tggcgcccat tgcgactaat
    41341 ttctataccc tagaaaattt cctttgccac tatatcgttc ccatctggtt tttagcggat
    41401 accctctttt ttgacaaaca gggtcaatac aagatttggg atccagcagt gtggaccatt
    41461 ttaccctttc tgtatatgat gtttgctctt tttaatggct tggttctaaa actcaatatt
    41521 ccaaatgcca aggataatcc tttcccttac ttctttttga atgtgaacaa gggttggaat
    41581 gttgtgttta agtggtgtct gattatcttt gttgcctata tggtagcagg atttattttc
    41641 tactttatca agcaaatcaa gagaaagtca tcctaatact cttcgaaaat ctcttcaaac
    41701 cacgtcagtt tccatctgca acctcaaaac actgttttga acaacctgcg gctagcttcc
    41761 tagtttgctc tttgattttc attgagtata agatacaagg gattcatttt cgaatttaag
    41821 aaggagtcta caaaccaatg aggcttcttc ttttcttgct tatttgataa ctatcaaaaa
    41881 agtagaagat taagagaaat atagaaagag atttcatgaa acaattttta gaacgggcca
    41941 gcattttggc tctctccctc gttttgatta cctccttttc catttcgagt gccctaccag
    42001 ccatgtttga ctattatcag ggttattcta aggaacaaat tgagctcttg gtgagcttgc
    42061 cttcctttgg aatcatgatg atgttactgc taaatggttt cttagaaaaa atatttcctg
    42121 agcgcttaca gattagtttg ggcttgctga ttttatcatt gagcggtaca gctcccttct
    42181 ggtaccaagc ctatcccttt gtctttggaa cacggcttct ctttggtttg ggtcttggga
    42241 tgatcaatgc caaggccatt tctattatca gtgaacgcta ccaaggaaaa aggcgaattc
    42301 agatgttagg gctacgcgct tctgcagagg tcgttggagc ttctctcatt accttggccg
    42361 tcggtcagtt gttggccttt ggttggacag ctatctttct agcctatagt gctggatttt
    42421 tggtgctgcc cctttatctg ctctttgtcc cttatggaaa atcaaagaaa gaagtcaaga
    42481 aaagagcgaa ggaagcaagt cgtttaactc gagaaatgaa aggcttgatt tttaccttag
    42541 ctatcgaagc ggcagttgta gtttgtacca atacagctat taccatccgt attccaagtt
    42601 tgatggtgga aagaggattg ggggatgccc agttatctag ttttgttctt agtatcatgc
    42661 agttgatcgg gattgtggct ggggtgagtt tttctttctt gatttctatc tttaaagaga
    42721 aactgctcct ctggtctggt attacctttg gcttggggca aatcgtgatt gccttgtctt
    42781 catccttgtg ggtggtagta gcaggaagtg ttctggctgg atttgcctat agtgtagtct
    42841 tgacgacggt ctttcaactt gtctctgaac gaattccagc taaactcctc aatcaagcaa
    42901 cttcatttgc tgtattaggc tgtagtttcg gagcctttac gaccccattc gttctaggtg
    42961 caattggctt actaactcac aatgggatgt tggtctttag tatcttagga ggttggttga
    43021 ttgtaatctc tatctttgtc atgtacctac ttcagaagag agcttaggat tgattcctaa
    43081 gtttttcttt tgatactcaa tgaaaatcaa agagcatagt tgattgagtt tggaatagta
    43141 cgctgtagct gctaaaatat ttctagaaat taatttgact ttcctaatag agttgttcat
    43201 atcttatttc aatctactat agaaagctag ccgcaggttg ctcaaaatag tgtgttgagg
    43261 ttgcagatgg aaactgacgt ggtttgaaga gattttcaag agtataagat ttttataccc
    43321 atacaatatt tgttttaggt ccttgtttac agactaattt cttgataaaa tagaggttat
    43381 gacgagatat aaagcaacta tttcctatga tggttatgcc tttgctggct ttcagcgcca
    43441 gcctcatgcg cgtagcgttc aggaagaaat tgaaaaaacc ttgaccagat taaataaagg
    43501 gcaaaccatt actgttcacg gtgctggtag gacagatagt ggggttcatg ccctgggaca
    43561 ggtcattcat tttgacctgc cttatcagat ggatgaggag aaactccgtt ttgccttgga
    43621 tacccagtct cctgaagata ttgatgtgat ttcgattgag cttgtggcag ctgattttca
    43681 ttgccgttat gccaagcata gcaagaccta tgagtttatt gtggatagag gacgtcccaa
    43741 aaatccgatg cgccgtcact atgccaccca ctttccctac ccactcgatg tggaacgaat
    43801 gcagattgca atcaaaaagc tagagggaac ccatgatttt accggtttta cagcctctgg
    43861 gactagtgta gaggataagg ttcgcaccat cacagaagct agtttaatag tcgatgagac
    43921 aggacaattt ttgaccttta ccttttcagg aaatggtttc ttgtataaac agattcgcaa
    43981 tatggtgggg actcttctca aaatcggtaa caaccgcatg ccagtagagc agattgatct
    44041 catcttggag aagaaggaca ggcaacttgc aggtcccact gcagcaccaa atggtttgta
    44101 tttaaaggag attcgttatg aagaataatc gtattttagc actttctgga aatgatattt
    44161 ttagtggtgg tggactgtca gctgatttgg ctacctatac cttgaacggc ttgcatgggt
    44221 ttgtagcagt gacttgtttg acagccttga cagaaaaagg atttgaagtc tttccaactg
    44281 atgataccat ttttcaacat gaattagata gcttgcgtga tgtggaattt gggggaatta
    44341 agattggtct tctccctact gtcagtgtgg ctgagaaggc cttggacttt atcaaacaac
    44401 gcccaggaat acctgtggtg ttggatcctg tcttggtctg caaggaaacg catgatgtag
    44461 ctgtcagtga gctctgccaa gagttgattc gctttttccc ttatgtcagt gtgattacgc
    44521 ctaatctccc agaagcagaa ttattatccg gtcaggaaat taaaaccttg gaagacatga
    44581 aaactgcagc gcagaaattg catgatttag gagcgccagc agtcattatc aagggaggca
    44641 atcgtcttag tcaggacaag gctgtggatg tcttttatga tggacagacc tttactatcc
    44701 tagaaaatcc agttatccaa ggccaaaatg ctggtgcagg ttgtaccttt gcctctagca
    44761 ttgccagtca cttgattaaa ggtgataaac ttttgccagc agtagaaagc tctaaggctt
    44821 tcgtttatcg tgctattgca caagcagatc agtatggagt aagacaatat gaagcaaaca
    44881 aaaacaacta aaatcgccct tgtatcccta ttaaccgccc tttctgtggt tctaggttat
    44941 ttcttaaaaa tcccaacacc tacaggaatt ctaactcttt tagatgctgg tgtcttcttt
    45001 gcggcctttt actttggtag tcgtgaagga gcggtagtcg gaggactagc aagtttcttg
    45061 attgacctct tatcaggcta ccctcagtgg atgttcttta gcttggtcaa ccatggcttg
    45121 cagggatttt tcgcaggatt taaaggaaaa agtcagtggt taggccttat tttagcaact
    45181 attgccatgg taggaggcta cgccttgggt tctactttga tgaatgactg ggcagcagcc
    45241 ctcccagaaa ttctaccaaa ttttatgcaa aatatggtag ggatgattgt aggatttatt
    45301 cttagtcaaa gtatcaagaa gattaagtaa tactcttcga aaatctcttc aaaccacgtc
    45361 agcttccatc tgcaacctca aaacactgtt ttgagcagcc tgaggctagc tttctagttt
    45421 gcactttgat tttcattgag tataaagagg ttgagtaaaa agtatttcaa ataagaaaaa
    45481 cgcatagtat aggatgttga aatgatgaac tgccccccaa aagttagaca gaaaaaatct
    45541 aacttttggg gtgttttatt atgaaa
//
LOCUS       DBEJJE010000012        45434 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEJJE010000012 DBEJJE010000000
VERSION     DBEJJE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.12"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            68..388
                     /locus_tag="ACL3F5_000661"
                     /pseudo
     CDS             68..388
                     /locus_tag="ACL3F5_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            509..1453
                     /gene="manA"
                     /locus_tag="ACL3F5_000662"
     CDS             509..1453
                     /gene="manA"
                     /locus_tag="ACL3F5_000662"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0514507.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYVEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     IVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1474..2952)
                     /locus_tag="ACL3F5_000663"
     CDS             complement(1474..2952)
                     /locus_tag="ACL3F5_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0514508.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIDLGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGSSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFEALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE"
     gene            3035..3775
                     /locus_tag="ACL3F5_000664"
     CDS             3035..3775
                     /locus_tag="ACL3F5_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGR0514509.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3804..4259)
                     /locus_tag="ACL3F5_000665"
     CDS             complement(3804..4259)
                     /locus_tag="ACL3F5_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0514510.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4279..5454)
                     /locus_tag="ACL3F5_000666"
     CDS             complement(4279..5454)
                     /locus_tag="ACL3F5_000666"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0514511.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5513..6358)
                     /locus_tag="ACL3F5_000667"
     CDS             complement(5513..6358)
                     /locus_tag="ACL3F5_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0514512.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6483..7040
                     /locus_tag="ACL3F5_000668"
     CDS             6483..7040
                     /locus_tag="ACL3F5_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0514513.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7059..7526
                     /locus_tag="ACL3F5_000669"
     CDS             7059..7526
                     /locus_tag="ACL3F5_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0514514.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7615..8244
                     /gene="upp"
                     /locus_tag="ACL3F5_000670"
     CDS             7615..8244
                     /gene="upp"
                     /locus_tag="ACL3F5_000670"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0514515.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8418..9008
                     /gene="clpP"
                     /locus_tag="ACL3F5_000671"
     CDS             8418..9008
                     /gene="clpP"
                     /locus_tag="ACL3F5_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0514516.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9087..9335
                     /locus_tag="ACL3F5_000672"
     CDS             9087..9335
                     /locus_tag="ACL3F5_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0514517.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9437..10597
                     /locus_tag="ACL3F5_000673"
     CDS             9437..10597
                     /locus_tag="ACL3F5_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0514518.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKS"
     gene            10865..11734
                     /locus_tag="ACL3F5_000674"
     CDS             10865..11734
                     /locus_tag="ACL3F5_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0514519.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11738..12694
                     /locus_tag="ACL3F5_000675"
     CDS             11738..12694
                     /locus_tag="ACL3F5_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0514520.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12694..13458
                     /locus_tag="ACL3F5_000676"
     CDS             12694..13458
                     /locus_tag="ACL3F5_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514521.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13458..14168
                     /locus_tag="ACL3F5_000677"
     CDS             13458..14168
                     /locus_tag="ACL3F5_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514522.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14476..15132
                     /locus_tag="ACL3F5_000678"
     CDS             14476..15132
                     /locus_tag="ACL3F5_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0514523.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15240..16335
                     /gene="prfB"
                     /locus_tag="ACL3F5_000679"
     CDS             join(15240..15311,15313..16335)
                     /gene="prfB"
                     /locus_tag="ACL3F5_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0514524.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16353..17045
                     /gene="ftsE"
                     /locus_tag="ACL3F5_000680"
     CDS             16353..17045
                     /gene="ftsE"
                     /locus_tag="ACL3F5_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0514525.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17038..17964
                     /gene="ftsX"
                     /locus_tag="ACL3F5_000681"
     CDS             17038..17964
                     /gene="ftsX"
                     /locus_tag="ACL3F5_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0514526.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18250..20430
                     /locus_tag="ACL3F5_000682"
     CDS             18250..20430
                     /locus_tag="ACL3F5_000682"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0514527.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20482..21297
                     /locus_tag="ACL3F5_000683"
     CDS             20482..21297
                     /locus_tag="ACL3F5_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0514528.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21437..22780
                     /locus_tag="ACL3F5_000684"
     CDS             21437..22780
                     /locus_tag="ACL3F5_000684"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0514529.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTSQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAIDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            22995..24185
                     /gene="metK"
                     /locus_tag="ACL3F5_000685"
     CDS             22995..24185
                     /gene="metK"
                     /locus_tag="ACL3F5_000685"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0514530.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEVTNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24738..25673
                     /locus_tag="ACL3F5_000686"
     CDS             24738..25673
                     /locus_tag="ACL3F5_000686"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0514531.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25707..26744
                     /gene="holA"
                     /locus_tag="ACL3F5_000687"
     CDS             25707..26744
                     /gene="holA"
                     /locus_tag="ACL3F5_000687"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0514532.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            26917..27522
                     /gene="sodA"
                     /locus_tag="ACL3F5_000688"
     CDS             26917..27522
                     /gene="sodA"
                     /locus_tag="ACL3F5_000688"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0514533.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27680..28210
                     /locus_tag="ACL3F5_000689"
     CDS             27680..28210
                     /locus_tag="ACL3F5_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0514534.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28231..29316
                     /gene="rlmN"
                     /locus_tag="ACL3F5_000690"
     CDS             28231..29316
                     /gene="rlmN"
                     /locus_tag="ACL3F5_000690"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0514535.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29316..29798
                     /locus_tag="ACL3F5_000691"
     CDS             29316..29798
                     /locus_tag="ACL3F5_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0514536.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29800..31341
                     /locus_tag="ACL3F5_000692"
     CDS             29800..31341
                     /locus_tag="ACL3F5_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0514537.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31397..32200)
                     /locus_tag="ACL3F5_000693"
     CDS             complement(31397..32200)
                     /locus_tag="ACL3F5_000693"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0514538.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32284..32505)
                     /locus_tag="ACL3F5_000694"
     CDS             complement(32284..32505)
                     /locus_tag="ACL3F5_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514539.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(32984..33193)
                     /locus_tag="ACL3F5_000695"
     CDS             complement(32984..33193)
                     /locus_tag="ACL3F5_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514540.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSSKPVPKRNMDL
                     LADDSLARDIILLWRIQFGTFTTET"
     gene            33363..33635
                     /gene="rpsP"
                     /locus_tag="ACL3F5_000696"
     CDS             33363..33635
                     /gene="rpsP"
                     /locus_tag="ACL3F5_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0514541.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33655..33894
                     /gene="kphA"
                     /locus_tag="ACL3F5_000697"
     CDS             33655..33894
                     /gene="kphA"
                     /locus_tag="ACL3F5_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0514542.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34043..34367
                     /locus_tag="ACL3F5_000698"
                     /pseudo
     CDS             34043..34367
                     /locus_tag="ACL3F5_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            34471..35259
                     /locus_tag="ACL3F5_000699"
     CDS             34471..35259
                     /locus_tag="ACL3F5_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0514543.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35290..35808
                     /gene="rimM"
                     /locus_tag="ACL3F5_000700"
     CDS             35290..35808
                     /gene="rimM"
                     /locus_tag="ACL3F5_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0514544.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35798..36517
                     /gene="trmD"
                     /locus_tag="ACL3F5_000701"
     CDS             35798..36517
                     /gene="trmD"
                     /locus_tag="ACL3F5_000701"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0514545.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36529..36867
                     /locus_tag="ACL3F5_000702"
     CDS             36529..36867
                     /locus_tag="ACL3F5_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0514546.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36897..37217)
                     /locus_tag="ACL3F5_000703"
     CDS             complement(36897..37217)
                     /locus_tag="ACL3F5_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514547.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37315..37530
                     /locus_tag="ACL3F5_000704"
     CDS             37315..37530
                     /locus_tag="ACL3F5_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0514548.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37736..38272)
                     /locus_tag="ACL3F5_000705"
     CDS             complement(37736..38272)
                     /locus_tag="ACL3F5_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0514549.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(38469..39815)
                     /gene="gor"
                     /locus_tag="ACL3F5_000706"
     CDS             complement(38469..39815)
                     /gene="gor"
                     /locus_tag="ACL3F5_000706"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0514550.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            40080..41279
                     /locus_tag="ACL3F5_000707"
     CDS             40080..41279
                     /locus_tag="ACL3F5_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0514551.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41263..41964
                     /locus_tag="ACL3F5_000708"
     CDS             41263..41964
                     /locus_tag="ACL3F5_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514552.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            41966..43225
                     /locus_tag="ACL3F5_000709"
     CDS             41966..43225
                     /locus_tag="ACL3F5_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514553.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYEFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43349..45346
                     /gene="metG"
                     /locus_tag="ACL3F5_000710"
     CDS             43349..45346
                     /gene="metG"
                     /locus_tag="ACL3F5_000710"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0514554.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        13892 a         8418 c         9909 g        13215 t
ORIGIN      
        1 ttggatttct tctttagttg atttcatatc actattatat aatgcttttt gattttagtt
       61 tagtattatc gtagaaaatg gactcggtgc tatggataca ccggatgaga atggttatgt
      121 agcagataac tatcggatta cttacttaga ggcccacatc aaggccatgc gagatgccat
      181 ttaccaagac ggggttgact tgcttggtta tacgacttgg ggctgtatcg atccggtttc
      241 agctggcaca ggggaaatga ataagcgcta tggctttatc tatgtagatc gagataatgt
      301 aggaaacgga gctctcaaac gtagcaagaa gaagtccttc tattggtaca aggatgtcat
      361 tgatagcaat ggtgcaagca tcgggtagag cacatttgtt tactattttt ataaaatctt
      421 ctccctgctt tataagatgt aaaaaagagt tcaattcgaa ctcttttttt gctataatga
      481 ggggagaaaa atcagacagg agatcgacat gtcagaacca ttatttttac aatcagttat
      541 gcaagaaaaa atctggggtg gagccaagct acgtgatgag tttggctacg acatcccaag
      601 tgaaaaaatc ggagaatatt gggccatctc agcccatcca aatggagtct ctaaagttgc
      661 caatggtcgt tacgagggaa cagatcttgc tactttgtat gtggaacacc gtgaattatt
      721 tggcaatcgt ccagaacctg tatttccact tttgaccaag atcctcgatg ccaacgactg
      781 gctcagtgtc caagttcacc cagacgatgc ttatggactc gagcatgaag gcgaactcgg
      841 aaaaacagaa tgctggtaca ttatcgcagc ggatgaaggt tcagagatta tctacggtca
      901 caatgccaag tcaaaagaag aactccgcca gcaaatcgag gacaagaact gggatgactt
      961 gttgaccaaa gtccctgtta aggctggaga tttcttctat gtaccaagcg ggactatgca
     1021 cgctatcggg gcgggtatct taatccttga aacccagcag tctagcgata ccacctatcg
     1081 cgtctatgac tttgaccgca aggatgacaa aggcaacttg cgtgaacttc atcttgaaaa
     1141 atccatcgat gtcttgaaca ttggtgagcc agcaaatagc cgtcctgtaa ctgttaaagc
     1201 agatgatttg cgttccactc tccttgtatc taatgatttc ttcgcagttt acaagtggga
     1261 aattactgga aaagttgact ttgaaaagac agctgactac agcttattga gtgtcttagc
     1321 tggtcaaggt cagctaattg ttgacgggaa aaattatcca attcaaaaag gcagccactt
     1381 tatcctacca agtgatgttg aagcttggac tctggaaggg caaggtttgg aattgattgt
     1441 tagccatcca taaaaagaaa gggcctgagt ttactactca agtccttttt gattacataa
     1501 attgggcaat gaagaccaca atgatgatga ttggaatgac gaaacgaaga aacgaagaag
     1561 gaagagccag acttggaaca gtccttgttt ccatgctctt tcatcgagat ggagttcctc
     1621 cattgcaaga gcctttttaa agatatagcc tgtaaaaagt gaaaggtaga gagcttcaaa
     1681 tggcatgagg agattggaaa ccaagaagtc catagcgtca aagaaggtct taccaaaaat
     1741 gtgaacatcc gccatgacac cgtaagatag ggctgaagga atgccaaaga caaaggtcaa
     1801 aattcctaaa ataacactcc atttggcacg tttgctgtta tcctggttgg tgatattgcc
     1861 cacattgatc tccagcatca cgacagaaga agtgacagtc gcaaagagga agaggacgta
     1921 gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc aagacgataa agagcaagct
     1981 cgatccccct tcagactgga tattgaaggg ggaccgagct tggaaaatgg ctagacctgc
     2041 catgatggat atcgagatat tcatggctac gatggagatt cctgactgga ctagattggt
     2101 tttcttgtcc aagtaagaag cataggtcaa catgactgta acccctagtg agagggcaaa
     2161 gaaagattgt cccagagcat agaggagacc agcgctagtc agttttgaaa agtctggttt
     2221 gaggaagtaa agaacccctt ccatggcatt tggcaaactg agagagcgac cgatgataac
     2281 aacaaagatg ataaagagca ggggcatcat gactttcgaa gctctttcaa tccctttttg
     2341 aaccccacgt gatacaataa agatatttaa taagataaag gctgcttgag ctcctaggtc
     2401 aatggctgga tttgaaatga ttgaagtaaa taactgagca taatcacccg ttccaccaag
     2461 ttggaacaat ttcccaaact caatacctag atagactaga atccatcctc cgataacact
     2521 gtaaaaagat aagaggataa agagggcaaa ggcgccaatc caaccgataa agttgtactt
     2581 gttattcttg cccagttttc caaaggtttt gatagcggaa acgccagcac tacggccaag
     2641 ggcaaactca gccagcagga gagggaaacc gattaaaata gtggaaatga gaaagattag
     2701 taaaaagcct ccaccgccat tagcagcagt catgtaggga aacttccaaa cggaaccaag
     2761 cccgatgacc gagccagcag atgctagaat aaagccaagt ttcgaccccc attgtgattt
     2821 ttctgacata gttaaactct gatctccttt ttcaaaataa gaaaaagcta cttgagttgt
     2881 caaatagcct tctgtttgat tgatagactt gactatccta ttatgttttc taaggtctgt
     2941 caagaaaacc attttcaagt tttcacacct ttctcaaaaa cgcttgactc tgacctaagg
     3001 ggaggggtta tactatcatt gtaaggagga aatcatgtac catataaaag aagctgcgca
     3061 gctttcaggt gtctctgtca agaccctgca tcactatgac aagataggac tcttggtccc
     3121 cttaaagtcg gaaaacggct atcgaaccta tagtcaagag gatttggaac gccttcaggt
     3181 cattctttac tacaaatatc taggcttttc tttagagaaa atagcagagc tgttaaagga
     3241 agaaaggaca gatttattgc cccatttgac taggcagttg gactatctaa ctcgcgaaag
     3301 gcaacatctg gataccttga tttccacctt gcaaaaaact attcaagaac aaaaaggaga
     3361 aagaaaaatg accattgagg aaaaattcac gggatttagc tatcaagaca atcaaaaata
     3421 ccaccaagaa gcggtagaga aatatggtca agaagtcatg ggacaagcgc tcgaacgcca
     3481 aaaaggtcac gaagacgagg ctacggccgc ctttaaccaa gtctttcaaa ctttggcaca
     3541 aaatcttcaa gttggtttac ctgcaacagc aaccgaaaac caagagcaag cagccaagct
     3601 cttgcaagct attcgcactt atggatttga ctgctctatt gaggtattcg gtcatatcgg
     3661 taaaggttac gtctacaacc cagagtttaa ggaaaacatt gacaagtttg gttctgaaac
     3721 agcccagtac acgtcagatg ccattgcggc ttacgttcag acaaatgcag aataaatagg
     3781 ctaggaattt cctagcctat tttttatttc aaatcataaa gccagtcgtc accgtttttg
     3841 tagtaaaaga attcactgag atcttcttct agaaacacac gaagcatatc agacatatca
     3901 tcggttgcaa gttttagatg agaaagattt tcaaagtcct cccaccaaac tttcccttcg
     3961 tctgaagact ggagttcacc agtaaagtgt tctgtcttgt aaaaaaggac gacataacga
     4021 taatccttgt cgtcatacca gtttttgata ccacagagtt ggggtttgga aatgatcaga
     4081 ccagtttctt ctttcacttc acgaatgaca gcatcgacaa aggattcgcc acgttcaaca
     4141 tgaccaccag gaaaagtaat gccaggccag tcgggactaa ctcggtcttg gaccaggatc
     4201 ttatctccgt ttttaatcat acacatgtta acaaattcga ctgcctctct tctgttcatt
     4261 cttcacaacc tttaatcttt aatcataatg cagacttccc gccacccagc cggtacagag
     4321 ggcagaagtg atgttaaagc cacccgtgtg ggcattgata tccataactt cgcctgcaaa
     4381 gtggaggcca ggtaccagct tactttcaag ggttttagga ttgatttcct tgagactgac
     4441 tccacccttg gtaacaaagg actttgcaag ggacattttt ccagttacag gaattttaag
     4501 ttctttaatg gactggacaa gttgttctcg ttccttttca gtcagctgtt tgactttttc
     4561 aggatatcct tgtacaaaaa attcggccaa gcgttctggt aacaaggttt ttaaagcgtt
     4621 tttcaaggat ttttcccgat tttcttctag aaatgtaacc aagtccttct cagaaagttg
     4681 aggcaaaaca tcgagtgaga gaacctcccc acctttgaca aagctagaca tgcgtagggc
     4741 agcaggacct gacaaaccaa agtgggtaaa gagtaaatca tgagtgatga catgcttacc
     4801 ataacttagg gtcacatcgt ccagagaaat cccttgtaag gctttatgtg gaaaatctgt
     4861 taataaagga ctttcagcag cctcaagatc ggtgatggta tgcttaaaat ggcgagcaat
     4921 ctcgtgacca aaaccagtcg aaccagtcga aggataagac ttaccacctg ttgtgacaat
     4981 gagtttctca caagtgaagg tttgatccgc tgacttaagg acaaactggt catctacttt
     5041 tttaacagaa acgatttcta tttgagtagc aacttgacca cctagttcag tgattttctt
     5101 ttccaaagct tcgataatag tccgagactt gtcactggct ggaaagacgc gtccgtggtc
     5161 ttcgacctta agtttaacac cattttctgt aaaaaagttg atgatgtcat gattatcgaa
     5221 ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga attccagcta gcaggttgtc
     5281 taagctacca ttgttggtca cattgcaacg tcccccacca gtcccagcta atttttttcc
     5341 aagtttccga tttttttcga tgaggagggt tttctgtcca taaaagctac tggaaatcgt
     5401 agccatcata ccagcaggtc ccccaccgat gacaatagta tcaaaatgtt tcatagctct
     5461 attgtaccac aaaaaaacaa gagatgatgg tcacctcttg tcaagaatgc aattaatcaa
     5521 tttcatagcc catcagcaaa ccgccctctt ctgcatagaa actgcagaga ccagaggttg
     5581 gtagaatttt aatatccgct tgtgggaagg tttcacggat tcgctctgag agctgttgac
     5641 aacatttttc gttattgcgt tgggccatga caatacggcc accagcatat ccagctttta
     5701 ctaactcatc ataggcagct tgaactgatt tctttgatcc ccttgctttt tgtagcaatt
     5761 cgagagttcc agtttcacta gcttttccga ccatacgaat gttgagaagg ccaacgaccg
     5821 taccgataag cttgctcaaa cggccgttct tcaccaagtt atcgactttg gctaggacaa
     5881 agagcaactt agttttttct tgataggcag tgatagcttc aaccacttct tcaaaagaca
     5941 agccctggtc aatcaagtca ttcaattttt ctacgagtag gtcaacttca ccaccagcag
     6001 ataaactatc aatcacatga atcttagtgt caggatggtc ttccagataa atattctttg
     6061 ctagttgagc actattgtga ctgccagaaa gggtacctgt gatggttact aggaaaatgt
     6121 ttttggcacc ttcaaatgct cgcaaatagt catctgggct tggacaagcc gattttgaag
     6181 cttctgcagt tgcatacatg gtttccatca tttggtcaat atcgagactg gcgtcatcaa
     6241 caaagacctg atcagctact tgaatggtta aggggacgct tacaaaggtt gtgttaatag
     6301 ctggtgttgg cagttgacga taatcacaac cagagtcagc aataatcttc caagtcatag
     6361 aaattctcca tctttgtcag ttatacattg acaaaggttc tgtctttttt tacaattata
     6421 tcatgaaaac ccttgaaaca aaagcatcat ccgtctgttg tgacaagtag aaagaaaatg
     6481 ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa tctcagaaaa tcaaaccaag
     6541 aatccaattt attaaccaga gaagccattg aaacagccct cttgcaactc ttggaaaaaa
     6601 aggaactgac caagattagt atttctgaat tggtcaaacg tgcaggtgtt tcgcgtgcgg
     6661 ccttttatcg caattatgac tccaaagagg aaattttaga gagcgtcttt aaacgaactg
     6721 tccacaatat tatggaacag ctgcatcatt acgatttaaa gacagacctt tatttggttt
     6781 gggttcacct tttccgggag gccagaaagg aagctagagt aattcaattg gccttggatt
     6841 accatctgga aaaaatcttt gtccaagcca tgcaggaatt tctagaaaaa taccatggga
     6901 aatcaaaagg tgtcagctct tatcttcatt ccttctggag ctcagccatc gtctctgtcc
     6961 ttctaaaatg gatcaaggat ggcatgaagg taccagctga aaagattgca gatttaggtt
     7021 taccattttt taaaaaatag agaaaaagga gaaaagagat gactgaaaaa agactggcct
     7081 gggatgagta ttttgcagcc caagccctac taattgcgaa tcgttccact tgtaaacgtg
     7141 ctaaagtggg cgcgattctg gtaaaagata ataaggttat ttccactggt tacaatggtt
     7201 cggtgtcagg gactgagcat tgtattgatc acgaatgttt ggtcattgaa ggccactgtg
     7261 ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg tgctgagcgt ggtgttccca
     7321 aaggctttac agcctatgta acccattttc cttgtctcaa ctgtacaaaa caattgcttc
     7381 aggtcggctg caagcgtgtg gtttatatca accagtaccg aatggacgac tacgcccaat
     7441 acctttatca agaaaaaggg acagaattga cccatttacc acttgagaca gtacagacag
     7501 ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat aaatggttta gaaagatttt
     7561 taaaccgttt tttggtataa taagaagaat aaattgaaag aaggaattcc aaaaatggga
     7621 aaaattgaag ttattaatca cccactgatt caacacaaat tgtcaatctt gcgtcgtaca
     7681 gatacttcta caaaagcttt tcgtgagcta gtagatgaga ttgcaatgtt gatggggtat
     7741 gaagtacttc gtgatcttcc actagaagat gtggaaatcg aaacaccaat tacaaaaaca
     7801 gttcaaaaac aattggcagg taagaaattg gccatcgtcc caatcttgcg tgcaggtatc
     7861 gggatggttg atggtctctt gagcttggtt ccagctgcta aagttggcca catcggtatg
     7921 taccgtgatg aagaaacact tcaaccagtt gaatacttgg tgaaattgcc tgaggacatt
     7981 gaccaacgtc aaatttttgt agtagaccca atgttggcaa caggtggctc agcaatcttg
     8041 gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca aatttgtctg ccttgtatct
     8101 gctccagagg gtgtaaaagc ccttcaagaa gctcatccag atgtagaaat ctttacagca
     8161 gccttggatg aacgtttgaa cgaacacggt tatatcgttc caggtcttgg agatgctgga
     8221 gaccgcttgt tcggtacaaa ataagatcga aaagaagaat gacttggaaa agtatttcca
     8281 gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa agcagagcaa aaatttgacc
     8341 ttttttgacc aagatattat aatagtctta tcttcagtca tttgaccaac aaaattaaaa
     8401 ctcaaaagga gaaatgaatg attcctgtag ttattgaaca aacaagccgt ggagaacgtt
     8461 cttacgatat ttactcacgt cttctcaaag accgcatcat tatgctgaca ggtccggttg
     8521 aagacaatat ggctaactct gttattgccc aactgctttt cttggatgcc caagatagta
     8581 caaaagatat ttacctttat gtcaatacac caggtggttc tgtttcagct ggtttggcaa
     8641 tcgtagatac catgaacttt atcaaggcag atgtccaaac cattgttatg ggaatggctg
     8701 catctatggg aacagtcatc gcatcaagtg gagcaaaagg caaacgtttc atgcttccaa
     8761 atgctgaata catgattcac caaccaatgg gcggtacagg tggtggtacc caacaaactg
     8821 atatggctat cgctgcagaa cacttgctca aaactcgtaa taccttggaa aaaatcttgg
     8881 ctgaaaattc aggtcagtca atggaaaaag tccatgcaga tgcagaacgt gataactgga
     8941 tgagcgccca ggaaacactt gaatatggct ttattgatga aattatggcc aacaattcat
     9001 tgaactaatg atgatagaag gcaaactcga ctgggtttgc tttttttggt ataataggga
     9061 gagatttctt agaaagagga tttatcatgt ttgaaaaagt caatcgctct ggcttgatta
     9121 tctatcttta ctataatcgt gatgccaaaa aactgcagga ttatggagat attacctatc
     9181 attccaagaa acatcgttac ttacaactct atgttccaac tcaagaagtg gagcaattgg
     9241 tcggacgctt gagcaaggaa aaatttatta aaaaagttag ggtttgtcat atccaagagt
     9301 tggaaacacc ctttgtgggc aatctttatc gataggaaaa cgttatcatc gaaaaagttc
     9361 aaggaaaaca ttgacaattt tctgataatt cggtatattc ttaacagact atttaagaaa
     9421 taaggagaca aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt
     9481 agcacttctt gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc
     9541 agtagaggaa aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc
     9601 atacggaaca gctgaacaaa aaggtgccca attggctgtt gatgaaatca atgccgcagg
     9661 tggtatcgat ggaaaacaaa tcgaagtaat cgataaagat aataagtctg aaacagctga
     9721 ggctgcttca gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc
     9781 tgcgacatct ggtgcgactg cagctgcggt agcgaacgct acaaaagcag gtgttccatt
     9841 gatctcacca agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg
     9901 aactttccaa gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa
     9961 tgctaagaaa gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa
    10021 atctttccgc gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga
    10081 cacagacttc caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt
    10141 tcctggttac tataatgagg ctggtaagat tgtaaaccaa gcgcgtggca tgggaattga
    10201 caaaccaatc gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc
    10261 tgaaaaagca tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc
    10321 taaagctaaa gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt
    10381 tgcagccttg gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa
    10441 ttcaggtgaa atcaagaata accttgctaa aacaaaagat tttgaaggtg taactggtca
    10501 aacaagcttc gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa
    10561 tggtaaagtt gaagcagcag aagttgtaaa atcataatag aaaaatgttg aaatagggaa
    10621 tgagcctttg actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact
    10681 gcgtcaacgt cgccttggat tatatatgtg actgacttcg tcagtcttat ctacaacctc
    10741 aaagcagtgc tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
    10801 gtataagaac ctatcaaaaa gtgagggaaa accctcggaa ttataaatag aaagagtgaa
    10861 tcttatgctc caacaactcg taaatggttt gattctaggt agtgtttacg cgctgttagc
    10921 cctaggatat accatggttt acggaattat caagctcatc aacttcgccc atggtgatat
    10981 ttatatgatg ggagccttta tcggttattt cttgatcaat tctttccaaa tgaatttctt
    11041 tgtagcgctt attgtagcta tgctagcgac agctattctt ggtgtcgtga ttgagtttct
    11101 tgcttaccga cctttgcgcc actctactcg tattgctgtt ttgattacgg ctattggggt
    11161 ttctttccta ttggagtatg gaatggtcta tctggttggt gccaataccc gtgccttccc
    11221 tcaagcgatt caaacagttc gatatgattt gggaccaatt agcttaacaa atgtgcagtt
    11281 aatgattttg gccatttcct tgattttgat gattttgtta caagtcattg tccaaaagac
    11341 taagatgggg aaagccatgc gtgcagtatc agtagatagc gacgcggcac aattgatggg
    11401 gatcaatgta aaccgtacga ttagctttac cttcgctttg ggttctgctc ttgcgggtgc
    11461 ggctggtgtt ctgattgctc tttattataa ctctcttgag cctttgatgg gggttactcc
    11521 aggtcttaaa tctttcgttg ccgcagtact tggtggtatc ggaattattc ctggtgcggc
    11581 tcttggtggc tttgtgattg gtctattgga aacctttgcg acagcctttg ggatgtcaga
    11641 tttccgtgat gccattgttt atggaatctt gttgttgatc ttgattgtcc gcccagctgg
    11701 tatccttggt aagaatgtga aagagaaggt gtaaacgatg aaggaaaatt taaaagttaa
    11761 tattctatgg ttactccttt tgttagctgg ctatagcttg attagtgtac tggtttcagt
    11821 cggagtactt aatctattct atgtacagat tttacaacaa attggaatta atattatttt
    11881 ggctgttggt ctcaacttaa tcgttggttt ttcaggacaa ttttcacttg gtcatgctgg
    11941 tttcatggcg attggtgcct atgccgcagc tattattggt tctaaatcac caacctacgg
    12001 tgccttcttt ggagctatgc ttgtaggggc tttgctttca ggagcagttg ccttacttgt
    12061 cggcattcca accttgcgct tgaaggggga ctatcttgcg gtagcaactc tgggtgtttc
    12121 tgaaattatc cgtatcttta tcatcaatgg tggaagtctt acaaatggtg cggcaggtat
    12181 cttagggatt cctaacttta caacttggca aatggtttac ttctttgtcg tgattacaac
    12241 cattgcaacc ttgaacttct tgcgtagccc aattggccgt tcaaccctct ctgttcgtga
    12301 agatgaaatc gctgctgagt cagttggggt taatacgact aaaattaaaa tcatcgcttt
    12361 tgtctttggt gccattactg caagtattgc tgggtcactt caggcaggat ttatcgggtc
    12421 tgttgtaccg aaagattaca ccttcatcaa ctcaatcaac gttttgatta ttgttgtatt
    12481 tggtggactc ggttccatta caggtgcgat tgtttcggct attgttctgg gaattttgaa
    12541 tatgcttctc caagatgttg ctagtgtgcg tatgattatt tacgctttgg ccttggtatt
    12601 ggtaatgatt ttcagaccag gtggactcct tggaacgtgg gaactgagcc tatcacgttt
    12661 ctttaaaaaa tctaagaagg aggaacaaaa ctaatggcat tacttgaagt aaaacagtta
    12721 accaaacatt ttggtggtct aacagctgtt ggagatgtga ctcttgaatt gaacgaaggg
    12781 gaactggttg gattaatcgg tccaaacgga gctgggaaaa ccaccctttt caaccttttg
    12841 accggtgttt atgaaccaag cgagggaaca gtaaccctag atggtcacct tttgaatggg
    12901 aaatcacctt ataagattgc ctctttggga cttggacgta ctttccaaaa tatccgtctc
    12961 tttaaagatt taacagtttt agataatgtt ttgattgctt ttggaaacca tcacaaacag
    13021 catgttttta ctagtttctt acgcttacca gctttttaca agagtgaaaa agaattaaag
    13081 gctaaagctt tggaattgtt gaaaatcttt gatttagatg gtgatgcaga gactcttgct
    13141 aaaaatcttt cctacggaca acaacgtcgt ttggaaattg ttcgtgccct tgctacggaa
    13201 cctaaaattc tcttcttaga tgaaccagca gcaggtatga acccacagga aacagccgaa
    13261 ttgactgagt taattcgtcg tatcaaagat gaatttaaga ttacaatcat gttgattgaa
    13321 cacgatatga atctggtcat ggaagtaaca gaacgtatct acgtacttga atatggccgt
    13381 ttaattgctc aaggaactcc agacgaaatt aagaccaata aacgcgttat cgaagcttat
    13441 ctaggaggtg aagcctaatg tctatgttaa aagttgaaaa tctttctgtg cattacggta
    13501 tgatccaagc agtccgtgat gtaagctttg aagttaatga aggagaagtt gtttccctta
    13561 tcggtgccaa cggtgcaggt aagacaacta ttcttcgcac cttgtcaggt ttggttcgac
    13621 caagttcagg aaagattgaa tttttaggtc aagaaatcca aaaaatgcca gctcagaaaa
    13681 tcgtggcagg tggtctttca caagttccag aaggacgcca cgtctttcct ggcttgactg
    13741 ttatggaaaa tcttgaaatg ggagctttct taaagaaaaa tcgtgaagaa aatcaagcta
    13801 acttgaagaa ggttttctca cgctttcctc gtcttgaaga acggaagaac caagatgcag
    13861 ctactctttc aggaggggaa caacaaatgc ttgccatggg acgcgctctt atgtcaacac
    13921 caaaacttct tcttttagat gaaccatcaa tgggacttgc cccaatcttc atccaagaga
    13981 tttttgatat cattcaagat attcagaagc aaggaacaac cgtcctcttg attgaacaaa
    14041 atgccaataa agcactcgca atctctgacc gaggatatgt attggaaaca ggaaaaatcg
    14101 tcctatcagg gacaggaaaa gaactcgctt catcagaaga agtcagaaaa gcatatctag
    14161 gtggctaaaa caatccagtg gattgtttta gtcggcagat gaagattacg aagtaatcat
    14221 caatatagtc cgggggacct ttttagtcgg tggatagaga ttgcaaacaa atatgcatct
    14281 acattgaaag cttaatttct aataattgaa aaaatcgaat gaaaaatttc ttaccttcat
    14341 tcacagagct ctatttcaga gctctttttg ctagcttatt catacttttt tgaatttcga
    14401 aaaagaaatg taagcgtttg atagatttac aaaaagattg tataatgggg ataagaatag
    14461 aaaaggagaa gtctcatggc agttaaagat tttatgaccc gcaaggtagt ttatattagt
    14521 ccagatacaa cagtatctca tgcagcagat ttgatgagag agcaaggttt gcaccgtctg
    14581 cctgttatcg aaaatgatca attagttggt ttggtgactg agggaaccat tgcacaagca
    14641 agtccatcta aagcaacaag tctttctatc tatgagatga attatcttct gaataagaca
    14701 aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct caggctatgc tagtctagaa
    14761 gatgcaactt atctgatgtt gaaaaataag attggtattc tccctgtcgt agataaccat
    14821 caagtatacg gagttattac tgaccgtgat gttttccaag cctttcttga aattgcaggt
    14881 tatggcgaag aagggattcg tgtacgcttt gttacagaag atgaagttgg tgttcttgga
    14941 aaaattgttt ctttgattgt agaagaaaat ttgaatatct cccatacagt caatattccg
    15001 cgtaaggatg gtaaggtgat tatcgaagtg caaatcgatg aatcaattga tttaccagcc
    15061 ttgaaagaaa aatttgaagc aaatggtatt caagtggaag aaatcgctcg cacttcagca
    15121 aaagtcttgt aagaagggaa gtccaaaggc ttcttttttc atgaaaaggg gattagagca
    15181 aaagatggaa agaaatgata aaatatgcta taatgaaata atgtaaaaaa ggagtattta
    15241 tggacatttc agtaattcgt cagaaaattg acgcaaatcg tgaaaaatta gcttctttca
    15301 gggggtctct ttgacctcga agggctagag gaagagattg ccatcttgga aaacaagatg
    15361 acagaacctg atttttggaa cgataatatt gcggcccaaa aaacgtcgca agaattgaat
    15421 gaattaaaaa acacttacaa taccttccat aagatggaag agttgcagga tgaagtcgaa
    15481 attttattgg attttttggc tgaagacgag tcagtgcatg atgaactggt agcgcaatta
    15541 gccgaacttg ataagataat gaccagctac gagatgactc tactcttgtc agaaccttat
    15601 gaccacaaca atgccatctt ggaaatccat ccaggttctg gtggtactga ggcgcaggac
    15661 tggggtgata tgttgcttcg tatgtatact cgttatggta atgctaaagg ctttaaagtg
    15721 gaagtgttgg attaccaagc aggtgatgag gctggtatta agtcggtaac tttatcattt
    15781 gaagggccta atgcctatgg tctcctcaag tcagaaatgg gtgttcaccg cttagtgcga
    15841 atctcaccat ttgactctgc caaacgtcgc catacctctt tcacatctgt agaagtgatg
    15901 ccagaattgg atgatactat tgaagtggaa atccgtgaag atgatatcaa gatggatacc
    15961 ttccgttcag gtggtgccgg tggacaaaac gtcaataagg tttcaacagg tgtacgttta
    16021 acccacattc caactggaat tgttgtccaa tcaacagtgg atcgtaccca gtatggaaat
    16081 agagatcgtg ccatgaagat gttgcaggct aagctctatc aaatggagca agataagaag
    16141 gctgcggagg tagattctct caaaggtgag aaaaaggaga tcacttgggg aagccaaatc
    16201 cgttcttatg tcttcacgcc ttatactatg gtaaaagatc accgaactag ctttgaggtt
    16261 gctcaggtag ataaggttat ggatggggac ctagatggtt ttatcgatgc ttatctcaag
    16321 tggcgaatta gctaagatag aaaggaactc acatgtcaat tattgaaatg agagatgtcg
    16381 ttaaaaaata cgacaacgga acgactgctc tacgcggtgt ttcggtcagc gttcaaccgg
    16441 gggaatttgc ttacatcgta ggaccttcag gagcagggaa gtcaactttt attcgttctc
    16501 tgtatcgtga agtaaaaatc gataaaggaa gtctatcagt tgctggtttt aatctggtta
    16561 agatcaaaaa gaaagatgtc ccgcttctac gtcgtagtgt tggggttgtc ttccaagatt
    16621 ataaattgtt accaaagaaa actgtctatg aaaatattgc ttacgctatg gaagtaatcg
    16681 gggaaaatcg ccgtaatatc aaaagacgag tgatggaagt tttggacttg gttggattga
    16741 agcataaggt tcgttctttc ccaaatgaac tctcaggtgg ggagcaacag cgaattgcga
    16801 ttgcgcgtgc aattgtaaat aatcccaaag tattgatagc tgatgagcca acaggaaatc
    16861 tggatccgga taattcatgg gaaattatga atctcttgga acggattaac ctacaaggaa
    16921 caactatttt gatggcgact cataatagcc agattgtaaa taccttgcgc caccgtgtca
    16981 ttgccattga aaatggccgt gtcgttcgtg acgaatcaaa aggagagtat ggatacgatg
    17041 attagtagat tttttcgcca tttatttgaa gccttaaaaa gtttgaaacg aaatggttgg
    17101 atgacagtag ctgctgtcag ttcagtcatg attactttga ccttggtggc aatatttgca
    17161 tctgttattt tcaatacagc gaaactagct acagatattg aaaataatgt ccgtgtagta
    17221 gtttatatcc gaaaggatgt ggaagataat agtcagacaa ttgaaaaaga aggtcaaact
    17281 gttacaaata atgactacca caaggtatat gattctttga agaacatgtc tacggttaaa
    17341 agtgttacct tttcaagtaa agaagaacaa tatgaaaaat taaccgagat aatgggagat
    17401 aactggaaaa tctttgaagg agatgccaat cctctctatg atgcctatat tgtagaggca
    17461 aacactccaa atgatgtaaa aactatagcc gaagatgcta aaaaaattga aggtgtctct
    17521 gaggttcaag atggcggtgc caatacagaa agactcttca agttagcttc atttatccgt
    17581 gtttggggac tagggattgc tgctttgtta atttttatcg cagttttttt gatttcaaat
    17641 accattcgta ttaccattat ttcccgcagt cgcgaaattc aaatcatgcg cttggtcgga
    17701 gctaaaaaca gttatatccg tggaccgttc ttgttagaag gagcctttat cggtttattg
    17761 ggagctatcg caccatctgt tttggtcttt attgtttatc aaattgttta ccaatctgtc
    17821 aacaaatcgt tggtagggca aaatctatcc atgattagtc cagatttatt tagtccgttg
    17881 atgattgccc tactatttgt gattggggtt ttcattggtt cattgggatc aggaatatcc
    17941 atgcgccgat tcttgaagat ttaggtaaaa tagctgcttt tatgaggaga ttgcaaaatc
    18001 tccttttttg ctacaagagt ttttgaaaag agatgcgcag aagaaaagag cttccaaaga
    18061 agtcccccag agaagacttc ttgatggcta atttgaactt gaaatttggc gcactagaaa
    18121 ttttttagaa aaaagtgtaa tttttttata aaagccttta caaaaaaaat taaagtggta
    18181 taattaaatc atagaaagtg caaacgtttt cgtaaaacgt ttgcctaaat aaaaataaag
    18241 gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt ctttcgaatt ttggcaaaaa
    18301 ttcggtaagg ctttgatggt agttatcgcg gttatgccgg ctgctggttt gatgatttca
    18361 atcggtaagt ctatcgtgat gattaaccca acctttgcac cacttgtcat cacaggtgga
    18421 attcttgagc aaatcggttg gggggttatc ggtaaccttc acattttgtt tgccctagcc
    18481 attggaggaa gctgggctaa agaacgtgct ggtggtgctt tcgccgctgg tcttgccttc
    18541 atcttgatta accgtatcac tggtacaatc tttggtgtat caggcgatat gttgaaaaat
    18601 ccagatgcta tggtaactac tttctttggt ggttcaatca aagttgctga ttactttatc
    18661 agtgttcttg aagctccagc cttgaacatg ggggtattcg tagggattat ctcaggtttt
    18721 gtaggggcaa ctgcttacaa caaatactac aacttccgta aacttcctga tgcactttca
    18781 ttcttcaacg ggaaacgttt cgtaccattt gtagttattc ttcgttcagc aatcgctgca
    18841 attctacttg ctgctttctg gccagtagtt caaacaggta tcaataattt cggtatctgg
    18901 attgccaact cacaagaaac tgctccaatt cttgcaccat tcttgtatgg tactttggaa
    18961 cgtttgctct tgccatttgg tcttcaccac atgttgacta tcccaatgaa ctacacagct
    19021 cttggtggta cttatgacat tttaactggt gcagctaaag gtactcaagt attcggtcaa
    19081 gacccactat ggcttgcatg ggtaacagac cttgtaaacc ttaaaggtac tgatgctagt
    19141 caataccaac acttgttaga tacagtacat ccagctcgtt tcaaagttgg acaaatgatc
    19201 ggttcattcg gtatcttgat gggtgtgatt gttgctatct accgtaatgt tgatgctgac
    19261 aagaaacata aatacaaagg tatgatgatt gcaacagctc ttgcaacatt cttgacaggg
    19321 gttactgaac caatcgaata catgttcatg ttcatcgcaa cacctatgta tcttgtttac
    19381 tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg taaacctacg tatgcactca
    19441 ttcggttcaa tcgagttctt gactcgtaca cctattgcaa tcagtgctgg tattggtatg
    19501 gatatcgtta acttcgtttg ggtaactgtt ctctttgctg taatcatgta ctttatcgca
    19561 aacttcatga ttcaaaaatt caactacgca actccagggc gcaacggaaa ctacgaaact
    19621 gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg cagcaggttc tcaagctgta
    19681 aacattatca accttcttgg tggacgtgta aacatcgttg atgttgatgc atgtatgact
    19741 cgtcttcgtg taactgttaa agatgcagat aaagtaggaa atgcagagca atggaaagca
    19801 gaaggagcta tgggtcttgt gatgaaagga caaggggttc aagctatcta cggtccaaaa
    19861 gctgacatat tgaaatctga tatccaagat atccttgatt caggtgaaat cattcctgaa
    19921 actcttccaa gccaaatgac tgaagcacaa caaaacactg ttcacttcaa agatcttact
    19981 gaggaagttt attcagtagc agacggtcaa gttgttggtt tggaacaagt aaaggatcca
    20041 gtatttgctc aaaaaatgat gggtgatgga tttgcagtag aacctgcaaa tggaaacatt
    20101 gtatctccag tttcaggtac tgtgtcaagc atcttcccaa caaaacatgc ttttggtatt
    20161 gtgacggaag caggtcttga agtattggtt cacattggtt tggacacagt aagtcttgaa
    20221 ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag ttgcagcagg agatctcctt
    20281 gtcacagctg acttggatgc tatccgtgca gcaggacgtg aaacttcaac agtagttgtc
    20341 ttcacaaatg gtgatgcaat taaatcagtt aaattagaaa aaacaggttc tcttgcagct
    20401 aaaacagcag ttgctaaagt agaattgtaa tatacttgag gttggaagct gtattccaac
    20461 ctcttatttt gggagaaaag aatgaaattt ttaacactca atactcacag ttggatggag
    20521 aaagaagcag aggaaaaatt ccagattttg cttgaagata ttcttgaaaa ggactatgat
    20581 ttgatttgtt tccaagaaat caatcaggag atgacctcgt cagaggtgga ggttaatgac
    20641 ctttatcaag ctttgccagc agctgagcct attcaccaag accattatgt tagactcttg
    20701 gttgaaaagt tgttagagca agggaaaaat tactactgga cctgggctta taaccatatc
    20761 ggctatgacc gctaccacga aggtgtggct atcttgtcta aaacacctat tgaagccaga
    20821 gaaattttgg tttcagatgt ggatgatcca acagactatc atactcgccg tgttgcccta
    20881 gctgaaactg tagtcgatgg caaggagcta gcagttgcca gtgttcatct ctcttggtgg
    20941 gataaaggtt tccaagaaga atgggcacga tttgaggctg tcttgaaaaa attgaacaag
    21001 ccacttttac tagctggaga ttttaacaac ccagcaggtc aggaaggtta ccaagctatt
    21061 ttagctagtc cattaggctt acaagacgca tttgaagttg ctcaagagaa aagtggtagc
    21121 tatactgttc cgcctgaaat tgatggctgg aaagggaaca ctgaacccct tcgaatcgat
    21181 tatgtcttta ctaccaaaga gttagcggtg gaaaatttac atgtcgtatt tgatggtaac
    21241 aagagtccac aagtgagtga tcactatggc ttgaatgcta tattaaactg gaaataataa
    21301 ctgaaaagag gttggaacta taaaattcca gccttttctt actagagaag ctactggaaa
    21361 tagcctaaat aagtgagact actgtaatgg aataaaatat ggtataattg ataagataga
    21421 tagaatcgag gatgttatgt catttacgaa atttcaattt aaaaactata ttagagaagc
    21481 cttgaaggag ttaaaattta caactccaac agaggtgcaa gacaagttga ttcctattgt
    21541 tttggcaggt cgtgacctag taggagaatc aaaaacaggt tcaggtaaga ctcatacttt
    21601 cttgttaccg attttccagc aattagatga agctagcgat agtgtacaag cagtgattac
    21661 tgcaccgagt cgtgagttgg ctactcaaat ttaccaagta gcgcgtcaga tttcagctca
    21721 ctcagatgtc gaagttcgtg tggttaatta tgtgggtggt acggataagg ctcgccagat
    21781 tgagaaattg gcaagcaatc agcctcatat tgttattgga acaccaggcc gtatctacga
    21841 cttggttaaa tctggtgatt tagctattca taaagccaag acatttgttg ttgatgaagc
    21901 agatatgacc ttggatatgg gattcttgga aactgttgat aagattgctg gcagtcttcc
    21961 aaaagacttg caattcatgg tcttctcagc gactatccca caaaaactgc aaccattctt
    22021 gaaaaaatac ttatcaaatc ctgttatgga gaaaattaag accaaaacgg ttatttctga
    22081 caccattgat aattggttga tttcgaccaa gggacatgat aagaatgctc aaatttacca
    22141 gttgactcag ttgatgcagc cgtatttggc aatgattttt gttaacacta aaacgcgtgc
    22201 tgatgaattg cattcatatc tgacttctca aggtttgaag gttgcaaaaa tccatggcga
    22261 tattgcccct cgtgaacgca agcgaatcat gaatcaggtg caaaatctgg attttgagta
    22321 tattgtcgca acagatttag cagcgcgtgg gattgacatt gaaggtgtca gccatgtcat
    22381 caatgatgcc attccgcaag acttatcttt ttttgttcac cgtgttggtc gtactggacg
    22441 aaatggccta ccaggtacag ctattaccct ttatcagcca agtgatgact cggatatccg
    22501 tgagttggag aaattgggaa tcaagtttag tcctaagatg gtcaaagacg gggaatttca
    22561 agatacctat gaccgtgatc gtcgtgccaa ccgtgagaaa aaacaagata aacttgatat
    22621 cgaaatgatt ggtttggtta aaaagaaaaa gaaaaaagtc aaaccgggtt ataagaagaa
    22681 aattcaatgg gcgattgatg aaaagcgccg taaaaccaag cgtgctgaaa atcgcgctcg
    22741 cggccgtgca gagcgtaaag ctaaacgcca aacattttaa tagaaattgt tggagtattg
    22801 agctccaact ttttgcttta tgagaacgaa ctatctaaac cgaaacacta cattaaagac
    22861 tgcaaattgc gattaaaaat ggtataatga taaagttata tagtcccgat aagatggtag
    22921 gtatttatta cgaagagttt tcctatcagt actttgtaac tctataacaa tattttttaa
    22981 ggggggacat ttttatgtca gagcgtaaat tattcacgtc tgaatctgta tctgaggggc
    23041 atccggataa gattgcagac caaatttcag atgcgatttt ggatgctatt ttagcaaagg
    23101 atccagaggc gcacgttgct gctgaaacag ctgtatatac tggttctgtc cacgtttttg
    23161 gtgaaatttc tacaaatgcc tatgtggata ttaaccgtgt ggttcgtgat accattgcag
    23221 agattggtta taccaataca gaatatggat tttctgctga gacggtggga gtacacccat
    23281 ctttggtgga acaatctcct gacatcgctc aaggtgttaa cgaagccttg gaggttcgtg
    23341 gaaatgctga tcaagatcca ctggacttga ttggagcagg tgaccaaggg ctcatgtttg
    23401 gatttgcagt agatgaaaca gaagagctca tgccattgcc aattgcactt agtcataaat
    23461 tggttcgtcg tctggcagaa cttcgtaagt ctggagaaat tagctatctc cgtccagatg
    23521 caaaatcaca agttacagtt gagtacgatg aaaatgaccg tccggtacgt gtagatacag
    23581 tcgttatttc tactcagcat gatccagagg tcactaatga acaaatccat caagatgtga
    23641 ttgacaaggt catcaaagaa gttattccat cttcttatct tgatgataag acaaaattct
    23701 ttatcaatcc gacaggtcgt tttgtaatcg gtggtcctca aggggactca ggtttgactg
    23761 gtcgtaagat tattgtagat acttatggtg gctactctcg tcatggtggt ggtgccttct
    23821 ctggtaaaga tgcgactaag gtggatcgtt cagcctctta tgcggctcgc tatattgcca
    23881 agaatatcgt tgcagcagac cttgctaaga aggcagaagt gcagttggcc tatgctatcg
    23941 gtgttgcgca acctgtttct gttcgtatcg atactttcgg tacaggaaca gtagctgaaa
    24001 gtcaacttga aaaagcggct cgtcaaatct ttgaccttcg ccctgcaggg attatacaaa
    24061 tgctggacct taagcgtcca atttaccgtc aaacatcggc ttacggtcac atgggacgta
    24121 cagatattga tcttccatgg gaacgtttgg ataaggtaga tgctttgaaa gaagcagtaa
    24181 aataagattt taagagggga acgtcctctc ttttttatag tttttaacta tactgggata
    24241 ctgttctgaa aatccatttt gtgaaagtag agatttacat gtatagtaga ttgaaactag
    24301 aatagtacac ctcaacttct aaaacattgt tagaaatcga tttgactgtc ctgattgatt
    24361 tctcctgttc ttgtttcatt ttactatatt tctttaaaaa tgataaaggt tgagatttct
    24421 cctcgtaata gataatcatg gggatatttc aatccaaagt tttattcgtt atcacttgac
    24481 tattgcaagg ttttctagag caacagagtc atggaatgga ctcatggttg agatttctcc
    24541 ttgttgcttg gacttcattc aaaagtctgt tacccaagcc ttgttcaaac ttccaataca
    24601 ctagctgttt ccatagcatg acttctgtac tagactttct tttccgaata aatagataga
    24661 accacagaat ctagtaaacc tagaattaaa attatggtat aatattagca ataaaagaaa
    24721 tctggaggat tagaatcatg gtatcaacga aaacacaaat tgctggtttt gagtttgaca
    24781 attgcttgat gaatgcagca ggtgtggctt gtatgacgat agaggagtta gaagaggtca
    24841 aaaactcagc ggcaggaacc tttgttacta agacagcgac cttggacttc cgtcagggga
    24901 atcctgagcc acgctaccaa gatgttccac ttggttccat caactctatg ggcttgccaa
    24961 ataatggctt agactattat ttggattatc ttttagattt gcaggaaaaa gagtcgaacc
    25021 gaactttctt cttatctctg gtcggcatgt ctccagagga aacccatact attttgaaaa
    25081 aagtccaaga gagtgatttt cgtggtctga ctgagctaaa tctttcctgt ccaaatgttc
    25141 caggtaaacc tcagattgcc tatgattttg agacaacaga ccggattttg gcagaagtgt
    25201 ttgcttactt caccaaacct cttggaatta aattgccacc ttattttgat attgttcact
    25261 ttgatcaagc ggcagctatt ttcaacaaat atccgctcaa gtttgtcaac tgcgttaact
    25321 ctatcggaaa cggcctctat atagaagacg aatctgtcgt tattcggcct aagaatggtt
    25381 ttggtggaat tggtggagaa tacatcaaac cgactgctct agccaatgtt cacgcctttt
    25441 atcaacgttt aaatcctcaa atccaaatta tcggaacagg tggcgttctg actggtcgag
    25501 atgcctttga acacatcctc tgtggagcaa gtatggtgca ggtgggaacg acccttcaca
    25561 aagaaggtgt cagtgctttt gaccgcatta ccaatgaact gaaagcaatc atggtggaaa
    25621 aaggctacga gagcttagaa gatttccgtg ggaaattgcg ctatattgac taaattaaat
    25681 cgaaaaatct gaagaaagga gagacgatgc tagccattga agaaagtcag aagttgactt
    25741 tatcaaattt accgagcctg agcctattta cagggacaga tcagggtcag tttgaagtga
    25801 tgaagagtca agtgttgaaa cagattgggt atgattctgc tgacctcaac tttgcctact
    25861 ttgatatgaa agaagtagtt tacaaggatg tggaactgga gttggtcagc cttcctttct
    25921 ttgcggatga gaaaatcgtg atattagatt attttatgga tatcacgact gctaagaaac
    25981 gctttttgac agatgatgag cttaagtcat ttgaggaata ccttgacaat ccttctccaa
    26041 caaccaagtt gataatcttt gcagaaggaa agctggatag caaaagacgg ttagtcaaat
    26101 tacttaagcg tgatgccaag gtcttcgatg cagtagaagt aaaagaacaa gaattgcgcc
    26161 agtatttcca aaagtggagt cagaaacaag gtctgcagtt taccaatcat tcttttgaaa
    26221 atctcctcat caagtcgggg tttcaattta gcgaaatcca gaaaaatctt ctctttttac
    26281 agtcctataa ggcggattct gttatcgagg aagaggatat tgttaacgca attcccaaga
    26341 ccttgcagga caatattttt gatttaactc agtttattct gactaaaaag atggatcagg
    26401 cgcgcgattt ggtgagagac ttgaccttgc aaggggaaga tgaaatcaaa ctgattgcag
    26461 tcatgctggg acaatttcgg acttttactc aggtgaagat tttggcggag tctggccaaa
    26521 cagaatcgca gattgcaagt agtttaggta gttatctggg acgtaaccca aatccttatc
    26581 aaatcaagtt tgcattaaga gattcgagag gactttcttt gagctttctg aagcaagcta
    26641 tttcctattt gattgagaca gactatcaga ttaagacagg tctttatgaa aaaggtttcc
    26701 tttttgaaaa ggcactctta cagattgcta gtcaggtcaa ttgacatttg ttgaaactac
    26761 aacccgcgtc aggattatct tgtcgtgggt ttcttgctga tttgcttatt ttattagaaa
    26821 gtatgtcagt gatttcctta tctataagca aaaaacttga aaaaagtgaa tgtttgcgtt
    26881 atcattttca tatagaaaga aaaagaggta ttacagatgg ctattatctt accagaactt
    26941 ccatatgcat acgacgcttt ggaaccatac atcgatgcgg aaacaatgca tttgcaccat
    27001 gacaaacacc atcaaactta tgtcaacaat gccaatgcag ctttagaaaa acaccctgaa
    27061 atcggtgaag accttgaagc cttgcttgct gatgtagaat ctatcccagc tgatatccgt
    27121 caagcactta tcaacaatgg tggcggacac ttgaaccacg ctcttttctg ggaattgatg
    27181 actcccgaga aaacagctcc ttcagcagaa ctggcagcag caatcgatgc aacatttggt
    27241 tcatttgaag aattccaagc agccttcact gcagcagcaa caactcgttt tggttcaggt
    27301 tgggcatggt tggttgtcaa caaagaaggg aaacttgaag tgacttcaac agcaaaccaa
    27361 gacacaccaa tctcagaagg taaaaaacca atcttgggct tggacgtttg ggaacatgct
    27421 tactacgtga aataccgcaa cgtgcgtcct gactacatca aagctttctt ttcagtaatc
    27481 aactggaata aagtagatga attgtacgca gctgctaaat aatgatagtt ggagggaaga
    27541 attgttcttc tcttttttag gttataagat tctggtctga caaaatcgtt agactttttt
    27601 cattttttat gagaaacgtg ctaactgcta gaaattatgg tagaataaag tattaagtaa
    27661 tcgtggaaaa aggatatcta tgcgaaaaga aattgcacct gaattataca actataacaa
    27721 gtttcctggt ccggagttcc atttacacgg ggacaaggtc gaaacggaag ggatagcttt
    27781 ttccttggtt gaaaatatca aggatgcctt tgatgtgacg acttttaatc agcgtttttc
    27841 agaagtctta accaagtttg attatatcgt gggggactgg agcaacgaac agcttcgcct
    27901 acgaggtttt tacaaggatg accgaacaga agaaaaactt gaaaaaatca gtcgtttaca
    27961 agactacctt ttagagtatt gtagttatgg ttgtgcctat tttgtcttag aaaatgaagc
    28021 ccctaagcga gcatcatttg acaagaaaat gcgtaagacg gaagaagaaa caccttctag
    28081 aaaaggaaag aaaccgactc aaactaaacg aaagtcgaat gcagataaga aaaatagacg
    28141 tcgtcagaaa gaccagcatt ctcagaaaga ggacaaggaa caacgtcatt ttgtcattcg
    28201 tcagaagtga gtagagaata aggagaagaa atgaaaccct caattcatag tttggtacat
    28261 caaaccatgc aggaatgggt attggagcag ggagaaaaga aattccgtgc agatcaaatc
    28321 tgggaatggc tctaccgtaa acgtgtgcag tcatttgaag aaatgaccaa cctttccaag
    28381 gatttgattg ctaagctcaa tgaccagttt gtggtcaatc ccttgaaaca acgtattgtg
    28441 caagagtctg ctgatggtac agtcaaatat ctctttgaat tgcctgacgg tatgttaatt
    28501 gagactgtac tcatgcgtca acactatggt ttatctgtct gtgtgaccac tcaggtcggc
    28561 tgtaatatcg gttgtacctt ctgcgcctct ggtttgatta agaagcaacg tgacctcaat
    28621 aacggtgaaa tcgtagcgca aatcatgctg gttcagaaat actttgatga gcgtggtcag
    28681 gatgaacgcg tcagccatat cgttgtcatg ggaatcggtg agccctttga taattacaac
    28741 aatgtcttga atttctttcg tactatcaat gatgataaag gaatggctat cggtgctcgt
    28801 cacatcacgg tttcaatctc aggtttggct cataaaattc gtgactttgc tgatgaaggg
    28861 gttcaggtca atcttgccgt gtctcttcac gcacccaaca atgaacttcg ttcaagtatc
    28921 atgaagatta accgtgcctt tccgattgaa aaactctttg ctgctattga atactacatt
    28981 gagacaacaa accgtcgtgt aacctttgaa tatatcatgc ttaatgaagt caacgacggt
    29041 gtagaacaag ccttggaatt ggctgaattg ctcaagaaca tcaagaaatt gtcttatgta
    29101 aacttgattc cttataaccc agttagtgag catgaccaat atagccgtag tcccaaagag
    29161 cgcgtgttgg ctttctatga tacgcttaag aaaaaagggg tcaactgtgt ggttcgtcaa
    29221 gagcatggta cagatattga cgcagcttgt ggacaattgc gctctaacac aatgaaacgt
    29281 gaccgccaga aggcagtcgc agcggtaaat ccttaatgat gaagaagact tataatcata
    29341 ttttggtctg gggagtcatt ttctatagca tttgcattgt ctgtttttgc tttactcctc
    29401 aagaacaatc taccgtggga gtgggaactc cagatattca gcatcttgga cgcctggttt
    29461 ttcttttgac tcctttcaat tctctctgga aactgggcga agtgagtgac attggacaat
    29521 tatgttggat ttttttacaa aatatcctca atgtcttctt gttttttcct ctgattttcc
    29581 aactccttta tctatttcca aatttgcgga aaacaaaaaa ggtccttctt tttagttttc
    29641 ttgtgagtct tggaatcgag tgtacgcaat taatcttgga ctttttcttt gatttcaatc
    29701 gcgtctttga gattgatgat ttgtggacca acactttggg tggctatctg gcttggctcc
    29761 tttataaacg attacataaa aacaagataa ggaattaaaa tgagtatttt agaagttaaa
    29821 aatctgagtc acggttttgg tgaccgtgca atttttgaag atgtgtcctt ccgtctcctc
    29881 aagggagaac atatcggcct ggtcggtgcc aatggtgaag gaaaatcaac ctttatgagt
    29941 atcgtgactg gtaaaatgct gccagatgaa ggaaaggttg agtggtccaa atatgtgacg
    30001 gctggttact tggatcagca ctctgtcctt gctgaaagac agtcggtgcg tgatgttctc
    30061 cgtacggctt ttgatgagct tttcaaagct gaagctcgta tcaatgacct ctatatgaaa
    30121 atggctgaag acggcgcgga tgttgatgct ctcatggaag aagtaggaga acttcaagac
    30181 cgtctggaga gtcgtgattt ctataccttg gatgctaaga ttgacgaagt agcgcgtgct
    30241 cttggtgtta tggactttgg catggatacg gatgtaactt ctttgtcagg tgggcaaaga
    30301 accaaggtgc ttttggcaaa acttctcctt gaaaagcctg atattttgct gttggacgag
    30361 ccgaccaact acttggatgc tgagcatatt gattggctca agcgctatct ccaaaactat
    30421 gagaatgcct ttgttcttat ttcgcacgat attccattcc tcaatgacgt tattaatatt
    30481 gtctatcatg tggaaaatca acagctgacg cgttactctg gtgactacta ccagttccaa
    30541 gaagtttatg ctatgaagaa atctcagcta gaggcagcct acgaacgcca gcagaaagag
    30601 attgcagacc tcaaggactt tgtggctcgt aataaagccc gtgttgcaac tcgtaatatg
    30661 gctatgtctc gtcaaaagaa attggataag atggatatta tcgaactcca aagtgagaaa
    30721 ccaaaaccat cctttgattt caaaccagct cgtacaccag ggcgctttat cttccaagcc
    30781 aagaacttgc aaattggtta cgaccgtcct cttactaagc ctttaaatct taccttcgaa
    30841 cgcaatcaaa aggttgcgat tattggtgct aatggtattg gaaaaacaac tctcttgaag
    30901 agtctcttag gcattatctc gccaatcgct ggggaagtgg agcgtggaga ttatttagaa
    30961 cttggttatt ttgagcagga agtagaaggc ggtaatcgcc aaactcctct tgaagctgtc
    31021 tggaatgcct ttcctgccct taatcaagca gaagtccgtg cagcccttgc ccgttgtggt
    31081 ttgacaacca aacatattga aagccagatt caagtattat cagggggaga gcaagccaag
    31141 gttcgtttct gtctcttgat gaatcgtgaa aacaacgttt tagtgctgga cgagccgacc
    31201 aaccatttgg atgtggatgc aaaggatgag ctcaaacgcg ctctcaaaga atacagggga
    31261 tctatcctta tggtctgcca cgagccagac ttttatgaag gttggataga ccaaatatgg
    31321 gattttaata atttaactta agaatgagag taaaagaaat acagtaccga atgtggatac
    31381 tgtatttttt tggtttttaa gatttaaaat cgtagtcttt caccacttcg atgctgtcga
    31441 ttgtgatagc agtagttggc ttgtcttttt catctttttc ggctttagca atcttatcca
    31501 caacatccat accgccaatc acttgaccaa agactgggtg tttgccatct agactagggt
    31561 ttccaccttc tttgtaggct tcgataattt tctgtggata cttgcttgta gggagtttag
    31621 aagaggtatc tgtagagttt tggttgatga agaactggct gccattggtg tttggttgac
    31681 cagtattagc catagcaaga gcaccgcgga tgttatacaa ataaggagta atctcgttct
    31741 tgaaaccagt tcctttgtct ttagtcttat ccttgtcatg ccagatggac tgaccacctg
    31801 taccgtcccc ttttggatct ccagtttgga ccataaagcc atcgatgaca cggtggaagg
    31861 taataccgtt atagtagcct tctttggcat gagtgaggaa attttcaacc gctagaggag
    31921 cgagtttagg gaagagttta atgcgaatat caccttggct tgtgtggaga atcacttcgg
    31981 cttcatcttc agcaacttcc ttagatagtt gtgggaaatt ggcgttttcg tttgttaatg
    32041 catcgtttaa ctccttggca gattgggcag ctactttgga actttcttca gcagcaagac
    32101 tggaatcaac ataatcatca ccacgcagac tgcgttggac gctgctacac ccagctaggg
    32161 ctacagtaga cagtaaaaga agggttgcta gttttttcat tctgatcctc tcaaaaattc
    32221 atttataacc attgtaccct aaaaggaagt ggatttcaaa tattagtagt ttacagaact
    32281 ggcttagata atagttggga tttcatcatc atcttgaaaa tcttcaactt cttcaacttc
    32341 ttccccagta aatggtttct gaaaagaact tagtataaaa cgggcaattg gttcaacaat
    32401 taggaaattt agaggaagag ctgcaataaa gtttacgaac caggcgctta gataggtatt
    32461 gggtgtgata gcaatgccat tgtaaaaaag tccatagaag gacatgaaag tgaccagcta
    32521 attcttcttc tgaaaaatgc tcatgaagag cttgatccag gttgcaagat ttcattttag
    32581 aaagtccagt aactcccttc ttcttcagga tattcttttt catggtagta tttagatggt
    32641 caagtgagtc aaaagaagtt tcgacaagag catacccttt ttctaccaga gtttttagat
    32701 gttttggggc atcaatgcca taagtgtact caaagtattt agggaaccag atcttaagaa
    32761 agctcgtaaa gctagccagt tctctaaacg ttaagaacta gctacaatac agcatttaca
    32821 acacttcatg gttcacacca tggggtgttt ttttatgatt ttaagcaaaa ttcacactta
    32881 attgaaagtt atttaaatta gatgaaaatt tattttttga aaaagtggga aaacattgat
    32941 tctaagcgaa ttttgaatca tattcgaatg ggagttttta aaatcatgtt tcagtggtaa
    33001 aagtaccaaa ctggattctc catagtaaaa tgatatctct tgctagtgaa tcatctgcta
    33061 ataagtccat atttcgcttg ggaacgggtt tggaacttag aagccaagta tccaactctc
    33121 gttcaggcga tatgaagggt ttgacttggt gttctttata aaatttttct aaaatagtat
    33181 tcacggatag catctttcaa acatttattt cctattctaa caaatttcta aatgctttaa
    33241 gaaatttata gtctgtcaag tttttttctt gacacctgcc agaaatctgc tataatagaa
    33301 catgtgctaa atagctcagc tatttcaccg aaataaaaaa ttaaagaaat gagactttaa
    33361 aaatggcagt taaaatccgt ttgactcgta tgggttctaa gaaaaaacct ttctaccgta
    33421 tcaacgtagc agattcacgt tcaccacgtg acggacgttt catcgaaaca gttggaactt
    33481 acaacccact tgttgctgaa aaccaagtaa ctttgaaaga agaccgcgtt cttgcatggt
    33541 tggctaatgg agctcaacct tcagacacag tacgtaacat cctttcaaaa gaaggcgtat
    33601 tgaaaaaatt ccacgattct aaattctcaa aataagttta aagtaggttg acagatggat
    33661 acgattgaaa atctcattat tgcgattgtg aaacccttaa tttcacaacc agatgcctta
    33721 actatcaaga ttgaggatac accagaattt ttggaatatc atttgaatct tgatcaaagc
    33781 gatgtgggtc gtgtaatcgg tcgtaagggt cgcactattt ctgcgataag aacgattgtc
    33841 tactctgtcc caactgaata caaaaaagta agaatcgtta ttgacgaaaa ataagaaggg
    33901 cgggacggat gtctcgcttt tttgtgtgga atagaagata tagtaaaatg aaataataac
    33961 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtaaaggtgt
    34021 actattctag tttcaatata ctataaaaga ttgaacgttt aggcaattcc aagactactt
    34081 actcgaacat taacagcagt ctcggactga tgaaggtctc tttatgaagt tagtggagga
    34141 agtcggagaa gtagccgagg ttttgaatag gcgctctggt cgaaaagaag ggataggatt
    34201 cgaacgagga acttgccaga gaactggctg atatcattta ctacaccgtc gcaatcgtag
    34261 ctattaatca tattgacctt accaagactg tctttgagaa agacaaaacc gcagccgtta
    34321 attaccaaca taaacataat ttggaaggat tattgaaggg aaagtagaga tgttgtcccc
    34381 ttcctccaac ttgagaaaat ccttggaacg tgataaaata aaggataagg atttttaata
    34441 attcattata tagaatgagt ggatttcttt atgaagaggt ttgaagtatc tacagaaatt
    34501 ggtagtctct ctgttgctta tcaaaagcaa aagaaagtgc tagtttgtct aaacggagca
    34561 ggtttgctac caagttatga aaatttttca cttatacttg aaaaacctcc tcctacaatt
    34621 ggttatttga caattgattt tccgaacaca ggtaggagtc cgattcatga ccaagctgga
    34681 aaaaatctag ataatcttgc agatgtggtt tatgaagcac ttgaagaatt agggatttct
    34741 gaatatatac tttgtgtaca tagttggagt ggaattttag cttgcaaatt actcgagaaa
    34801 ccaattaagt gtcagacttt agtagcaatt gaaccgacaa ctaaaaaagt catgtttgct
    34861 gatttttcag aaaatcctta tccagaaatg gaagagcaga tgaggctgat tgacgagtgt
    34921 ggtcctgaac tttattttaa gaacttaact caagcaacat ttagtcctga aacgaataaa
    34981 aaaatctggg aattaatgca agaaaaaggc ttagagttgg aaaatcaaga tccagaattt
    35041 cagatatctg gagagattac tgaggaagat tttgagaatt tgtcgataga atctcatgtc
    35101 cctgtattta ttttttgtca gacttataga gaaaaagagt acagagaatc agaatattgg
    35161 acttccaata ctaaactcat tttaggaggg aatcaccatt atttacaatg gtcagaatcg
    35221 gaaaaaattg cggctattat tcgagaattg tcagaataag atggaaaaaa ggagattaca
    35281 ggagacaaga tgaactactt taatgttggg aaaatcgtta atacgcaggg attacagggt
    35341 gagatgcgag tcttgtctgt gacggatttt gcagaagaac ggtttaaaaa aggagctgag
    35401 ctggctttgt ttgatgaaaa agatcagttt gtccaaacag tgaccatcgc tagccaccgt
    35461 aaacagaaga actttgacat tattaaattc aaagatatgt accatatcaa tactatcgaa
    35521 aagtacaagg gatacagtct caaggtcgct gaggaagatt tgaatgacct agacgatggt
    35581 gaattttact atcacgagat tatcggtttg gaagtctatg agggtgatag cttggttgga
    35641 accatcaagg aaatcctgca accaggtgct aatgatgtct gggtggtcaa acgaaaaggc
    35701 aaacgtgatt tgcttttacc ttatatccca ccagtggttc tcaatgttga tattccaaat
    35761 aaacgggtcg atgtggaaat cttagaaggg ttagacgatg aagattgata ttttaaccct
    35821 ctttccagag atgttttctc cactggagca ctcaatcgtt ggaaaggctc gagaaaaagg
    35881 gctcttggat atccagtatc ataattttcg agaaaatgct gaaaaggccc gtcatgtaga
    35941 tgatgagccc tacggaggcg gtcagggcat gttgctcaga gcacaaccta ttttcgattc
    36001 ctttgatgct attgaaaaga aaaatccgcg cgttattctc cttgatcctg ctggaaagca
    36061 gtttgatcag gcttatgctg aagatttggc tcaagaggaa gagctaatct ttatctgtgg
    36121 gcactatgag ggttatgatg agcgcattaa gaccttggta acagatgaga tttccctagg
    36181 tgactatgtc ctcactggtg gagaattggc agctatgacc atgattgatg ctacagttcg
    36241 cctgattcca gaagtgattg gcaaggagtc tagccaccaa gatgatagtt tttcttcagg
    36301 tcttttagaa tatcctcagt acacacgtcc ctatgattat cgaggcatgg tcgtgccaga
    36361 tgtattgatg agtggccatc atgaaaagat tcgtcagtgg cgattgtacg agagtttaaa
    36421 gaaaacctac gagcgcagac cggatttact tgaacattat caactgacag tagaagaaga
    36481 aaaaatgctg gcagaaatca aagaaaacaa agaataaagg agaaacctat gcaagtaatc
    36541 aaacgtaatg gcgaaattgc tgaatttaat ccagataaga tttaccaagc catcttgaag
    36601 gcagcccaaa ctgtttatgt tttgacagat gatttgcgtc aaaatcttgc tcaagtcact
    36661 aagaaggtag ttttggattt acaagaagcc aaggtggaac gtgcgactat cagtatgatt
    36721 caatctatgg ttgaacatcg tttattgggc gcaggttaca ttaccattgc agaacactat
    36781 atttcctatc gtttacaacg tgacttggaa agaagtggtt atggagatca tatcgcagtt
    36841 catttacatt ttgaacaaat tcgctaagaa aaagagtggg atgaagcaac tacatctcac
    36901 tctttcttaa atctattttt ttgggctgtt tggacagttg aggggacaaa tcgcaggcgt
    36961 tgaatatcgc ttatacggat aatccggctc acatttttgg aaaaattttt cacgataatt
    37021 tgctggcctt gctgatcata tttgatgatg tcacctgtaa agcttgtctc agataagata
    37081 aggtgaacag cggtttgttt ctggatagcc tcttcaatag tggctgtaag ggagttggtt
    37141 tcagtctggt caggttggtc atatccattt aaaaaatcat gtattttatt tagaacttgc
    37201 tggaatttat gtctcatatt ggcctccctt cttttatatc aatattatat aaaattttcc
    37261 taaaatctac aagattttac gaataaacta atgaaactaa aaaaggagaa gaaaatggca
    37321 gaatttacat ttgaaatcga agagcacttg ttgactcttt ctgaaaacga aaaaggttgg
    37381 accaaggaaa ttaaccgtgt gagctttaat ggtgcccctg caaagtttga tattcgtgct
    37441 tggagtccag accatactaa aatgggcaaa gggattactc tctcaaatga agaatttcaa
    37501 acgatggtgg atgcctttaa aggcaactaa tactcttcga aaatctcttc aaaccgcgtc
    37561 agctttgcct tgccgtatgt atggttactg acttcgtcag tttcatccac aacctcaaaa
    37621 cagtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    37681 aagttttcaa aataaaagaa aaggatattg agtcatgata actcgatatc cttttttagt
    37741 tagtaaagta agcctgattt ttaaggcgtt gaagtagggg acggctaata aaactaatag
    37801 ccagaagttt gccaaggtct ggaatgataa agggaagaac ccccacagca agagcttttt
    37861 caaatgccat tccagctagg aaatgcaagc tgagaatccc gccgacaaag acaagggcat
    37921 cacccaagag gtttgcaaga aaaatcttaa caacaccact cttgctgttg gttagagagg
    37981 aagtaagtcc agagtaaacg agataaaacc aaagatagcc tgcagtaggg ccaactaaag
    38041 cctgaaaacc agctccacct cctgcaaaga caggaagacc gatagcacct agaagaagat
    38101 agagtccagc agaaagtaca gcctctctcg gtctaaagac agtagcaatc aagccgattg
    38161 caaagttttg cagagtgaag ggaacaggtc caattggaag actgatttgt gccaaagcag
    38221 caatgagagc agccccaata gcagggatag cataaacgtg agcttttttc aaaatagtta
    38281 acctcttttc taatgtatag taactattat actcatatag gagtcgatgt caaccatttt
    38341 ttaaaaacaa ggtaacaaaa actgtaacag ccgattttcg tgactagtca agttggataa
    38401 tttttttgtt gattcgaaaa tcattaaaaa agaagcagac atatttatat cagcttcttt
    38461 tgtttcgatt aacgcatggt tacaaattct tcagatgaag ttgggtgaat cgctacagtt
    38521 gcgtcaaagt cagccttggt tgctcccatt ttgatagcaa cagcaaatcc ttgaatcatt
    38581 tcatcaacgc cgtagccaat tccgtgaagt ccgacaactt tttcttctga accagctgtt
    38641 atgagtttga aacgggattc ttgacggttg cgagtgcaag cagagtacat agatgcaaag
    38701 cttgatttgt aaaccttgat ttggtcttga ccgtattctt taatagcttg ctcttctgtc
    38761 aaaccaacag ttccgatagc agggtgtgaa aagacaacag ttggaatagt tgagtaatcc
    38821 atttttgcag tagtttttcc gttaaagaga cgttcagata gggtacgtcc ggccttgatt
    38881 gcaactggag tcagttcttt ctcgcccgtt acatcaccta gagcatagat tccctcaaca
    38941 acagtatttt ggtattcatc cacttggata aagccacgtt cgttcagagt cactccagct
    39001 ttttcaagtt gcaagccctt aacgtttgga cggcggcctg tagcccagat aacttggcta
    39061 gctgtgtgac tagtaccatc ttcgaaatga atggtaatgc cgtcagtagt tttttctaac
    39121 ttgacaggga ctttgtgagt gtgaagtggt aagtttgttc tttccatttc cttgaccaaa
    39181 ccttcaacga tgtaggaatc aaaaccacgt aaaggacgat cgcggcgaac aaagagatct
    39241 gtcttgacac caaaagtgtg gagtacgcca gctaattcaa cggcgatata accagcgcct
    39301 agaatggcaa ctgactctgg aagttcttcc caggcaaata catcatcaga agagccacct
    39361 agctcagcac caggaatatt aggaatactt ggatgggcac ctgtagcaat cacgatatgt
    39421 ttagcacgaa tcagttcacc atttacgctt acagtatgag aatctacaaa ttcagcatga
    39481 ccttcaatca agtctacacc gttgcgttta aaactgccat cataagaaga acgagcgcga
    39541 tcaatgtagg attcacgatt gcgacgtagg gttgcaaagt caaagttaag atcagtagtc
    39601 ttaaagccgt agtcttctcc aaattgatgg aaagtctcag cgatttgtgc cccgtaccac
    39661 atgatttttt taggaacaca accgacgttg acacaggttc cacctaattt cttttcctca
    39721 ataacggctg cttgggctcc atgttcacca gcacggttca tggtagcgat tcctccgcta
    39781 cctccaccga tagcaatgat atcatattct ctcattgaaa actcctttgt aatcttttaa
    39841 atagtagagc gtcttttttg atagttatat tttattcttt ttttgatttg attgcaaaaa
    39901 tctgctacgc acaaaaaatt gcaaaaaagc ttgccaaata agtcaagata gtgtattata
    39961 tatctagtac aatagaaaag caaaattccg aacgattgtt taatcctgaa ctgtattgtt
    40021 tgctggaggg aaatttggta taatagcaaa gtattgtaaa aaagaaaagg agtttcatta
    40081 tgaagaaaaa gaatggtaaa gctaaaaagt ggcaactgta tgcagcaatc ggtgctgcga
    40141 gtgtagttgt attgggtgct ggggggattt tactctttag acaaccttct cagactgctc
    40201 taaaagatga gcctactcat cttgttgttg ccaaggaagg aagcgtggcc tcctctgttt
    40261 tattgtcagg gacagtaaca gcaaaaaatg aacaatatgt ttattttgat gctagtaagg
    40321 gtgatttaga tgaaatcctt gtttctgtgg gcgataaggt cagcgaaggg caggctttag
    40381 tcaagtacag tagttcagaa gcgcaggcgg cctatgattc agctagtcga gcagtagcta
    40441 gggcagatcg tcatatcaat gaactcaatc aagcacgaaa tgaagccgct tcagctccgg
    40501 ctccacagtt accagcgcca gtaggaggag aagatgcaac ggtgcaaagc ccaactccag
    40561 tggctggaaa ttctgttgct tctattgacg ctcaattggg tgatgcccgt gatgcgcgtg
    40621 cagatgctgc ggcgcaatta agcaaggctc aaagtcaatt ggatgcaaca actgttctca
    40681 gtaccctaga gggaactgtg gtcgaagtca atagcaatgt ttctaaatct ccaacagggg
    40741 cgagtcaagt tatggttcat attgtcagca atgaaaattt acaagtcaag ggagaattgt
    40801 ctgagtacaa tctagccaac ctttctgtag gtcaagaagt aagctttact tctaaagtgt
    40861 atcctgataa aaaatggact gggaaattaa gctatatttc tgactatcct aaaaacaatg
    40921 gtgaagcagc tagtccagca gccgggaata atacaggttc taaataccct tatactattg
    40981 atgtgacagg cgaggttggt gatttgaaac aaggtttttc tgtcaacatt gaggttaaaa
    41041 gcaaaactaa ggctattctt gttcctgtta gcagtctagt aatggatgat agtaaaaatt
    41101 atgtctggat tgtggatgaa caacaaaagg ctaaaaaagt tgaggtttca ttgggaaatg
    41161 ctgacgcaga aaatcaagaa atcacttctg gtttgacaaa tggtgctaag gtcatcagta
    41221 atccaacatc ttccttggaa gaaggaaaag aggtgaaggc tgatgaagca actaattagt
    41281 ctaaaaaata tcttcagaag ctaccgtaat ggtgaccaag aactgcaggt tctcaaaaat
    41341 atcaatctag aagtgaatga gggtgaattt gtagccatca tgggaccatc tgggtctggt
    41401 aagtccactc tgatgaatac gattggcatg ttggatacac caaccagtgg agaatattat
    41461 cttgaaggtc aagaagtggc tgggcttggt gaaaaacaac tggctaaggt ccgtaaccaa
    41521 caaatcggtt ttgtctttca gcagttcttt cttctatcga agctcaatgc tctgcaaaat
    41581 gtagaattgc ccttgattta cgcaggagtt tcgtcttcaa aacgtcgcaa gttggctgag
    41641 gaatatttag acaaggttga attgacagaa cgtagtcacc atttaccttc agaattatct
    41701 ggtggtcaaa agcaacgtgt agccattgcg cgtgccttgg taaacaatcc ttctattatc
    41761 ctagcggatg aaccgacagg agccttggat accaaaacag gtaaccaaat tatgcaatta
    41821 ttggttgatt tgaataaaga aggaaaaacc attatcatgg taacgcatga gcctgagatt
    41881 gctgcctatg ccaaacgtca gattgtcatt cgggatgggg tcatttcgtc tgacagtgct
    41941 cagttaggaa aggaggaaaa ctaagatgca gaatctgaaa tttgcctttt catctatcat
    42001 ggctcacaag atgcgttctt tgcttactat gattgggatt attatcggtg tttcatcagt
    42061 tgttgtgatt atggctttgg gtgattccct atctcgtcaa gtcaataaag atatgactaa
    42121 atctcagaaa aatattagcg tctttttctc tcctaaaaaa agtaaagatg ggtcttttac
    42181 tcagaaacaa tcagctttta cggtttctgg aaaggaagag gaagttcctg ttgaaccgcc
    42241 aaaaccgcaa gaatcctggg tccaagaggc agctaaactg aagggagtgg atagttacta
    42301 tgtaaccaat tcaacgaatg ccatcttgac ctatcaagat aaaaaggttg agaatgctaa
    42361 tttgacaggt ggaaacagaa cttacatgga cgctgttaag aatgaaatta ttgcaggtcg
    42421 tagtctgaga gagcaagatt tcaaagagtt tgcaagtgtc attttgctag atgaggaatt
    42481 gtccattagt ttatttgaat ctcctcaaga ggctattaac aaggttgtag aagtcaatgg
    42541 atttagttac cgggtcattg gggtttatac tagtccggag gctaaaaggt caaaaatata
    42601 tgagtttggt ggcttgccta ttactaccaa tatctctctt gctgcgaatt ttaatataga
    42661 tgaaatagct agtattgtct ttcgagtgaa tgataccagt ttaaccccaa ctctgggtcc
    42721 agaactggca cgaaaaatga cagagcttgc aggcttacaa cagggagaat accaggtggc
    42781 agatgagtcc gttgtatttg cagaaattca acaatcgttt agttttatga cgacgattat
    42841 tagttccatc gcagggattt ctctctttgt tggaggaact ggtgtcatga acatcatgct
    42901 ggtttcggtg acagagcgca ctcgtgagat tggtcttcgt aaggctttgg gcgcaacacg
    42961 tgccaatatt ttaattcagt ttttgattga atccatgatt ttgaccttgt taggtggctt
    43021 aattggcttg acaattgcaa gtggtttaac tgccttagca ggtttgttac tgcaaggttt
    43081 aatagaaggt atagaagttg gagtatcaat cccagttgcc ctatttagtc ttgcagtttc
    43141 ggctagtgtt ggtatgattt ttggagtctt gccagccaac aaggcatcga aacttgatcc
    43201 aattgaagcc cttcgttatg aatgagatca acaagatgga cactcgtcta tcttgttttt
    43261 gtatggattt ccctatcgaa attcattaaa aatgtgatat aatgaagtgt tagaaaaaca
    43321 ggtttcattt gcctggaaag gaaaaattat gtctgaaaaa aatttttata ttacaacgcc
    43381 gatttactat ccatctggga aacttcatat cggttctgcc tacacaacta tcgcatgtga
    43441 tgtcctagca cgttacaaac gcctgatggg ctacgatgta ttttatctga caggtcttga
    43501 tgaacatggt cagaaaatcc agcagaaagc ggaagaagct ggtattacac ctcaagccta
    43561 tgttgatgga atggcggttg gagttaaaga actctggcaa ttactagata tctcatacga
    43621 taaatttatc cgtacaactg atgactacca tgaaaaagtt gtcgcacaag tctttgaacg
    43681 cttacttgct caagatgata tctacttggg tgaatactct ggttggtatt cagtatcaga
    43741 cgaagaattc tttacagaaa gccagctggc agaagttttc cgtgatgaag ctggaaatgt
    43801 gactggtggt attgctccat caggtcatga ggttgaatgg gtttctgaag aatcatactt
    43861 ccttcgcctt agcaaatacc aagaccgttt ggtcgaattt ttcaaagctc atcctgaatt
    43921 tatcacgcca gatggtcgcc ttaatgaaat gctacgcaac ttcatcgagc caggcttgga
    43981 agatttggcg gtatctcgta caacctttac atggggagtg cctgtcccat caaatccaaa
    44041 acacgttgtc tacgtttgga ttgatgccct tcttaactat gcgacagctc ttggctacgc
    44101 tcaagacgaa catggtaact ttgacaagtt ctggaatgga acagtcttcc atatggtagg
    44161 aaaagatatc cttcgcttcc actctatcta ctggccaatc cttcttatga tgttggatgt
    44221 taaattacct gatcgtttga ttgcccatgg ttggtttgtc atgaaagacg gaaaaatgtc
    44281 taagtcaaaa gggaatgtcg tttaccctga aatgttggta gagcgttatg gactagatcc
    44341 acttcgttac tacctcatgc gtaaccttcc agttggttca gacggaacct ttactcctga
    44401 agactatgtc ggccgtatca actatgaatt ggctaatgac cttgggaacc tccttaaccg
    44461 tacggtttcc atgattaata agtactttga tggacaaatc cctgcctatg tagaaggtgt
    44521 gactgaattt gatcatgttc ttgctgaggt tgcagaacaa tcaatcgcag acttccatac
    44581 acacatggaa gcagttgact atccacgtgc gcttgaagca gtctggactc tgatctctcg
    44641 taccaataaa tacatcgatg agaccgcacc atgggtcttg gccaaggatg aagctcttcg
    44701 tgaccaattg gcaagtgtca tgagccactt ggcagccagc attcgtgtag ttgctcactt
    44761 gattgaacca tttatgatgg aaactagtcg tgcagttttg actcaacttg gtttggaaga
    44821 agtttctagt cttgaaaact tgagtttggc tgacttccca gcagatgtga ctgtagttgc
    44881 caaaggaaca cctatctttc cacgtctaaa tatggaagaa gaaatcgcct atatcaagga
    44941 acaaatggaa ggcaataaac cagcagtcga aaaagaatgg aatccggacg aagttgagct
    45001 caaactaaac aaggatgaaa tcaagtttga agactttgac aaggttgaaa tccgtgtcgc
    45061 agaagtcaaa gaagtgtcta aagtagaagg ttcagataag ttgcttcaat tccgcttgga
    45121 tgctggtgat ggagaagatc gtcagattct ttcaggaatt gcaaaatact atccaaatga
    45181 acaagaattg gtcggcaaga aagttcaaat cgttgctaac ctcaaaccac gtaaaatgat
    45241 gaaaaaatat gtcagccagg gtatgattct ctcagctgaa catgatggca aattaaccct
    45301 tctcacagtt gatccagctg taccaaatgg aagtgtgatt gggtaaaagt agacaggact
    45361 agttcaggct agttctgttt ttttatttat actcaatgaa aatcaaagag caaactagga
    45421 agctagccgc aggt
//
LOCUS       DBEJJE010000013        43023 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEJJE010000013 DBEJJE010000000
VERSION     DBEJJE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.13"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(59..538)
                     /locus_tag="ACL3F5_000711"
     CDS             complement(59..538)
                     /locus_tag="ACL3F5_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0514555.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(660..2618)
                     /gene="ftsH"
                     /locus_tag="ACL3F5_000712"
     CDS             complement(660..2618)
                     /gene="ftsH"
                     /locus_tag="ACL3F5_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0514556.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2634..3176)
                     /gene="hpt"
                     /locus_tag="ACL3F5_000713"
     CDS             complement(2634..3176)
                     /gene="hpt"
                     /locus_tag="ACL3F5_000713"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0514557.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(3180..4457)
                     /gene="tilS"
                     /locus_tag="ACL3F5_000714"
     CDS             complement(3180..4457)
                     /gene="tilS"
                     /locus_tag="ACL3F5_000714"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0514558.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRTKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4454..5722)
                     /locus_tag="ACL3F5_000715"
     CDS             complement(4454..5722)
                     /locus_tag="ACL3F5_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0514559.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5715..5837)
                     /locus_tag="ACL3F5_000716"
     CDS             complement(5715..5837)
                     /locus_tag="ACL3F5_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0514560.1"
                     /translation="MENLLDVIEQFLGLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5842..6210)
                     /locus_tag="ACL3F5_000717"
     CDS             complement(5842..6210)
                     /locus_tag="ACL3F5_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0514561.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(6203..6469)
                     /locus_tag="ACL3F5_000718"
     CDS             complement(6203..6469)
                     /locus_tag="ACL3F5_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0514562.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6527..10036)
                     /gene="mfd"
                     /locus_tag="ACL3F5_000719"
     CDS             complement(6527..10036)
                     /gene="mfd"
                     /locus_tag="ACL3F5_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0514563.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(10037..10606)
                     /gene="pth"
                     /locus_tag="ACL3F5_000720"
     CDS             complement(10037..10606)
                     /gene="pth"
                     /locus_tag="ACL3F5_000720"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0514564.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10677..11792)
                     /gene="ychF"
                     /locus_tag="ACL3F5_000721"
     CDS             complement(10677..11792)
                     /gene="ychF"
                     /locus_tag="ACL3F5_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0514565.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11876..12070)
                     /locus_tag="ACL3F5_000722"
     CDS             complement(11876..12070)
                     /locus_tag="ACL3F5_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0514566.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(12135..13271)
                     /gene="dnaN"
                     /locus_tag="ACL3F5_000723"
     CDS             complement(12135..13271)
                     /gene="dnaN"
                     /locus_tag="ACL3F5_000723"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0514567.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(13430..14791)
                     /gene="dnaA"
                     /locus_tag="ACL3F5_000724"
     CDS             complement(13430..14791)
                     /gene="dnaA"
                     /locus_tag="ACL3F5_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0514568.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(15004..15762)
                     /locus_tag="ACL3F5_000725"
     CDS             complement(15004..15762)
                     /locus_tag="ACL3F5_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0514569.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15820..17001)
                     /locus_tag="ACL3F5_000726"
     CDS             complement(15820..17001)
                     /locus_tag="ACL3F5_000726"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR0514570.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            17184..17663
                     /gene="rlmH"
                     /locus_tag="ACL3F5_000727"
     CDS             17184..17663
                     /gene="rlmH"
                     /locus_tag="ACL3F5_000727"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0514571.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17707..17780
                     /locus_tag="ACL3F5_000728"
     tRNA            17707..17780
                     /locus_tag="ACL3F5_000728"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17741..17743,aa:Arg,seq:tct)
     gene            17981..18070
                     /gene="comC"
                     /locus_tag="ACL3F5_000729"
     CDS             17981..18070
                     /gene="comC"
                     /locus_tag="ACL3F5_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0514572.1"
                     /translation="MKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            18091..19416
                     /gene="comD"
                     /locus_tag="ACL3F5_000730"
     CDS             18091..19416
                     /gene="comD"
                     /locus_tag="ACL3F5_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0514573.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            19413..20165
                     /gene="comE"
                     /locus_tag="ACL3F5_000731"
     CDS             19413..20165
                     /gene="comE"
                     /locus_tag="ACL3F5_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0514574.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            20217..20288
                     /locus_tag="ACL3F5_000732"
     tRNA            20217..20288
                     /locus_tag="ACL3F5_000732"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20250..20252,aa:Glu,seq:ttc)
     gene            20294..20367
                     /locus_tag="ACL3F5_000733"
     tRNA            20294..20367
                     /locus_tag="ACL3F5_000733"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20328..20330,aa:Asn,seq:gtt)
     gene            complement(20408..20950)
                     /locus_tag="ACL3F5_000734"
     CDS             complement(20408..20950)
                     /locus_tag="ACL3F5_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0514575.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            21078..22731
                     /locus_tag="ACL3F5_000735"
                     /pseudo
     CDS             21078..22731
                     /locus_tag="ACL3F5_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22761..25313)
                     /locus_tag="ACL3F5_000736"
     CDS             complement(22761..25313)
                     /locus_tag="ACL3F5_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0514576.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     GAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFMTGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(25375..26997)
                     /locus_tag="ACL3F5_000737"
     CDS             complement(25375..26997)
                     /locus_tag="ACL3F5_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0514577.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            27203..28228
                     /gene="trpS"
                     /locus_tag="ACL3F5_000738"
     CDS             27203..28228
                     /gene="trpS"
                     /locus_tag="ACL3F5_000738"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0514578.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            28380..29858
                     /gene="guaB"
                     /locus_tag="ACL3F5_000739"
     CDS             28380..29858
                     /gene="guaB"
                     /locus_tag="ACL3F5_000739"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0514579.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29909..31006)
                     /gene="recF"
                     /locus_tag="ACL3F5_000740"
     CDS             complement(29909..31006)
                     /gene="recF"
                     /locus_tag="ACL3F5_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0514580.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKVAVNGN"
     gene            complement(31009..31377)
                     /gene="yaaA"
                     /locus_tag="ACL3F5_000741"
     CDS             complement(31009..31377)
                     /gene="yaaA"
                     /locus_tag="ACL3F5_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0514581.1"
                     /translation="MEYKLFEEFITLQALFKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31536..32786
                     /locus_tag="ACL3F5_000742"
     CDS             31536..32786
                     /locus_tag="ACL3F5_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0514582.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQSYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32783..34066
                     /locus_tag="ACL3F5_000743"
     CDS             32783..34066
                     /locus_tag="ACL3F5_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0514583.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            34108..34929
                     /gene="rodZ"
                     /locus_tag="ACL3F5_000744"
     CDS             34108..34929
                     /gene="rodZ"
                     /locus_tag="ACL3F5_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0514584.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34940..35485
                     /gene="pgsA"
                     /locus_tag="ACL3F5_000745"
     CDS             34940..35485
                     /gene="pgsA"
                     /locus_tag="ACL3F5_000745"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0514585.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35482..36309
                     /locus_tag="ACL3F5_000746"
     CDS             35482..36309
                     /locus_tag="ACL3F5_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0514586.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            36294..37133
                     /locus_tag="ACL3F5_000747"
     CDS             36294..37133
                     /locus_tag="ACL3F5_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0514587.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEKVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            37126..37920
                     /locus_tag="ACL3F5_000748"
     CDS             37126..37920
                     /locus_tag="ACL3F5_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0514588.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37979..38797
                     /gene="mreC"
                     /locus_tag="ACL3F5_000749"
     CDS             37979..38797
                     /gene="mreC"
                     /locus_tag="ACL3F5_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0514589.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38797..39291
                     /gene="mreD"
                     /locus_tag="ACL3F5_000750"
     CDS             38797..39291
                     /gene="mreD"
                     /locus_tag="ACL3F5_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0514590.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFAIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            39385..40563
                     /gene="pcsB"
                     /locus_tag="ACL3F5_000751"
     CDS             39385..40563
                     /gene="pcsB"
                     /locus_tag="ACL3F5_000751"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0514591.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40787..41566
                     /gene="rpsB"
                     /locus_tag="ACL3F5_000752"
     CDS             40787..41566
                     /gene="rpsB"
                     /locus_tag="ACL3F5_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0514592.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41645..42685
                     /gene="tsf"
                     /locus_tag="ACL3F5_000753"
     CDS             41645..42685
                     /gene="tsf"
                     /locus_tag="ACL3F5_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0514593.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT        13460 a         7454 c         7895 g        14214 t
ORIGIN      
        1 cttttcaaac tttgtcaact actttttcta atttttttca ttttttttgc atgacttact
       61 aatgggtacg gatagtaaac tccttaaaca caatgcgtaa gtctcttaat actctttgac
      121 gccctcgaaa tcgttcattg cttaagacgc gttctagttc ttcttgtttc tctttacttt
      181 gtttgtttct ataatctctt agtgtttcat gaaagagata ataatcatct agccagagac
      241 ccccctcact tatacgatga ctgatctcac ccacttcttc atagggttct ttatcgtatc
      301 tacgcttctg actttcctgc ttacggatat agtctaaaat tcgatttcga aacttggttt
      361 tgaaatattt ccttaaacgt ggaatatcgt ctaccagtcc ttcttctcta ctaatcaatt
      421 catgtaagca gagcatgcct tcttggtccc aatccgacaa ttcccataaa tgaaggtaat
      481 attcatttct acacttatac acagtccctt ggacttcttc atacaattct ttaatcataa
      541 ttttcccctt tctagataca gtctaacaga ttagaaaaca catttgttcc attttctcca
      601 ttctgttccc tttagctcct aaactgcaca aaaaagagag gctccagcct ctctcagggt
      661 tatttttcgt cattcatttt tgactttact tcatcatagg atagtgcatg agattcctct
      721 tctactgctt caggcatctt tcctgtttcg taaagagctt taatttgtgt actatccaat
      781 gtttcgtatt tcaataatgc ttctgcaatt aacttgtgag tttcacgatt tgactgaata
      841 atttcagcag ctttatttcg tgcctcattt aataatgaac gaacctcttc atcaatttca
      901 taagctgttt gttctgaaat tgatttttga ggactctgtg caccaagcat agcatggttt
      961 ccttcatatt gtactgggcc aagtttttca ctcataccgt actctgtaac cattgcacgt
     1021 gccatttgtg tcgcttgttc aaagtcgttt gaagctcctg tagtttggac attaaagata
     1081 atttcttcag ctacacgtcc acccattaag ccagccaatt gctctttcat atcttcttta
     1141 gatagaagca tttgatcctc tttaggaagt gcaatcatgt atccgcctgc acggccgcgt
     1201 ggtacaattg taaccttatg gacaacgcga gcattcgaca agactagacc aacaatggta
     1261 tgtcctgcct catggtaagc aaccaattct cgttcttttt gtgaaactgt cttatctttc
     1321 ttagaaggtc cagcaataac tctatcttct gcttcatcaa tatctgaagc atcaattatc
     1381 gatttattgc gacgagcagc aactaaagct gcttcattca agacattctc taaatcagca
     1441 ccaacaaagc ctggagtttg ttgagccact aatttcaaat caacatcttc tgctaaaggc
     1501 ttgttcttag cgtgaacttt caagattgct tcacgacctt taacatcagg acggccaacc
     1561 aatacttttc tatcaaaacg tcctggacgc aaaagggcag gatcaagtac atctgaacgg
     1621 tttgtcgcag cgatgacgat aatcccttca tttccctcaa aaccatccat ctcaatcaaa
     1681 agttggttca aggtttgttc acgttcgtca ttacctccgc cgagaccgac tccacgttga
     1741 cgtccaacag catcaatttc atcgataaag atgatagctg gtgctgcttt tttggcatcc
     1801 tcaaaaagag agcgaacacg actagctcca actccgacaa acatttctac aaagtcagaa
     1861 cctgagatac taaagaatgg aacacctgct tctccagcga ctgccttagc aagcaaagtc
     1921 ttacctgtcc ccggaggtcc ctccaaaaga acacctgctg gaatacgggc tccaagtttt
     1981 gtgaatcgtt ttggatcttt taagaactca acaacttcaa ctagttcttg tttttcttcc
     2041 tcagctccag caacatctga aaatcttact ttaatatctt ctttatttgc tgctttagcc
     2101 ttactacgtc caaaactcat tggattacgg ccattgcctc ctcccatatt tcccatcata
     2161 gagaatagga agaagaatag aattccaaat ggcacaatgg atacgagtag attaatccat
     2221 ataccacttg aactttcatg cttaacagtt acttctgctt tatggtcagt agcaagtttt
     2281 tgcaattctg atacggtagt atctgcagga agaatagtgc tggtaaattt ctctacctta
     2341 gtaacagatg gcgtgaaaaa ctgaatacct gttccttctt tacttgtttt aggattttta
     2401 tagacaccag aaacttcgat aacactacca tttggttggt aagttaattc ttttacatta
     2461 ccatcggtaa tttcttgtac caactcagta tagttgattt gctgacttcc tcctgagtta
     2521 ttcccagaat agaaatactg gaatcctgtc acaaggaaaa agataaataa taaccataga
     2581 aaaggatttt taattaaacc attattttgt tttttcatta aagattattc tttctaattt
     2641 gaatacactt cctctttcaa tactccaata taaggaagat tacgataatt ttctttgtag
     2701 tctaaaccat aacctactac aaactcattt gggatagtaa agcaggtata gtctgcctca
     2761 atttctacaa cacgtccttc tggtttatcc aacaaggttg caattttaac agaagctgct
     2821 tctctttctt taaacatatc tcgcaaattc ttcaaagttt gacctgtatc aatgatatct
     2881 tctacaaata gaacatgtct tcctttgata tcttgagtca catcttgttt aatattgata
     2941 acaccactac ttgctgttcc accatggtag ctagaaacca tcatgaagtc catttcaata
     3001 tgtgtatcaa tatgtttgac caattcagcc ataaaaggaa tagatccttt taaaatccca
     3061 actaagattg gattttttcc tgcataatct ttagttaatt gagcacctag ttttttagct
     3121 gcttctgtaa tttcatcgtg tgaaacgagg acttttttaa tatcgttttc taacattttt
     3181 tacctatcta ttttttctat ataaagtaca gtgttcatta tatcattttt cgttttttta
     3241 ctcaaattat tggtcgcaat tcccaaaatt gagacaattt caccaaattg ctcaataata
     3301 agagcagagt ttctcttttc catagggatt ttcaaatcaa taaataaacg tctgagtttt
     3361 gttctatgcc cattttgaat caaaacatct cctgtttttc gatgacgaat gtgtatggat
     3421 gtttcacgtg aaacaggtat ttgttgaatt gattcacctt ctaatggaag tccaaaggaa
     3481 aataaatatc cttgataagc tacctgattt tgatagtgta acacaagttc atcttccttt
     3541 tcatcagcct gcggactgat tttacaaatc tgaaactgtt ggtactcttt tatcaattca
     3601 tagccatttt taatcggatg acgatactgg cttttagatt ttaaaatctg ctgaacttca
     3661 gcaaactgag cttttgtaag attcaaatct ggaaaacgat tcagataagt ttgaagtaaa
     3721 actctttgtg tagactcaga gtaagaaaat aactgctgta aatcttccac attaatattg
     3781 ttagataatt cagctattgc caaatcataa tctaaaattt cattgccaat gcctaagatt
     3841 gcatccctaa atcgaggatt ttctttttcc aattctggta agtaagagtt tcgaatacga
     3901 tttcgaaaat aatgattctc ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag
     3961 tcttttttct gaaaatgcaa gaagggacga atgatttcta tctctccgac tacttgcttc
     4021 tccttaattc ctgatagata gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt
     4081 tccacctgat catcagcatg gtgggcagtg actaaagctg tcgcacctgt ctttttcata
     4141 acctcttgaa aaaaatcata acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa
     4201 aaattgctga tataaatagg aagctctgct tcagcagcca acttccttaa ttccttttct
     4261 tcccaatctg attcaattct ctgcttatga ttcacatgag ccagaatcaa ttcaatctct
     4321 aactcttttt gataagtaga caatacctta aatagaaaca tagaatctaa tccaccagaa
     4381 agagctagaa ccgccttagc atgctttttg aaatatccct tcttgagaaa atgatttaaa
     4441 aaatctggtt ccctcatttt aaaacctcat aaacatcctt ggctatctta gaaatcgtat
     4501 cataatcaga attcttagtg aaaatagaaa gaataaatgg agaatctgca tagacaacac
     4561 ccgtatcatg cttaaattca tccgcatctc caattttatg agctacttta acagaaacac
     4621 ctttggcaat tcgctgacta tcaaaatctg ttttagtcaa agactctagc acaaatccat
     4681 tttgattata aatagcttcc ataaacttcc cggccatctt agaagaaatc aatttttctt
     4741 ttggatccca atcatctccc ataatggcag acattttgga tttgaatgtg gcatcagatt
     4801 ggtttgaaat gtaatatccc aatagattat gagctacatt atcagattct tttgatactt
     4861 tcgtaattaa atcctttaaa gaatattctt tattatcttc ttttttagga agactaccac
     4921 ttccctctgg tttataagaa cctggaaaat cattgactgc agatacgtat tttacagtcg
     4981 tatctaactg ataaagaccc tcatttattt tttcttgcgt ataatagaga taggagagtt
     5041 tcaaaacgct ggctgcatac atcttttcat cttgattgat accagcttct tttccagtag
     5101 tcagttgctt aacataaata gagaaagaat ctttctgata tttttcagat aacatttctt
     5161 gaactttact catccgatta tcttcttcag aagttgattc tttagctacc catccagcct
     5221 gatcaatatg tagaaattct cttccttcta caaacatggt cttgtcgatt gatacttgcg
     5281 aataagctga taaggatgat ttcacttctt ttaaatcata aggactattg tacagtttaa
     5341 agtcagattc taaccatact ttttttattg ttggagttac ctctgattga tcatataaaa
     5401 atcgtttgtc cgcagctata aattgatgat ttgatagctt aaatactgga atcccttgtt
     5461 tatttaagcg ccactcggtt atttgaaaac ttgttttggg agtcaattcc ccagattcca
     5521 ctactaaatc ttcattcgca taaacaggaa cctctccata aaccatggga gaacttaatt
     5581 tttctctaaa ataaatacca aagtcagatt gtgaaaggta ataaatttct ttcgaagtat
     5641 agacgacttc tttttctgtg ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca
     5701 aaataattaa gaatttacgc attcttcctt tccttttctt cttgtaaacg caataattga
     5761 tttttatcag ccaattcttc caacttttca tctgacaaac ccaaaaattg ctctattacg
     5821 tctaataaat tttccatttt atcacctttg aagcaagtca ggaatcgtat aaactttttc
     5881 cctcgactta gaataatagt acttcgctcg tgtatattta gcagcataat cttcatcttt
     5941 caacttggta gcaaatgctg tctccttatc cttttcatca ctcaaagttt gatactgagt
     6001 ttgcaagtct gctaattgct gacgtctttg gagtaattgc tgataactct gcgctaaatt
     6061 aaaagttggc aagataaata atagcataat caaaatcaat acccctccca taaaacgatt
     6121 ccgtttttgt cgttctttca tcaggtagcg acgacgttgg tattcatttt gaataaaaga
     6181 attattcaat tgtacaatat ttttagacat tttcttctac ccgtgtttca ctgataattt
     6241 catacattcc tgctgcatct tctttttttg tactatcttt catctctagt acttttacaa
     6301 gcagcaactt attgccaaag cgaatttcaa cttggtcatt aactttcaag tccgttgaac
     6361 ttttggccaa gattccatta accttgattc tacctttatc tgctacttcc tttgcgactg
     6421 tacgacgctt gataattcgc gatactttta aatatttatc taatctcatc cttattacct
     6481 caatttatta ttgtaccatt tttatctatt ttatagaaga aaaatatcaa atggaatttt
     6541 cttccttaga ctcttttatc tctaataaac tttctccaaa aatcagcaga ccttctaaaa
     6601 tttcataatc tttcttattt tgaacatcaa atacaagctc cattaattcc ttattctcag
     6661 cgatgcctgc ttttaagttc gttacggata aagctttaaa ataatcttga gctaaaaaca
     6721 gtcgttgagt gactttttca aattgaattg taattttatt atcttttctt tccacacgtt
     6781 gaacaaagac cttgtccaag tatgatttga ccaaaccaat ctctaaaaga taggctacta
     6841 catctgggta ttctccaaaa cggtctatca actcctcttg taactcttca taattgacac
     6901 ggttgtcaat ttgacgaatt ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat
     6961 aagtatcagg aagataggca tcaatttgca aaatcaactc agcattccct ttggttcttg
     7021 tgttagcgtt agcattaccg tttcgtttag caatagcttc ctctaataac tgcgaataca
     7081 attcaaaacc aacagaatca atgaaaccag actgggattt tcctaaaaga tttcctgctc
     7141 cacgaatcga aagatctcgc attgcaatct taaagccaga gcccaattct gtaaatcctt
     7201 taatcgcttc taatctcttt tcagagactt cactgattga tttttctgga cgatacatga
     7261 gataagcata agcaatacga ttactacgac cgactcttcc tcttaactga tataaggttg
     7321 acaagcccat atggtccgca ttttcaataa ataaagtatt agcatttgga atgtccaccc
     7381 ctgtctcaat aatagtagtc gtcaccaaga tatcgtattg tccctcaata aagtctaata
     7441 gagtattttc caactggact tcactcattc gaccatgaac atatccaatc gaagcctccg
     7501 gaatcaactc ctgtaattct gaaaccttct gaacaattgt gtcaactttg ttgtaaagat
     7561 aataaacttg acctccacgc tccatttcac gcaagacagc atcacgaatg acactatcat
     7621 tcttttccaa aacataggtc tgaacaggat agcgattagt cggcggagtt tcaataacag
     7681 ataaatctct gattcccagc atagacatat ggagggtacg agggattggc gtagcggtca
     7741 aggttaggac atccacttgt ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa
     7801 atcgctgttc ctcatcaata atcatcaagc ccaaatcagc aaacacaaca tcttttgaca
     7861 aaacacgatg tgttccaatc aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg
     7921 cagtctgctc ttttttactt ctaaagcgac tcaacacatc aatattaact gcaaaatttt
     7981 ggaatcgttc cttaaaattc gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa
     8041 tgacaacctg tttgtgatca ttgactgctt taaaggctgc acgcatagca acttcagtct
     8101 ttccaaaacc aacatcccca actaaaagtc gatccattgg ctgagaagcc tgcatatccc
     8161 tcttgatttc ctcaatacta cgaagttgat catccgtttc aacataaggg aaagcatcat
     8221 caaaggcatc ttgatcatca tcatcagctg agaaagcaaa acccttcaac tgactacgtt
     8281 cagagtagag tttgattaaa tcatcagcta tatcctctac ctggttctta accttttgct
     8341 tggccttttt aaaatgaccg tcatttaatt tattgagttt tggagcttta ccatcacttg
     8401 aaatatattt ggacagtaga tgaatctgtt ccacgggaat agaaatttga tcaccatttt
     8461 ggtattggac actgacataa tcacgatgaa ttcccttgat ttcaatggtt tcaattccta
     8521 gatattgacc aatcccatgg atatgatgga caacatagtc ccctttttca agttcattgt
     8581 aatcttttaa tctctctgca tttgaaacat gttgtcttcg aaaacgacgc tttaatttct
     8641 tttgaaaaat ctcatgttca gttatcaata aaatcttttc atctacaaaa tgaaaaccat
     8701 gtctgagatt accctctatt aagtttacag attctttaca gatatttgtc ttatctctag
     8761 aatccaattt aatctgatat tcctctaaca tatcctccaa tgttttactt cccattgaat
     8821 tgctagactg cagaataatg gtgtaatcca tttttttata tcgttcaatt tcttctttta
     8881 gaaaagaaaa ctgattgaaa aattcctgca taggatattg attgaattga taaattttgt
     8941 caaatttgag atttcctaaa cccttttgaa gattagaaaa aaaggtcact ggactttgtt
     9001 ttttatagat ttgttcaata tcagaaaaat actgcatatc agaaaatgct ttactattct
     9061 gtaattcttc tgtaaagtac tgcgctaatt ctctttcaaa gacttcatac tgattcatca
     9121 atttttgata atcatcaaag aatattggag tatctttttc aatataatca aagacagtcc
     9181 atgtcttatc atagcacaaa gataaaaact tccgagagtc tgcatgactt tgtttttggt
     9241 gaaaacttga aagaatttct tctaggtatg atttcaaaat aggtgataaa gtttttgaaa
     9301 tttgtttttc taaagctgac tgtcctcgtt gataatcctt ttctctcaaa agcatatcac
     9361 tagctggaaa gatagtgagt tctgtcttat tttctttcga taattgtgtt tctacttcaa
     9421 atgacctgat accatcaatt tcatcaccaa aaaactcaat tcgacaaggt tctaactggg
     9481 atatttcaaa aatatctaaa atatctcctc gaagactaaa ttcgccctga gtttgtactt
     9541 gagtaacttt tcgatagcca ttttccttta actgatggat aaacgcgtgt tgatcatatt
     9601 cttcaccaac tgagattttt acaatactat ctttgaatgc attgggagac ggtaaaatca
     9661 atcgacttgc tgcgatatta caaactaaaa tccctttctt agatgaatca gtcaaaaaac
     9721 gcaaggcttc aacccgtgaa ataatttttt cctgtgaaga catcaaaaac tccaccatag
     9781 gagcatcatc taccaaaaat ggatagacga gttcctcacc caagatagat ataagatcac
     9841 taacaagtcc ttctgcttct ccataagttg acatcaataa cacaatccta tcttcttttt
     9901 ctaaactgct tgcaattgca agagccttag tagatgttga taaaccaagt attagttgtc
     9961 ttttcttatc tgttaaattt tgatgccatt ttttaatctg atcattttct gagaataaat
    10021 ctaataaggt caccatttat ccgttatacc tctgcattgt tttctcaaaa tttttctctt
    10081 gtaaatagta gtttacagaa tcgtcaactt tgtcaacaga ctgtaaaata ccgatatact
    10141 catccctgtc aaacttactc aaaacatgat gaacaactga cataccattt ttaggtcttc
    10201 caattccaat cttaacacgg ttaaagacct gagttcctat atgttgaata atagacttga
    10261 taccattatg accacctgct gagccttttg ctcttaaacg aattttccca acttccatgt
    10321 caagatcatc gtaaatgata agtaaatcgt caatatccaa accatagtaa gttaataaag
    10381 catgaactgc ttttccactt tcattcataa aggtcgttgg tttaaccaga taaatttttt
    10441 ctccatttag gaaaaaggat gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga
    10501 cattctgttt cttcgctagt tgatcaatca acataaaacc aacattgtgt tttgtttcaa
    10561 aatatttatc ccctggattt cccaagccta caagtaattt ggtcatttat ttttcctttc
    10621 aaaagccaaa agggttggaa tttttttcca acctaattga caccatttat taatttttag
    10681 acattaaagc ggaattccat gatatcgcca tcttgaacga tatattcttt tccttcttca
    10741 cgcaagcgtc cagcttcttt tacggccttt tcagatccgt atttcactag atcttcatat
    10801 gacatggtta ctgcacgaat aaagcctttt tcaaagtctg agtggataat accagctgct
    10861 tgaggagcct tcataccacg tttgaaagtc caagcgcgaa cttctttttc accagctgtg
    10921 aagtaagttc ccaatccaag caagtggtaa gctgcacgcg tcaacttatc tacacctgat
    10981 tctgtcaaac caatggcttc aagaaactct tttttatctt catcatccaa ttcagaaatt
    11041 tcttcctcag cacgcgcaga aataacgact acttcagcat tttctgtcgc tgcaaattca
    11101 cgaatttgtt tgacatagtc gatagagtca ggttctgaaa ccacatcctc gtccacatta
    11161 gctacataaa gaactggttt agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc
    11221 tcatctgtaa attcaatggt acgagctgat ttcccgtctt ctaggactgg tttaatcttt
    11281 tgaagaacat tgaattctgc tactgattct ttatcttttt gcgtacgtgc catcttttct
    11341 acacgcgcat atcgtttgtt cactgattct aagtcagcaa gaattaattc cagattaatt
    11401 gtatcaatat ctgcaagtgg atctacaaag gcgtcttcac gtccttgctc gcgcatcaca
    11461 ttttcatcat caaaagcacg aactacgtga acaatcgcat ctacttcacg aatattggcc
    11521 aagaatttat tccctagccc ttctcctttt gaagctcctt ttacaatccc tgcaatatcc
    11581 gtaaattcaa atgttgtggg aactgtcttt ttaggagtta tcatttcagt tagtttttgt
    11641 aggcgttcat ctggaacttc caccattcca acatttggat caatagtcgc aaatgggtag
    11701 tttgctgcct ctgctcctgc ttttgtaatt gcattaaata gtgttgattt accaacgttt
    11761 ggcaaaccaa cgatacctgc tgtcaaagcc atatttctca ttctccgttt tcatttcaat
    11821 ccctaatatt ataacacaaa aagggataaa gtgctaaccc tctaactaag ggttctcagt
    11881 caataatttt attcattttt cgctcaaaat catatcgccc catcatgaca acatgctcac
    11941 aattactgca ttttattttg atatctgctc ctacacgtgt aatttcccaa cgattagcct
    12001 ttttaccagt cgacttgatt gtacaagcgt gtgatttttt catctcaaca aaatttccaa
    12061 cttgatacat actactctcc ttttcttttt cgattatatc ataaaagagg cgagccaggc
    12121 tcaacctctt tcacttaatt tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca
    12181 gtatctgctg gcacaagagt aaatggacga acagctgaga taaagctaat ggtcaccttt
    12241 tcgctattta aagctttaag agaatcaatc aagtaagttg ggttgaaact aatggtcaaa
    12301 tcttcaccag taacctgatc agtatcgatt tcttcgttta ctttaccaac ttctggagag
    12361 tgaacatggg cgctaacaac cccatcctta atttcaagtt tcacagtacc attttgagtc
    12421 gcacttgata aaagacgggc acgctccatt gactggcgta agtttaccac attaaaagta
    12481 atagtagtgt taaagtctgt tggaatcaag cgatctgtat caggatagtt tccttctagg
    12541 agacgagtat agaagctaat attttcgctt ctaaagagga tttggttatt ggcaaagaaa
    12601 atctctacag tttcgatatc atctgtaaat accgctgaaa attcgcgtag agaacggcta
    12661 ggaattacga catcaaaatc atcactattt ttttcaagag tcaatttttt ctggcttagg
    12721 cgatgagagt ctgttgcaac tgtttttaac tctttgtgtt gactcaatac gaagtggaca
    12781 cctgttaaaa tcggacgact ctcttgtgta cttgcagcaa aggctgtttc attaataatt
    12841 ttcttgagta attttgtttc aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt
    12901 ggatattgtt cgctatcttt tccttttagg gtaatttctg atttgccact ggttaaaaca
    12961 atttgatttt gttcaatttc tttaaaatca agagttacat caggtaaact agatactaca
    13021 ttgataaaga aagaagcttc aagaaggatc gaacctaaag aagtaattaa caaaccagca
    13081 tcttcatttt tttgagaaat aaaattttca attgaaattt gaccatttga accaattaaa
    13141 gtaatacctt cattggtcac gtcaattttt actgttgata aaataggaat ggcattttta
    13201 gaactaatag ctctcttagt agtatttaat gcttgtagaa ataaattttt attaattgaa
    13261 aaatgaatca tggattctcc tttatttatt tttagtatta gaaagataat agtaataata
    13321 gagtctgtga aatctgtgga aaacagcctt taaacaagtc atatcaagtt ttttagcttg
    13381 tttaaaaaat gtggataaaa aagataaaaa actaaaagtt atccacaaat tatttgattt
    13441 tctttttgat tgattcaatt tctaaacgta aattatcgtc ttgatcaatc aaagatttta
    13501 ttttggcatg ggcatgaatg actgtggtat gatcttttcc cccaaattcc ttcccaattt
    13561 ttggaagact attatctgtt agttctctag ataaatacat ggctacttga cgggccaaaa
    13621 caatattttg aaggcgtcta cttcccttca tttctttgat actaacacca taaaagttac
    13681 caacttcagt ttggatttta tcaattggga tgacgagcat ttggctaaca tcttgtttgc
    13741 gggctctaat ggcttctgca gcaatatcaa tagtgatatc cttgattttt tttactctgg
    13801 caattaaagt gatgtcgttg atggctccct caagatctcg aacatttgaa tcaaattgcc
    13861 cagctaggta ttctagagta tcactttgga aattgtagcc taaatgttcc gtcttacttt
    13921 gtaaaatggc aatacgtgtt tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac
    13981 taaaacgcgt gacaagcctc tcctcgagcc cttctagatg ttttggacta cgatcactcg
    14041 ttaggacaat ctgtttttgc ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct
    14101 gagttgcgac tttttttccg ctgagtgact gtatatcatc gattaacaaa agatcaagac
    14161 tacgataggt ctttttaaac ttttccattt ccccaagtct taggtgatca agaaagtcat
    14221 taataaagct ttcggcaggg atatatttaa cacgcgcatt aggaatattt tttagaattt
    14281 catttccaat agcgtttaat aagtgagtct taccaaggcc tggtcctcca tagataaaaa
    14341 gagggttata ggtcagagcc aaatcttcag agacagctaa agcggctgat acagcccaaa
    14401 catttccatc cccttgaata aagttatcaa aggtatactt ttcttttaat cccgtatctg
    14461 aataaggaat agatactaac tttggactat agtcataaag agttaaattt gtagcttctt
    14521 caacttgtga gctagtcgta tcttgaggtt tggtgaaaat atagtgggga gttatttcag
    14581 cgtcataaat ttcaaaacca gctactacaa taatatcttt tagttgtttt tcccagacca
    14641 tttccatttc agagcgaggt agaaatatag tggcaacatt ttcctctacc ttgatgagtt
    14701 cagcttgaat agcatagaaa tcatacatgg atcgagtcag tctttcttgt gcaaattcta
    14761 atatacgatt ccaaaattgt ttttctttca atcctttctc ctcctttact atttaaaagt
    14821 ttaatactag agatatttta ccatagatag caagaatttt ccacaagctg tgaaaaataa
    14881 tccacaatgt taccaaactt tatccacagg ttggggataa aagaagaaat tattgattta
    14941 ttaagctttt tatcgaaaaa catagtggat aaccttgtga gataaaaaaa taaaagaaca
    15001 gccttatttc aggctgttga taattctact atattcttct tgatttgaaa aagaaataat
    15061 gatttttcca ctgtcttttt tagatagttt aatttctaca tctaaaccga gtagttttct
    15121 taactgtttt tcttcatttt gtatgaaatg attagttttt tgctgtttct tttgtttttt
    15181 ctctgtcaga agagtttcta acttccttac agaaatatct tcttctataa tccgttgaaa
    15241 gaaatagtct tgttgttcct tatttaaccc aactagggaa cgcgcatggg cttgtgatag
    15301 tttgccattt tctacttctg agagaatctg ttctggcaag gaaagtaaac gaatggagtt
    15361 gctgatatat ggacgagact tgcccatctt atctgcaatt tcagcatggg tgaatccttt
    15421 ctctacgaga gattcatagg cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa
    15481 attttcaata atggactgga ccatcatctc ttggtctgaa atctgtttaa caacagctgg
    15541 gatagaccgt agaccagcta aaagtgaagc ccgatagcgt ctctctcctg caaggatttc
    15601 ataaccaata acaggagatt gacgaacaat aatcggttga atgaccccat tttctttgat
    15661 agactgtgct agttcatcta gtttttctct atcaaattct tttcggggtt gatagggatt
    15721 tttttgtata tctgtgatag aaatcatttc aaatttttcc atgattctac actaacacat
    15781 cttttctctt atgtaaagct ttctttacat agatgtcaat caagattcta aatcacctga
    15841 actcttgtta agtttgatag aggtagtttc ttctttcccg ttacgatagt aggttatctt
    15901 aatggtgtct ccgatagaat ggttgtaaag agcactttgt aagtctgttg atgaagcaat
    15961 ctctttgtca tctacttttg taattacatc gtatttttca aggtgaccat tggcaggcat
    16021 attactttgt accgaacgaa caactacacc agatgtaaca ttacttggaa tattgagtct
    16081 tctgatgtcg cttgtactca cattagataa attaaccatc tggattccca aagctggacg
    16141 cgtcactttt ccgttttttt ctaactgttc aataatattg atagcatcat ttgcaggaat
    16201 tgcgaaacca agaccttcta cagatgttcc tccatttgta gcaattttac ttgaggtaat
    16261 tccgataacc tgcccttgaa tattgatcag tgggccgcca gagttacctg ggttaatagc
    16321 agtatcagtt tggatggctt ttgtagaaat agcttgtcca tcttccgatc ttaaggatac
    16381 atttctattg agactggata cgataccttg agtgacagta tttgcatatt cagaacctaa
    16441 cgggctaccg atggcaatag cagtttctcc tacagttaac ttactagaat caccaaactc
    16501 agctactgtt gtcacttttt ctgaagagat tttgacgaca gcaatatcag agaaagtgtc
    16561 agctccgaca atttctccag gtactttagt cccatctgac aatcgaatat ctactttgct
    16621 ggcgccattt ataacgtgat tgttggtgac gatgtaagct tctttatcat tctttttata
    16681 aataactcca gatccttcac tagagattcg ctgagaatct gtgtcagtat catcattgcc
    16741 aaatacgcta ttttgtctgt ttgccgaata agtaataaca gaaacaacag catcttttac
    16801 tttgttaaca gcctgtgttg ttgaattttc gttcttatag gcagtttgtg taatagtact
    16861 attgttgtta gagttgttta cactactttt ttgagttagt tgagttattg aaaaactacc
    16921 caaggctcca ctaaaaaagc taatgacgat aacgactaat aattgaaacc attttttgta
    16981 aaatgttttt agatgtttca tatttgcctc catatgtttg aattactgaa agtataaact
    17041 gactagctta attataactt aaacacaaaa gttttacaca aactgtggat aactcttttg
    17101 aaactgtgat tttcttaatt gaaatctatt ttttattttg tgaataagat gtgaaaaaat
    17161 agagaatatg ttagaataga gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag
    17221 aaaagtattt aaaagatggt atcgcagagt attcaaaacg aatttctaga tttgctaagt
    17281 ttgaaatgat tgagttatca gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc
    17341 aaaagatttt agaaatagaa ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg
    17401 ttattgtgtt agccattgaa gggaaaactt tcttctcaga agaatttagt aagcagttag
    17461 aagaaacttc tataaaagga ttttctactc ttacttttat tattggggga agtttaggat
    17521 tgtcatcatc tgtaaaaaat agagccaatc tttctgtcag ttttggtcgc ctaaccttac
    17581 cccatcagtt aatgagacta gttcttgttg aacaaatcta tcgcgctttt acgattcagc
    17641 agggattccc ctaccataaa tagaaaattg acttttaatt gaatttttgg tagaataatt
    17701 gtattaggtc tcatagctca gctggataga gcattcgcct tctaagcgaa cggtcgcagg
    17761 ttcgaatcct gctgggatca atataatagc aaagctggga attttcccgg cttttttctt
    17821 aaaaaagtac actttgggag aaaaaaatga cagttgagag aattttatct aaaacgaaat
    17881 tccattttgt ataatggttt ttgtaagtta gcttacaaga aaaaacattt taggagattt
    17941 tattatgaaa aacacagtta aattggaata gtttgtagct ttgaaggaaa aagacttaca
    18001 aaagattaaa ggtggggaga tgaggttgtc aaaattcttc cgtgatttta ttttacaaag
    18061 aaaaaagtaa tgaaataagg ggaaagagta atggatttat ttggatttgg gacggttatt
    18121 gttcattttt taattattag tcacagttac cattttattt gtaaaggtca aataaataga
    18181 aaagaattat tcgtttttgg tgcttataca ttactaacag aaatagtatt tgattttccc
    18241 ttatatattc tatatttaga tgggttaggg attgaaagat ttttatttcc tttgggatta
    18301 tattcctatt ttcgatggat gaaacagtat gagagggata gaggactatt cctaagttta
    18361 ctactatctc ttttatatga gagcactcat aactttctgt ccgtaacttt ctcctctata
    18421 acaggagata attttgtttt acaatatcat ttcccattct ttttcgttgt gacggtgtta
    18481 acctattttg ttacattaaa aatcatttac tatttccatt tggaactagc ctattttgac
    18541 gaggactacc tttatccttt cttgaaaaaa gtattttttg ctttactatt gctacatatt
    18601 gtatctttcg tttcagatat ggtaagtacg attaaacatt tgaatagttt tggaagtatt
    18661 ttgtcatcta ttgtctttat ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa
    18721 gttcaaatgg agaaagagat tgctttgaag cagaagaaat ttgaacagaa acatttacag
    18781 aattacacag atgaaattgt tggtctgtat aatgaaatcc gtggttttcg acatgattat
    18841 gctggaatgc ttgtcagcat gcagatggca attgacagtg gtaatttaca ggaaattgac
    18901 agaatttaca atgaagtttt agtcaaagca aatcataaat tgcgttcaga taagtacact
    18961 tactttgatt tgaacaacat agaagactca gctttacgaa gtttggttgc tcagtcaatt
    19021 gtctatgctc gaaataatgg tgtagagttt acactggaag taaaagatac gattaccaag
    19081 cttccaattg aactattgga tttggttcgt atcatgagcg ttttattgaa taatgctgtc
    19141 gaaggatcgg ctgatagcta taaaaagcag atggaagtag cagttattaa gatggaaact
    19201 gaaacagtta ttgtgattca gaattcatgt aaaatgacga tgactccttc aggagatcta
    19261 tttgccttag gattctccac taagggaaga aatcgcggag tcggattaaa taatgtgaaa
    19321 gaactactag ataagtacaa caatattatt ttagaaacag agatggaagg cagtacattt
    19381 agacaaatca ttagatttaa gagggaattt gaatgaaagt tttaatttta gaagatgtta
    19441 ttgaacatca agtgagacta gagagaatat tggatgaaat ttcgaaagaa tcgaatattc
    19501 caatatcata caagacaacg ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg
    19561 aagtaaatca gctttatttc ctagatatcg atattcatgg aattgagaaa aagggatttg
    19621 aagtggctca gctcattcgt cattacaatc cttacgctat tatcgtcttt atcactagtc
    19681 gatcagagtt tgcgactcta acctataaat accaggtatc agccctagat tttgttgata
    19741 aggatatcaa tgatgagatg tttaagaaga gaattgagca aaatatcttc tacacgaaga
    19801 gtatgttact tgaaaatgaa gatgttgtag attatttcga ctacaattac aagggaaatg
    19861 atttaaaaat tccttaccat gatattttgt atattgaaac aacaggggta tctcataaat
    19921 tgcgcattat tggtaagaat tttgcaaaag agttttatgg taccatgaca gatattcagg
    19981 aaaaggacaa acatactcag cgattttatt ctcctcacaa gtcatttttg gtaaatatag
    20041 gcaatatcag agaaattgat cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt
    20101 gtcctatttc aagattaaaa attagaaaat taaaagatat tttagagaaa aaatctcaaa
    20161 agtgattgac aattagcaag aaattgatat aatggttata tctgctacag atagaaggtc
    20221 cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt
    20281 acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt aatcatgatg
    20341 tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct gtgttcctct
    20401 ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt tcttgagaac
    20461 tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca tgagttagat
    20521 agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat cgcttttgta
    20581 aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt tctttagtcc
    20641 cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca aaaacttcta
    20701 aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat gtatggaata
    20761 gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta tagaagctgg
    20821 aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca aatggctgtt
    20881 ccatcagtaa ttgtaccata gcattttcaa tagttcgctt tgtttttaag cgtttgttac
    20941 tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa tagatttttt
    21001 atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta gacaatatgt
    21061 ttaaaaaagg agaaactatg tttaaagaat ggaaagcaat ttaaaaaaaa caacctttat
    21121 tattgtcatg atcgggattt ctcttattcc agctctgtac aatatcatat ttttgtcatc
    21181 aatgtgggat ccatatgggc aattgtctga cttacctgtg gcagttgtaa ataatgataa
    21241 agaggcttcc tataatggta atactatggc aataggaaaa gacatggtgt ccaatttaaa
    21301 agaaaataaa accttggatt ttcattttgt agatgaagag gaaggaaaga agggattgga
    21361 agatggcgat tactatatgg tagtgacttt accaagtgat ttatctaaaa aaacaactac
    21421 attatccaat attcaatcga cagcagctta tcaatcattg acaagtgagc aacaaactgg
    21481 gataagtgat tctgtatctc aaaattcaac tgatagtatt caatcggctc agtcaattgt
    21541 agctttagta caaggtttac agggaagttt agaaaactta caaaatcaat cttctaatct
    21601 ttcgacttta aaaaatcaag ctaatcaagt attacctatt acttctactt ctttgatagg
    21661 attgtcaagt ggattaacag agatacaagg agctgttact agcaaattag ttcctgccag
    21721 tcagttgatt gcatcaggtg taaacgcata tactacaggt gttgataaag tttctcaggg
    21781 cgcaagtcaa ctaagtgaaa aaaatgccac cttgacaggt agtttggata aactagtttc
    21841 aggctcaaac accttgacac aaaaatcttc tagattgaca gcaggagtta gttaattaca
    21901 atcaggatct gggcaattag cagacaaatc cagtcagtta ctttcaggtg cttctccatt
    21961 agagaataga gctaataaat tggcagatgg atctgggaaa ctagcagaag gtggaacaaa
    22021 gttaacttct ggattggaag atttacagac aggacttgct tctttaggac aaggactagg
    22081 taatgctagt gatcaactca aatcagtatc aacagaatct aaaaatgcag agattttgtc
    22141 aaatccactc aatctttcaa aaacagacaa tgatcaagtt cctgtaaatg taatcgcaat
    22201 agctccttat atgatatcag ttgctctttt tgttgcagca atatcaacaa atatgatatt
    22261 tgcgaaattg ccttcaggac gtcatccaga gagccgttgg gcttggttga aatcttgagc
    22321 tgaaataaat ggtattatag ctgttttggc aggaattttg gtatatggag gagttcagct
    22381 tattggttta actgctaatc atgagatgag aatatttatt ctcatcatcc taacaagttt
    22441 agtattcatg tctatggtga ccactttagc aacgtggaat agccgtatag gagctttttt
    22501 ttcacttatt ttgcttttac tacagttagc atcaagtgca ggtacttatt cacttgcttt
    22561 gacaaatgat ttctttagat ctattaatcc ctggttacca atgagctatt cagtttcggg
    22621 attacgacaa acaatctcta tcaacaagtc attttcctag ctgtcatact agctctattt
    22681 actggtttag gtatgctagc ctatcaacat aagaaaatgg aagaagatta aaaaaatcga
    22741 ccgattaact ggtcgatttt ttatgcctta gatgactttc gtctgtgatt atagattcca
    22801 aatagtaaga gagaagtaaa ggaacagatt gctccagtca taaaaccatt gggaatgaag
    22861 gaaagtgtaa tagttccttt ccccttggga atgtcaactt tcataaatcc agtttgagct
    22921 tgtttaattt ctattttctt accatcttgg taggcagacc aacctttgtc ataaggaatg
    22981 gtgaagaaaa tagatgtatc ttgttggaca tcatatgtag caaaaacctt gtttttagaa
    23041 gttgatactg tgacaggttg ttctttaatt ttttgaattg cctcggtgaa agttttggta
    23101 tctaaacgat agaaggtagg agattcaaat gatacttgtg aatttccagg gaaactaaca
    23161 ttgatattga aagttttttt ctctttagta tatcctagat taaagaagga gaagacatta
    23221 tcagttgtaa aagtcttttt ttcaccattt acaaggatgt caaccttctt ttgtttatcg
    23281 ttagaaaagt gaaggtttat gaaagagaga taaacttggc tgttttctgg aacttcaatt
    23341 tgatactgga ttgctgcatc ttcatttgaa gaacttgtga cactaatcaa atcattagta
    23401 ttttctattt tttctgtttt ttcataaggt attggagaaa aataatcaaa attgacgtta
    23461 gcaagttgat ttaaaaatga ggcctgatta tccaaggtat gttcattgaa cttgacatca
    23521 ttgtaaacag attgactagc aactgcaatc ggaagagagt attgattttc atatagggta
    23581 agattatctt tttgatagat atctttaaag ccatacttat caataggact gtctgagata
    23641 ttgtactgga taccaaataa actatcagcc aaaatactat tatttgcata tcggagattg
    23701 agattagtcc cagaggattt aaaaccaagt ttatctaaag tagagcttga tgaacgattt
    23761 cgaacagatg aaaattgaga gattccattg tagttgaatt tcatactgtc atttcctgtc
    23821 tgagtttgta gtttttcagt acgagtaaat tgatttccaa tatatgttga gaaagattcc
    23881 atagctggga tatctcgact ataagcactt cgagaagcaa atccccattc cttagcaatt
    23941 ccgtccattt gagatgaagc atttaaactc atttcaacca gtataaataa agagattaga
    24001 atggcaaata gattcacaga tataaacttt ttgataactg caaggagtaa aagagaatag
    24061 acaaccaaaa attcaagagt aagcagaata ttcaaatctg ttaaaaaaga ataatgcgat
    24121 tttagataga tggtagctaa aaatcctgct actacaagaa aaagcgaaac taaaaaattc
    24181 cagactttaa gttctttcag acgctttaag acttctgctg ctgtgtaaat taacaaggta
    24241 gagaaaatcc aagcatagcg atgtaaaaac atgtttggag tatgcatgcc ttgccaaaat
    24301 aagtcaagag cttctatgta aaagcttgca attagaaatg caaagaatat tacatatatg
    24361 agtttcacgt gaaacttaat agatttcagc gtaaaaaata aaatggtcaa aataaaggga
    24421 aatagtccaa caaaaatcat tgggatggcc ccatactttg ttgtgtcaaa ggaaccaatg
    24481 aattgcttag caaagagatc aagataccag ctactttcag tttgaaactt tgtaacttca
    24541 gtcaattttt ccccatgtgt ctgtaaatca aatagagtgg gaagagtcat aatcaaacta
    24601 gccataccag ctaaaaagga gataactatg aaatcaagaa cagatgattt tcgagtctta
    24661 aagtcccacg aaatttgaca gagataccag aaaataagaa acaatactgt catatatcca
    24721 aaataataat tttgaataaa taagattgac agacttgtaa agtacaatag gagtttcttt
    24781 tcagttatca gtagatgtaa accagttata attaaaggaa tcaagataaa aacatctagc
    24841 caggttttta tctctaattg actgacagtg aaactcatca gagcatagga agtagataag
    24901 gctagtttta aagtctgagg gatagattga aacaatttat tcaaactaaa aaaggttgac
    24961 agaccaatca atccaaattt taagagagtg gtcagataga cagcacctgg catattcgtt
    25021 agatcaaaaa agtaaactag aggcgcgaga aaactaccca agtaataact agatagggca
    25081 tagaagttta gccctagacc acttgtaaag gtgtaaaaca gactactatt tccatgtagg
    25141 atatttcgta aggctacatc aaaaataacg tattgatgaa agccatctcc taatagagga
    25201 gagttgtcgc tattccagta gataccttga gatagatata ctccagacat aatcactaca
    25261 ggaatgatga aagaaataaa ataggttcga tatgttttta aaaatgattt catgttacct
    25321 cgtagaatga tagaaaactc agttggttaa cccaactgag ttttgaagtt ttatttagtc
    25381 tttccaaagt tctttaactt ttgcttgtac ttctgcattt tctaggaatt catcgtaggt
    25441 ttcatcgata cggtcaatga cgccattttt agataagaca atgatatggt tagccaaagt
    25501 ttgaataaat tcgtggtcat ggctagcaaa gatgattgat tctttaaagt ttttcaatcc
    25561 atcattcaag cttgagatag attccaagtc caagtgattt gttggatcat caagtacaag
    25621 gacatttgat tttaagagca tgagttttga aagcatgaca cgaacttttt ctccccctga
    25681 caagacattt acaggtttgt taacttcatc tccagagaag agcatacggc cgaggaagcc
    25741 acgtaggaaa gtattgtcat cttcttcttt acttgcgaat tgacgcaacc agtcaagaat
    25801 tgattctcct cctgcaaaat cagctgagtt atcttttggt aggtaagatt gactagttgt
    25861 aactccccac ttgacagttc cttcatagtc aatatctccc atgattgcac gaattaatgc
    25921 agtcgtttga atatcatttt gtccaataag tgctgtctta tcatctggac gcaagatgaa
    25981 actaatatta tccaagatag tttcaccatc aatctttaca gttagatttt ctactgtcaa
    26041 gagatcatta ccaatctcac gttccgcttt aaagttgata aatggatatt tacgactaga
    26101 tggcacaatc tcttctaact caatcttatc aagcattttc ttacgtgatg ttgcctgcct
    26161 tgacttagaa gcattggcag agaaacgagc aacaaattct tgcaattgtt taattttttc
    26221 ttctgcttta gcattacggt ctgctagcaa tttagcagca agctcagaag attccttcca
    26281 gaagtcgtag tttccgacat agagtttgat ttttccaaag tcaaggtcgg ccatgtgagt
    26341 acaaactttg tttaagaagt gacggtcgtg ggatactacg ataactgtgt tatcaaagtc
    26401 aatcaagaag tcttctaacc aagtaatcga ttggatatcc aaaccgttag taggctcgtc
    26461 caagagaaga acatctggtt taccaaaaag tgctttggcg aggagaacct ttactttttc
    26521 accgttggcc aattcgctca tgttttggta gtgtaattct tctggaatgt ttaggttttg
    26581 aagtagttga gaggcttcac tctctgcttc ccaacctcca agttcggcaa actctccttc
    26641 gagttcggca gcacgaaccc cgtcctcgtc tgagaaatct tccttcatgt agatagcatc
    26701 tttctctttc atgatgctat aaagtttttc atttcccatg ataacgacat caatggcacg
    26761 ttcatcttcg tagtcaaagt gattttgacg aagaacagag agacgttcat ctggaccaag
    26821 agagatgtga ccagtagtag gttcgatatc tccagctaaa atttttaaaa aggttgattt
    26881 tccggcacca ttagcaccga ttaatccgta agtatttcct tctgtaaatt tgatattgac
    26941 atcatcaaaa agtttgcgat cactaaaacg tagtgaaaca tcagatactg taagcaatgt
    27001 ttttctccta tatgtgtaat atatttattc tactagaaaa tacagaaata ttcaaatttt
    27061 tatttgtcaa ttttgtgtaa attatattta cagtatcctt tacacaaatc tgtaaaaagc
    27121 aaggctgatt tattttgata aattacggtt atttcattta aaaaatgcta taattgaaag
    27181 gactatatcg aaggagaaca aaatgactaa acccattatt ttaacaggag accgtccaac
    27241 aggaaaattg catattggac attatgttgg aagtctcaaa aatcgagtat tattacagga
    27301 agaggataag tatgatatgt ttgtgttctt ggctgaccaa caagccttga cagatcatgc
    27361 caaagatcct caaaccattg tagagtctat cggaaatgtg gctttggatt atcttgcagt
    27421 tggattggat ccaaataagt caactatttt tattcaaagc cagattccag agttggctga
    27481 gttgtctatg tattatatga atctagtttc gttagcacgt ttggagcgaa atccaacagt
    27541 caagacagag atttctcaga aaggatttgg agaaagcatt ccgacaggat tcttggtcta
    27601 tccaatcgct caagcagctg atataacagc tttcaaggct aattatgttc ctgttgggac
    27661 agatcagaaa ccaatgattg agcaaactcg tgaaattgtt cgttctttta acaatgcata
    27721 taactgtgat gtcttggtag agccggaagg tatttatcca gaaaatgaga gagcagggcg
    27781 tttgcctggt ttagatggaa atgctaaaat gtctaaatca ctaaataatg gtatttattt
    27841 agctgatgat gcggatactt tgcgtaaaaa agtaatgagt atgtatacag atccagatca
    27901 tatccgcgtt gaggatccag gtaagattga gggaaatatg gttttccatt atctagatgt
    27961 ttttggtcgt ccagaagatg ctcaagaaat tgctgatatg aaagaacgtt atcaacgagg
    28021 tggtcttggt gatgtgaaga ccaagcgtta tctacttgaa atattagaac gtgaactggg
    28081 tcctattcgt gagcgccgta ttgaatttgc taaggatatg ggagaagttt ataatatgat
    28141 tcaaaaaggt agtgaaagag cgcgtgaagt tgcgggtcaa accctatctg aggtaaaagg
    28201 ggcaatggga cttcattact ttaactaagt ttattttaca agaaactatc ttttctatct
    28261 cgaagaaaag atagtttttt atttacccct gtaacatttg acaaattttt atagaatggt
    28321 atgatagata caatataaaa agagtcaagc tcaaaaagaa agaaaagagg aaacttcgaa
    28381 tgtctaattg ggacactaaa tttttgaaaa aaggttttac ctttgatgat gtattgctta
    28441 ttccagctga aagtcatgtg ttgcctaacg atgcagattt aacaactaaa ttggcagata
    28501 atttgacttt aaatatccca attattaccg ctgccatgga cacagttaca gagagtcaaa
    28561 tggccattgc tattgctcgt gcaggcggtc tcggagttat ccataaaaac atgtcaattg
    28621 ctcaacaagc agacgaggtt cgtaaggtaa aacgttctga aaatggagtt attattgatc
    28681 cgttcttctt gacgcctgaa catacaattg ctgaagcaga tgagcttatg ggtcgttacc
    28741 gcatcagtgg tgttccagtt gttgaaacac ttgaaaatcg taaattggtt ggtattttga
    28801 caaaccgaga tcttcgtttt atttcagatt ataatcaacc aatttcaaac catatgacta
    28861 gtgaaaatct tgttactgct cctgtgggta cggatcttgc aacggctgag agtattcttc
    28921 aagagcatcg tattgaaaaa cttccgttgg tcgatgaaga aggcagtctt tctggtttga
    28981 tcactatcaa agatattgaa aaagttattg agtttccaaa tgcagctaaa gatgagtttg
    29041 gtcgtcttct agttgcaggt gcagtaggtg ttacttcaga tacatttgaa cgtgcagagg
    29101 ctctttttga ggcaggagcg gatgcgattg ttattgatac tgcacatggt cattctgcag
    29161 gtgtcttgcg taaaattgcc gagattcgtg ctcatttccc agatcggact ttgattgctg
    29221 gaaatattgc tactgctgaa ggtgcacgtg ccctttatga agcgggtgta gacgttgtta
    29281 aggttggtat tggaccaggt tctatctgta ctactcgtgt gattgctggt gttggtgttc
    29341 cgcaagtaac agctatctac gatgctgcag ctgttgcgcg cgaatatggt aaaacgatta
    29401 ttgctgacgg tgggatcaag tattctggag atattgtaaa agcacttgct gcaggtggaa
    29461 atgctgttat gcttggatct atgtttgctg gaactgatga agctccaggc gaaactgaaa
    29521 tcttccaagg acgtaaattc aagacttacc gtggtatggg atcaattgct gctatgaaga
    29581 aaggttcaag cgaccgttat ttccaaggtt ctgtcaatga agcaaacaag cttgttccag
    29641 aaggaattga aggtcgtgtt gcttataaag gagcggcagc tgatattgtt ttccaaatga
    29701 ttggtggtat tcgctctggt atgggttact gtggtgcagc taaccttaaa gaactacacg
    29761 ataatgctca atttattgaa atgtctggtg ctggtttgaa agaaagccat cctcatgatg
    29821 tgcaaattac taatgaggca ccaaattatt ctatgtaaaa aacaatgaaa agaactccag
    29881 tgaaaacagg agttctttta caatggtgtc aatttccatt tacagcaact ttaccatcct
    29941 gaatagtgaa gatacttaga ttttctggca gattttgaag atggtctaag cttgttgttg
    30001 tgataaaggt ttggattgat tgagaaatcg tttctaataa ttttaactgt ctagtgttgt
    30061 caagttcact catcacatcg tcaagcagta atataggaga ttctgtggta atgctttcca
    30121 ttaattcgat ttctgctaat tttatcgaga ggacgagact acgatgttga ccttggcttc
    30181 cgaaactagc atccatccca tttatataaa aagaaatgtc atctcgatga ggaccgacac
    30241 cagtattctt tttaaataaa tctctggatc tacttttttc taaagcaatt ttgaaagatt
    30301 cggataagtt ttgtttgtca gttatattga cagaagattg ataggatatt gacaactctt
    30361 cgatctgatt agagagttca aaatgtttct tacgcccaaa tgattctagt ttttttatga
    30421 aatctaagcg gtgattcatt acacgacatc cataatcaac tagctgatca tctaacacag
    30481 aaaggaatgt ttcatctatt ttttgagctg attttaggta agtgtttctt tgctttagga
    30541 tgtggttata attggttaag tcagataaat agattggctt aatttgccca agttccatat
    30601 caatgaattt tcgtcgaatc gaaggtgctc ctttaattag ttgtaaatct tcaggagcaa
    30661 ataagacaac attcatgtgt cctacataat ctgaaaggcg tgcctgtttt aagtgattaa
    30721 cttttgttac acgacctttt tgtgttagtt cgatttctag gggaatggat ccagtttttt
    30781 tctgaacgag acctgaaaga tgaagttgtt cctcatcaaa atgaatgaga tttttatctg
    30841 ttcgagttcg atgactacgc gttaaggcta aaaaatagat agcctctaac atgtttgttt
    30901 ttccttgtgc attacgtccc aaaaagacat tcaatttagg attaaagtct attttcgttt
    30961 ctttgtaatt acgaaaagtc ttgagagata gatgttgtag ccacatgatt atctaccagg
    31021 gaatcgtgga gcttgttggc ttttaggtga tgaagcaggt ttcgatttgt cttttttaac
    31081 tcccttattc atctttttga caagtttagc gatccgttct ttttcaactt tatcagcttg
    31141 gtattcatct tgttcttcag aagtaggttg tgtcaacaag atgtcaatgt tcatgtcagg
    31201 gatgtcaact ttatcgccaa tacgaagttt ttttccacga cggctctcta attccctatt
    31261 aaagtaaaca gaatgttcag agagaaatga tttaatagct cctccgctat gtgtaattcc
    31321 aagttctttg aatagtgctt ggagggtaat aaattcttca aataatttgt attccataat
    31381 tcacctcaat ctttggtatt ataccatatt ttcctaaaaa tagtgagaga gacagcgaga
    31441 aatgtaagcg atttttattt caaaagtgtt acagggaaca agaaaatttc aggttttcgt
    31501 gatataatag aagtctgtat ataaggaggt aaatcatgga gttagtgcat ggaatttcaa
    31561 cacattttat ccaatcaaaa aagtttaaaa caaacaaaat taccgtgcgt tttaccgctc
    31621 cattatccct tgatacgatt gcaggtcaca tgttgagtgc aagtatgcta gagactgcta
    31681 atcagatgta ccccacttct caagatttga ggagacactt ggccagtcta tacggtacag
    31741 atatgtcaac caattgtttc agaagagggc aaagccacat tatagaattg acatttacct
    31801 atgttcgtga tgagttttta agtaggaaaa acgtgctaac ctctcagatt ttggaacttg
    31861 taaaagaaac tcttttttca cccgtagtag ttgataatgg gtttgatccg gccttatttg
    31921 aaattgagaa aaaacaattg ctagcaagtt tagcagctga tatggatgat tctttttatt
    31981 ttgcacataa agaattggat aaattgtttt ttcatgatga acgtcttcaa ttggaatata
    32041 gtgatttacg aaatcgtatt ttagctgaaa ctccacaaag ttcttattct tgtttccaag
    32101 aatttttagc caatgatcga atagatttct ttttcctagg tgattttaat gaggttgaaa
    32161 ttcaaaatgt attagaatca tttggcttta aaggtcgaaa aggagatgtg aaggttcagt
    32221 attgtcaatc ttattctaat atccttcagg aaggtatggt tcggaaaaat gtgggacaat
    32281 ccattttgga attaggttat cattaccgtt ctaaatatgg tgatgaacaa catttaccca
    32341 tgattgtaat gaatggttta cttggtggat ttgctcactc taagctcttt acaaatgtcc
    32401 gtgaaaatgc tggattagct tataccattt caagtgagct tgatttattt agtggattct
    32461 tgaggatgta tgctggtatc aatcgagaaa atcgtaacca ggctcgtaaa atgatgaata
    32521 atcaactgct tgatttaaaa aaaggttatt ttacagagtt tgagttaaat cagaccaagg
    32581 aaatgattcg ttggtcgttg ttactttctc aagataatca atcttcattg attgaacgtg
    32641 cttatcaaaa tgccttattt ggaaaatctt cagcagactt taaaagttgg attgcaaagc
    32701 ttgaacaaat tgacaaagat gctatttgta gagtagctaa taatgtgaaa ctacaagcga
    32761 tttactttat ggaaggaata gaatgacaaa ggttgttttt gaagaaaaat actatccagc
    32821 tgtaaaagaa aaggtttatc gaactcgttt ggccaacgga ttgacagttg ctcttttgcc
    32881 taaaaaggaa tttaaagagg tttacgggag tgtaactgta cagtttggtt cgatagatac
    32941 gcttgtcaca gaagttgacg gagatgtaaa acaatatcct ggaggaattg ctcattttct
    33001 tgaacataaa ttatttgaga gagaagattc tagtgatttg atgtcggctt ttacgagtct
    33061 aggtgcagat agtaatgcct ttacaagctt tacaaaaaca aactatcttt tttcagcaac
    33121 ggattatttt ttagaaaatt tagatttact tgatgaattg gtaacatcag cacactttac
    33181 tgaagcttcc attctgacag agcaggatat tattcagcaa gaacgagaaa tgtaccaaga
    33241 tgatccagat tcgtgtttat tcttttcaac tttagcgaat ttgtatcctg gtacaccttt
    33301 agcaactgat atagttggaa gtgaggagtc catttcccaa atcaatctaa ctaatttgca
    33361 agaaaatttt acaaagtttt acaaacctgt aaacatgtct ctgtttttag ttggtaattt
    33421 tgatgtggag cgagtacagg actattttga aagcaaagaa ctgaaagatt cagattttca
    33481 ggaagtagca agagaaaagt tgtttttaca gcctgtaaag ccaacagata gtatgagaat
    33541 ggaagtatct tctcccaaac tagcgattgg agttagaggt aagcgagaag tttctgaagc
    33601 ggattgctat cgacatcata ttttattaaa attattgttt gcaatgatgt ttggttggac
    33661 ttcggatcgt tttcaaaaat gttatgaatc aggtaaaatt gatgcgtcct tatctctgga
    33721 agttgaaata acaagtcgct ttcattttgt catgttgaca atggatacga aagagccagt
    33781 tgctttgtct catcaattta ggaaggctat tcgtaatttt acaaaggatt tagatattac
    33841 agaggaacat ttagatatta tcaaaagaga gatgtttggc gaatttttca gtagcatgaa
    33901 ctctcttgaa tttattgcaa cgcaatatga tgcttttgaa aatggtgaga caatttttga
    33961 tttgccgaaa attttacagg aaattacttt agaggatgtc cttgatgctg gacatcattt
    34021 aatagatgat ggtgacatag ttgattttac aatattccca tcgtagtaac ctatcataat
    34081 agacactaga aagaagggat gacaagtatg agaaaaaaaa caattggaga ggttttacga
    34141 ttagctagaa tcaatcaggg attgagttta gatgaattgc agaaaaagac agaaatccag
    34201 ttagatatgt tggaagcaat ggaagcagac gatttcgatc aacttccaag tcctttttac
    34261 acgcgttctt tcttgaaaaa atatgcatgg gctgttgagt tagatgacca aattgttttg
    34321 gatgcttatg attctgggag tatgattact tatgaggaag tagatgttga tgaagatgag
    34381 ttgacaggtc gtagacgttc aagtaagaaa aagaagaaaa aaacatcatt tttaccttta
    34441 ttttatttta tcctttttgc tttatcgatt ttaatttttg tgacttatta tgtttggaac
    34501 tatattcaaa ctcaaccaga ggagccttct ctttctaatt acagtgtggt tcaatcaaca
    34561 agttcaacta gctctgttcc ccactcctca agtagtagtt cttctagtat agaatcagct
    34621 ataagtgtat caggcgaagg aaatcatgta gaaatcgctt ataagacaag taaggaaaca
    34681 gttaaattgc aattggcagt ttcagatgtt acaagttggg tcagtgtttc agaaagcgaa
    34741 cttgagggcg gtgtaacctt atcgccaaag aagaaaagtg cagaagcaac agttgcaact
    34801 aaaagtcctg taacaattac gttaggtgtt gtaaaaggtg ttgatttgac agtagataat
    34861 cagactgttg atttatcgaa attaacagct cagactggac aaatcactgt aacctttact
    34921 aaaaattaag gaaaaacgaa tgaaaaaaga acaaattccc aatctcttaa caataggtcg
    34981 aattctcttt atacctattt ttatctttat tttaacgata ggaaattcga tagagagtca
    35041 tatagttgca gctattatct ttgctgttgc cagtattacc gactatttag atggatattt
    35101 agctcgtaaa tggaatgtgg tcagtaattt tggtaaattt gcagatccta tggcggataa
    35161 gttactagtt atgtcggctt ttattatgtt gattgagtta ggtatggctc cggcttggat
    35221 tgttgcagtg attatctgtc gtgagttagc tgtgacaggt ttaaggcttt tattggttga
    35281 aactggtgga acaattttag cagcagcaat gcctggaaaa attaaaactt ttagtcagat
    35341 gtttgccatt attttcttgc tattacattg gactttgctt ggtcaagttc tactttatgt
    35401 agccttattt ttcactatct actctggcta tgactatttc aagggtagtg cctatgtatt
    35461 taaagggaca tttggttcga aatgaaatca ataattgatg taaaaaatct ttcttttcgc
    35521 tataaagaaa atcagaacta ctacgatgtg aaggatatta cgtttcacgt gaaacgtgga
    35581 gaatggcttt cgattgtagg gcataatggt agtggtaaat caacgacggt tcgattaatt
    35641 gatggcttac tggaagcaga atccggagag attgtaattg atggccaacg tttgactgag
    35701 gaaaatgttt ggaatatacg tcgtcaaatc ggtatggttt ttcaaaatcc agacaatcaa
    35761 tttgttggag cgactgttga agatgatgtt gcttttggtt tggaaaatca gggactttct
    35821 cgtcaagaaa tgaaaaagag agtagaagaa gctctggctt tagttggcat gttggacttt
    35881 aaaaagagag agccagcgcg tctatcaggt ggccaaaagc aacgtgtggc cattgcaggt
    35941 gttgtagccc taagaccagc tattttaatc ttagatgaag caacgagtat gttggatcct
    36001 gaggggcgta gagaacttat tgggacagta aaaggaattc gaaaagacta tgatatgacg
    36061 gtcatttcta ttacccatga tttggaagaa gtcgccatga gtgatcgcgt attggtcatg
    36121 aaaaaagggg aaattgaatc aactagtagt ccaagggagc ttttctctcg aaatgattta
    36181 gatcaaattg gattagacga tccttttgct aatcaattaa aaaaatcttt gagccagaat
    36241 ggctatgatt tacctgaaaa ttatttgaca gaaagtgagc tagaggataa gctatgggaa
    36301 ttgctctaga aaatgtgaat tttacatatc aagaaggtac tcccttagct tcagcagctt
    36361 tgtcggatgt ttctttgacg attgaagatg gctcttatac agctttaatt gggcacacag
    36421 gtagtggtaa atcaactatt ttacaactct taaatggttt attggtgcca agtcaaggga
    36481 gtgtgagggt ttttgatacc ttaatcacct cgacttctaa aaataaagat attcgtcaaa
    36541 ttagaaaaca ggttggcttg gtatttcagt ttgctgaaaa tcagattttt gaagaaacgg
    36601 ttttgaagga cgttgctttt ggaccgcaaa attttggagt ttctgaagaa gatgctgtga
    36661 agactgcgcg tgagaaactg gctctggttg gaattgatga atcacttttt gatcgtagtc
    36721 cgtttgagct gtcaggggga caaatgagac gtgttgccat tgcaggcata cttgccatgg
    36781 agccagctat attagtctta gatgagccaa cagctggtct agatcctcta gggagaaaag
    36841 agttgatgac cctgttcaaa aaactccacc agtcagggat gaccatcgtc ttggtaacgc
    36901 atttgatgga tgatgttgct gaatatgcaa atcaagtcta tgtaatggaa aagggacgtt
    36961 tagtaaaggg gggcaaacca agtgatgtct ttcaagacgt tgtttttatg gaaaaagttc
    37021 agttgggagt acctaaaatt acggcctttt gtaaacgatt ggctgataga ggcgtgtcat
    37081 ttaaacgatt accgattaag atagaggagt tcaaggagtc gctaaatgga tagtatgatt
    37141 ttggggcgtt atatcccagg ggattcgatt gttcaccgat tggatccacg tagcaaattg
    37201 cttgctatga tgctactgat tttgattgtg ttttgggcta ataacccctt gacgaatctg
    37261 attcttttta tagcgacagg gatatttatt gccttgtcag gagtatctct ttcatttttt
    37321 attcagggct tgaagtctat gtttttcttg attgccttca caactatttt tcaactattt
    37381 ttcatttcta atgggaatgt tttatttgag ttttcgtttg tgagaatcac ggattatgct
    37441 ttgcaacaag ctgggattat tttttgtcgc tttgtattga ttattttctt ttcaactttg
    37501 ttaaccttaa caaccatgcc tttaagtttg gcatcagctg tcgaagcttt attagcacct
    37561 ttaaagcgtg tgaaagttcc agttcatgaa attggattga tgctgtctat gagtttgcgt
    37621 tttgtcccaa ccttgatgga tgatacgact cggattatga atgcacagaa agctcgtgga
    37681 gtggattttg gagaaggaag catcgttcaa aaagtaaagg cgatgattcc cattttgatt
    37741 cctctttttg cgacaagttt aaaacgtgca gattccttgg ctatcgctat ggaagcgcgt
    37801 ggctatcagg gtggaaaagg cagaagtcaa taccgacaat tgaaatggac tctaaaggat
    37861 acgctgacca ttcttgttat tctcgtactt ggttgttgtt tatttttctt aaaatcttag
    37921 tagctttcag gaattgataa aaagttactg taacagtttt tgatagaaag gtagggatat
    37981 gaaccgtttt aaaaaatcaa aatatgtcat tattgttttt gtcactgttc tgcttgtgtc
    38041 agctctctta gcgacgactt attcaagtac aattgtgaca aaattaggag atggaatctc
    38101 attggttgat agagttgtac aaaaaccttt tcagtggttt gattctgtca aatcagattt
    38161 ggctcatttg acacgaacat ataatgaaaa tgaaagtttg aagaaacagc tttaccaatt
    38221 agaagttaaa tcaaatgagg tggaaagttt aaagacagaa aatgaacaac tgcgccaatt
    38281 gcttgatatg aagtctaaat tgcaagccac aaagacttta gcagcagatg ttattatgcg
    38341 ttctccggta tcttggaagc aggagttgac cttagatgca ggtagatcaa aaggtgcttc
    38401 tgagaacatg ttagctattg caaatggtgg cttgattggg agtgtttcaa aagtagagga
    38461 gaactctact atagtcaacc ttctgacaaa tacggaaaat gctgataaga tttctgttaa
    38521 aattcaacat ggctctacta caatttatgg aattattatt ggctatgaca aggaaaatga
    38581 cgttcttaaa attagccaat taaatagtaa tagcgatatt agtgcgggag ataaggtgac
    38641 tactggtgga ttaggaaact ttaacgttgc tgatattcct gttggtgaag tggttgccac
    38701 aacgcatagt acagactatt tgacacgaga agtaactgtt aaattgagtg cagatactca
    38761 taatgtagat gtgatagaat tagtggggaa ttcataatga gacagttgaa gcgagttgga
    38821 gtatttttat tgcttccttt ctttgttcta attgacgccc atattagcca gcttctgggc
    38881 tcatttttcc cccatgtaca tttggctagt cattttcttt ttctatttct cttatttgag
    38941 acgatagaag tatcagagta tctctaccta gtctattgtt ttgctatagg cttggtttat
    39001 gatgtttact ttttccatct aatagggatt acaactctct tatttatctt attgggagcc
    39061 ttccttcata aattgaatag tgttattttg ttgaatcgtt ggacaagaat gctagctatg
    39121 attgtgctga cattcctgtt tgaaatgggt agttatcttt tggcttttat ggtagggttg
    39181 acagtagata gcatgtcgat ttttatagtc tatagcttgg taccgacgat gattttaaat
    39241 tttttatgga ttactgtttt tcaatttatt tttgaaaaat attatctata agaacgacat
    39301 ataaatgtaa caaaggcgta atatttatta ggcctttttt tggtatacta gtattgtctt
    39361 taaaagaagg agtatctacg taatatgaag aaaaaaatct tagcgtcact tttattaagt
    39421 acagtaatgg tttctcaagt agctgtttta acaactgcgc atgcagaaac gactgatgac
    39481 aaaattgctg ctcaagataa taaaattagt aacttaacag cacaacaaca agaagcccaa
    39541 aaacaagttg accaaattca ggagcaagta tcagctattc aagctgagca gtctaacttg
    39601 caagctgaaa atgatagatt acaagcagaa tctaagaaac tcgagggtga gattacagaa
    39661 ctttctaaaa acattgtttc tcgtaaccaa tcgttggaaa aacaagctcg tagtgctcaa
    39721 acaaatggag ccgtaactag ctatatcaat accattgtaa actcaaaatc aattacagaa
    39781 gctatttcac gtgttgctgc aatgagtgaa atcgtatctg caaacaacaa aatgttagaa
    39841 caacaaaagg cagataaaaa agctatttct gaaaaacaag tagcaaataa tgatgctatc
    39901 aatactgtaa ttgctaatca acaaaaattg gctgatgatg ctcaagcatt gactacgaaa
    39961 caggcagaac taaaagctgc tgaattaagt cttgctgctg agaaagcgac agctgaaggg
    40021 gaaaaagcaa gtctattaga gcaaaaagca gcagctgagg cagaggctcg tgcagctgcg
    40081 gtagcagaag cagcttataa agaaaaacga gctagccaac aacaatcagt acttgcttca
    40141 gcaaacacta acttaacagc tcaagtgcaa gcagtatctg aatctgcagc agcacctgtc
    40201 cgtgcaaaag ttcgtccaac atacagtaca aacgcttcaa gttatccaat tggagaatgt
    40261 acatggggag taaaaacatt ggcaccttgg gctggagact actggggtaa tggagcacag
    40321 tgggctacaa gtgcagcagc agcaggtttc cgtacaggtt caacacctca agttggagca
    40381 attgcatgtt ggaatgatgg tggatatggt cacgtagcgg ttgttacagc tgttgaatca
    40441 acaacacgta tccaagtatc agaatcaaat tatgcaggta atcgtacaat tggaaatcac
    40501 cgtggatggt tcaatccaac aacaacttct gaaggttttg ttacatatat ttatgcagat
    40561 taatttacag agggactcga atagagccct cttttcaggt tttaccgtga caatccctat
    40621 taaaaattat atcaaaatag cttgaaaata ttggaaaagt atggtagaat gaaaattgtc
    40681 gtgtgaacga taatactcat tcttgatgaa ttgtgaagca gttgcccttg ggtcgttttg
    40741 cgagttgaag tcaagaagag gaaaaaaaca aaaaggagaa atactcatgg cagtaatttc
    40801 aatgaaacaa cttcttgagg ctggtgtaca ctttggtcac caaactcgtc gctggaatcc
    40861 taagatggct aagtacatct ttactgaacg taacggaatc cacgttatcg acttgcaaca
    40921 aactgtaaaa tacgctgacc aagcatacga cttcatgcgt gatgcagcag ctaacgatgc
    40981 agttgtattg ttcgttggta ctaagaaaca agcagctgat gcagttgctg aagaagcagt
    41041 acgttcaggt caatacttca tcaaccaccg ttggttgggt ggaactctta caaactgggg
    41101 aacaatccaa aaacgtatcg ctcgtttgaa agaaattaaa cgtatggaag aagatggaac
    41161 tttcgaagtt cttcctaaga aagaagttgc acttcttaac aaacaacgtg cgcgtcttga
    41221 aaaattcttg ggtggtatcg aagatatgcc tcgtatccca gatgtgatgt acgtagttga
    41281 cccacataaa gagcaaatcg ctgttaaaga agctaaaaaa ttgggaatcc cagttgtagc
    41341 gatggttgac accaatactg atccagatga tatcgatgta atcatcccag ctaacgatga
    41401 cgctatccgt gctgttaaat tgattacagc taaattggct gacgctatta tcgaaggacg
    41461 tcaaggtgag gatgcagtag cagttgaagc agaatttgca gcttcagaaa ctcaagcaga
    41521 ttcaattgaa gaaatcgttg aagttgtaga aggtgacaac gcttaattta tacaaatagt
    41581 aattacctag gagggcgggg cttagcccgg ctctcctatt ttcaaaaaat ataggagaat
    41641 taaaatggca gaaattacag ctaaacttgt aaaagagttg cgtgaaaaat ctggtgccgg
    41701 tgttatggac gctaaaaaag cgcttgtaga aacagacggt gacatcgaaa aagcgattga
    41761 attgcttcgt gaaaaaggta tggctaaggc agctaagaaa gctgaccgtg ttgctgcaga
    41821 aggtttgact ggtgtttatg ttaacggtaa tgttgcagca gttattgaag taaacgctga
    41881 aactgacttc gttgcaaaaa acgctcaatt cgttgaattg gtaaatacta cagctaaagt
    41941 cattgctgaa ggaaaacctg ctaacaacga agaagctctt gctttgataa tgccttcagg
    42001 tgaaactctt gaagctgcat acgtatctgc aacagcaact atcggagaga aaatctcatt
    42061 ccgtcgcttt gcattgattg aaaaaacaga cgcacaacac tttggagcat accaacataa
    42121 cggtggacgt atcggtgtta tttcagttgt tgaaggtgga gacgaagcac ttgctaaaca
    42181 attgtcaatg cacatcgcag cgatgaaacc aacagttctt tcttacaaag aattggatga
    42241 gcaattcgtt aaagatgagt tggcacaatt gaatcacgtt atcgaccaag acaacgaaag
    42301 ccgtgcaatg gttaataaac cagctcttcc acacttgaag tatggatcaa aagctcaatt
    42361 aactgatgat gttattgctc aagctgaagc tgacatcaaa gctgaattgg ctgcagaagg
    42421 caaaccagaa aaaatctggg acaaaattat tccaggtaaa atggatcgct tcatgcttga
    42481 taacactaaa gttgaccaag cttacacact tcttgcacaa gtttacatca tggatgacag
    42541 caagacagtt gaagcatacc ttgaatcagt taacgcttcg gtagttgagt ttgctcgctt
    42601 tgaagttggt gaaggtatcg agaaagctgc aaacgacttc gaagctgaag ttgcagctac
    42661 aatggcagca gccttgaata actaataata gaaaggaagc aaattgcttc cttttttgta
    42721 tagggcttag atttttcctg aaattgtttt ttccccagtc tcactcgatt agaataatta
    42781 aaacaaaaag ccctataata agggctaagg gcatttagga gactatactt caaattcata
    42841 gtaagcgcgt cataacaagg tatctatcct aattccccaa cttccagtat actagataaa
    42901 aaataattat cggaggaaag gtattgtact atgataattc aactaagtga tttaggtcaa
    42961 gttcaccttg tttgtggcaa gacagatatg aggcagggaa tagactcatt agcctatgta
    43021 gtt
//
LOCUS       DBEJJE010000014        42904 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEJJE010000014 DBEJJE010000000
VERSION     DBEJJE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.14"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            308..1753
                     /gene="cps4A"
                     /locus_tag="ACL3F5_000754"
     CDS             308..1753
                     /gene="cps4A"
                     /locus_tag="ACL3F5_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR0514594.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1755..2486
                     /gene="cps4B"
                     /locus_tag="ACL3F5_000755"
     CDS             1755..2486
                     /gene="cps4B"
                     /locus_tag="ACL3F5_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0514595.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2495..3187
                     /gene="cpsC"
                     /locus_tag="ACL3F5_000756"
     CDS             2495..3187
                     /gene="cpsC"
                     /locus_tag="ACL3F5_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR0514596.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3197..3886
                     /locus_tag="ACL3F5_000757"
     CDS             3197..3886
                     /locus_tag="ACL3F5_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR0514597.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3902..5269
                     /locus_tag="ACL3F5_000758"
     CDS             3902..5269
                     /locus_tag="ACL3F5_000758"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0514598.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5300..6472
                     /gene="cps2T"
                     /locus_tag="ACL3F5_000759"
                     /gene_synonym="wchF"
     CDS             5300..6472
                     /gene="cps2T"
                     /locus_tag="ACL3F5_000759"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGR0514599.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6469..7752
                     /locus_tag="ACL3F5_000760"
     CDS             6469..7752
                     /locus_tag="ACL3F5_000760"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0514600.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7715..8419
                     /locus_tag="ACL3F5_000761"
     CDS             7715..8419
                     /locus_tag="ACL3F5_000761"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGR0514601.1"
                     /translation="MKGLQMIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSR
                     GLLRGIGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVK
                     IGDYSQIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAEN
                     HSYEVLHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPD
                     NVIIGGVPAKILMERK"
     gene            8463..9698
                     /locus_tag="ACL3F5_000762"
     CDS             8463..9698
                     /locus_tag="ACL3F5_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0514602.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9706..10830
                     /locus_tag="ACL3F5_000763"
     CDS             9706..10830
                     /locus_tag="ACL3F5_000763"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0514603.1"
                     /translation="MKKVLIVRSGPYQVNPEGYNLQELGLASAISQQGYQCDVMYYHK
                     TKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKFLNQYDKIIISEYSQIMAVL
                     LSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKRTKTVFCKTEKAECYLKNKG
                     FNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNILYVGSLSKRKNTAQLIRIF
                     NILKSKSGKKSELQLVLIGKDEDNIVEKINYSRFKDDIIYQPYLKNSQLQFIYPSSQL
                     LVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDGINGKIVNDFNDEHWVDCIE
                     NLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDER"
     gene            10839..11681
                     /locus_tag="ACL3F5_000764"
     CDS             10839..11681
                     /locus_tag="ACL3F5_000764"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0514604.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            11723..12991
                     /locus_tag="ACL3F5_000765"
     CDS             11723..12991
                     /locus_tag="ACL3F5_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGR0514605.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            12984..13991
                     /locus_tag="ACL3F5_000766"
     CDS             12984..13991
                     /locus_tag="ACL3F5_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514606.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            13996..15438
                     /locus_tag="ACL3F5_000767"
     CDS             13996..15438
                     /locus_tag="ACL3F5_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGR0514607.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            15441..16541
                     /gene="glf"
                     /locus_tag="ACL3F5_000768"
     CDS             15441..16541
                     /gene="glf"
                     /locus_tag="ACL3F5_000768"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HGR0514608.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            16568..17437
                     /gene="rfbA"
                     /locus_tag="ACL3F5_000769"
     CDS             16568..17437
                     /gene="rfbA"
                     /locus_tag="ACL3F5_000769"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGR0514609.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17438..18031
                     /locus_tag="ACL3F5_000770"
     CDS             17438..18031
                     /locus_tag="ACL3F5_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGR0514610.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            18044..19093
                     /gene="rfbB"
                     /locus_tag="ACL3F5_000771"
     CDS             18044..19093
                     /gene="rfbB"
                     /locus_tag="ACL3F5_000771"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGR0514611.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            19159..20010
                     /gene="rfbD"
                     /locus_tag="ACL3F5_000772"
     CDS             19159..20010
                     /gene="rfbD"
                     /locus_tag="ACL3F5_000772"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGR0514612.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            20107..21259
                     /locus_tag="ACL3F5_000773"
                     /pseudo
     CDS             20107..21259
                     /locus_tag="ACL3F5_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013641878.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21458..23440
                     /locus_tag="ACL3F5_000774"
     CDS             21458..23440
                     /locus_tag="ACL3F5_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0514613.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            23742..29045
                     /locus_tag="ACL3F5_000775"
     CDS             23742..29045
                     /locus_tag="ACL3F5_000775"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0514614.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDESKLLSSISF
                     LGNALVSVSSNQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTAESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(29212..31371)
                     /gene="pbp1a"
                     /locus_tag="ACL3F5_000776"
     CDS             complement(29212..31371)
                     /gene="pbp1a"
                     /locus_tag="ACL3F5_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0514615.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(31368..31964)
                     /gene="recU"
                     /locus_tag="ACL3F5_000777"
     CDS             complement(31368..31964)
                     /gene="recU"
                     /locus_tag="ACL3F5_000777"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0514616.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            32030..32557
                     /locus_tag="ACL3F5_000778"
     CDS             32030..32557
                     /locus_tag="ACL3F5_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0514617.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            32627..32956
                     /gene="gpsB"
                     /locus_tag="ACL3F5_000779"
     CDS             32627..32956
                     /gene="gpsB"
                     /locus_tag="ACL3F5_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0514618.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            32977..33357
                     /gene="rnpB"
                     /locus_tag="ACL3F5_000780"
     ncRNA           32977..33357
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3F5_000780"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            33442..34599
                     /locus_tag="ACL3F5_000781"
     CDS             33442..34599
                     /locus_tag="ACL3F5_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0514619.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            34612..36006
                     /gene="mapZ"
                     /locus_tag="ACL3F5_000782"
     CDS             34612..36006
                     /gene="mapZ"
                     /locus_tag="ACL3F5_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0514620.1"
                     /translation="MSKKRRNRHKKEAQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            36082..37506
                     /gene="gndA"
                     /locus_tag="ACL3F5_000783"
     CDS             36082..37506
                     /gene="gndA"
                     /locus_tag="ACL3F5_000783"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0514621.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            37518..38207
                     /locus_tag="ACL3F5_000784"
     CDS             37518..38207
                     /locus_tag="ACL3F5_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0514622.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELKVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            38306..39208
                     /locus_tag="ACL3F5_000785"
     CDS             38306..39208
                     /locus_tag="ACL3F5_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0514623.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATSTVFADTMGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKKTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPATGIM
                     QTGWQFLGNRWYYLRSSGAMATGWYQDGSTWYYLDPSNGDMKIGWTKVNGNWYYLNSS
                     GAMVTGSQTIDGKVYNFASSGEWI"
     gene            39226..40224
                     /gene="cbpJ"
                     /locus_tag="ACL3F5_000786"
     CDS             39226..40224
                     /gene="cbpJ"
                     /locus_tag="ACL3F5_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGR0514624.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGKWYYAYGSGALAVNTTVDGYSVNYNGDWVR"
     gene            complement(40343..41575)
                     /locus_tag="ACL3F5_000787"
     CDS             complement(40343..41575)
                     /locus_tag="ACL3F5_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0514625.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEVVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILYQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(41618..42205)
                     /locus_tag="ACL3F5_000788"
     CDS             complement(41618..42205)
                     /locus_tag="ACL3F5_000788"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0514626.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            complement(42105..42443)
                     /locus_tag="ACL3F5_000789"
                     /pseudo
     CDS             complement(42105..42443)
                     /locus_tag="ACL3F5_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT        13674 a         7141 c         9314 g        12775 t
ORIGIN      
        1 ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa
       61 gattatacca cattgtgtac tatattatat tgaaactaga atagtacaca tctgcttcta
      121 aaatattgtt agaaaacgat ttgactgtcc tgatcaattt gtcatgttct tatttcattt
      181 tactatattt ttggttcgcg ggaagtctac taagatactt aaagatgcag atagtgaaaa
      241 taaaggtgta gacattaccg taaaaaagtg atataatcgt atgatgttca atgtataggt
      301 gttaatcatg agtagacgtt ttaaaaaatc aagttcacag aaagtgaagc gaagtgttaa
      361 tatagttttg ctgactattt atttattgtt agtttgtttt ttattattct taatctttaa
      421 gtacaatatc cttgctttta gatatcttaa tctagtggta actgcgttag tcctactagt
      481 tgccttggta gggctactct tgattatcta taaaaaagct gaaaaattta ctatttttct
      541 gttggtgttc tctatccttg tcagctctgt gtcgctcttt gcagtacagc agtttgttgg
      601 actgaccaat cgtttaaatg cgacttctaa ttactcagaa tattcaatca gtgtcgctgt
      661 tttagcagat agtgagatcg aaaatgttac gcaactgacg agtgtgacag caccgactgg
      721 gactgataat gaaaatattc aaaaactact agctgatatc aagtcaagtc agaataccga
      781 tttgacgatc gaccagagtt cgtcttactt ggcagcttat aagagtttga ttgcagggga
      841 gactaaggcc attgtcttaa atagtgtctt tgaaaatatc atcgagtcag agtatccaga
      901 ctatgcatcg aagataaaaa agatttatac caagggattc actaaaaaag tagaagctcc
      961 taagacgtct aagaatcagt ctttcaatat ctatgttagt ggaattgaca cctatggccc
     1021 tattagttcg gtgtcgcgat cagatgtcaa tatcctgatg actgtcaatc gagataccaa
     1081 gaaaatcctc ttgaccacaa cgccacgtga tgcctatgta ccaatcgcag atggtggaaa
     1141 taatcaaaaa gataaattaa cccatgcggg catttatgga gttgattcgt ccattcacac
     1201 cttagaaaat ctctatggag tggatatcaa ttactatgtg cgattgaact tcacttcttt
     1261 cttgaaaatg attgacttat tgggaggggt agatgttcat aatgatcaag agttttcagc
     1321 tctacatggg aagttccatt tcccagtagg gaatgtccat ctagactctg agcaggctct
     1381 aggttttgta cgtgaacgct actcactagc cgatggagac cgtgaccgtg gtcgcaacca
     1441 acaaaaggtg attgtggcta tccttcaaaa attaacgtca accgaagcac tgaaaaatta
     1501 tagtacgatc attaatagct tgcaagattc tatccaaaca aatatgccac ttgagactat
     1561 gataaatttg gtcaatgctc agttagaaag tggagggaat tataaagtaa attctcaaga
     1621 tttaaaaggg acaggtcgga cggatcttcc ttcttatgca atgccagaca gtaacctcta
     1681 tgtgttggaa atagatgata gtagtttagc tgtagttaaa gcagctatac aggatgtgat
     1741 ggagggtaga tgaaatgata gacatccatt cgcatatcgt ttttgatgta gatgacggtc
     1801 ccaagtcaag agaggaaagc aaggctctct tggcagaatc ctacaggcaa ggggtacgaa
     1861 tcattgtctc tacctctcac cgtcgcaagg gcatgtttga aactccggaa gagaagatag
     1921 cagaaaactt tcttcaggtt cgggaaatag ctaaggaagt ggcgagtgac ttggtcattg
     1981 cttacggagc tgaaatttac tacacaccag atgttctgga taagctggaa aaaaagcgga
     2041 ttccgaccct caatgatagt cgttatgcct tgatagagtt tagtatgaac actccttatc
     2101 gcgatattca tagcgccttg agcaagatct tgatgttggg aattactcca gtcattgccc
     2161 acattgagcg ctatgatgct cttgaaaata atgaaaaacg cgttcgagaa ctgatcgata
     2221 tgggctgtta cacgcaagta aatagttcac atgtcctcaa acccaaactt tttggcgaac
     2281 gttataaatt catgaaaaaa agagctcagt attttttaga gcaggatttg gttcatgtca
     2341 ttgcaagtga tatgcacaat ctagacggta gacctcctca tatggcagaa gcatatgacc
     2401 ttgttaccca aaaatacgga gaagcgaagg ctcaggaact ttttatagac aatcctcgaa
     2461 aaattgtaat ggatcaacta atttaggaga aatgatgaaa gaacaaaaca cgatagaaat
     2521 cgatgtattt caattattta aaaccttgtg gaaacgcaag ctaatgattt taatagtggc
     2581 acttgtgaca ggtgcggggg cttttgcata tagcactttt attgttaagc cagaatatac
     2641 gagtaccacg cgaatttacg tagtgaatcg cgatcaagga gacaagccgg ggctgacaaa
     2701 tcaggatttg caggcaggat cttatctggt aaaagactac cgtgagatta tcctttcgca
     2761 gaatgtattg gaaaaagtag cgacaaattt gaagttggat atgccaacaa aaacgttagc
     2821 cagcaaagtt aaagtgactg taccaactga cactcgtatc gtctcaatct ctgtcaaaga
     2881 taaacaacca gaagaagcca gtcgtatcgc taattctcta cgagaagttg ctgcagaaaa
     2941 gatcgtcgct gtaacgcgag tatctgatgt aacgacactt gaagaagcgc gaccagctac
     3001 gactccctct tctccaaatg ttcgacgcaa ttccttgttt ggttttcttg gaggagcagt
     3061 cgtaacagta attgctgttc ttttgattga gttgctcgac acccgtgtga aacgtcctga
     3121 agatgtcgaa gatgtactgc aaattccact tttaggggtc gttccagatt tgaacaaaat
     3181 gaaataggag gaagttatgc caacattaga aatctcacag gcaaaattgg attttgtaaa
     3241 aaaggcagag gaatattata acgctttgtg cacgaaccta cagttaagtg gagatgattt
     3301 gaaagtattt tctatcactt ctgtgaaact aggagaagga aaatcaacga cttccaccaa
     3361 tatcgcttgg gcttttgcgc atgcaggtta caaaacgctg ctgattgatg gagatattcg
     3421 caattctgtt atgttaggtg tctttaaagc aagggataag attacaggcc tgacagaatt
     3481 tttatcagga actacagacc tatcacaagg gctttgtgat accaatgtcg aaaatctctt
     3541 tgtaattcag gctggctctg tgtcaccgaa tccgacagct cttcttcaaa gtaagaattt
     3601 cagtacaatg cttgaaacct tgcgtaaata ttttgactac atcattgtag atactgctcc
     3661 tgtcggtgtc gtgattgatg cggctattat tacgcgaaaa tgcgatgctt ctattttagt
     3721 gacggaggta ggtgaaataa atcgacggga tattcaaaaa gcaaaagaac agttggaaca
     3781 cacaggaaag ccgtttttgg gagttgtgtt gaataaattc gatacttcag tagacaaata
     3841 cggttcttat ggaaattatg gagattacgg gaaaaataaa aaataggtcg ggggattaga
     3901 gatgaatgga aaaatagtaa agtcttcatt ggccataatc cagagttttc ttgttatttt
     3961 attgacttat ctacttagtg ctgtgagaga agcggagatt gtttcaacaa cagctattgc
     4021 actttatatc ctccattatt ttgtctttta tatcagtgat tatggacagg atttctttaa
     4081 aagaggatat ttgattgaac ttgtccagac attgaaatat atcctattct ttgcactagc
     4141 gattagtatt tctaattttt tcttagagga tcgatttagt atttccagac gaggcatgat
     4201 ttacttcctc acattacatg ctctcttagt ctatgtgcta aacctattta tcaagtggta
     4261 ttggaagcgg gcttatccca actttaaagg aagtaagaag attctcctac ttacagcaac
     4321 ttctcgtgtc gaaaaggtac tggatagatt aatagaatca aatgaggttg ttggggagtt
     4381 ggtagccgtc agtgtcttag ataaaccaga ttttcagcat gattgtttaa aggtagtagc
     4441 agagggggag atagtaaact ttgcgactca tgaggtggtc gatgaagtct ttatcaatct
     4501 tccaagtgaa aaatacaata ttggagagct tgtctctcag tttgaaacga tgggaattga
     4561 tgtaacagtt aatctaaatg cttttgatcg tagtttggca cgtaacaagc aaattcgtga
     4621 gatggcagga ttaaacgttg tgactttttc tacaacattt tataagacta gtcatgtaat
     4681 tgctaagcgg attattgata tcatgggtgc attggtaggg ctgatactat gtggtttagt
     4741 cagtattgta ctggttcctt tgattcgaaa ggatgggggc tctgctattt ttgctcagac
     4801 gcgtatagga aaaaatggtc gtcagttcac tttttataag tttcgctcta tgtgtgtaga
     4861 tgccgaggcg aaaaaaagag aactcatgga acaaaatacc atgcagggtg gaatgtttaa
     4921 ggtggacgat gatcctcgta tcacgaaaat tggttgtttt atacggaaga ctagcttgga
     4981 cgagctacca cagttttata atgttctaaa gggagatatg agtttggttg gcacacggcc
     5041 accaacagtg gacgagtatg agcactatac cccagaacaa aagcgtcgtc tgagttttaa
     5101 acctggcata acagggttat ggcaggtcag cggacgaagt gagattaaga attttgatga
     5161 agttgtcaaa ttagatgtag cctatataga cgattggaca atttggaaag atattgaaat
     5221 tttattgaag acagttaaag ttgtattgat gaaggatgga gcgaagtgat ttttgccctt
     5281 cggtcttgtt aggagagata tgaaacagtc agtttatatc attggttcaa aggggattcc
     5341 tgccaagtat ggaggatttg aaacctttgt tgagaaatta acagaatatc aaaaagatgg
     5401 taacatccaa tactatgttg cttgcatgcg cgaaaattct gcaaagtcag gatttacagc
     5461 agacacattt gagtacaacg gtgctatttg ttacaacatt gatgtgccta atattggtcc
     5521 tgctagagcc attgcttacg atattgcagc ggtcaataag gctattgaat tgtctaaggg
     5581 aaacaaggac gaggctccca ttttttacat tctagcttgt cgtatcggac cttttatttc
     5641 tggacttaag aaaaaaattc gttcgatcgg aggccgtttg ctggtaaatc cagatggtca
     5701 tgagtggctt cgagctaaat ggagcttgcc agttcggaag tattggaaat tttcggaaca
     5761 gttgatggtc aaacatgcag atttattagt ctgcgatagc aaaaatatcg aaaaatatat
     5821 tcgagaggac tataaacagt atcagcccaa gacgacctat atcgcttatg gtacagatac
     5881 taccccttca agtctgaaat cagaagatgc caaagttcga aactggtatc gtgaaaaggg
     5941 agtaagcgaa aatggctatt atctagtggt gggacgattc gttcccgaaa acaactatga
     6001 aaccatgatt cgtgaattta tcaagtctaa gtccaataag gactttgtcc ttattacaaa
     6061 tgtggaacag aataaatttt acgatcagtt gctcaaggaa acaggtttcg acaaggatct
     6121 aagagtcaaa tttgtgggaa cagtctatga ccaagaattg ctcaagtata tccgtgaaaa
     6181 tgctttcgcc tatttccatg gacatgaagt tgggggtacc aatccatcgc ttcttgaagc
     6241 tttagcatcc actaaactca acttgttgtt ggatgtcggc tttaaccgtg aagttggtga
     6301 agacggagcc atttattgga aaaaagatga gctagcgcat gtaatcgaag aagtggaacg
     6361 atttgatgaa ggtgatatta cggaattaga cgaaaagtct agccaacgaa ttgcggatgc
     6421 atttacgtgg gaaaagattg tgtcagatta tgaggaagtg tttactgtat gaaaattttg
     6481 cattatactt taggctttca accatcacgt acaggtggtc ttgtcaagta tgctgaggat
     6541 ttgatgactc aacaagctac agatggacat gaagtaatcg cattatatcc aggagaaatc
     6601 tcaattatat ttaggcaggt tagaataaaa aaagcagaga atcgaaaatt ccaatgctat
     6661 aaaataataa acagcctacc cttggctcta tttggtggta tttcagaacc agatgaattt
     6721 atgaagagtt gtgataaagc ttcttatagg aaatttttga aaaatattaa ggtagatgta
     6781 attcacattc actcgcttat aggattacat aaggaattta ttgaagttgc aaaagaatta
     6841 ggaattaaaa ctgtatttac aagccatgat tattatggtt tagcgccagt tccgcatttt
     6901 tattttaacg gagtagatta tagtagtaat aatactaatt tagcatggaa catcatgtcc
     6961 tctaatgctc ttagtgtaaa aaaacttcga ttctttcaag tctcttttta cccaacaatt
     7021 cggaaattga tgaaaatgct tgggaaaaat ccaaagtcca agaaaaactt agtaattcgt
     7081 gatatcacgg aggctattga ttatagtgct ctccgctctt attataaagc aatgtttggg
     7141 ttaatagatg cttacctttt caatagtcag ttagctaagg aagtttatga agctaatcat
     7201 ataataccta aaaacaatat catagtgtcc atttctaaca gctcaataag taatcataat
     7261 attcgtgtta gttccggtga gaaaacagtg gtagcttata ttgggcctga tgaggaatat
     7321 aaggggtatt ttgattttct agatatagtt aatgatttag atcaggaaaa gtatgatatt
     7381 aaaacatatg gacattttcc aaatgaagat tgtccacctt atatccaaca gaacggttat
     7441 ttcacaaaag acacggttgg aagcgtttat tccaatatag atattttgat tgtgccgagt
     7501 aggtggaagg aaacatttgg tttgattagt atagaggcgc tatcgtatga tgtgaatgtt
     7561 tttgtgagca aaaatgtggg ctctaaagat ttggtttcag aagaacatat ctttcataat
     7621 aaagacgatt tgttaaaaaa aattcaatat gtaaaattcg agaatgtaaa attcaaaacg
     7681 atgaaagagc atatggtgga gattataaat tactatgaaa ggattacaaa tgataatcaa
     7741 aagattaatt aagacaatta caggtaaaga aattgatctt caccctgata tcccaataac
     7801 ttacattctt cagagaggtt ttcaatacgg tttgggtctt agtcgagggt tgttacgtgg
     7861 tattggtcta ggaaaaaaag gcaaacgatt atttattgga cgtggggtaa cccttctcgc
     7921 aaaacgcaag ttatatgttg gaaacaatat ccgaatcggc aaatatgtga gcatagattg
     7981 cctttcaaag gatgggatcc aaattgcgga taatgttaag ataggagatt actcgcaaat
     8041 aattggtaca ggttcagtaa aaaatatggg tattgggctc aaaattggaa agaactcttc
     8101 tttctcagaa tatagtttat tcggttctgc aggtgggatt actatcggag gagatgttat
     8161 tgctggacaa aatgtacgtt ttcatgctga gaatcatagc tacgaagtgt tgcatatacc
     8221 aatcagagag caaggtgtta atcgtaaagg gatatccgtt ggtgacaatt gctggattgg
     8281 ggcaggagct gtttttttag atggatctag tatcggttca ggttgtatcg ttgcaacgaa
     8341 tgcggttgtt actaagaaat ttccagataa tgtaattatt ggtggagtgc cagctaaaat
     8401 tttaatggaa agaaagtagt attaaattaa ttgtataaat ggagggaaat gatatgtcta
     8461 aaatgaagat tgctgtagtt gggacaggtt atgttggttt atccatttct gtgttacttg
     8521 cacaacacca tcatgtagta gcagtagata ttgtaaaaga gaaagtagaa ttaattaata
     8581 aaagaatttc acctattcag gatgatttta ttgaaagata tctttcagaa agtaatttag
     8641 atttagttgc aacaatagac gctgaaacag cttataaaga tgcctctttt atcgtagtag
     8701 cgacaccaac aaattatgac ttagaaagaa atttttttga tacatcaaca gttgaatcgg
     8761 tcattcaaca agttcagaat atgaattcta cagcaactat agtaataaaa tcaacagtcc
     8821 ccgtgggctt taccgattca attcgtaaaa aattaggaat ttcaaatctt ctattcagtc
     8881 ctgaattttt gcgtgaatca agggcacttt atgataactt atatccaagt cggatcatag
     8941 ttggaacaga tttaagtaat caaaaattag ttgaaaaagc ccaagttttc tctaatcttt
     9001 tagtgcaagg tgccattaaa aaagatatcc ctattttaac tatgggattt actgaagctg
     9061 aagcagttaa attatttgct aatacctact tagcattgcg ggtatcatat tttaatgaat
     9121 tagatactta tgcagagatc aaagggttag atactcaaaa aataattgaa ggtgttagtt
     9181 tagatcctcg tatcggaacc cattataata atccgagctt tgggtatggt ggatattgct
     9241 taccaaagga tactaagcaa cttttagcca attataagaa tgtcccagaa gagcttattg
     9301 gagctatagt acgaagcaat acaacacgta aagattttat tgctaatcaa gttcttaaag
     9361 tggtgaatta taatatacca gaagacgata ttcctactaa acagatggag aaagaagttg
     9421 ttattggaat ataccgatta actatgaaaa gtaacagtga taactttcgt cagagttcaa
     9481 tacaaggagt tatgaaacgt attaaggata gaggagttaa agtaatcatt tttgagccta
     9541 ctctaaaaga tagtgataca ttctttggaa acgctgttat aaatgattta gaagagttca
     9601 aagtaaagtg tgatgtgatt attgcaaatc gttatgatga aacgttgaat gacgttaagg
     9661 ataaagtata tacacgagat atttttagaa gagattgata aaaatatgaa aaaagtatta
     9721 attgttcgaa gtggacctta ccaagtcaat ccggaaggat ataatcttca agaacttggt
     9781 ttagcctccg ctatcagtca gcaaggctac cagtgtgatg tcatgtatta tcacaaaaca
     9841 aagaactatg atcaattata tgagaaaaat ggggaacaaa ttaaaatatt ctggaggagg
     9901 ggaataagat tatttagaag tggaatttat ccccagattt taagagagaa atttttgaat
     9961 cagtatgata agataattat ttctgagtac agccagatta tggcagtttt attgtctaga
    10021 attcattcca atgtatatat ttataatggc ccatactata atctatttaa gattcccatt
    10081 attgaaccta tatacgattt tctttttgta gaaatgctca ataagagaac caaaacagtt
    10141 ttctgcaaga cagaaaaagc agagtgttat cttaaaaaca aaggattcaa tgattgtaaa
    10201 gtagtgggcg taggtctaga tattgagaag tttgaacaag aagaggaacc tacagaggat
    10261 actatagagc ttttaagaag aatggagaat aaacaaaata ttctttatgt aggttcacta
    10321 tcaaaaagaa aaaacacagc tcagttaatt agaattttta atattttaaa atctaaaagt
    10381 ggtaagaaaa gtgaacttca attggtattg attggtaagg atgaggataa tattgttgaa
    10441 aaaattaact attcacggtt taaagatgat attatttatc aaccttattt aaagaattct
    10501 cagcttcaat ttatttaccc atcatcacaa ctacttgtgc tcccgtcagt tcaagagatt
    10561 tttggtatgg tattacttga ggcaatgtat tttaagttgc ctgttgtttc cagtgcaagt
    10621 gctggaggag agacactgat tcaagatggt ataaacggta aaattgtgaa tgattttaat
    10681 gatgaacact gggtggattg tatagaaaat ctattaaata acccattgga attgaaacgg
    10741 cttggagaat gtgctcataa gcgcattacg gaacagttta tgtggtcttc aattgcgaga
    10801 aaaataattg agacatttga tgaaaggtaa gacttgctat gaatttttgt tttgtgattt
    10861 tgcattatcg taccagcaat gacactatag agtgtatcaa atcgattcaa aagcttgagg
    10921 gagattataa aattgtaatt gttgataatg cttctcaaaa tggcagtata gaaagggtag
    10981 aagccttatt tgcaaataat gacgagatag ttataataaa aaacacgaaa aacttaggat
    11041 ttgctgctgg aaataatatt ggatacgcct acgctaggac tcaaataaaa gctgatatga
    11101 ttgctgtact taataatgat attgttatta agcaaaaaga tttcatcaat cgtatatttg
    11161 aactctatag aaattctcag tttcatatcg ctggtccaga cattgtctct cttgtagatg
    11221 gtcatcatca aagtcctgtt gttgagaaga ttaattctat atctaaggct aataaagaac
    11281 tttttaaata tagaatcttg aggattatta ataaaatagg attatatgag ctgatgacta
    11341 gacagccaaa aaaagaatta aatagaataa gtgttgcaga ccctatgaga tatcaggaaa
    11401 atgttatttt acatgggagt tttgtaattt tttcaccgtt gtatgtttca gaggaggagt
    11461 gtgctttcag accggataca ttcatgtata tggaagagcc tattctatat gaatattgca
    11521 tgcttaaaaa ttataagaca gtatttgatc cttctattgt aatttatcat aaagaggact
    11581 catcaacaaa ttcgttgtat aatgcagcat atgcaaaaag agagtttgtt tttaaaaata
    11641 tgattagatc tctaaagatt tatagaagtc tattgaagta gtaaactaag gaaaggataa
    11701 taattagaaa ttgaatctta gtatgttagc cttgacaata ggaacagtgg tatttgttaa
    11761 aaaaacgtat aggacgtttc tcaatcccat aattttattt gtaattttgt ggtttattat
    11821 aacaactttg tcaagtttaa aactattcca acttttcgag attagtactc acacacaaca
    11881 aattattttg cttgggactt ctctatttgt tataggggga gggatagcaa tttggtttcg
    11941 ggataaattt tattttaaag ttggcggtaa ctcatatttt acaacagact ttgaaattaa
    12001 ttataatttg ttctttttgc taggtatcat ttgccttttc tattatttgc cagatttctt
    12061 ttcctcactg gtatcattaa taagaggtgg gaatttaaac ttagttagac aatctgcgca
    12121 ggatgcagta gataccagtg gattaaagaa tttcattgga acatttattg ttagtcctag
    12181 tgccatggta ttagaaatat taggagtatt agatttctgg agcaataaaa aaggtagaaa
    12241 actattttat cttagtttag ctgtcatttt tgtaagagtt attgcagatg ctggtagaac
    12301 acctctattt aatgttgtca tatatttatt acttactgtt ttagcaaata ggttctctga
    12361 aaaaactgaa aagaagagaa aagttagtaa aattaagata gtaaattatg gtatgctagg
    12421 ttcaattatc ttatggctat caactttatc taggacaaca acctccgttt ataggattct
    12481 ttatttttat ttcgcaatgt ccccaatatt attagaaaag tggagtagtg tacttgattc
    12541 tgaaaaatta gtaacaaagg gtttggtttc gttgaacggt ttcttttttt caatctcata
    12601 tgtacttaaa aatctgttta gaatagatta ttcgcaaaga gtattagaag catacacaat
    12661 gattgcgaat actgatgcaa tctggtataa tattgcacct ggtttgacca aggcaaatgc
    12721 atatgtctct ctgttttggt tcttttatgc ggatggacgt ttactaggag ttttaatagg
    12781 atcccttcta tatggtacct tttgtggtta tatcttttgc aggtatatcc agcaacaaaa
    12841 taaaaagaat ttggctatgt tactatttat ttatcaaggt gtttttttct cttttattag
    12901 atttccgttt tcaaaatcaa attatgcaat tgcattcgta ctcttattat tttttgcttt
    12961 taagaagaaa ggaatagaga aaagtgttta atatcaatga ccagtctatt atttatgttg
    13021 catgtcctta ttttaataaa acaggtggaa cggagcttgt ccatcaatta gtttattcta
    13081 ttaatcattt tggggggaaa gctatcgttg cttattatgg tagtgaaagt gctccaaata
    13141 aggtgaatcc tgcgtttaga gaatatgttt ctacgtttgt tgatataaaa gatgttattg
    13201 actctcttga taatattatt attttaccgg aaattaatcc ggatttagct gctaatctag
    13261 agtctattca aaaagcagta tggtggatga gcgttgacaa ttatttgaag cgtaatggta
    13321 ttttaggttc cttggaacat tttggacttt tacgaacaat taaattattt gtaaaaggaa
    13381 atattaaaat aggtggatat agaatagata aagagattcc ccatctttat caaagtgaat
    13441 acgccaagca atttcttcta gctaaaggtg tcaaaaagta ctatagattg tctgattatt
    13501 taaacgagtc ttatattcag cgatctattt caacagacac taaaaaagat gttattcttt
    13561 acaatcctaa aaaagggatt gaatttactc gtgagctaat taaacaggct ccagaattaa
    13621 cgttctctcc aattgagaat atgtcaactg aacaggtgaa aaaattactt tcaaaaagca
    13681 aagtatatat tgattttggc aaccatcctg ggaaagatag attcccacgg gaggcagcga
    13741 tatcaggttg ttgtgtgata actgggaaac gaggttctgc aaaatattat aaggatattc
    13801 ctattccaga ttcatacaaa tttgaagaca ctgttgaaaa tatccccaac attattgaga
    13861 ccctgaaatc atgcttaaaa aattatgaca aacatactgt tgactttgag aaatatcaac
    13921 aatatattaa atctgaacat gatttatttg aaagagatgt gaaagaatta ttcactagga
    13981 ataggggtta aggttatgtc aaccagaaat tcacttatta aaaattctct ttataatgtt
    14041 gcttatagaa tgttaaatat catatttcca ttagtatccg caacatatac tgcacggata
    14101 attttagcta gtggagttgg ggaggtctcg tttgcacaaa atgttgtttc ttactttaca
    14161 acgatagctg ctatgggtat tccaaattat ggtatacgag aaattgctaa aactagaaat
    14221 aaagcagagg ctacgaataa agttttttca gagctatttc tgattaatgg attgtctaca
    14281 ttactgtgtt ctatagtata tttaattctg attttgacat tcaatagcat ttttgataat
    14341 acatcaatgt atcttgctgt gggtttaaca ttagtgttta acttccttaa tatcgattgg
    14401 ttctatcaag gaaaagagga ctatgcatac atcacgaaac gtagtttcag tataaaactt
    14461 atttctcttt ttagtttatt tatttttgtt agagatactg acgatgcagt taactatgca
    14521 ttgatttcta gcttagcaat tggcgggaat aatattttta atcttgttaa tttaaggaaa
    14581 tataatatta gatttagttt taataatatt aagattagaa gacacttaaa acctattttt
    14641 gttttgttgg gttcagtgat tgctattgaa atctatacta tgctggatac cactatgatt
    14701 ggtgctatgg taggaacgac tgaggtaggt tattatacaa attctatgaa gctagttaaa
    14761 ttgctgataa ctgtgattac cgctattgga ggagtgcttt taccacgact aagtgattat
    14821 tattctaagg gagaatttga aaaattaaat cacatcgttg ataaagtttt tagaatcatg
    14881 ttgtttcttt ttttaccagc ccaagttgca ttaattctag ttgcaccagt aattatgccg
    14941 attttatttg gtgatagttt tataccagca gtgttaacac ttcaacttac ttctttgctt
    15001 atatgtacat tagggtttag taatttattt gggactcaaa tattactaac atttggagat
    15061 gagcgaaagc ttttgattag cacaatttta ggagcgctta gtaatatcgc tttgaaccta
    15121 attctgattc cagtaatggc tcaaaatgga gcagcgttgg catctgtgat tagtgaaaca
    15181 attgttactt taacagcata ctactatgcg aaaaaacgtg tgacaattag gtttgactta
    15241 ggattttatt tgccaactgt tgtttcaaca ataatcatgg gtggagctat atatgtagta
    15301 atgcaattgt atattgggga tatagaaaaa atgttatttt caactttgtt aggaggtgtt
    15361 gtattccttt taattaacgt ttttatgaag aatcctatta tatatgaatt tacaggtatt
    15421 ataaagagaa agagataatt atgtacgact atttaatcgt tggagcgggt ttgtctggag
    15481 caatcttcgc acacgaagct acaaagcgtg gaaaaaaagt aaaagtgatt gataaacgcg
    15541 atcacattgg agggaacata tactgtgaga atgtagaagg tatcaatgtt cataaatatg
    15601 gtgcccatat cttccatact tctaataaaa aagtctggga ctacgtcaat caatttgctg
    15661 agtttaacaa ctatatcaac tcacctgtcg caaactataa gggaagtctt tataaccttc
    15721 ctttcaatat gaataccttc tatgctatgt ggggcacaaa aactccacaa gaagtgaagg
    15781 ataagattgc tgagcagaca gctggtatga aggatgttga gccgaaaaat ctggaagaac
    15841 aagctatcaa gttgattggt ccggatatct atgaaaagtt gatcaagggt tatacagaaa
    15901 agcaatgggg acgctcagcg atagaacttc ctccatttat cataaaacgc cttccagttc
    15961 gtttaacctt tgataataac tattttaatg accgttacca agggattcct attggtggtt
    16021 acaatgtcat catcgaaaat atgctgaaag atgtagaagt tgaacttgga gtagactttt
    16081 ttgctcatcg tgaagagttg gaagcatctg ctaacaaagt tgtcttcaca ggaatgatcg
    16141 accaatattt tgactacaag cacggagagt tagaataccg tagccttcgt tttgagcatg
    16201 agattttaga cgaggaaaat tatcaaggga atgctgtagt gaactataca gagcgtgaga
    16261 tcccttatac tcgtatcatc gaacacaaac attttgaata tggaatgcag ccaaagacag
    16321 ttatcacgca tgaatatcca gctgactgga agcgtgggga cgagccctac tatcctatta
    16381 acgatgagaa aaataatgct atgtttgcta aataccaaga agaagcagcg cagaatgata
    16441 aagttatctt ttgtgggcgt ttagcagatt ataagtatta cgatatgcat gtggtgattg
    16501 aacgggcgct tgaggttgtg gagaaagaat ttagtaattg aaaaacaacg aagaaaggtt
    16561 gcttattatg aaaggtatta ttctagcagg tggttcggga actcgcttgt atcctttgac
    16621 tcgagccgca tcaaaacaac ttatgccggt ttatgataaa ccgatgattt actacccact
    16681 ttcaacatta atgttggctg ggattaggga tattttgatt atctcaactc ctcaagattt
    16741 gcctcgtttt aaagagcttc ttcaagatgg ttccgagttt ggtattaaac tttcttatgc
    16801 tgagcaacca agtccagatg gtttggcaca agcctttatc attggggaag agtttatttc
    16861 tgatgatagc gttgcgctaa tcttaggtga taatatctac catggttctg ggctttccaa
    16921 gatgctacaa aaggcagcga gtaaggagtc gggagcaact gtttttggct atcatgtcaa
    16981 ggatccagag cgctttggtg tggttgagtt tgatcaggat atgaaggcta tttctattga
    17041 agaaaagcca gagcaacctc gttcaaacta tgcagttaca ggtctctatt tctatgataa
    17101 tgatgtagta gagattgcca agagtattaa accaagtcct cgtggtgaac tggaaattac
    17161 agatgtaaac aaagcttacc tagatcgtgg tgatttgtct gttgagctta tgggacgtgg
    17221 ctttgcttgg ctggatactg gaactcatga aagtttacta gaggcttcac agtacatcga
    17281 aacagtccaa cggatgcaaa atgttcaggt agcaaactta gaagaaattg cctatcgcat
    17341 gggttatatc agtcgtgaag atgtattgac cttagctcaa ccacttaaga aaaatgaata
    17401 cggacagtat ctgctccgtt tgattggaga agcatagatg acagataatt ttttcggtaa
    17461 gacgcttgcg gcacgcaagg ttgaagctat tccaggcatg ttggagtttg atatccccgt
    17521 tcatggagat aatcgtggct ggtttaaaga aaatttccaa aaggaaaaaa tgcttccact
    17581 tggatttcca gagtctttct ttgcagaagg aaaattgcaa aacaatgtat ccttctcacg
    17641 taaaaatgtc cttcgagggc tccacgcaga gccttgggat aagtacatct ctgtagcaga
    17701 tggagggaaa gttctgggtt cttgggttga tctacgcgag ggtgaaacct ttgggaatac
    17761 ctatcagaca gtaattgatg caagcaaggg aatctttgtt cctcgaggcg tagctaatgg
    17821 cttccaagtt ctatcagata cagtgtcata tagctatctg gtcaatgatt actgggctct
    17881 cgagctcaaa cccaagtatg cctttgtgaa ctacgctgat ccaagccttg gtattgaatg
    17941 ggaaaatatt gcagaagcag aggtttcaga agcagataaa catcatcccc tacttaagga
    18001 tgtaaaacct ttgaaaaaag aagatttgta aaaaggaaag aatatgactg aatacaaaaa
    18061 tattatcgtg acaggtggag ctggctttat tggttctaac tttgtccatt atgtttacga
    18121 gaactttcca ggtgttcacg tgacagtcct agataagttg acttatgctg gaaatcgcgc
    18181 gaatattgag gaaattttag gtaatcgtgt tgagttagtt gttggtgaca ttgctgatgc
    18241 ggagttggta gacaagttgg ctgctcaagc agatgctatc gttcattatg cagcggaaag
    18301 ccacaatgat aattcgctca atgatccatc gccatttatt catactaact tcatcggaac
    18361 ctatactctt ttagaagctg ctcgtaagta tgatattcgc ttccaccatg tatcgacaga
    18421 tgaagtttat ggggatctcc ctttacgcga agatttgcca ggtcatggtg aaggaccagg
    18481 tgagaaattt actgctgaaa caaaatacaa cccaagctct ccgtactcat caaccaaggc
    18541 agcctcagat ttgattgtca aagcctgggt gcgttctttt ggagtcaagg caacgatttc
    18601 caactgttca aataactacg gtccttatca acatatcgaa aaattcatcc cacgtcagat
    18661 tactaacatc ctaagtggaa ttaagccaaa actttacggt gaaggtaaga atgttcgtga
    18721 ctggattcat accaatgacc attcttcagg agtttggaca atcttgacaa aagggcaaat
    18781 cggtgaaacc tacttgattg gggctgatgg tgagaagaac aataaggaag ttttggaact
    18841 tatccttaag gaaatgggac aagctacgga tgcctatgat catgtgactg accgtgcagg
    18901 acatgacctt cgctatgcga ttgatgccag caagctccgt gatgagttgg ggtggaaacc
    18961 tgaatttacc aactttgaag ctgggctcaa ggcaacaatc aagtggtata cagataacca
    19021 agaatggtgg aaagcagaaa aagaagctgt tgaagccaat tatgctaaga ctcaggagat
    19081 tattacagta taaaaagcag gaaatagctg ctttttattg ctatattggg aagagttaca
    19141 tattagaaag gtctagagat gattttaatt acaggggcaa atggccaatt aggaacggaa
    19201 cttcgctatt tattggatga acgtaatgaa gaatacgtgg cagtagatgt ggctgagatg
    19261 gacattacca atgaagaaat ggttgagaaa gtttttgaag aggtgaaacc gactttagtc
    19321 taccattgtg cagcctacac cgctgttgat gcagcagagg atgaaggaaa agagttggac
    19381 ttcgccatca atgtgacggg gacaaaaaat gtcgcaaaag catctgaaaa gcatggtgca
    19441 actctagttt atatttctac ggactatgtc tttgacggta agaaaccagt tggacaagag
    19501 tgggaagttg atgaccgacc agatccacag acagaatatg gacgcactaa gcgtatgggg
    19561 gaagagttag ttgagaagca tgtgtctaat ttctatatta tccgtactgc ctgggtattt
    19621 ggaaattatg gcaaaaactt cgtttttacc atgcaaaatc ttgcgaaaac tcataagact
    19681 ttaacagttg taaatgacca gtacggtcgt ccgacttgga ctcgtacctt ggctgagttc
    19741 atgacctacc tagctgaaaa tcgtaaggaa tttggttatt atcatttgtc aaatgatgcg
    19801 acagaagaca caacatggta tgattttgca gttgaaattt tgaaagatac agatgtcgaa
    19861 gtcaagccag tagattccag tcaatttcca gccaaagcta aacgtccgct aaactcaacg
    19921 atgagcctgg ccaaagccaa agctactgga tttgttattc caacttggca agatgcattg
    19981 caagaatttt acaaacaaga agtgagataa gtagtagaat gattttctag tctaataaaa
    20041 gaggcagata atgaactcca aaggagctta agatgtacga ttatcttgtt gttggtgctg
    20101 atctctttgg cgcatagctt tggctcagtt tctattatcg ctcacaccat ccatcagaag
    20161 tttaatctga aggtacccaa ttatcgccaa gaagaagatt gggctaggat gggtttacca
    20221 atcacacgta aggaaatctc taattggcat atcaaggcaa gtcaatacta tttagagtcc
    20281 ctttataacc ttttacgaga aaagttgtta gaacaacctc ttcttcatgc ggatgaaacc
    20341 tcttatcggg tgctagagag tgatagccat ctgacctact attggacctt tttgtctggg
    20401 aaagctgaga atcaagcaat cacgctgtac catcatgatc agcgtcggag tggtttagta
    20461 gtacaagaat tcctaggaga ttattctggc tatgtgcatt gtgatatgtt gcggcagtaa
    20521 cttaggactt tagtcctcta gttctgccta tgcgatagca gtccaaggtt taggagcaag
    20581 gcgacgctaa gcttggtaaa ctaagcttag cgtcaactgg aagaagctga acttgttgga
    20641 tgttgggcac atgtgagaag gaagtttttt gaagcgaccc ccaagcaagc agataaatca
    20701 tccttaggag ctaaaggttt agcttattgt gatcagttat tttccctgga aagagactgg
    20761 gaggctttgc cagctgatga acgactacag aaacgtcaag aacatctcca gcccttaatg
    20821 gaagacttct ttgcttagtg ccggcgtcag tcagttttag caggttcaaa actaggaagg
    20881 gcaattgaat acagcctcaa gtatgaagaa acctttaaga ctattttgaa agacggacat
    20941 ctggtccttt ccaataatct agctgaacgc gccattaaat cattggttat gggacggagt
    21001 aaaagaattc agtggactct tttagcctaa gctaaatttt aaaaagcgag ggtggttatt
    21061 ttctcaaagt tttgaaggag ctaaagcaac agctattatt atgagtttgt tggaaacagc
    21121 taaacgtcat caattaaata gcgagaaata tctattctat cttctagaat gtcttccaaa
    21181 cgaggaaact ctcgtaaaca aagaggtttt agaggcttat ttaccatgga ctaaagttgt
    21241 acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct
    21301 ggagattttt caatatactt cgttattgga cggttacgat attcatattt tttgcaaaga
    21361 tgttgtttga aaaataattt tcaaaaattc tgaaaattct gttgacaact ttctgaaaag
    21421 agtctataat ggagagaaag ttttaaagga gaaaatgatg aaaagttcaa aactatttgc
    21481 ccttgcgggc gtgacattat tggcggcgac tactttagct gcatgctctg gatcaggttc
    21541 aagcactaaa ggtgagaaga cattctcata catttatgag acagaccctg ataacctcaa
    21601 ctatttgaca actgctaagg ctgcgacagc aaatattacc agtaacgtgg ttgatggttt
    21661 gctagaaaat gatcgctacg ggaactttgt gccgtctatg gctgaggatt ggtctgtatc
    21721 caaggatgga ttgacttaca cttatactat ccgtaaggat gcaaaatggt atacttctga
    21781 aggtgaagaa tacgcggcag tcaaagctca agactttgta acaggattaa aatatgctgc
    21841 tgataaaaaa tcagatgctc tttaccttgt tcaagaatca atcaaagggt tggatgccta
    21901 tgtaaaaggg gaaatcaaag atttctcaca agtaggaatt aaggctctgg atgaacagac
    21961 agttcagtac actttgaaca aaccagaaag cttctggaat tctaagacaa ccatgggtgt
    22021 gcttgcgcca gttaatgaag agtttttgaa ttcaaaagga gatgattttg ccaaagctac
    22081 ggatccaagt agtctcttgt ataacggtcc ttatttgttg aaatccattg tgaccaaatc
    22141 ctctgttgaa tttgcgaaaa atccgaacta ctgggataag gacaatgtgc atgttgacaa
    22201 agttaaattg tcattctggg atggtcaaga taccagcaaa cctgcagaaa actttaaaga
    22261 tggtagcctt acagcagctc gtctctatcc aacaagtgca agtttcgcag aacttgagaa
    22321 gagtatgaag gacaatattg tctatactca acaagactct attacgtatc tagttggtac
    22381 aaatattgac cgtcagtcct ataaatacac atctaagacc agcgacgaac aaaaggcatc
    22441 gactaaaaag gctctcttaa acaaggattt ccgtcaggct attgcctttg gatttgaccg
    22501 tacagcctat gcctctcagt tgaatggaca aactggagca agtaaaatct tgcgtaatct
    22561 ctttgtccca ccaacatttg ttcaagcaga tggtaaaaac tttggcgata tggtcaaaga
    22621 gaaattggtc acttatgggg atgaatggaa ggatgttaat cttgcagatt ctcaggatgg
    22681 tctttacaat ccagaaaaag ccaaggctga atttgctaaa gctaaatcag ccttacaagc
    22741 agaaggagtc caattcccaa ttcatttgga tatgccagtt gaccaaacag caactacaaa
    22801 agttcagcgc gtccaatcta tgaaacaatc cttggaagca actttaggag ctgataatgt
    22861 cattattgat attcaacaac tacaaaaaga cgaagtaaac aatattacat attttgctga
    22921 aaatgctgct ggcgaagact gggatttatc agataatgtc ggttggggtc cagactttgc
    22981 cgatccatca acctaccttg atattatcaa accttctgta ggagaaagta ctaaaacata
    23041 tttagggttt gactcagggg aagataatgt agctgctaaa aaagtaggtc tatatgacta
    23101 cgaaaaattg gttactgagg ctggtgatga gactacagat gttgctaaac gctatgataa
    23161 atacgctgca gcccaagctt ggttgacaga tagtgctttg attattccaa ctacatctcg
    23221 tacagggcgt ccaatcttgt ctaagatggt accatttaca ataccatttg cattgtcagg
    23281 aaataaaggt acaagtgaac cagtcttgta taaatacttg gaacttcaag acaaggcagt
    23341 cactgtagat gaataccaaa aagctcagga aaaatggatg aaagaaaaag aagagtctaa
    23401 taaaaaggct caagaagatc tcgcaaaaca tgtgaaataa ctgttgcaaa atataagaaa
    23461 ggatttagta tttcccttga atgctgaatc cttttttaca tttgtaaaga aagattctaa
    23521 aatgtacgga cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta
    23581 attttacttg tttcctattg ctttctcagc tattatttgt tatattaaaa gtataattat
    23641 tttttattta tcagagttaa gcattgcact ttcagaggaa ggagtatttt ttaaaaagaa
    23701 aatgtaaacg cttgctcaaa aatgaaagga tttagaagtt tatgaataaa ggattatttg
    23761 aaaaacgttg taaatatagt attcggaaat tttcattagg tgttgcttct gttatgattg
    23821 gagctgcatt ctttgggaca agtccggttc ttgcagatag cgtgcagtct ggttccacgg
    23881 cgaacttacc agctgattta gctactgctc ttgcaacagc aaaagagaat gatgggcgtg
    23941 attttgaagc gcctaaggtg ggagaagacc aaggttctcc agaagttaca gatggaccta
    24001 agacagaaga agaactatta gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag
    24061 aggataaacc tgcagctgct aaacctgaaa cacctaagac ggtaacccct gaatggcaaa
    24121 cggtagcgaa taaagagcaa caaggaacag tcactatccg agaagaaaaa ggtgtccgct
    24181 acaaccaact atcctcaact gctcaaaatg ataacgcagg caaaccagcc ctgtttgaaa
    24241 agaagggctt gaccgttgat gccaatggaa atgcaactgt tgatttaacc ttcaaagatg
    24301 attctgaaaa gggcaaatca cgctttggtg tctttttgaa atttaaagat accaagaata
    24361 atgtttttgt cggttatgac aaggatggct ggttctggga gtataaatct ccaacaacta
    24421 gcacttggta tagaggtagt cgtgttgctg ctcctgaaac aggatcaaca aaccgtctct
    24481 ctatcactct caagtcagac ggtcagctaa atgccagcaa taatgatgtc aatctctttg
    24541 acacagtgac tctaccagct gcggtcaatg accatcttaa aaatgagaag aagattcttc
    24601 tcaaggcggg ctcttatgac gatgagcgaa cagttgttag cgttaaaacg gataaccaag
    24661 agggggtaaa aacagaggat acccctgctg aaaaagaaac aggtcctgaa gttgatgata
    24721 gcaaggtgac ttatgacacg attcagtcta aggtcctcaa agcagtgatt gaccaagcct
    24781 tccctcgtgt caaggaatac agcttgaacg ggcatacttt gccaggacag gtgcaacagt
    24841 tcaaccaagt ctttatcaat aaccaccgaa tcacccctga agtcacttat aagaaaatca
    24901 atgagacaac agcagagtac ttgatgaagc ttcgcgatga tgctcactta atcaatgcgg
    24961 aaatgacagt acgcttgcaa gttgtagaca atcaattgca ctttgatgtg actaagattg
    25021 tcaaccacaa tcaagtcact ccaggtcaaa agattgatga cgaaagcaaa ctactttctt
    25081 ctattagttt cctcggcaat gctttagtct ctgtttctag taatcaaact ggtgctaagt
    25141 ttgatggggc aaccatgtca aacaatacgc atgtcagcgg agatgatcat atcgatgtaa
    25201 ccaatccaat gaaggatttg gctaagggtt acatgtatgg atttgtttct acagataagc
    25261 ttgctgctgg tgtttggagt aactctcaaa atagctatgg tggtggttcg aatgactgga
    25321 ctcgtttgac agcttataaa gaaacagtcg gaaatgccaa ctatgtagga atccacagct
    25381 ctgaatggca atgggaaaaa gcttataagg gcattgtttt cccagaatac acgaaggaac
    25441 ttccaagtgc taaggttgtt atcactgaag atgccaatgc agacaagaaa gttgattggc
    25501 aagatggtgc cattgcttat cgtagcatta tgaacaatcc tcaaggttgg gaaaaagtta
    25561 aggatatcac agcttaccgt atcgcgatga actttggttc tcaagcacaa aacccattcc
    25621 ttatgacctt ggatggtatc aagaaaatca atctccatac agatggtctt gggcaaggtg
    25681 ttctccttaa aggatatggt agcgaaggcc atgactctgg tcacttgaac tatgctgata
    25741 ttggtaagcg tatcggtggt gtcgaagact tcaagaccct aattgagaag gctaagaaat
    25801 atggagctca tctaggtatc cacgttaacg cttcagaaac ttatcctgag tctaaatact
    25861 tcaatgaaaa aattctccgt aagaatccag atggaagcta tagctatggt tggaactggc
    25921 tagatcaagg tatcaacatt gatgctgcct atgacctagc tcatggtcgt ttggcacgtt
    25981 gggaagattt gaagaaaaaa cttggtgacg gtctcgactt tatctatgtg gacgtttggg
    26041 gtaatggtca atcaggtgat aacggtgcct gggctaccca cgttcttgct aaagaaatta
    26101 acaaacaagg ctggcgcttt gcgatcgagt ggggccatgg tggtgagtac gactctacct
    26161 tccatcactg ggcagctgac ttgacttacg gtggctacac caataaaggt atcaacagtg
    26221 ccatcacccg ctttatccgt aaccaccaaa aagatgcttg ggttggggac tacagaagtt
    26281 atggtggtgc agccaactat ccactgctag gtggctacag catgaaagac tttgaaggct
    26341 ggcaaggaag aagtgactac aatggctatg taaccaactt atttgcccat gatgtcatga
    26401 ccaagtactt ccaacacttc actgtaagta aatgggaaaa tggtacaccg gtgactatga
    26461 ccgataacgg tagcacctat aaatggactc cagaaatgcg agtggaattg gtagatgctg
    26521 acaataataa agtagttgta actcgtaagt caaatgatgt caatagtcca caatatcgcg
    26581 aacgtacagt aactctcaac ggacgtgtca tccaagatgg ttcagcttac ttgactcctt
    26641 ggaactggga tgcaaatggt aagaaacttt ctactgataa ggaaaagatg tactacttca
    26701 atacgcaggc cggtgcaaca acttggaccc ttccaagcga ttgggcaaag agcaaggttt
    26761 acctttacaa gctaactgac caaggtaaga cagaagagca agaactaact gtaaaagatg
    26821 gtaaaattac cctagatctt ctagcaaatc aaccatacgt tctctatcgt tcgaaacaaa
    26881 ccaatcctga aatgtcatgg agtgaaggca tgcacatcta tgaccaagga tttaacagtg
    26941 gtaccttgaa acattggacc atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc
    27001 aaggggcaaa cgatatgctt cgtattcaag gaaacaaaga aaaagttagt ctcactcaga
    27061 aattaactgg cttgaaacca aataccaagt atgccgttta tgtcggtgtc gataaccgta
    27121 gtaatgccaa ggcgagcatc actgtaaata ctggtgaaaa agaagtgact acttatacca
    27181 ataagtctct cgctctcaac tatgttaagg cctacgccca caatacacgt cgtgacaatg
    27241 ctacagttga cgatacaagt tacttccaaa acatgtacgc cttctttaca actggatcgg
    27301 acgtctcaaa tgttactctg acattgagtc gtgaagctgg tgatcaagca acttactttg
    27361 atgaaattcg tacctttgaa aacaattcaa gcatgtacgg agacaagcat gatacaggtc
    27421 aaggaacctt caagcaagac tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg
    27481 gtggtgtcga aggtgtcgaa gacaaccgca ctcacttgtc tgaaaaacac gatccatata
    27541 cacaacgtgg ttggaacggt aagaaagttg atgatgttat cgaaggaaat tggtcactca
    27601 agacaaatgg actagtgagc cgtcgtaact tggtttacca aactattccg caaaacttcc
    27661 gttttgaagc aggtaagacc taccgtgtaa cctttgaata cgaagcaggt tcagacaata
    27721 cctatgcttt tgtagtcggt aagggagaat tccagtcagg tcgtcgtggt actcaagcaa
    27781 gcaacttgga aatgcatgaa ttgccaaata cttggacaga ttctaagaaa gccaagaagg
    27841 caaccttcct cgtgacaggt gcagaaacag gggatacttg ggtaggtatc tactcaactg
    27901 gaaatgcaag taatactcgt ggtgattctg gtggaaatgc caacttccgt ggttataacg
    27961 acttcatgat ggataatctt caaatcgaag aaattaccct aacaggtaag atgttgacag
    28021 aaaatgctct gaagaactac ttgccaacgg ttgccatgac taactacacc aaagagtcta
    28081 tggatgcttt gaaagaggcg gtctttaacc tcagtcaggc cgatgatgat atcagtgtgg
    28141 aagaagcgcg tgcagagatt gccaagattg aagccttgaa gaatgctttg gttcagaaga
    28201 aaacggcttt ggtagcagat gactttgaaa gtttggatgc gccagctcaa ccaggtgaag
    28261 gtcttgagaa tgcctttgat ggcaatgtgt ctagtctatg gcatacatca tggggcggag
    28321 gagatgtagg caagcctgca accatggtct tgaaagaagc aactgaaatc actggacttc
    28381 gttatgttcc acgtggatca ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga
    28441 cagctgagtc tggcaaggag cataccttta ctgcaactga ttggccagat aacaataagc
    28501 caaaagacat tgattttggt aagacaatta aggctaagaa aattgtcctt acaggtacta
    28561 agacttacgg agatggtggc gataaatacc aatctgcagc ggaacttatc tttactcgtc
    28621 cacaggtagc agaaacacct cttgacttgt caggctatga agcagctttg gctaaggctc
    28681 agaaattaac agacaaagac aatcaagagg aagtagctag cgttcaggca agcatgaaat
    28741 atgcgacgga taaccatctc ttgacggaaa gaatggtgga atactttgca gattatctca
    28801 accaattaaa agattctgct acgaaatcag atgctccaac tgtagagaaa cctgagttta
    28861 aacttagctc tttagcttcc gaacaaggta agacgccaga ttataagcaa gaaatagata
    28921 gaccagaaac acctgaacaa atcttgccag caacaggtga gagtcaatct gacacagccc
    28981 tcttcctagc aggtgttagc ctagccctat ctgctctctt tgtagtaaaa acgaagaaag
    29041 actagtattt agtaaaacct cttaaccaga ttacggaagc agtctctatc ttttccaatg
    29101 aggtttatag tacagaaaaa gcctgagaag atgtcttctc aggcttttgt taagcacata
    29161 aatacaatag tgctatgaaa aaatcaccca gaaaaatctg tatgataaat gttatggttg
    29221 tgctggttga ggattctgat tttgttgatc aggggttgta tttgattgtt gcgtattatt
    29281 gttaggattg gtagtcgtac tattatttgt gcttggagtg gttgagctag actgtgaagt
    29341 tgaactatct gatgatgagc ttgaactttc agttgatggg ggttgttgtg gagcaggtga
    29401 gctccacgta gaacgagcac catttttaaa tacgaattct ccatttctgt agagcccctc
    29461 tggtatattc caatcctctg gattgcttcc ttcagacaga taggtcatca tagagcggta
    29521 aactttggca gcgaccgtaa ggccattgcc tacaagtggt gtcagacggt tagaatagcc
    29581 tgtccataca gccattgaat atttacgcgt atagccagca aatagttcat caggtgctac
    29641 aaattgagag gtcttgatgt ggttttcaat ttcctcgtct gtatagttag aggttcctgt
    29701 tttaccagcc tgagggagcc aagcaagata ggcatttcgt ccagttccat aagtcaagac
    29761 tgttttcatc atgtcggtca tcatataggc tgttgtttcc ttcatggcac gagttccgac
    29821 attagagaac tctttttcac tcccatcact aaagacgact ttatggatat acattggttt
    29881 atagtaagtt ccaccatttg caaaagcagc gtaagcagca gccatctttt cactacttgc
    29941 tccatatttt ttgtctgatt cggttgtgtt acttgaaatg gcatttgagt agtgaatact
    30001 tgggtagtcg attccgagac catttaggaa agtcttggcg cggttgagtc cgaccttgtt
    30061 tagagtttcc acggctggga cgtttcgcga ttgttgcagg gcgtattgca aggtgatgtt
    30121 gccaaagtag cccctatccc agttataaac aggagtattt gtcccagggt agttataggg
    30181 ctcatcgtga acgatagtag cagttgaatc gtagacaccg tactccaagg caggagcata
    30241 gtctgtgatc ggtttcatag ttgatcccca gtcgcggttt gtttctactg cttggttaat
    30301 tccgaaagaa acattacttg actgatggcg tgctcctagc tgggcaatga ctttaccgtt
    30361 agaaacatca acaatggtag aagcgacttg caattcatcg tctggatagg caacgtattc
    30421 gtctgtattg taaatatccc acagatgttt ttgagcttct tggtctacat ttgtgtagac
    30481 atccatccca gttgtgagta ggttatagcc tgtttcttct tcaacttgat tgatgacttc
    30541 cttgaggtaa ttatccatgt aagcagggta attacttgct gatttgagac tttgtagccc
    30601 atcagtaatt ggtgtattga ctgctttctc atactgttca gcagagatgt agccttgatt
    30661 tttcatttca gataagacca agtttcggcg gtcttgggct gcttctggat gtgaataggg
    30721 gtcatattgg tttggtgcct gaggcattcc agccagcaag gctaactgag gtaaacttaa
    30781 attattgagg tctttaccat agtagttttg agctgctgtc tgcattccat agttcccatt
    30841 agacatgtag accttattta tatagtaggt caagatttct tgcttggttg ctttttgttc
    30901 taactgaatc gctaaccaag cttcctgagc cttacgagaa atagtctggt cggaagtcga
    30961 agttgaaaag taagtcaact taatcaactg ttgagtgaga gttgatccac cttggaggga
    31021 attgctttgc agattgcgca agaaagctcc caggatacgg atggtatcaa tccccctgtg
    31081 gtcgaagaag cgatggtctt cgatagaaac gattgcctta accaaatctg tgggaatatc
    31141 attagcttgg gcattgacgc ggcgttcaga acccaagtca gcaatgagtt gatttttatt
    31201 gtcgtagatt ttactagaag ttgttgcaac tagtttactc tcggataggc taggagcctt
    31261 gctaacgtag tagaaaaaaa ctcctccgcc taagacaatg gctgcgataa ccaagcttaa
    31321 gaagctaatg ctcagatact tgattaggcg cagaatcgtt ggtttgttca tcttgtttta
    31381 ccacctaata aatgttcttt gataacattg agataaggaa tttgagggaa ggcaccagcc
    31441 ttgatttcat atccatattc tcgaatatat tcaagtggca ttgatttttg tcccttatct
    31501 tgatgataga agcgaatcaa atcgaatgcc ggcaataagt aggtttcttg ctgagaagaa
    31561 aagtgaagaa ggacaaagca gattccttgt tgggcaagga cttgttccat atgctgaatc
    31621 tgatgtggat gaaaattttt catcggaatc gcacgttttt gttttgtttc cttgacttca
    31681 aagtcgatgt aatatccatt ataaacgcca gaatagtccg tcgttgaagc ttgtcgaaaa
    31741 taggcttcaa caatcttggc acgacttcgt tgtggatagt ccacttgtac gatttgaata
    31801 ggagttggtt tcttatgtat aacagccaag ccctgagaca aatagtagtc gttggtagca
    31861 ttgatcatct tttcaaaaga cattcctcga tttgcgaaat ttttgggttg agaaagagat
    31921 gtttgtcttt tttgtgatga aactttatgt ggatagttga ccataattct ccttattggt
    31981 acaataacat cactttatta taccataatt tgcacagaaa gggttaaaaa tggctacagc
    32041 tttggtttta ggctattctg cttttgattt gggtttattt tctgataagg atcctcgtct
    32101 taaattgatt aaaaaagcga tacgtaaaga tttagaggct atggcagcag atggggtgtc
    32161 ttggcttgtg tttacaggga gtttggggtt tgaatattgg gttttagagg ttgctcagga
    32221 gatgaaaacc gaatacggtt tccagttggc caccattttt gcttttgaaa cccatgggga
    32281 aaattggaat gaaggcaatc agatgaaact gagtcgcttt aagcaggtag actttgtcaa
    32341 atatgcttat cctcgctatg aacacaaggg gcagttaaga gattaccagc agtttttgct
    32401 ggaaaacacg actagttcct atctttttta tgatgaagaa aatgaaacga aactagctta
    32461 tttttaccaa aagatgaaaa atcaagagga ctattttata aagagattaa catttgatca
    32521 attaaatgaa cttgctgaaa atttttccga aaattgaagc tttgaccttg atttttgttt
    32581 gccttttttt atataataat actagcaagc gagaatggag agagacatgg caagtattat
    32641 tttttcagcg aaagatattt ttgaacaaga gtttggacgt gaagtccgtg gctataataa
    32701 agtagaagtt gacgagtttt tagacgatgt catcaaggac tatgaaacct atgctgcctt
    32761 ggtcaagtca cttcgtcagg aaattgcgga tttgaaggaa gaattaactc gtaaaccgaa
    32821 accttcacca gttcaagcag aaccccttga agcggcaatt acaagttcta tgacgaattt
    32881 tgatattttg aaacgcctga atagattgga aaaagaagtt tttggtaaac aaattttaga
    32941 taactcagat ttttaagtag ttatttgaga tgtgcaattt ttggataatc gcgtgaggag
    33001 aattgcttct catgaggaaa gtccatgcta gcacaggctg tgatgcctgt agtgtttgtg
    33061 ctaggcgaaa ccataagcct agggacgaga aatcgttacg gcagttgaaa tggctaagtc
    33121 cttggatagg ccagagtaga cttgaaagtg ccacagtgac ggagtctttc tggaaacaga
    33181 gagagtggaa cgcggtaaac ccctcaagct agcaacccaa attttggtcg gggcatggag
    33241 tacgcggaaa cgaacgtagt attctgactg ctatcagcta gagctgttag tggtagacag
    33301 atgattatcg aaggaagtgg tcctagtcac ttctggaaca aaacatggct tatagaaaat
    33361 tgcatatagg ttggggctga gaaattttct caacctcatt ttttaaagtg gacatataga
    33421 aaggtcttgc aagactgtaa catgaaaaaa gaatttaatt taattgcaac tgtggcagca
    33481 gggcttgagg ctgtcgttgg tcgtgaagtg cgagagttgg gctacgattg tcaggttgaa
    33541 aatggacgtg ttcgttttca aggagacgtg agagctatta tcgaaaccaa cctttggctt
    33601 cgggcagcag atcgtatcaa aattatcgta ggaacgttcc cagctaagac ttttgaagag
    33661 ctatttcagg gagttttcgc tttagattgg gaaaattatt taccacttgg agctcggttc
    33721 ccgatttcaa aagctaaatg tgttaagtcc aaacttcaca atgagcctag tgttcaggct
    33781 atttctaaga aagctgttgt caagaaattg cagaaacact atgctcgccc agaaggggtt
    33841 cctctgatgg agaatggccc agagtttaag attgaggtct ctattctcaa agatgtggca
    33901 actgtcatga ttgatacgac cgggtctagc ctctttaaac gtggttatcg taccgaaaaa
    33961 ggtggcgctc ctatcaagga aaatatggca gcagccattt tacaactttc taactggtac
    34021 ccagacaagc ctttgattga tccgacctgt ggttcgggga ctttctgtat tgaggcagtt
    34081 atgattgcta gaaagatggc gccaggtctt cgtcgctctt ttgcatttga ggaatggaac
    34141 tggatcagcg atcgcttgat tcaagaagtg cgcacagaag cggctaaaaa agtagaacgt
    34201 gagcttgagc tggatatcat gggctgtgat attgatgctc gcatggtgga aattgctaag
    34261 gccaatgctc aggcagctgg tgttgcagga gacattactt ttaagcagat gcgcgtgcag
    34321 gatttacgtt ccgataaaat caatggagta atcatttcca atccgcctta tggtgaacgt
    34381 ttgtcagatg atgcaggggt gaccaagctc tatgctgaga tggggcaagt atttgcaccg
    34441 ctgaaaactt ggagcaaatt tatcctgact agtgatgaag cttttgaaag caagtatggt
    34501 agccaagcag ataagaagcg taagttatac aacggaacct tgaaagtgga tttatatcaa
    34561 tattttggtc agcgtgtcaa acggcaagag gtaaaataga aagggatact catgagtaaa
    34621 aaaagacgaa atcgtcataa aaaagaagct caagaaccgc aatttgattt tgatgaagca
    34681 aaagagctaa cagttggtca agctattcgt aaaaatgaag aagtggaagc aggagtcttg
    34741 cctgaggatt ccattttgga caagtatgtt aagcaacaca gagatgaaat tgaggcggat
    34801 aagtttgcga ctcgtcaata caaaaaagag gagttcgttg aaactcagag tctggatgat
    34861 ttaattcaag agatgcgtga ggctgtagag aagtcagaag cttcttcgga ggaagttcca
    34921 tcttctgaag acatcttact acccttgcct ctggacgatg aggagcaagg cttggatcct
    34981 ctattgctag atgatgaaaa tccaacagaa atgactgaag aagtggaaga ggagcaaaac
    35041 ctttctcgtc tggatcaaga ggactcagaa aagaaaagta aaaaaggctt tattttgacc
    35101 gttttggcgc ttgtatcagt aattatttgt gtcagtgctt attatgtcta tcgtcaagtg
    35161 gctcgttcga ccaaggaaat tgaaacttct caatcaacta cagccaatca atcggatgtg
    35221 gatgatttta atacacttta tgacgccttt tacacaaata gcaataaaac ggctttgaaa
    35281 aatagccagt ttgataaact gagtcaactc aagactttac ttgataagct ggaaggtagt
    35341 cgtgaacata cgcttgccaa atctaaatat gatagtctag taacgcaaat caaggccatt
    35401 caagatgtca atgcacaatt tgaaaaacca gctattgtgg atggtgtgtt ggataccaat
    35461 gccaaagcca aatcggatgc taaatttacg gatattaaaa ctggaaatac ggagcttgat
    35521 aaagtgctag ataaggctat cagtcttggt aagagccagc aaacaagtac ttctagctca
    35581 agttcaagtc aaactagcag ctcaagttca agtcaagcaa gttcaaatac gactagtgag
    35641 ccaaaaccaa gtagttcaaa tgagactaga agtagtcgca gtgaagtcaa tatgggtctc
    35701 tcgagtgcag gggttgctgt tcaaagaagt gccagtcgtg ttgcctataa tcagtctgct
    35761 attgatgata gtaataactc tgcctgggat tttgcggatg gtgttttgga acaaattcta
    35821 gcaacttcac gttcacgtgg ctatatcact ggagaccaat atatccttga acgtgtcaat
    35881 atcgttaacg gcaatggtta ttacaacctc tataagccag atggaaccta tctctttacc
    35941 cttaactgta agacaggcta ctttgtcgga aatggcgctg gtcatgcgga tgacttggac
    36001 tactaagcag tcgttacaaa attctttctt ttcaaaagta aaaatgataa aataaaacaa
    36061 atgaaacaag aggagtgtca aatgacaaaa gctaactttg gtgtcgtagg tatggccgta
    36121 atgggtcgta accttgccct taatattgaa tcacgtggtt acacagttgc tatctacaac
    36181 cgtagtaaag aaaaaacgga agatgtgatt gcttgccatc ctgaaaagaa ttttgtacca
    36241 agctatgacg ttgaaagttt tgtaaactca atcgaaaaac ctcgtcgtat catgctgatg
    36301 gttcaagctg gacctggtac agatgctact atccaagccc ttcttccaca ccttgacaaa
    36361 ggtgatatct tgattgacgg aggaaacact ttctacaaag ataccatccg tcgtaatgaa
    36421 gaattggcaa actcaggtat caactttatc ggtactggag tttctggtgg tgaaaaaggt
    36481 gcccttgaag gtccttctat catgcctggt ggacaaaaag aggcctacga attggtttcg
    36541 gatgttcttg aagaaatctc agctaaagca ccagaagatg gcaaaccatg tgtgacttat
    36601 atcggtcctg atggagctgg tcactatgtg aaaatggttc acaacggtat cgagtacggt
    36661 gatatgcaat tgatcgcaga aagctatgac ttgatgcaac acttgctagg cctttctgca
    36721 gaggatatgg ctgaaatctt tactgagtgg aacaagggtg aattggatag ctacttgatc
    36781 gaaatcacag ctgatatctt gagccgtaaa gacgatgaag accaagatgg accaatcgta
    36841 gactacatcc ttgatgctgc aggtaacaag ggaactggta aatggacgag ccaatcatct
    36901 cttgaccttg gtgtaccatt gtcactgatt actgagtcag tgtttgcacg ctacatttca
    36961 acttacaaag aagaacgtgt acatgctagc aaggtgcttc caaaaccagc tgccttcaac
    37021 tttgaaggag acaaggctga attgattgaa aaaatccgtc aagcccttta cttctcaaaa
    37081 atcatttcat acgcacaagg atttgctcaa ttgcgtgtag cctctaaaga aaacaactgg
    37141 aacttgccat ttgcagatat cgcatctatc tggcgtgatg gctgtatcat ccgttctcgt
    37201 ttcttgcaaa agattacaga tgcttacaac cgcgatgcag atcttgccaa ccttcttttg
    37261 gacgagtact tcttggatgt tactgctaag taccaacaag cagtacgtga tatcgtagct
    37321 cttgcggttc aagcaggtgt gccagtgcca actttctcag cagctattac ttactttgat
    37381 agctaccgtt cagctgacct tccagctaac ttgatccaag cacaacgtga ctactttggt
    37441 gctcacactt accaacgtaa agacaaagaa ggaaccttcc actactcttg gtatgacgaa
    37501 aaataagtag gtcagccatg gggaaacgga ttttattact tgagaaagaa cgaaatctag
    37561 ctcatttttt aagtttggaa ctccagaaag agcagtatcg ggttgatctg gtagaggagg
    37621 ggcaaaaagc cctttccatg gctcttcaga cagactatga tttgatttta ttgaatgtta
    37681 atctgggaga tatgatggct caggattttg cagaaaaatt gagtcgaact aaacctgcct
    37741 cagtcatcat gattttagat cattgggaag acttgcaaga agagctgaaa gttgttcagc
    37801 gttttgcagt ttcatacatc tataagccag tctttatcga aaatctggta gcgcgtattt
    37861 cggcgatctt ccgaggtcgg gacttcattg atcaacactg cagtctgatg aaagttccaa
    37921 ggacctaccg caatcttagg atagatgttg aacatcacac ggtttatcgt ggtgaagaga
    37981 tgattgctct gacccgccgt gagtatgacc ttttggcgac acttatggga agtaagaaag
    38041 tattgactcg tgagcaattg ttggaaagtg tttggaagta tgaaagtgcg accgagacaa
    38101 atatcgtaga tgtctatatc cgctatctac ggagcaagct tgatgttaaa ggccaaaaaa
    38161 gctacattaa aaccgtgcgt ggtgttggtt acaccatgca agaatagaaa agcagttgca
    38221 gttgtgtaac tgcttttttg aggagttttt atatattgac atacaatcta gtttttacta
    38281 caatcgtttt aggaggatat ataaaatgaa gcttttgaaa aaaatgatgc caatcgcatt
    38341 agcagtcttt ttctttggtt tgctagcgac aagtacagta tttgcagata ctatgggtgg
    38401 ccgatttgtt gataaggata atagaaaata ttatgtaaaa gatgatcata aagcaatcta
    38461 ttggcataaa atagacggta aaacttacta ttttggtgat attggagaga tggttgtcgg
    38521 ttggcaatac ttagaaattc atggaacagg ttatcgtgat gatttatttg ataatcgtcc
    38581 agtcttcgaa attggccttc aggagaagtg gtactatttt ggacaagatg gtgctttgct
    38641 agaacaaaca gataaacaag tactagaggc aaaaacgtct gaaaatacag gaaaagtata
    38701 cggtgaacaa tatcctctat ctgctgaaaa gaaaacttat tattttgata ataattatgc
    38761 tgtaaagaca ggctggattt atgaagacgg caattggtat tatttaaata agctaggaaa
    38821 ttttggcgat gattcttaca atccactacc aattggtgaa gttgctaagg gttggactca
    38881 agattttcat gttactattg acattgatag aagcaaacct gctccatggt actacctaga
    38941 tccagcaact ggcatcatgc aaactggttg gcaatttcta ggtaatagat ggtactacct
    39001 ccgttcatca ggagcaatgg caactggttg gtatcaagat ggttcaactt ggtactattt
    39061 agatccttct aatggagata tgaaaatagg ttggacaaaa gtaaatggaa actggtatta
    39121 tctcaattcc tctggagcaa tggttacagg tagccaaact atcgatggta aagtttataa
    39181 tttcgcctca tctggtgagt ggatttaata ttggagggta tatagatgaa aattttgaaa
    39241 aaaactatgc aagttggact gacagtattt ttctttggtt tgctagggac cagtacagta
    39301 tttgcagatg attctgaagg atggcagttt gtccaagaaa acggaagaac ctactacaaa
    39361 aagggggacc tcaaagaaac ctactggcga gtgattgatg gtaagtacta ttattttgat
    39421 tctctatctg gagagatggt tgtcggctgg caatatatcc cgtttccatc taaaggtagt
    39481 acaattggtc cttacccaaa tggtatcaga ttagaaggtt ttccaaagtc agagtggtac
    39541 tacttcgata aaaatggagt gctacaagag tttgttggtt ggaaaacatt agagattaaa
    39601 actaaagaca gtgttggaag aaagtacggg gaaaaacgtg aagattcaga agataaagaa
    39661 gagaagcgtt attatacgaa ctattacttt aatcaaaatc attctttaga gacaggttgg
    39721 ctttatgatc agtctaactg gtattatcta gctaagacgg aaattaatgg agaaaactac
    39781 cttggtggtg aaagacgtgc ggggtggata aacgatgatt cgacttggta ctatttagat
    39841 ccaacaactg gtattatgca aacaggttgg caatatctag gtaataactg gtactacctc
    39901 cgttcctcag gagcaatggc cactggctgg tatcaggaag gtaccacttg gtattattta
    39961 gaccagccaa atggcgatat gaaaacaggt tggcaaaacc ttgggaacaa atggtactat
    40021 ctccgttcct caggagctat ggcaactggt tggtatcaag atggttcaac ttggtactac
    40081 ctaaatgcag gtaatggaga tatgaagaca ggttggttcc aggtcaatgg caaatggtat
    40141 tatgcctatg gttcaggtgc tttggcagtg aatacgaccg tagacggcta ttctgtcaat
    40201 tataatggcg actgggttcg gtaatgacag ggtgcttata attatattag aacactcgct
    40261 taatcaaaga agtgactttg ttgtacttga cctgacgatt ggggagatta aaaagcatgt
    40321 gaaatctaca catgcttttt tgttagttat gagtgttgaa cttgactaac cattgacaaa
    40381 agataagagc aatcaaaata agatacaaaa atatcaatgc taactgcacc gaaacgcccg
    40441 atgctatgga tagggctaat agggagagca gggacggggc gagaatgtcc actgtgctca
    40501 gagcagagcc caccgtcccc atcttgtcac tggggatata ggcaaagaca gctgcttgta
    40561 ggcgagggct gagaatgcct ataatcgtag aactgatgaa actggtcatg aaaattacga
    40621 tataggcttg ataaaggata ctagttatta gagccaatag ggaaatctca cagaaaacca
    40681 agaggtgcgt gaaacggata tttttaaata gattactgct ggtcatattg ccaaggatag
    40741 ctccacaaga catgatgatg gagagcaggg cgaggagttg cccaatgctt agttgtgcta
    40801 gtgtttgttg gatgaagcgg agggcaatca gccgagggga cacatccaag atggcaatca
    40861 tactggtcgt cagaaacagt agtatgacgg tatcttttaa cctcaggagc acagccagcg
    40921 attgtttaag atgttgaaaa tatttcttaa aactcagtgc tgtatgtgac atttcaattc
    40981 ttttttcaac ctcatacaag gtatgtcgaa taacatacag gcccaaaaag gcaatgacaa
    41041 aagtcagagt gttgataagg gaaatagttt gaatacttat aacattgata aggaatgcgc
    41101 cagccagatt ggcgacaatg cggacaaccc tcatcagaga ctgcctgaac cccatggcat
    41161 catgcaggtc gtccttaatt acactgatgt agagggcgtt catcatgtag gcagacaggt
    41221 agctcaaggt gtcagagatg aggttgatga tgacaatcat aatgactgaa actaatgaaa
    41281 agggcgacaa gacgagaaat actgtcaaaa tagcgtagag caggattttg attttggcaa
    41341 tccagagtgc gtgtttgact ctattttctt gaaaatctcc tagaattccg agaaagagtt
    41401 gcgatagtag gggaaccacc tctgaaatgg aaatcagtaa aatcgctagc ggagcgaaat
    41461 tgtactgagc cacataattg ataatggcga ggtagaaaat actgtcgccg aatgatgaaa
    41521 aacagctgtt tagcagcaac tgtctatata tgttgtttgt ccaaaataat ttcatacatt
    41581 tctccttatg tttgcacatc gaatgggaat ttattattta gtagacacca atataccccc
    41641 tgcttcctat tccgaagtca aacaaatctg ctttaccact atctccttga aacatcagta
    41701 aaccgtgatc atctcgttca gaacatgcta aaattacctg ttggattttt ttcatcagta
    41761 atttgttttg attgtagaca gtggtttgta gtaagctagt tattccgtgg caatatcctg
    41821 tcatcatttt tagatgatgg ttaaaaacaa attcttgata tttactaata atatctttgt
    41881 ttccgtcaca atcgtacata caaagatata agattattcc ggaaattcct tcgcaccaag
    41941 aaagttgtaa atttcctaaa ttttcagtat tagaagtaac tttttctaat aattttttta
    42001 attcagtatg gaatgtatgg agatcattat agaacataga aggttctaag actttagaat
    42061 aggcaaataa agcatatgca attccacaat atccatgagc aaagctatag tctaaaatgc
    42121 tttctttggc tgtatctctt tgtaggaaat aatgataaat ttccccatat actattgtgg
    42181 atgaaagttt taagagtatt gtcattggta aattgatagt attttattaa tgataatagg
    42241 acatcagatt ttcccaatgc aaagtctatt tcctctagag tatcataatt ctctattaat
    42301 ttcttagagg tgacgtttgc taattgtaga tagtattgat ttttactgat agaaaataaa
    42361 tgtaggagta actatagata gcctgcatca ccaaatagca gtgagtattg atattcatat
    42421 gtgtgtgtcg ttctaattgt cactgccttc ttgatgatag agagtatttt agaatccagt
    42481 tctggggggt acaatttatt tagaggaaac agtagtccag ctattcagtg ttggaatgat
    42541 aaattactta cgaaatttcc aaattctgtt gaagaagtga tccttccttc agaatttaca
    42601 gttttatcta gtaaaaatcg tagaacactg ttacattctg ttttgtaatc atatttatgt
    42661 tcctctattt ttttaatttt gactaaatta tttgtttgac ttaaatttag tagatattgt
    42721 aaccaaaata gttgctcatt tgtgagctga ccttgagtat gtgatagttc tagtaattga
    42781 ataggatcct ttaggtagat tcaatcaatc tataacacaa caacataata acacttttag
    42841 gataacttgt cgatattata gtaaaatgaa ataataacag gacaaatcga tcaggacagt
    42901 caaa
//
LOCUS       DBEJJE010000015        39648 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEJJE010000015 DBEJJE010000000
VERSION     DBEJJE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.15"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            199..537
                     /locus_tag="ACL3F5_000790"
     CDS             199..537
                     /locus_tag="ACL3F5_000790"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGR0514627.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            727..2163
                     /locus_tag="ACL3F5_000791"
     CDS             727..2163
                     /locus_tag="ACL3F5_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0514628.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2215..2454
                     /locus_tag="ACL3F5_000792"
     CDS             2215..2454
                     /locus_tag="ACL3F5_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGR0514629.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2584..2895
                     /locus_tag="ACL3F5_000793"
     CDS             2584..2895
                     /locus_tag="ACL3F5_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGR0514630.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILEN
                     I"
     gene            3013..4992
                     /locus_tag="ACL3F5_000794"
     CDS             3013..4992
                     /locus_tag="ACL3F5_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0514631.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLLKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQSFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5002..5316
                     /locus_tag="ACL3F5_000795"
     CDS             5002..5316
                     /locus_tag="ACL3F5_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGR0514632.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5347..5853
                     /locus_tag="ACL3F5_000796"
     CDS             5347..5853
                     /locus_tag="ACL3F5_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514633.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5933..7279
                     /gene="celB"
                     /locus_tag="ACL3F5_000797"
     CDS             5933..7279
                     /gene="celB"
                     /locus_tag="ACL3F5_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGR0514634.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFTSKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7659..7835
                     /locus_tag="ACL3F5_000798"
     CDS             7659..7835
                     /locus_tag="ACL3F5_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514635.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8236..10449
                     /locus_tag="ACL3F5_000799"
     CDS             8236..10449
                     /locus_tag="ACL3F5_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR0514636.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFATEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTIQN"
     gene            complement(10671..11147)
                     /locus_tag="ACL3F5_000800"
     CDS             complement(10671..11147)
                     /locus_tag="ACL3F5_000800"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0514637.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLISRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11370..14573
                     /locus_tag="ACL3F5_000801"
     CDS             11370..14573
                     /locus_tag="ACL3F5_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0514638.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIDNNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14926..15302
                     /gene="tnpA"
                     /locus_tag="ACL3F5_000802"
                     /pseudo
     CDS             14926..15302
                     /gene="tnpA"
                     /locus_tag="ACL3F5_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            15484..15546
                     /locus_tag="ACL3F5_000803"
                     /pseudo
     CDS             15484..15546
                     /locus_tag="ACL3F5_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15690..16319)
                     /locus_tag="ACL3F5_000804"
     CDS             complement(15690..16319)
                     /locus_tag="ACL3F5_000804"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGR0514639.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16329..17330)
                     /locus_tag="ACL3F5_000805"
     CDS             complement(16329..17330)
                     /locus_tag="ACL3F5_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0514640.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17361..18002)
                     /locus_tag="ACL3F5_000806"
     CDS             complement(17361..18002)
                     /locus_tag="ACL3F5_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0514641.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18021..18836)
                     /locus_tag="ACL3F5_000807"
     CDS             complement(18021..18836)
                     /locus_tag="ACL3F5_000807"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0514642.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNTEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19106..19540
                     /locus_tag="ACL3F5_000808"
     CDS             19106..19540
                     /locus_tag="ACL3F5_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0514643.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19552..20742
                     /locus_tag="ACL3F5_000809"
     CDS             19552..20742
                     /locus_tag="ACL3F5_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0514644.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20753..21244
                     /locus_tag="ACL3F5_000810"
     CDS             20753..21244
                     /locus_tag="ACL3F5_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0514645.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELNQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21259..22038
                     /locus_tag="ACL3F5_000811"
     CDS             21259..22038
                     /locus_tag="ACL3F5_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0514646.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22025..22843
                     /locus_tag="ACL3F5_000812"
     CDS             22025..22843
                     /locus_tag="ACL3F5_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0514647.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            22843..23136
                     /gene="yajC"
                     /locus_tag="ACL3F5_000813"
     CDS             22843..23136
                     /gene="yajC"
                     /locus_tag="ACL3F5_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0514648.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23158..25059
                     /locus_tag="ACL3F5_000814"
     CDS             23158..25059
                     /locus_tag="ACL3F5_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0514649.1"
                     /translation="MKEERRQFFERIDGNQCRDYILPHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25119..26120
                     /locus_tag="ACL3F5_000815"
     CDS             25119..26120
                     /locus_tag="ACL3F5_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0514650.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26230..26565)
                     /locus_tag="ACL3F5_000816"
     CDS             complement(26230..26565)
                     /locus_tag="ACL3F5_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514651.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPIQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26576..26818)
                     /locus_tag="ACL3F5_000817"
     CDS             complement(26576..26818)
                     /locus_tag="ACL3F5_000817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514652.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26834..27028)
                     /locus_tag="ACL3F5_000818"
     CDS             complement(26834..27028)
                     /locus_tag="ACL3F5_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0514653.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27194..28144
                     /gene="rsmH"
                     /locus_tag="ACL3F5_000819"
     CDS             27194..28144
                     /gene="rsmH"
                     /locus_tag="ACL3F5_000819"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0514654.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28156..28473
                     /gene="ftsL"
                     /locus_tag="ACL3F5_000820"
     CDS             28156..28473
                     /gene="ftsL"
                     /locus_tag="ACL3F5_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0514655.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            28477..30729
                     /gene="pbp2X"
                     /locus_tag="ACL3F5_000821"
                     /gene_synonym="pbpX"
     CDS             28477..30729
                     /gene="pbp2X"
                     /locus_tag="ACL3F5_000821"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0514656.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            30731..31711
                     /gene="mraY"
                     /locus_tag="ACL3F5_000822"
     CDS             30731..31711
                     /gene="mraY"
                     /locus_tag="ACL3F5_000822"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0514657.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVYLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32320..34425
                     /locus_tag="ACL3F5_000823"
     CDS             32320..34425
                     /locus_tag="ACL3F5_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0514658.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMKDGVLVIREKA"
     gene            complement(34720..35202)
                     /locus_tag="ACL3F5_000824"
     CDS             complement(34720..35202)
                     /locus_tag="ACL3F5_000824"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0514659.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRIRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(35297..36781)
                     /locus_tag="ACL3F5_000825"
     CDS             complement(35297..36781)
                     /locus_tag="ACL3F5_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0514660.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            36934..38541
                     /locus_tag="ACL3F5_000826"
     CDS             36934..38541
                     /locus_tag="ACL3F5_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0514661.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWKYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAHEALEKGIPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            38706..38873
                     /locus_tag="ACL3F5_000827"
     CDS             38706..38873
                     /locus_tag="ACL3F5_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR0514662.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(38866..39648)
                     /locus_tag="ACL3F5_000828"
                     /pseudo
     CDS             complement(38866..39648)
                     /locus_tag="ACL3F5_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        12371 a         6671 c         8610 g        11996 t
ORIGIN      
        1 atacctttta tgaggctctt ttgtcttgtt cttgtttcaa ttgactataa atcgctataa
       61 gaaaaaatca ttttattggt ataaagaagt gattgaaagt aatggcgaaa cgttagataa
      121 ttagttcata aaaaacaagt ttgatcctca tctaaacttg tttttttaaa attgaaggat
      181 gattttgtag gatataagat gacattgact attcatgtat attataaagg tgatggagat
      241 agtgcaataa agtttgcaag agaaatgctt gatagtggcc ttgttgaaga aattagaaat
      301 caaaaaggta acttgaaata cgaatatttt ttaccaattg aaaaagaggg aactattctc
      361 cttattgatc agtggataaa tcaagaaact ttagataaac attatcaatc aaagacaatg
      421 cagaaaatct tagatttaag aaaaaaatat cacttgcaga tgcaagttga acgttatata
      481 gaagatgatt ctgggatgcc agaaagcgat aagtcgttta tagacacagg gaattagaat
      541 tattgtgaga gtttttgtag tttgaaagta ttgaaaatcg taaagatatc attacgagaa
      601 tacaagaaga tattgttcta tttccattaa aaattacttc tttccttaac aataaggaaa
      661 aagaatgcgt tttcatcttt tggtttgagg tttataataa gagtatcaaa gtcaggagga
      721 aaaaagatga ctacttttaa agatggattt ttatggggtg gtgctgttgc tgctcatcaa
      781 cttgaaggtg gatggcaaga aggtggcaag ggaattagtg ttgctgatgt tatgactgct
      841 ggtcgtcatg gagtagctcg tgaaattact ttgggagttt tagagggtaa atattatcca
      901 aatcatgagg cgatagattt ttatcatcgt tataaagaag acatagcact ttttgctgaa
      961 atgggattca agtgcttccg tacctctatt gcatggacac gtatctttcc aaaaggtgat
     1021 gagttagagc cgaatgaaga aggattacag ttttatgata atctttttga tgaatgctta
     1081 aagaatggta ttgaacctgt catcactcta tctcattttg aaatgcctta tcacttagtg
     1141 accgaatatg gtggttggaa aaataggaaa ttgattgatt tctttgctcg ttttgcagaa
     1201 gtcgtattta aacgttacaa agataaggtt aaatattgga tgactttcaa tgaaatcaat
     1261 aatcaagcga attatcagga agattttgca ccatttacta actcaggtat tgtatatgag
     1321 gaaggtgata atagagaagc aattatgtat caagcagcac attacgaatt agttgcttct
     1381 gcacgagctg taaaaattgg tcatgagatt aatccagatt ttcaaatagg ttgtatgatt
     1441 gcgatgtgtc caatttatcc agttacttgc aatcctaagg atatcttaat ggcaatgaaa
     1501 gctatgcaga agcgttatta ttttgctgat gtgcatgttt taggtaaata tcctgagcat
     1561 attttcaagt attgggaacg aaaaggtatt tcagttgatt ttactgacca ggataaagaa
     1621 gatttacttg gtgggactgt agattacatt ggtttcagtt actatatgtc ctttgctata
     1681 gactctcatc gtgaaaataa tccttatttt gattatcttg aaacagaaga tttagtgaaa
     1741 aataattatg ttaaggcttc tgaatgggag tggcaaattg atccagaagg tttacgttat
     1801 gcgttaaatt ggtttacaga ccactatcac ttaccactct ttattgttga aaatggtttt
     1861 ggagctatag atcaagttgc agcagatggt atggtacatg atgattatag aattgaatat
     1921 ctaggtgccc atattcgtga aatgaaaaag gctgtagttg aagatggtgt tgatttaatg
     1981 ggttatactc catggggatg tattgatttg gtttcagctg gtaccggtga aatgcggaaa
     2041 cgttatggtt ttatttatgt agataaagat gacaatggga agggaagtta taatcgttcc
     2101 ccgaaaaaat cttttggctg gtataaggaa gttatttcat ctaacggtga atcagtagaa
     2161 tagtataaac aaactgagat tattctcagt ttgtttagca tattgggatg acatatgatt
     2221 ggaagtattg cagcaatttt aacaacattt gcatttttac cacaagtttt tcgtatagtt
     2281 aagacaaagg acacaggatc tattgctcta ggtatgtatg ttatgcaagt tattggtatt
     2341 gcattgtggc ttgctcatgg tattcgtata ggagacttgc ctttgatttt agcaaatagt
     2401 gtttcatttc tactctcagg aataatttta ttttataaat tgaagtataa ataatttttt
     2461 tccatatcat ttaggaaaat gagggaattg tcattggaaa cgctttattt tataataaaa
     2521 atagataaca aataagccaa cttagcacag ctttgattgg atttaagaaa aggagaaaat
     2581 attatggcaa aagctttaat tatttgtgca gcaggaatgt cttcatcact tatggcacag
     2641 aaaacaacag agtttctaaa aggaaaaggg aaagatattg tagttgatgc tattagtgct
     2701 actgaaggag ggaaagctat cgcagcagct tttgatttgt atcttgtcag ccctcaaaca
     2761 aaaatgtact ttaagcaatt tgaagaggct ggttctaaag caggaaaacc agttgtacaa
     2821 atacctcctc aagcatatat tcctattcca atgggaattg aaaaaatggc taatttgatt
     2881 cttgagaata tttgatgaac acatgaaatg tcaataaata tttaggttaa gataaattgt
     2941 tttgagtttg atataaactg atttaagtgt ataatatgct tcaatatatg aaaacatacg
     3001 ttttaggagg gaatgaatgt gttaaacatt aaagagaaag atatccttca atttttaata
     3061 aaaaataagg aacgttttgt tacaagcaaa gaactggcag aatatttatc ctgttcagat
     3121 agaactgtcc gtaatgtact gaaattaatt gagaagacaa tgattattca aggagtccgg
     3181 ttgatttcaa aacaaggtca agggtatcaa atattttttg agaatcaagg cgcttaccag
     3241 gagtttagac aaacttatga actggaagaa gactatacga aaactgcggt ttcaaaaggt
     3301 gatgatcgtt tagtatttat cttaaataaa ttattatttg agcaagttcc agttcttttt
     3361 gatgatttag ctgatgaact ttacgttagc cgttcaacat tatctcatga tttcagaaag
     3421 atacgagtga tgttatcaga gtataatttg tccattgaga gtagggcgaa taaaggagtt
     3481 tatgtctcag gcgaggaacg tgataaacga cgttttatca taaattattt cctagagaat
     3541 caatttttta aaacaataca ttgctatgta aaatttaact tttttgatca aactgttcca
     3601 ttagaagaat ttgctagaat tgttttggat gaatgccaag aggccaacct aaaactatct
     3661 gattttgtac tacagaattt agtagttcac atagcattgt ctgtgattcg tttaaaatcc
     3721 ggatttgaaa taaaaaatat agactgtcag atgactgatg atgcaataga gagaaaggtt
     3781 gcccaaagaa ttctttctaa agtaagagaa gtaacaaatc aggaatttcc agttcaggaa
     3841 atagactaca ttactttgca tttgttagct aagagtcaac aatgtcaaaa aaatcagaag
     3901 aatatttctg aagaagtttt aaaaaaatct ttacttaaaa catttcagaa tttaggatta
     3961 gatgatatgt ataacttttc ttcagatttc caactaattg aaggattgat aactcatcta
     4021 atgacactac aagtacgttt agaaagccgg attaccttaa ataacccttt ggtagatgaa
     4081 attaaacaga attatagtga tatattcttt atgactagag aaattcttgc aaatatggac
     4141 aagttcttgg agtggacaat atcagatgat gaagtagcat atgtaagtct tcacttttta
     4201 gctgctatgg aacgtagcaa agagagtact aagtttaata ttcttgctat ttgtgcaaca
     4261 ggatttggtg cagcccaaat gttaagaaat cgtttggaaa cggagtttgg gaagcgagta
     4321 gaagttgttg atgtaatagg ctattatgaa ttgaatcaag aaaaacttaa aggaatagat
     4381 tttatagtgt cagctgttga tttatcaaat ctatattttc aaatcccagt ttttaaagtt
     4441 agtgtgtttc ttaagagtga tgagatggaa atgattagaa aagctatgga tcagatgcaa
     4501 gtttctagtt atgtacaatc atcaaagatt aacaaatttg aaaacaacgg ctttagacag
     4561 tattttagta aagaaaactt tttaatatgt actgaatcag acaaggtaaa tttacttgaa
     4621 aagatggttg agagtttatc tgttggtgaa tcaaatgagt ttgaacaatc tttactttat
     4681 ggaattaaac agcgcgaaga attaagttca gttgtttttt ctgaaaaaat tgcagttccg
     4741 catcctattc agtcctttgg tacagaggga aaggtttcgg ttgcaatttg taaagattcg
     4801 ttactctggg ataatcaaag ttcacatgtc cagctagtat ttcttctatc tccatcaata
     4861 tatgggaacg aaggtttggc aactgtgact aaaaagatag tctctctgac agagaatgat
     4921 gaattgcaaa atcagctaat atcttgcaat aactttgaag attttattaa catatttgag
     4981 aagataaaat aggaggttca tatgaatcaa gaggaactgc aggttgcagc atttgaaatt
     5041 atcctgcatt cgggaaatgc aaggtcagaa atacatgaag catttgcaaa aatgagagaa
     5101 ggtagttttg atgatgcaga aagtaaatta aatcaatcaa atgagataat tcttgaagcg
     5161 catcatgcac aaaccaaact cttgcaagaa tacgcaagtg gagtggaaat taaaattgaa
     5221 attatcatgg tacatgctca agatcattta atgaccacta tgacattatt agaagtagca
     5281 aaggaaatgt tagctcttta taagaaagtt aactaaatat gtgttgttat ataaggagga
     5341 aatgatatgg ataaaaaaga acgacaaaag attgaacaac aacgtcgaga gatggctcta
     5401 actaatactt ttttcaatcg atatcttctt ctacgttatt caatagcact cttctttttt
     5461 gggaatattt attggctttt gagtcagttt attagtccct cgcctattat tattttcccc
     5521 attatgctca tagtattttc tattttagca actgttgaac aatttaaact ctatggaaat
     5581 aggaaagaaa agttgggaat aacactaatg tttgttagaa tacaaatgct tatttcaata
     5641 ggattacttg ttttaacttg gacaagttgg tttaagaatc tttttccgat ttttgaaaat
     5701 aaccaagtag cacgtttatt tgtttttgta gttcttctat taggtttagt tctgagtttg
     5761 ttagacatta gaagaattaa aaaaatttat aaacgaacag ataaggctta tcaacaattt
     5821 gtccaattgg aaaagaactc acttagttta taatcctgat ctagtataat ttgtatttga
     5881 aaccagtctt tagaaagtaa aaattattat gttttattaa ggaggtctat ttatggatca
     5941 acaaaacggg ttgtttggtt ttcttgaaaa ccatgttatg ggaccaatgg gcaaacttgc
     6001 tcagtttaaa gtagtacgtg ctatcacggc tgcaggtatg gctgctgtac catttactat
     6061 tgtaggatca atgtttttgg tattcagtat tttgccacaa gctttctcat tttggccaat
     6121 tgtggcagat attttctctg cttcatttga taaattcaca tcactttaca tggttgcaaa
     6181 ctatgcgact atgggttctc tatctcttta tttcgttcta tcacttgcat atgaattgac
     6241 aaaaatttat gcagaggaag aagaactcaa tatgaatcct cttaatggtg ccttgcttgc
     6301 cttgatggct tttgtcatga cagtaccgca aatcattttt gatggtggaa tgatgaagac
     6361 tgtgacaagt ctaaaagaag gtgcagtaat tgcagatgga tgggcaatgg gaaatggagt
     6421 cgcacgtttt gggacaacag ggatttttac cgcaatcatt atggcaattg tgactgttct
     6481 tatttatcgt atgtgtgtta aacataattg ggttattaaa atgcctgaag ctgttccaga
     6541 aggagtttct cgtggattta ccgctttggt tccgggattt gttgttgcat ttgttgttat
     6601 ctttatcaac ggtcttcttg tagcaatggg aacagatatt tttaaagtca ttgcaattcc
     6661 atttggtttt gtatccaatc tgactaattc gtggattggt ttaatgatta tttatctatt
     6721 gactcaacta ctttggattg taggtatcca cggtgcgaac attgtttttg catttgttag
     6781 tccaattgct cttgctaaca tggctgaaaa tgctgctggc gggcacttcg ctgttgcagg
     6841 tgaattttct aatatgtttg taattgcagg tggttctggt gcaactttag gactatgttt
     6901 atatattgct tttacctcta aatctgaaca gcttaaagca ataggacgag catctgtagt
     6961 tccggcctta tttaatatta atgaaccatt aatttttgga ttacctatta tctataatcc
     7021 agccttggct ataccattta ttttagcacc aatggttact gctactattt attacgtagc
     7081 gaattctcta aactttatta agccaattat cgcacaggtt ccatggccaa ctccagtagg
     7141 gattggagct ttcttaggga cagcagatct tcgagctgta ttagttgctc tagtatgtgc
     7201 atttgcagca ttcctagtct atcttccatt catccgtgta tatgatcaaa aattggtgaa
     7261 agaagagcaa ggtatctaat aagtaaaaaa gtatactcga tgatagaatc catatagttt
     7321 aaataatgag cgttaacatt agcagtgaag aggtcttttt aagatattct tctctgcttt
     7381 ttcatatttt ttcgctatgt agggtatgaa gcaaaataga aagtagttcg aatagttgat
     7441 aaacagggaa ttgctgttat ttaaaaaaaa caataaagta aagtatgtta tcgtagaata
     7501 cgatacaata gtaaaaaagc aaaaagaatg cgttttatat ttgggtttga ggtttataaa
     7561 ataggataag catgctgaaa acttagatat gacaaacaaa ataaaatttt taaaagctac
     7621 atagaaacat ggtataatgt atctaaagga ggtagcatat gtccttagat atagataaag
     7681 aaaagatgac aatcatggga atagcttttg aaaaccgatc cgtttttaag agtgtttggt
     7741 atgctttaag tacaaatatg attgaaggat ggcgacctac ggttagtgat gttgaaaaat
     7801 tacgagatga agctcttgct ctggggatga cttaatgaag cgcaactgtt atgagtctta
     7861 tgactatgtt gatccggata atttatatac cgatccgggt tcttcagttc taagaaataa
     7921 gcaggaagga aaaaagcacg cgagcttgaa tatcgtatga ttgctagtaa gagtttgaaa
     7981 ttatttatca atcctatctt agttaatagt ttaaaagtag tttgtttcac aactgcataa
     8041 gcttagaaaa gttgaaaagt gataactctt taataaactc ttggtttgtt aaaagatatt
     8101 ttgtccacta cattttttca attgactatt atttgtcata gatataacag atagaacatt
     8161 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     8221 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
     8281 gacaagctag taaggttaga atactctcaa actggaagtt ttgaggatag aacgacacaa
     8341 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaacgta
     8401 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
     8461 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
     8521 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
     8581 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
     8641 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
     8701 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
     8761 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
     8821 tcggatgaat acttggattt aatagacaga tttgcaacag agaaaattcc attatctatc
     8881 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
     8941 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
     9001 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
     9061 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
     9121 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
     9181 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaggg gacacaaggc
     9241 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
     9301 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
     9361 ttttcagggg atactattat cagttggaat tccttaagat ttcaacccta ttttacagcg
     9421 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
     9481 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
     9541 cgattacata gttctagaag tccttttaat agtaaagaac cttggttttt ttcagaaaca
     9601 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ttatctatat
     9661 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
     9721 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
     9781 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
     9841 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
     9901 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
     9961 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    10021 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    10081 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    10141 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    10201 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    10261 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    10321 ttaaaagata gattgttaaa tcaattcatc aatgcgaaaa actctcatga cttaatgaat
    10381 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactatc
    10441 caaaactaat tgatataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    10501 tattcgttat cactggtcac attgaaaatg tgaaataagc acctacaaca tagactttac
    10561 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    10621 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    10681 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    10741 tgcccatcac gactaatgag aaacttagcg aaattccatt cgattcgttt tcctagtggg
    10801 ccagatttat ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    10861 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    10921 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    10981 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaaccg
    11041 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    11101 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    11161 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    11221 aagaataagc cctcaatatg atagaaaccg tttacaaata actttaaaaa tggtatgatt
    11281 taattaaacc ggtttacttt gttgctataa atctctaatt tgagatttag ttcctattga
    11341 ttttacaata tgtttattgg agtgtatata tgcaaacaaa aacaaagaag ctcattgtga
    11401 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    11461 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    11521 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagtccgt
    11581 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    11641 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    11701 aattaagggc agcgcttcac cgtatggttc ctattgaagc taagaaaaag tataaactgc
    11761 gtttcaagat taaaacagat aataaagtcg ggattgctaa agttcgtatc attgaggaaa
    11821 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    11881 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    11941 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagacc
    12001 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    12061 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    12121 cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca
    12181 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggatg
    12241 catacacagc ccgtttggat gactggaatg gcatcatcgc tgggaatcaa tactatgatt
    12301 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    12361 tatctagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    12421 aaatgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    12481 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcta
    12541 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    12601 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    12661 tctctgatga ggaaattaaa aaatatacag atgtaattga aaaatttgta ccagaccccg
    12721 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    12781 tgggaagagt aaaagtaata gctggtttac tgcgtaaaga tgatcaagaa atttcttcta
    12841 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    12901 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    12961 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    13021 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    13081 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    13141 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    13201 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    13261 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    13321 caggagtcgc aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa
    13381 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    13441 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    13501 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    13561 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    13621 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    13681 caactatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    13741 taaaggataa gattgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    13801 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    13861 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    13921 tagaatcgtt cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    13981 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    14041 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    14101 atggctatat gctaattcct aacgtggatc gtgccacctt caatcaaatg ataaaagagt
    14161 tagaaagtag cctcatcgac aataacgaaa cccttcagtc tgtttatgat gctaaacaag
    14221 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    14281 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    14341 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    14401 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    14461 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    14521 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    14581 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    14641 atcttcggat ttttctttta aaaaaggata agttgatact tatccttttt tacttcatta
    14701 ttatgtgact atagcgtttt gaaactagaa tagaacgtta taactgctaa aagatttcta
    14761 taaattcatt tgattttcct aatcaatttg ttcgtatcct atttcactcc actatataag
    14821 tccgtctcgc tccgtgaggt gcgcgtcgaa ggttatacca aaaaaactcc aaacgcgata
    14881 caataaaggt attcaatcca attgtaaagc gaaaggagaa aaaatatggc acaaaagact
    14941 catagtttat catacacaaa gtggatgtgt tctatcatat tgtgttcacc cctaagtata
    15001 gacgaaaagt catctataat caatatagaa gtagtttagg cgaaatattt catcgcttgt
    15061 gtagttataa aggtgttgaa atgatcgagg gtcacttaat gccagaccat gtacacatgt
    15121 tagtcagtat tccgtcgagg ctaagtgttt caagttttat ggggtattta aaaggcaaaa
    15181 gtgcactcat gatgtttgac aaacacgcca atctcaagta caagtttggg aatcggaatt
    15241 tctgggcgga aggttattat gtaagtccag tagggcttag tgaagccaca attaagaaat
    15301 atagtcaaga ttaaagaaat tatcgagtgg atgatttctt cacgagtatg aaaatttgag
    15361 aactagtaaa gtatgatata tagtaaaatg aaataagaat aggacaaaat cgatcaggac
    15421 agtcaaatcg atttttaaca atgttttaga agtagaggta tactattcca gtttcaatct
    15481 actatagcac tagataaatt gagtgtaaaa gaatatgagg atccctttag ggatagtggt
    15541 aagtaatacc aaagtctctt aaagaggcaa gtgacgagtc aagagcaata aggcttgaac
    15601 aacgtgaaag ccagcgtctt taggcgctgg ctgatgattt gggcttatag ctctgagata
    15661 aaccacccgt tagacgggta gttatgattt tatctgagtg taatatactg ttgggcaatc
    15721 tcgctgatgc ggtcaaagtt gccttgggaa gcgagtttat tgagttcgcc accaattcca
    15781 acggcatctg caccagcagc gaaccattga gggatgttgt ttaggccgac tcctccggtt
    15841 accattacgg aaacttgtgg gatcggtgcc ttgactgcag agatatatgc tggactgaga
    15901 gtactacctg ggaagagttt gatgatttca ctaccggctt caagtgcagt cgtgatctct
    15961 gtgagggtaa tacagcctgg aatgtacggt gtgctgtaga gattgcacat tttcgcagtt
    16021 tcagcatgga aagatggaga aacaacgtaa tttgctccag ctagaatggc atctctagca
    16081 gttacggcat caagcacagt acctgcaccg atacaaacac tctgatcgtc ctgatacaag
    16141 tctacaagtt ccttgatgat ttgtcctgca tactgattgg tataggcgat ttcaatagct
    16201 ttgataccgc ccttgataca agcaatcgag gcttgtagtc cttcttcctt tgtatttcct
    16261 cgaatgacag cgacaatttt ctgttttttt agttcaataa tcgtatctga tttggtcatg
    16321 taattctcct aacgaatgat atcttgtgca tttgccagta aattttcaat actagttgcg
    16381 gaagtggaga gatggtctcc tggaagagtg catttgagag ttgcgctcgc aactgcaaag
    16441 tcaatggtag tttttaggga ggaatgatgg agtagttggt aaagggcacc agatataaag
    16501 gcatccccgc taccaattcg ttgatagact gcagttttta gttggacaga ctcttcaaat
    16561 cgttcttcca gagcataggc ttgatagaca tttttgtctt gctcatcact agatcggagg
    16621 gtatggaaaa tggccttgaa accataggct tcttttaaaa gtcgcatgcg attttccacc
    16681 tcttctaggc tagcactgtc tcttggaaac atctctagat tttggtcatc aatcatgaga
    16741 ggatcaatac cgaagcaata gtcagtaaaa cgtgcaaact tagaaaattc atacttggct
    16801 tctaggactg aaatcatctt tgttctcaga ttgagatcca ttgaaacgac aattcctcgg
    16861 cgcttggctt cttccaagag taggagaagg atcgcacgga cctcttgacc gatagctatg
    16921 gtgattccac taaaatgaaa atggctaatc ccctgaaaga gagaatccat atctagcatg
    16981 tttggccgaa tctggctgat actcgtatgc ttacgatcgt agaaaacttc actttgacga
    17041 caaccaaagc cgttctccaa atagtagagg ccgattcgat cgccaagccg acagattgaa
    17101 ctggtatcga tttggtgctg tttcaagaat gtgagaaaac gatctccaat ctcgttggca
    17161 gggagtgcgg taaagacttt cgttgagata cccagggctt gcaaattaca agcgatgtta
    17221 atttctgatc cgccaaaata agtcgaactg gcaacatgat cgccgatact ggtggcatct
    17281 aatggtgaga ttcgaattaa tggttcgcca aacagtaata ttttcgtcat ccattagttc
    17341 ctttctggtt tagaatagct ttacttggct aatacttctt tcaaataagc agcgacttca
    17401 tcatcttggc agttttcaaa gaagtattct tggaagtatt tgccagagat ggtgtctttg
    17461 aggaagtctt ggtcgattgt tttaaggatg gtcatcaaat cattgtgggt gatttgtttc
    17521 acctcgttta agatacgagc gttacgttgt tcagggatta cacgttctct tgggtagcca
    17581 ccgcccattt cttcagcaaa taagcgttca aacatcaatt tgagggtcag ttctgccccc
    17641 cagccaaatc ctttggcata agggatagac aaggcgttac caccattgat ttgagaataa
    17701 aggtaagcgt cagttgggtc cactgctaga ccacagacaa caccagggaa gctgtttaaa
    17761 gcaagcatag cccctacacc cgtaccacag ccggtaacaa caaagtcaac tgcctttgta
    17821 tttaaaagga tggcagccat tagtccgttc tgcacataag ttaattgact ttctccttct
    17881 tctccacgca taccatagtt aaataattgg tagccttttt tatctgtcgc ttcttttaga
    17941 ctatcgtaaa taatgtgatt cttgctagct tgactatttt cattgattaa tgcgattttc
    18001 ataagatctt ctttctattt ttactcaggt tgttttccga tgtaggctaa gataccgcca
    18061 tctacatata ggatgtggcc attgacaaaa ttgctggcat cactagcgag aaagacagca
    18121 gggcccatca aatcttcagt atttccccaa cgtgcagcag gtgtttttgc aatgatgaac
    18181 tggtcaaatg ggtggcgaga accatcttct tgcaattcac gaagaggtgc tgtttgagga
    18241 gtggcaatat aacccggtcc aattccgtta cattggatat tggctccacc gtattcagac
    18301 gcaatgttgc gggtcaacat tttcaagccc cctttagcag cagcataagc gctaactgtt
    18361 tcacgtccca gttcgctcat catcgaacaa atattgataa tctttccatg ccctttcttt
    18421 atcatagaag gaataactgc ctttgaaacg ataaatggtg cgtttaagtc aatatcgatg
    18481 accttacgga aatcagcggc gctcatttcg cacattggaa ctcggcggat aataccagcg
    18541 ttattaacga ggatgtcaat gacaccaacc tcttgttcga tttgcttgac catggcttgg
    18601 ataccgtcct cgtctgtcac gtcacagaca tatccatggg cttggatgcc aacttcacga
    18661 taagcttcaa tccctttatt gaccagatct tgattgatat cgttaaagac aatagtagcg
    18721 ccggcttcag cgtaggattt ggcaatagca aatccaattc cataagaagc gccggtgatg
    18781 agagcaattt ttccttttaa agaaaactgc tcaattgaga atgatgtatt tgtcatttga
    18841 tacttccttt caaatttgtt aagacttctc tataaccaaa ttatattcta gtaaaccggt
    18901 tttgtcaata aataaatatt tttatttatg aaaaggtttg ttttcctaaa aaaacggaag
    18961 attttgaaat ttctgtctat taaaatggtt aaaaagataa tgaaagcgct aatatttttt
    19021 taaaaaaact attgacaaga taaaaataaa ggattacaat ggggaatata aagtaaaccg
    19081 gtaaacctaa aagaaaggag aaaagatgaa aattgtactt gtagggcatg gacattttgc
    19141 tacagggatt tatagttctt tacaattgat tgcaggtaat caagaaaatg tggaggcgat
    19201 tgactttgtg gaaggaatgt cagcagatga actcaagcaa aaaatcttac ttgcaatttc
    19261 aaatgaagaa gaagttttaa tcctaagtga tctcttggga ggatcgccat tcaaggtttc
    19321 ttctaccata atgggagaaa atccagccaa gacaatgaat gttctctcgg gtttgaactt
    19381 agccatgtta atggaagcag tttttgctag aatggctcat agctttgatg aggttgttaa
    19441 taaatcagta gtggcggccc agggcggagt cgtaaatggt aaagaattgt tttcaacgga
    19501 tgcagaggaa gaggaagaag atttcgaatc gggtatttaa agggtgaaag aatgataaaa
    19561 aaggttacga ttgaagaaat aaaatcgcct gagcgcttct tagaagtacc acttctgacg
    19621 aaagaagaag tcggccaggc aatcgataag gttattcggc agttagaact caaccttgac
    19681 tatttcaagg aagatttccc gacgccagct acctttgata atgtctatcc aatcatggat
    19741 aacacggaat ggaccaatgg tttctggaca ggagaactgt ggttggctta tgaatacagt
    19801 caacaggatg catttaaaaa catcgctcat aaaaatgttc tttctttcct ggatcgtgtc
    19861 aataagagag tagaattggc tcaccatgat ctcggcttct tgtacacacc gtcttgtatg
    19921 gctgaatata agataaatgg agatggagag gctagagaag cagccttgaa agctgcagat
    19981 aagttgattg aacgctatca agaaaaaggt ggttttattc aagcttgggg agacttgggc
    20041 aagaaagagc attaccgttt gattatcgat tgcttgctca atatccaact cttattcttt
    20101 gcttatcaag aaacaggcga tcaaaaatac tacgatattg cagaaagcca tttctatgct
    20161 tcagctaata atgtaatccg tgatgacgct tcgtccttcc acaccttcta ttttgatcct
    20221 gagacaggtc aaccctttaa aggtgtaacg agacaagggt atagtgatga ttcatgctgg
    20281 gcacgtggtc agtcatgggg agtttatggt attcctttga cttatcgtca cttaaaagac
    20341 gagtcctgct ttgacttgtt taagggtgtg accaattatt tcttgaatcg tctgccaaaa
    20401 gatcatgtgt cctattggga tttgattttt aatgatggta gtgatcaatc acgagattct
    20461 tcagcaacag ctatcgccgt ctgtgggatt catgaaatgc taaaacatct cccagaggtg
    20521 gatgctgaca aagatattta taaacatgct atgcatgcca tgcttcgttc cttgatcgaa
    20581 cattatgcaa atgatcaatt tacccctggt gggacaagtc tcctccacgg tgtgtactca
    20641 tggcattcag gtaaaggagt ggatgaaggc aatatctggg gtgactacta ttacctagaa
    20701 gcccttatcc gtttctacaa agactggaac ctatattggt aggaggagaa atatgacaat
    20761 gccaaatatt attatgaccc gtatcgatga acggttgatt catggacaag gacaactttg
    20821 ggtaaaatac ctaggttgta atacggtcat tgttgccaat gacgaagtaa gcacggacaa
    20881 gatgcaacaa actctgatga aaacagttgt gccagactca gttgccatgc gtttcttccc
    20941 tttgcaaaag gtgattgata tcattcacaa ggctaatcct gctcaaacga tctttatcgt
    21001 tgtaaagaat gtgaaggatg ctttaacctt ggtagaaggt ggtgtcccta tcaaagaaat
    21061 caatattggg aacattcaca atgctactgg taaagagcaa gtgacacgct ccatcttcct
    21121 gggtgaagag gacaaggcag ccctcaagga attgaaccaa actcatcaag taacatttaa
    21181 tacgaaaaca actccaacag gaaatgatgg agctgttcaa gtcaacatta tggactatat
    21241 ttaaaagagg agatcgttat gtcgattaat gtatttcaag cgattttaat tggattatgg
    21301 acagctttct gttttagtgg aatgctgtta ggaatttaca ccaatagatg tattgttctg
    21361 tcatttggtg tcggaattat tctaggtgat ctgcctactg ctcttgcaat gggagctatt
    21421 ggtgaattgg cttatatggg attcggtgtt ggtgctggag gtactgttcc accaaaccca
    21481 atcggacctg gtatctttgg taccttgatg gctatcacta gtgctggtaa agtcagtcca
    21541 gaagcggctc ttgccctctc tactccgatt gctgtggcga ttcaattctt acaaactttc
    21601 gcctacactg tacgtgctgg tgcgcctgag acggcgatga agcacttgaa aaaccataat
    21661 ttgaagaaat tcaagttcac tctaaatgca acaatttggt tgtttgcctt tattggattt
    21721 accttgggtt gcttgggtgc cctttcaatg gataccttgt tgaaactcgt agactacatt
    21781 ccaccggtat tgcttacagg tttgacagtt gctggtaaaa tgctcccagc tatcggtttt
    21841 gcgatgatct tgtcagtgat ggctaagaaa gagttgattc cctttgtctt gttgggatat
    21901 gtttgtgcag cttatctaaa catcccaaca attggtattg caattgtagg tactatcttt
    21961 gctttgattg aattttataa caagccaaaa acagcggatc atgtggtaga ggaggaagca
    22021 cacgatgact ggatctaaca aattaacaaa acgtgattat cttaaaacgt ctttgcgggc
    22081 attcttttgt caaaatggat ttaactatag taactatcaa gggttgggat atgccaatgt
    22141 gatgtatcct gctttgaaaa aacactatgg agaggatcag gaaggtttct accaagcctt
    22201 ggaagaaaac tgtgaattct ataataccaa cccacacttc ctgcctttta ttaccagctt
    22261 gcatcttgta atgttggaaa atggccgtcc ggcaaaagaa acacgtagca tcaagatggc
    22321 cttgatggga ccattggcag gtattgggga ttctctttct caattctgtt tagctccatt
    22381 gttctcaacc atcgcagctt cgtttgctca agaaggcttg gttgtcggtc caatcttgtt
    22441 cttccttgcg atgaatacga ttttaacagc gattaaattg tcaactggtc tgtatggata
    22501 caaactagga acaactgtga ttgataaact aagcgaacag atggcaacga tttctcgtat
    22561 tgccaatatt atcggtgtaa ccgtaattgc tggtttggca gcgacatctg ttaagattat
    22621 ggtgccgatt acctttgctg caggggaagt taaagcagac gctaaacaaa gtatcgtaag
    22681 tattcaggga atgcttgata aggttgctcc agctcttcta ccagccctat ttacactttt
    22741 agtttactac ttgatcaaag aaaagaaatg gacaacatat aaactcgtta ttttaacagt
    22801 tatcatcgga attatcggaa gctggcttaa gattatagct taatggatac aacattgttt
    22861 tatggaatag tgattgtctt ggcagtgagt ccccttttac tgtcaagctt tcattctatt
    22921 cgtcagcaaa agttgcttcg caaacagatg gagcaacgac aagagtattt agcttcttta
    22981 acatctggtg atgaagtgtt gttattgtct ggaattcatg gaaaaatcat ttctatcaaa
    23041 gatgacttgg tctccttgca gattgcaaaa ggtgtggtca tctatgtaga aaaggaaagt
    23101 gtaatgggaa agacaaaaga actgcttttt aagtagttct ttttctggta atagataatg
    23161 aaagaagaaa gaagacaatt ttttgaaaga atcgatggaa accaatgtcg tgattatatc
    23221 ttgccccact gttcaaaaga ctatgagaaa gtcaagagtt cccttgaacg cttgatggac
    23281 aatcgtttta tgtttgatag tccttgggat atggagcctt gttcaaaaat ccatcaaatc
    23341 cagccgatgg tatgggatca agtatttgaa gatgatccag aatgggctta tatgctcaat
    23401 cgacaagaat atctcttgca gtttatgata gggtatctgg tagaaggaga taagagctat
    23461 attcaaaagt gcaagttctt tctatttgat tggattgagc aggtgagaga attttctcct
    23521 caatccttga tgactagaac cttggatacg ggtattcgtt cctttacttg gttgaaacta
    23581 ctcttgctcc tcttgaaatt tgacttgcta gaggagaaag aactagagaa aattttggtc
    23641 agtctagaaa agcagattga ctttatgaaa agccactatc gcgccaagta cacccttagt
    23701 aactggggga ttttacaaac aattccgatg cttgctatct attatttctt ttcagataag
    23761 atggatctag aagaagctta ccattttgct tcagaggagt tgaaacagca aattgagaca
    23821 cagattttag gagatggaag ccagtttgaa cagtcgattc tctatcatgt agaggtttat
    23881 aaagccttgc tggatttgtg tctcttgctt ccagacttgc aagatagtta ccgagagttg
    23941 ctggaaaaga tggcgaccta tattcaaatg atgacaggct tagatggacg aactttggct
    24001 tttggtgata gcgattctac agaaacgaca gaaattttga gcctgtctgc tgtggttttg
    24061 aacaaggaag accttcttaa cggtctggat gttaaagtcg atttgcttag cctcttgttc
    24121 ctggggcgag aaaaggtcaa gcgactgcag gaatttgaaa ggagagcttg gcagcctaag
    24181 tccatgatct ttgaagactc tggacatgtc tgcattaagg atgaacatcg ttatctattt
    24241 ttcaaaaatg gtccgctagg aagtgcccat agccatagtg acgagaatag tttttgctta
    24301 cagtatcaag gccaacctat tttcatagat gctgggcgtt attcttatcg ggagatatat
    24361 gaacgttatc tcttaaagag tgcttggagt cattcgacct gcattgtaga tgggaaagct
    24421 ccggaaagaa tcacgggatc ctgggaatat gaatactatc ctcactccct gttttgtcac
    24481 cataaagaaa gggagggagt gcattatatt gagggggctt attggtcagc agaacctgat
    24541 ttgccttatc ttcacaggag aaaaatcctc atgttggtag aggatgtctg gctcttggta
    24601 gatgacatca ggtgtcaagg tcagcatgag gcgttgactc agtttatcct tgacaaggat
    24661 gtgacctatc aagatgggaa aatcaatcag ttgagactat ggagtgaagt tgattttgat
    24721 ttggaagata ccatcatttc tcctaaatac aatgagcttg aaagaagtag caaactcacc
    24781 aagcgccaat tctttgagaa tcagatgctg gattatacca tcattgcgca tgagagtttt
    24841 gaaatcatcc gtcattctgt ctaccagaca gatgatcgtg aagtggaaaa tgctctggct
    24901 tttgaagtga aaaatgacga aacagacaag ctgattctgt tattaagcga ggatattggt
    24961 gtaggtgaaa aattgtgcct cgttgacgga acaaaaatgc gtggaaaatg tctagtatat
    25021 gataaaataa atgagagaat gattcgcttg cagtgctaga aataggcatt ttgaatagtg
    25081 aatatgttat aataagtatt agtaggaggt gttttagatt ggagaagaaa ctgaccataa
    25141 aagacattgc ggaaatggct cagacctcga aaacaaccgt gtcattttac ctaaacggga
    25201 aatatgaaaa aatgtcccaa gagacacgtg aaaagattga aaaagttatt catgaaacaa
    25261 attacaaacc gagcattgtt gcgcgtagct taaactccaa acgaacaaaa ttaatcggtg
    25321 ttttgatcgg tgatattacc aacagtttct caaaccaaat tgttaaggga attgaggata
    25381 tcgccagcca gaatggctac caggtaatga taggaaatag taattacagc caagagagtg
    25441 aggaccggta tattgaaagc atgcttctct tgggagtaga cggctttatt attcagccga
    25501 cctctaattt ccgaaaatat tctcgtatca tcgatgagaa aaagaagaaa atggtctttt
    25561 ttgatagtca gctctatgaa caccggacta gctgggttaa aaccaataac tatgatgccg
    25621 tttatgacat gacccagtcc tgtatcgaaa aaggttatga gcattttctc ttgattacag
    25681 cggatacgag tcgtttgagt actcggattg agcgggcaag tggttttgtg gatgctttaa
    25741 cagatgctaa tatgcgtcac gccagtctaa ccattgaaga taagcatacg aatttggaac
    25801 aaattaaaga atttttacaa aaagaaatcg atcccgatga aaaaactctg gtatttatcc
    25861 ctaactgttg ggccctacct ctagtcttta ccgttatcaa agagttgaat tataacttgc
    25921 cacaagttgg gttgattggt tttgacaata cggagtggac ttgcttttct tctccaagtg
    25981 tttcgacgct ggttcagccc tcctttgagg aaggacaaca ggctacaaag attttgattg
    26041 accagattga aggccgcaat caagaagaaa ggcaacaagt cttggattgt agtgtgaatt
    26101 ggaaagagtc gactttctaa aatgaaggaa aatgacttgc aatctctgtt aagaaataaa
    26161 ataatcccac ctagaacaag ctaggtggga ttatttgcct atgaaatgag aaattatggg
    26221 agcaagctcc taaatcaact gtttttgatc tacttcttta actacttgat aaaagttata
    26281 gaagtaggcc aaacttgaaa tgatggttac gactaggaat attgaaaatt tccattggat
    26341 agggttggtt aaaagttgtg gaaaggatat gaggagaaag aagagggctg cgttgaggac
    26401 aggtatccgt tttgattgta ttttctcaag tcctttattg agcgcaggaa gaaagaggag
    26461 taggagtagt aaaactgtat gagaaacagc tcctgaaata agggcaaaga aaaggaaaat
    26521 actgataaaa acatgaatga tcagtagtct agctagtgat ttcataaggt acctcctaat
    26581 cctggtcttt tttagctctt gcaatacgaa gtgagtcgac aatatgtatc atcactccga
    26641 aaaagaaagc tcccagtata gttttaaaaa tatgttttgt atttagaaga gaactgataa
    26701 aatttggatt ttcacttgtt agggtatcaa tgagtggaat tataaaaaat atcactgttc
    26761 cataaatcga acctgctttc agaccaggat aacgtaactg tttcttttct tttttcatga
    26821 gtttgctcct tttttaaaaa tcttcctccc aaaagagact gttgaggtca gtttggaggc
    26881 tgcgggcgag attgagacag agttccaagg ttggattgta cttgtcgttt tcaatcatat
    26941 tgatagtctg tctcgagaca ccgatatcct tggcgagttc gagctgggaa atacccaatt
    27001 ccttgcgaaa ttctttcaca cgattcatct ggtctccttt ctgatttatg tcgtatatat
    27061 ttgactatat tatagtcttt taaacataaa gtgtcaagta tttttgacat attttttgaa
    27121 gaaatagtag tctccttgtc ctatttgtct gacaagtgca agctggtcgg atttgtggta
    27181 aaatagataa gatatgacaa aagaatttca tcatgtaacg gtcttactcc acgaaacgat
    27241 tgatatgctt gacgtaaaac ctgacggtat ctacgttgat gcgactttgg gtggagcagg
    27301 ccatagcgag tatttattaa gtaaattaag tgaaaaaggc catctctatg cctttgacca
    27361 ggatcagaat gccattgaca atgcgcaaaa acgcttggca ccttacattg agaagggaat
    27421 ggtgaccttt atcaaggata acttccgtca tttacaggca cgtttgcgcg aagctggtgt
    27481 tcaggaaatt gatggaattt gttatgactt gggagtgtct agtcctcaat tggaccagcg
    27541 tgagcgtggt ttttcttata aaaaggatgc gccactggac atgcggatga atcaggatgc
    27601 tagtctgaca gcctatgaag tggttaatca ctatgactat catgatttgg ttcgtatttt
    27661 cttcaaatac ggtgaggata aattctctaa acagattgcg cgtaagattg agcaagcgcg
    27721 tgaagtgaag ccgattgaga caacgactga gttagcagag attatcaagt tggtcaaacc
    27781 tgccaaggaa ctcaagaaga agggtcatcc tgctaagcag attttccagg ctattcgaat
    27841 tgaagtcaat gatgaactgg gagcggcaga tgagtccatc cagcaggcta tggatatgtt
    27901 ggctctggat ggtagaattt cagtgattac ctttcattcc ttagaagacc gcttgaccaa
    27961 gcaattgttc aaggaagctt caacagttga agttccaaaa ggcttgcctt tcatcccaga
    28021 tgatctcaag cccaagatgg aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga
    28081 gttagaagcc aataaccgct cgcactcagc caagttgcgc gtggccagaa aaattcacaa
    28141 gtaagaggga aaaagatggc agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa
    28201 cttaaacggt tttcgcgtgt ggaaaaagct ttttactttt ccattgctgt aaccactctt
    28261 attgtagcca ttagtattat ttttatgcag accaagctct tgcaagtgca gaatgatttg
    28321 acaaaaatca atgcgcagat agaggaaaag aaaaccgaat tggacgatgc caagcaagag
    28381 gtcaatgaac tattacgtgc agaacgtttg aaagaaattg ccaattcaca cgatttgcaa
    28441 ttaaacaatg aaaatattag aatagcggag taagatatga agtggacaaa aagagtaatc
    28501 cgttatgcga ccaaaaatcg gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt
    28561 ctgagtttat tatctgtctt tgtttttgcc atttttttag tcaattttgc ggtcattatt
    28621 gggacaggca ctcgctttgg aacagattta gcgaaggaag ctaagaaggt tcatcaaacc
    28681 acccgtacag ttcctgccaa acgtgggact atttatgacc gaaatggagt cccgattgct
    28741 gaggatgcaa cctcctataa tgtctatgcg gtcattgatg agaactataa gtcagcaacg
    28801 ggtaagattc tttacgtaga aaaaacacaa tttaacaagg ttgcagaggt ctttcataag
    28861 tatctggaca tggaagaatc ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa
    28921 gtttcctttg gagcaaaggg aaatgggatt acctatgcca atatgatgtc tatcaaaaaa
    28981 gaattggaag ctgcagaggt caaggggatt gattttacaa ccagtcccaa tcgtagttac
    29041 ccaaacggac aatttgcttc tagttttatc ggcctagctc agctccatga aaatgaagat
    29101 ggaagcaaga gcttgctggg aacctctgga atggagagtt ccttgaacag tattcttgca
    29161 gggacagacg gcattattac ctatgaaaag gatcgtctgg gtaatattgt acccggaaca
    29221 gaacaagttt cccaacgaac gatggacggt aaggatgttt atacaaccat ttccagcccc
    29281 ctccagtcct ttatggaaac ccagatggat gcttttcaag agaaggtaaa aggaaagtac
    29341 atgacagcga ctttggtcag tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg
    29401 acctttgatg cagatacaaa agaaggcatt acagaggact ttgtttggcg tgatatcctt
    29461 taccaaagta actatgagcc aggttccact atgaaagtga tgatgttggc tgctgctatt
    29521 gataataata cctttccagg aggagaagtc tttaatagta gtgagttaaa aattgcagat
    29581 gccacgattc gagattggga cgttaatgaa ggattgactg gtggcagaat gatgactttt
    29641 tctcaaggtt ttgcacactc aagtaacgtt gggatgaccc tccttgagca aaagatggga
    29701 gatgctacct ggcttgatta tcttaatcgt tttaaatttg gtgttccgac ccgtttcggt
    29761 ttgacggatg agtatgctgg tcagcttcct gcggataata ttgtcaacat tgcgcaaagc
    29821 tcatttggac aagggatttc agtgacccag acgcaaatga ttcgtgcctt tacagctatt
    29881 gctaatgacg gtgtcatgct ggagcctaaa tttattagtg ccatttatga tccaaatgat
    29941 caaactgctc ggaaatctca aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct
    30001 agtctaactc ggactaacat ggttttggta gggacggatc cggtttatgg aaccatgtat
    30061 aaccacagca caggcaagcc aactgtaact gttcctgggc aaaatgtagc cctcaagtct
    30121 ggtacggctc agattgctga cgagaaaaat ggtggttatc tagtcggggt aaccgactat
    30181 attttctcgg ctgtatcgat gagtccggct gaaaatcctg attttatctt gtatgtgacg
    30241 gtccaacaac ctgaacatta ttcaggtatt cagttgggag aatttgccaa tcctatcttg
    30301 gagcgggctt cagctatgaa agactctctc aatcttcaaa caacagctaa agctttggag
    30361 caagtaagtc aacaaagtcc ttatcctatg cctagtgtca aggatatttc acctggtgat
    30421 ttagcagaag aattgcgtcg caatcttgta caacccatcg ttgtgggaac aggaacgaag
    30481 attaaaaaca gttctgctga agaagggaag aatcttgccc cgaaccagca agtccttatc
    30541 ttatctgata aagtagagga agttccagat atgtatggtt ggacaaagga gactgctgag
    30601 acccttgcta agtggctcaa tatagaactt gaatttcaag gttcgggctc tactgtgcag
    30661 aagcaagatg ttcgtgctaa cacagctatc aaggacatta aaaaaattac attaacttta
    30721 ggagactaat atgtttattt ccctcagtgc tggaattgtg acatttttac taactttagt
    30781 aggaattccg gcctttatcc aattttatag aaaggcgcaa attacaggcc agcagatgca
    30841 tgaggatgtc aaacagcatc aggcaaaagc tgggactcct acaatgggag gtttggtttt
    30901 cttgattact tctgttttgg ttgctttctt tttcgcccta tttagtagcc aattcagcaa
    30961 taatgtggga atgattttgt tcatcttggt cttgtatggc ttggtcggat ttttagatga
    31021 ctttctcaag gtctttcgta aaatcaatga ggggcttaat cctaagcaaa aattagctct
    31081 tcagcttcta ggtggagtta tcttctatct tttctatgag cgcggtggcg atatgctttc
    31141 tgtctttggt tatcaagtgt atctagggat tttctatatt gtcttcgctc ttttctggct
    31201 agtcggtttt tcaaacgcag taaacttgac agacggtgtt gacggtttag ctagtatttc
    31261 cgttgtgatt agtttgtctg cctatggagt tattgcctat gtgcaaggtc agatggatat
    31321 tcttctagtg attcttgcca tgattggtgg tttgctcggt ttcttcatct ttaaccataa
    31381 gcctgccaag gtctttatgg gtgatgtggg aagtttggcc ctaggtggga tgctggcagc
    31441 tatctctatg gctctccacc aagaatggac tctcttgatt atcggaattg tatatgtttt
    31501 tgaaacaact tctgttatga tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat
    31561 tttccgtatg acgcctgtac atcaccattt tgagcttggg ggattgtctg gtaaaggaaa
    31621 tccttggagc gagtggaagg ttgacttctt cttttgggga gtgggacttc tagcaagtct
    31681 cctgacccta gcaattttgt atttaatgta agaatggcat cctgatgttt cagggtgttt
    31741 ttgtatttaa atacacaatg aaaatcaaag aacaaactag aaagctaact ttaggctgct
    31801 caaaatatag tagattgaaa ctagaatagt acacatctac ttctaaaata ttgttagaaa
    31861 tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta tacagttttg
    31921 agatggttga tagaactgac gaagtcagct caaaacatgg ttttgaggtt gtagataagg
    31981 agaagctgat gtggtttgaa gaggttttcg aagagtgtaa aaaaatattg gtcagttaaa
    32041 gccaaaacta ttgacctttt ctgaccaatg tagtatatta tgaacgtaag gtaaatgaaa
    32101 gccttactag aacacttatt taaagtaaaa tagaaagagg tgggtctatg tttcatctag
    32161 aaatcttcag aagtaaagat ggtctactcc tgcttgaaaa agaaaaacca gaaatagtac
    32221 gtagggtagc ggtttaacta gtctaaattt tttaaaacaa tggtcaaaga tagtcaatat
    32281 cagtaatcat aactaagtaa acaaaaagag gtaaagaata tgaataacaa ctttaataat
    32341 tttaataaca tggatgattt atttaaccaa ttgatgggtg gtatgcgagg atatagttct
    32401 gaaaatcgcc gttacttaat taatggacgc gaagtcacat ctgaggaatt tgctcactat
    32461 cgtgcgactg gtcaattacc aggaaatgca gaaactgatg tgcaaatgcc acaacaggca
    32521 tcaggtatga aacaagacgg tgtccttgca aaactaggtc gaaacttgac agcagaagcg
    32581 cgtgagggca agttggatcc tgttatcgga cgaaacaagg aaattcaaga aacatctgaa
    32641 atcctctcac gccgcaccaa gaacaatcct gttttggtcg gagatgcagg tgttggtaag
    32701 acagcagttg tcgaaggtct agcgcaagcc attgtgaacg gagatgttcc tgctgctatc
    32761 aagaacaagg aaattatttc tattgatatc tcaggtcttg aggctggtac tcaataccgt
    32821 ggtagctttg aagaaaatgt ccaaaactta gtcaatgaag tgaaagaagc agggaatatt
    32881 atcctcttct ttgatgaaat tcaccaaatt cttggtgctg gtagcactgg tggagacagt
    32941 ggttctaaag gacttgcgga tattctcaag ccagctctct ctcgtggaga attgacagtg
    33001 attggggcaa caactcaaga cgaataccgt aacaccatct tgaagaatgc tgctcttgct
    33061 cgtcgtttca acgaagtgaa ggtcaatgct ccttcagcag agaatacttt taaaattctt
    33121 caaggcattc gtgacctcta tcaacaacat cacaatgtca tcttgccaga cgaagtcttg
    33181 aaagcagcgg tggattattc tgttcaatac attcctcaac gtagcttgcc agataaggct
    33241 attgaccttg tcgatgtaac agctgctcac ttggcggctc aacatccagt aacagatgtg
    33301 catgctgttg aacgagaaat cgaaacggaa aaagacaagc aagaaaaagc agttgaagca
    33361 gaagattttg aagcagctct aaactataaa acacgcattg cagaattgga aaagaaaatc
    33421 gaaaaccaca cagaagatat gaaagtgact gcaagtgtca acgatgtggc tgaatctgtg
    33481 gaacgaatga caggtatccc agtatcgcaa atgggagctt cagatatcga acgtttgaaa
    33541 gatatggctc atcgcttgca agacaaggtg attggtcaag ataaggccgt agaagctgta
    33601 gctcgtgcta tccgtcgtaa ccgtgctggt tttgatgaag gaaatcgccc aatcggcagc
    33661 ttcctctttg tagggtctac tggggttggt aagacggagc ttgctaagca attggcactc
    33721 gatatgtttg gaacccagga tgcgattatc cgtttggata tgtctgaata cagtgaccgc
    33781 acagctgttt ctaagctaat tggtacaaca gcaggctatg tgggttatga tgacaatagc
    33841 aataccttaa cagaacgtgt tcgtcgcaat ccatactcta tcattctctt ggatgaaatt
    33901 gaaaaggctg atcctcaagt tattaccctt ctcctccaag ttctagatga tggtcgtttg
    33961 acagatggtc aaggaaatac agtaaacttc aagaacactg tcattattgc gacctcaaat
    34021 gctggatttg gctatgaagc caacttgaca gaagatgcgg ataaaccaga attgatggac
    34081 cgtttgaaac ccttcttccg tccagaattc ctcaaccgct ttaatgcagt catcgagttc
    34141 tcacaattga ctaaggaaga cctttctaag attgtagatt tgatgttggc tgaagttaac
    34201 caaaccttgg ctaagaaaga cattgacttg gtagtcagtc aagcggctaa agattatatc
    34261 acagaagaag gttacgacga agtcatgggg gttcgtcctc tccgtcgcgt ggttgaacaa
    34321 gaaattcgtg ataaggtgac agacttccac ttggatcatt tagatgctaa acatctggaa
    34381 gcagatatga aagatggcgt tttggttatt cgtgagaaag cctaagacag aattttgagg
    34441 ataaaaaaga aggagccagc tgaaaaaact ggttcctttt gaggtacgac gggcatgtcg
    34501 tatagtagaa gtgtactatt ctagtttcaa tccactatag tagctcagaa gtcggtactt
    34561 aaacgtgcta tatcaaaacc agtccttgaa aaacgtggat tggtttcgtg tttggattat
    34621 taccttgaac gacatgcgtt aaaagttagt tgaaccgccg tatgccgaac agcacgtacg
    34681 gtggtgtgag aggggctaga gattatcccc tactcgattt taaatcacat gacgttcaaa
    34741 ggcatcatct gaaatccctt gttccaagat gagttttgcc cattctttag cagagaagag
    34801 gctgtggtcc ttgtagtttc cgcaagattc gatggttgtc cctgggacat cttcccaagt
    34861 agtagtttca gcgatttcct tgagcgaatc cttgataaca gctgcgattt tagcactggt
    34921 gtgacgtccc cacataatca tgtggaagcc cgtgcggcaa ccaaatggtg aacagtcaat
    34981 catgccgtca atgcggatac ggataagttt ggctaagagg tgctcgatag tgtgaaggcc
    35041 ggcagtaggg atagagtctt cgtttggctg caccaagcga atatcataat tggagatgat
    35101 gtctcctttt ggtcctgttt cttccccaat caagcgaaca tagggtgctt tgacaatggt
    35161 gtggtcaagt tcaaaacttt cgacaataac ttcttttgac atggtaaatc ctttcagttt
    35221 tcttctctca ttatatcata aaggttgctc ctgagacaga gagaaaacct ctccgaggct
    35281 ggagaggttg aaatctttac ttacgatata agcggtcgta ttggtagtat gggtcaaagg
    35341 ttacgttgat acccagttta cgaaggacat tcttgtcttc atcagtcaag atgatggttg
    35401 agtgggcttc gcttcctttg aggttgccga gttcttccat agcgcgggca gcatcaggat
    35461 tttctgtagc tgtgatagca agtgcaatca ggatttcatt tgaatgaagg cgtggattgc
    35521 ggctaccgag atgatcgatt ttaagacctt ggattggctt aacaacttcc ggctcgatta
    35581 attttacttc tttagcgatg tcagctgatt ttttgatggc gttgatcaag gcagcggctg
    35641 tagggccaaa gagttctgag ttcttaccag tgacgatttc cccatttggc aattcaaagg
    35701 ctagggctgg tccaccagtt tcttctgctt tttggcgcgc aacgacagca accttacggt
    35761 ctgcaggtgt gataccgagg tcgttcatga gcaactcaat tttcttgacg gcagcttcgc
    35821 caactttttc agctttgaag tcaagaactg tttgatagta acgacggatg atttcttgtt
    35881 tagaagcttc gacagcagcc tcgtcatctg taatagcgaa accaaccatg ttgacaccca
    35941 tatctgtcgg tgaagcgtat ggtgattttc cgagaatacg ttccaacatg cgcttgagca
    36001 ctgggaagat ttcgatatca cggttgtagt tgacagtggt ttctccatag gtttgaagat
    36061 ggaaggggtc aatcatgttg acatcatcaa ggtcagctgt ggcagcttca taagccaagt
    36121 taactggatg atgaagggga agattccaaa cagggaaggt ttcaaattta gcgtagccag
    36181 acttgatgcc attgatttgg tcgtggtaca tattggacat acacgttgcc aattttccag
    36241 aaccgggtcc aggagcggtt acgacaatca agttgcgact ggttttgatg tagtcgtttt
    36301 tgcccatgcc ttctggggaa atgatgtgat ccatatccgt cggatatcct ttgattggat
    36361 aatgaagata agaatcaatt ccgtttttct caagttggtt gcggaaggca tctgcagcgg
    36421 gttggccagc gtattgtgta atgacaacgg aaccaacaaa aatccctaat tcattgaatt
    36481 tgtcaatcaa acgaagaact tcttggtcat aagaaatgcc taagtcgcca cgtgctttgg
    36541 aatgttcaat gttgctagca ttaatggcaa tcacaacctc aacctgctct ttcaattctt
    36601 gcaagagctt gattttgttg tcaggttcat aaccaggaag gacacgagca gcgtggaaat
    36661 cttctaacat tttacctcca aactctaagt agagcttgcc gtcaaattgg ttaatgcgct
    36721 ccaaaatatg gtcgcgttgt aaattcaaat attgttcaga actaaaagct tgttttttca
    36781 tttttttacc tctggactct attataataa aaaattggaa gttaggaaac tacggagcta
    36841 aaaaagaaat taaaaagatc aagcaaacgc ttgcacaaaa ttttaaaaag tgctatcata
    36901 gactatagat tatgaaaata atgaggtaaa cagatgcaag aaaaatggtg gcataatgcc
    36961 gtagtctatc aagtctatcc aaagagtttt atggatagta atggagatgg aattggcgat
    37021 ttgccaggaa ttaccagtaa gttggactat ctagccaagc taggaatcac agcaatttgg
    37081 ctttctcccg tttatgacag ccctatggat gataatggct acgatattgc tgattatcaa
    37141 gcgattgcaa cgatttttgg aaccatggag gatatggatc aactgattgc agaagctaag
    37201 aagcgtgata tccgtatcat catggacttg gtggtcaatc atacctcgga tgagcatgcc
    37261 tggtttgtag aggcctgtga aaatcctaat agccctgagc gagactacta tatctggcgc
    37321 gatgaaccca atgacctaga ttctatcttt agtgggtctg cttggaaata cgatgaaaag
    37381 tcaggtcaat actatctcca ctttttcagc aagaagcagc cggatctcaa ctgggaaaat
    37441 gaaaaacttc gccagaaaat ttatgagatg atgaacttct ggattgataa aggtattggt
    37501 ggtttccgta tggatgttat tgacatgatt ggcaaaattc ctgacgagaa ggtagtcaat
    37561 aatggtccta tgctccatcc ctatctcaag gaaatgaatc aggcgacctt tggagataag
    37621 gatctcttga cagtagggga gacttgggga gcaacgccag agattgccaa gctctactct
    37681 gatccaaagg ggcaagaatt gtctatggtc ttccagtttg aacatatcgg tcttcagtat
    37741 caggaaggtc agcctaaatg gcactatcaa aaagagctga atatcgctaa gttaaaagaa
    37801 atcttcaaca aatggcagac agagttagga gttgaggacg gctggaattc cctcttctgg
    37861 aacaaccatg acctccctcg tattgtctca atctggggaa atgaccaaga ataccgcgaa
    37921 aaatctgcca aagcctttgc aatcttgctt catcttatga gaggaactcc ttatatctac
    37981 caaggtgagg agattgggat gaccaactat ccgtttgaaa cactggatca agtagaagat
    38041 attgaatctc tcaactatgc gcatgaggct cttgaaaaag gtattccgat tgaagaaatc
    38101 atggacagta tccgtgttat tggacgtgac aatgctcgta cccctatgca atgggacgag
    38161 agcaaaaacg ctggtttctc aacaggtcaa ccttggttgg cggttaatcc aaattacgag
    38221 atgatcaatg tccaagaagc gctggcaaat ccagattcta ttttctatac ctatcagaaa
    38281 ctggtccaaa ttcgcaagga gaatagctgg ctaattcgag ctgactttga attgcttgat
    38341 acggctgata aggtctttgc ttatatacgt aaggatggcg accgtcgctt cctagttgtg
    38401 gctaacttgt ccaatgaaga gcaagacttg acagtagaag gaaaagtcaa atctgtcttg
    38461 attgaaaaca ctgcggctaa agaagtactt gaaaaacagg tcttggctcc atgggatgct
    38521 ttctgtgtgg aattactata aatatttttt gcagaaaaat ttaaaattga aatcgtataa
    38581 aaacaaggga agactgtata aaaggcagaa atcctttgtt ttttataacc aaggtttata
    38641 aaccttcatt ctcgaaattc aattaacttt acaaattccc actattaagg agaaagaaga
    38701 cgaacataaa gaagcgtatc cttagtgcag gcctgacttt tacatctgat ttgcttttag
    38761 ctgcttgcgg ccaatcaggt tcagatacaa aaacttactc atcaaccttt agtggaaatc
    38821 caactacatt taactatcta ttagactatt acgctgataa tatagtcaat tgaaacaaga
    38881 acaggacaaa agagcctcat aaaaggtatt gcaacttggt aatacctttt tgaggtgctt
    38941 tttgatatga gcccatgttt tctcaatagg attgtactca ggtgagtagg gaggaagagg
    39001 taaaagttta tacccaaact cttcacacaa gagttctagc ttccccattc tatggaatct
    39061 tgcattatcc ataataataa ccgatggtgt ggttaatgtt ggtaagagaa atttctgaaa
    39121 ccaagcttca aaaaagtcgc tcgtcatcgt ctcttcgtaa gtcattggag cgattaactc
    39181 accattcatt tgttagacct gcaaccaaag aaatcctctg atatcttctt ccagatactt
    39241 tgcctcttat taactgatct tttaatgagc gaccatattc tcgataaaaa taagtatcga
    39301 atcctgtttc gtcaatctaa acaggtgcta ggtgctttaa actattaaaa ttcttaagaa
    39361 ataaggctac tttttctggg tcttgttcat agtaggtgtg gttctttttt tcgagtgtag
    39421 cccatagctt tgagcgcata gtggatggta gttggatgac agccaaagtc agaagctatt
    39481 tcagtcaaat aagcgtctgg attgtcagta agatagtttt taagtctatc tctatcaact
    39541 tttcttggtt ttgttccttt tacttggtgg tttagctctc ctgttttctc ttttagcttt
    39601 aaccagccat aaatggtatt acgtgagatt tggaaaacgt gtgatgct
//
LOCUS       DBEJJE010000016        39316 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEJJE010000016 DBEJJE010000000
VERSION     DBEJJE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.16"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(99..1463)
                     /locus_tag="ACL3F5_000829"
     CDS             complement(99..1463)
                     /locus_tag="ACL3F5_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514663.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRVAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(1451..2146)
                     /locus_tag="ACL3F5_000830"
     CDS             complement(1451..2146)
                     /locus_tag="ACL3F5_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0514664.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAEIKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            complement(2146..2730)
                     /locus_tag="ACL3F5_000831"
     CDS             complement(2146..2730)
                     /locus_tag="ACL3F5_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0514665.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            complement(2741..4462)
                     /locus_tag="ACL3F5_000832"
     CDS             complement(2741..4462)
                     /locus_tag="ACL3F5_000832"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514666.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDEGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENTDKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            complement(4446..6200)
                     /locus_tag="ACL3F5_000833"
     CDS             complement(4446..6200)
                     /locus_tag="ACL3F5_000833"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514667.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAINDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6360..7352
                     /locus_tag="ACL3F5_000834"
     CDS             6360..7352
                     /locus_tag="ACL3F5_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0514668.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            complement(7972..9534)
                     /gene="guaA"
                     /locus_tag="ACL3F5_000835"
     CDS             complement(7972..9534)
                     /gene="guaA"
                     /locus_tag="ACL3F5_000835"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0514669.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAVEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            9676..10374
                     /locus_tag="ACL3F5_000836"
     CDS             9676..10374
                     /locus_tag="ACL3F5_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0514670.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(10417..11313)
                     /locus_tag="ACL3F5_000837"
     CDS             complement(10417..11313)
                     /locus_tag="ACL3F5_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0514671.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGTLMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLIIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYTIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(11322..12257)
                     /locus_tag="ACL3F5_000838"
     CDS             complement(11322..12257)
                     /locus_tag="ACL3F5_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0514672.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(12254..12979)
                     /locus_tag="ACL3F5_000839"
     CDS             complement(12254..12979)
                     /locus_tag="ACL3F5_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0514673.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQIDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(13063..13698)
                     /locus_tag="ACL3F5_000840"
     CDS             complement(13063..13698)
                     /locus_tag="ACL3F5_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0514674.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKFLKDYLY"
     gene            complement(13700..14527)
                     /locus_tag="ACL3F5_000841"
     CDS             complement(13700..14527)
                     /locus_tag="ACL3F5_000841"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0514675.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(14549..14884)
                     /locus_tag="ACL3F5_000842"
                     /pseudo
     CDS             complement(14549..14884)
                     /locus_tag="ACL3F5_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(14885..15601)
                     /locus_tag="ACL3F5_000843"
     CDS             complement(14885..15601)
                     /locus_tag="ACL3F5_000843"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0514676.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIRVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            complement(15681..15872)
                     /locus_tag="ACL3F5_000844"
     CDS             complement(15681..15872)
                     /locus_tag="ACL3F5_000844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514677.1"
                     /translation="MKIQRRQNRNQGGLAFRFMKGLVNFLGVIASGAIRDLWRYSCSQ
                     LVYQWAWSCCLKASKESLD"
     gene            16124..16735
                     /gene="def"
                     /locus_tag="ACL3F5_000845"
     CDS             16124..16735
                     /gene="def"
                     /locus_tag="ACL3F5_000845"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0514678.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            16780..17508
                     /gene="rlmB"
                     /locus_tag="ACL3F5_000846"
     CDS             16780..17508
                     /gene="rlmB"
                     /locus_tag="ACL3F5_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0514679.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(17547..18458)
                     /gene="trxB"
                     /locus_tag="ACL3F5_000847"
     CDS             complement(17547..18458)
                     /gene="trxB"
                     /locus_tag="ACL3F5_000847"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0514680.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(18524..18748)
                     /locus_tag="ACL3F5_000848"
     CDS             complement(18524..18748)
                     /locus_tag="ACL3F5_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0514681.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(18826..19569)
                     /locus_tag="ACL3F5_000849"
     CDS             complement(18826..19569)
                     /locus_tag="ACL3F5_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0514682.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(19569..20369)
                     /locus_tag="ACL3F5_000850"
     CDS             complement(19569..20369)
                     /locus_tag="ACL3F5_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0514683.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(20527..20883)
                     /locus_tag="ACL3F5_000851"
     CDS             complement(20527..20883)
                     /locus_tag="ACL3F5_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0514684.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(20877..21407)
                     /locus_tag="ACL3F5_000852"
     CDS             complement(20877..21407)
                     /locus_tag="ACL3F5_000852"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0514685.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(21407..21901)
                     /locus_tag="ACL3F5_000853"
     CDS             complement(21407..21901)
                     /locus_tag="ACL3F5_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0514686.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            22036..22482
                     /locus_tag="ACL3F5_000854"
     CDS             22036..22482
                     /locus_tag="ACL3F5_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0514687.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            22479..23126
                     /locus_tag="ACL3F5_000855"
     CDS             22479..23126
                     /locus_tag="ACL3F5_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0514688.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWILMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(23147..23728)
                     /gene="pdxT"
                     /locus_tag="ACL3F5_000856"
     CDS             complement(23147..23728)
                     /gene="pdxT"
                     /locus_tag="ACL3F5_000856"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0514689.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(23729..24604)
                     /gene="pdxS"
                     /locus_tag="ACL3F5_000857"
     CDS             complement(23729..24604)
                     /gene="pdxS"
                     /locus_tag="ACL3F5_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0514690.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(24756..26135)
                     /gene="nox"
                     /locus_tag="ACL3F5_000858"
     CDS             complement(24756..26135)
                     /gene="nox"
                     /locus_tag="ACL3F5_000858"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0514691.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFGRLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            26429..27352
                     /locus_tag="ACL3F5_000859"
     CDS             26429..27352
                     /locus_tag="ACL3F5_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0514692.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            27412..28017
                     /locus_tag="ACL3F5_000860"
     CDS             27412..28017
                     /locus_tag="ACL3F5_000860"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0514693.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEEFDWENL"
     gene            28035..29282
                     /locus_tag="ACL3F5_000861"
     CDS             28035..29282
                     /locus_tag="ACL3F5_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0514694.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAGGHGHGDADATS
                     GASDAGDAGGHGGGADATAGASY"
     gene            complement(29399..29656)
                     /locus_tag="ACL3F5_000862"
     CDS             complement(29399..29656)
                     /locus_tag="ACL3F5_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0514695.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(29698..31734)
                     /gene="glyS"
                     /locus_tag="ACL3F5_000863"
     CDS             complement(29698..31734)
                     /gene="glyS"
                     /locus_tag="ACL3F5_000863"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0514696.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(31946..32863)
                     /gene="glyQ"
                     /locus_tag="ACL3F5_000864"
     CDS             complement(31946..32863)
                     /gene="glyQ"
                     /locus_tag="ACL3F5_000864"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0514697.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(32882..33643)
                     /locus_tag="ACL3F5_000865"
     CDS             complement(32882..33643)
                     /locus_tag="ACL3F5_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0514698.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(33916..34758)
                     /locus_tag="ACL3F5_000866"
     CDS             complement(33916..34758)
                     /locus_tag="ACL3F5_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0514699.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(34872..36263)
                     /gene="pgdA"
                     /locus_tag="ACL3F5_000867"
     CDS             complement(34872..36263)
                     /gene="pgdA"
                     /locus_tag="ACL3F5_000867"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0514700.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(36501..36869)
                     /locus_tag="ACL3F5_000868"
                     /pseudo
     CDS             complement(36501..36869)
                     /locus_tag="ACL3F5_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            37108..38085
                     /locus_tag="ACL3F5_000869"
     CDS             37108..38085
                     /locus_tag="ACL3F5_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0514701.1"
                     /translation="MLKLGIIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            38082..39164
                     /locus_tag="ACL3F5_000870"
     CDS             38082..39164
                     /locus_tag="ACL3F5_000870"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0514702.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLTSDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT        11912 a         8454 c         6708 g        12242 t
ORIGIN      
        1 cctgaagtta attttctaat aaatatcaat atgtgttagt atcttttaaa tttttagaca
       61 atttaccagt tctatagaca tgtttaacag actctatttt acaattcaaa aatttcatct
      121 gccacttcat ttaaaaattc tatatcatgg gaaacaataa aaattatttt atccatggtt
      181 ttatacttat taatcagttc agatattttt atcatattgg aataatccat accacttgaa
      241 ggttcgtcaa aaaagacaaa tggagaattc ttgcacataa cagatgctat tgcaaccctt
      301 tgcttttgcc ctcctgataa actcatcgga tgcctttcaa taaattcgtc caggcctaaa
      361 tcttttaaaa tgattttcgc cttttcttca tcaaaattct ttactcctaa tctaagctcg
      421 ttgaatactt catctgtgaa taattgatga tttacatctt gcataacaag tgaagagttt
      481 ttgagtcttt cttttttaga tagcttctct cccttaaaat aaatttcttc ttttgatttt
      541 ttctcaagac ctattaaaca tcttaaaagc gttgattttc ctcgtccgtt ggatcctatt
      601 atgccataaa ttttcccaag cttgaacgaa atatctttta agcttaaaca ctcatcatca
      661 gtaaatttgt agctaagatt ttttatctga tactctccac cttcttttaa ataaggaact
      721 tttaatttac ttaattcttt atctcttaaa cttaaagcat ttaattcatt tttatctagc
      781 tttaaaaatt cacttctagt ataagttttt ttaagctttc ctttatctat taaaaataca
      841 cggtcaacta tgtccatcaa ataataaatt ctatgctctg caacaattat gcttatgcct
      901 ttctctttta atatctttag catctttgcc aaaacactta tgcttttaat atctaaattc
      961 gatgaaggct catccataac tataatcttt gtacctgcta tataagaagc tgcaatgcaa
     1021 agaatttgtt tttcaccgcc ggatagatta aatatatttc tgttcaaaag attttttatc
     1081 gggaatatct caagcatatc cttcaaacgc ctgtccatct cttctcttgc aagaccgata
     1141 ttttccaaat aaaataataa ttctaatgtc gtattgacat taaaaaaata tgtcttagga
     1201 ttttgaaaaa cagttgaaac aagcattgag atttgataaa gttccaaatt ttttatattc
     1261 ttaccatcaa taattatttc gccctttgtc tttgcgttat cataccttac agctagtcca
     1321 ttgattgaat ttattaaaga tgacttacca tttccacttt ttcctgtaaa tagcacgcac
     1381 tctccctcgg ctatggatag tgatatatca tctaatatat gctcttcacc ataatcaaga
     1441 cttaaatttt ttatttcaac catattaagc ctcccacaat aagtccaaca accgctaaaa
     1501 cataaacaaa atcaattagc tgtatcttta cgcgaatgta tctggtcttg gcaattggat
     1561 tttctattgc ctttatttct gccgcttttg caatgtcatc tgatatatta gatgatataa
     1621 tgagtagtgg cacagaaaca tattcaagat atttgactgg gtttttaaaa tttatccctc
     1681 ttactctcat agccattttg atgtttttct tctcctcctt aaaagatggg aagaatctaa
     1741 acataaccgc aataggtatg gatacattct ttgaaatctt aagcttatcc atcgatgaaa
     1801 ttattgcgcc tacatccgag gtctttatca taaagcttgc tgccataaat ggtaaaataa
     1861 acattctaat aacaataggt atactcaaaa acatcttaac tatagggttt aattcagata
     1921 acaccataaa attaggcaag gagtaaagta tcccacacaa tataatccat ttgaaaagtg
     1981 tttttttgta tccattcaaa taaagcaaaa taccaataag acaaacaatt gccagctcaa
     2041 aacggatgtt tatgctatgc ataacagtta agcctgtgat aaatacgact aatatcttag
     2101 agatcggatt gggattaaag ggagcatttg aagaaaaagt aggcattata caatgcctgc
     2161 tttttcaaag tgttttttca atagagcctt gcctatatat gctccaagaa ttcctcctaa
     2221 gaaagcacct aaggctacta aagccatgtg aggataagtt attaactttt ctaatacatc
     2281 aacataatct tttcccatcg tcatcaaaga ccactccata tatttttctt ttgctaaaag
     2341 catttgcatt aaagagctac atatccatgt gctgaagatt gcataagaaa gcatattgta
     2401 tttaaatgaa ttataattac caatctttct aattaattct gctattatca ttactataag
     2461 tgataaaacc acaactacgt aggtatgacc agctgcaaac atcacaagtg gtgatatcat
     2521 accaaatata aatagtgccc atggcttttg aaccttagcc ataaataaca taacaacagt
     2581 tcctgcaact atggctaata ctgtcgggta tattaagaac aatattggaa tcaagcccat
     2641 cataccaact ccaaacatga aggcaaaata aattacgcca aaaacaccga tgcttactaa
     2701 atcttttact tttaattttt tattatccat tgtagtcctc ctaataaata aattcttctg
     2761 ccatttttgt cttttctatt aaatttttgt aaatttttga tttttgtaaa agctcttcat
     2821 gcttaccttc gctttctact cttccgtttt gaagaactac tatcttgtct gtattttcta
     2881 tggatttcat tctatgtgaa atgattacaa cagttttatc tttaactaaa ttatttaaag
     2941 actcttgaat ctttttctcg ttgttaacat caaggcttgc tgttatctca tctaagatca
     3001 atatcggcgc atcttttaag aaggctctgg ctattgataa tctttgtctt tctcctcctg
     3061 atagctcagc tccgttctca ccaataactg tatcgaaacc tttatccatt ttttctataa
     3121 aatctgtgca atttgcaagt tttgctgctc ttttaacctc ttcgtcactt gcatcttgct
     3181 ttccgattct aatattttcc ataacgcttt gattaaagag aaccacatct tggaaaacta
     3241 tagagacctt atcaaaaaga gattctgttg atatttcttt tatatctttg ccatcgatta
     3301 agatttgtcc ctcgtcataa tcataaagtc ttgatataag tttcaagata gttgttttac
     3361 cgcagccact tgcacctacc aaagcagtga cctctccctg cttagcttta aaacttacac
     3421 catttaaaac ttttgcgtct ttattgtagg caaactcaac atcttttaga tcaatatcaa
     3481 atttttttaa gctatagtca tcgccttctt gtagatcttg attttgaatt tcttttaatc
     3541 tttctatttt gggcgataaa taaaatattt ccatcaagcc ctctttagat gcatctaaag
     3601 agtcttttat cttcatagca gctagtaaat atcctataag gtagagagaa tttatctctt
     3661 tattaataat tagatttacg ccgacaaata tcacaacagc aagagatata aagctaaata
     3721 ttgaagatat agacaaagtt aaaattgtag ttacttccgc ctttaagtgt actctctcac
     3781 tatcttccat ttttttatat aagtcatctt taatatcctt cgataaatta tatgctttaa
     3841 tctccatttg catttcgata ttttcttgaa agctttctga gttttttctt aagacatcat
     3901 aatatctatt ctgtccatta acctgatatt ttttagataa aggtataaat ataaagctta
     3961 aaatagatgg aataattaca gctaaaccca tcttgacatt gcccgctagc atcattacag
     4021 atattaatgg gaaaaacagt accatgccgc ccacctttgg tattgagtgg ctcattgcat
     4081 gctctatgcc ttcaatatca gccatgattg tttgtgaaat gtcggaaatg tcatgtttag
     4141 aaaagtaaga tagaggtaat tttgataaat tctccgctgt ccttattctt aaatctgcac
     4201 tttcttgata ggttgtgtta tataatttat cgtattcgat agaaagcaaa atatacattg
     4261 ctatcaaagt caaaactgag aatactatat aaaagccatt gcttttgccc atattttcca
     4321 aaacttcctg agcaaaaatc ataagtaata tggcaggaag catgtttata caataaacga
     4381 aaaatgaagc cagtgttgct ttacttaaat ttcttgctcc tccatctgta agagcaaatc
     4441 tttttttata aaactctttc atttgaaacc ctccattcat tcgcactgtt aaacatctct
     4501 tgcaggctct tataccttgt atcttttgac attaattctt tgtcagaccc tctttctata
     4561 atttttccac tatccataac aataatttca tcaaggtctt taattgtaga tagcctgtgt
     4621 gcaatcatga taactgtttt atccttcata agatttttga aagctttttg caattcaaac
     4681 tcgttatctg ggtcaataga tgctgatgct tcatccataa taataatttt ggaatccttt
     4741 aaaattgctc tagcaattgc aattctttgt ttttctccac cggataaata aacacctttt
     4801 gagcctatga ttgtattttc tctttctggg aatttgtcta atattaaatc gcatcctgct
     4861 aattttaagg ctctcataac gtcatctttc gtcgcatctt tattagctaa agctacatta
     4921 tcataaatgc tcttcttgaa taattttgaa tcttgaaaaa caaaggaaat ggctttaatt
     4981 aaggcttcgt cagaatattc acttattgct atcccgccta tctttatgct tcctttatta
     5041 acattgtaaa aacctgatat aagttttgct actgttgatt tgcctgatcc agatgaaccg
     5101 acaagtgcgt aggactttcc ttcttctaaa ttaaaggata aattttcaat gacagcttta
     5161 tcattataag caaagctaac attctcaaat tctatattat agtttttaaa attattgaca
     5221 ttaccatgca ctaatttgtc tttttgcata tcttcgtaaa gcgcctctaa agtatctact
     5281 gcataatttc cttgagaaat atacatggag taccacatca ttctcatgaa tgaaacaaag
     5341 agaactcctg ataaaaataa aatcatgata agctcaagta aaatcacctt tgcgctagct
     5401 aagctagtca taaaataaac tataggaata attaaaattg caatcagtcc aaaaaataac
     5461 cattgataca aaacataagg ccttttacaa gatagggaat aatcataagc atactttgag
     5521 taatcgttta tcgccttata aaagctttta aaagactcta catttgcttt aaatattttt
     5581 acaacttgca ttcctctaac gtactcgaca gtctcagcac ttagtttaga tagggattct
     5641 tggtatatct tcataaattc ttgctcgccc atcattgccc ctaaaattaa gccaccaatt
     5701 atagtaagag caagcaaaat tatgccaact cttatactta ctataaagcc aagtgcaagt
     5761 acaagtacgg gtgtgattat tgcctgagaa ctatcgggaa tcatgtgtgc taccacctga
     5821 tgagtttgtg ctgcattatc atctatgatc tttcttattt gaccagatgg atttaagtca
     5881 aagaacctaa aacttgcttt ttccagacca tcgattcccc tttttcttaa atttgtttca
     5941 agcctaaatc ccaagatatg tgaaaacatt cctgagacaa aataaaatat cgctccactt
     6001 gttagtgtaa taacagattt taatgctata ctctctgcac cggataagtt tgaattaatt
     6061 attaacttat ctagaaattt gtagattaaa taatatccat atactgtaag tagagcagat
     6121 atagcagaaa aaattatggc caaaacccca agatatttct tatcttggac ataagcaaat
     6181 agttttttgt aaatcttcat aagcatatct cctttcttta atatcccttt tagatataaa
     6241 ttcgcttaat tgataatatc tatcattgct tttctattat acatctgtta taattactaa
     6301 tacaatagtt ttgaattaat aaggctaatt ggaatattgt ctaaaaggga tagtgtgtta
     6361 tgtcatatta tgattttgta aaagattata tgaaagtaga tgaatgtaaa aacaatgaga
     6421 agtattcaag tgcaggtcat acattttgtt ggaaaaaaga gaattcaact tatgcagaag
     6481 gcctatattg gttttatgaa ggaggcagct tcattatcga tatacatgat ttttatatca
     6541 aagaggaagt agttcaaaat agcacttata gtatgtcaga ctatgtttca atttattcaa
     6601 gttacattgt cagtgcaaac ggagaaaagt ttaatccgta tcaaactatt accgcaaact
     6661 ctttatgtac ttttgatttt gataatataa aagatgattt tgttttttta ttacacgaga
     6721 attgttgtta tcttgctgtt tccattggtt ttaaaaaaga gctaatagaa aaacatttag
     6781 catctattaa cattaatcca gaatcttttt attcaacctt gcttcaaccg aatcaaataa
     6841 tacttacaaa ggccttagaa agagtggcaa tggaaatatt aaattgtaag atggacgctc
     6901 ctgccgctga ttttttcttt aaagcaaagg caaatgaatg gataagtata gtaattgaca
     6961 catacttaaa tagaaaaaaa tataaaattg aaattgatga tgataaagca cttgaagatg
     7021 tagcaagatt cttagatgat cattttgcaa cgaatgtaaa tcaaggcacg cttgaaaaaa
     7081 tatctaaaat gagtggtact aaattaaaaa atttatttaa ggaaaaatat tgtcaaagca
     7141 ttacagagta cactcaaaga aaaagaatga atgtagctga aactcttctt ttaaacactg
     7201 aactacctat aaaagagata gcagaatctg ttggatattc atctgccagc aaattttcta
     7261 tctattataa aagatacaag ggaaaacttc caagtgaagt ccgtaattta gcttgcaaac
     7321 atcacaattt taaatgcgat tattgtgatt aaagtaattt tttacaagcc atgtttttat
     7381 atgaatttaa gtgtatatgt gcatatatag tctgaataaa tttgatttga aaaatggata
     7441 aaaaaataaa ggcagtccga agaccgccaa tatttatctc tctgcacctt tgctatggtc
     7501 tttcttattt gacttagatt tgtcatctgt cttaaagctt tttatttgcc ctaatatgga
     7561 ctttttatcc ttgtcttgac tctttacttg ttcttttgct tttaagagct tagaagacaa
     7621 aaagagatat tatattaaaa caatatttct ccggtactgg gactgggacg ggactaaaaa
     7681 tctgaaaacg tcctataatt aggtggattt agtgatatta taaaaaatag aatctagtat
     7741 tttgaatggt tttggatata ttgtacgttt ggaaaagaag aatgggagta attttaaact
     7801 aacaaaaaat gctttgaaat cagtgtttca gagcattttt tgtccaaatg taaatcactt
     7861 ggaactatta ttcaatttat tctttttagt aaatgttccc gttttaatcc cagttacagt
     7921 ttttaatcct ctgtaaccgt tgattttaca aagcttttaa tttttttgcg attactccca
     7981 ctcaactgtt gcaggtggtt tacttgtaat atcgtagacg atacggttaa catgatccac
     8041 ttcatttacg atacgtactg agattttttg aagtacttcc catggaattt tggcaaaatc
     8101 agcagtcata ccatcgatag aagtgatagc acggattgca atcgtgtagt catacgtacg
     8161 accgtcaccc ataacaccga ctgaacgaac gcctgtgtta acagtgaagt attgccaaat
     8221 atcgcggtca agtccagctt tagcgatttc ttcacgaaga atagcgtctg attcacgaac
     8281 ggtttcaagt ttctcttcag tgatttcacc catgacacgg atagcaagtc ctggtcctgg
     8341 gaatggttgg cgccatacga tatggtctgg cataccaagc tctgtaccaa gagcacgaac
     8401 ttcatccttg taaagagtat tgagtggttc aatcaattca aactgcatat cttctggaag
     8461 accacccacg ttgtggtgtg acttgatagt ttgagctgta tccgtaccag actcgataac
     8521 atctgtatat aaagtacctt gagcaaggaa tttcacatct ttgagcttgc ttgcttcgtc
     8581 atcgaataca tagacaaact cgttaccgat gattttacgt ttttgttcag ggtcagaaac
     8641 gccagcaagt ttgtcaagga aacgtttagc agcgtctgct ttgacaatat tcaaaccaaa
     8701 cttaccaccg agcatgtcca taacttgatc agcttcgcct ttacgaagaa gaccgtggtc
     8761 tacgaagata cagatcaatt gatcgccaat cgctttttgg agaagaaccc caacgacaga
     8821 tgagtcaaca ccacctgata gaccaagaag gacacgttta tcaccgacgg tttcacgaat
     8881 ttttttgatc tgcatgtcaa tgaaattatc cattgaccag tcacctttag ccttacaaat
     8941 gttaagggca aagttacgaa ggatatcatt tccgtataca gaatgacgaa cttctgggtg
     9001 gaattggata ccgtaaatgt gtttatctgg gttttcgatg gctgcgtatg ggcagtcagc
     9061 tgatgtacct gtacgaacaa agtcagcagg aatctcagta accgcatcac catggctcat
     9121 caaaacagtc tgttcatcag gtgttgattc aaaaagcgct gatggtgtgt gagttagggt
     9181 tgattgaccg tattcacgat ttccagcatc acctgcagga acaacttttc ctccaagttt
     9241 atgggtcaat aactgcatac cataacagat tcccaaaatt ggaattccga gttcgaagat
     9301 ttctgggtca atatcaaatg aaccatcttc atatacagaa tttggaccac ctgatagaat
     9361 aattcctaca ggattgactt cacgaacttc aacagctgaa attttatggc tttttagttc
     9421 tgaaaaaaca ccaatctcac ggatacggcg tgaaatcagc tggttgtact ggctaccata
     9481 gtccaatacg atgatttttt ctacatcttg caaatcagtt gaaatgttgc tcatcttttt
     9541 cctttctcaa aagaaatatc ttttctcaat attctatcac aaataagggc gaattaccaa
     9601 ctaaacaagg cgaagtttga ctttttctag tttattgggg tacaatagag aaaagataga
     9661 aatgaagtga aaaatatgct acctgcttat atgaaaatcc atgatcagat aaaaaaggat
     9721 attgacgagc accgttgggc tattggtgag aggcttccca gtgaaagaga tttagctgag
     9781 cagtttgcgg tcagtcgcat gaccctccgc caagctgtat ctctattagt cgaagaaggc
     9841 gtcttagagc gccgtgtagg aagcggcact tttgtttcca gtactcgagt acaagaaaag
     9901 atgcgaggga caaccagttt tactgaaatt gtcaaatccc aaggtaaagt tccctctagc
     9961 cagctcattt cctacaaaaa aaccattccc aatgagcaag aagttgccaa gctaggaatt
    10021 tttccaacgg acaatattat ccgaatggag cgggtccgct atgccgacca agttccccta
    10081 gtttatgaag ttgcttctat tcctgaaaaa ttcattaagg actttaaaaa agaagaaatc
    10141 accagtcatt tcttccaaac cttgcaaaaa catggctatc gtatcggcaa atctcaacag
    10201 accatctatg ctcgccttgc taaagaaaag attgcccact atttggaagt tgaaaaagga
    10261 catgctattc ttggattgac ccaggtttcc tacctagaag atggtactgc ttttgaatac
    10321 gtaaaaagtc aatatgtagg cgaacgcttt gaattttatc ttgaaaataa ttagattacc
    10381 acgcaaaaac tctctgtcac ggacaaagag tcttttttat ttttctaaga ataaatcttt
    10441 caaagaaatc aaagttacag caaacaatat cattgccata ccaagaaaat caatggtata
    10501 aaattgttca ttcattatta agaaggcaaa gaaaaccgcc gatattggct caattgaagc
    10561 caacaagctt gacttgaccg gtcctatcag actggctcct ttaaggaaag ctgtataggc
    10621 aaagacagtc ccgataagga taatgcctgc aaacgcaagg agaaaatcaa gactagtcgg
    10681 gatatcggcc tgtagaaccc ctgtaaaagg aagggcgacc aaacctgcta tgaccattcc
    10741 cacaccaatg atcaagctgc tcccccactt tttaatcaag gctatgggta aaatgatata
    10801 cagagcataa gtcaaggcag aaaagagacc ccagaacagg ccagcaggtg tcatggataa
    10861 ctggtccaac tgcccatgtg ttgcgatcag gaaggttcct ccgatggcga atatgatgga
    10921 aactatctct cccagtgtcg gtgccaccct atccttgata cagctataaa ttaaaattcc
    10981 gacaggacaa acatactgaa gcaccgtcgc tgttcccgca ttggtctcct gaatagcaga
    11041 cagataggcg aattggttga gaaaaagacc aatcagagca aaaataagaa gagacagcaa
    11101 actctttcta tcctttaaaa agaccagtat tttatccttt gcagtagcat aagccaagag
    11161 catgagagtt ccaccagcga ttaaaagacg caagttggtc aagaccagag ccgaaattcc
    11221 gtgtgccatc aggtattggc cactcgttcc tgacaacccc caagcaatac cagccacaac
    11281 tgttagtaaa gtccctttta aactatttga catgtctctc cttactcttc tttgcgaatc
    11341 aagttcatca cttgattgcg atctaatatc cattgagctc tctcgtcctt ttcataggta
    11401 cgattcgata ggaaaatagt ggcttcttgc ttctgacgat tccacatgat aaaggtacct
    11461 gtatagcccg tatggtctag ccaatctcct tccaaattcc atgctaaaga acgttccttg
    11521 tcatccaaag gagaaaaatt ttgatttaag tctcttgcaa aatcatctgc taaatagtgt
    11581 tctaaaaaga tttgtaaatc ctttatagtc gaaaataaac cagcactccc agcatgtcta
    11641 cccaggagac gagccttggg atcatgcact atgcctgcct ctacacctct aactgttgga
    11701 acagcaagct caactggccc aaacttagtt tccgtcattc cccaaggttt ccagacttga
    11761 tcctttaaaa tcacatccaa atcttgatta aaaattcttt ccaaaataaa gcccaacagc
    11821 aaaaaatgga catccgaata aagaaaggct ggctgacttc gtctgttgag atgaaacatc
    11881 gcttccttta attcaggggc tgttaaaaga tcacgattag gaataaaagg atcaaggtct
    11941 gttgcatgag tcaagagctg gcgaatagtg atgtctggat aatcactctc aggtaaaaaa
    12001 tctattacca gtctatcaat atctaattga cctatttccc acaagaaggt acaaactgtg
    12061 ccaaccccaa caaccttgct gacactagct aggtcataaa ctagtcctgc ctcagtctgc
    12121 aagccatgct ctgggtcact ctggcctaaa tagaactctg tccattgatt gtccttaaaa
    12181 tacgcaaaag aggctccggg ataaattcct gcctcgattt gttcttctat ttttttaata
    12241 atcttggtcc acttcatact tcttcaaacc acaattcaac attatttcta tctttaccaa
    12301 ggaagaattt ttcagactta ggaataaaat attcagtaga ctcaaacttc tggcgaagac
    12361 ttgctatgtc taattcattg accaagaact tgagcataga taagtcccag gtaaccgtat
    12421 tgtccacagt caaatcctgc ccctgagctg gaataaaatc aagggatgcc ccaatttcag
    12481 atgattccaa gaaactttcg atatcagttg ggagatgtaa ttccatagaa atctcaaatt
    12541 tacttaaaga aattgatgcc aaatctattt gaaattcagg cttttctcct acttctacta
    12601 gacttgctct gtcatcttcc gcatgaatca aaatcaaatc atcttctggt gagaaaattt
    12661 caaaagcgta gccattttga cctttatata atcgatgaat cgaatctgtt ttagataaga
    12721 ttccttcaat ttctaaggga ttttccacct tgacaatcaa tctagctagt ttttttcttc
    12781 cctctacctt acgagtacgc atactgggag cttcttctaa aaccagcttt tcaagacccg
    12841 tttggtcacc tagtgacaga aaggccgatt cttctaacaa ggccttcatt ccaagggttt
    12901 caatataaaa tgtttcattt aattttctat tattagcttt taaagtagga ataatccgta
    12961 caatctgatt tacattcata aattcctccg tcacttttta ttttaaagga ttttagaatt
    13021 ttttacaaga tattatgctc aaatttaaca ttatttagct atttagtaaa gatagtcttt
    13081 caagaatttt gacaaagcct gataaccagc aatactgagg tgcagtccat cagttgtata
    13141 ttcttttttg agttggcctg cttggtctgt caaacaatca aatactggca caaattccac
    13201 ctgcatatag gcagatgcaa gctcttgata ggcttgattc cagttctgaa ttttttcatt
    13261 cgagcggata tagactgcct gctggtactc ctctccctca ttgacaggca aaatggaaag
    13321 caatttaatc tctgtcaatg gataatcgcg agcaacggat tgaatgatag cttcgagatt
    13381 attgagagcc tcattcacag gaacatcctt tccgatatca tttgtcccaa tcagaagaaa
    13441 aattttatct actgctccac catatagatg agcatcaaga ttctctagta acagtcctgt
    13501 ctgatagcca cgaattcctc gattgacaat cgtctttgaa gtcccaaata gctcctgtag
    13561 aggataatac tcgacaatgg aatccccaat aaaaagaatg tttggttcta caacagaaat
    13621 gtgatttagg tgacgatact tagtttgaat tttttcttgt tcctttagga gccaattttc
    13681 taataactgt actgccactt cattctcctt tttctaacca gttttccaag acttgataaa
    13741 ctcctccttg gctgttggct ggtgctagag cagtcgccac agctttggct ttctcatcag
    13801 cattttccat cgcataggca attccagcca tttcaagcat ttcaacatca ttttcactat
    13861 caccaaaagc catgatttct tgggatttca agtcccagcg cttgagtaat tcctccaagc
    13921 cccatgcttt atgaatccca gcttggagga tatcaatgca accatagcca ctggatacag
    13981 ctcggacacg gccatcaaag agagcattga tttcttccaa aaccgaactc aaacgttcct
    14041 caccaacaac catgctcatc ttgagcacac caccaaagag gtcagatgtt aattcatcca
    14101 caaattgcat ccgttggtag aatttttcaa tcatttctgg agtcataaaa ctttcaagat
    14161 ctgtaaaaat cgtaccttcc ttgacaaaat cacccttcat ccccgttaca acaaactggt
    14221 cctgacacgc tcgaaccttg aaatgagtca aagccttgtt gacaatggcg tcatcccatg
    14281 tctgagcctg aatcaattca ttgttttcaa aaatacgagc gccattagca acaaccagaa
    14341 ccactcgatc caccaaggga ctcagtagtt gtctcatgcg gtgaatttca ttgcccgtcg
    14401 caatgacaaa acgaatgccc ctttgatcca actgatctaa aatcttttcc aatcgtggga
    14461 gatcaagctg acctctagca tccagcaagg tcccatccat atctgtcgca attaccttaa
    14521 tcatcattta ctttcctctg gattcaagct aataccactt caatcccaca tgttcattca
    14581 tttctttata ggctgtatca attcgttcct tagtcgcttc atctaactgg tcacaatgac
    14641 tgccatcctc tataaaatct tccaaaatat aagtttggta atgatacaag ggatatcctt
    14701 ctggtgaaaa ggttcccttt ggtgttcgat tgacctaagt aggatgagct ttagctgttc
    14761 cgatagttgt ttttccatcc ttcttcttga tggtgacatc catgagaaca ccacgttcag
    14821 tccacttagc attctcttca tctcccatag attcaatccg ttgattggaa atgaagttcc
    14881 ccatttaata gataatgagt ttcttatctc catctttttc aaccgtttca gatggttcaa
    14941 caacgtgagg atgccctcca aagataatat ccgctcccca atcgatcatc ttgtgataaa
    15001 gagctttttg ttcttcagtt ggttccaatc gatactcaac acccatctga ggcatgataa
    15061 tggtgatatc tgcttccttc tctgcccgtt caacttcagc ctttatctta tcttcgttta
    15121 aatctgaaag ataacgatta tagtcttcct gaaaaatata ctgctcaatt ccattgaaac
    15181 cataggaata ggctaacaat gcaaccttga tagcattcac ttccttaatg accagcggag
    15241 cctgatcacg tggttcgtgc gtataaactc tgattggagt gattccagct ttctcaataa
    15301 tatcggccat tgaaataact ccctcaattt gcgaatccaa aatatgatta tgagctaaat
    15361 ccagcacatg ataacctgct tccttaatag catccataac ttcaacagga gcattaaaga
    15421 gaagataacc cgctaaataa tgatccttat taatggttcc ttcaaaatca ccaatagcta
    15481 aatctgcttg cttgagccaa ggagtcacat actcaaaatt ttcatgaaag tcataggtac
    15541 cgtcttcttt tttagctgaa aagaaaagtc catcgtggta gagcaaatcc ccgtgggcca
    15601 taattctggc agttttttcc tcttcctact cctgagactt ttgcttagtc ccctcttgag
    15661 aaatagtatc tcgtttttga ctagtcaagg gattccttgg aagctttcaa acaacaagac
    15721 caagcccatt gataaaccaa ctgcgagcaa gagtatcgcc acaaatccct tattgctcca
    15781 cttgcgataa ctcctaaaaa gtttaccaag cccttcataa aacgaaaagc taaaccaccc
    15841 tgatttcgat tttgtcttct ttgtatcttc attctcccta ctttcttatg caagcctttt
    15901 ctttttatta tatcacagat aagtatttct ttcacaattg aattgaactt cccatctatt
    15961 ttctataaat cctaaatgcc ataatgcttt caattcttgt cattttgtga tatcatgtag
    16021 aggtaatgaa aggaaatgaa ctaatccaca gtggcttatt ccaagtatac cacttgggct
    16081 ttggcagtag ttaactgcac taaacataat ataaggagag aaaatgtctg caatagaacg
    16141 tattacaaaa gctgctcact taattgatat gaacgatatt atccgtgaag ggaatcctac
    16201 tctacgcgcg attgctgagg aagtcacttt ccccctatct gaccaggaaa tcatcctagg
    16261 cgaaaagatg atgcaattcc ttaaacattc ccaagatcct gtcatggctg aaaaaatggg
    16321 actccgcggt ggtgttggac tggctgctcc ccagttagat atctcaaaac gcattatcgc
    16381 tgttttggta cctaatattg ttgaagaagg cgaaactcca caggaagcct acgatttgga
    16441 aggcattatg tacaatccaa aaatcgtctc tcactctgtt caagatgctg ctcttggcga
    16501 aggagaaggt tgcctgtctg ttgaccgtaa cgtgcctggc tatgttgttc gccatgcccg
    16561 cgttactgtt gactactttg acaaagatgg agaaaaacac cgtatcaaac tcaaaggcta
    16621 caactccatt gttgttcagc atgaaattga ccacattaac ggtatcatgt tttacgatcg
    16681 catcaatgaa aaagatccat ttgcagttaa agatggttta ctgattcttg aataaagaaa
    16741 atcccgttgc aagacggggt tttgtgttat aatagaggca tgaaaacaaa tgatattgtc
    16801 tatggtgtcc acgccgttac cgaagccctc cttgcaaata caggaaacaa actctacctc
    16861 caagaagatc tccgaggtaa gaatgttgag aaagtcaagg aactagctac agaaaagaag
    16921 gtgtccattt cttggacatc aaaaaaaaat ctctctgaga tgactgaagg tgctgttcat
    16981 caaggttttg ttctacgagt gtctgaattt gcctatagcg agctagatta catccttgca
    17041 aaaacacgcc aagaagaaaa ttcacttcta ttgattctag atggtctaac cgatccccat
    17101 aatctgggtt ctatcttgcg aacagccgat gcgaccaatg tttcaggtgt catcattccc
    17161 aagcaccgtg ctgtcggagt aactcctgtc gttgccaaaa cagccacagg tgctattgaa
    17221 cacgttccaa ttgcccgagt aaccaacctc agtcaaacct tagataaact caaggatgaa
    17281 ggtttctgga cctttggaac ggatatgaac ggtactcctt gccacaagtg gaatacaaaa
    17341 gggaaaatcg ccctcatcat tggaaatgaa ggaaaaggta tctctagcaa cataaaaaaa
    17401 caggtcgatg aaatgattac cattccgatg aatggacatg ttcaaagcct taatgccagt
    17461 gttgctgcgg ccattctcat gtacgaagtt ttccgaaata gactataaaa aagtttccag
    17521 tcatctgatt ggaaactttt ttatgattaa ctatgttctg taatgaattt ataggcttct
    17581 tgaccagcga tagctccatc tccaactgct gttgttactt ggcgaaggtc tttcaagcga
    17641 acatctccaa ctgcaaagat accgtcgact gcagtcttca tgtggctatc tgtcacaatc
    17701 cagcctgcct gatcttggat attcaattct ttaacaaaat cgctaagagg gtccaaacca
    17761 acatagataa agacaccacc gaaggcttgc tctgtcactt gacctgtttt cacattttca
    17821 aaaacgacag attctactct gttttcaccc ttgattttcc ttactacaga atcccatata
    17881 aagctgattt tctcattggc aaaggcgcga tcttgtaaaa ccttttgggc acgaagttgg
    17941 tcacgacggt gaacaatggt aacagtctta gcaaaacgag tcaagaagag ggcttcttca
    18001 acagctgaat ctccaccacc aactaccaat aaatcttggt cacggaagaa agcaccatca
    18061 cacacagcac agtaagaaac accacgactg ttcagttctt cttctccagg cactcccaaa
    18121 ggacggtgtt tagaaccagt tgctacgata actgtacgtg tttcatatgt ttggtcatca
    18181 gtcatcactt tcttaaaatc accatggtct tcgacatttt caacataacc ataaatgtgc
    18241 tcaacaccaa gattttcaag tggttcaaac atcttttcag ccaattcagg tccactaata
    18301 ttagcgtatc ctgggtaatt ttcgatatca gatgtattat tcatctgacc acctggcaga
    18361 ccaccttcaa tcaaagctac ttttagattg cttcgagcag catacaaggc cgcagtcatc
    18421 cctgcaggtc cagcaccgat aataatagta tcgtacatat agattccttc tttcttgttg
    18481 taactatctt tattctaact ctttcttgtc aatcacgcaa ggattatgcc ttgaaaacaa
    18541 gaattaaact cataaccgca aaggataata ctgggacaac caagactcca atcataatca
    18601 tatcatagag atgggcttgg cgagccttgg ctgtcttatc aactcccgac atggctctca
    18661 gaccaatcca aatccctaaa aaaatcagaa caaggatggt ggtcaagatc aaactctcga
    18721 aatataaaga aaatagttgc agtagcatga tttctctcat ttctatcttt tttaaagagt
    18781 aaactcagct agtccaacta actgagtttt cctttatcta ttatatcaaa tataagtccg
    18841 tttgtaacta gcgaagaatt cttttgtccg ctcttcttta ggggtgtgga taatctcatc
    18901 cggagttcca gactcgatga ttttcccctt atctaagaag agaatcttat ccgcaacttg
    18961 ggctacaaag gacatgtcat gactgaccaa aatcatggtc tgacctgact tagcagcatc
    19021 tgcaatagac ttttctactt caccgaccaa ttctgggtca agggctgaag ttggttcgtc
    19081 taagagcaaa acatctggtt tcatagcaag cgcacgcgct agggcaaccc gttgcttctg
    19141 tccacctgat aaatggcgag gataatggtt ttcacggtcc gaaagcccaa ccttagccaa
    19201 ctcttccttg gcaatcttag tcgcttcttg gtcagataat ttcttgacaa caaccaagcc
    19261 ttctttcaca ttatcaagtg ctgttcggcg ttcaaacaaa ttaaactgtt ggaaaaccat
    19321 agacaactta cggcgtaggg caaggatttc ttcttgagtg attttagaaa aatcaactga
    19381 aaaaccatca atctgaatag agccactgtc aggtgtttca agataattga gactgcgaag
    19441 aaaggttgat tttccagctc ctgaagaacc aatcaaggct acaacttccc ctttttgaat
    19501 atccaagtcc agatgatcca agacagtctg tcctgaaaag gatttgctta aattcgaaat
    19561 cttaatcatt aacgaaggtc tcctttcaca tctgtttgca ctgtatcagg tgcagaaata
    19621 gccatttttc tctcgatgaa acgaccgaga ctttcaattc cgatattgac tacccaataa
    19681 acaagggcaa cggagatgaa gcgttcaaaa tagcgataat cagctccacc tagaatctga
    19741 gcttgggcaa agacttccac aacacccgca ctaaaagcta gagatgttcc cttggtcaaa
    19801 ccgatgaggg aattaatcaa ggttggagta gctaccaccg ctgcattagg aataatcact
    19861 cgtcgataaa cttgcgctcg ggtcataccc agactgcgtg ccgcctcaat ctcaccagga
    19921 ttaactgaga gaatggctgc acgaatggtt tcactagcat aagctgcctc attaaaggca
    19981 aaggcgacaa tcgcaaaagc tgcagctgga atcgcattga tattgagacc agttccccat
    20041 tgctgattga gggctttcaa agccaaaggg attccgtagt aggtcaacat gagttgcacc
    20101 aaaatcggtg tcccttttaa gaaactaaca aagaaggcct gcaagggata taaaatcttg
    20161 acacgattga tcttcacaat ggcaaaaaga agcgccaaaa ccaagccaaa aagggcacca
    20221 ccaattgtca acataattgt tgttggaagt tgttggacaa ttctagggat tccatcaaag
    20281 accgaacgta ggctaaacag cttgccattc ggaatcaatt gcatcaagtt ttggtaccaa
    20341 tctgatgcta aaatcgttgt aacattcata aaaacatcct cttctgataa tgattcattc
    20401 taccatgctt ctgccgtcaa tgaaattatt tgctacggtc agatacagac tttgtctacc
    20461 tactagttta tcatactttg aaacagggaa gttatatatt ttatctatca aagagataga
    20521 taaaaactat ttcagtccca gttcttcata agattttcga taaccgattt gcttaacggt
    20581 tccattttct actaaaatgg gccgttttaa caacataccg tcacttgcta gcaactcagc
    20641 cgcttcttgg tttgacaaac ttcctacctt atcttttagc cctaattcac ggtatttgat
    20701 accactggtg ttgaaaaatt gcttcaattc aaatcctgag gtttctagcc aattcaaaat
    20761 gacttcttgg ctaggtgttt cttccacgat atggacggct ttatagtcca cacctaattg
    20821 atttaattct tgttttgctt ttttacaagt tgaacatttg gggtattcga taaattctaa
    20881 catgtgcttc tccttctatt gcttctatct ttaaaatcta ctccttcatg ctccaagagc
    20941 caagctttct tttccactcc tgcagcataa cctgtcagac gcttgcctgc tcccaacaca
    21001 cgatgacaag gtactaggat agaccaagga ttgcgtccca ctgctccacc aattgcttga
    21061 gcagaagcca cttgcaggtc ttgagcaatt tgtccatagg tcactgtctg accataagga
    21121 atgccctgta aatagtccca aactctcttt tcaaaattcg ttccgattgg cgccaagagc
    21181 aagttggata aatcctgagg cttgccttta aagtaatcat ctaagcaagc aataactggg
    21241 tctaaaatag gatgactaac aacttcttct atcgtttcat ctcctagtcc cctctcaaaa
    21301 tgcttctgct cctgaaccca aattccatac aaataatggt catcagctac aagtgataga
    21361 ataccaattg gtgaggagta gagtattttt acatacttct tttgcattat ttctttaatt
    21421 tttgataggc caagcgttcg ccatctactg gcaccttacc aacttgttta aaaccaagtt
    21481 tttcaaaaat atgttgcata accttgtttt cagcatgcgt atctgagcga aaatcaagat
    21541 aatcaaaacc ttcaatcaag ccctctaaga aggtttgagc aactcctttt ccctgcacat
    21601 ctgctgccac agcaatacgg tgaaagacta gatactctga ctctccagct tgccagtttc
    21661 cctcataaat agcttcatag gcctcctctg gactcttggt cacagcagca taggctagca
    21721 gttctccctc ttccaaggct acgtaggctt gccctgagat gatatcatcg ataataacat
    21781 ctgcatttgg atagccattt tgccactggt cactaccagc atctgctaaa cattttttgg
    21841 catcctccat cacctgcatg atggcatcta cttcatttgg aaaagctaaa cgaatttcca
    21901 tcttttttcc tcatttctga ctagtttctc ccatcatagc ataatttaag tatttctaca
    21961 agcagttaaa acttgacttt gtgtttttgt tattttataa tctagttatc aaaactatat
    22021 aaaaaggagt tgaaaatgaa aactaccttt tcctacccaa aatgggcaga aattccaaac
    22081 attgacctct atctggacca ggttttgctc tatgtcaatc aggtctgcgc ccctatctct
    22141 cctaataaag acaagggcct aacagcatct atggtcaaca attatgtgaa aaatggttac
    22201 ctgacaaagc ctgacaaaaa aaaataccaa cgccaacaga ttgcccgttt gattgctatc
    22261 acaaccctca agtctgtatt ttctattcaa gaaatagccc agacacttaa tactctacaa
    22321 actcaagcaa gttcagacca actctacgat gcttttgtgg actacatgaa ccaaggaatt
    22381 gacccagcta accctattat ccaaaccagc tgccaaaccg ttaaactcta tcatcaaact
    22441 ctagacttaa tcgatcatac tcaagaggag gtaatccaat gaacactagt cttaaactca
    22501 gcaaacaact cagttttgga gaggagattg ctaatagcgt gacccatgct gtgggtgcag
    22561 tcatcatgct tatcttgctg cctatttcat ccatctatag ttatgaagca cacggatttt
    22621 tatcctctat cggcgtttcc attttcgtca tcagtctctt tctcatgttc ctatcatcca
    22681 ccatttatca ctctatggcc tatggttcga cccacaaata tgttttgcga atcattgacc
    22741 attctatgat ttacgttgcc attgccggct catacacgcc cgttgtcttg accttgatga
    22801 ataactggtt tggctatctg attattgtca tccaatgggg aacgaccatc tttggtattc
    22861 tctataaaat ctttgctaaa aaggtcaatg agaaatttag ccttgctctt tacctgatta
    22921 tgggctggtt ggttcttgct atcattcctg ccattatcag tcaaacgaca cccgttttct
    22981 ggattctcat ggtaactggc ggactctgtt atacagttgg agctggattt tatgccaaga
    23041 aaaaacctta tttccacatg atttggcatc tctttatcct agctgcgtcc gtactccaat
    23101 acatcgctat tgtttattac atgtaaaaaa gttgagaaat tcaatctcaa cttttttctt
    23161 tacacatatt gataaagtac tggtgcaagc gcacatcatc agtcaattct ggatgaaaag
    23221 aacttaccaa catatttttt tcttgggctg caacaatttg attgttcact gttgctaaaa
    23281 tttctacacc ctcaccaaca ctactgataa tcggaccacg gataaaggtc attggaatct
    23341 tgccaactcc cttacattct gcttccgtgt agaaacttcc taattggcgc ccataagcat
    23401 tacgctcgac caccatatcc atagttccta gatgactctc tttctgagaa gtgatttcct
    23461 tagccagcaa aattaagccc gcacaggtcc caaacactgg taagccagat agaatggctt
    23521 ctcggatggg aagtagcatg ttctggtcac gtaagagctt gcccatggtt gtagactcac
    23581 caccaggcaa aatcaaaccc gacaagtcac tctgatcttg ctgaaaatca tctagatttc
    23641 tgagttctac actctcgaca cctaattgat ctagcacttt tgcatgttct gcaaaggccc
    23701 cttgcaaggc caatattccg attttcatct attttcctcg ttcagccatg agaatttgga
    23761 tttcattttc attaatacca accatggctt ctcctaaatc ttcagagatt tgagctagga
    23821 tttgaggatt acggaagtta gtcacagcct taacaatggc actcgctcgt ttaacaggat
    23881 ctcctgactt gaaaatacct gaaccgacaa agaccccctc tgcccctaat tgcatcatta
    23941 acgcagcatc tgctggcgtt gcaacacctc cagcagcgaa atttacaact ggcaattttc
    24001 catgttcatg aacatattgg accaattcta cagggacttg caaatccttg gcagcaacat
    24061 aaagctcgtc ctcacgtaag ttttgaatgc ggcgaatttc ctgattcatc atacgcatat
    24121 gacgaacagc ttggacgata tcccctgtcc ctggttctcc tttggtacga atcatggaag
    24181 caccttcagc gatacgacgc aaggcttcac ccaaatcctt agcaccacag acaaaaggaa
    24241 cttggaattc tttcttgtcc acatggaaac ggtcatcagc tggagataga acttcactct
    24301 cgtcgatata atcaatttca atagcctcta aaatctgagc ttcaacaaaa tgcccgattc
    24361 tgaccttagc cattactgga atactaaccg cttcttggat ttccttaatc atctttgggt
    24421 cgctcatgcg ggaaactcct ccagctgcac gaatatcagc cggaattcgt tccaaggcca
    24481 tcacagctgc cgcaccagca gcttctgcga tacgagcctg ttcaggattc tgcacatcca
    24541 taataacacc acccttgagc atctgtgcca agtttttatt tagttcataa cgattttcag
    24601 tcatttgttt tatcctcatc atttgtattg gtagctacct tttcatttta agtcagaaca
    24661 gaatgaagca caagataaaa aaactataat tgtatgggga cagattggct aaaaactatc
    24721 tgaccttaac ttaaggccag atagctcatt catttttatt tttcagccgt aagggcagcc
    24781 attgtgatgt agttgtatgg tttgttgaag tgtggcaaga agaagaggtc tgtcaatgcc
    24841 aatttatcaa ttgtcacatg ctcttggata gcaagtgaga acatgtggat tcccatgcta
    24901 attgcaatat catgtgaaac catttgggca ccaagaattt cacggctatc tttgtcaaag
    24961 acaatcttaa ttgctacttc atggttgtca tgtttcatga attctggttt ttgaagatcg
    25021 ttaaagcctg tttcagttgc gttgtaacca gcagctttcg ctttttcaag agtcaaacca
    25081 gttgaaacca tgtgaagacc gtagattgag ataccatttg aaccttgaac accgattcct
    25141 tccaattcat gtccacaagc gttgtaggca ccaacgatac cagtgcgaac agcatttgaa
    25201 gcaagagcga tatagcttgt atctttacga gcattgtcat aaacagtcgc acagtcacca
    25261 acagcgtaaa cgcctgggat agatgtttct tgtttcttgt ctacaaggaa ggcaccgttg
    25321 cggaagagtt cgatcttacc atcagcaagg gctgtgtttg gacggaaacc aactgcaagg
    25381 ataaccatat ccacgtcaaa gctttctttg tcagtaatca agcgttcaac tttaccgtca
    25441 ccttcgattg ctttaacagt ttgacctaga gccaagcgga tgttgtgatc ttccaagttc
    25501 ttcgccatca tttgtgtgaa gtctttgtca tagtaaccgt tcaagacagt atcaacgata
    25561 tcaacaagga caacttcttt tccaagacgt ccaaaggcct cagcaagttc aacaccgatg
    25621 taaccaccac caacaacggc gatacggtcg aggtgttggc tcttgtcaga aagtttattg
    25681 ataacttctt cagcattttg gtacaatttc acgaattgta cgttttcaag agttgcttta
    25741 aattcgcggt ttcctttaac aatttcaaca ccttcgattg gtggcaagat tggtgtagaa
    25801 cctgtagcga aaatcaattt ttcgtatgat tctttgtgct cttttccttc aacttccgct
    25861 gtaactactt tgttatcata gtcgattgaa agaacaggtg agttcatgta aactttagca
    25921 cctttagctt ccaatttttc tttatcagaa tagaacaagc cttcagcacc gtcaatttgt
    25981 tcaccaatcc aaagagccat tccacatcct aggaaagaga tgttagagtt ttggtcaaat
    26041 acaacaattt cgttctcatt tccaaaatta tccaacatgg tattgataca tgctgtacca
    26101 gcgtggttag caccgactac aacgatttta ctcataaaaa tttcctgcct tcattctaaa
    26161 tttaccttac tagtatacca tttaccgtta gcgtttacaa ggggggtact attatttcag
    26221 cattttttat caaaaataat tccccattta tcctgttttc aagcctcatg aattttatga
    26281 gcatatttct tgactttttc caaattttgt ttgtgaaaat tctaacttta tggtattata
    26341 ataacatgaa aataaaatgt aagggcttca atttagatga ttatttgata ttacaactta
    26401 ttttctataa gagaaaggag ttggtagctt gactcttcgt tcacattctg aacggctaat
    26461 ggggactact atcactattt cattagtgga tgagcaagcc gatatctttc tccaaaaatc
    26521 ctttgacttg ctcaaagagc ttgaataccg cttcaacgcc aatagtcaag aatctgagtt
    26581 gatggaaatc aattatcaag caggaatatc ccccgtcacg gttcatccag acctgtttga
    26641 gctgatttca cttgggttag agcatagcct agcgctctct agccacctca atatcagcat
    26701 tggtccctta attcaaacct ggcgtatcgg tttttcagat gccaaggtcg cccagcctca
    26761 agaaattgaa tcggtgctgc ctctaatcaa tcctcatggt atcgagttag attcttctac
    26821 ttctactgtg tttttaaaac agaaaggaat gaagatcgat ctaggttgtt tagccaaagg
    26881 atacagtgcg gataaggttg cccaatttct taggaaagag ggggtgactt ctgccttgat
    26941 caatctggga gggaatatcc tgaccattgg aaaaaatcag gcaagagggg ataacccatg
    27001 gcaaatcggg attcaagacc cagccaatcc gaggggaaat catttaatga ccatccctgt
    27061 tgtcaataaa tctgtcgtga cttcaggcat ttatgaacgt cacctgaccg tcgatggaca
    27121 agattaccat cacatttttg acagtcaaac aggatatcct gttgaaacgg aactagcgag
    27181 tctaacaatc atctctgata aatcagtcga tggcgaaatc tggacgactc gactctttgg
    27241 agaaagacct gcttctatcc tctggcaagt cgaaagtttg gagggcatcg aagtcatcct
    27301 catcgataaa gaaggccacc taagctgttc ttcaggaatt cctactctat agagacaact
    27361 gtttcaatgg aattttaaaa ttgtattatg taaaaagaga aaggaaatct catgttaaaa
    27421 cttattgcta ttgttggaac aaattcaaaa cgttctacaa accgtcaatt gcttcaatac
    27481 atgcaaaaac actttgctga caaagctgaa attgagcttg ttgaaatcaa ggccattcct
    27541 gtcttcaaca aaccagctga caagcaagta cctgctgaaa tattggaaat tgctgctaaa
    27601 atcgaagagg ctgatggcgt tattatcggt actcctgagt atgatcactc tattccagct
    27661 gttttgatga gcgctcttgc ttggttgtct tatggtattt acccactttt gaacaaacca
    27721 atcatgatta caggtgcttc ttacggtacg cttggttcat ctcgtgccca attgcaactt
    27781 cgtcaaatct tgaatgctcc tgaaatcaag gcaaatgttc ttccagatga attcttgctc
    27841 tcacactctc ttcaagcatt taacccaagt ggcgacttgg ttgaccttga tgttatcaag
    27901 aaattggatg ccatctttga tgacttccgt atcttcgtga agattactga gaaattgcgc
    27961 aatgcgcaag aattgcttcg caaagatgca gaagaatttg actgggaaaa tttgtaagat
    28021 aggagaccga aagaatgaaa tttgttggac ttgttggatc aaactacgat caatcatata
    28081 accgcaaact cttggaattt atccgtcgca atttcaaatt caaatttgaa ttagaagtac
    28141 ttgaaatcga cgaagttcca atgtttaacc aagacgaaaa atgggatgaa agtttccaat
    28201 tacgttattt atataacaaa attactcgtg cagatggtgt tatcattgct actcctgagc
    28261 ataaccacac tatctcagct tcactcaaat ctgtacttga atggctttca tacgaagttc
    28321 atccatttga aaacaagcct gttatgattg tgggtgcatc atactatgac caaggaacat
    28381 cacgtgctca agttcacctt cgtaaaatcc ttgatgctcc aggtgttaat gcctacacgc
    28441 ttccaggtaa cgaattcctt cttggtaaag ctaaggaagc ttttgataac aacggaaata
    28501 tcaccaacga aggcactgtt aaattccttg aaacttgctt agataacttt gttaaatacg
    28561 taggagtcgt ttcgaaattg aaaaaaccaa aaccaatcga atcagaagac ttggattgtg
    28621 gaaaaccaat cgctacaacc atcacagaag ttgaccctga cgatccagaa tgggtagaaa
    28681 aagttgcagc aatcactggt gctgtttctg gtgataccta tgtcaaattg gaccacggta
    28741 tcctaacagt taaccaaatt gatatgttct tgaaagctat gccatttgaa ttgacatacg
    28801 ctgacgacaa caaccaattc ctctactaca acaacgctca ccaagatcca gacactatgt
    28861 tcgctaaacg tgtaccacct caatcaggta gccgtatgtc gactgttcat ggttctcttc
    28921 caccagcacg tatgaagaac gtagagtggg ttatcggaac acttcgcaac ggaaaccaag
    28981 aatacgtccg tacgatcgtt ccaggttctc ctgcaggtgt tatcaacact cacaactacc
    29041 aagcaatgta ctatcctgat ggatcatacg ctggtatcaa tgaaatcgtc tttaacttcc
    29101 aaccatggct tgactggtac ctaaaagaga ctggtcaacg tttggtgggt ggtagcggac
    29161 catttgctcc tgctggcgga catggtcacg gcgatgcaga tgcaacatct ggagcttctg
    29221 atgcaggtga tgctggaggc cacggtggtg gcgcagatgc cacagccggt gcaagttact
    29281 aatgatagtt tttaggaacc attatggttc cttttttagc gaaaaaagac tagcaaacac
    29341 aaactgctag tctctttgtt atcgtttcat ctatctttgt taaaagatag aatacatatt
    29401 atgaatttgg gtcatcaaga ctacggccat gtaatccttt ttcacgttgt acttggcgta
    29461 gtttttctgg tgtaacatcg tttccttctt cgtccacaat tttgattcct tcaatatggt
    29521 gacgaacagc gcggcgataa ccttcgatgt actcctcacg tagtttggct tgttccactt
    29581 tttcttctgg tgttaagcct tctgtttttt tctttttagc aagctcattg atacgagcaa
    29641 tttttttcgg atccatttct tctcctctgt aataagataa agcccgttta tcaaatttta
    29701 tttagtgtta atttggttaa aacaagcaaa cttagctgct ttcttggtta gttgtgacaa
    29761 gattgccaaa cgattttgac ggacagcctg atcttcagcc attaccatag tattttcaaa
    29821 gaaagcatca atgactgggc taagcgcaaa gagttgtttc aattgctgac ttgcaggtcc
    29881 tgataaaacg agtgtttcta ctgcttctgc caaagctttt tcttggtcat tctcaaatag
    29941 tgctgaatca accgtagcaa ccccttctgc cttctcagcc aggttaaagg cacgagaaag
    30001 tgattcaaca gatggtttaa aatcttcttc cttgcttact tctacgagag cacttgctgc
    30061 ttccaacata tctgccacaa caaagtttga acctgcaaga actgcttctt tgatatcttt
    30121 tggagtagag cccatcatct tatcaacacg agccttgata aagtccataa cctctgcttt
    30181 attttcataa gtcaaactgt caaatttcaa tgcataaagg ctatcaatca gctcatccat
    30241 agcaatgtgc caaccaaagg catccaagat acgaaccaca ccttgagttg cacgacgaag
    30301 ggcataaggg tcattagaac ctgatggaat caatcctact gagaagaaac tcaaaatcgt
    30361 atccaatttg tctgcaatgg ctagaactgc accgaccttg ctctctggaa gttctccttc
    30421 agctgatgta ggcatgtagt gttcacgaat agcagctgcc accgctggag tttcaccagc
    30481 aagaagggtg tatttttcac ccataattcc ttggagttcg tcaaattcac caaccatacc
    30541 tgtcaacaag tcaaacttgt aaatggctgc tgcacgagca aggtcaactg tttcatccac
    30601 tgacaaacca gctttttctg ccaaaagtac agtgatttga cccgtacgaa tcatgtgttc
    30661 acgaagggaa ccaatcttct catggaaggt gacattgttt aatttttcaa caagatctga
    30721 aatcaccaat ttttggtctt cacgccagaa gaattctccg tcttccaagc gggctaccaa
    30781 gactttttca tttcctttga tgacattttt caaacgctct gcgtttccgt tacgaacaga
    30841 aatgaagttt ggcaagagtt ttccatcttg atcacgaaca acaaagtaac gctggtgttc
    30901 cttcatagaa gtcaccaaga cttcttctgg aacttcaagg tatttagcat caaaacttcc
    30961 catgaaggca gttgggtatt caaccaaatt caagacttca ttcagcaaat ccgcatcaat
    31021 ttcgatacgt acaccatgtt ttgcctcaat ttccttgatt tggtcaacaa tcatttgctc
    31081 acgttcacat ggatctgcga ttacaaactg cttacgaagg tcttcttcat agctcaatgc
    31141 tgactgaatt ttggtttctt tccccaagaa acgatggcca cggctcacac gacttccctt
    31201 gatatcaagg aaatccaagt caaactcttg ctcatccaag agaacagtta aagtgtgaac
    31261 agggcggatg tattcaaagc tatttccagc ccagtgcatg ctgacaggga aagtcaatga
    31321 cttcaagaca tctacaacac caggaacaat ggcttcaact gattggccaa cttcttcctt
    31381 agtgacatag acatattctt cacccttaat ttcacggaat tcgatatctt caacagtcaa
    31441 acctttccca cggacaaatc cttgagctgc tttagtgaag tttccatcac tatccaaggc
    31501 aattttcttt gctggtccct tgaaatcttc tgtcaaatca gactgtttgt ctgataaacc
    31561 agtcacacga acagccaaac gacgtggtgt tgagaaggtt tgaatggctt caaaagacag
    31621 gcggttttcc ttgaggaagg ctgccatttt ttcgcctagt tgtttttcac ttggtgtgac
    31681 aacataggct ggtaattctt caagaccgag ttctactaat aagttttttg tcatgttttt
    31741 tctccgaaaa gtatcttttt attttccagt ttgccttatg tgattggcac gcaagcaacc
    31801 aacttcgttg tttcattgct aaaattggag ccaaaagtct ccaattttgc ctagtatcct
    31861 tagtttcact aaggatacct tcatcactgc ggcaactggc tcagggctca ctctgttcgc
    31921 ccattttcgt aatttgtcac tctctttatt ctgcgtcttc tgctaggagt ttagctcttg
    31981 tttcttcatc caaaagtggg tagcctaggc gtttgcgttc tgcgacaaag gttttggcta
    32041 cgacacgggc caagttacgg atacgagcga tatagcctgc acgctctgtt acagatacgg
    32101 caccacgcgc gtcaagcaga ttaaaggtat gtgaacattt gagaacatag tcataggcag
    32161 ggtgtaccaa gccttcttct aatgcacgac cagcttcttt ttcaaactta tcaaagtttt
    32221 caagcaacat ttcttggtcc gaaatttcaa atgaatattt tgagtgctca tactcaggct
    32281 ggataaagat ttctccgtat tttacaccat cagcccactc gatatcatag acagagtcta
    32341 cttcttgaat gtaagaagcc aagcgctcca aaccataggt aacttccgca gtcacagggc
    32401 cagttgccaa tccaccgact tgttggaaat aagtgaactg agtgatttcc attccgtcaa
    32461 gccaaacttc ccaaccaaga ccagctgaac cagttgatgg gttttcccag ttgtcctcaa
    32521 caaaacgaat atcgtgctcc aaaggattga ttcccaattt ttccaaagat tcaaggtaaa
    32581 gttcttggat atttgatgga gaaggcttca tgaccacctg gaattggtgg tgttggtaga
    32641 gacggttagg gttttcccca taacgaccgt cagcaggacg acgtgatggc tctacataag
    32701 ctgcattcca tggctcaggt ccgatagcac gaaggaaagt gtaaggactc attgttcccg
    32761 cacctttttc attatcataa gcctgcataa gcatacaacc ttggtcattc caaaattgtt
    32821 gcaaagtaag gatgatttcc tggaaagtca atttcttaga cattgtttac tcctttagtt
    32881 tttatatttc tttttcaatt aatttctgct gaacaaacca atctaacaag ggaaaagttt
    32941 tttctgtatt tgcccataaa tgataagaat ctaagaccgc ttgtacacta cctaaatttt
    33001 ctaccaactt atctactgtc aaaaagctgc gccagtattc ataaaaaata cttgcatagt
    33061 tcttatcata agtcgaagaa ccaaaatcat tcaatgaatg ccaaccatac ttcttctgaa
    33121 aaagttctac gagagattga ttacaaattt tttccgcttg aaattcctct tctgtcaaga
    33181 aatacttgcg actaatatat tcaaccatcc cctcttcgaa ccagatataa gagtcataac
    33241 catcaaaatc atctaaaaaa tgctccgacc aatgagctaa ctcatgtcct acaatctgta
    33301 agaggaaatt ttcagataaa gaatgatagt gactttctat tgcttgagtt tgctgagaac
    33361 actcgtagtc catcaattga tacaaataca actctttcca aacagctaaa tcaggcgcca
    33421 taaccattcg tctattattt gtataggctg gaacagcgct ttccctaata atctgtgtag
    33481 cagcattaaa atctgaccaa ataacggctt gcggtaaatc acagactgca agttcattct
    33541 ttaaaaaaga ttgataatct ttcaactttt cagtatttct tactacaaaa tcacgaaatg
    33601 tagctagttg actatcgtct tttacaagat aaaggttgtc cacggctctc ctttctttca
    33661 cacaatagac tgaataagca aaagaaccac atctgacaat cctaggttga tttaacctag
    33721 gggcgtcaga aacgcggttc caccctaatt tattacttca ttgtttttga aaatactaca
    33781 gaaagcgcca gccctttatt ttgccctact tggctcccac tatcccaagc tcgcttgaag
    33841 aacgccataa gactttcttt cctgctgact attatatcaa aaattagaat aatgtacaat
    33901 tctttttatg attttctaga aatccacatc atcaactcgt ggagcacccg attgaacagc
    33961 aatcgttttt aaggtttctc tctcctcatg actcagttca attccaaagc aatcaagatt
    34021 agcttgaata cgagaggttg tgacagattt tggaagtggt aaaaatcctt ctgccaagct
    34081 ccaggccaag gctatctgag caaccgattt tccgtgattt gctgctattt cttggacttg
    34141 cttgctatca aacagttctc cttgtccaaa aggcccccaa gcttccaata aaattccctt
    34201 ttcacgacag taagctacga cttcctcttg atacacacct ggcgccaagc gaacttgatt
    34261 gaccgcagga acgatagttg cagtttcaag caaggcatcc aaatgatggg gaagaaaatt
    34321 gctaacgccg atagcacgga ttttcccttc ttgatagagg tcttccatcg ctctccaaac
    34381 ttccgcattg cgagttttcc atgcgtcatt ttctctgagc ggttttgggt tcggccaatg
    34441 aatcaaatac aaatccaaat aatccaagcc cagtttttct atagattttt ccaaagcttg
    34501 acgagtttgc tcataggttt gctgactatt ccaaagcttg gtagttacga acatttcttc
    34561 acgtggaact ccgctatctt tgattgcttg accaacactt tcttcattct gataaatcgc
    34621 cgccgtatca atatgacgat aaccagcctt caaggcttct aacactgcat gataggcttc
    34681 ttctccatcc ttagccttaa aagttccaaa tcccaatact ggaatttcta ctccattatt
    34741 taattgatag gtattcatat gcttctcctt ctattttatt catcaattat agcataaaac
    34801 attttttaag tagtactatc ttctgtaaaa aataagtctg tcaaatatct aacagaccta
    34861 ttttttcttg cttattcatc acgactatag tacagctcat gagcttttag gcgagtattg
    34921 agcatctctg gtatggtcac aaaggtataa ccttgatttt tcaaatactc aatgaccctt
    34981 ggcaaggcat tgactgtcgg actgtgaata tcatgcatca aaacgataga gccgttagct
    35041 acttgatgct gaatttctgt caaaatagat gcttcatttt tactcttcca gtccagacta
    35101 tccacatccc acatgataaa gctcaaatcc aagctattgc gaatatcatc tgtaatagca
    35161 ccataaggtg gacgcatgag tttagaacta gaacccagca ctttagttag cacatcctca
    35221 gtatcagtaa tctgcttttt agcttcatca agagagagtt gcgagagaat cggatggctc
    35281 caactatggt ttccaacaac atgaccttca gattttatcc tcttcaccaa gtcctcattc
    35341 ccagaaacat ttttcccaag cacaaagaaa gtcgctttaa tatcatattt agctagggtc
    35401 tctaatacct gcggggtcgt tgctggattt ggaccatcat caaaggttag agcgacaact
    35461 ttttgatatt tcttatcaaa gtaagattgg tacaaggccg catctttttc gagtaagtac
    35521 gaagattgga taacatcaaa gaaagcagat actggcaagg ctatctcttc taaattttca
    35581 accacaggac ttggataaag gataatctga ctatccttgt aatcaaaatt ccatgcagac
    35641 aagtcttggt cagagaagtt ttttacaatc tgctcactct ggtcttgctc tattttttta
    35701 tcctctatga aggaggtcaa ctcttttatc agctgttcct tagccttact agcatctgaa
    35761 aacagttggt caagtgtaaa aggttgccca tcttctgtta agtgaacctt tcctagactg
    35821 gtcttttcag tctcttcaac cttaaaagca actaaatcat agatttgttt ggtcacatta
    35881 cgattaacga ctccctttaa acctgactct tcttgctctg tatagtagaa aacaagattg
    35941 tccttacttt ctagcttgtc cttaacatct tgatttatca actccctaac agaggaaatc
    36001 actttctccc cttggagagg ataataggca atcacttcgg cttgcccctg acgaaaatgc
    36061 tccttctgat ttccctcact caattgatca tctttctctt ttttgagcga ttcaatcttt
    36121 tgctcaaaac ttttttgctg gtagatctta aaagcaataa atccgcctaa taggcaaata
    36181 gaaattgcta aaataccaat caaagccaat aatacatgtc tcgttttccc gtgtctgcca
    36241 cgtcccagtc tacttttatc catatttata tcataacaaa tttgagcaat aatttcaatg
    36301 atacaatttg gcaatccaca attcctctag caagccaaag catcttacat caactccaac
    36361 atccgtatct gtagagatta tgtagttttc tatctatgga atttctagta gattgaagct
    36421 agaatagtag acctatactt ctaaaacatt gttagaaatc gattttactg tcctgatcga
    36481 tttgtcctat tctcatttca ttttactata aaactatgaa aagctaggtc atctgagaag
    36541 taattactat cgacaattgc gatagcgtat actggtgcga tttgtttgta gctctggtgg
    36601 gtatcacctt cacgttggcg aattttttct aggttttgat taacctgact gcacagataa
    36661 gcccataggc gattgatgaa aaaattctga tgatgaatct gaatttcgat gataacttgg
    36721 attccattat ctaactccgc caagacgtct atactagtat agaaatcctg cactgagtag
    36781 ggcatggaag gcaagacgtg aatgttactt ccctccaaaa tcgtcacatt ttttgctggc
    36841 aagtccagca tatcgcggat aaattgacaa atcattagtt tggctgatac ccggatgtct
    36901 gagaatcctc cttttcctcc ttctattata gcacattttt aaatctaggt ttgctagatt
    36961 ctatgcttct atctatttat tcggaaaaga aagcttttct tcagaagaaa gctaatagct
    37021 tatttgaaat tttctcctct ctgttggata gtcccgtcta tctatgttat aatgaaagaa
    37081 ggatttaaaa tcggaaaagg agtatttatg ctaaaattag gtatcatcgg aactggcgct
    37141 atcagccatc atttcataga agcagcccat accagtggag aataccaact ggtcgcaatc
    37201 tattctagaa aactagaaac tgcagcaacc tttgcttctc gctatcaaaa tatccaacta
    37261 ttcgatcaat tagaagtctt cttcaaatct tcttttgatt tagtctatat cgccagtcca
    37321 aactccttac attttgctca ggcaaaagct gccttgtctg ctggtaaaca tgttattctc
    37381 gaaaagccag ctgtcactca accacaagaa tggtttgatt tgattcaaac agctgaaaaa
    37441 aataactgtt ttatctttga agcagctcgt aattaccacg agaaagcctt tactactatc
    37501 aaaaactttt tagcagataa gcaagtgtta ggagcagatt tcaactatgc caaatactct
    37561 tccaagatgc ctgacttgtt gactggacaa acaccaaatg tcttttcaga ccgttttgct
    37621 ggtggagccc tcatggattt ggggatttat cccctctatg ctgctgttcg tctttttgga
    37681 aaagccaatg acgcgactta ccatgctcaa cagcttgaca atagcattga cctaaatgga
    37741 gatggtatcc tcttctaccc agactatcaa gttcacatca aggctggaaa aaacatcact
    37801 tccaatcttc cttgcgagat ttatacaaca gatggaacct tgactctcaa cacgattgag
    37861 catattcgct cagctatttt taccgaccac caaggaaatc aagtccagct tcctatccaa
    37921 caggctcctc atacgatgac tgaggaagtc gctgcatttg cacacatgat ccagcaacca
    37981 gatctgaatc tctaccaaac ttggctgtat gatgcaggct ctgttcatga gctactatat
    38041 accatgcgcc agactgctgg cattagattt gaggcagaaa aatgaaaacc aaactaccga
    38101 ctgaatggca agaactgagt gaccaactcg gtttccaaga attcaccccc attcaaactc
    38161 aactatttga gccccttctt gctggagaaa acctcctagg agtgagccaa accggaactg
    38221 gtaagaccct agcgtatctc ctaccaagtc ttctcagact acaaaagaaa aaagcccaac
    38281 aactcttgat tctagcacca aatacggaac ttgctggaca gatttttgat gtatgtaaaa
    38341 cgtgggcaga agctatcgga ttgactgctc aactcttcct ttcaggttca agtcagaaac
    38401 gacaaattga acgtcttaaa aaggggccag aaattctgat tggaactcct ggccgtatct
    38461 ttgaactcat taaacttaaa aaaatcaaga tgatgaatgt ggaaaccatc atcctggatg
    38521 aatttgacca attactagat gattctcaga ttcactttgt agaaaaaatc actcactacg
    38581 cacctcgtga ccaccaactg gtctacatga gtgccacgac caagtttgac caagaaaaga
    38641 ttgtgccgaa tacacgcact attgatctct ctgatcaaaa attggacaat atccagcatt
    38701 tctacatgca ggtagaccaa cgtcatcgag tggatatgct acgaaaactg gctcatgtag
    38761 aggatttccg tggtctagtc ttcttcaata gcctgtcaga ccttgggaat gccgaggaaa
    38821 aactacagta tcgtgatata ttggctgttt ccctcactag tgatgttaat gttaaattta
    38881 gaaaaatcat cttagaaaag tttaaagata accaactaac cctgcttctt gcaactgacc
    38941 ttttggctcg tggaattgat atcgatagcc tagaatgtgt cgtaaacttt gatattccta
    39001 gagatagcga aacctacaca caccgtgctg gccgtactgg tcgtatgggc aaggaaggtt
    39061 atgttatcac tctcgtcact catccagaag aaatcaaaaa acttaaaaag tttgcaagta
    39121 tccgagaaat tgtcctaaaa aaccaagaac tctatatcaa ataaagcccc attgctctat
    39181 acacatccag tgtatggagc ttttttataa gcaattcaat tttatactca tctgctttca
    39241 aaaagcattc tagtccatct ccgattaacg atggacttta tcacctcctt ctccagtcct
    39301 tgtatgacat cttgaa
//
LOCUS       DBEJJE010000017        38697 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEJJE010000017 DBEJJE010000000
VERSION     DBEJJE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.17"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL3F5_000871"
     CDS             371..598
                     /locus_tag="ACL3F5_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514703.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL3F5_000872"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL3F5_000872"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0514704.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="ACL3F5_000873"
     CDS             4798..5250
                     /locus_tag="ACL3F5_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0514705.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="ACL3F5_000874"
     CDS             5269..6606
                     /locus_tag="ACL3F5_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0514706.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="ACL3F5_000875"
     CDS             6685..7569
                     /locus_tag="ACL3F5_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0514707.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="ACL3F5_000876"
     CDS             7569..8402
                     /locus_tag="ACL3F5_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0514708.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNRIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="ACL3F5_000877"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="ACL3F5_000877"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0514709.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="ACL3F5_000878"
     CDS             10525..11628
                     /locus_tag="ACL3F5_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0514710.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11802..12500
                     /locus_tag="ACL3F5_000879"
     CDS             11802..12500
                     /locus_tag="ACL3F5_000879"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0514711.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12519..14036
                     /locus_tag="ACL3F5_000880"
     CDS             12519..14036
                     /locus_tag="ACL3F5_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0514712.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14161..15489
                     /locus_tag="ACL3F5_000881"
     CDS             14161..15489
                     /locus_tag="ACL3F5_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0514713.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15741..16607
                     /locus_tag="ACL3F5_000882"
     CDS             15741..16607
                     /locus_tag="ACL3F5_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0514714.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16623..17462
                     /locus_tag="ACL3F5_000883"
     CDS             16623..17462
                     /locus_tag="ACL3F5_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0514715.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17735..18187
                     /locus_tag="ACL3F5_000884"
     CDS             17735..18187
                     /locus_tag="ACL3F5_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0514716.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKEEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18284..18628
                     /locus_tag="ACL3F5_000885"
     CDS             18284..18628
                     /locus_tag="ACL3F5_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514717.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            18638..18847
                     /locus_tag="ACL3F5_000886"
     CDS             18638..18847
                     /locus_tag="ACL3F5_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514718.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YDYKPIDKNRKKSKRKNRFVHGRDL"
     gene            18905..19549
                     /locus_tag="ACL3F5_000887"
     CDS             18905..19549
                     /locus_tag="ACL3F5_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0514719.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSAFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19718..20635
                     /locus_tag="ACL3F5_000888"
     CDS             19718..20635
                     /locus_tag="ACL3F5_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0514720.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20653..21537
                     /locus_tag="ACL3F5_000889"
     CDS             20653..21537
                     /locus_tag="ACL3F5_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0514721.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21553..22404)
                     /locus_tag="ACL3F5_000890"
     CDS             complement(21553..22404)
                     /locus_tag="ACL3F5_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0514722.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22604..24661
                     /gene="pbp2b"
                     /locus_tag="ACL3F5_000891"
     CDS             22604..24661
                     /gene="pbp2b"
                     /locus_tag="ACL3F5_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0514723.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24672..25268
                     /gene="recR"
                     /locus_tag="ACL3F5_000892"
     CDS             24672..25268
                     /gene="recR"
                     /locus_tag="ACL3F5_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0514724.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25444..26487
                     /locus_tag="ACL3F5_000893"
     CDS             25444..26487
                     /locus_tag="ACL3F5_000893"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0514725.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLVYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            26571..27944
                     /gene="murF"
                     /locus_tag="ACL3F5_000894"
     CDS             26571..27944
                     /gene="murF"
                     /locus_tag="ACL3F5_000894"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0514726.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTSFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            27931..28542
                     /locus_tag="ACL3F5_000895"
     CDS             27931..28542
                     /locus_tag="ACL3F5_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0514727.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28633..29337
                     /locus_tag="ACL3F5_000896"
     CDS             28633..29337
                     /locus_tag="ACL3F5_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0514728.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29556..30929
                     /gene="ftsA"
                     /locus_tag="ACL3F5_000897"
     CDS             29556..30929
                     /gene="ftsA"
                     /locus_tag="ACL3F5_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0514729.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30946..32205
                     /gene="ftsZ"
                     /locus_tag="ACL3F5_000898"
     CDS             30946..32205
                     /gene="ftsZ"
                     /locus_tag="ACL3F5_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0514730.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32210..32881
                     /locus_tag="ACL3F5_000899"
     CDS             32210..32881
                     /locus_tag="ACL3F5_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0514731.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLSLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32891..33430
                     /locus_tag="ACL3F5_000900"
     CDS             32891..33430
                     /locus_tag="ACL3F5_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0514732.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33430..33693
                     /locus_tag="ACL3F5_000901"
     CDS             33430..33693
                     /locus_tag="ACL3F5_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0514733.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33690..34475
                     /locus_tag="ACL3F5_000902"
     CDS             33690..34475
                     /locus_tag="ACL3F5_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0514734.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34484..35272
                     /gene="divIVA"
                     /locus_tag="ACL3F5_000903"
     CDS             34484..35272
                     /gene="divIVA"
                     /locus_tag="ACL3F5_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0514735.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35620..38412
                     /gene="ileS"
                     /locus_tag="ACL3F5_000904"
     CDS             35620..38412
                     /gene="ileS"
                     /locus_tag="ACL3F5_000904"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0514736.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELIYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        12072 a         6765 c         8393 g        11467 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtaaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 tttgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgtgacta ttaaccttct cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccgtcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcctt
     4621 gaggttgtag ataagactga cctatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagcca tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gatgctttgg tgccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aattttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccattt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttataac
     7441 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca gttttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctt attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataggattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8461 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8581 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagataaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     8821 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggcaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caactattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag
     9721 gcataatgga aaacaggtcc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcggaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10321 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcgaact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
    11701 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
    11761 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
    11821 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
    11881 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
    11941 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca
    12001 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
    12061 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
    12121 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
    12181 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
    12241 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
    12301 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
    12361 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
    12421 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
    12481 tcgttgctag tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag
    12541 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
    12601 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta
    12661 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
    12721 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
    12781 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttggtaaaac
    12841 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa
    12901 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
    12961 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
    13021 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
    13081 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
    13141 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
    13201 aaactgttgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
    13261 atttggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
    13321 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
    13381 gtcgtaaaaa atacgcgggt ttgtttttgg gagttgcttt aacatctttt attaccggta
    13441 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
    13501 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
    13561 cattttcagg aggtgtaatc gatttcacat tatttggaat tttgcagggg aacgctaaga
    13621 cgaattgggt tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt
    13681 ttagatggtt cattactcaa ttcaacgttc taacgccagg acgaggagaa gaagtagatt
    13741 ctaaagaaat ttctgaatcc gcagattcga cttcaaatac tgcagattat ttaaaacagg
    13801 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    13861 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    13921 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
    13981 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    14041 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    14101 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    14161 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    14221 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    14281 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    14341 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    14401 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    14461 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    14521 ggtaaattgg ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    14581 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    14641 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    14701 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    14761 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    14821 tttatctcta acctttatag tggttctgta acagatgaaa aagttagcaa atatacaact
    14881 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    14941 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    15001 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    15061 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    15121 gaataccttg taaacggatt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    15181 tctaagaaat tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt
    15241 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    15301 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggattt
    15361 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    15421 ccagcagatg ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg
    15481 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    15541 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    15601 aactgtcacg aaattaaaat gaagttctta cataagcgaa ccataaaaaa tttcattttg
    15661 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    15721 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    15781 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    15841 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    15901 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    15961 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    16021 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    16081 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    16141 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    16201 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    16261 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    16321 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    16381 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    16441 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    16501 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    16561 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    16621 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    16681 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    16741 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    16801 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    16861 ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat
    16921 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    16981 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    17041 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    17101 tgaaacaatt tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt
    17161 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    17221 cacttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    17281 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    17341 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    17401 tcttcctagt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    17461 aatactctgc gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt
    17521 gcctgtggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    17581 atcaagatac agaagtatat tttatagatt tagagaatat agaagttata agtgtctaca
    17641 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg
    17701 gttttagtta actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    17761 caccttttac aaagggattc atcccaattt agacaaggct atcgactatc tctaccaaca
    17821 tcgtaaagat tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt
    17881 tgttcaggaa aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta
    17941 tgcagatttg catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa
    18001 agaagaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gttatgaaca
    18061 ctacccactc ttattgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    18121 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaatcttgat
    18181 tgattaaaaa taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat
    18241 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta
    18301 tgctgcaaga gctagtttct tagatggaca ggggattaca gttgatgaga tgtcctggat
    18361 aattaggggc attgtgaatg gattgattgg tagatacata aaattaggta cttatgcagc
    18421 taagtatggt attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc
    18481 aagagtagga ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc
    18541 tgatgtatat ggtaattttg ccaacaatat tgctgtagct tgggatgcac atgataaaat
    18601 ccctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    18661 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    18721 taatgagcat acttggagta ctattttaat tgcttcgctg tccgggatat atgattataa
    18781 gcccatagat aaaaatagaa aaaagtccaa aagaaaaaat agatttgttc atggtaggga
    18841 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    18901 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    18961 catgcgtttt agtgagaagg tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    19021 ttgtttaccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    19081 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    19141 tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc
    19201 agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg
    19261 tttaggtatt ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg
    19321 ttatgaccta tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt
    19381 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    19441 cgccttcagt ctactcttag gtggctcagc cttcctactt tttgggtttg gactattggt
    19501 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agctttattt
    19561 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    19621 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    19681 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    19741 aggtgtcatt ccagccttct acgcatgtta tgatgagcaa ggagaagtaa gtccagagcg
    19801 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    19861 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    19921 catggcggta gccaaaggta aattgaccat tattgcccat gttgcctgca acaatactaa
    19981 agacagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    20041 tccaccaatt tacttccgct tgccagaata ctcagttgcc aaatactgga acgatattag
    20101 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    20161 tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa
    20221 ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggcgggg aagaccatat
    20281 tgtctttaac ggtccagatg aacagttcct aggtggccgc ctcatgggtg ctagggctgg
    20341 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc
    20401 ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa
    20461 gctcacttct gctcatggaa atatgtacgg tgtcatcaaa gaagttttga aaatcaatga
    20521 aggcttgaat attggatctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc
    20581 agttgtagaa gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa
    20641 aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaaccaa catcaagtat
    20701 ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat
    20761 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    20821 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    20881 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    20941 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    21001 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc
    21061 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag taattcagcc
    21121 tgtgaagtcg ggtatatgca tatgcaagat ggagcttttc aggatctcgc ttctacaaca
    21181 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga
    21241 cgtatcttta aggaagctac tgaaggaaac aaaatctgca tggaaggcat tgaccgtatg
    21301 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtt
    21361 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc
    21421 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    21481 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    21541 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    21601 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    21661 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    21721 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt
    21781 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc
    21841 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    21901 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag
    21961 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa
    22021 gtagatacgc tcagcatctt cgattagctg ggcaattcgc tctagttgga tttcgtcaat
    22081 caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg
    22141 actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    22201 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    22261 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    22321 aaaatagcga gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    22381 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    22441 tagatcaggg aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    22501 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct
    22561 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    22621 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    22681 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    22741 ttacgaaaaa aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    22801 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    22861 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    22921 gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt
    22981 ggctgatcct gaaatctata aaaaaacagt ggaagctctc ccaagcgaga aacgcttgga
    23041 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtaca
    23101 aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    23161 aaatgctgtt ggaaactttg cgacaggaac cattgcgaca gatcctctaa atgattctca
    23221 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    23281 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    23341 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    23401 tcgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    23461 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    23521 aggtagtaag ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga
    23581 tgctttactg aaaagttatt tcaattccga gctagaaaat ggtggagcca agtattctga
    23641 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    23701 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    23761 ctttgttcca ggttcggttg tcaaggcggc gaccatcagt tcaggttggg aaaatggagt
    23821 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    23881 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    23941 gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    24001 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    24061 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    24121 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    24181 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaatg atggtgttcg
    24241 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    24301 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    24361 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtgaat tgacaactgg
    24421 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    24481 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    24541 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    24601 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta
    24661 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    24721 taccgggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    24781 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    24841 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc
    24901 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    24961 tccaagaata ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta
    25021 tcagtccgga cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaggttt
    25081 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt
    25141 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    25201 gagcggacat tgagtatgcg gacgaagtga cactcttacg agccattgaa aatcggacag
    25261 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    25321 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggctcagg ttcaagtttt
    25381 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    25441 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    25501 gtcctttcag ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact
    25561 ttctttatca gtcagtcagg tgactttatc aaaacgcagg aatttagtca tgctccgggg
    25621 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    25681 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    25741 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    25801 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    25861 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa
    25921 gtggaagaaa aattggttta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    25981 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    26041 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    26101 ttgggtaact acgatgtcaa gagcacgcta ccaggagaag ttgtcaagga cgttgccttt
    26161 tatgactacg atgccaagta tattgataac aagattacta tggatattcc tgccaaaatc
    26221 agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt
    26281 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    26341 gagctcaata ccatgccagg tttcacccag tggtctatgt acccactact ttgggacaat
    26401 atggggatca gctacccaaa actaatcgag cgtttggttg accttgccaa ggaaagtttt
    26461 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    26521 tgcaaggtga ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa
    26581 caatccatga aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca
    26641 cccagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc
    26701 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    26761 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt
    26821 tgacatcctt tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    26881 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    26941 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    27001 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    27061 tgggcgatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    27121 ttggagaagc ccatttggcc tttttcaaag accgttcaga gattgctaag ggaaaaatgc
    27181 aaattgcaga cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag
    27241 aggactattt gccaactgat aaaaaggtgg tccgttttgg gcaaggggca gagttggaaa
    27301 tcacagactt ggttgagcgt aaggacagtc tgacctttaa ggccaatttc ttagagcaag
    27361 cccttgattt gccagtaact ggtaagtaca atgctaccaa tgctatgatt gcgtcctatg
    27421 ttgccctaca agaaggagtt tcagaggagc aaattcatca ggccttccaa ggtcttgaat
    27481 tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg agcagatatc ctgtcagacg
    27541 tatataatgc caatccaact gctatgaagc tgattttaga gactttctct gccattccag
    27601 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    27661 ctattcaact ccataaccag atgattttga gcctttctcc agatgtgctt gataccgtta
    27721 ttttctatgg agaagacatt gctgaattag cccaattggc cagtcaaatg ttcccaattg
    27781 gccacgttta ctacttcaag aaaacagaag accaagacca atttgaagac ctagttaagc
    27841 aggtcaaaga aagccttggg gctcatgacc aaatcctgct caaaggctct aactctatga
    27901 atctagccaa gttggtagaa agtttagaaa atgaagacaa gtgattttgt caagtatttg
    27961 caaagaatga ttgccattac agatactgga ttaaccttta caaaagatcc gtttgaccgt
    28021 gagcgctacg aagacttgcg agaccttcta tctgaaatgt tgaatcaagc atcagacctt
    28081 gattccgaag aagtggcaga agtcttgaag ccaacttctg cttatgcgac tcccttaatg
    28141 gacgtccgtg cttggattgt tgaggacgaa aagatttgtc tggttagggg acaaggagag
    28201 gatagttggg ctttgccagg tggctttggt gaagtcggct attctccaac tgaaaatatt
    28261 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt
    28321 tttgatacca atcgtttcca actacagagc aaacaatatg caaagtttgt ttttgaatgt
    28381 aagcttctcg atggacaatt ccaagaaaat caagaaatcg ctgaccttca attttttgca
    28441 attgacccac tgccgaattt atctgaaaaa cgcattacca aggagcaaat cgagattctt
    28501 tggcaggttt atcaaggtca gagggagcaa tatcttgact aagaagatga ttatcgtatt
    28561 tctaaatcca tttttgacaa ctagcatggt ataataatat gcaggaaaat tttgaattat
    28621 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    28681 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    28741 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
    28801 cagttaatcc ttctttatgg ttggtactgg gttaatcata tgccactgtc agaaagccta
    28861 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa
    28921 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    28981 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    29041 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    29101 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
    29161 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    29221 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    29281 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    29341 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    29401 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    29461 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    29521 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    29581 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    29641 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    29701 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    29761 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    29821 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    29881 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    29941 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    30001 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    30061 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    30121 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
    30181 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    30241 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    30301 gcaaattagc ggaaggctta aaactgaatt acggggaagc ctatccgcct cttgcaagca
    30361 aagaaacctt ccaagtagag gttattggag aagtagaagc agtcgaagtg acggaagcct
    30421 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    30481 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    30541 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    30601 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    30661 ttgcgggtca attaacagaa gttaatcttt tggctcaagg agcgataaaa ggtgagaatg
    30721 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
    30781 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    30841 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    30901 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    30961 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    31021 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    31081 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    31141 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    31201 agcgaagaaa cattgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    31261 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
    31321 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    31381 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    31441 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    31501 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    31561 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    31621 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    31681 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    31741 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    31801 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    31861 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    31921 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    31981 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
    32041 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    32101 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    32161 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    32221 agaaaataca gaacttgttt ttcgagaagt tggagaggct agtctgagtg ctcatcgaga
    32281 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    32341 cttgctttcg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    32401 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    32461 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
    32521 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    32581 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    32641 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    32701 tagcagtgag cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca
    32761 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
    32821 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    32881 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    32941 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc
    33001 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
    33061 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    33121 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    33181 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    33241 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    33301 aaaggtagct tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga
    33361 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    33421 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    33481 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    33541 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    33601 atagcgggtc ttgatttatc tgtttgggtt gcgattgttt tggttcgatt tttaggagaa
    33661 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    33721 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    33781 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    33841 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtatcgagt gagtatgttc
    33901 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    33961 aggaaattgt gtattccaat aaatttgaat atttaacgca tgctaagatt ttagggacag
    34021 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    34081 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    34141 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    34201 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    34261 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    34321 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    34381 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    34441 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    34501 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    34561 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    34621 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    34681 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    34741 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    34801 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    34861 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    34921 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    34981 agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    35041 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    35101 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    35161 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    35221 agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg
    35281 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccggg atttgaagca
    35341 ccgcaagaat ctgttacaat tttataagaa atattctgag aacaatatct tatccttata
    35401 ttcccagcga gcaggagatg gtgtgagtcc tgcattccct atcgataaga ttatcctctc
    35461 aaaaactcaa gtctgaatct agtaagattt gacgttcccc acgttacggg ataagaggga
    35521 gaaagactaa aactttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    35581 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactcaa agacaccctt
    35641 aatcttggga aaactgaatt cccaatgcgt gcaggccttc ctaccaaaga gccagtttgg
    35701 caaaaggaat gggaagatgc aaaactttat caacgtcgtc aagaattgaa ccaaggaaaa
    35761 cctcatttca ccttgcatga tggccctcca tacgctaacg gaaatatcca cgttggacat
    35821 gctatgaaca agatttcaaa agatatcatt gttcgttcta agtctatgtc aggattttac
    35881 gcaccattta ttcctggttg ggatactcat ggtctgccaa tcgagcaagt cttgtcaaaa
    35941 caaggtgtca aacgtaaaga aatggacttg gttgagtact tgaaactttg ccgtgagtac
    36001 gctctttctc aagtagataa acaacgtgaa gattttaaac gtttgggtgt ttctggtgac
    36061 tgggaaaatc catatgtgac cttgactcct gactatgaag cagctcaaat tcgtgtattt
    36121 ggtgagatgg ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcatgg
    36181 tcatctgagt cagcacttgc tgaagcagag attgaatacc atgacttggt ttcaacttcc
    36241 ctttactatg ccaacaaggt aaaagatggc aaaggagttc tagatacaga tacttatatc
    36301 gttgtctgga caacgactcc atttaccatc acagcttctc gtggtttgac ggttggtgca
    36361 gatattgatt acgttttggt tcaacctgct ggtgaagctc gtaagtttgt cgttgctgct
    36421 gaattattga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt tttggaaact
    36481 taccgtggcc aagaactcaa ccacatcgta acagaacacc catgggatac agctgtagaa
    36541 gagttggtaa ttcttggtga ccacgttacg actgactctg gtacaggtat tgtccataca
    36601 gcccctggtt ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca
    36661 gtgactgttg atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa
    36721 ttctatgaaa aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa
    36781 gaagaaatct ctcactcata tccatttgac tggcgtacta agaaaccaat catctggcgt
    36841 gcagttccac aatggtttgc ctcagtttct aaattccgtc aagaaatctt ggacgaaatt
    36901 gaaaaagtga aattccactc agaatggggt aaagtccgtc tttacaatat gatccgtgac
    36961 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc tatcttctac
    37021 gctgaagatg gtacagctat catggtagct gaaactattg aacacgtagc tcaacttttt
    37081 gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga
    37141 tttactcatc caggttcacc aaacggcgag ttcaaaaaag aaactgatat catggacgtt
    37201 tggtttgact caggttcatc atggaatgga gtggtggtaa accgtcctga attgatttac
    37261 ccagccgacc tttacctaga aggttctgac caataccgtg gttggtttaa ctcatcactt
    37321 atcacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    37381 gcccttgatg gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc
    37441 gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca
    37501 agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac ttaccgtaag
    37561 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    37621 acagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg ctttaaccag
    37681 cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat ctacaaggcc
    37741 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    37801 gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt cttctatgac
    37861 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatt
    37921 tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagagtt accagaggct
    37981 caaacttttg ctaatcaaga agaaatcttg gatacatggg cagccttcat ggacttccgt
    38041 ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt
    38101 gaagcacact tgacagttta tccaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    38161 agcaatgtag ctcaactttt gatcgtgtct gagttgacca tcgtagaagg accagctccg
    38221 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgtgctac tggtgaagta
    38281 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc
    38341 tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    38401 gaagagaaat aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa
    38461 ttttatagtc tattaaacgc attgtatcac gtttttgaat acctgatatg atgcgttttt
    38521 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    38581 cttagcaatc taacagtagt aagataaaat aggaatttga tattagggat aagattggta
    38641 aatagtgtaa tatttttaca acaataaatt tatatagtta tttctggttt ctgaaaa
//
LOCUS       DBEJJE010000018        35056 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEJJE010000018 DBEJJE010000000
VERSION     DBEJJE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.18"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(145..1341)
                     /gene="pgk"
                     /locus_tag="ACL3F5_000905"
     CDS             complement(145..1341)
                     /gene="pgk"
                     /locus_tag="ACL3F5_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0514737.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(1431..6341)
                     /locus_tag="ACL3F5_000906"
     CDS             complement(1431..6341)
                     /locus_tag="ACL3F5_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0514738.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKSRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEEAHVFEIEGLDEKGQDVDPSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            6634..8265
                     /locus_tag="ACL3F5_000907"
     CDS             6634..8265
                     /locus_tag="ACL3F5_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR0514739.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(8824..10431)
                     /locus_tag="ACL3F5_000908"
     CDS             complement(8824..10431)
                     /locus_tag="ACL3F5_000908"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0514740.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(10821..11408)
                     /gene="rpoE"
                     /locus_tag="ACL3F5_000909"
     CDS             complement(10821..11408)
                     /gene="rpoE"
                     /locus_tag="ACL3F5_000909"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0514741.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(11536..11847)
                     /locus_tag="ACL3F5_000910"
                     /pseudo
     CDS             complement(11536..11847)
                     /locus_tag="ACL3F5_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
     gene            complement(11745..12161)
                     /locus_tag="ACL3F5_000911"
     CDS             complement(11745..12161)
                     /locus_tag="ACL3F5_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514742.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            complement(12189..12839)
                     /locus_tag="ACL3F5_000912"
     CDS             complement(12189..12839)
                     /locus_tag="ACL3F5_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0514743.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(12829..13392)
                     /locus_tag="ACL3F5_000913"
     CDS             complement(12829..13392)
                     /locus_tag="ACL3F5_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0514744.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(13557..13791)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13845..14348)
                     /locus_tag="ACL3F5_000914"
     CDS             complement(13845..14348)
                     /locus_tag="ACL3F5_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0514745.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(14541..15371)
                     /locus_tag="ACL3F5_000915"
     CDS             complement(14541..15371)
                     /locus_tag="ACL3F5_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0514746.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(15356..17038)
                     /locus_tag="ACL3F5_000916"
     CDS             complement(15356..17038)
                     /locus_tag="ACL3F5_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514747.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DIVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(17140..17397)
                     /locus_tag="ACL3F5_000917"
     CDS             complement(17140..17397)
                     /locus_tag="ACL3F5_000917"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514748.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(17404..17952)
                     /locus_tag="ACL3F5_000918"
     CDS             complement(17404..17952)
                     /locus_tag="ACL3F5_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0514749.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(17967..18815)
                     /locus_tag="ACL3F5_000919"
     CDS             complement(17967..18815)
                     /locus_tag="ACL3F5_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0514750.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            19004..20353
                     /gene="trkA"
                     /locus_tag="ACL3F5_000920"
     CDS             19004..20353
                     /gene="trkA"
                     /locus_tag="ACL3F5_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0514751.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            20357..21796
                     /locus_tag="ACL3F5_000921"
     CDS             20357..21796
                     /locus_tag="ACL3F5_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0514752.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(21921..22322)
                     /locus_tag="ACL3F5_000922"
                     /pseudo
     CDS             complement(21921..22322)
                     /locus_tag="ACL3F5_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            23372..23656
                     /locus_tag="ACL3F5_000923"
     CDS             23372..23656
                     /locus_tag="ACL3F5_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514753.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23649..23897
                     /locus_tag="ACL3F5_000924"
     CDS             23649..23897
                     /locus_tag="ACL3F5_000924"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514754.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            23993..24211
                     /locus_tag="ACL3F5_000925"
     CDS             23993..24211
                     /locus_tag="ACL3F5_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514755.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMEFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(24579..26903)
                     /gene="pflB"
                     /locus_tag="ACL3F5_000926"
     CDS             complement(24579..26903)
                     /gene="pflB"
                     /locus_tag="ACL3F5_000926"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0514756.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            27251..28312
                     /gene="dinB"
                     /locus_tag="ACL3F5_000927"
     CDS             27251..28312
                     /gene="dinB"
                     /locus_tag="ACL3F5_000927"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0514757.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKGKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(28459..29304)
                     /locus_tag="ACL3F5_000928"
     CDS             complement(28459..29304)
                     /locus_tag="ACL3F5_000928"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0514758.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            29559..30347
                     /locus_tag="ACL3F5_000929"
                     /pseudo
     CDS             29559..30347
                     /locus_tag="ACL3F5_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(30729..32618)
                     /locus_tag="ACL3F5_000930"
     CDS             complement(30729..32618)
                     /locus_tag="ACL3F5_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0514759.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            32756..34321
                     /locus_tag="ACL3F5_000931"
     CDS             32756..34321
                     /locus_tag="ACL3F5_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0514760.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            34321..>35056
                     /locus_tag="ACL3F5_000932"
     CDS             34321..>35056
                     /locus_tag="ACL3F5_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0514761.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
BASE COUNT        10395 a         7630 c         6521 g        10510 t
ORIGIN      
        1 tcaaaaaacg gatttttatc gccctgaata tcaaaaaaga aaggacgaaa tttgtccttt
       61 ctcaagctta gctttttttc aacccactac agttgacaaa gagccaactt tcatccctct
      121 cttctttgat ttgtttataa aatcttattt ttctgtcaag gctgcaagtc ctggaagaac
      181 cttaccttca agaagttcca ttgatgctcc accacccgta ctaatccatg agaacttgtc
      241 tgcacggcca aggttaatcg ctgcggcagc tgagtcacca ccaccgatga ttgatttaac
      301 tcctggttgt ttcacgatag cgtccatcac accgattgta ccagcttgga aatctgggtt
      361 ttcaaataca cccataggtc cgttccatac aactgttttg gcaccagtca aagcttcgtc
      421 aaatttggcg atagattttg gaccgatgtc aagaccaagg aagccttcag aaactgcttc
      481 accttcagtg tcacgcactt cagtgtaacc agcaaatgcg ttagcttctt ttgagtcaac
      541 tggcaagatc aatttaccat ttgctttttc aagaagagct ttcgcaacat ccaatttgtc
      601 ttcttctaca agtgagttac cgatttcgat accttgtgct ttgtagaatg tgtaagtcat
      661 cccaccaccg ataaggactt tatcagcttt ttcaagcaag ttttcgataa caccgatctt
      721 gtctgaaact tttgaaccac caaggatagc cacgaatgga cgttctggag tttcaactgc
      781 ttcttggatg taggcaattt cgttttcaag aaggaaacca gcaactgctt tttcaacgtt
      841 tgctgagata ccaacgttag atgcgtgtgc acggtgagct gtaccgaatg catcgtttac
      901 gaagatacca tctccaagtg atgcccagta tttaccaagt tcaggatcgt ttttagattc
      961 tttcttgccg tcaacatctt cgtaacgagt gttttcaacc aagagaactt gtccatcttc
     1021 aagagcgttg attgccgctt ccaattcagc accacgagtg acacctggga aaacaacatc
     1081 ttgaccaagt tttgctgcca agtcagctgc tacaggagca agtgatttac cagctttatc
     1141 agcttcttct ttcacacgtc caaggtgaga gaaaagaatt gcacgtccac cttgttcgat
     1201 gatgtactta atagttggaa gagctgctgt gatacggtta tcgttagtga ttacgccatc
     1261 tttcaatggt acgttgaagt caacacgaac gaggactttt ttacctttca agtcaacgtc
     1321 tttaacagta agttttgcca tgttacaaaa actcctttat ttattttatt cgaaactatt
     1381 atatcacact ttggaaatat aaggaaagat ttcacaagat ttttcgatat ttaatcttta
     1441 tcttctcttt tccgtctcaa ggtcaaggct aaactagcaa gaccaaggct ggctaagcct
     1501 gctattaggg cttcattagc atcagctgtt cctgtatttg gcaattgttt gcttgcttct
     1561 tctgatttaa ctgctgtatt ttgagctggt ttttcctgtg tagctactac tgctggtact
     1621 gtttttactt ttgttccaat ttcaacaatt tctggaatcg cttcttggat gacttctgtt
     1681 gaacgaagac gacgctgacc gttttcatca acttcaaaga catgtcttaa cagtccatct
     1741 cgtccctgta tgatgactcg ttgttcccca actagcatct cagcattttc atgctcttga
     1801 cgatgaaagg caaccttttc ctcttgaact tccaatttag gagccttttg ttgatcagaa
     1861 gccggttgat aagtaggttt tggaaggact gtgttttgtg gtgctggttt agcaggttgt
     1921 ggtttttcag cagattcata aacaaaggca taatgagtaa agtgaggtgc tgtaaagata
     1981 acatgactat ccgtttgttc aaaagccaat tctactgcct ctttgccttc aggtaagaaa
     2041 aatactttct taactttctt atctttttca attgggattt tcacaataga agcataagag
     2101 ggatcaacat cttgaccttt ttcatccaaa ccttctattt caaagacatg agcctcttct
     2161 ccagcaaagt atttcttctc ttcagcactt gcttgaacac gctctacttt caaacccttg
     2221 atgacagtct tctctttatt tgagaagtgt acttcaacac ctgttttact atcagaaaag
     2281 actgctgact tgtcttcttt caataaagca accagatctt ttagactctg tttcgctgtt
     2341 gcaagctctt ctggactcaa atctactttt tcaaccaagg ccttgttttt ctcaagaagc
     2401 ggagctaggg cagaacctga aggatggttt ggtttggcag ccaagagttc ttgagcctca
     2461 cctgttaagc gatcaagctc tgtcttttct tccgtaaatt tctcttgacc attcagagct
     2521 ttatgagctt ctgtcaattt attaagtcgg tcattgactt gatcttgggt gctagtttca
     2581 tggtctttca acacttgttc ggccgcttca attgctttca agaaggcttc ttttacttct
     2641 ggtgaagcaa agttatagac caccttgttc ttagcagctt caacttctgc taatttttgt
     2701 ttgaggtact catcgttcaa tgctgctttt ggagatacca aaacatcaaa gttgacttca
     2761 tgaccttggt aacgaagcgt caaggtttga cgaccagtct tttgagcatc gtaaccagaa
     2821 atttcaactc cctcatcagt aaaggaatgt tcttccatgg tgtcattgct ataagccact
     2881 gcaaagcgtc cttcagacaa gtctaagcta tcaccaacta ggtaatcttt tttcggttcc
     2941 tgacttactt caattcccaa aatagttttc ggacttgctt catcttggcc agtgacagtc
     3001 actgacaaat tagcatttac tggttgtccc aaatattgga gagtaagatt ctgttctccc
     3061 ttatgatgcg tatcaaaacc tgatactgat acacctgcgt gagttaggcg aatgagttcg
     3121 tcctcagttc ctccttcata ctgaactcga agaacaccac ctctaaggtc caaatcctcc
     3181 ccttcggcgt agcttgtttt cttaggtcct gtttctaggc tgactgactt gattcttctg
     3241 tcatcttttg gaacggaaac tgctaggaca ttactaattt ccttgcctgg caactgggta
     3301 cgataataaa gaagaccaga ttgatttgtc aaatccaatg gtgcacttgc taggtctcct
     3361 ccaacttcgc tcttcaaggt tgcgagcgga gtttgagaat ttggattatc ataaacggta
     3421 atagttgctc cagccggtac atctgcaaag ccaacttgta ccttgttatt gcctagagaa
     3481 cgggctgcag ccttggccat cggaatattg acactctcag tatcaagctt ttcatacatt
     3541 ttccagttat agatacgaat agccttccat ggagttccat tgtcagaagt gacaacattc
     3601 aagcgccagt cctgagcagt gattggttta tcaagagtga tatctgtcac gtgtgctttg
     3661 ttaccacgga cttccttagc tagcttccac tcaccatctg catctttata ataaaggtca
     3721 aagtctttag tgttcatcaa gccatcgtta acagactcac caccagctcc tgcatgatcc
     3781 atgacccatc taacaacggt acgtgacttg gtcaaacgaa tatccacact accactcaac
     3841 tgagctgaag accatttatc tgacaagcta gtaatggtac cgttcaacat accttcaata
     3901 ccttctccac cttcagtctt agggaaagta ctatcaataa ctgttgcacc tggaacgata
     3961 ttttcagcta gtggttttgg taggctggta tcttttacag tcatacccca atcaaaggtt
     4021 gtggttgcag cttctgaacg aactccattt ttaccgactg ctacaacctt cagttcttga
     4081 gttgtaccct gagcacttgc tgagcggcta acttttggta gataaatagt tgtagaagat
     4141 gagccagtta gtaatttcca gctgtctcca tctttttcat aaacttcata gaaatctgca
     4201 tccttgttgc ctttaaattg cacaactgct tccgcttctt gggcattttt aagagattgt
     4261 ttcactacag aaaagcttgt cggcgattgt ggctcttggt gattgtccga gatagttaat
     4321 tgtcctaggt tgaactgata atcttttaca gcaccttcat gctcgaaaaa tagtttgact
     4381 gcatagatgg ttttacctgc tagtgagctg agatcaaatt cttcatttgt ccagttgtca
     4441 gaaagggtta gctctttcca tgcatctgca tcatcgaatt tgtagtctgg agttgtagag
     4501 aatgccatat aaactttaga accttttcct cccttgtggg caacacgaag tttggtcttc
     4561 tcagttactt ctaacttagt agaataaagt ctcacatcct gatctgtctt accggctaca
     4621 tcaccagaga atttaaggga atttccgcca ttataggcat ctgtaaaatc atattctgca
     4681 cgaagttttt cccctgttga agtctgccac cagcgccatg ttggaagaac acctgatact
     4741 gaacgataat tccactcaga atccttagaa accttaccat ctacgaacca ttttttacca
     4801 tgacctgtat taaaagaagt agtaaaagta ttacctaccg ctggcgtacg gtccgcaact
     4861 aggttagcaa taccatacca atctttgtca cctggttttt ggccagtagg gtctccttga
     4921 taacctgtaa agaagatatc ttcattttta tgataatctt caccagtttt tcctaaactt
     4981 gtaatggtat ctggggcaaa taaaccaaga gaaaggcgca atttcccatt ttcgtctaaa
     5041 atgtcattcc acttaacctt tgtcttgtag gaaccaccct gttgcaattc caaacctgca
     5101 aatacatcat aaggattacg accaatccag ttggcagttg caatagtgta atcattttta
     5161 gccttatccc agttaaagtt agcaaagaag ttatctgccg gaaccttatc tccttctggt
     5221 tgcatgaatt ggtagttgta ttctcccaaa ccatcttgat ggtaacgtcc atagttatag
     5281 gtcatggcat cataccaaga atacttgatt ggatggttta ccttagcagc atattccttg
     5341 ctatagagca taaactggcg catcttttct ccaagaggtt taaccaaatc tccagttgtt
     5401 tcttggttga tgaaatagcc atcatagcca taatacttgg ccatgtctac caatttacgg
     5461 gcaattggga agctaccatc tgcgtcttgc ttcaaagctt cagcaaatct ttcttgatct
     5521 gcaatactat tagaccagtt gaagaagagt gtaccgtata caggaacccc gttacggtga
     5581 cctgcatcaa taacgtcagg agttggtacg agaccttccc agaagaccat tgaatctaga
     5641 tattgccaat agtcaaaagc ataggccttg aactcttctc caccaacaga agcatggtct
     5701 tttgctttag aattggtgtt tgataaggct tgaacttttg cttccttgct agctttttca
     5761 ttgactaaat gacctgtccg acgtgaagcg aggacaacag atccgcggtt aatagcatca
     5821 tcttcacgag cacctggttc ccattttaac aattcttccc aagaattaaa tttgatttcc
     5881 tttggtttta atgttttttc tgtattttta gggacatctg gctggacttc tttttcagtc
     5941 ttattagctt ctgctgctgg cttagactca tccccttggt tagttgcttc gggctttgct
     6001 tctgtttcct tgtcagactt aggttttgct tctgcagatg gtgtttctgc aaccacctca
     6061 cctgcttttt cctctggttt agctgcgcta gctgcttctg ccttttctag cttgttttct
     6121 ctagcatgtt ccccttcatt ctgcttatca gcttcattgg tcgaatgctc actctctcct
     6181 gaaacaagct ctgtattagc tccgctattt tcaggaactg cagtttcttc agccaaggct
     6241 ggaccagcaa ataaaacagc accaatcatc agcgagcagg ctcctactga taacttacga
     6301 atactgtaac gacaacgtct ttcaaaaaat ggattcttca ttttctcctc ctaaaagatt
     6361 gattttgttg ttttaaagaa agcgctttat attctgtagt tttttatcaa actctagaac
     6421 catgataatc acatttttat cctaaaacat ttttagacaa aaaacaataa ctgtttgcac
     6481 aaatctaaaa taaggttaaa aactcttaaa aataatacac ttatcaatta taattttctt
     6541 ttacaaactt gacattaaca cttgttagat ttacttttat cctttaaaat agaataggag
     6601 atattccgcg attatttttc ggaggaaaaa gaaatgtcca ttaattggca ggaaatttta
     6661 tttcactttt taggtggtct ggggctattc ttatatagca tcaagaccat gggagacggt
     6721 ttgcaacaag ctgctggaga tcgccttcgt ttttacattg acaaatatac tagtaatcct
     6781 ttctttggag ttctggttgg tattgggatg actgctctaa ttcagtctag ttctggtgta
     6841 acagttatta cagtcggcct ggtcagtgcc ggtctcttaa ccttacgtca ggctatcggg
     6901 attgtcatgg gtgctaatat tgggacaact gtcacatcct ttctcatcgg ttttaaatta
     6961 ggtaactatg ccctacctat gctctttatc ggtgccgtct gtctcttttt tacgaaaaat
     7021 cggacagtca ataatatcgg acgcatcctc tttggtgtcg gtggtatctt ttttgccctc
     7081 aatctcatga gcggcgcaat ggctccactc aaggatttac aggtctttaa ggactatatg
     7141 attgagctaa gtaagaatcc tgttttgggt gtctttgtcg gtaccggctt gaccttgcta
     7201 attcaagctt cttcggctac cattgggatt ttacaaaacc tctacgccgg caatctaatt
     7261 gacctacagg gagctttgcc agttctattt ggtgacaata tcgggacaac cattacagcc
     7321 atcattgcct ctttaggggc taatattgca gctaaacggg tagcaggagc tcatgttgcc
     7381 ttcaacgtta tcggaacagt cgtctgcgtt atttttctag ttccttttac tgtcctgatt
     7441 cattggtttg aagctacgct aaatctagca ccggaaatga ccatcgcctt tgctcacgga
     7501 acctttaata ttaccaacac cattgtccaa tttccattta tcggagctct ggcttacttt
     7561 gtaaccaaga ttattcctgg agaggacgag gttgtcaaat acgaaccctt atatcttgat
     7621 gaacatttca tcaaacaagc cccatctatc gctctaggaa atgctaaaaa agagctcttg
     7681 cacttaggaa actacgctgc taaagccttt gacctttcct ataagtacat cattgacttg
     7741 gatgaaaaag ttgctgaaaa agggcataaa accgaagaag caattaacac catcgatgag
     7801 caattaacac gttatctcat tgccctttca agcgaagctc tcagccaaaa agaaagtgaa
     7861 gtgctcacca atatccttga ttcctcccgt gatttggaac ggattggaga ccacacggag
     7921 gctctactca atctgactga ctatcttcaa cggaaaaatg ttgaattttc tgatgccgcc
     7981 ttgaaagaat tagaggaagt ttaccgccaa actagtgact ttatcaaaga tgctctggat
     8041 agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg tagaacgtca tgaagcaatc
     8101 aataagatag aacgtgttct cagaaaaacc cacatcaaac gcctcaacaa aggcgaatgt
     8161 tcaacacaag ctggggtcaa ctttatcgac atcatctcac actacactcg tgtatcagac
     8221 cacgctatga accttgctga aaaggttttt gcagaacaaa tctaagaacc aagaagctat
     8281 ccatcataat tggatggctt cttacttttt cctaagcaag actaggctga atgaaactga
     8341 aagagtattc tgcagatata tagtatattg aaactagaat agtacacctc tatttctaaa
     8401 acattgttag aaatcgattt gactgttctg atcgatttgt cctgttatta tttcatttta
     8461 ctatagtgga ttaaattaaa aaagtataat gtattgaatc tataacagta catcttgact
     8521 gctaaaatat ttctataaat taatttgact ttccttatag agatgttcac atcttatttc
     8581 aattcatgat acaatccagt tcctaaaact ttgctagaaa ttaatttggc tttccgaatt
     8641 aatttgttca gattttattt catttcaata tactgataaa tccattcact agcacagggc
     8701 aagagggagt cgctattgat ttcaacggta gcaggtacat acagaggact cctacctcag
     8761 atatactgca atatcatcgt atgcaaaaaa cctctgagat ttttctcaaa ggttctgatt
     8821 ttgctaattg ctgttctcaa ccgctgcagt aacaaaggca gtgtagagtt cttctggtcg
     8881 gtttggacgg cttgacagtt cagggtgata ctgacaagct acaaagaatt tattttcagg
     8941 aatttccacg atttctacca aacgattgtc tggagaaact cctgaaaaga caaaacctgc
     9001 tgcctcaaac tgctcacgga aggcattatt aaactcataa cggtgacggt gacggcgttg
     9061 caccacttct tgattgtgat aagcagcagc agccttagag ccacgtttca acttagacgg
     9121 ataaagtccc aaacgaaggg ttccacccat atcctcaata tcaatctgat cacgcatgat
     9181 atcaatgata gggtattttg tttctggtgc aagctctgca gaattggcac cttcaagacc
     9241 taaaacgtga cgagcaaact cgatacatgt caactgcatt cccaagcaga ctcccaacat
     9301 tggaacatca ttttcacgcg catagcggat ggcttggatt ttcccttctg taccacgttg
     9361 accaaaacca cctggtacga tgatcccgtc cgcatcagac aagagttctg ctacattctc
     9421 tgctgtcaca tcattggcat tgacccaatt gattttaact tctgcatcat tgacatagcc
     9481 agagtgtttc aaggcttcga ccactgagat ataggcatct tgcaactcca catacttacc
     9541 aacaagggaa atcttaactt gtttcttgag gttcatgacc ttgtccacca tggctgacca
     9601 ttctgtcata gccgctgctg gtgcgtctaa tttcaaatga tcacaaacaa tttggtccat
     9661 cccttgtgcc tgcaagttca gtggaatttg gtaaaggtgt tcaacatcca acgattcgat
     9721 aacggcttct ggtgccacat cacagaactg ggccagttta tttttaattc cttgaccagc
     9781 tggctcttct gtacgaataa ccaacatatt tggttggatt cccaagccac gcaattcttt
     9841 gacagagtgt tgggttggtt tggttttcat ttcaccagca gccttgaggt aaggaagcaa
     9901 ggttgtatgg atatacatga cattatccgc acccacatct gccttcatct gacgaagagc
     9961 ctctaggaat ggcaaggact ctatatctcc tactgttcca ccaacctctg tgataatgac
    10021 atcagagtcg gtcgttagag cggcacgctt gattttttct ttcaaagcat ctgtgatatg
    10081 aggaatgact tgaacagttg ccccaaggta ttctccacgg cgttctttac gaagaacttc
    10141 actgtaaatt ttcccagttg tcacgttgga atatttgttg agattgatat cgatgaaacg
    10201 ttcatagtga cccaagtcca aatctgtctc agctccgtca tctgtcacaa aaacttcccc
    10261 gtgctggtaa ggactcatgg ttcccggatc aatattgata taagggtcaa acttttgaat
    10321 ggttactttg agaccacgat ttttcaagag acggcctaga ctcgctgcca caatcccttt
    10381 cccaatagac gataccacac caccagttac aaaaatatat ttcgtagaca tagattcctc
    10441 tttctaaaat gctcaaggtc ttgttaacta cgaggggata tagaaaacaa gaccctacta
    10501 ataagaataa tctgggacga ctgcaccaga ttcacaacta atactcttcg aaaatctctt
    10561 caaaccgcgt caacgtcgcc ttgccgtaga tatgtgttcc tgactttgtc agtcttatct
    10621 acaacctcaa aacagtgttt tgagcagcct acggctagtt tcctagcttg ctctttgatt
    10681 ttcattgagt ataaaataca agaagataac ttcttgaaaa aacaaaaata gctccctaag
    10741 aactagggag ccccgacctc taaaagaggt gcccaaacaa tatgatacct aaaaatagga
    10801 taattgtcaa tagctaactc ttattcctcg ctggtttcag cgtcgtcatc tgaaaactcg
    10861 tcgtcgtctt cgttgagatc cacatcttct cccaagtcat ctggagcgat ttcgttgatt
    10921 tctgcatcat aagcttccac ttcatttttt tcatcatctg gattttcatc atcgtatgaa
    10981 agagctggat ctgcttcgta tgcatcttcg tcttctggat catctgcatt gtagtcaatg
    11041 gcatctgaat caccatccat aaaggcattg acacgttttt tcttagcttt tggtgctact
    11101 tcatcgtcgt cattttcttc aagagcgatg atttcttcgt cgatttcgtc cacaccatac
    11161 catgaacgaa gaccccattt gttgtcccca agtgagatga agctaccgtc aaagttcaac
    11221 tctgtgtaga acaaaggcaa agcttcgcgg atatcgctgt ttgatgttcc aaggtagttt
    11281 tgaatttcgt ttacaagatc gctaaaatgc atctcatgat cgcgaccacg aagttctaag
    11341 atagcacgcg ctacctcaat catagatagt tcactttttt cttgcccagc aaatacttct
    11401 aattccaaag cgtttctcct catttatact actatcgtca gagcgaacag actctgacct
    11461 cattttatca tttactcttt attttacgat aattttgcgg aatagtcaaa ggttaagggg
    11521 gagaaagtgg caggattaga ctaattccaa tataaaactc cttccttttt ctgttgctcc
    11581 attttccaca aatccaagcg acttgaaaca cctcctagaa gcatgattgt aggtgtagat
    11641 ttccttgact ctcaattctt tccatccttt tactcgagcc aattcaatca aagcacttag
    11701 aatctttttt ccaagtcctc gatgttggta agcggaattc ccaatcacaa tggggagatt
    11761 atcctgagat agtgtaatat ccccaattgg aaaccattct cccttctcct tgacttcaat
    11821 ccaaaaaagc tcaccatgcc gatccaaaga ggtaagatat gattttttaa atcaaaaaca
    11881 gagtaaatct ttctttcctc gcaagcttgc gcatagagat gatatagttc atcaccacca
    11941 tctctatccc actcagcaga aatcgtatcc cgacctgcca ataaagcctg ataagccctg
    12001 tgatgcccat ctgtaatcag caaacaatct ccaaaggcaa gaatactgat tggatcgact
    12061 tggattgttt ctgccgactg gtaaagcatc tgaatatctt gcaacttctt ttctgataaa
    12121 tatagttgag tcggatgaag atctgctata ttgactttca tttctttctc ctcaagggaa
    12181 ttcgatactc acttctgttt gcctttaaat cgccattgga agcggagctt gtcatagaag
    12241 ggaaactcga taaacaaaac tcccaagccc acacagagac tggcaaggac gtctgatggg
    12301 taatgaactc ccagatagac tcttgatacc agcacactga ctaggtagag gccaaggacg
    12361 atttgtacga tttttctcca gacctgatct ttaatccgct gactaagaat aacaatcaaa
    12421 gtccctacca tcagcgttac agctagagaa tgcccacttg ggaaggaaaa tcccttctcc
    12481 tccaccagat gtaaaatagc tggtcgtggg cgctggtaga tatttttaaa ggtcacgatt
    12541 aaaagacctg ccaaagccag atttcccaac atgaagaaac tttctatctt ccatcgctta
    12601 cgataaaaga caaaagctgt aatgacaacc caagtgataa tcactgggat atcaatcaga
    12661 cgtgtgaggg ctcgaaaaag aatagtcaaa taatctggta agtctcctcg aatggcagtc
    12721 tgaatcgatt ggtcaaaatt gaccaacatt tcagggtaaa atttgaccat atagccaaga
    12781 ataacgaaaa gtaaaagggc aaaactgccc ttcattaaaa atgtttgttt atctttcata
    12841 gtgttttaag gttggtttca aaaggacgta caacaaccag aatgaaacgg aaaagattac
    12901 accctcaatc aagttaaaag gtaataccat ggtcattagg tagttggaaa gtcccaaaat
    12961 ttttccaata tcaaagttag caaacttagc gtacaaagga acagcataaa catagttgag
    13021 aaccaacatg gccaaggtta aaccaacagt tccagctaga gagcctagta ggaaacgaag
    13081 ggttgtccgt tcctttttcc aaatcaaagc aaatacgatg acaaaaactc ccaaagctac
    13141 gatattcatc ggcaaaccaa tgtaagtatt cactccttgg ctgttaagaa gcaatttcaa
    13201 tagtgagcga agcaagagca ctcctagagc agcaggcaaa tccatgacca ccagacccac
    13261 aaggactggc aagatactaa attcgatctt gaggaaagat gccgctggta aaagcggaaa
    13321 gtcaaagtac atcagcacaa atgagatggc tgatagaatt gcaatggtcg aaagtcgacg
    13381 tgtgtttgtc ataacaggtt cctccaattt tctataaaat cagaagaagt tggaaaggat
    13441 tcctctatct attctcactt tttatatccc aaaagttccc tcttactcta ttaaagaaaa
    13501 acaaagcaag tggttacaat ccggctataa atctatcaaa acagacaaag ctattctttc
    13561 gtcttctccc atccagacta tactgtcggt tgtggaatct caccacatca gcttgcgctc
    13621 gcggacttct ttaaagagaa ggaaatagag atttttcttt tagactaggc gacaagctgt
    13681 aggcataact tctggttagg caaagcttgt caacaaagta taaaaggaaa agatcatttc
    13741 ctagttaaag tcaccgccgg tcgggaatca caccctgccc tgaagactct tttatcataa
    13801 caaaaaacgc ttgcaagcgc aagcattttg ttcattttca ttttttattt caatttatcc
    13861 acttcatagg tatggacgag ctcaagacct gcaaagttct gctggcgaag agcctcatag
    13921 acaatcatgc agacggtatt agacacattg agactgcgga catgttcatc attcatggga
    13981 atacggagag ccttctcagg atgttctcgc ataaaatctt caggtaagcc cttgtcttca
    14041 cgtccaaaga gaaaataatg gtcctcgtca gtcgataaat ccacctcaga atagattttt
    14101 tccgcgaatt tcgaaatcag atagagtttt cccttcatct gagacatgaa atcttctaag
    14161 ctctcgtaaa aataaatctc tagcttatcc cagtaatcca atccagcccg cttcatcttg
    14221 cggtcatcaa taggaaagcc cataggcttg atgatgtgga ggggagaatt ggtcgcagcg
    14281 caagtacgcg cgatattgcc tgtattttgt ggaatttgag gttcaaataa tacaatgtga
    14341 tttgtcatga cttgcttcct ttcaccattg caaaaaaata gccacactgc ccggagtcaa
    14401 gctcagcaaa cagcgtggtt aaggcatcgt taacttacct cacaacaggt ttgaagtaaa
    14461 tcagcgaaac tactttctta gtataacact ttcagaatca ttgtcaatag aaatgacttg
    14521 attttttcaa ttttttcaag ctatttccaa gggttgtaaa atcgtccctg attctgcaag
    14581 ataagtagta aactaactac taaaaacaag gttgccaaga gcaaggtaat atagtctcct
    14641 tttttcaagg cctgataact ataccatgtg cgttttttct ctttcccaaa gcggcgaagc
    14701 tccatggcag tcgcaatggt atcaatgcgt tctagcgagc taaaaatcaa gggcgtaata
    14761 atgagcagat tgcctttgat tcgttgcata agagaagctt tcttggataa ttccatccca
    14821 cgcgcctcct gagacatctt gatagtaaag aattcttcct gcaaatctgg aatatagcgc
    14881 aaggtcaggc tgacagaata agcaatctta tagggcacac caatttgatt taaactggaa
    14941 gcaaactgac taggatgggt tgtcatcaaa aagataatag ccagaggaat ggtgcaaaga
    15001 tacttaatgg ccaaatttag cagataaaag agctcctggc tggttagagt gtagacaccg
    15061 attccctgcc aaatcacact tctctctcca taaagtccaa ccccatactc gggagaaaag
    15121 agatagacca tcaaaacgtt taaaacggca aataccgtcg caaaaacggc tacaaaggaa
    15181 acatctttaa agcgaatttc tgataaatag aggagaaaga ctgaaaagat ggcaatcagc
    15241 aagagcattc tggtatcata gctaatcatg gccgccaatg ataccagaat gaaaaagaga
    15301 agtttcccag ctcctgacaa gcgatgaatc acagtatctc tatgctggta accgattaat
    15361 ttagcttgca tccctctctc ctttctttgt aaaatgccgt taaatccagt ggatccacat
    15421 ctagtttctt agccaagtta aagatggagg tttcttttag attggctttt actaacagct
    15481 caggatcgct caacagactg gctggaacaa tatcggcaat caattctcca tccaccatga
    15541 caaggacccg gtctgaataa tccagcatca attgcatatc atgggtaatc atgacaatgg
    15601 tatgcccttt ttgatgtaac tcttcgagaa attccataat ctcagtatag ttcttctgat
    15661 cttgacctgc agtcggttca tctaggagaa taatttcagc tcctaagacc aaaattgaag
    15721 caatggtgac acgttttttc tgaccaaatg acagggcaga aataggccaa ttacggaatt
    15781 cataaagtcc acagattttc aaggtttcat agactctcgt ttcaatttcc ttctcatcca
    15841 cacctcgcaa acggagccct agagccacct catcaaaaat catattggtt gaaatcattt
    15901 gattaggatt ttgtagcaca tagcctactc gttccgcccg ctctgcaaca gaatcgcctt
    15961 ttatatcctg tttttcccaa agatagcgtc cttccgtctg aataaagcta cttatagcct
    16021 tggctagagt tgatttccct gctccatttt ttccgacaat agcaatcttt tcaccctttt
    16081 taatatctaa atgtagggat tttaaaatcg gtctatcatc ataagagaaa gacacgtcct
    16141 ctaatttaaa gagtgactgc aattctggag tttcttttgc cagttcattc tgcagctgaa
    16201 cctgaccttt tgagatagac atgttatcca gattcgctaa ctgttcttcc ttgactaagt
    16261 ccacacctaa ttgacggaga gtcgttagat aaaggggttc tcgaattcca ttttgagtca
    16321 ataaatcagt cgcaagcaac tggtcagggc tcccattaaa aaggatacga ccatcgttta
    16381 tcaagacaat ccgatccaca gggcgatgca gaacgtcctc caaacggtgc tcgataataa
    16441 gagtcgtcgt cccctcttcc ttatgaatct ggtcaatcaa ttcgataata tcctgacctg
    16501 acttgggatc tagattggcg agtggctcat caaacaagag aatcggactt tcatcaatca
    16561 agacaccagc cagactgact cgctgctttt gtccacctga caaatcctga ggacgctgat
    16621 ccagtaaagg aagaaggtcc agcttttcag cccatttata aacacgacct ttcatctcat
    16681 ctaaggctgt cacatcattt tccagagcaa acgccaaatc ttctgccaca gacaagccaa
    16741 taaactgccc atctgtatcc tgcaaaactg tgctaaccag atgagactta tcatagatgc
    16801 tcatatcaaa ggctgcttga ccctttatca aaaattctcc atatgtctga cccttgtaaa
    16861 tattgggaat aatcccattc aaacactgac ccaaggtaga tttacctgac ccagatggtc
    16921 caacaattaa gactttctct cccttgtaaa tggtcaagtc tatcccttgc aaggtcggtt
    16981 cttgttgtgt ttcataccgg aaagagaaat ccttccactc aattatagct tctttcatct
    17041 tactctcttc attcgcttct tagacttcta ttttatcata aatcaagccc ttcttgcagt
    17101 ctcttctctt aaaatcttag cgccaaaaag attcctatcc tagcttactt gcctaactaa
    17161 tctataaaca tcgaaaaaga ctagttgccc agccttcccc atcattttat actcttcgaa
    17221 aatctcttca aaccacgtca gcttcgcctt gccgtaggta tggttactga cttcgtcagt
    17281 ttcatctaca acctcaaaac catgttttga gctgacttcg tcagttctat ccacaacctc
    17341 aaaacactgt tttgagcaac ctgcggctaa cttcctagtc tgctctttga ttttcattga
    17401 gtattagtcc tttttcaaac ttcctgcacg agtttgggtt cctgcatagg caagtaagag
    17461 aagagttcct gcaatagcta cagatacacc attggcaatt cccgcaacaa tcccttgtgc
    17521 aaatactttt tctgctgctt cttgataaat cacaacatct ccaagtggtg ccaagacacc
    17581 ccaaacaagg gcatttgcaa gtagttgaat gagattaaaa ataagaatat ctttccagtc
    17641 aaaaacacta ttgatcacgc gaacgtactt tctaaaaagt cccacaacta aaccaaagag
    17701 tccgctagcg ataatccaag tccaccatag accataacca gcaagagagt ccttgattgc
    17761 atgaccaatt aacccgacaa gcaaaccgat aatcggtcca aaaataatag aaagtagcgc
    17821 ttgtaccgca tactgaagct ggatgcttgt atttggaaca ggggttggaa tgttgatcat
    17881 cccgatgacg acaaagaggg cagcgccaat tccgacagca acaacttgtt taattgtaaa
    17941 tttgatttcc atactattct cctattttat ccttctattt tctttatttc aatagtccaa
    18001 gatgaaccga cacctacatt ataggccttg gcaaaggaac cttggttgat agccaaacct
    18061 aaacgataga gagagttgat gtaaagaatg ggttgcccaa ttctcacatc tgcaaatgat
    18121 ttgccataga caacctgatt ttgatagacc agcatatcag catgatagat ggtcacttca
    18181 aaacgatcac caaattctgg ttccaacttg taaaattctt cccgtgtgat agaggtccaa
    18241 agcgaaccga aacgcacatc cagaatatca atggctccct tcaccagatg atcttctatg
    18301 atggtcgcta cgactggaag ctctacaatc tgttccacac tgagctctgg ccctacttcc
    18361 tcaaaagtaa tgtgaccact ggccagttta gcaccagtat aggcatagac atcacgaccg
    18421 tggaaggtat aagaatgctc tgtgttttga cgcctattgg ccacctcaga aatctcacga
    18481 atggctacaa tgccaacgtg tttcttgata aaggaaagcg tcccattatc tggcgtgaca
    18541 atgtattgat tttttgcagt cttggcaact acactcttac gtttcgaacc gacacctgga
    18601 tcgacaaccg atacaaacgt cgttccctca ggccagtaat ccaccgtctg aaagagacga
    18661 tagctcccct caaaaatatt ataaggcgtg atatcgtgcg tcaagtgatg gatttttaag
    18721 gttggagact cttctaaagc cactccaatc atagccgata ccgcaccatc aaccagacca
    18781 aagtctgatt gtaataccag taaattatta ttcattttat ctccttgtat atcctttatc
    18841 ataccatatt tcagagaaag tcgctaatag ctatttcaat tggttagggt atagttttaa
    18901 cttatagcaa atttcctact aaaaactctg gttattagct agtaggtgca ttttttcttg
    18961 aaaaagggta tgatagttac atcatgaaaa agtaggtttt attatgaaaa ttatccttgt
    19021 cggaggggga aaagttggtt ttgccctctg tcgctccttg gttgcagaaa agcatgatgt
    19081 tttgctgatt gagcaagacg aagctgttct caatcatatt gtcagtcgct ttgatatcat
    19141 tggtatcctt ggtaacgggg ccgattttgc cattcttgag caagccagcg tccaagattg
    19201 tgatatcttt atcgccctga ctgagcacga tgaagtcaac atgattgcag cagttctagc
    19261 caagaaaatg ggagctaaag aaactatcgt tcgggtgcgg aaccctgaat attctaactc
    19321 ttatttcaag gaaaagaata ttctcggttt ttctcttatc gttaatcctg agctcttggc
    19381 tgcccgcgct atcgcgaata tcattgactt ccccaacgcc ctgtctgtcg aacgctttgc
    19441 tggtggacgc gttagcctca tggaatttgt cgtcaagtcc accagcggtc tttgccaaat
    19501 gcccatttct gattttcgta aaaaatttgg taatgtcatt gtctgtgcga tagagaggga
    19561 gcatcaaatt atcattccaa gcggtgacat gactgtacag gataaagata gaatctttgt
    19621 cactggtaac cgtgtcgata tgatactctt ccataattat tttaaatcac gcgccgtgaa
    19681 gagccttctc atcgttgggg caggtagaat tgcctattat ctacttggta ttctcaaaga
    19741 tagtcgtatc gatacaaaag tcattgaaat caatcctgaa atcgccagct tctttagcga
    19801 gaaattccca aatctctaca tcgttcaagg agatggaacc gcaaaagata tcctgctgga
    19861 agaaagtgct caacactatg atgccgttgc gactctaaca ggtgtcgatg aggaaaatct
    19921 gattacatct atgttccttg acagggtagg tgtacagaaa aatattacta aggtcaatcg
    19981 taccagtctc ctcgagatta tcaatgcgcc tgatttttca agtatcatca cacctaaaag
    20041 catcgctgta gatacgatta tgcactttat tcgtggtcga gttaatgccc agtattcaga
    20101 ccttcaagcc atgcaccatc tagccaatgg ccaaatcgaa accctgcaat tccatatcaa
    20161 ggaagccaat aaaatgactg ccaaacctct ttctcaactg aaattgaaaa aaggggttct
    20221 tattgcagcc attattcgaa agggcaagac tattttccca actggggagg atatgttgga
    20281 agttggagac aagctcctag taacaacctt gttgccaaac atcaccaaga tttatgactt
    20341 gattgcgagg taaaaaatga ataaaagtat gattcgttac ctcctttcaa agttactttt
    20401 gattgaagct gttctcctct tggttcctgt ggctatcgct gtctattacc gtgaatcgag
    20461 ccaagtcttt acggccctct tttcgaccat agggattctc gtattgttag gcggttcagg
    20521 gagtttacag aagccaaaaa atcaacggat ttatgccaag gagggagtct tgatcgttgc
    20581 cctctgttgg atcctttggt ctttctttgg tggtctcccc tttgtctttt ctgggcaaat
    20641 ccccagcctt attgatgcct tttttgaaat tagttctggg tttacaacta ctggagcaag
    20701 tattttgaac gacatttcgg ttctcagccg ttccctcctc ttctggcgaa gttttaccca
    20761 cttgattgga gggatgggag tgcttgtttt tgcacttgct attatggaca atgccaaaaa
    20821 tagtcaccta gaagtaatga aggctgaggt tcctggtcct gtctttggta aggttgtatc
    20881 caaattaaaa aacactgccc agatcctcta tctcctttac atagccctct tttccctctt
    20941 tgtcatcatc tattatctag ccggtatgcc tctctacgat agttttgtca ttgctatggg
    21001 gacagcggga actggaggat ttaccgtcta taacgatgga attgcccact atggtagctc
    21061 actgattacc tatctggtta gtataggagt tttggttttt ggggtaaatt tcaatctcta
    21121 ctactacctt atgctccgtc gggttaaggc cttctttggt gacgaagaac ttcgggctta
    21181 cttggtcatt gtactggttt ctacaggctt gattagcctc aacaccctct acctctaccc
    21241 agggttttca aagagctttg aaatgacctt cttccaggtt tccaacatca ttacaacaac
    21301 tggttttgga tatggagata ttaccaactg gcccctcttc tcccagttta tcctcctttt
    21361 cctcatggca atcggtggct ctgctggatc aactgcaggt ggactcaaga ttattcgagg
    21421 cctcatcctt tcaaaaattg ccaaaaacca gattttgtca atcctatcgc cccaccgtgt
    21481 tttgactctc catgtgaatc aaacggtgat tgataaagat acccagcata agattctcaa
    21541 gtactttgtc atctatgcta tgattttgct agcgcttatc tttattgtca gcctagatag
    21601 caatgatttt ctggtcgtga ccagcgctgt ctttagctgt ttcaataata tcgggcctat
    21661 tctaggaacc acttctagtt tctcaatctt tagtcctatc tcaaaaattc tcctctcctt
    21721 tgcaatgatt gcaggccgct tggagattta cccaatccta cttctcttta tgaagagaac
    21781 ttggtctaag agataaaata caaaatccct ctttttacaa ttgtgaaaga gggattttta
    21841 tattaaaaag ggggaacgtt tttaaatcca agcctgtctg taagcaaagt tcttactcaa
    21901 ataaaagatg gaaaaactta ctacacagct tggtaatgct ccaatacaaa ttgtaaggct
    21961 ttacttggat tctttgttaa atgaatatat tccattcctc tggtagcaac tatctgaata
    22021 cctaatcttt ctgcatccac cttcatctct ctataataac tccgaacttg tggagccaga
    22081 ataattaaat cataaacacc cataatatca taatgagctc cgtacgctcc tgaattcgca
    22141 atcactctaa cttctgctaa ttgagcgccc tcgttaattg cattggctaa ttacgcactt
    22201 gttccagacc ctgcacaaag aaccagtact ttcaactcct tactttttat tacatctatc
    22261 tcaccaggca ttatttcact tgtatcctcc tctaaaataa tatcatttga gcttgcaata
    22321 tctacaacct gtagtaaata tctcgtattt agacaatatg aaaacaagac gacttccata
    22381 taggaaaccg ccttctcgct atgttgcatg aaactgtaaa agtggatgaa attgatagcg
    22441 gtagtcagat caagagacat cataactcta aaaagtcaca atatataagt tcatcctcgg
    22501 aaaaatatca ttctaattgt tgaaatggat atataaacag gggtattaac attaaatgct
    22561 catgaaacaa cgaatacagg tatcaaaact atgacaaaac gagtccctaa atttactaaa
    22621 gacactgctc aactttacac ctgtaaatgg ttgttgtata ataaagttac aaagatgtac
    22681 gaccacactg ttgtaaatca tagtgttcgc gaatatatta ctgatagcat ttctacaaat
    22741 acaattgaag agactggata ggctttaaac gaaatatgtc agtgttttgg cattcctagt
    22801 cttcatatca tttaaagaat tgtatagata aaatttttcc caatacagac actcgtaaca
    22861 actgcttcat ttttctacca acatatttag gaacaggata agatacaaga agattaatcc
    22921 atagctcagt tctataccaa tctaagacaa ataagctaaa aaatgattga taataagcaa
    22981 atagattcca aattttctct atctgctcat tttaataaac aatactagtg taactatcct
    23041 tccagtcaga aacttgtcaa atcacaccga aaactcttct aaaatttatc tcgttaggca
    23101 atcaagcaaa aactcgacga tagtacaaac attattatac agaattgact tcctaaatta
    23161 tatactttag taaggttttc ggataagaaa aaaggttcat tttacatttc taaacattct
    23221 tttctaagat gaaaaacaga atttttcgat tgtgatttaa agcaacaaga agattttcag
    23281 tgtcatccta tagatacgag ctaattaaga aaaactacat ttttgaatat aaactacaat
    23341 aatataaact aaattttata ggaggaagac aatggattgg tacgattata tgatacaggc
    23401 atccaaacaa tcacaattca acgcaagcca ttggtttcgc tatttgcgaa aagttatttt
    23461 tgaagactat tcttatttaa caaaccaaga tgtagaaaag ttgctagact ccaaagaact
    23521 aacccgtttt caaaaaatta gcttgaagta tgcctttcaa gagcatactc caactcataa
    23581 atatgtgatt tcattaaata aacctgctaa gttaaccaat gttcaaaaat tgatggagaa
    23641 atacaaacat ggataaaatg aaaccggtct tccaagccct aaataaggaa ttaattcagg
    23701 aaaatctgac tttaacaatt atctgtgtcg atggttatgt cttagaatat catggtttac
    23761 gtgccacaca agatgttgat gctttttatg accaaaatca gaaaatcaat gaaattattg
    23821 ctcgtgtagg aaaacagttt aatcttaaca tccacgaaga gttatggctc aacaatcatg
    23881 ttgcaaagca aatatgaaca aacaacctcc cttaagttta tgcgaatcct tgtactcatt
    23941 tgagaatctg accgttttag tagtccctat tgagtatgtg ttaggaatga agatgatgag
    24001 tatcagagag caggatttgc aagatattgg tgcaattatt aaatacaaaa actttcattc
    24061 accattcgat acctttaaat atttaaaaga catggaattt gatactattg acctctctgt
    24121 tctattagaa ggttttagtt atgcttatgg tatggattgg ttagaaaaat tttttaaaga
    24181 aaatcaagat aaacttcgcg aattttatta acagtatcaa acaagatgat tgtcaattag
    24241 ccagtcgtct tgttttttat gatgaaatga aataaaatct gaacaaatcg cttagagaat
    24301 tccagtcaat ttctagcgct gtttgagacg tttcagtgga ctatagtaaa atgaaataag
    24361 aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta gaaataaagg
    24421 tgtactattc tagtttcaat ctattatatt tcagattcgg tccactattc cttcccaaaa
    24481 acattgcata ttgcgccgaa ggaattgctc acactatccc aagcacaaaa ccctcagtcg
    24541 tttgaccgag ggttcctttt cattattcaa gaacttgatt agctcaatgc atccaaggcg
    24601 tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt ttgttctgga
    24661 gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc ttcgcctgac
    24721 atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg ttgtccaccg
    24781 ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc acgagtctta
    24841 ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc ataactaaag
    24901 tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt gttagatggg
    24961 ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc ttcgttgagg
    25021 tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac gttagatgtg
    25081 attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct acgtagacga
    25141 gttgtgtaag cttcgattaa ccattctgcc aattcgtttg aacgtgggtc atcttcaccc
    25201 cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc gtcacggatt
    25261 ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc aaatccacag
    25321 ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg aacagcttcg
    25381 tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta agtgtcagtc
    25441 aaccagtcaa gagatttttc aaagttcgct ttaactgatt caaattcaag aacttcgtca
    25501 cggattggtt cgatatcaaa tactttgtag tctttgtgaa catcgtcgta accaccattc
    25561 aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg gatgttgtgg
    25621 cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca gctcatttca
    25681 ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga gtgtttgtgg
    25741 ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca aagaactgtc
    25801 aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg gtagtccatc
    25861 ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt gataaaggtt
    25921 gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac tgtacgaagt
    25981 ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt accacgagca
    26041 aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga tgtagcagca
    26101 ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat tgcttctttc
    26161 acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg aacaacttgt
    26221 tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc ttcatcgatt
    26281 tctttgattg cattccagtc atttactttt tcttgcatca agtagtctgc accgtaaaga
    26341 gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg aagaccagtt
    26401 acagtgtgtg cgtgacgagc gcgacgaata tttgaagtgt aggcacggaa aataccgtcg
    26461 ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg ttcgtatcca
    26521 ttttctttca aagtagtttc agccatacgg ataccacctt ttggcatgaa gttcaatttg
    26581 aagagttcat cgttttggat accgaagata acttcatttt ctttgtcgat aaatccagca
    26641 gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc ttcgtagtgt
    26701 gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg tcctgcaagg
    26761 aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaatcgtga tacacttgct
    26821 ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat atcttgtgct
    26881 tcaacaactg tcttaacaac catattaatg tcctcttttt tctagtaaca gtcatctgtt
    26941 acattcataa gacaagtata ccatatagta accgatttca acaagtgaaa attccctatt
    27001 tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta tatttttgaa
    27061 aaaataaagt ccttttttct ttttttcaga aaaaagggta taataaaaga aaataagcag
    27121 taacactcaa tggaaatcga aaagcaaact aggaagctag ccgcagattg ctcaaaacac
    27181 tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag agtataaaaa
    27241 ggtgctaggc atgttgattt ttcctttgtt aaatgatttg tcaagaaaaa tcatccatat
    27301 tgacatggat gccttttttg ctgcagtgga aatcagggat aatcctaaac tcagaggaaa
    27361 acctgtcatt attggaagcg accctcggca aacaggtgga cggggagtcg tttctacctg
    27421 tagttatgag gcaagagctt ttggtgtcca ttctgccatg agttccaagg aagcttatga
    27481 acgttgtccc caggctgtct ttatctcagg gaattatgag aaatacaagt ctgtgggact
    27541 ccagattcga gctattttta agcgctatac agatttgatt gaacccatga gcattgacga
    27601 agcctatttg gatgtgacag aaaataaact cggtatcaag tcagcggtca aaattgctcg
    27661 cctcattcaa aaagatatct ggcaagaact ccatctaact gcttccgcag gcgtttctta
    27721 caacaaattc ttagctaaaa tggcgagtga ttatcaaaaa ccacatggtt tgacagtgat
    27781 tctacctgaa caggctgagg attttctcaa acaaatggat atttccaaat ttcatggagt
    27841 aggaaaaaag acagtagaac gtcttcatca aatgggcgtt tttactggtg ctgatttact
    27901 tgaagttcct gaggtaaccc taatagaccg ttttggtaga ctaggctatg atctgtatcg
    27961 aaaggctcgt ggcattcaca actctccagt caaatccaat cgcatccgta aatcaatcgg
    28021 caaggggaaa acctacggga agattctcct tgctgaggaa gatatcaaaa aagagctgac
    28081 tcttctatca gaaaaagtcg ctctcaatct acatcaacaa gaaaaagctg gaaaaattgt
    28141 cattttgaaa atccgctacg aggacttttc aactcttacc aaacgaaaaa gtcttgctca
    28201 aaaaacacaa gatgctagtc agataagcca aatagccctg caactctatg aagaattaag
    28261 caagaaagaa agaggtgtcc gcctattggg gattaccatg actggatttt aaagctcaat
    28321 gaaaatcaaa gagcaaacta ggaggctagc cgcaggctgc tcaaaacact gttttgaggt
    28381 tgcagataaa gctgacgcgg tttgaagaga ttttcgaaga gtataaaacc ttgaagagtt
    28441 gccccttcaa ggtttttctt atacaaataa acggacaaaa ctgtaaagta gcaaaacact
    28501 accaagcacg atacggtatt taccaaaaag ggtgaagtcg tgttttttca catagctggt
    28561 caagaagcga atagccacca tgctgaccgc aaaagctact cccatcgcga ccaagagcaa
    28621 aaacaattgc ccaaagctca agagttctcc ggctttcaca aatttgaaaa tctttaaggc
    28681 actagctcca aacataacag gaatcccaag atagaaggta aattctgtca caactgaacg
    28741 actggttcca tttaacaaac caccgacaat cgttgcacct gaacggctag tccctggtaa
    28801 aagagcaaga acttggaaga gtccgatata gaaagcggtc gtataaggaa gcttgtccaa
    28861 ctctgttaca cttggctcga tagcacgcgc tttattgcgc ttttccaaat agatgaaggc
    28921 aaccccgtag ataatcaaca tgagagcaac tgaaaccatg ttatggaagt gggtatcaaa
    28981 ccaatcatca aatttaaaga caccaagtaa aggtaaagta gcaatcaaga ccttcaacca
    29041 tagtctccaa gtcttacgaa cttcctgttt gtccttagtc ggtttaaaag gattgagctt
    29101 gttaaaataa atcaccataa ctgctaaaat agcaccaagc tgaatcacga cattaaacat
    29161 ggacataaag gcttcatttt gattttggta ttggatgaat tcctctgcta aaatcaagtg
    29221 acctgtactg gaaatcggca accattccgt aattccttca acaatcccga agaagataga
    29281 ttttaaaatt tcaataagat acatagatta ctccctatat tataattagc gcagttagct
    29341 actgccaaag cccaagtggt atacttggaa taagccactg tggattagtt catttcctcc
    29401 aatcgcttga cgatttccga aaggatctaa ccacagcttt tgtttcaatt ggtaatgagt
    29461 ttgataacgc atagacgttt tatctcgtct aaggtaacaa ggcaaaaagt tcgtggataa
    29521 ccaagtagac ttgaaatact atatctggag gtactcccat gctttatgtg ggcattgata
    29581 tcgctaaaaa taaacacgat gttacagcct tgaatgttcc aggaaaaact gttcttaaac
    29641 cactcacttt ttcaaataat aaagctggtt ttgaactctt agatctgtct cttcgacagc
    29701 tcaaccaaga ctgtctcatc gctcttaaac ttctttctga ccccaatcgt gaacaatttc
    29761 aacacgataa tcggcaagta gacctaaaaa tactggctag acatattcat cgtctcaaga
    29821 aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc tttcctgagt
    29881 tggataaaat cgttggaaag cattcagaat atacctacca actcttgacg cgctacccta
    29941 atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag cgattgaccg
    30001 cttctaaaat tcaggatatc ctctcagtcg cacctcattc tatcggaaca acatctcctg
    30061 ctcgtgaatt cgaaatcatc gaaaacatca aacattacaa gaggctcatt gacaaggcga
    30121 aaaaatgtgt caatgacttg atggctgagt tcaactcggt catcacgacg gttactggga
    30181 ttgagaatcg tttaggggcg gtcattttag ccgagattcg aaatattcat gcctttgata
    30241 atcctgctca attacaagct ttcgctggac tggattcttc tatttatcag tcaggtcaga
    30301 ttgatttagc aggaagaatg gtcaaacggg gttcccctca tctgcggtag gtactcatac
    30361 aagctgccaa agcatgccct cgcttttcac ctgcttttaa ggcctatctt aagactaagt
    30421 tagaataagg aaaacattac aatatagcca tcatccacct tgcaaaaaaa cttatccgaa
    30481 ccctgtttta tatcctaaaa aagagctgcc atttgacgaa caaaaagtga tataatttct
    30541 gaaattaaca caggattacc tttgaaaaaa tggacttttt caatagcttt ttgccgtgct
    30601 ctaaaatcat cgccaaatca tcaaattgaa ataagaaata gtttagataa aactattgac
    30661 ttttcttata gtttgtcttt tttctatctt ccattatatc atactttttc agtctatggt
    30721 agctctcttt aaaaggcacc gatactgccg ccacctccgc ctccagagaa gccaccacca
    30781 gaacttccac ttccagaaga tacagagtag gtgcttgctg tatttgcgac actagcataa
    30841 tggctcattt gtgctgttga atgataaaac atactgtgcc agccataagc tacatagaga
    30901 ttgatatctg gattttccac ttgaatctga tgaaccttca tcaaatgact aaccttgtcc
    30961 gcatagccaa ataaggtcgc atagaccaag aggcgattcc agaccacaat actttccagt
    31021 tcagcctgat ccaatcgtgc aatctcacgc aacatatttt caaaactggt ccagagatag
    31081 tagacctcag ctcccgcttc atttagaaca ccatcacgat tatctagtcg aagcttccaa
    31141 taatagaaaa cagacaaaac taaccctaga aaaccaagta ttggcaaagg gaggtaaaga
    31201 tagccatgaa cgtctaaact gtacaagaac aaaccaaatc cgataaatag gggcaggata
    31261 gtcaaggcac ccatacccac ttgcaaggcc ttttccccac cagttaaagg acgataataa
    31321 tctgggagcc cccagaagga aactcgtttt ctcactcctt cttgcatctg gttcaatacc
    31381 tcttcaaaag aagatttgag ttgaagccct cttgcttgaa tccgtttttc atcagaaact
    31441 ttggctctac gataaagact atcagatacc ttgtaatccg caaacaaatt ggaaagagtt
    31501 tcttcttttt tacctgaaaa agctagattt aggcagtctt tctcaaagct tgacaaacca
    31561 tcttctttta ctagcctcaa accaactgca tctccttctg aaatgataga gacattccca
    31621 cggtctatca catctagcaa ggtagcttga ataagttgat caaaggtgaa ttttccagct
    31681 cccttgacca agggactcac ttcctccaag gaggtcgagt agactgcttc tgataaaacc
    31741 ataggctcta attccattgg tggttcatag agacgatgat ttttggcata tttgactgaa
    31801 ggagtggtct ttcttctata aataaaatag aagcagacac tcaataacaa ggagatagaa
    31861 agtatcgaag ggaggaccca agtaacgagt tgtttactct gatctttttc tctaacaatc
    31921 gagtcttcta tcttattaaa ctcttctaaa cgattccctt tcaatccctg atccctagcg
    31981 ctagcaaaat cggtccgagg ccaataggca tgcaactcaa ctccacgctt agccggaaga
    32041 ttgtctaaac ggatagtata atcaaggtta ctcttttcaa tcgttccctc tctaaaaagt
    32101 ttccctgtat ggaaaaagag tttttcagcc cccttgtctc cccttacatg aaattcaaac
    32161 ttttcaatag actctgaact atctgtcaga ggttgccaat ttaattcagc gatatcatca
    32221 taaaggaaaa gtaaattttt taagttccag acgaggtcaa cttcaactat gtcgccctcc
    32281 tgacctggat tatagactct cacagtataa ccatccgctt cttctgttac ttcgctagtc
    32341 acatctgcta gttctgcacc gtttttcgcg gcctgaacct ttggatgagg gtcaatgtca
    32401 aacccgctag gcatcttacc agcacgtcca agtcccacga tttgtccctt aaagtcctcc
    32461 tcaaactggt aaactatctt ctgtctaaac tctgccgtat tatctgcatg aatatacaaa
    32521 tccccttgat aagagtttat cttgaaatca atggcaaaaa cagagagtgg aagaaggcaa
    32581 aacaagccta acaccagtaa gaaaaaagtt tttttcatca actaagcccc ctttttatct
    32641 ttcttatcat tatagcattt tttcgtaagt aaaggcttac ttatgttgaa aaattacgca
    32701 tttttcgata aaataggaga cagttatttt ttaatagatc agaataggag aaatcatgag
    32761 aaaaatatac ttatctattt tcacaagtct cttgctgatg ctaggacttg tcaatgttgc
    32821 tcaagccgat gaatatttac gcatcgggat ggaagcagca tatgctccct ttaactggac
    32881 ccaggatgat gatagcaacg gagctgtcaa aatcgatggg accaatcagt atgccaacgg
    32941 atacgatgtt caaatcgcca agaaaatcgc taaggactta ggtaaagaac ctttggttgt
    33001 taaaaccaag tgggaaggtc tagtccctgc ccttacttct ggtaagattg acatgattat
    33061 cgcaggtatg agtccaactg cagaacgcaa acaagaaatt gccttttcga gcagttacta
    33121 cactagcgaa ccagttttgc ttgtcaaaaa agattctgcc tacgcaagtg ctaaatcttt
    33181 ggatgacttt aacggtgcaa aaatcacttc tcaacaaggg gtctacctct acgacttgat
    33241 tgcacaaatc ccaggtgcta aaaaagaaac agccatggga gacttcgctc aaatgcgaca
    33301 agctcttgag gctggtgtca ttgatgctta tgtttctgaa cgtccagaag cactgactgc
    33361 tgaagctgcg aactctaagt tcaagatgat tcaagtagaa cctggtttca aaactgggga
    33421 agaagataca gctatcgcta tcgggcttcg taaaaatgac aatcgtatta gccaaatcaa
    33481 tgccagcatt gaaaccattt caaaggacga ccaagttgcc ctgatggatc gtatgatcaa
    33541 ggaacaacct gccgaagcta caacaactga agagactagc agtagtttct ttagccaagt
    33601 cgctaaaatt ctttctgaaa actggcaaca actcttgcgt ggtgctggta tcactctttt
    33661 aatctctatc gtcggaacca tcataggtct cattattgga cttgccattg gtgtcttccg
    33721 tactgctcct ctctctgaaa acaaagccat ttatggcctt caaaaactag tcggctgggt
    33781 tctcaatgtc tacattgaaa ttttccgtgg tacgccaatg attgttcaat cgatggttat
    33841 ctactatgga actgcccaag ctttcgggat caaccttgac cgtacactgg ctgctatctt
    33901 catcgtttca atcaataccg gtgcctacat gactgaaatc gtccgtggtg gtatcctagc
    33961 agttgacaag ggacaatttg aagctgcgac tgctcttggt atgacccata accagaccat
    34021 gcgtaagatt gtcctacctc aggtagtccg taacatccta cctgcaactg gtaatgaatt
    34081 tgtcatcaat atcaaagata catctgtatt gaacgttatc tctgttgtcg aactttattt
    34141 ctcaggaaat accgtggcaa cacaaaccta tcaatacttc cagacattta caatcatcgc
    34201 cgtgatttac tttgtcctca ccttcaccgt aacacgtatc ctacgcttta tcgagcgcag
    34261 aatggacatg gatacctaca ctacaggtgc taaccaaatg caaacggagg atttgaaata
    34321 atgacacaag caatccttga aattaaacac ctcaaaaaat cctatggaca aaacgaagtg
    34381 ctaaaagaca tttctctcac tgtccacaag ggagaagtta tttctatcat cggaagctct
    34441 ggaagtggga aatcaacctt cctacgctcc attaacctac ttgaaacgcc aactgatgga
    34501 caaatccttt atcatggaca aaacgtcctc gaaaaaggct atgacctcac gcaataccgt
    34561 gaaaagttag ggatggtttt ccaatccttt aacctctttg aaaatctcaa cgttcttgaa
    34621 aacacaatcg tcgctcagac aactgtcctt aaacgcgaac gcacagaagc tgaagaaatt
    34681 gccaaagaaa acctggaaaa ggtcggcatg ggagaacgct actggcaagc taaacccaaa
    34741 caactctcag gtggtcaaaa acaacgtgtg gccattgctc gtgccctttc aatgaatcct
    34801 gacgccattc tctttgatga accaacatca gctctcgatc cagaaatggt tggagaggtc
    34861 ctcaaaatca tgcaagatct ggctcaggaa ggcttgacca tgattgtcgt aacccatgaa
    34921 atggaatttg cccgtgatgt ctctcaccgt gttatcttta tggataaggg cgtgatcgct
    34981 gaagaaggta aaccagaaga cctcttcacc aatcctaaag aagaccgaac aaaagaattt
    35041 cttcaacgtt atctca
//
LOCUS       DBEJJE010000019        34219 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEJJE010000019 DBEJJE010000000
VERSION     DBEJJE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.19"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(193..1179)
                     /locus_tag="ACL3F5_000933"
     CDS             complement(193..1179)
                     /locus_tag="ACL3F5_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0514762.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1189..1989)
                     /locus_tag="ACL3F5_000934"
     CDS             complement(1189..1989)
                     /locus_tag="ACL3F5_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0514763.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2242..3084)
                     /locus_tag="ACL3F5_000935"
     CDS             complement(2242..3084)
                     /locus_tag="ACL3F5_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0514764.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3086..4378)
                     /locus_tag="ACL3F5_000936"
     CDS             complement(3086..4378)
                     /locus_tag="ACL3F5_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0514765.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4489..5760)
                     /locus_tag="ACL3F5_000937"
     CDS             complement(4489..5760)
                     /locus_tag="ACL3F5_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0514766.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6295..7827
                     /gene="malQ"
                     /locus_tag="ACL3F5_000938"
                     /pseudo
     CDS             6295..7827
                     /gene="malQ"
                     /locus_tag="ACL3F5_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7853..10111
                     /gene="glgP"
                     /locus_tag="ACL3F5_000939"
     CDS             7853..10111
                     /gene="glgP"
                     /locus_tag="ACL3F5_000939"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR0514767.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDSAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11156..11728)
                     /locus_tag="ACL3F5_000940"
     CDS             complement(11156..11728)
                     /locus_tag="ACL3F5_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514768.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHVAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12506..13354)
                     /locus_tag="ACL3F5_000941"
     CDS             complement(12506..13354)
                     /locus_tag="ACL3F5_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0514769.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            13506..13784
                     /locus_tag="ACL3F5_000942"
     CDS             13506..13784
                     /locus_tag="ACL3F5_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0514770.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13786..15849
                     /locus_tag="ACL3F5_000943"
     CDS             13786..15849
                     /locus_tag="ACL3F5_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0514771.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15927..17183)
                     /gene="tyrS"
                     /locus_tag="ACL3F5_000944"
     CDS             complement(15927..17183)
                     /gene="tyrS"
                     /locus_tag="ACL3F5_000944"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0514772.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17325..19790
                     /gene="pbp1b"
                     /locus_tag="ACL3F5_000945"
     CDS             17325..19790
                     /gene="pbp1b"
                     /locus_tag="ACL3F5_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0514773.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19855..20766
                     /locus_tag="ACL3F5_000946"
     CDS             19855..20766
                     /locus_tag="ACL3F5_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0514774.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20996..21694
                     /gene="dapD"
                     /locus_tag="ACL3F5_000947"
     CDS             20996..21694
                     /gene="dapD"
                     /locus_tag="ACL3F5_000947"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0514775.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21762..22892
                     /locus_tag="ACL3F5_000948"
     CDS             21762..22892
                     /locus_tag="ACL3F5_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0514776.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22904..23443
                     /locus_tag="ACL3F5_000949"
     CDS             22904..23443
                     /locus_tag="ACL3F5_000949"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0514777.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23427..24104
                     /locus_tag="ACL3F5_000950"
     CDS             23427..24104
                     /locus_tag="ACL3F5_000950"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0514778.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24171..25070)
                     /gene="galU"
                     /locus_tag="ACL3F5_000951"
     CDS             complement(24171..25070)
                     /gene="galU"
                     /locus_tag="ACL3F5_000951"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0514779.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(25092..26108)
                     /locus_tag="ACL3F5_000952"
     CDS             complement(25092..26108)
                     /locus_tag="ACL3F5_000952"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0514780.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEIRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26625..26759
                     /locus_tag="ACL3F5_000953"
     CDS             26625..26759
                     /locus_tag="ACL3F5_000953"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514781.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(26874..27308)
                     /locus_tag="ACL3F5_000954"
                     /pseudo
     CDS             complement(26874..27308)
                     /locus_tag="ACL3F5_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27376..28026)
                     /gene="phoU"
                     /locus_tag="ACL3F5_000955"
     CDS             complement(27376..28026)
                     /gene="phoU"
                     /locus_tag="ACL3F5_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0514782.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLNMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(28041..28793)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000956"
     CDS             complement(28041..28793)
                     /gene="pstB"
                     /locus_tag="ACL3F5_000956"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0514783.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28795..29610)
                     /gene="pstA"
                     /locus_tag="ACL3F5_000957"
     CDS             complement(28795..29610)
                     /gene="pstA"
                     /locus_tag="ACL3F5_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0514784.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29603..30466)
                     /gene="pstC"
                     /locus_tag="ACL3F5_000958"
     CDS             complement(29603..30466)
                     /gene="pstC"
                     /locus_tag="ACL3F5_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0514785.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30584..31459)
                     /locus_tag="ACL3F5_000959"
     CDS             complement(30584..31459)
                     /locus_tag="ACL3F5_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0514786.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31626..32957)
                     /gene="pnpS"
                     /locus_tag="ACL3F5_000960"
     CDS             complement(31626..32957)
                     /gene="pnpS"
                     /locus_tag="ACL3F5_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0514787.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKGNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32958..33665)
                     /locus_tag="ACL3F5_000961"
     CDS             complement(32958..33665)
                     /locus_tag="ACL3F5_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0514788.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33749..>34219)
                     /locus_tag="ACL3F5_000962"
     CDS             complement(33749..>34219)
                     /locus_tag="ACL3F5_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0514789.1"
                     /translation="KEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSIYF
                     LLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYCVP
                     KGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
BASE COUNT        10099 a         6457 c         7320 g        10343 t
ORIGIN      
        1 gtgttttgag caacctgcgg ctagcttcct agtttgcact ttgattttca ttgagtataa
       61 aaagatcttg ggaaaagact caatttcagt agaaaaggaa gtaaatcttc ccacaataaa
      121 acgcatagta tcaagttttt tcaatacctg atactatgcg tttttgcttt taacgacttt
      181 ttacccagtc tcttattttt cgataatttt gtgggcgatc aattgacggt aacaaatttg
      241 tttattgttt ttattatcat taataatctg gagaatagtt tcaagggaaa cacgaccaag
      301 ctctaaacta ttgatatcga cataggctgc caagttgagc ttgggattaa ccgagtcaaa
      361 gctgagaaca gggacatcca gctggtgttt ggcaatatag ttacaaacac cttcagctag
      421 gaggctatcg gttgtgatga tagcatcaat ttgtggatcg tgcttgaata atcgcttgct
      481 aaatttatag cccttttctt ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt
      541 ggtaagtttg taatgtttaa gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa
      601 gagcttttta cttcctccga taaaggcaat gcgtttgcag ccttttttga tgaaatattc
      661 agtcgcatca aaaccagctt gaacattgtc gttgtcgaca agtgggatga aaggagatag
      721 agatttacct aagataagga aggggaactg ttcttctgcg acgagtttta cgagagggtc
      781 ttcttcttgg gcatagagaa agattagccc atctacacgc ttgccgtaga ccatttgtga
      841 aatagcgttg agacgctcct tctcatcttt ccctgttgct atctgaatgg catagtggtt
      901 ttcagatgcg acttgagaga tgccacgtag aaccgatgga aagaaaggat tctggtagaa
      961 ggcgtctgag tcatcaggaa gaactaatcc gataacctga gtatagctgc ttaccaagct
     1021 acgagcgttg aggtttgggt ggtagttgag ttccttcata gctttgcgaa cgcgtttttt
     1081 tgtttcgtcg ctaatggttg atttattttg aataacacgg gttacggttg aaggcgaaac
     1141 accagcagcc ttggccacgt ctttaatcgt aacgggcata aaaatctcct atttatggta
     1201 atttggatca cggaaatgtg ttttataaaa gatagtgacc agatacagaa caaaaagaat
     1261 attttgtaca gtaatcaggg ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat
     1321 cagagtcggc aatcctaaac agttcaagat aaagtgatag cactctttaa aggttctaaa
     1381 tgaaaagagg cgtgatttct tagtgatata aaggagaaga ctagctccta gagagacgat
     1441 aaagaaattc aaaccaaaga ggaagctcgc accgagaact aggaagaggc tgatatagac
     1501 acgattttgt tggtaccagt ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa
     1561 actctcagtc tgaatggctc ggtaagagat gcgggtcagt tccttgcttt ccttgctgat
     1621 gactagctca tttgtatcga aatgcagttg caagtcctta ggtaattcct tgatttgact
     1681 tggaccaatc acaacagaag gagcttgact agctgttcca gtataagtta atgtgccatc
     1741 gacaattgta gcatgttcag agagatcctg gacaacctca tttgtcagag gttcatagac
     1801 attatcgata aaagtttcta gcggataggt ctcctgggag ctgttttgga tagcaatggg
     1861 taccatagat aagctgataa ggaagatact ggtaaagaga agttgaaacc agttgagctc
     1921 gaaacgtttg gacaggggct tacgaaaccc ccaaatactt gaaaaatagg aaaatggata
     1981 tggaagcata ggtatctttc taaaaggtgt tttctatatg agtattatta tatagagaaa
     2041 tgcgctttat ttcaagtcta ggagaaaaat tgcttgctac aaggatatta tttacagtga
     2101 caattgctaa taatcaatga aaatcaaagt gcaaactagc cacaggttgc tcaaagcaca
     2161 actttgaggt tggagataaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg
     2221 aaaaagggtg gcggggataa attatccctt gtcgccacca cttgtaagtc ctgaaacaaa
     2281 gttcttttgt aggaagaaga agagaataca gattggaagg gcgatgagga tagcacctgc
     2341 tgagaagtag gcaatcttca agtttttcgc attgttaacg aaggtttgga gacctacggc
     2401 aacagtaaag tattctttct cacgaagcaa gaaactagag aggatgtagt ccccgaaagg
     2461 tcccatgaag gcccagagag cttgtacggc aaccattggg cgaacaagtg gaagaacaat
     2521 ttgccagaag cggcggaagt gtcctgcacc gtctagtttt gcagattcgt ctaaagacat
     2581 tggcactgta tcgaagtagc ctttcatgag ccaagcattc atcgggatac caccaccaac
     2641 gtagaggaag atgaggaacc agctgtggtt aagggcgttc aacataagcg ccataacgaa
     2701 gaaggctgtc aaagcggcca tagttggcac catttggatg atcaagaaga agaccaaact
     2761 ttgtttacga gccaagaagt tgtaacggct gtaagcataa ccagcaagta cgatgatact
     2821 tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta
     2881 caaggtttca gtgaagaggc ctttaaagtt atcaaaattg aggtcgatat tagtatctag
     2941 tttaaaggct gagacgttac ctgctttaaa ggctgacata atggtaatca acagtggata
     3001 gataattaca attgatagac caatcaggta aaggtaagta aggctttgag tcagtctacg
     3061 tttgagttta attgagttat tcatcttaga cgtcctccat atcaaatgcg tgtagtttct
     3121 tgaatgcgat catagagatt gagatgacaa tgatagagat aatcaaggta acagctgccg
     3181 ccattgagta ttgaggagat gtacctgttg tcaaacggta gatccatgag atcaagatat
     3241 cggttgaacc agctccacct ccgacactac caggtcctcc accattgaag aggtacatga
     3301 tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca
     3361 aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg tcaatataag
     3421 ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc caaagtcaaa acgtagatgt
     3481 atgggaatcc gagccaacct tgcatcataa tcaaggcaat cttagtccaa gttgggtctg
     3541 ttttccaagg aataagagct ccatcaagga aaggaaggaa tttagccaag attggcaata
     3601 cttgagtgtt gatagcaccg acactatcgt taaacatgtt tgagaatgtc aagatagtga
     3661 tgaaggctgg gacagcccaa ggaagaagga aaataacacc aaagatacgt tttcctttga
     3721 taaatggttg gttggcaatg atagctgtga agataccaat tacgatttgt aaagtagaag
     3781 ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac
     3841 tcaagctcca aatgtttgta aagttggtca aaccaaccca gtccaacaac ttgtttggtg
     3901 gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata actgggaaga
     3961 taatcgcgaa ggtcatggca acataagatg gaatgatcaa gaggtaaggg aagccatttt
     4021 cataaatccc tttgatcatg tctttgagtg tgcgtggaac tggaattcca ttgttaatgc
     4081 gttttgcaat cgtatgtgca tctttgatat ttgagaaata aaagagtaca taaacgatta
     4141 caaagattag atggaaggca ccacgaatca gcataaagag ggaattatca cgacctggtt
     4201 tgtcaccaag agtgatgagg ttgctcaatt caggggttgc aagtgctagg aagtaaagga
     4261 caaatacgat ggttacacca aggaagataa aacctttggc tttttgttta ttgtaaatct
     4321 gtcctaaccc aggaatgata gacagcaggg ctgctttact aggttgttgc ttttccatat
     4381 taactccttt cataggatac tactttttta taagaaagct aaattatttg tgtctctatt
     4441 gataaattca aagggggatt tgatttccac cccccttgaa caaatttttt attcaccaaa
     4501 tttttgtttg attgtttctt tgatcaatgt tacagcatcg ttagcagctg ttttagcatc
     4561 tttttgacca cttacagcat caaagagcat atttttcgct ggatcccaaa ctgcagacat
     4621 ttgagagatg tttggcagtg gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa
     4681 ctcatcgttt ttaccttcag cgtatgaacg agcctcagta ttagctggga tttcgttagt
     4741 cttatcatat aatacttttt gttgttcagt tgcaacaagg aagtctacaa atttttgaga
     4801 agcttcaagg ttcttaacgg cttgaggaat gacccaagct ttaccaccac cgaatgcagc
     4861 atattctttt ccatttggaa gagttgggat agttgcaact ccgtagttta ctttagcatc
     4921 tttaaaggct tgagctttcc aaggtccgtc gatgatagca gctgttttac cttcttggaa
     4981 ttgagtttgg attaagtttc cagcaccttc tgtatcttgc atacctttag gccatttttc
     5041 gtaccaagat ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc
     5101 tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa gaagtccata
     5161 tgtatagtag aagtttgtcc agtcagctag gaaggcagta gttttaccat cttcaccagc
     5221 gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc
     5281 tttcaccaag tctttgttgt agtacataac aagtgactcg ataacggcag gagcaccgta
     5341 aactttacca ttagcagctg ttacaagaga tttagttgtg tcgtctgttt tagcaccatc
     5401 gctcaatttc acttctgaaa gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg
     5461 agccatcata acatcaggga cattaccaga ttggttgtca agagaaagtt tatcaagacc
     5521 tcctagagca tcaccagttt taagagtgac ttttactcca gcttcttttt cataagcttt
     5581 agcaacctct tcaatatagc tcttatatcc ctcgtctaca tatacagtga gttctttgac
     5641 ttcagatgaa ccagaatcag caggcttatc agcagttttg cttccgcaag ctaccaaaag
     5701 caagctagca agtgtagcag ttccaagcac cgcagtgctc ttcataaatt tagatgacat
     5761 agtgtattcc tcccaaagaa tagcaagttt tattgataag gaaacgcaaa cgttttcctt
     5821 tatgagctta gtatagcaca aatagaaaac ggttgcaagt attttttgta aaaattttaa
     5881 aaaattttta agcttgattt gatagcataa ttttacattt taatagaaga aaagtatgaa
     5941 atagataaga atacagtatt tttaataaaa atatatggaa tctgtctaaa gagggaaatc
     6001 aggaggggct acctccctgt ttctaatccc tatctatttt ctatagacgt ttgtgctttg
     6061 ttgcatataa attcaagctc cctaaggagg ttttgtactt tgtagactgt ctcgtgagag
     6121 tcaaacttta ggattagata gttttaagtt atctttgcta aaatgagtta gtctccttaa
     6181 aaataatcaa aaaagttttt taaaaacgct tgcaattatg cttgaaaagg agtatactta
     6241 taagtaacgc aaacgtttgc gtctgaaaaa tacgcaacgt tccattattt taacacacga
     6301 ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc tcttccagga
     6361 gcttacggaa tcggatcatt tggtcaaagt gcttacgact tcgttgattt cttggtccgt
     6421 acaaaacaac gttactggca aatccttcca ttaggagcaa ctagttacgg ggattctcct
     6481 taccaatctt tctcagcctt cgcaggaaac actcatttta tcgatttaga tatcttggtg
     6541 gagcaaggtt tgttgggagc gagtgacctt gaaggagttg actttggtag cgatgcgtct
     6601 gaagttgact atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa agcggtgaaa
     6661 cgtttctttg aagtcggaga tgttaaagat tttgagaaat ttgctcaaga caaccaatca
     6721 tggcttgagc tctttgctga gtatatggct atcaaagagc attttgacaa tcttgcttgg
     6781 actgaatggc cagatgcaga tgctcgtgct cgtaaagctt cagcacttga aagctatcgt
     6841 gagcaattgg cagacaagtt ggtttaccac cgtgtgactc aatacttctt cttccaacaa
     6901 tggttgaaat tgaaagctta cgctaacgac aaccacattg aaatcgttgg ggacatgcca
     6961 atctacgtag cggaagattc aagtgatatg tgggcaaatc cacatctctt caaaacagat
     7021 gtcaatggta aggctacttg tatcgcagga tgcccaccag atgagttttc tgtaactggt
     7081 cagctttggg gtaacccaat ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg
     7141 tggattgaac gcttgcgtga aagcttcaaa atctacgata tcgttcgtat cgaccacttc
     7201 cgtggcttcg aatcttattg ggaaatccct gctggttccg atacagcagc acctggtgag
     7261 tgggtgaaag gtccaggcta caagcttttt gcagccgtta aggaagaact tggtgagcta
     7321 aacatcatcg cagaagacct tggcttcatg acagatgaag tgatcgaatt acgtgaacgt
     7381 actggcttcc caggaatgaa gattcttcaa tttgccttca acccagaaga cgaaagcatt
     7441 gatagcccac acttggcacc tgctaactca gttatgtaca caggaacaca cgataacaat
     7501 acggttcttg gttggtaccg taatgagatt gatgatgcga ctcgtgagta catggctcgt
     7561 tacacgaacc gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac agtattttca
     7621 tcagttagct ttatggcaat tgcaactatg caagatttac tagaattgga tgaggcagct
     7681 cgtatgaact tcccatctac ccttggtgga aactggtctt ggcgtatgac tgaagatcaa
     7741 ttgacaccag ctgtcgagga aggtttgctt gacttgacaa caatttatcg ccgaattaat
     7801 gaaaatttgg tagatttaaa gaaataagac aataatcagg agacaactaa acatgttatc
     7861 actacaagaa tttgtacaaa atcgttacaa taaaaccatt gcagaatgta gcaatgaaga
     7921 gctttacctt gctcttctta actacagcaa gcttgcaagc agccaaaaac cagtcaacac
     7981 tggtaagaaa aaagtttact acatctcagc tgagttcttg attggtaaac tcttgtcaaa
     8041 caacttgatt aaccttggtc tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa
     8101 agacttgatc gaagttgaag aagttgaatt ggaaccatct cttggtaatg gtggtttggg
     8161 acgtttggct gcctgcttta tcgactcaat tgctactctt ggtttgaatg gtgacggtgt
     8221 tggtcttaac taccactttg gtcttttcca acaagttctt aaaaacaacc aacaagaaac
     8281 aattccaaat gcatggttga cagagcaaaa ctggttggtt cgctcaagcc gtagctacca
     8341 agtaccattt gcagacttta ctttgacatc aactctttac gatattgatg ttactggtta
     8401 tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg gattcagttg attcttctat
     8461 tattaaagat ggtatcaact ttgacaagac agatatcgct cgcaacttga ctctcttcct
     8521 ttacccagat gatagtgacc gtcaaggtga attgctccgt atctttcaac aatacttcat
     8581 ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca
     8641 tgaccttgct gactacgcag ttgtccaaat caacgatact cacccatcaa tggtgattcc
     8701 tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt
     8761 tcgtagcatg actgcctaca ctaaccacac aatccttgct gaggcgcttg aaaaatggcc
     8821 tcttgaattc ttgcaagaag tggttcctca cttggtacca atcatcgaag aattggaccg
     8881 tcgtgtgaag gcagagtaca aagattcagc tgttcaaatc atcgatgaga gcggacgtgt
     8941 tcacatggct cacatggata tccactacgg atacagtgtt aacggggttg cagcacttca
     9001 tactgaaatc ttgaaaaatt ctgagttgaa agccttctac gacctttacc cagaaaagtt
     9061 caacaacaaa acaaacggta tcactttccg tcgttggctt atgcatgcta acccaagatt
     9121 gtctcactac ttggatgaga ttcttggaga tggttggcac catgaagcag atgagcttga
     9181 aaaacttttg tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc
     9241 tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc
     9301 aaattctatc tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa
     9361 cgctttgtac gtgatccaca aataccttga catcaaagct ggtaacatcc ctgctcgtcc
     9421 aatcacaatc ttctttggtg gtaaagcagc tccagcctac acaatcgctc aagacattat
     9481 ccatttaatc ctttgcatgt cagaagttat tgctaacgat ccagcagtag ctccacactt
     9541 gcaagtagtt atggttgaaa actacaacgt tactgcagca agtttcctta tcccagcatg
     9601 tgatatctca gaacaaatct cacttgcttc taaagaagct tcaggtactg gtaacatgaa
     9661 attcatgttg aacggagctt tgacacttgg tactatggac ggtgctaacg tggaaatcgc
     9721 tgagttggtt ggagaagaaa acatctacat cttcggtgaa gattcagaaa ctgttatcga
     9781 cctttacgca aaagcagctt acaaatcaag cgaattctac gctcgtgaag ctatcaaacc
     9841 attggttgac ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga
     9901 acgtctttac aatgaattga tcaacaaaga ctggttcatg actcttcttg atttggaaga
     9961 ctacatcaaa gtcaaagagc aaatgcttgc tgactacgag gaccgtgacg catggttgga
    10021 taaagtcatc gttaacattt ctaaagcagg attcttctca tctgaccgta caatcgctca
    10081 gtataatgaa gacatctggc acttgaacta atactcttcg aaaatctctt caaaccacgt
    10141 cagctttatc tgcaacctca aagcggtgct ttgagcaacc tgcggctagc ttcctagttt
    10201 actctttggt tttcattgag tataagatac aaatttatac taatacattt tgtaaaaaag
    10261 cgagtttcga ttgaaattcg cttttttaaa tgctgtggat ttgggtcaat cttgtctaaa
    10321 aatagggaaa tcctagatac agtgaaggct ttaaatgctg gtttttactg tcttcagcct
    10381 tatatttttt cgtagttggt tacctcataa ctcttgtatt cgcttacata aagtattata
    10441 atataattgt aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat
    10501 tacctttctt gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg
    10561 gaaaatagtt tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat
    10621 tttaagaatg tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc
    10681 tatttatcca agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct
    10741 tcgatttcgg catgtttttt ctcgagttca gaacaacttg catcattgct aaattctttt
    10801 cgccatcagg agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa
    10861 gcaggaattt tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt
    10921 atcaaagcgc caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta
    10981 taagatcatt ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc
    11041 gtcattgcaa tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag
    11101 aatataaaca acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa
    11161 agttaatcct tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag
    11221 tccccggtga taataaattc atagcgaatt ctaaagcaac atcatttaca aaccaactac
    11281 ctagatatct agaaattgct gaacgaatag cactttttgc tacatgtttt ccttttactt
    11341 taattagatt tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gcagtatcta
    11401 atagagcacc catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg
    11461 taggtgggat tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt
    11521 gtgagacgtc tggatgaaaa gattggattt cgtttgcaag tgtattgatt tgttcttctg
    11581 ttagagaagt gacaggttga agttccatat ttgtttcaat ttgtgatact tgttcagaag
    11641 cgtatacagc tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa
    11701 ccgaaataaa tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta
    11761 cattttatca tatactgtta ttatagtcaa aaaaatattt ttcaaaatat aaatggacgg
    11821 atttattttg gattttattt gttattttga cctgcctcta tattggtaac catgatttgt
    11881 ttactctcaa tcatcaagaa ttctcttttc gtggtagcgt ttggggtctg gtactggcct
    11941 tatatcactt attgttcatt gataagtttg taatttcgaa tcgaaaataa agattagaac
    12001 tatgattgac tggctacttt taatattgat tttggaggaa gattttgtct ctattattta
    12061 ttattttaaa tttatttatt ttgtataaga tctattcttt gaggcgggaa aaatcgaaat
    12121 acttgattta tacggcctat atcatatttg gggtaaatgt agtatatggt attcaatggt
    12181 tattaagaga actgatttca aatatttccc cttaatgtgt atggaaacta taacaaaacg
    12241 cataagatta aggtttgtgt acctgttctt atacgttttt gtcatattga agattttcgg
    12301 taagttttct acttttgcga agtctagttt atactcaatg aaaatcaaag agtaaactag
    12361 ccgtaggttg ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa
    12421 aacatggttt tgaggttgta gatgaaactg acgaagtcag taaccatacg tacggcaagg
    12481 cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc tctgcttcga
    12541 tggtaatctc tgtcagtttg ctccagtcaa ttttgctctg gtcaacgtga aagaggagag
    12601 gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag
    12661 tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat
    12721 actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag
    12781 ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt
    12841 tggcaggtga gaagatatca agcagaatat ccatgttagc gtcttttata ggaagtcgtg
    12901 ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga
    12961 ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt
    13021 tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc
    13081 ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt
    13141 gttgacggtt ttgaaaattt tccttgtcat agttagcaga ttgcttgatt tgaggtgcta
    13201 gattgacata gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag
    13261 tctctaacag agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa
    13321 aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa
    13381 tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac taattctcca
    13441 atttatagaa tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa
    13501 taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt
    13561 tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa
    13621 aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg
    13681 tttctgtcgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc
    13741 aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg
    13801 ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt
    13861 caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac
    13921 atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca
    13981 gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt
    14041 cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt
    14101 cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat
    14161 attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt
    14221 tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt
    14281 atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta
    14341 gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga tacagttgtt
    14401 agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa
    14461 attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca
    14521 ggagagagtt ttccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta
    14581 gaaactggag agttacgcat ttgtgtaaca gataatcaga tgaacagccg tattttacag
    14641 ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc
    14701 aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg
    14761 acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa
    14821 atctctactc ctgtagctta tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg
    14881 attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag
    14941 acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat
    15001 agtgaggaag atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt
    15061 gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg
    15121 aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca accagttctt
    15181 attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct
    15241 ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg
    15301 attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa
    15361 cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat taggacagag
    15421 gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa
    15481 tttgagttag tagagaaact gcagaaagca ggtcacacta ttttgatggt tggagatgga
    15541 ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca
    15601 gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa
    15661 gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat tcaggatacc
    15721 gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag tccttcaaat
    15781 ctctctatct tacataatct aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa
    15841 aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag gttaactcct
    15901 ttgtttatag ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca
    15961 cgacggataa cagtcagttc attttctaac ttatcagcgt cactcaagac atagtcaagg
    16021 tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg
    16081 cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct
    16141 gcctgtactt ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg
    16201 tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct
    16261 tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt
    16321 ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag
    16381 attttcaaga agcgaacagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg
    16441 tatggagaag tcttttcggg attgagccag acggcatttc cttctgattt accaaatttc
    16501 ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcctta
    16561 cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga
    16621 agagtgacat tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa
    16681 gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc cttactcatc
    16741 atgtagttga ccgtgaagta ttttccaata tcacggagga agtcaatgaa gctgatgctg
    16801 ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga
    16861 aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg
    16921 agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg
    16981 agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg
    17041 tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct
    17101 tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgctct
    17161 tttagctcat caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct
    17221 attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt
    17281 gaaaatttcc cttttgtggt ataatagata gagtgaggaa atccatgcaa aatcaattaa
    17341 atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag
    17401 ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca
    17461 ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt
    17521 ttctaggagg aatgttggga gttgggattg ctttggggta cggagtggcc ttatttgaca
    17581 aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt
    17641 cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca
    17701 cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag
    17761 atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg
    17821 ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta
    17881 aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg
    17941 ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg
    18001 ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg
    18061 gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac
    18121 ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg
    18181 aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag
    18241 gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt
    18301 taccatcggg cacggttaca ggaatttcac gagactattt atactttaca actttggcag
    18361 aagctcaaga acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt
    18421 tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg
    18481 gtggttataa gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg
    18541 ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct
    18601 tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa
    18661 atcaaaataa tcatgccttt gataccaaac gttcgccagc ttctactacc aagcccttgc
    18721 tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact
    18781 atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa
    18841 tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc
    18901 gtatgctccg tgaaaagggt gttgatgtca agggttatat ggaaaagatg ggttacgaga
    18961 ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc
    19021 agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga
    19081 tttcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc
    19141 aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatcct
    19201 ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg
    19261 cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt
    19321 cgacacctag attaacccta ggtggctgga ttgggcatga tgataatcat tcattgtcac
    19381 gtagagcagg ttattctaat aactctaatt acatggctca tctggtaaat gcgattcagc
    19441 aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat
    19501 cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag
    19561 tagaggtcac aggttcgact gttaccagct attgggctaa taagtcagga gcgccagcga
    19621 caagttatcg ctttgctatt ggcggaagtg atgcggatta tcagaatgct tggtctagta
    19681 ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata
    19741 gcagtaactc aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat
    19801 gaagtggcca atcaatggat tgccactttt ttcctttcgt gttacaataa gggtatgaat
    19861 cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg
    19921 ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg
    19981 attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa
    20041 ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc
    20101 tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca
    20161 aatgctacga cagcaactat tttacagttt attagccctg tttttatcct cttttacaat
    20221 cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg
    20281 ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat gacgccgcta
    20341 gctcttataa caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa
    20401 ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt
    20461 ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt
    20521 atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg
    20581 aaggctgtgt ccttggtttc tcctttggtg gttgccgtta tcagtgccag tgaacctctc
    20641 tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta
    20701 gctatagcct tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt
    20761 agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac
    20821 ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc ttttaccgac
    20881 agcacgtttt atctcacatc cctaaaaaat catacctaaa aacagacaaa aaggtttcaa
    20941 atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac
    21001 tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac
    21061 cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa
    21121 actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt
    21181 agaaaatcaa gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga
    21241 taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aggtggaaat
    21301 tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc
    21361 tggaaccatg attgacatgg gtgccatcct tggtggccgt gctatcgttg gaaaaaatag
    21421 ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt
    21481 ccgtgtcgga gacaatgttc ttatcggtgc taatgcagtg gttatcgaag gagtccaaat
    21541 cggtagtggt tcagttgtcg ctgcaggagc tatcgttacc caagatgtcc cagaaaacgt
    21601 ggtagtagca ggtgttccag ctcgtatcat caaagaaatt gatgcccaaa cccaacaaaa
    21661 aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac
    21721 cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga
    21781 ctagacgagc tttacaccag attccagaga ttggcttgga ggagttcaag actcaggctt
    21841 atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt
    21901 ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc
    21961 ggacagatat tgatggtctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac
    22021 accaaggtcg catgcatgcc tgtggccatg attttcatat gaccattgcc ttaggctgtc
    22081 ttgagcgcgc ccttgaggag caacccaaga ataatctgct ctttctattt cagcctgctg
    22141 aagaaaatga agctggtggt atgctcatgt atgaggacgg tgcttttgga gattggttgc
    22201 caaaccaatt ctatggtctc catgttcgtc cagatttgaa agtcggccag attgcgacta
    22261 atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg
    22321 gccacgcagc ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga
    22381 cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct
    22441 tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg
    22501 gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag
    22561 ttgcagaagg ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg
    22621 gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac ttctttgacg
    22681 aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt
    22741 atctcctttc aaaggttgat ggcgtgatgt tttggctagg tatcgatagt ccctacgctc
    22801 ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt
    22861 ctagtttcct gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg
    22921 caagcaagtc ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg ctatagacca
    22981 agctttaacc gagcgaattt tacaacaccc cttttatcaa gaagccaagg tcatcgcaac
    23041 ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga
    23101 cggcaagaag gttttaatac ccaaaactta tcccaagggg cgcatggact ttgtagtcta
    23161 tgatccgcag cagttggtaa aaactgcctt tgccttactg gagccacagg gagatttgga
    23221 agtggtggat gtatctcaga ttgatttgat tcatgttcct ggcctggctt ttacgacgga
    23281 tggatatcgg attggatatg gtggaggtta ttatgaccgc tatctggaac atttttctgg
    23341 tcatactttg agtacggttc atccttgtca aattcaggac tttatacctg aaaaccatga
    23401 tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga
    23461 cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg
    23521 gaaactttga cagggcagat acattatttc gatttggagc catgtatggg ccagctattc
    23581 gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg
    23641 aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt
    23701 tcggctctaa gcagttcttt tttctctatc tcttatcagg aatgatgggc aatctctttg
    23761 tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat
    23821 ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc
    23881 aatcctatct gacacttttt gtggttaaca ttattggaag tgttctgatt ccaggaatca
    23941 gcctagcagg ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt atctttccag
    24001 ttagaggaga aaaacggatg tataatacca gccagagatt aggagcggta gtcttgttcg
    24061 taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa
    24121 tttgtgtaat gaaaaaagat aaggcatttt ttgaacctta tctttttatt ttattccttc
    24181 tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt gacttgtggg
    24241 tgtttgaggg cgtagtcaat agatgttttc ataaagccaa acttatcccc aacgtcgtaa
    24301 cgagctcctg taaattcacg ggcaaaaaca cgctgtgttt tattaagagt atcgattgca
    24361 tcagtaagtt ggatttcatt tccagcacca ggagcttgct tttcgagaat ctcaaaaatt
    24421 tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc taggagcgtc ctctggagct
    24481 ggtttttcaa caaaggtttc aacactgtaa agaccatctt ttccttcgcc ttgcggagca
    24541 ataaccccgt aagcagatac ttcgtcatga gggactggca tgacagcgat agtagacgcg
    24601 tgggtacgct tgtagtcatc catgagttgt ttggtaagtg gaacagcctt ttcgtctgtg
    24661 atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac gaaagccttg
    24721 gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggataaa atgcagacgc
    24781 atgccagttg tttcatcaac tagcttcaaa agatctgttt tccctttttc tttgaggtta
    24841 tattccaatt cgaagtttga atcgaagtgg tcctcaatag aacgttttga tttaccagtg
    24901 acaactagaa tatcttcaat acctgatttg agagcctctt ccacgataaa ctggatagtt
    24961 ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg taaaaatcga
    25021 gttcctagtc cagcagcagg gataactgcc tttctaactt ttgatgtcat aaaaatcctt
    25081 tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat gatgtcataa
    25141 atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg tgtaatgggc
    25201 atatagactc caagttcttg ggctagttca taggctgctc gagtcgttga aattccttcg
    25261 attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc gagagcatct
    25321 ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc tcccacacca
    25381 gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg ggtgatttct
    25441 gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag accatgtaaa
    25501 gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac cccgataaca
    25561 tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac gtattgagct
    25621 gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat ggtctcttct
    25681 gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg aatttcttct
    25741 tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga tgcgtgcatg
    25801 atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg tgtcactttt
    25861 gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa gtcggtgtag
    25921 gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt atggtgtgta
    25981 ttaatttcat tgatttgctc gggaagattt ccccaaatac gtatctcgtg tccattgtca
    26041 tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc gacggtttgt
    26101 ttttccatga tttcctcctt gatagatttc tttctcttat tctatcatat tctaggggat
    26161 tttgcacttg cattactggg gtatggtgga aaaatacaca aaaaccgaga cgaagggata
    26221 aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat tcagtatatg
    26281 cttataatag aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt tggcaaaaaa
    26341 attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg tgatgagtct
    26401 gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc aatactaaca
    26461 aagttaaaat atattgctga acgtttgggg gttgaagatt acaagttgat gccaagttat
    26521 atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggat tcctacatac
    26581 gaagatgaaa ctatcgccca aaagaaagag agtgttttga taagattttt gaagagtatt
    26641 atgataggtt acctgaggaa gaaagattta tcatcccaaa ttattcatat ctggcactaa
    26701 cgaactacac agttcaaaaa ttaccagaaa agctagttga aatactgtcc ttctggtgat
    26761 tttgcttaat ttctgatgtt cgagacataa ttgaggagat ttgtcttgat tttttcctaa
    26821 aaaagggcag actcctccct tggtttgatg ctcgattttt aaaataaggt gacttattct
    26881 gttaggcatg ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc
    26941 tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag acttgagaat
    27001 ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt
    27061 cgaaaacgct tgatagtcaa ggactttact tcatcaccag ctagctgctt taaaaagagg
    27121 tagagattat aagccagaca gcccatcatc atacgtactt cattcttaat catggtcgaa
    27181 ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc
    27241 cctcgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa attggtcaaa
    27301 ttggtcaaat gaactttttt acaaccataa aaaagagcac ttaatcgtac tcttctcttt
    27361 taaggattag ttgaattaat tcaaatccac tagttctcct gtttctaggt agactaggcg
    27421 ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga tgccctatga tataaaggta
    27481 ttgagttcca ttgggaattg aggtttcttg gtctttcata agtccaatga tttcctttga
    27541 taaggcataa taatattggt caatctgttc atctttttga gcaatactaa tagcttttga
    27601 ggcttggtgc aaaggaaagg caaccaataa atcggctagc atgttgaggg ataatttacc
    27661 catttggtgt aactgttctt cgtcaggggc tagttgattt tcttttagtt gcaaaacagc
    27721 tttggcaatg cctgccatat ggtctcccat acgttcaagg tctgaacaag aagacatgat
    27781 gctaatcaca aatcgaaggt cagacacttg tggctgctgc aaggccaaca aacgggcaca
    27841 ggtcaattcg atagcgcttt gaccttggtt gatagcatga tccttattga taattagctc
    27901 tgccatctcc ttgtctttgg aggctaaggc cagtaaggct tttgaagctg tttcaaggac
    27961 aagttgccct agtcctaaaa aggattgttc taattcatgc aattctaagt caaattgatt
    28021 tctcataggt ttttccttcc ttatccgaac cgtcctgaaa tatagtcttc tgtgcgctga
    28081 tcttttggat tggtaaacac gtcaacggta tctccaaatt cgcaaatttc tcctgttaag
    28141 aaaaaagcag ttttatctga aatacgtgaa gcttgttgca tgttatgggt aacaatgata
    28201 atcgtataat ccttttttag ttgctgaatg aggtcttcaa tttttaaagt ggagataggg
    28261 tctaaggctg aagtcggctc atccattaac agaacatcag gttctactgc taaagctcgc
    28321 gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca tggcactctt tttaagatca
    28381 tctttgactt cttcccaaat ggctgcccct tttaaagatt tctccactaa ggcatctaat
    28441 tgttttttgt ctcgaatacc atgtgtcctt ggaccataag ccacgttatc atagatagac
    28501 atggcaaagg gattaggctg ttgaaaaacc atccctacac gcttgcgtag ctgattaagg
    28561 ttgaatttgc tactataaat atcttgctca tctaagagga cttggccttc aatatggcaa
    28621 gaaggaacca aatcgttcat ccgattaagg gtttttagaa aagttgattt gccacaacca
    28681 gatgggccta tcaaggcagt aatctgtctt tctggtaatt gaatcgaaat attttttaag
    28741 gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg aaaatgttcc catactagga
    28801 agctcctttc acaagtttcc gagataataa gcttgataga gtatttatca ttaaaacagt
    28861 aataatcaaa atcacgccgg tagcataggc ttcattgaca tgtagcccct cacttgacag
    28921 catatacata tgtagggcta gagaacggcc tgaagacatg agactacttg gcgtattggt
    28981 agaggtacct aatgtataca tgagggcagc tgtttcacca acgatacggc caatagctag
    29041 tatcactcca gctaaaatac ctggcatggc aactggtaga acaattctaa aaacagtccg
    29101 taacttacct gccccaagtc cataacttgc ttgacgcatg ctatcactaa cagataaaag
    29161 ggcttcttct gttgagcgaa taatgactgg caacaccatg ataactgagg ttaagattcc
    29221 tgataacaga gagtattgaa aacctaagaa gactacaaag aagagcatgc caaacagacc
    29281 aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc aatcgcatga ttttaacaca
    29341 aagggaatct ttttttgtat attccacaag ataaaaacca gcaaaaatcc ctatgggcaa
    29401 ggctaaaaga agagcaccaa aaaccagaat aacggtggaa ataatcgctg gcataaggga
    29461 aatgttctca gaagtataag tccaagaaaa gagggataga cttagatgag gtaagccttt
    29521 gatgaggata aaaccaatga ttaaaaagag agagccaaag gttaaagctg aaaaacaata
    29581 aacgagaagt tttagcaggt atttactcat aagatgattt tcctttcaag taggcaaagt
    29641 aggcattaat caagagaata aggaaaaaga gaactgctga ggttgcaata agggcttccc
    29701 tatgctgacc tgatgcgtaa gccatttcca gaacaatatt ggttgttaag gttctggttc
    29761 ctgaaaagag tccacttgga ataatcggct ggttgcctgc caccaaaata actgccatgg
    29821 tttcacctac tgcgcgacca attcctaaaa taactgctga taaaatacca gatctcgcag
    29881 ctggcaagat gacactaaaa atactccgtt catgactagc tcctagagcc aagctaccag
    29941 aataatacgt tttgggaact gttcggatag cagattctga caaactgata atggttggca
    30001 aaatcattat tcctaatagt aacgaagcgg ttaggacact catgccattt cctaaaaagc
    30061 ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc ataaacaata gatggaatgg
    30121 ccgccatcaa gttgatagct gattttaaga agccatagac gggctttgga caataataaa
    30181 ccataaacac tgatgtcaag atgcctgttg gcaccccaat cacaatcgct cctaaggtaa
    30241 ttaataagga accaacgatc attggtaaaa taccatagct tgccggaatg ttcgttggcg
    30301 accaatcact gcctaataaa aaacgggcaa agccgtagtt agccatgaaa ggtaagccat
    30361 tactaaaaat aaagaaacag attagcaaaa tagctacaac agctactgtt gcactcatga
    30421 aaaaaattgc cctaaaaact gcttctttga aggcttgttt tgtcacatct tgtcctttct
    30481 agtgaagaaa gtaagggaga tacgacacct ccctacttgc cttctttatc ttattgtacg
    30541 atgaaacgtc tgcatctctt tagagattta tggagcaaac attttattta atcttgtccc
    30601 aggtggttaa tttgccacta aaaacgtctg caagttcagc catactgact tggcttgcct
    30661 tattgtcatt attgaccaca acagcaatac cgtctaaagc aatagcatca tgggtgagac
    30721 tcttaccttc ttcaggagtt aattccctag aaaccatacc aatatcagcg gttttctcct
    30781 taacagcggt aatacctgct gaagacccat tagaggtaat atcaatcgta acttctggat
    30841 tttctttttt ataagcttct gctaattttt ccattaaaga agatactgaa gtggaaccta
    30901 caacagacaa cttgcctgat aagtgttggc ttgtatattc tgtggtttcg gttttagctt
    30961 caataaattt attatctgtg accacttgtt gaccttgttt ggagtggata aagctgataa
    31021 aatcttgacc tagcttggaa agattagaag accaaacaat gttgaaggga cgttgaagag
    31081 ggtattcacc atctaaaact gtgtctcgac tagccttgac accatcaatc tctaaagcct
    31141 tgacagattt cgttaaagat cccaaggaga tgtagccgat agcattagca ttcccttgaa
    31201 ctgctgagag aacaccttct gtactatttt gaatcacagc tgttttggca gtgttgtcaa
    31261 tttttttatc accgtctttt ttgagaatcc ctgtgatttc tgtgaaggca ccccgtgttc
    31321 cagagccatt ttctcgtgaa atcacctcaa tcgttcctga agctgactgt ttggaagcag
    31381 ctgactgatt gccacaggca acaagcccaa atcctgataa gccaatggct gcaagagtaa
    31441 gcattttttt gaatttcata ataatcacct ttatctctat gtatttttct tgtgtaggct
    31501 tactacattt atagtctaac aagtctttgt aaaggtttat ccctgattca tgtaaagatt
    31561 gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg ctcctaaaaa tagctttaaa
    31621 aattattagt cctgtgcgaa agattggtta ggaagaaaaa tcgtgaagca actgcctctg
    31681 ccaagctgac tcgtcaccgt gacttggcca cctaataatt gactgagttc tttgacaatg
    31741 gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac ctttattaac tcggtaaaaa
    31801 cgttcaaaaa tacgatcctg ctctaattga ctaataccaa tccctgtatc tgatacagaa
    31861 atcttaatgc cttcgttccc cttttgggtc ttgacctcaa tttttccccc ttgttcagtg
    31921 taacggatgg cattggataa aagattgagt aagatttggg aaagtaattg actatctgat
    31981 acgagggtga catcatctgg cacctgcacc tttagctgta aatccttctt cttgagctga
    32041 ggttgcaagc tttgagtcaa atcctgtaca aattctgcca aagaaagggt cgtccattgt
    32101 ataggcattt gttgagcctt agataaggta agaagatgct caacaatatg ctcaagacgc
    32161 aaactttctt tgtaaataat gtctagaaag tcatccttga gcgcttcttc ttcagctgac
    32221 atccccttaa tggtttcagc aaagccctta atcgaagtaa ctggtgtcct caattcatgg
    32281 gaggcatttg agacaaaggc taaatttaac ttttcataag ttctaatcgt tgttaaatca
    32341 tatagcaaga cgagcacagc ttccacagat tgggtggggc taaaaacggg aactgctgtc
    32401 acttctaaaa tcaagtcacc ctcatgaaac ccacttactt cttgttttaa ccttgttttt
    32461 tgatcaaagg cttggtgaac taaatttcga atatccatcc gtttgaggtc atcaagtgaa
    32521 cttatgtcgc cgtccacatc gggaaaataa tgaggcagag agcgactgga taataacatc
    32581 tgaccttgag cggaaactaa aaacgtcccc atggttaggt gcgacagaag aacctccatt
    32641 gtttcggcta gatccttgta ttgctgatcc tgttgggaga ctttggtttt taggccagac
    32701 acatactgag ccaaagactt taagtcttct tgcccttttt ctaaaaagta ttcactactg
    32761 gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc atttccaaag gcaaaagagc
    32821 cagtagccac ctagtcccaa agaaagggct agaagaaaga gaccgatgcc tttactgatc
    32881 caagttaatg ccatccctgc aatcagaatg aggctaacac ttagattgac tagccaaaat
    32941 tgaaggtagc gtttcatcta taactccttg aacttataac cataaccccg aatggttcga
    33001 ataaattgag gggctttagg attgtcttca attttttccc tcaacttacc aatatgaacg
    33061 tccaccaaac gtgtttcctg cccaaagtca tacccccaga tacgttccaa aagacgctct
    33121 ctagtcagtg tcatgttggg atgtttcata agatagagca agagttcaaa ttcttttggg
    33181 gtcaaactca gtaacttatt cgccttgtag acttcatgac gctcagggta tactttcaag
    33241 gtcccaaata gccaagaatc gtcagcgata ttatctgaat catctccttc ttgttctcct
    33301 ttagttcgcc tgaggacagc cttgacacgc gccagcaatt ctctagggct aaaaggcttg
    33361 gtcaggtagt catcagcccc taattccaag gccaaaacct tatcaaattc atcacttttc
    33421 gcagaaacca tcataattgg agttttgacg cctttggctc tcagccgctt acaaacttcc
    33481 atgccatcta attgtggtaa catgatatca agcaagataa aatcaaaggg ttctgtttct
    33541 gccaaagcta aggccttccg tccatttgtc accaattgag tagaaaagcc ttccttactt
    33601 aaatggtagt caagcaattt cagaatgtgt tcttcatcat ccactaataa gacttgtttt
    33661 gtcatctatt atctcctatt ggtaacatta taacacaatt atcagaaatc ctaacattgc
    33721 taaatcagat taaatttgcc tatcaagact agtatctggt caaacgctca atcatctcct
    33781 tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa taattcaaaa tcctcaaatt
    33841 caaaaccagg agcaacaaga caagaaacca gagcatcatc cttatcaact gttgatcccc
    33901 aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc tttggatatg tccaggccta
    33961 aagtgactgc ttcgtagtga ccatctgctg taatcatgtg aacagtaagt ggggatcctg
    34021 catgaaaata ccagatttca tctgctgtca atcggtgaaa atgtgaagga ttcgtttctt
    34081 ctaataagaa ataaatactg gtataaagcg cccttccctt accagcaagg tttatagtgt
    34141 ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac atggggagct aactctagag
    34201 ttcttatcaa gtcttcttt
//
LOCUS       DBEJJE010000020        33807 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEJJE010000020 DBEJJE010000000
VERSION     DBEJJE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.20"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            217..447
                     /gene="blpU"
                     /locus_tag="ACL3F5_000963"
                     /pseudo
     CDS             217..447
                     /gene="blpU"
                     /locus_tag="ACL3F5_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            450..575
                     /locus_tag="ACL3F5_000964"
     CDS             450..575
                     /locus_tag="ACL3F5_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0514790.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1162..3315
                     /gene="comA"
                     /locus_tag="ACL3F5_000965"
     CDS             1162..3315
                     /gene="comA"
                     /locus_tag="ACL3F5_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0514791.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQHGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLIVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3328..4677
                     /gene="comB"
                     /locus_tag="ACL3F5_000966"
     CDS             3328..4677
                     /gene="comB"
                     /locus_tag="ACL3F5_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0514792.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4847..5554
                     /gene="purC"
                     /locus_tag="ACL3F5_000967"
     CDS             4847..5554
                     /gene="purC"
                     /locus_tag="ACL3F5_000967"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0514793.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5556..5699
                     /locus_tag="ACL3F5_000968"
     CDS             5556..5699
                     /locus_tag="ACL3F5_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0514794.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5756..9481
                     /locus_tag="ACL3F5_000969"
     CDS             5756..9481
                     /locus_tag="ACL3F5_000969"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0514795.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9574..11016
                     /gene="purF"
                     /locus_tag="ACL3F5_000970"
     CDS             9574..11016
                     /gene="purF"
                     /locus_tag="ACL3F5_000970"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0514796.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11053..12075
                     /gene="purM"
                     /locus_tag="ACL3F5_000971"
     CDS             11053..12075
                     /gene="purM"
                     /locus_tag="ACL3F5_000971"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0514797.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12072..12617
                     /gene="purN"
                     /locus_tag="ACL3F5_000972"
     CDS             12072..12617
                     /gene="purN"
                     /locus_tag="ACL3F5_000972"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0514798.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFAFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12701..13194
                     /locus_tag="ACL3F5_000973"
                     /pseudo
     CDS             12701..13194
                     /locus_tag="ACL3F5_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            13219..14766
                     /gene="purH"
                     /locus_tag="ACL3F5_000974"
     CDS             13219..14766
                     /gene="purH"
                     /locus_tag="ACL3F5_000974"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0514799.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKASPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14888..16150
                     /gene="purD"
                     /locus_tag="ACL3F5_000975"
     CDS             14888..16150
                     /gene="purD"
                     /locus_tag="ACL3F5_000975"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0514800.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVKKVFVVPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGIPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHDMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDGKEPNITWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16407..16523
                     /locus_tag="ACL3F5_000976"
     CDS             16407..16523
                     /locus_tag="ACL3F5_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0514801.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16553..17041
                     /gene="purE"
                     /locus_tag="ACL3F5_000977"
     CDS             16553..17041
                     /gene="purE"
                     /locus_tag="ACL3F5_000977"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0514802.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17028..18119
                     /gene="purK"
                     /locus_tag="ACL3F5_000978"
     CDS             17028..18119
                     /gene="purK"
                     /locus_tag="ACL3F5_000978"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0514803.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDTVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18129..18356
                     /locus_tag="ACL3F5_000979"
     CDS             18129..18356
                     /locus_tag="ACL3F5_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0514804.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18419..19717
                     /gene="purB"
                     /locus_tag="ACL3F5_000980"
     CDS             18419..19717
                     /gene="purB"
                     /locus_tag="ACL3F5_000980"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0514805.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19772..23710)
                     /gene="strH"
                     /locus_tag="ACL3F5_000981"
     CDS             complement(19772..23710)
                     /gene="strH"
                     /locus_tag="ACL3F5_000981"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0514806.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGDYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERELQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDHFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24024..24740)
                     /locus_tag="ACL3F5_000982"
     CDS             complement(24024..24740)
                     /locus_tag="ACL3F5_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0514807.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25088..26875
                     /locus_tag="ACL3F5_000983"
     CDS             25088..26875
                     /locus_tag="ACL3F5_000983"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0514808.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26872..27348
                     /locus_tag="ACL3F5_000984"
     CDS             26872..27348
                     /locus_tag="ACL3F5_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0514809.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27376..28281
                     /locus_tag="ACL3F5_000985"
     CDS             27376..28281
                     /locus_tag="ACL3F5_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0514810.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28268..29083
                     /locus_tag="ACL3F5_000986"
     CDS             28268..29083
                     /locus_tag="ACL3F5_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0514811.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29090..29494
                     /locus_tag="ACL3F5_000987"
     CDS             29090..29494
                     /locus_tag="ACL3F5_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0514812.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29747..30913
                     /locus_tag="ACL3F5_000988"
     CDS             29747..30913
                     /locus_tag="ACL3F5_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0514813.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVSLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31029..32066
                     /locus_tag="ACL3F5_000989"
     CDS             31029..32066
                     /locus_tag="ACL3F5_000989"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0514814.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32274..33128
                     /locus_tag="ACL3F5_000990"
     CDS             32274..33128
                     /locus_tag="ACL3F5_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0514815.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33278..33535
                     /locus_tag="ACL3F5_000991"
     CDS             33278..33535
                     /locus_tag="ACL3F5_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGR0514816.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33577..>33807)
                     /locus_tag="ACL3F5_000992"
     CDS             complement(33577..>33807)
                     /locus_tag="ACL3F5_000992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514817.1"
                     /translation="NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKS
                     NFLGSVHSTPDTMRFFNFKDFLQLLLTHIKLF"
BASE COUNT         9399 a         6554 c         7930 g         9924 t
ORIGIN      
        1 aactaggatt ctagttttgc aggaagtcta atagtaaaaa agtgattaga aaacatcttt
       61 tttaaaaata gagatgattt tgaaacaaaa aagctaattc aagacgtttc gatgccaatt
      121 caagatttgg atgaaaaaaa ttaatagata ctgttatact aaacttgtca agtttgtaac
      181 aagacaaata ttaaaaataa aaaagaggta ttcgttatga atacaaaaaa gatgtcacaa
      241 tttgaaatta tggatactga gatgcttgct tgagttgaag gtggcggatg caattgggga
      301 gattttgcca aagcaggtgt tggaggagga gcagcacgag gtcttcagct aggaattaaa
      361 acaagaacat ggcaaggtgc agcaactggt gctgcgggag gagctatact tggaggtgtg
      421 gcctatgcag cgacatgttg gtggtaatta tggattttaa aagttttatt attggtttag
      481 tagttggtat atttggtcct tatatggatg atttaattag aaaaaaattt ttaaagtctt
      541 cggagaagaa aacagaaaaa tctgttaaaa aataatcaaa actataaatg atgaatctga
      601 atcaaaatta ttttgcgcat gtaaagagga gtcttatagt aacgagtcaa aaaaggagta
      661 actatgaatc gtaatttaga acggtgttat ctattctgac taggaataga tcataccaga
      721 ggtagcttag aaatagcagg gacattagaa attgaagtaa taaataggat gtcgtaagtg
      781 ttactatcaa tgatttattt gtttcaagct tgcctagggt gacagtaaaa aatcaatttc
      841 ctttcaatag catattttta gtgggcagga ctcttgttct gcctattttt ttatccaaaa
      901 agtgcatttg ggagggagat aggcgcattt gggaaggaag tccagttttt gtttagtgat
      961 tggggtaaga tagttgttat cagatgagtt tatactcttc gaaaatcaaa ttcaaaccac
     1021 gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc agtcctatct acaacctcaa
     1081 aacagtgttt tgagcagctt gcggctagtt tcctagtttg ctctttgatt ttcattgagt
     1141 attagggaaa aggagatgaa tatgaaattt gggaaacgtc actatcgtcc gcaagtggat
     1201 cagatggact gcggtgtagc ttcattagcc atggtttttg gctactatgg tagttattat
     1261 tttttggctc acttgcgaga attggctaag acgaccatgg atgggacgac ggctttgggc
     1321 ttggtcaagg tggcagagga gattggtttt gagacgcgag ccattaaggc ggatatgacg
     1381 ctttttgact tgccggattt gacttttcct tttgttgccc atgtgcttaa ggaagggaaa
     1441 ttgctccact actatgtggt gactgggcag gataaggata gcattcatat tgccgaccca
     1501 gatcctgggg tgaaattgac caaactgcca cgtgagcgtt ttgcggaaga atggacagga
     1561 gtgactcttt ttatggcacc tagtccagac tacaagcctc ataaggaaca aaaaaatggt
     1621 ctgttctctt ttatccctat attagtgaag cagcatggct tgattgccaa tatcgttttg
     1681 gcaacactct tggtaaccgt gattaacatt gtgggttctt attatctgca gtctatcatt
     1741 gatacctatg tgccagatca gatgcgttcg acactaggga ttatttctat tgggctagtc
     1801 atcgtctaca tcctccagca aatcttgtct tacgctcagg agtatctctt gcttgttttg
     1861 gggcaacgct tgtcgattga cgtgattttg tcctatatca agcatgtttt tcacctccct
     1921 atgtccttct ttgcgacacg caggacaggg gagatcgtgt ctcgttttac agatgctaac
     1981 agtatcatcg atgcgctggc ttcgaccatc ctttcgattt tcctagatgt gtcaacggtt
     2041 gtcattattt cccttgttct attttcacaa aataccaatc tctttttcat gactttattg
     2101 gcgcttccta tctacacagt gattatcttt gcctttatga agccgtttga aaagatgaat
     2161 cgggatacca tggaagccaa tgcggttctg tcttcttcta tcattgagga catcaacggt
     2221 attgagacta tcaagtcctt gaccagtgaa agtcagcgtt accaaaaaat tgacaaggaa
     2281 tttgtggatt atctgaagaa atcctttacc tatagtcgag cagagagtca gcaaaaggct
     2341 ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc tctggatggg ggctgttctg
     2401 gtcatggatg gcaagatgag tttggggcag ttgattacct ataatacctt gctggtttac
     2461 tttaccaatc ctttggaaaa tatcatcaat ctgcaaacca agcttcagac agcgcaggtt
     2521 gccaataacc gtctaaatga agtgtatcta gtagcttctg agtttgagga gaagaaaaca
     2581 gttgaggatt tgagcttgat gaagggagat atgaccttca agcaggttca ttacaagtat
     2641 ggctatggtc gagacgtctt gtcggatatc aatttaatcg ttccccaagg gtctaaggtg
     2701 gcttttgtgg ggatttcagg gtcaggtaag acgactttgg ccaagatgat ggttaatttt
     2761 tacgacccaa gtcaagggga gattagtctg ggtggtgtca atctcaatca gattgataaa
     2821 aaagccctgc gccagtacat caactatctg cctcaacagc cctatgtctt taacggaacg
     2881 attttggaga atcttctttt gggagccaag gaggggacga cacaggaaga tatcttacgg
     2941 gcggtcgaat tggcagagat tcgagaggat atcgagcgca tgccactgaa ttaccagaca
     3001 gaattgactt cggatggggc agggatttca ggtggtcaac gtcagagaat cgctttggcg
     3061 cgtgctctct tgacagatgc gccggtcttg attttggatg aggcgactag cagtttggat
     3121 attttgacag agaagcggat tgtcgataat ctcatggctt tggacaagac cttgattttc
     3181 attgctcacc gcttgactat tgctgagcgg acagagaagg tagttgtctt ggatcagggc
     3241 aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac agggtggctt ttacgcccat
     3301 ttggtcaata gctagaaaga ggagaggatg aaaccagaat ttttagaaag tgcggagttt
     3361 tataatcgtc gttaccataa tttttccagt agtgtgattg tacccatggc ccttctgctc
     3421 gtgtttttac ttggctttgc aactgttgca gaaaaggaga tgagtttgtc cactagagct
     3481 actgtcgaac ctagtcgtat ccttgcaaat atccagtcaa ctagcaacaa tcgtattctt
     3541 gtcaatcatt tggaagaaaa taagctggtt aagaaggggg atcttttggt tcaataccaa
     3601 gaaggggcag agggtgtcca agcggagtcc tatgccagtc agttggacat gctaaaggat
     3661 caaaaaaagc aattggagta tctgcaaaag agcctgcaag aaggggagaa ccactttcca
     3721 gaggaggata agtttggcta ccaagccacc tttcgcgact acatcagtca agcaggcagt
     3781 cttagggcta gtacatcgca acaaaatgag accatcgcgt cccagaatgc agcagctagc
     3841 caaacccaag ccgaaatcgg caacctcatc agtcaaacag aggctaaaat tcgcgattac
     3901 cagacagtta agtcagctat tgaaacaggt gcttccttgg ccggtcagaa tctagcctac
     3961 tctctttacc agtcctataa gtctcagggc gaggaaaatc cccaaactaa ggttcaggca
     4021 gttgcacagg ttgaagcaca gatttctcag ttagaatcta gtcttgctac ttaccgtgtc
     4081 cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag ggttaagcag tcaattggaa
     4141 tcccttaaat cccaacactt ggcaaaggtt ggtcaggaat tgacccttct agcccagaaa
     4201 atcttggagg cagagtcagg taagaaggta cagggaaatc ttttagacaa ggggaaaatt
     4261 acggcgagtg aggatggggt gcttcatctt aatcctgaga ccagtgattc tagcatggtt
     4321 gcagaaggtg ccctactagc ccaactttat ccatctttgg aaagagaagg gaaagccaaa
     4381 ctcacagcct atctaagttc aaaagatgta gcaagaatca aggtcggtga ttctgttcgc
     4441 tatactacga ctcatgatgc cgggaatcaa cttttcctag attcaactat tacaagtatt
     4501 gatgcgacag ctactaagac tgagaaaggg aatttcttta aaatagaggc ggagactaat
     4561 ctaacttcgg agcaggctga aaaacttagg tacggggtgg aaggccgctt gcagatgatt
     4621 acgggcaaga aaagttatct acgttattat ttggatcaat ttttgaacaa agagtaatgt
     4681 tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa gattcttctt gcagtttttt
     4741 ctttacaatt tttgaaaaac atctactatt tattcggtta aattcttgtg ttttttggtt
     4801 ttttgtggta aaatgtgctc aagtaatacg aaaggcgaac tttaaaatgt caaaacaatt
     4861 gatctattcg ggaaaagcta aagatatcta tacaactgag gatgaaaatc ttattatttc
     4921 aacttacaag gaccaggcga ctgctttcaa cggtgtcaag aaggagcaga ttgcaggtaa
     4981 gggagtcttg aataatcaga tctcatcttt tatttttgag aaattaaatg cggctggtgt
     5041 ggcgactcac tttgtggaga aactttcaga cacggaacaa ctcaataaaa aggttaagat
     5101 tattcctttg gaagtcgtgc tccgcaacta tactgctggt tccttttcaa aacgttttgg
     5161 tgtggatgag ggaatcgcct tggagactcc gattgtcgaa ttttactaca aaaatgatga
     5221 tttggatgat ccatttatca atgatgagca tgtgaaattc ctacagattg cgggtgacca
     5281 gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat gaactattga aagtctggtt
     5341 tgctgagatt gggcttaaat tgattgactt taagctagag ttcggttttg acaaggatgg
     5401 caagattatc ttggcagacg aattttcacc agataactgc cgcttgtggg acgctgatgg
     5461 caaccacatg gataaggatg ttttccgtag aggattggga gaactaaccg acgtttatga
     5521 gattgtttgg gaaaagttgc aggaattgaa ataatctgtt tgcaacggaa aaccttcgtc
     5581 tctcaactaa aaggactcag gctgaaaagg tcccccagac cttttcactc tgtagagaac
     5641 taggtgaact aacagatgtt tacgaaattg tctgggaaaa gttgcagggt ttaaaataac
     5701 aacctcaagg ctgtttggga atattgcaag agctgaaata aaggaataag aattgatgga
     5761 taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc aagtcagaga gtttggttag
     5821 agagctccag cacaacttgg gactgtcaag cttgaaaagt attcgtattg tgcaagtata
     5881 tgatgtattt gacttggctg aggacttgtt tgcacctgca gagaagcaca ttttctctga
     5941 gcagggaacc gaccatgttt tagatgaagt atctgtgcag gcggatcttg ctaactatgc
     6001 tttctttgcc attgaaagtc tgccagggca gtttgaccag cgtgcagctt cgtcacagga
     6061 agccttgctt ttgttgggaa gttcgagtga cgtgacagtc aacacagccc aactttactt
     6121 ggtgaataaa gatattgatg cgactgagtt ggaagctgtc aaaaactacc tgctcaatcc
     6181 agttgattct cgtttcaagg atatcacgac agggattgcc aagcaggagt tttcagagtc
     6241 agacaagacc attccaaaat tgactttctt tgaaagctat acagcagaag actttgctcg
     6301 ctacaaggcc gagcaaggga tggccatgga agtggatgat ttgctcttta tccaagacta
     6361 ctttaagtca atcgggcgcg tgccaactga gactgaactc aaggttttgg acacttactg
     6421 gtctgaccac tgccgtcata cgacttttga gacagagttg aaacacatcg acttttcagc
     6481 ttctaaattt caaaagcaat tgcagtcaac ctatgacaag tatattgcca tgcgcgagga
     6541 gttaggtcgg tctgaaaaac cacaaacctt gatggatatg gcgactattt tcggtcgtta
     6601 tgagcgtgct aacggacgat tggatgatat ggaagtctct gacgaaatca atgcctgctc
     6661 agttgaaatt gaagtggatg ttgatggtgt caaggaacct tggctcctca tgtttaaaaa
     6721 tgaaacccac aaccatccaa cagaaattga gccatttggt ggagcggcta cctgtatcgg
     6781 tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt taccaagcca tgcgtatttc
     6841 aggtgctggt gatattacag caccgatttc ggaaactcgt gctgggaaat tgccacaaca
     6901 agtcatttct aaaacagcag ctcatggtta ttcttcatat ggtaaccaga ttgggcttgc
     6961 cacaacctac gttcgtgaat acttccaccc aggctttgta gctaaacgta tggaacttgg
     7021 tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt gaaaaacctg aagcaggtga
     7081 tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt gtcggtggtg cgacgggctc
     7141 ttctaaggtt caaacagttg agtctgtaga gactgctggt gctgaggttc aaaaaggaaa
     7201 tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat ggcaatgtca ctcgtctgat
     7261 caagaagtcc aatgactttg gggcaggcgg tgtctgtgtg gctatcggtg aattggcaga
     7321 cggtcttgaa atcgacctca acaaggtgcc tcttaaatac cagggcttga atggtacaga
     7381 aattgccatc tctgaatcac aagaacggat ggcggtcgtg gttcgtcctg aagatgtgga
     7441 taccttcgtt gccgaatgta acaaagaaaa tattgatgct gttgtggtgg cgacagtaac
     7501 tgaaaaacca aatcttgtca tgcactggaa tggtgagaca atcgttgact tggagcgtcg
     7561 tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc aaagttgtgg acaaggatgt
     7621 caaactccca gaagagcgtc aaacatctgc tgaaacactg gaatcagata cccttacggt
     7681 tctatctgac ctcaaccatg caagtcaaaa aggattacag actatctttg actgctctgt
     7741 tggacgctca acggttaatc acccacttgg tggtcgttac caactcacac caactgaggc
     7801 atctgtgcag aaattgccag ttcaacacgg tgtgactcat actgcgtcgg tcattgctca
     7861 aggtttcaac ccatatgtag ctgaatggtc tccataccac ggtgctgctt atgcggttat
     7921 cgaagcaact gctcgtttgg tggctgctgg tgccaactgg tctaaggctc gtttctctta
     7981 ccaagaatat ttcgagcgga tggacaagca agcagagcgt tttggtcagc cagtagccgc
     8041 ccttctaggc tctattgaag cacaaattca gcttggcttg ccatctatcg gtggtaagga
     8101 ctccatgtct ggtacctttg aagaattgac cgttccgcca accttggttg cctttggggt
     8161 gacgacggca gatagccgta aggtgctctc tccagaattt aaagctgttg gggaaaatat
     8221 ctactacatc ccaggtcaag ccctctctgc agagattgat tttgacttga ttaagaaaaa
     8281 ttttgctcag tttgaagcaa gccaagctga ccataaagtg acatctgcat cagctgtcaa
     8341 atacggtggt gtagttgaaa gtttggctct tgctaccttt ggaaactata ttggtgcaga
     8401 ggtgaccttg cctgaactta aaacagcttt gacagctcaa ttaggcggct ttgtcttcac
     8461 atctcctgaa gaaattgctg gagtagagaa gattggacaa acgaaagcag actttacact
     8521 gactgtcaac ggtgtgaagc tagatggaca caagcttgac agtgcatttc aagggacatt
     8581 ggaagaagtt tacccaacag aatttaccca agcgaaagaa ctagaagaag taccagctgt
     8641 ggtatcagat gttgtgatta aagccaaaga aaaggttgaa aaacctgtgg tttacattcc
     8701 agtctttcca ggaaccaact cagaatatga ttcagctaag gccttcgaaa aagaaggtgc
     8761 agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa gctattgtca agtcagttga
     8821 aactatggtt gacaatatcg acaagactaa tattctcttc tttgccggtg gattctcggc
     8881 tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat atcctgctta atgaaaaagt
     8941 gcgtgtggct attgatagct ttatcgcccg tggtggcttg attatcggta tttgtaatgg
     9001 attccaagcc ttagtcaaat cgggtctcct accatacgga aactttgaag atgctaacag
     9061 tactagtcca accctcttct acaatgatgc caaccaacac gtggccaaga tggtggaaac
     9121 tcgtattgcc aataccaact caccatggtt ggctggtgtg caagtgggcg atatccacgc
     9181 tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg gctgaggaat ttgcagagct
     9241 ccgtgacaat ggacaaattt tcagccaata cgttgacttt aacggtaaac caagtatgga
     9301 ttctaagtac aatccgaatg gttctgtcca tgccatcgaa ggaattacca gcaagaatgg
     9361 tcaaatcatc ggtaagatgg gccactcaga acgttatgag gatggtcttt tccaaaatat
     9421 cccaggcaat aaagaccaac acctgttcgc atcagcggtt aaacatttca ctggaaaata
     9481 agacttacag attttctaat agatagtatc agtaatgtaa aagtcatgta aatctagctc
     9541 ttgatgatta caaatgaaaa ttaggtataa aaaatgacat acgaagtaaa atctcttaat
     9601 gaagaatgtg gtgttttcgg tatttgggga catccagatg ctgctaagtt gacctatttt
     9661 ggactccaca gtcttcaaca ccgtggtcag gagggggcag gaatcctctc caatgatcaa
     9721 ggacaactga agcgccatcg tgacatgggg cttttatcag aagttttcag aaatccagcc
     9781 aatttggata aattgacagg agctggtgcg attgggcatg tgcgttatgc gactgctggc
     9841 gaagcttctg ttgataacat ccaacccttc ctcttccgtt ttcacgatat gcagtttggt
     9901 ttggctcata atggaaatct gaccaatgca gcctctctca agaaagaact ggaacaaaga
     9961 ggagcaattt tcagcgcgac ttcggactct gaaatcttgg ctcacctcat tcgtcgcagt
    10021 cataatccta gcctgatggg caaaatcaag gaagcgctca gtcttgtcaa aggtggtttt
    10081 gcctatatct tgctgtttga ggacaagttg attgcggctc ttgaccctaa tggctttcgt
    10141 ccgctttcta tcgggaaaat ggccaacgga gcggtggttg tttcctctga aacctgtgct
    10201 tttgaggtca ttggtgccga gtggatttgt gatttgaagc caggtgagat tgtgatcatt
    10261 gatgacgagg gcattcagta tgacagctat acagatgata cccagttggc gatttgttct
    10321 atggagtata tctactttgc ccgccctgat tctaatatcc acggtgtcaa tgtccatacg
    10381 gcacgtaaga gaatgggagc gcaattggcg cgagaattta agcatgaggc agatattgta
    10441 gttggtgtgc ccaattcttc cctaagcgcg gctatgggat ttgcggaaga atcaggctta
    10501 ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc gaacttttat ccaaccgact
    10561 caagaattgc gggagcaagg agtgcggatg aaactgtctg ctgtttcggg tgttgtcaaa
    10621 ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg gaacaacctc tcgtcgtatc
    10681 gttcagctct tgaaagaagc gggtgcgact gaggttcacg ttgccattgg aagtcctgca
    10741 ctagcgtatc catgtttcta cgggattgat atccagaccc gtcaggagct gattgcagcc
    10801 aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg acagtctgac ttatctttca
    10861 attgatggct tgattgagtc gattggtatc gaaacagatg cgccgaacgg tggtctctgt
    10921 gtcgcttact ttgacggtga ctacccaacg cctctctatg actacgaaga agactatcgt
    10981 agaagtttgg aagaaaagac cagtttttac aagtaggcga cagattctcc attaaagaaa
    11041 aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt cgggtgtgga tgttgaagcg
    11101 ggttatgaag ttgttgaacg gattaaaaag cacgtggccc gtacggagcg tgcaggtgtc
    11161 atgggagctc ttggtggctt tggtggtatg tttgaccttt ccaagactgg ggttaaagaa
    11221 cccgtcttga tttcagggac tgacggtgtc ggaaccaagc tcatgttggc tatcaagtac
    11281 gacaagcacg ataccatcgg gcaggactgt gtggccatgt gtgtcaacga catcattgct
    11341 gcaggtgcgg aacccctcta ttttctcgac tacgtagcga cagggaagaa tgaaccagct
    11401 aagctagaac aagtggttgc tggtgtggca gaaggttgtg tgcaggctgg tgctgccctc
    11461 atcggtgggg aaacggctga aatgccgggc atgtacggcg aagacgacta tgacttggct
    11521 ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg acggttcaaa ggtggtagag
    11581 ggagatgttc ttctcggact tgcttcaagt gggattcact caaatggtta ctctttggtt
    11641 cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac cagaattgga aggcaagaaa
    11701 cttaaggaag ttctacttga gccgactcgt atctatgtca aggctgtttt gccgctcatc
    11761 aaagaagagt tggtcaacgg cattgcccac atcacaggtg gtggctttat cgaaaatgtc
    11821 cctcgtatgt ttgcagatga cctagctgct gaaattgatg aaagcaaagt tccagtgctt
    11881 ccaattttca aagcccttga aaaatatggt cagattaaac acgaagaaat gtttgaaatc
    11941 ttcaatatgg gtgtgggact tatgttggcg gtcagccctg aaaatgtaga gcgtgtaaaa
    12001 gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg tcaagaaaga aaacgaaagt
    12061 gtcattatca aatgaaaaaa atagcggttt ttgcctctgg taatggctca aattttcagg
    12121 tgattgccga agaatttcca gtggagtttg ccttttcaga ccatcgtgat gcctatgtgc
    12181 ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt tgaactcaag gagtttgaga
    12241 gcaaggcaga ctacgaagca gcccttgtcg aactcttgga agaacaccag attgacttgg
    12301 tttgcctagc aggctacatg aaaatcgttg gaccaacctt attgtcggct tatgaaggtc
    12361 ggattgtcaa cattcatcca gcctacttgc cagaatttcc aggagctcat gggattgagg
    12421 atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat tcactgggtg gattcgggtg
    12481 tggatacagg ccaggtcatc aaacaggttc gtgtgccacg actagctgat gataccattg
    12541 acagatttga agctcgcatc catgaagcag agtacaggtt gtatccggaa gtagtgaagg
    12601 ctctatttac agattgactt tttgatgatt catatgatat ctttgatttt aaattggagt
    12661 cagtgtttgt tgaagacggc ttcaaactga ggtatttgta atgttagaat ctaaaaaaac
    12721 aactcgatat gtattttatg tctatctgat gttattaact tggggaatct tatttaagtt
    12781 tgaaacaaat cctgaattta tagcattttt cttagctcca aggtatatca attggattcc
    12841 attttcagaa ccactaatag tcgatggaaa aattgttttt gctgaaatgt tatttaatct
    12901 gatttccttt attccattag gtgtttgttt ccctttgata aaaactaatt tatctagttt
    12961 aagaatagtc gggacaggtt tcttgattag tttattgttt gagtgcttac agtatatttt
    13021 agcaataggt ataacagata taacggattt gactttaaat acgctaggtg tctgtgtagg
    13081 cttactgatt tatcaaattt ttataagagt gttcaaatca cagactagaa aatggatcaa
    13141 tatcttaggt atgcttatct tgttttactg ttactgcatt taattggtgt ttaactaatg
    13201 attaaaaagg agaatataat gactaaacgc gtcttaatca gcgtctcaga caaagcgggc
    13261 attgttgaat ttgcccaaga actcaaaaaa cttggttggg agattatctc aacaggtgga
    13321 actaaggttg cccttgataa tgctggggtg gataccattg ctatcgatga tgtgactggt
    13381 ttcccagaaa tgatggacgg tcgtgtgaag accctccacc caaatatcca cggagggctt
    13441 ctcgctcgtc gtgacttgga tagccacttg gaagcggcta aggacaacaa gattgagctc
    13501 attgaccttg tggtggtcaa cctttaccca tttaaggaaa ctatccttaa accagatgtg
    13561 acttatgctg atgcagttga aaatatcgat attggtgggc catctatgct tcgttcagca
    13621 gcgaaaaatc atgccagtgt tacagttgtg gtagatcctg ctgactacgc tgtggttttg
    13681 gacgaattgg cagcaaacgg cgaaacctct tatgaaactc gccaacgttt agcagccaaa
    13741 gtatttcgtc acacagcggc ttatgacgcc ttgattgcag aatacttcac agctcaagtg
    13801 ggtgaaagca agcctgaaaa actcactttg acttatgacc tcaagcaacc aatgcgttac
    13861 ggtgagaatc ctcaacaaga cgcggacttt taccagaaag ctttgcctac agactactcc
    13921 attgcttcag ccaaacagct caacgggaaa gaattgtcat ttaataatat ccgtgatgca
    13981 gatgctgcta tccgtatcat ccgtgacttc aaagatagtc caaccgttgt ggctctcaaa
    14041 cacatgaatc catgtggaat tggtcaagct gatgacatcg agactgcttg ggactacgct
    14101 tatgagtctg acccagtgtc tatctttggt gggattgtcg tcctcaaccg tgaggtggat
    14161 gctgcgacag ctgagaagat gcacggcgtt ttcctcgaaa tcatcattgc accaagctat
    14221 acggatgaag cgctagccat tttgatcaat aaaaagaaaa acttgcgtat ccttgccttg
    14281 ccatttaatg ctcaagaggc tagcgaagtg gaagcagaat acacaggtgt agtcggtgga
    14341 cttctcgtgc aaaatcaaga cgtggtcaag gcaagcccag ctgactggca agtggtgacc
    14401 aaacgtcagc caaccgagac agaagcgact gctcttgagt tcgcttggaa ggctatcaag
    14461 tacgtcaaat caaatggcat tatcgtgacc aacgaccaca tgacacttgg tgttggtcca
    14521 ggtcaaacca accgtgtggc ttctgttcgc cttgccattg accaagccaa agatcgtctg
    14581 gacggggcgg tccttgcttc agatgccttc ttcccatttg cggataacgt ggaagaaatc
    14641 gccaaagcag gaattaaggc catcatccag cccggtggct ctgtccgtga ccaagaatcc
    14701 atcgaagcag cggataaata cggcttgact atggtcttta caggtgtgag acattttaga
    14761 cattaagaag ataaaaggga agaaaacagt ttctttcctt ttttggctta aaatgctaac
    14821 tgaaacaaga ttaaaacgaa cttttttgat ataatgttgg taaataattc gcaaaagagg
    14881 ttgaggaatg aaactgcttg ttgtcggttc tggtggtcgt gagcatgcga ttgctaaaaa
    14941 gttacttgaa tcaaaagacg tgaaaaaagt ctttgtagtt cctgggaatg atgggatgac
    15001 tctggatggt ttggaattgg taaatatctc tatttccgaa cattctaaat tgattgactt
    15061 cgcaaagacc aatgatgttg cttggacctt tatcggtcca gatgatgccc ttgctgctgg
    15121 tatcgtggat gattttaacc aagctggact taaggccttt ggtccgacta gggctgcagc
    15181 ggagctggag tggtccaagg attttgccaa ggaaatcatg gtcaaatacg gcattccgac
    15241 agcaacctat ggcacatttt cagatttcga ggaagcaaag gcctatatcg aaaagcatgg
    15301 tgcgcctatc gtagtcaagg cggatggctt ggcgcttggg aagggtgtcg tcgttgctga
    15361 gacggttgag caagcggtcg aagccgctca tgatatgctt ttggacaata aatttggtga
    15421 ctcaggtgcg cgcgtggtta ttgaggaatt ccttgaagga gaggaatttt cactctttgc
    15481 ctttgttaat ggtgataagt tctacatcat gccaacggct caggaccaca aacgtgccta
    15541 cgatggcgat aaagggccta acacgggtgg tatgggtgcc tatgcgccag ttccacactt
    15601 accacagagt gtagttgata cagcggttga caccattgtc aagccagttc tagaagggat
    15661 gattaaagaa ggtcgccctt atctgggagt tctttacgca gggcttatct tgacagcaga
    15721 cgggccgaag gtcatcgagt tcaactctcg atttggagat cctgaaactc agattatctt
    15781 gcctcgctta acctctgact ttgcgcaaaa tatcacggat attctggatg gcaaggagcc
    15841 aaacatcact tggacggaca agggtgtgac tctgggtgtg gttgttgcat ccaagggtta
    15901 cccgctagac tatgaaaggg gcgttgagtt gccagccaag acagaaggcg atgtcatcac
    15961 ctactatgca ggggctaagt ttgcggaaaa tagcagagca ctgctctcaa acggcggacg
    16021 agtttatatg ctggttacca cagtagccac cgtcaaagaa gcccaagcca gcatctacca
    16081 agaactatcc caacaaaaaa tagaaggact cttctaccga acagatatcg gaagcaaggc
    16141 aattaagtaa agatataaga ataacgcgac gcagtcgcca aatacgataa tggtcgtcgt
    16201 ggtgaaaaga ccagaacagt gaatgttctg gtcaagggga aactttgaga ccttaggctc
    16261 aaagtttagg aatgaaaccg aaggtttgct tccgcctcca tcacctaaga ccattatcaa
    16321 aaagaaaaat aaaaattcac aaaatacgtt aatggtcgta tggtttgcga gcgttagcga
    16381 gctaatatag aataatcacc gccgttgtga aagaacgatt ggatgacaat ccaatcgttc
    16441 agggaaattg gaagaccttg ggtttccaat ttaggcatga gacacctttg gtggctgctg
    16501 ccgtccctca caagctaagg tgattgttga aaaagaggaa aaaggagaag aaatgaaacc
    16561 agtaatttcc atcatcatgg gctcaaaatc cgactgggca accatgcaaa aaacagcaga
    16621 agtcctagac cgcttcggtg tagcctacga aaagaaagtt gtttccgcac accgtacacc
    16681 agacctcatg ttcaaacatg cagaagaagc ccgtagtcgt ggcatcaaga tcatcatcgc
    16741 aggtgctggt ggcgcagcgc atttgccagg catggtagct gccaaaacaa cccttccagt
    16801 cattggtgtg ccagtcaagt ctcgtgctct tagtggagtg gattcactct attctatcgt
    16861 tcagatgccg ggtggggtgc ctgttgcgac catggctatc ggtgaagctg gagcgactaa
    16921 cgcagctctc tttgccctcc gtctcctctc tgtagaagat aagtccattg cggatgcact
    16981 tgccaacttt gctgaagaac aaggaaaaat cgcagaggag tcgtcaaatg agctcatcta
    17041 aaacaatcgg aattatcggt ggcggtcaac tgggtcagat gatggccatt tctgctatct
    17101 acatgggcca caaggttatc gcgctggatc ctgcggcgga ttgcccggcc tctcgcgtgg
    17161 cggaaatcat tgtggcacct tataacgatg tggacgccct ccgtcagttg gcagaccgtt
    17221 gcgatgtcct cacttacgag tttgaaaatg tcgacgctga cggtttggat accgttatca
    17281 aggatggaca actccctcaa ggaacagatc tgctccgcat ttcgcaaaat cgtatttttg
    17341 aaaaggactt tttgtcaaac aaggctcaag tcactgtggc accctacaag gtcgtgactt
    17401 ctagcctaga cttggcagat atcgacttgt cgaaaaacta tgtcctcaag actgcgactg
    17461 gtggctacga tggtcatgga caaaaggtta ttcgttcaga agcagacttg gaagcagcct
    17521 atgcgctagc agactcagca gactgcgtct tggaagaatt tgtcaacttt gaccttgaga
    17581 tttctgtcat cgtgtcagga aatggcaagg aggtgacgtt tttcccagtt caggaaaata
    17641 tccaccgcaa caatatcctg tctaagacca tcgtaccagc ccgcatttct gaaagtctag
    17701 cagacaaggc taaagctatg gcagtgcgaa tcgcagaaca actcaacttg tctggaactc
    17761 tctgtgtgga aatgtttgcg actgatgatg acgttattgt caatgaaatc gccccacgac
    17821 cacataactc tgggcactat tctattgaag cctgtgattt ctctcagttt gacacccata
    17881 ttctgggtgt tctcggagca ccattaccag tcatcaaact ccatgcgcca gccgttatgc
    17941 ttaatgtcct cggtcagcat gtcgaggctg ctgagcaata tgtgacagaa aattcaagcg
    18001 cccacctcca catgtatggt aaaatagaag cgaagcacaa ccgcaagatg ggacatgtga
    18061 ccttgtttag tgatgtaccg gatagtgtgg atgagcttgg ggaagggatt gatttttagg
    18121 acaagtctat gatacaaatt atcgttaata catttattga aaaggataag actggagcag
    18181 ttgttgaagt gttgtatgcc agtgctgacc aagataaggt acaagctaaa tatgaagaac
    18241 tagctgcaca ataccccgaa aattatttag ctatctatga tgtaccgctg gatacggatt
    18301 tgaatacact agatcattac ccgtctgtgt ttattgaaaa agaggagttt gagtagaaat
    18361 cttggtttac ctagatagct tattcccaac agcttaagaa gaaaggaaaa attaacacat
    18421 gatcaaccgt tactctcgcc ctgagatggc gaatatttgg agtgaagaaa ataaataccg
    18481 tgcttggctt gaggtggaaa tcctctctga cgaggcatgg gctgagttgg gggaaatccc
    18541 taaggaagat gtggctttga ttcgcaagaa ggcggacttt gacatcgacc gtattttgga
    18601 aattgagcag gagacgcgcc acgatgtggt ggctttcacg cgtgcggttt ctgagactct
    18661 tggtgaagag cgcaagtggg ttcactatgg gttaacttct accgacgtgg tggatactgc
    18721 ttatggttac ctctacaagc aggccaacga catcatccgt cgtgaccttg aaaacttcac
    18781 taatatcatc gctgacaagg ccaaggagca caagttcacc atcatgatgg ggcgtactca
    18841 tggtgtgcac gctgagccga caacctttgg tcttaaattg gcaacttggt acagcgaaat
    18901 gaaacgcaat atcgagcgtt tcgagcatgc agctgctggt gtagaagctg gtaagatttc
    18961 tggtgcggtt gggaactttg ccaatatccc accatttgta gaggagtatg tctgcgataa
    19021 acttggcatc cgtgcccaag aaatctctac acaagtcctt cctcgtgacc ttcacgctga
    19081 gtactttgcg gttcttgcca gcattgcgac ttcaatcgaa cgtatggcga ctgagattcg
    19141 tggtctacaa aaatctgagc aacgcgaagt agaagagttc tttgctaaag ggcaaaaagg
    19201 gtcttcagca atgcctcaca aacgcaaccc aatcggttct gaaaatatga ctggtctggc
    19261 gcgtgtcatt cgtggtcaca tgattacggc ttatgaaaac gtcgctctct ggcacgaacg
    19321 cgatatttct cactcatcag ctgagcgtat catcacacca gatacgacca ttttgattga
    19381 ctacatgctc aaccgttttg gaaatatcgt caagaacttg acagtcttcc cagaaaatat
    19441 gatccgaaac atgaactcga cttttggtct tatctttagc caacgggcta tgttgacatt
    19501 gattgaaaaa ggcatgaccc gtgagcaagc ctatgacttg gtgcaaccaa aaacagccta
    19561 ctcttgggac aaccaagtag actttaaacc acttcttgag gcagattcag aagtaacatc
    19621 acgtctcact caagaagaaa tcgatgaaat cttcaaccca gtttattaca ccaaacgagt
    19681 ggatgatatc tttgaacgtc ttggactagg tgattaatta aaaaataaac agcgagcttc
    19741 aatctcgctg tttatttttt atcgaaaaga cttagtcttc ttttctttta gtgagtccat
    19801 aggctgctag tgtggccatg agtcctgcga ctactagtcc tgcagaatcg tgagttcctg
    19861 tttcaggaag ttttttctct attaccacag gagctggatc ttgaggaaga gctttgcttt
    19921 cctcagcagg agcagttgat ggagctggtt ggcttgggat ttctagtttt ggtttttctt
    19981 cagcaatagc ggcttgtccg ttttcatcgc ctacatgtgt taccatagtt ccgacttcga
    20041 ctatttgagt aacggcttcc tgtgctacga cactatttac aagtgttttc acttccttac
    20101 catcggcaga agtgctcaca gagtagaagt tgctacgatg tccattgacg cccttagtaa
    20161 tgacttgtgt ttttcctttg agtaagagtg gattttcacg agtcactgtg gtaaatggaa
    20221 tttcttcttt ttggatatcc agtctaggtt ttacctcagt agttggtgca agaccacttt
    20281 catcaccctt gtgagttaca ggagcgccaa cttcaaccac ttggtttata acttctttgg
    20341 ttacctggct atcaaggact gtttctgttg tttttccatt ttcagtgagt acagagatgt
    20401 aatgagttcg ctcacctttg actcctgctg tgataatatt ttcctgacca gctgggaggt
    20461 taggattttc tttcttgata acttcaaatg gaatttcttc agttcttgtg atgagttctg
    20521 gtctggtttc aacattggca gccacttcat tttcatccag gcttcctgaa tgagttgcag
    20581 ctggtttgag gccttgaaga gcggctttta ggttggctac aagtgtgtca agctcagctt
    20641 gtttattacg gttgaggttg taatttagag ctgttttagc tgcgtcaagg gcctcaagac
    20701 tttctttact atatccttct aagtttgtag gaattttagc taattcttcg cggagagcat
    20761 tataattagc acggaagtgg tctttgttgt ggtctgcaaa ggcagtcatg agttcaaaga
    20821 tttcctcttc cttgtattca gcgcttggtc tatctgccca gattgaaagc atacttccga
    20881 ctgttggaag atctacttca ggatatttgg tagaagctag ttgattgaat ggtgtttttc
    20941 cagtattctc aatagctttc ttgaggaaac caccaccatc ttctggtttt tgaccaagaa
    21001 tgtagtacca gtcaccgttg gtattcaaga atttatagcc tttgcttgct aggtattgag
    21061 gtgatgcgag gttatatccc caccagcctt tagaccagta agaaatcaag acatctttgt
    21121 caaactgaac atcgtccttg tcttcatagt agaagccatc gttgaaggcc attggttgaa
    21181 gctctctttc tttggccata gctgcgaggg tgttggcata ttcggcaaat ttgccataga
    21241 gttgatacca cttgaggtag taccagcctt gggcactagt cgcatcgttg gcgtattcgt
    21301 cagtaccaaa gttgaaaatc tttgttttac ctgcaaagaa gtccatgtat ttaccgatga
    21361 gggcttttac aaagttcatc gcttcttcgt ttttcaagtc catagttgtt tttgaaactt
    21421 tatcaaagtg ggcttgagga tttttaatac ctaatttttc catggcaacc agcatagcat
    21481 ccatgtgacc tggactgtta atagctggga tgagaccgat gtccttagat ttagcgtatt
    21541 caattagctc tgtcacttct gcctgtgtta gtgcagtacc gtttggatcg tcgtagtaag
    21601 ctttagttcc ttcgataata gcttttttaa cgtcatcact agcataggtt tttccgttgg
    21661 cagtaatggt catatcattg agtagaaagc gaagtccgtc atttcctaga aggagatgga
    21721 catcagaata tccgagctca ctggccttgt ctacgatgcg tttgagctgg ttcagagtaa
    21781 agtatttgcg tccagcatcg attgagatta ccttgttttt ggcaagtttt tcaacctcac
    21841 gtttagcttc ttcttctttt tgagcttcag gcgtgagggt caagttgttg acagtttctt
    21901 gaagtttagc aatggcttga tcaatcgtat cttgttgggc acggctaagg ttgctatcga
    21961 gagagcgaat agctttttca gcttctttta cggccgtgac gctttctgca gtataacggt
    22021 tcaggtcttt tggtacctcg ttaagtgctt gctctgcaga ttcataatca gctgcgaagt
    22081 attcagcgtt ggcatttgca aaatgacgca tgagtttgaa gaggcgtgat ggtgaataac
    22141 gtgcagatgg agtgtcagcc caagcagcta ccataccacc gatgattggg atatcagctc
    22201 cttctgtttt tggtacagaa gtgattggtg tgtttttaat accattgagc ccctgatcga
    22261 gattgtacca gccttggcca tcagcgtttc gtccaagaac gtagtaccaa gcatcattgg
    22321 tattaaggat ttggtgacct ttttcagcta gtagtttaga agaagcgaca tcgtagtctc
    22381 cccaaccacc agtccacata gaaacgatga tgtctttgtc aaaactacca aagcttgtgt
    22441 cgctattgta gtagataccg tcgttaaagg ccattggttt gagaccgtgc gattttacaa
    22501 tacgagcgag gtcattggcg taggcaataa atttttcata gccttttaca gggtagcctt
    22561 cgtttggata gtatttatca gcttgaagca cactccaacc tttagcatct gtcgcatcat
    22621 tggcatattc atcaagtccg atgttgaaga tttcagtctt tttcgcgaaa taagcagcat
    22681 acttgtcgat aagggctttt gtaaaagcga cagcttgttc gttgtcaaga ttgacagtac
    22741 gggctgattc cttcccaaaa tagctaaagt tagggttttg gattcccaat tctttcatgg
    22801 cattgagaat cgcatccatg tgcccaggac tatttactgt cggaatgaga ccgatacctt
    22861 tatctttggc atagttaatc agatctgtca tttgactttc tgttaagtga ttgccgtttg
    22921 gatcgtcgta ataatcattt gtaccttttt caatggcgcg tttgacatcg tcactggcat
    22981 aggtcttgcc gttagctgtg atgctcatat cgtccaacat gaaacggagt ccatcatttc
    23041 cgactaatag gtgtaaatca gtgtagccat aatgtttcgc tttatcgatg atttccttga
    23101 gctgttctgg tgagaaatat ttacgtccag catcaataga aacaattttc tttttcgcta
    23161 gtttttcatt tacagttgca gcacgttcct ttcctgcctc tgtttccggt ttgtcagcct
    23221 ctgctttcgc ttcatctttt ttagctggtt tatccttgtc agtcttgtct gtatttgact
    23281 ctttagaatc aacctctttc gcttcttcct ttttagggct agcttcttct gcctttttat
    23341 tagcagtttc tttttcagca gaagttggag ttaccacttc tgctttatca ctaggagttg
    23401 aactaacttc ctcttgtggt ttttcttctg tttttggaag actagctacc ttatcagtag
    23461 ctggagtttc tgtttctaca gtttttggag cttctggttg aagctctgct ttaggtgttt
    23521 cctcagtccg attttcggat gattgagggg aatcagaaac cgtatggatg gtcggttggt
    23581 tttctgtagt agtaggagta actccatcgg ctgcaacagt ctgtgcttgg aaggcaaatc
    23641 caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc tgttgttttt
    23701 catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt atataaatca
    23761 acgcctttat tttatttctt atattaacga gagtcaagag gagatgacaa aaaactataa
    23821 taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgaa aaatacatat
    23881 atatatctag tataattttt ggttctattt ctataaaata ttccacaaat tatagaatct
    23941 tccaaaaata ggtaagcgct acctttttgg tgtggtataa taagcataga aaaagcccga
    24001 gcgattaggc tcaggctttc ttcttagtga tcacggtcac atgagatgaa tttaatcttg
    24061 tagtaatcag atcgtttgta agtttcactg tattctaaaa cttggccagt tgattcgagt
    24121 ttggtgattt tagtttgtag gacagtaggg aattgttcat cgactccgag gactgaagcc
    24181 gcatgttctg gagttggaaa gactatttcg ttgatttctt caaagtgttc atcattcatg
    24241 tgaatgtggt agtctaactt gaaacgatta tagatagaac tatagtattc aaggtttgga
    24301 taatttgcgt tgatatattg ttctgggatg taggatgtat ggtagatata aacgacaccg
    24361 tttgattcgc ggatacgttc aatcttgtag tagaattgat cgccgcgtag acccaatttt
    24421 tccaagtaaa caagcttgtt tccgcgttca attgaaagaa cagttacctt atcatcttta
    24481 gcattgaaga gttcaatatc tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg
    24541 aaggttcctt ttccttgttg gcggacaata tagccatctt tggcaaggtc gtttaaggcg
    24601 cgaacaactg tgatagagct gacatcgtac attgaaatga gttctgcttc agtgtaaaat
    24661 ttatctccac tgctaaactg cccagagatg attttatttt ttaattcgtc ttttatgtat
    24721 tgatatttgg gaattgccat atttttacct ctattttcct tctccataga aaattttacc
    24781 ataaaagcga aaaaaatagt agtcttttga ataaaaaatt agaataatag tttgaaaaat
    24841 taagcgatat agggattgct catattttat caatgtattc tatacaaaat tattttaggt
    24901 cctatattcc gaatttaaag agcgtttgaa atgggtctaa aaatgtttga aactaattga
    24961 atgtgtgtat aatagtaaaa atgcagtaaa tatcccgaca atttctattg acaattcaaa
    25021 cagattggtt tataattaat ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg
    25081 tagttttatg acacgatttg agatacgaga tgatttctat ctcgatggaa aatcatttaa
    25141 gattttatct ggtgccattc attattttag ggttcctcca gaggattggt atcattcgct
    25201 ctataacttg aaggctcttg gttttaatac ggtagagact tatattgctt ggaatttaca
    25261 cgagcctcgt gaaggtgagt ttcattttga cggtgatctg gatttagaga aatttctcca
    25321 aatagcgcag gatttgggtc tctacgcaat tgtgcgtccg tctccattta tctgtgcgga
    25381 atgggaattc ggtggcttac cagcttggct cttgaccaag aacatgcgaa ttcgctcatc
    25441 cgacccagca tatatcgagg cagttggtcg ctactatgat cagttattgc caagactggt
    25501 gcctcgtttg ttggacaatg gtggcaatat tctcatgatg caggttgaaa atgagtatgg
    25561 ttcttacgga gaagataagg cttacctgag agcgattcga cagctaatgg aagagcgtgg
    25621 cgtaacctgt cctctcttta catcagatgg tccatggcga gctactctga aagctggaac
    25681 cttaattgaa gaggacctct ttgtaacagg aaactttggt tctaaggcac cttacaactt
    25741 ttcgcagatg caggaattct ttgatgaaca tggtaagaaa tggccactca tgtgtatgga
    25801 gttctgggat ggttggttta atcgctggaa agaaccgatt atcacacggg atcctaagga
    25861 attggcagat gcagttcgag aggttttgga acaaggctct atcaatcttt acatgttcca
    25921 cggtggtaca aactttggtt tcatgaatgg ttgctcggct cgaggaactt tggacctgcc
    25981 acaagttacg tcttatgatt acgatgccct tctggatgaa gaaggaaatc caactgctaa
    26041 atatcttgca gtcaagaaga tgatggcaac acatttttca gagtatccgc agttggaacc
    26101 actctacaaa gagagtatgg agttggatgc tattccacta gttgaaaaag tttctttgtt
    26161 tgaaacctta gatagcttgt caagtcctgt agaaagtctc tatcctcaaa agatggagga
    26221 gctgggacaa agttatggct acctacttta tcgaacagaa acaaactggg atgcagaaga
    26281 agaaagactt cgtatcattg atggtcgaga tagggcccag ctgtatgtcg atggtcagtg
    26341 ggttaaaact caatatcaga cagagattgg ggaagatatt ttttatcaag gtaaaaagaa
    26401 agggctatct aggttagata tcttgataga aaatatgggg cgtgtcaact atgggcataa
    26461 gttcttagcg gatacgcaac gtaagggaat tcggacaggg gtctgtaagg atctgcattt
    26521 cttactaaac tggaaacact atccacttcc actagacaat cctgagaaaa ttgatttttc
    26581 aaaaggatgg actcaaggac aaccagcctt ttacgcttat gactttacag tcgaagagcc
    26641 aaaagatact tacctagact tgtctgagtt tggtaaggga gttgcctttg tcaatgggca
    26701 gaatctagga cgtttttgga acgttggccc aactctctca ctttatatcc ctcatagcta
    26761 tctcaaggaa ggtgccaacc gcatcattat ctttgaaaca gaaggtcaat ataaagaaga
    26821 gattcattta actcgtaaac ctacactaaa acatataaag ggggaaaact tatgacaatt
    26881 gtaggatgcc gtattgatgg acgtttgatc cacggacaag tagccaatct ttgggctgga
    26941 aaactaaatg tttcacgcat tatggttgta gacgacgaag ttgtcaacaa cgatattgaa
    27001 aagagtggtt tgaaacttgc gacaccacca ggtgtgaaat tgagtatttt gccagttgag
    27061 aaagctgcag ccaatattct tgctggtaaa tacgatagcc aacgtctctt tatcgtggct
    27121 cgtaaaccag accgcttcct tggcttggta gaagcaggtg taccacttga aacccttaat
    27181 gttgggaata tgtctcaaac accagaaact cgttctatta cacgttctat caacgtagta
    27241 gacaaggatg tggaagactt ccacaaactg gcagaaaaag gtgttaaact tactgctcag
    27301 atggttccaa atgatccaat ttcagacttt ttgagcttat taaaatagga aaaaaatttt
    27361 taggaggtca ttgttatgat acaatggtgg caaattttac ttctcacttt gtactcagct
    27421 tatcaaatct gtgatgagtt gacgatcgtt tcatctgcag gttcccctgt atttgctggt
    27481 ttcattactg gtttaatcat gggagatgtg actactggtt tacttatcgg tggtaacttg
    27541 caactgttcg ttcttggggt tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct
    27601 ggtgcggttc ttgcgacagc cttctctgtt tcacaaggaa ttgatgcacc gcttgcaatt
    27661 actacaatcg ctgtaccagt agcagctctc ttgacttact tcgacgttct tggtcgtatg
    27721 actactacct tcttcgctca ccgtgtggat gccgcaatcg aacgctttga ctataaaggt
    27781 attgaacgca actacttgct tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc
    27841 ttctttgccc ttgcttttgg tggtgccttt gtacaatcag tagtagactt cgttgaagcc
    27901 tacaaatggg ttgcagatgg cttgacactc gcaggacgta tgcttccagg tcttggattt
    27961 gcaatcttgc ttcgttacct tccagttaaa cgtaaccttc actaccttgc tatgggattt
    28021 ggtttgacag ctatgttgac tgttctttac tcatatgtaa caggtcttgg tggcgctgtt
    28081 gctggtatcg taggtactct tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac
    28141 ttcaaaggtt tgtctatgat tggtatttct atcgtaggta ttttccttgc agtgcttcac
    28201 ttcaaaaata gccaaaaagt agctgtagca gcaccttcta caccatcaga aagtggggaa
    28261 atcgaagatg acgaattcta attacaaact tacaaaagaa gattttaatc aaatcaacaa
    28321 acgtagcttg tttactttcc aattaggttg gaactacgaa cgtatgcaag cttctggtta
    28381 cctttacatg atcttgcctc agttgcgtaa aatgtatggt gatggaactc ctgaattgaa
    28441 agaaatgatg aaagttcata ctcaattctt caatacttca ccattcttcc ataccattat
    28501 cgctggtttt gaccttgcca tggaagaaaa agatggtgta ggttcaaaag acgctgttaa
    28561 cggtatcaag acaggtttga tgggaccatt cgctcctctt ggggatacaa tctttggttc
    28621 acttgtacct gctatcatgg ggtcagtcgc agcaactatg gctatcgctg gccaaccttg
    28681 ggggatcttc ctttggattg cagttgcagt agcgtatgac atcttccgtt ggaaacagtt
    28741 ggaatttgct tacaaagaag gggttaacct tatcaacaac atgcaaagta ccttgacagc
    28801 tttgattgac gctgcatctg tacttggtgt cttcatgatg ggtgctcttg tagcaacagt
    28861 gattaacttt gaaatttctt acaagttgcc aatcggtgaa aagatgattg atttccaaga
    28921 catcttgaac caaatcttcc cacgtttgct tccagcaatc tttactgcct ttatcttctg
    28981 gttgcttggt aaaaaaggta tgaactctac taaagctatc ggtattatta tcgtacttgc
    29041 tttggctctt tctgcccttg gtcactttgc acttggaatg taattcctta tgactaaatc
    29101 attaattttg gtgagccatg gtcgcttctg tgaggagctt agaggtagca cagaaatgat
    29161 tatgggccca caagacaaca tttacacagt agctcttctt ccagaagatg gcccagaaga
    29221 atttactgct aaatttgaag ctgttattga aggattggat gatttcctag tctttgcgga
    29281 tcttctcggt gggacacctt gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat
    29341 tgacctttac gcagggatga atcttccaat ggtgattgaa tttatcaatg cgagccttac
    29401 aggcgcagat gcggactaca agagccgtgc tgcagaaagc attgtgaaag ttaatgacct
    29461 gttagcgggc ttcgatgatg acgaagatga ataatactct tcgaaaatct cttcaaacta
    29521 cgtcaacgtc gccttgccgt aggtatatgt tactgacttc gtcagtctta tccggcaacc
    29581 tcaaagcggt gctttgagca gcctgcggct agtttcctac agattttagt tggaactcga
    29641 ttcaattcat gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa
    29701 tggagcttac tcccattccc atatttaata gaaaaagagg aactcaatgc tacattatac
    29761 aaaagaagac ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacagcc
    29821 tgatgtatgg agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt
    29881 cctacaagaa atcgctgata aacatgacta tattaaggtt atcttgacag gtgctgggac
    29941 ttctgcttat gtgggagaca ccttgctacc ttactttaag gaagtctatg acgaacgcaa
    30001 atggaatttc aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa
    30061 aaaagatgtg gcaactgtcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt
    30121 ggcgactgtt gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg
    30181 tgcagcagat ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt
    30241 gcaaccagct gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat
    30301 gttgacaact ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga
    30361 agttgtatct agtcttgccc gtaaagtttt agacaaggca gaagatgtca aagagctcgt
    30421 tgatttagac tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca
    30481 tgaagctcag ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag
    30541 cccagttggc ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt
    30601 ctttggtaca acgacagact atactcgtaa gtacgacttg gacttggttc gtgaagttgc
    30661 tggtgaccag attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa
    30721 tgtcaaagaa gtgtcccttg gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc
    30781 ttacatcgtt tatgcccaac tctttgccct attgacttca ctcaaggtag aaaataaacc
    30841 agatacaccg tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga
    30901 atatcaaaag taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat
    30961 aaaccataga ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg
    31021 agaacagaat gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct
    31081 tggcctatcg atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga
    31141 ccatcttgcg ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat
    31201 ttgatgactt tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg
    31261 tagcgggtcg tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg
    31321 ttaataatgc tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg
    31381 aagttgaaga agtaagcgat catggcttga ctctctacac agaacgtaca gatgggacag
    31441 gagggttccc tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct
    31501 atgaaattag ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca
    31561 gctatttcaa cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa
    31621 acacagaggg catttactca atcactcctg acggtgttcc tgccaaaact ccagaagcca
    31681 accgtgatgt ggtcaaacac atctacaatg gtaccttgtt gaaggatatc tttgcagaag
    31741 aagatgagca aatccagctg gcatcaggtt tggatcaccc atttgccctt cctgtaggcc
    31801 atgacaatgc tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag
    31861 aagctccttg ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc atcataggag
    31921 gtcagccaat gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca
    31981 ttcacagtga ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga
    32041 cacgttatga acttgttgtg aaataaaaaa agctggtcaa aaagtcttta aaattaaaat
    32101 aatgcatatt gtcaggtgat ggaaagtttg ataatatgcg ttttattata aaatgattta
    32161 ctttatctta tcctgaaatg gtgttatttt tgagttatct ggcttgactt tcttgatgaa
    32221 aattatataa tagttgtaac aataataatt acaacgagaa aagaggacca tttatgacct
    32281 atgaatacaa gagtcacatt tatttggcag agacagcttt aaatgtaaag gatttggcca
    32341 gtcaaacagc cttttatcag caagttattg gtttagaaat cttatctcaa actgagacag
    32401 agtccattct aggccttggt ggaaaagtct tggtacagct gattcaagca caagagagcg
    32461 gagaagtgag ggaacattat ggtctttacc atttggccat tctcttgccc acacgcaagg
    32521 ctttggctga tgtcttgaaa cacctgacag atttacagat tcctcttgtc ggcggtgcag
    32581 accatggtta cagtgaagct atttacttgg aagatttgga gggaaatggc attgaactct
    32641 atcgagataa gccagtttcc acatgggata ttcgagaaga tggacgcatt atcggagtga
    32701 cagaggctct tgcggcgcag gacatttatg agttggggga aagagtagag ccctttatcc
    32761 tggcagaagg tacgagaatg gggcatattc atctttccgt caaggatagt cgaaagtcca
    32821 gccagtttta tcaaaaggtg ttagggctag aggataaatt cagtgtgcct agcgctagtt
    32881 ggattgcggc tggagattac catcatcatt tagcagttaa cgaatgggga ggaaaaggtc
    32941 tggcttcgcg taagcaaggc ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata
    33001 aaaaagaact attaacgatt gcccaacgag cacaagaagt tgacgcacca atcaaatgga
    33061 tgacatcgag ccaattggaa atcacagact cagatggcat cgtgacccgt attcgtttag
    33121 caaggtaaaa ttaggaattt ttaataagtt ataagtattg ctagtttgct ttttgaacgg
    33181 tctttggtaa cagaactgcg tgagctggat gggcgagaat tttgacaaag aagctgatta
    33241 gagatataat gaagaaaaat cgagcaagga aaaagaaatg acaaattcaa agtatattac
    33301 ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg aaggagatcg
    33361 tgactgtgct gatattgtga cgcaactgac agcagtgaga tctagtgtag agcgcgtgat
    33421 tgagatgata attaccgaaa atcttactga atgtatcaat cagccactag atgattctga
    33481 agctcaaaag gaacgcctag aaaaggctat ccgatacttg attaaacgga aataaatgaa
    33541 tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa tgtgagtcaa
    33601 aagaagttgt aaaaaatctt taaaattaaa aaaacgcata gtatcaggtg ttgaatgtac
    33661 tgaccccaaa aagttagatt ttttctgtct aacttttggg gtgcagttca taagaacctt
    33721 ggtaatatgc gttttattat gtagagactt atactcttcg aaaatctctt caaaccacgt
    33781 cagtttcacc ttgccgtaga tatggtt
//
LOCUS       DBEJJE010000021        33248 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEJJE010000021 DBEJJE010000000
VERSION     DBEJJE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33248
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.21"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(154..1134)
                     /locus_tag="ACL3F5_000993"
     CDS             complement(154..1134)
                     /locus_tag="ACL3F5_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0514818.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1649..3664)
                     /gene="recG"
                     /locus_tag="ACL3F5_000994"
     CDS             complement(1649..3664)
                     /gene="recG"
                     /locus_tag="ACL3F5_000994"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0514819.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3683..4786)
                     /gene="alr"
                     /locus_tag="ACL3F5_000995"
     CDS             complement(3683..4786)
                     /gene="alr"
                     /locus_tag="ACL3F5_000995"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0514820.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4776..5138)
                     /gene="acpS"
                     /locus_tag="ACL3F5_000996"
     CDS             complement(4776..5138)
                     /gene="acpS"
                     /locus_tag="ACL3F5_000996"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0514821.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5183..6214)
                     /locus_tag="ACL3F5_000997"
     CDS             complement(5183..6214)
                     /locus_tag="ACL3F5_000997"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0514822.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6216..7247)
                     /locus_tag="ACL3F5_000998"
     CDS             complement(6216..7247)
                     /locus_tag="ACL3F5_000998"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0514823.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPELFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7328..9841)
                     /gene="secA"
                     /locus_tag="ACL3F5_000999"
     CDS             complement(7328..9841)
                     /gene="secA"
                     /locus_tag="ACL3F5_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0514824.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9987..10274)
                     /locus_tag="ACL3F5_001000"
     CDS             complement(9987..10274)
                     /locus_tag="ACL3F5_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514825.1"
                     /translation="MLNLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10268..10843)
                     /locus_tag="ACL3F5_001001"
     CDS             complement(10268..10843)
                     /locus_tag="ACL3F5_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HGR0514826.1"
                     /translation="MKTIVKICLVALSAFLLLFAGKNVFADSNSHDNLNSLEVSDRSF
                     RNGELLKSYLVKDKDRIYFDYDKAVQDKQAKDVIDMGLLVETISEDYSSNTFTPAKYF
                     KAGLPVHGNYCGPGYNGEGFTLPVVDVLDQGCQNHDRCYKWGAGIGANCECNRQLVDF
                     IKVNRRWIPESALWVADAIRVYFETIGAIGC"
     gene            11305..12156
                     /locus_tag="ACL3F5_001002"
                     /note="rgg1518"
     CDS             11305..12156
                     /locus_tag="ACL3F5_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator
                     Rgg1518"
                     /protein_id="HGR0514827.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYIWNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVEILEKE
                     INDFSNL"
     gene            complement(12378..12728)
                     /locus_tag="ACL3F5_001003"
     CDS             complement(12378..12728)
                     /locus_tag="ACL3F5_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514828.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(12869..13204)
                     /locus_tag="ACL3F5_001004"
     CDS             complement(12869..13204)
                     /locus_tag="ACL3F5_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514829.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13295..14605)
                     /gene="der"
                     /locus_tag="ACL3F5_001005"
     CDS             complement(13295..14605)
                     /gene="der"
                     /locus_tag="ACL3F5_001005"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0514830.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14619..15332)
                     /locus_tag="ACL3F5_001006"
     CDS             complement(14619..15332)
                     /locus_tag="ACL3F5_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0514831.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYKLVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15329..16225)
                     /gene="dnaI"
                     /locus_tag="ACL3F5_001007"
     CDS             complement(15329..16225)
                     /gene="dnaI"
                     /locus_tag="ACL3F5_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0514832.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16226..17395)
                     /locus_tag="ACL3F5_001008"
     CDS             complement(16226..17395)
                     /locus_tag="ACL3F5_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0514833.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKIQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17396..17869)
                     /gene="nrdR"
                     /locus_tag="ACL3F5_001009"
     CDS             complement(17396..17869)
                     /gene="nrdR"
                     /locus_tag="ACL3F5_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0514834.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18009..18374
                     /locus_tag="ACL3F5_001010"
     CDS             18009..18374
                     /locus_tag="ACL3F5_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0514835.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18379..19074
                     /locus_tag="ACL3F5_001011"
     CDS             18379..19074
                     /locus_tag="ACL3F5_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514836.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19091..19858
                     /locus_tag="ACL3F5_001012"
     CDS             19091..19858
                     /locus_tag="ACL3F5_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514837.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20211..21410)
                     /locus_tag="ACL3F5_001013"
     CDS             complement(20211..21410)
                     /locus_tag="ACL3F5_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514838.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKGLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21407..22300)
                     /locus_tag="ACL3F5_001014"
     CDS             complement(21407..22300)
                     /locus_tag="ACL3F5_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514839.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22423..22614
                     /locus_tag="ACL3F5_001015"
     CDS             22423..22614
                     /locus_tag="ACL3F5_001015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514840.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            22982..23195
                     /locus_tag="ACL3F5_001016"
                     /pseudo
     CDS             22982..23195
                     /locus_tag="ACL3F5_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23610..24227
                     /locus_tag="ACL3F5_001017"
     CDS             23610..24227
                     /locus_tag="ACL3F5_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0514841.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24547..25434)
                     /gene="scrK"
                     /locus_tag="ACL3F5_001018"
     CDS             complement(24547..25434)
                     /gene="scrK"
                     /locus_tag="ACL3F5_001018"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0514842.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25583..27466)
                     /locus_tag="ACL3F5_001019"
     CDS             complement(25583..27466)
                     /locus_tag="ACL3F5_001019"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0514843.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEVKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            27842..29296
                     /locus_tag="ACL3F5_001020"
     CDS             27842..29296
                     /locus_tag="ACL3F5_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0514844.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAIQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29277..30242
                     /locus_tag="ACL3F5_001021"
     CDS             29277..30242
                     /locus_tag="ACL3F5_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0514845.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30278..31552)
                     /locus_tag="ACL3F5_001022"
     CDS             complement(30278..31552)
                     /locus_tag="ACL3F5_001022"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0514846.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(31552..32724)
                     /locus_tag="ACL3F5_001023"
     CDS             complement(31552..32724)
                     /locus_tag="ACL3F5_001023"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0514847.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32855..33103)
                     /locus_tag="ACL3F5_001024"
     CDS             complement(32855..33103)
                     /locus_tag="ACL3F5_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514848.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9713 a         7469 c         6216 g         9850 t
ORIGIN      
        1 ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttgtttcat tttactatat
       61 ttccatgata aaacgcatag tatcaagttt ttttaatccc ctgatactat gcgtgtttgt
      121 aatttttaag attttgtgct tagagtcgac tccttatttt agatatttaa aaggaatctc
      181 acttccacag agccagttgt agacttggtc attgacaaat acattcatgg cttcgtgagc
      241 atactcaggc atgatacgat aggttttatc gcaggtcaga cgattataaa tcgcaaactg
      301 ggtaatggga tagcaaacat cgtcgtccaa gcccgtaatc atcttaacct caccttggat
      361 acgatgggca agatttttga catcgatata ggcaagggtc gccatgattt cctcctctgt
      421 ttcatggaag gggtcgtgaa acttgaaata acggaaaagt tcgtcgtaag cctcgctagt
      481 attaccaatt tcaatcaccc gtctgaagtc tgacaagaag ggataaatgg caactgtttt
      541 ctgaattcga ggattgagcg ctgctgcaac tagagctaga gcccctcctt gtgaggcacc
      601 ataactagaa agacgcttct catcaacctg agacagacta gcaacaattt cgaccaactg
      661 gtaaatatcc agataaacat ccttataaaa gaggtggtcc cgaccttcca tagcaccacg
      721 gataatatgc cccttcacgg tatttcctaa aggagaacgc aagccgtctt gtgagtaacc
      781 tgactggccc cgcacatcca tggaaacaac accgtaacca gctacggtga agcccagcat
      841 gtcggcccag tcccagccac gtcccatata accatgaaaa tggaagatta gtggaacctt
      901 ctcctcactc tttggaagaa caatgcgtgc atagaccttt ccttccttgc ttccttcaaa
      961 tgttaactca tagcacttga cttgaggaat gtggaaatct ctttcctcca agtggtagga
     1021 tggaggtgtg gaaacatttt tcacttcccc atcccagaaa gcatcaaagt cttccggaac
     1081 ctcatccctt cctctatagg tcttaatttc ttctagcaaa gctggatttt tcatagcatg
     1141 ctccttttat tttgtaatcg ttaccacaac tgtagcatat ctatgtaatc aatgcaagaa
     1201 agaagggtaa atagaaagtg aatttagatt ctttactttt aggatgatgg gctgaaagta
     1261 gttttagaaa cgaaaaaaga gcatttcgct ctctcttctg tttatactag ttttttgctt
     1321 ccttcttttg gaaagtggtt tggtaattta ctttaatcgt tactgtcata tgagagtcct
     1381 cgtttctttt tgatgactct agtataagag ccaaacctaa aaactagctt aatactcttc
     1441 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat atatatgtta ctgacttcgt
     1501 cagttctatc tgccacctca aaacggtgtt ttgagctgac ttcgtcagtt tcatccacaa
     1561 cctcaaaaca gtgttttgag caacctgcgg ttagcttcct agtttgctct ttgattttca
     1621 ttgagtataa gttttcctta gagaaagctt aatccagatg ttctttcttt tccagatgaa
     1681 gggcaatcat gcgccactct ggatcttctt gccaagcttc tatagaacta atgtagctag
     1741 caacctttct tgcttcttct aaaatcggaa aatcttcgat aatatcagcc acttggaact
     1801 ctggaagtcc tgactgtctg gttccaaaaa tctcaccaga accacgcatt ttcaaatctt
     1861 cctccgcaag gacaaatcca ttggtcgttt ctgtcatgat acgcatgcgg tctttcccag
     1921 aatccgtctt gggattagca acgagaacag cgtaggactg cttgtccccc cgaccgacac
     1981 gacctctaag ctggtgaagt tgactgagac cgaagcgatc ggcatccatg ataatcatga
     2041 cagtcgcatt gggaacgttg accccaacct caataaccgt cgtcgaaacc agaatatccg
     2101 tctttctctc cttgaaatcc tgcatgatct ggtctttttc gtcactcttc atcctaccat
     2161 gtagaagagc cacctctgcc ttgcctgcaa aatgagtcgt caactcctct gataaggcaa
     2221 tggcattttt caaatctaga gcttctgatt cttcaatcaa aggagagatg acatagactt
     2281 gggaaccttt ttgaatttcc ccctctaacc aagtcaagac ctgaggtagt tgctcatgtt
     2341 tgatccagcg cgtcacaata ggcttccgac ctgctggcat ctggtcgata atggaaacat
     2401 ccatatctcc aaaggctgtg atggcaagcg tccgtggaat gggagtcgcc gtcatcatga
     2461 ggacatctgg attgtcacct ttttcccgta aaatacgcct ttgccctaca ccaaaacggt
     2521 gctgctcatc gataataatc aaaccaagac gagcatactc caccccatct tgtatcagag
     2581 cgtgagttcc tataatcaaa tcagcctcac ccttggcaat ggtctccaag acttctctct
     2641 tttctgcagc tttcaaggaa cctgtcaaga gagccagttt caaattggga aaaaggttct
     2701 gtaaactctc aaagtgttgc tctgcgagga tttctgttgg taccattagg gcagcctgat
     2761 aacctgctgt cactgccgca aacatggcca agccagcgac taccgttttt ccactcccca
     2821 catccccttg taggagacga ttcatgtggt ggtcggactt catatcagtt aaaatttcct
     2881 gcaaactctt ttcctgagct tgggtcaggg caaaaggaag acttgcttta actgctgtca
     2941 ctttttcctg agaccaattc agaaccagac cacttccctg aactctattt tcagacttga
     3001 gcatctgcag ctgcatttgg aaataaaaga gttcctcaaa ctttatacgg cgaagagcct
     3061 gcttgtattc tgccaaatac tttggaaaat gcatagcacg gactgcctga caacgggaca
     3121 tgagtttgta tttgtctagt aaagactggg gcagattttc ttctatcaag aggtccagtc
     3181 cctgatcaaa agccgtcttg atgaccttga ccagactggc ctgactgatt ccctgagcca
     3241 gacgatagac aggctggagg tcatcttcta cctgagccag aaccttcatc ccagtcagac
     3301 tagccttagc gcggtcccat tttccaaaga cagcaagggt tgctcccaac tctattttat
     3361 cagccagata gggctggtta aagaaattca ccgcaaaaac gacctctccc tgcttgagac
     3421 taaaacgcag gcgattgcgc ttgaaaccat aatactggac actagcagga gtcactacct
     3481 gaccagaaag aactgccttc tcaccgtctt ccagctccag cacctgcttg gttttgaagt
     3541 cttcataacg gaaaggaaag tagagcaaga gatcttgcaa gttttcaatt cctagtttgg
     3601 cgtatttttc tgctgacttt ggtcccacac caggcaagac atgcaagggt tgatgtagat
     3661 tcatgctcca ctcctttctt ttctaataat attctctcgg aatacggtcg ctgaggaggc
     3721 aaaccacctc atagttaatg gttacgcggt aggtcgctac ctgagttgca gtgatttcct
     3781 tatccccatt ggagccaatc aaggttacct tggttcctag cggataaagc ttaggcaatc
     3841 gaatagtgat ttggtccatc gaaaccctgc cgacaattgg gcaagcttgg ccatctacca
     3901 agacagagaa attttgcatg tctcttgtcc atccatctgc atacccgatt ggcacggtcg
     3961 cgatgacttg ctcgctatcc gcttgataag ttgctccata gcccatgcaa gctccagctg
     4021 gaactgtctt gacatgaacc agagcagact ccaaggtcaa ggccggtatc aaatcataag
     4081 gcaaatccaa gaccgctcca cttggattga ggccatacat ggcatctccc atacgaaccg
     4141 cattgaaaat agtctctaca tgccaaagag tcgttgcaga attgctagca tgaaccagct
     4201 ctggaacttc cttcatacta gctaaaatag ttttaaaccg ttctaactgg gcattaaaat
     4261 agtcatctga ttcctcatca gcagtagcaa agtgggtaaa gattccttca acacaaacac
     4321 cgtgttgttg gagcaaatct tgagcctgct caacctcact tgcctctcta aaaccaatcc
     4381 gtcccatccc tgaatcaatc ttgaggtgga ctgtcaatcc agttaggtcc acttccttat
     4441 ctaagagtgc ttgaatccac tccagtccag ccactgtcaa ggtgaagtca tattctttag
     4501 ctagagcaac agcttcgatt tcagaaactc ctaaaatgag gattggcttg ctgagtccag
     4561 cttgtctgag ttcaatggct tcatcgatat tggaaacgca aaagccatca acatcatctt
     4621 gaattgcctt ggcaacggca acagctccat gaccataagc attggcctta accacagcca
     4681 acttgagcgt tccttgaggg atatgagccc ccatttgctg aatattttgt cgaatagctc
     4741 ccagatgaat cagagccttg gttggtctat gtggactagc tttcatgatt ttcctccaaa
     4801 atgacactgg ctgtcacaaa ctgatcggtg tggctgatag acagccaaat ctttcctgaa
     4861 aatggtgcct gactaaaata aggcgcccca cgttcattgt tcaagacttc caaatcctga
     4921 aaaccgagct tgctaatgcc cgttcccata gccttggaaa aggcctcctt agccgaccag
     4981 cgaccagcta aatattctat ttgcctgcgt cctttgagac tggtgaagcg ctccatttcc
     5041 tgagcggtca gtacacgctt agcaaatcct tcatgtcgtg taactgcgct ttctatcgaa
     5101 gccaattctt cgatgtcaat tccgtgtcca actatcattc tcatcaaaag gagttgagat
     5161 tccccaactc catccttttc acttattttg tcaaggtaac ataaatctct tctaccaagg
     5221 cctctgtatt ttcccaacct aggcaagggt cagtaataga gcaaccaaag atctctggtt
     5281 ggttttgacg accatctgct aggtaagatt caatcataaa tcctcgaacc gtctttttaa
     5341 ttttctcatt ccaatcacga ttctgcaagg tctggcgaac aattcgaatc tgctccatat
     5401 attgcttgcc tgagttatca tggttggtgt caatgaggat aaaaggattt tcaagtccca
     5461 tggtttcata gcgttcaatg gcttggagta gattttcata gtagtaattc ggcatataat
     5521 tgccatactc gttgactgct ccacggagga taacatgggc caaaggatta cctgatgtct
     5581 caacttcctg cccatgataa aggaaggttt gcttgttttg agcagcatag atggcgttaa
     5641 acataacacc caaatttcct gaggttggat ttttcatccc tactggtgca tcaatcccag
     5701 aagccacaaa gcggtgctct tggtcttcca cagaacgagc tccaacggca tggtagctga
     5761 ccaagtcatc caccaagatc agatttgacg gataaagcat ctcatctgcc gttgtcaaac
     5821 cagtctctgt aatcacgcgg tagtgcaact ggcgcacagc ctgcaagcca ttaatcaggc
     5881 ttggagcctt agaagtatct ggctggtgaa ctaatccttt atagccgtct ccattggtac
     5941 gaggcttagc agtatacacg cgcatgacca tgaaaatctt atccgctacc ttcttttgca
     6001 aggcagataa acggcgagca tattccaaga ccgcctcttc attatcagaa gagcaaggac
     6061 caatcaccaa gagaatacgg tcatcttccc ctgaaataat atctgccaat tccctgtcac
     6121 ggctttcctt gagtctcaag gcttccgcag acaattgggt ttcagccttg atgacttcca
     6181 tatcgatttc ttgacctttt tcaataaatg ccatcttatt ctcctaacgt tttgtaaatt
     6241 tctctgacaa gagcttctgt gttatcccaa cccaggcaag ggtctgtgat agacttacca
     6301 aataattctg gctcattttg tcgaccatct tccagataag actcaatcat aaaaccacga
     6361 acgaactgct taattttttc attccaagca cggttaatca aggtctggcg gacaattcgg
     6421 atctgttcaa tatactgctt accagaattg tcatgattgg tatcaatgat gataaaagga
     6481 ttttccaagc ccattttctc atactgggca atggtatcaa ttaaattgtc ataatagtag
     6541 ttgggaatat tttttccata ctcattaaga gcaccacgaa gaatagcgtg tgaaagcggg
     6601 ttcccagttg tttctacttc ttttcctaag aaaaggaaac tttgtttgtt ttgagcagca
     6661 taaatcccat taaacatgac attgagattt ccagaggttg gatttttaaa accagtagaa
     6721 aatcctgccc cacttgccac aaagcggtgt tgctggtctt caactgaacg ggcaccaact
     6781 gccatgtaag aaatcaaatc atctacaagc ggaaggtttt caggataaag catttcatca
     6841 gcagttgtca tccctgtttc tgtgatgaca cgatagtgaa gatggcgaac ggctttgatt
     6901 ccattgataa gactaggcgc ttctgtcgcg ttaggctggt gaatcaagcc cttatagcca
     6961 tctccgttgg tacggggttt ggcagtataa acacgcataa ccataaagat acgatctgcc
     7021 acttcttctt gtaggactgc caaacgctta gcgtattcaa ggacagcttc ttcgttgtca
     7081 gatgagcatg gcccgattac caagagaatt cgctggtctt ctccacgtat aatggcttct
     7141 agctcttgat ctcgctgtga tttcctctcc aaagcctgac cttctaattt tgacaaggca
     7201 cgaacttctt ctatatttat tttagagctt tttgctgtaa ataccataac tcatctcctt
     7261 ataaagcaaa cggataccca gtaaaaattt acttttcaca agatatccgc ctctaaacta
     7321 tctcatttta ttgtctttta ccgtgacagt ttttaaattt cttaccagaa ccacatgggc
     7381 aaagttcatt gcgtccaatc tggctcaaat ccaaatcttc tggcatactt gcttggtgag
     7441 cagcgatatt gcgagtcgct gttgtactga tatgacgttc tgcctgtggt ctttcttgtt
     7501 catgaatttg tgctttcatc atcaagcgtg tcacatcaaa ctcaatcgaa ccaatcatat
     7561 cattaaacat acggaaacct tctgcctgat actcaacaac agggttgttc tgagcatagc
     7621 cacgaagtcc aaccgcgtta cgcaattgat caagggcatc gatatgatct gtccacttgt
     7681 tatccaccac tcgtagaatc aaaacttttt ggaattcttt aactgcttct tcatcgcgta
     7741 gttttgaaac ctgactatcg taaaccttca aggcacgttg gaaaagctct tccttgatgg
     7801 ccttatcaga caagcctgac aagtcttcca tcgtaataga atcttcagga agcaagttat
     7861 acttagcgaa gttcaaaatt gcctctagtt tctcatcttg tttagcacgc gcatgaccgt
     7921 caacgacacg accaatcgtg cgtttgatca ttgcctgaat ttcaggtgcc aagtcacggt
     7981 ctgcagtaat gacatcataa cgttgagtat agataatctc acgttgttca cgcatgacat
     8041 cgtcgtattg aaggacttgt ttacgggtat cgtagttatt tccttcgaca cgtttctgag
     8101 ctgcttcaac ctgacgcgtc aacatgcgag actcaatcgc ctcttcagac atgttcaagc
     8161 gttcaaagat tcccttcaag cgttcagaac caaaacgttt catcaaatca tcttcaagag
     8221 ataggtagaa ttgtgactca cctggatctc cttgacgacc tgaacgtcca cgaagctggt
     8281 tatcgatacg acgactttca tgacgttctg taccaataac acaaagtcct ccaagttcac
     8341 gaacaccttc accaagcttg atgtcggtac cacgacccgc catgttggtt gcgatggtaa
     8401 cggcaccacg ttgaccagca ttcatgatga tttgggcttc tctatagtgg tttttggcat
     8461 tcaagacttc gtgaggaaca ccagctgcaa ccaatttctt agaaatgtag tcactagttt
     8521 caaccgctac tgtaccaacc aagacaggtt gacccttttg gtaacgagcc ttaacgtctt
     8581 cgacaaccgc tttaaactta gattcgatac ttgcataaag aaggtctgag tggtcaatac
     8641 gttgaacagg acggtttgtt gggattggaa taacacgaat gttgtagatt tcacggaatt
     8701 cttcttcctc agtcttacct gtacccgtca taccagacaa tttcttgtac atacggaaaa
     8761 ggttttggta cgtgattgag gcagatgtct tggtttcatc ctggattggc acaccttctt
     8821 tggcttcaat agcttggtgc aatccatcag aataacgacg accttccatg gtacgacctg
     8881 taaattggtc gacaatcaag atttcttgct cttcgctcac cacatagtca atatcgagaa
     8941 gcatgatgta gttggcacga agggcgttat cgataaagtg ggtcaaagcc acgttttcga
     9001 tgtcatagag gttttcaagt ttgaagtagc tttcagccct gtcaatccct gaatcagaca
     9061 aaccaatagt cttagactgc acatcgatga tgtagtcatc tttgttcaaa gattttacat
     9121 agtggtctgc catgtgatac aactgactgg tttcaaccgc attggcacct gatacaatca
     9181 aaggtgtacg agcctcgtca atcaagatag agtcaacctc atcgaccaag gcatagttaa
     9241 gcggacgttg taccatgttt tcagcgcgaa cgaccatgtt gtcacgaagg tagtcaaatc
     9301 cgatttctga gttagttgag taagtaatat cacactcata ggcttctttt ttctccattg
     9361 gagatttggt agccaagtta atccctactg acaaaccaag ccaagagtac aattcaccca
     9421 tctcagtcgc gtcacgttct gacaggtatt cattaaccgt aactacgtga acccctttac
     9481 ctgaaagggc attgaggtat accggcatgg tcgcagtcaa ggttttccct tcccctgtac
     9541 gcatctctgg cacgtcacca tggtgaagaa caatcccccc catgacctga accttataag
     9601 ggaagagacc taggacacgt ttggcacctt cacggacaac cgcaaatgct tcgtaaagca
     9661 atgaatccag tgattctcca ttttgataac gttccttaaa ttcaactgtt tttgctttta
     9721 gttggtcgtc agtcaaagca gccatttggt cttcgtattt gaaaaccttg tcagccatct
     9781 tttccagacg acggatttct cctttatcat tttcgataat tgtttttaaa atattagcca
     9841 tgtttttcct tactttaaat tccgaatatt ttagaatgtt cctttaattt tagcacaatt
     9901 actgattatt ttcaaggaag aatccccatt ttgaaaagga aaaagaggtt agtttccaag
     9961 ctaacctctc tgacttttat gatactttaa ttgccaagaa tcggcaaaat agcaaatagg
    10021 ataaataagt taatccaaag agaaagacag cagatcaatc caaaaacaaa gagactgact
    10081 ttcttggaca gcaaggccat caaaatggac agaatgccaa aaactagcaa gactttctgt
    10141 atgctgaaga ggtcaatctt cccccccaga atcggactgc cccaaggaag aaagaagaaa
    10201 gcaatccaga tcaacagaac taaaccaata tagaccttag aatagcgtgt aataaatgat
    10261 tttagattca acatcctata gctccaatcg tttcaaaata aactctgata gcatccgcaa
    10321 cccataaggc actttctggt atccaacgtc tgttaacttt tataaaatcg actaactgac
    10381 gattacactc acaattagct ccaataccag ctccccactt gtaacatcta tcatgatttt
    10441 ggcaaccttg atccaaaacg tctaccacag gtaaagtaaa tccttccccg ttgtaaccag
    10501 gaccacagta attcccgtga acaggcaatc ctgccttaaa atatttagca ggtgtaaacg
    10561 tatttgaact atagtcttcg cttattgtct ctaccaataa acccatgtca attacatctt
    10621 tcgcttgttt atcttgaacc gctttatcat aatcaaaata aatcctatct ttatctttta
    10681 caagataact cttcaacaat tctccgttac gaaaacttct atcgctaact tccaaagagt
    10741 ttaagttatc atgtgaatta gagtctgcaa aaacattttt tccagcaaat aaaagtaaaa
    10801 aggcagataa agcaactaaa caaattttaa cgatagtttt catgactact cctcctaata
    10861 aacataagtt ataagctaaa tacacaaaca atatttttac caaaagaaag ttaatttttg
    10921 gtaaatgtac taaatacaca taaacttaaa gcttgtcaaa tgagtttaag aaatacatgt
    10981 tttatattat tctaacagat gatatttcat atgttctcct ccttacctat aagctataaa
    11041 atatttaagt ttggctataa taaaactaca aaaaataagt atgtcaaact taactaaaga
    11101 atataaataa cacatcaatt agtcactccc aaaaccatat atcaaaccat ggtattaaag
    11161 gctcccaatc attacaatat ataacaaaat taagtgaatc ttctatttcc atgacttttc
    11221 cctccttttt gatataataa taccaccttt ttctacgttt tttataaatg tagaaaatat
    11281 tcacatttac ctaggaggaa caatatgaga tgggattatg gacagatttt taaagaaatt
    11341 cgaaagtcaa aaggattgac ccaacaagat gtatgtggac aagtcataca tcggacaact
    11401 ctaacaaata ttgaacacgg taaagttatt cccagttttg aaaacatggt atttcttctt
    11461 gaacaaattg atatgagctt ggcagaattc aagtatatat ggaacgaata ccatcctagt
    11521 aaaaggcgag atattattgt agagagccaa aatccgtcta cttttcaaga tactagaaaa
    11581 atggttgaac tcactgagaa atgtcaaaaa tatcttaaga cacatcacga tgttcctatt
    11641 caaaatatct atcgtcatac aaaaattgtc acagagttac gaactaaagg attcaaaaac
    11701 aaccacgtct tgaaagattt gtctgaagaa atttgggact atcttgaacc tatggataca
    11761 tggtacatta gtgatttgaa attgcttgga accattctct ttttctttcc ttctgaaaat
    11821 cttccccttc ttattgatag aattatgaaa accatcgaga aatataaata cttccgagaa
    11881 acaaaagtat ttttatcatc ttttttagcc aatctctcca ctgtatattt tcaacatcat
    11941 ttattcaaag aatgtgaaac aatcacccta caacttttgg tattagcaga agaattaaaa
    12001 atatacgata ttcttggatt ctctcaagta cgcttgggaa tactacaaca taactccgat
    12061 ttgattgata aaggaataac tttattacga ctaaccaaag aagaggcatt agttgaaata
    12121 ctcgaaaaag aaattaatga tttttcaaac ctataatttg taataactct catcatttta
    12181 ttatagtaga ttgtaataga atatgaacga atcaattagg ggatctaaag cattttatac
    12241 caatgtttta taagttgtat tgtattattc catattcaat ccactataca agatgaatat
    12301 ttctctcaag tttcataatc aaaataaaaa tgactgtatc tatagctcca taaacaaatc
    12361 atagatacag tcatttttta gttcctacac cttcctttat gcacaccttt agacttccct
    12421 agttcccgtc tcaagtcaag catttttttg aaaaagacat aggctaacca atcactagca
    12481 aaagcgataa gtagtaataa tagccaaata ccccataact tgatatctgt caaatttctc
    12541 aagacgatat tgaaaaacag aactgaaaaa actgtccaag caaggctaaa aagagcatag
    12601 agggtgatgt aaatccagta aaaatagtaa aaaattggga aaaatttact ttctctatta
    12661 tccttgtcaa tccagctgaa aaagtaaaaa cagggtaata agattatcat tttaaacaag
    12721 tgttccatca caaacctcct cttttaaatt gttttcttta gtttcgttct attaaatgtt
    12781 attaccaata taaaccttgg aatagcgtgt aataaatgat tttagaggta ccataaggcc
    12841 acctcctaca aatagaaacc gatataaatc aatgccttcc acccttagac ttccctagtt
    12901 cctgtctcaa gcgaaacatt tctttgaaac aggaataagt taaccaattc ataccaatag
    12961 ctagcagaat aaaaagaaac caaatgcccc ataacttgat atctgtcaca tttctcaaga
    13021 cggtattgaa aaacagaact gaaacaactg tccaagcaag gctaaaaaga gaatagaagg
    13081 ggatgtaaaa ccagtaaaaa taataaaaaa ttggaaaaaa cttactattt ctgttggcct
    13141 tctcaatcca gttatcaaaa taaaagtacg gtgctaaaag taagaattta aacaaatgtt
    13201 ccatcaccga catcaccctc tttcttttga tagcgttttc tattatttta ttatatcaaa
    13261 aaaatccgga actgtcattc cagattctac ttttttattt gcgttttctt gcgatgagat
    13321 gaatcggtgt tccctcaaaa acaaaggcct tgcggatttg attttccaag aaacgcaggt
    13381 aagaaaagtg catgagttct tcttcattga caaagatgac aaaggttggt ggtttggttg
    13441 ccacttgggt cgcatagaaa atcttgagac gttttccttt gtctgtcggt gttgggttga
    13501 tggcaatggc atccatgatg acatcgttca agacagctga tggaatacgt gtattttgac
    13561 tttcgctgat ttgcttaatc atctcaggaa gtttgtggag acgttgcttg gttaaagctg
    13621 atacaaagat aatcggtgcg taaggcaggt attggaactg ctcacggata tcttcttccc
    13681 agtttttcat agtgtggtta tctttttcaa gcgtatccca cttgttgacc acgataatca
    13741 tccctttacc agcttcatgg gcaaatcctg cgatacgctt gtcgtactca cgaatgcctt
    13801 cttccgcatt gatgaccatc aagaccacat ctgaacggtc aatagcacgc atggcacgca
    13861 taacagagta tttctcagta ttttcataaa ccttaccaga cttacgcata ccagccgtat
    13921 caatcatggt aaactcttga ccatctgtat ctgtaaagtg ggtatcaatg gcatcacgag
    13981 ttgttccagc aacaggacta gcaataacac ggtcttctcc caagatagca ttgatcaagc
    14041 ttgattttcc aacgttagga cgaccaatca agctaaactt aatgacatct ggattttctt
    14101 cctcatattc atttggaaga ttttctacga tcgcatctag cacatcccct gtaccgattc
    14161 catggacaga tgagataggc aatggttcac ccaaaccgag agcatagaaa tcatatatat
    14221 catttctcat ctcagggttg tccaccttgt tgactgcgag gataactggt ttgtgggtct
    14281 tataaagctt acgagctacg tattcgtctg catcagtaat tccttcctta ccagacacga
    14341 caaaaacgat aacatctgct tcttccatgg caatttctgc ctggtgcttg atttgttcca
    14401 tgaaaggagc atcgacatca tcaattcctc ctgtatcaat catgctaaaa gaacgattga
    14461 gccactcacc cgttgcataa atacggtcac gtgtcactcc ttcgacatct tctacaatgg
    14521 agattcgctc accagcgatc cgattaaata gggttgattt cccaacattg ggacgtccta
    14581 caatggcaat agttggtagg gccataattt ctcactttct acaataattt cttttgttca
    14641 agattttttc tagttgagct tggttcagct tgaccaaact gttctgctag gcgctgactc
    14701 cagcttgtgg tcgcacgcgc cccagcatag tcagcctgaa cacggtcata agcttggatt
    14761 gcctcagttg actgttcttg gtattcttcc tcaaagacaa cattctctag tggcagtctc
    14821 ggtttcatat catgatgttg atttggcaca cccagtgcca tcccaaagac agaataggtg
    14881 tagtcaggta ggttaaagag ctctgccact tcttcagact tgtatcgaac caaaccgata
    14941 atcacaccac catagcccaa gctttcagct gccaacaagg cgttttgtcc agcaagagct
    15001 gcatcgaccg aactaatcaa gagaccttcc acaccttggg gttggaaggt gtcggtatga
    15061 agtcgggctc ccttttctgc tcggttcaaa tctccgacaa agagaaggaa aacagcagac
    15121 tggcgaatgg cttcttgagg taccaattta tacaaggcat ctttcttctc ttgacttcgt
    15181 accacaatca cagagtagga ttggaaattc ttccaagatg atgccatctg ggctgctgtc
    15241 aaaatctcat ttaagtctac ttggggaatt tcttgctctt taaacctgcg cactgaagta
    15301 tgagccttca tcaatttaat ggtttctgtc atcgacggtt tactccttct aaacgagtct
    15361 cctcagccaa ataacggatg cgttccatga cgcgtctggc ttcccaggtt tcgtcatttc
    15421 catttttccc tttagcaaaa tgcttctcca aatcttcaaa gttgaagttg gatgtgaaaa
    15481 aggtcggtaa attttcctgc atccgatatt ggagaatgac ctgcaggatt tcgtcacgca
    15541 cccaaacggt tgattgctcg gcgccaatat catctaaaat caggacctca gacagcttaa
    15601 tctcatccac caaggtctta acattgccat cactgatagc atttttgaca tcaatgacaa
    15661 agctaggata gtggaggaga gttgatgaaa caccacgttt ttctgataaa tcatgagcta
    15721 aggccgccac catgaaactt ttacccacac caaagtctcc atataagtaa agaccttttc
    15781 gaatagctgg atattgctcc acgaaggcta gtagcttttc aaaaactggt aagcgcccca
    15841 aatcatccaa gtcaacttga gccaaactag ctttcttgag actggctggt agattgatta
    15901 acttgagacg gttcttaata gccgcttctt tttcagccgc gattagctca ggagtttctt
    15961 catatgaaac atctgcatag ccatgattct taaccaaaat cggcttgtag cctttggcaa
    16021 tataatccgt atccccacgg agaaacttgt cacgctcggt gatgtactga ttaaacttgg
    16081 agatactgcg atttaattcc tctggagtca aggattcttg ctggataaaa gccgcaacat
    16141 cagggtcctt catgattttc tggaccaaat cttgataata aaaacggctg ggttgacgtt
    16201 tgagtacgtc tccgacactt tccatctaat ctcctccttt ttctaatcga gctaatagtt
    16261 cttgcttctt acgttctagt tccagacgag tttcctcgct ggtttcattc ttatattcag
    16321 gattactcca tttaggaaca ttggttttta ctggggcagt ctgattctgt ttttgtattt
    16381 ttgctttctg tcctcgctca cggatgcgca agactgcctt ttctgccgaa tgaatctttt
    16441 gataggcata gtcattggct accttcatgg catatttctc attgatattt gccgaatcga
    16501 ccttattaaa ggtcaataaa agaatgatat tgatgacttc gtccagcaag cccaagccag
    16561 ccatctgttg caagagttct ctttctgttt gggtaatggt tcccttgcgt gtttgcttga
    16621 tttctgccaa gaactgcagg gcagttttac ttttggcttc tttgataatg gttgtttcct
    16681 taagactaaa gtcagaggaa actggttttt gagcaatttt ttcacgcatg cgtttggttg
    16741 aaataacctg agaaacagct gttgacttgg ccaattgata ggtttcaaac caagtccatt
    16801 tcttctcctc ggcaatagca aagaggttta agacatcgga ctgctcatcc gcaaaacgaa
    16861 gtccatctcg agccatcagc tggcgaaaat ggtccaagtc aaaatcgttg gccactttct
    16921 tcttgagacc aaggtcttct tgactgccta gttctgccaa ttctggaaag acttgattga
    16981 gtgagacagg tatttcttca ccatcagcac tttcaacttt caaatcctcc acagctacat
    17041 cgccaatctt tttctctaag agtctgcgat aaacaggatg ctccaagaag tcttgactag
    17101 atagaggagc atggaggact agctgataaa catccccctt ttgatagagg gtcaagagat
    17161 taaaagcaga taagattttc aatgatttta tcagtctatc catcccaaag ttaagatggt
    17221 tgagaatgct tgaaaaaaga tattcctttc taccattatc ccaaaaactg attgtataaa
    17281 gataaaggct cagtgcctcc tgaccgataa tcgggaggta gcactgtacc agagatgagg
    17341 tatcttgcga cacccgatta ttctttagat aagaaaaacg gtcaattggc ttcatttatc
    17401 tttccttttt ctttttagag gactgggtga tttgttggag caagctctct aactcactga
    17461 catccttaaa actacgatag acactagcaa aacgtacata ggtaatctcg tccaattcag
    17521 ccaactcctc catgacgagt gaaccaatgt cctcactttg aatttcattt tcatttcgac
    17581 cacggagttt ctgttcgata cgattgacta ccatgttgat ttcatcactt gacacaggac
    17641 gtttctgggc tgagcggata atcccattaa agattttatc tctggagaat tgttcccgtg
    17701 tgccatcttt tttaacaacc actaaggttc tttcttctac tcgttcgtag gttgtaaaac
    17761 ggtgttggca ttcgtcgcac tcacgtcttc tacgaatggt gttcccttct tctgcttggc
    17821 gactatcgat aacacttgac ttggtagccc cacattttgg acaacgcatc ctttccctcc
    17881 ttatcgtttt cttttcatta taccattttt taagcgattc ccaaaacaat tcttcttttt
    17941 gcttgacaag ttttttgttt tgttgtatta tttaattaag acaaaagggt aaaagaaagg
    18001 agactaagat gtcctggaca tttgacaaca aaaaacccat ctatttacag attatggaga
    18061 aaatcaagct tcagattgtt tcccatacac tggaacccaa tcaacaactt ccaaccgtga
    18121 gggagctagc tagcgaggct ggtgtcaatc ccaataccat ccaaagagcc ttatcagacc
    18181 ttgaacgaga aggatttgtc tacagcaagc gaacaactgg acgatttgtg actaaggata
    18241 aggagctaat cgctcagtca cgcaaacaat tatcagaaga agaattggaa cacttcgttt
    18301 cctccatgac ccattttggc tatgaaaaag aagaactacc aggcgtagtc agtgattata
    18361 ttaaaggagt ttaagcctat gtcattacta gcatttgaaa atgtatccaa atcatatgga
    18421 gcaacaccag cccttgaaaa tgtttctctt gacattccag ctggaaaaat tgtcggcctt
    18481 cttgggccaa acggctcagg aaaaacaacc ctgattaaac taattaatgg cctcttacaa
    18541 ccagatcaag gacgtgtcct catcaacgac atggacccaa gcccagcaac caaggccgtt
    18601 gtagcttatt tgcctgatac gacctatctc aatgagcaaa tgaaggtcaa agaagcccta
    18661 acctacttca agaccttcta taaagatttc aatcttgaac gcgcccatca tctacttgca
    18721 gacctgggca ttgatgaaaa tagtcgtctc aagaaactat caaaaggaaa caaagaaaag
    18781 gttcaactga ttttggttat gagccgtgat gctcgtctct atgttttgga cgaacccatt
    18841 ggtggggtgg atccagcagc ccgtgcttat atcctcaata ccattatcaa caactactca
    18901 ccaacttcta ccgttttgat ttctacccac ttgatttctg atatcgagcc aatcttggat
    18961 gaaattgtct tcctaaaaga cggaaaagtc gtccgtcaag gaaatgtaga tgatattcgc
    19021 tacgagtcag gtgaatccat tgaccaactc ttccgtcagg aatttaaggc ctaagcaaag
    19081 gagattattt atgttttgga atttagttcg ctacgaattt aaaaatgtta acaagtggta
    19141 tttagccctc tacgcagccg tgctagtcct ttctgccctc atcggaatac agacacaagg
    19201 ctttaaaaat ctaccttacc aagaaagtca ggctactatg ctactttttc tagccacagt
    19261 ctttggtggc ttgatgctta cacttgcgat ttcaaccatt ttcttgatta ttaaacgctt
    19321 caaaggtagt gtctacgacc gacaaggcta tctgactttg accttgccag tttctgaaca
    19381 ccatatcatc acagccaaac taatcggtgc ctttatctgg tcattgatta gcaccgctgt
    19441 attggctcta agtgctgtta ttattctggc tttaacagct ccagaatgga ttcctctttc
    19501 ttatgtgatt acatttgtag aaacacatct ccctcagatc tttcttacag gtatatcctt
    19561 cctactaaat accatttcag gaatcctctg catctacctg gctatttcca ttggacagct
    19621 tttcaatgaa taccgtacag cactcgctgt tgcagcctac attggtatcc aaatcgtcat
    19681 tggatttatt gaacttttct tcaatcttag ttctaatttc tatgtcaatt cactggtagg
    19741 actcaatgac catttctata tgggagcagg tatagccatt gttaaagaac tcatattcat
    19801 agctatcttt tatctcggaa cctactacat cttgagaaat aaggttaatt tgctttaaat
    19861 aatttttacc tagatatgta acatactcat agaacaaaag aaaccaggca aaaagtcttt
    19921 aaaattagaa aacgcatagt atcaagtgtt aaaaatcctt gatattatgc gttttttgtg
    19981 agctgactta tttcctttca ctatatcgca aaatgaaata agaacggaac gatgagattt
    20041 tggaattcaa atcaatttat aagaatgttt tagaagtaat attatcctat tccagattca
    20101 gttcactata caattgagtt ttcaagcaac ctgtttacat aatgtgtaca taattaggtt
    20161 cgtgattcca cccttttcac ctttaaaaac ctcgctttcg caaggctctt ctatttataa
    20221 gataaggcac gtttaaaggt tttccaaatc cctaaatcat ccgtttgaag aacgagacta
    20281 gcatacatgc gtccgataaa tcctgttgct accaccgcaa aaatcactgt aatagcaagt
    20341 gaaatccatg cttctgctcc ccccgcatag tcattaatcg ttcgaaacgg cataaagaag
    20401 gtcgaaataa agggaatata agaaccaatc ttcaagagga gattgtcacc agctgcacct
    20461 agagctgtca ctccaaaaaa accacccata atcaaaatca tcaaaggcga caaggctttc
    20521 cctgagtcct caggacgaga aaccatagat cctaggaagg ctgccaagac tacgtacatg
    20581 aaaagactga tcaaaataaa gagcaaggta ttcagtgaga tagcatctcc caagtgaacc
    20641 aaaataccag actgagccaa gaatggcaaa cctttaaaga gcaaaacggc agccagacca
    20701 cctacaacat agatcccaat atgcgttaaa atcactagaa acagagccat catccgcgca
    20761 tagaaatagt gacttgccct tatgctagaa aaaacgactt ccataatttt ggtgcctttt
    20821 tcactggcaa cttcctgagc tgttacaccc gcataggtaa tcagaatcat ataaagaaag
    20881 aatcctaagg cacctgctgc aattgtttga ataaactttt tattttcctt gacttcatca
    20941 atcttttctg tgaattgaat tgtctgcgct aagcgttttt cctgctcttg agacaaggaa
    21001 gcagttgaac gattaagctg attttgcagt tcattgagta tacctgtaac ctcaaattta
    21061 attccatttt caagcgatgt ttcgccatga taaactgcct ttagaacact atcttcttga
    21121 tcaatggtca aataaccttt taatttttct tctttaattg cttctttggc acttgcttca
    21181 tctttatagt cgaagttaac accatttaca ttcttcagtc cttctgctac agatggcact
    21241 gttgtcacta ctgccacttt attattttta gccatagaag aaccttggag atgcccaatt
    21301 cctacagaga ttcctaaaaa gaggaacggc gaaatcacca taaagaagaa actccatgac
    21361 tcgacatgtc gaagataggt ttccttgatt acaacccaca tatttctcat acttccactc
    21421 ctgattctag tttaaagatt tcatcgatag ttggcgcttg ttggtcaaat gttgcgatat
    21481 attgaccttg agtcaagatt gggaagagtt cccttccagc gctctcatcc tccaaaatca
    21541 atttccaact gccttgtttg gtcaagctca cctgtttgac atgaggaaga ttttccaatt
    21601 cttccttgct tcgttcactt gaaacaaaga gacgcgtttt cccgtattga ttgcggacat
    21661 cctgaactgg tccgtgcaag accacacggc catctcggat catcagaata tcgtcacaaa
    21721 gttcctcaac attggtcatg acatggtcag aaaagataat ggttgctccg cgctcttttt
    21781 cctgaaaaat gacttgtttg agcaattctg tattaactgg gtccaatcca ctaaaaggct
    21841 catccaagat aatcaggtct ggttcatgaa tcagagtaat aatgagctga atcttctgct
    21901 gatttccttt tgacagactc ttgattttat ctgtcagctt tcctttcact tccaacctct
    21961 tcatccattg agggagtttt tctttgactt ctttggcatc catgcctttt agagtcgcca
    22021 agtagcgaac ttgttcaaga actgtcaatt taggcatgag actgcgttct tcaggcagat
    22081 aaccaatccg agcataggtc tcctgacgaa tatcctgacc atccagaccg atttctccct
    22141 gatattctag gaatttcaaa atactatgga aaatcgttgt ttttccagca ccattttttc
    22201 cgactagtcc caaaatacga cctggtcgcg cttgaaagtc aataccaaac aaaacttgct
    22261 tggatccaaa acttttctct agacttctta cttctagcat ctttcacctc cgaaatttct
    22321 tgcactcatt atactccttt ttgatagcct ttacaatgtt ttttgtccat ttttagaaga
    22381 ctattgctgt gtaaaatatg gcctggagca cttttatact caatgaaaag caaagagcaa
    22441 actagaaagc tagccgtagg ctgctcaaag tacagctttg aggttgcaga taaaactgac
    22501 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaactat
    22561 atctacggca aggcgaagct gacgtggttt gaagagattt tcgaagagta ttagtgataa
    22621 atccattata cagtagcaaa cttaatttat accttccgct cctcaactgt ctatttttaa
    22681 tcctgaattg ttatttgagt aactcctttt tcctcataaa gttttcttcc tctaaaactt
    22741 ctggaaaaag gcgaatagtt tcagacaaca tttttataag aaacaagttc atctgtcatt
    22801 tcaagaagga gtaatccttt atctactaat ggacggaaca gaattcaacc gcttgtccca
    22861 tatgttttct aaggattata tagtaaaatg aaataaaaac aggacaaatt gatcaggaca
    22921 gtcaaatcga tttctaacaa tgttttagaa gtagatgcgt actattctag tttcaatcta
    22981 ttatatctat tatgcacacc actataggat ctaataaaaa tcacaacaag ttcattcata
    23041 gatggttacc tcagggaact aagaaaacga ctacaaagga agtcgcattc atcgaaaagt
    23101 ggattaacaa ctatcctaaa aaatgcttga actacaagtc ccccagagaa gacttctgga
    23161 tgactaactt gaacttgaaa tttagcaata attaattcac catctaacta tatttagtaa
    23221 ttatttcaga actgattaat attaaaatta actaacaatt caaaggattc atactagcca
    23281 taaattacgt ccatcagaga gagactctta ctacttttag attttagtct ttctagcttc
    23341 agaatacatc taaactttag ggaaaatgac tattcgaaag cgcgaatgcc tcaaaattat
    23401 ctcagataag ctattcgaaa cttagaatgc ttttaaattt atggaattgc gattattcga
    23461 aacctagaat gcatataacc tttagttgac agacctattc taagtctcga agggctattt
    23521 actttctatt ccttatcaaa aaagactcat tccccctttc tcctccaaaa tatggtatag
    23581 tagaaatata ctatctatga ggagtttaca tgtcacagga taaacaaatg aaagctgttt
    23641 ctccccttct gcagcgagtt atcaatatct catcgattgt cggtggggtt gggagtttga
    23701 ttttctgtat ttgggcttat caggctggga ttttacaatc caaggaaacc ctctctgcct
    23761 ttatccagca ggcaggcatc tggggtccac ctctctttat ctttttacag attttacaga
    23821 ctgtcgtccc tatcattcca ggggccttga cctcggtggc tggggtcttt atctacgggc
    23881 acatcatcgg gactatctac aactatatcg gcatcgtgat tggctgtgcc attatctttt
    23941 atctagtgcg cctatacgga gctgcctttg tccagtctgt cgtcagcaag cgcacctacg
    24001 acaagtacat cggctggcta gataagggca atcgttttga ccgcttcttt atttttatga
    24061 tgatttggcc cattagccca gctgactttc tctgtatgct ggctgccctg accaagatga
    24121 gtttcaagcg ctacatgacc atcatcattc tgaccaaacc ctttaccctc gtggtttata
    24181 cctacggtct gacctatatt attgactttt tctggcaaat gctttgacac gtaaaaaatc
    24241 cgtttggttt cccaagtgga tttttaaagc gtagattaac tatagcttga tactaaatat
    24301 actttggtat ggaaatcatg catatttttc gatagtgagg cgaggactta cctagccttt
    24361 ccgccgtgat agaaacacct gaaatctaat ggtttcaggt attcggaaac tttgagacac
    24421 taggctcaaa gtttaggtat ggaatttcga agaaagtcgc taccgtccgt aatcacttaa
    24481 ggaaaggctc aaaaatattg ttttcaacca caaaatccgt ttggtttccc aagcggattt
    24541 tgtgctttat tttgaaactt cttttgcaag aacaaagttc ccaagtgtgg cagaaccatt
    24601 tcctgcgact gctggcgtca cgatatagtc acgcacatct ggtactggta ggtaaccatt
    24661 aagaagagat gtaaatttct cacggacacg gtccagcata tgttgttgag ccatgacccc
    24721 tccaccaaag acaatcacgt ctgggcggaa agtcactgtc gcattaaccg cagcttgagc
    24781 gatatagtag gcttgaacat cccaaacagg gttgttgagt tcaatagttt ccccacgtac
    24841 acctgtacga gcttccaaac ttggaccagc tgcataacct tctagacatc ccttatggaa
    24901 aggacaaaca cccttaaact ctttttcaat atccattggg tgtctagcaa cataataatg
    24961 acccatttca gggtgaccca caccaccgat aaactcacca cgttggatga cgcctgcacc
    25021 gatacctgta ccgattgtgt agtaaaccaa gttttcgata cgaccaccag cattgttacg
    25081 ggcaaccact tcaccgtaag cagagctgtt tacgtctgtt gtgaagtaca ttggcacgtt
    25141 tagggcgcga cgaagggcac caagcaagtc cacatttgcc cagtttggtt ttggagtcgt
    25201 cgtgataaag ccataagttt ttgagttttt gtcaatatca atcggcccaa atgaaccaac
    25261 tgcaagacca gcaaggttat cgaattttga gaagaactca atggttttat cgattgtttc
    25321 gattggagtt gttgttggaa attgtgtttt ttctacaacg ttaaagtttt catcaccgac
    25381 agcacagaca aactttgtac cgcccgcttc caagcttcca tataattttg tcatgataaa
    25441 cctcttgttt ttattttctt tattatagca tacttcgaaa gtctaaatgt ctctattttt
    25501 tagattttcc tctgtaaatc ttactatcta ataaaaacga acaaacatgt catttgttcg
    25561 ttttcacatt agagaggatt gattagattt tcacttcgat cacagcatcc cccttagcaa
    25621 ctgaacctgt tgcgactgga gctactgaag cgtagtcacc tgtatttgta acgataacca
    25681 ttgttgtatc atcaagtcca gctgcagcga ttttgtttga gtcaaatgtt ccaagaacat
    25741 cgccagcttt caccttatta ccttgagcaa cttttacttc aaaaccgtca ccgttcatag
    25801 atacagtgtc aataccaacg tgaatcaaaa cttcagcacc atttcttgtt ttcaaaccaa
    25861 aagcgtgccc tgttggaaag gcaattgaaa cttcagcatc agctggtgca tagaccacgc
    25921 cttggcttgg tttcacagcg ataccttgtc ccatagctcc acttgagaag actgggtcat
    25981 tgacatcagc aagagcgaca acatcaccga cgataggagt tacaagtgtt tcattttgaa
    26041 gagctgctgg cgcaacttct tctttttctt cagccacttc agcttgtttt gcagctgcag
    26101 ttgcgtctac ttcatcttcg taaccaaaca tgtaagtaag agcaaaacca agggcaaatg
    26161 atacagctac cataagaagg tattgtggaa gttgtccgtt accaacataa agcattgtac
    26221 cagggatgat ggtgatacca ttaccagtac cagcaagtcc aaggatagaa gccaatccac
    26281 caccgattgc accagcaatc aatgaaagga agaatggttt acggaagcgc aagttcaccc
    26341 cgaagatagc aggctctgta atacctagga aggcagaaag agcagccggg aaagcaagtg
    26401 ttttcagttt tggatttttt gttttaacac caaccgcaac agtagcagca ccttgagctg
    26461 tcatagcagc tgtgatgata gcgttgaatg ggttagcatg gtcagcagca agtaattgca
    26521 cttcaagcaa gttgaagatg tggtgcacac ctgacacgac gatcaattgg tgaaccccac
    26581 caatcaagaa accaccaaga ccaaatggca tgctaagaat cgcttttgta gcaataagga
    26641 tgtagttttc aacaacgtgg aaaactggtc caatgacaaa gagtccaagg atagacatga
    26701 ccaaaagtgt cacgaatggt gttaccaaga ggtcaatgac atctggaaca accttgcgga
    26761 cagctttttc aaatttagct ccgacaaccc cgatgatgaa ggctggaaga acggaacctt
    26821 gcaaaccaac aacagggatg aaaccaaaaa agttcatcgc tgttacttca ccaccttgag
    26881 caactgccca agcgtttgga agtgagccag agacaagcat cataccaaga acgataccaa
    26941 cggcaggatt tccaccaaat acacggaagg ttgaccacac aaccaaacct ggcaagatga
    27001 tgaaggctgt atctgtcaag atttgtgtgt aagttgcaaa gtcacctgga agtggcattt
    27061 caagagcgtt gaaaagacca cgcacaccca tgaagagacc tgtcgctacg ataactggga
    27121 tgattggaac gaaaacatca ccaaaagtac ggatagcacg ttggaaccag ttcccttgtt
    27181 tagcaacttc tgctttcatg tcatccttag atgatgttgg taatccaagt acaacaactt
    27241 catcgtacat tttgttaact gtacctgtac caaagataat ttggtattgc cctgagttaa
    27301 agaaagcacc ttgaactttt tccaagttct caatcacttc tttattgatt ttctcttcat
    27361 ctttgaccat gacacgtaga cgagtcgcac agtgggcaac actattgaca ttttcacgtc
    27421 cgcccaaggc atcgatgact ttttttgcaa tttcctgatt gttcatttgc aaaaatctcc
    27481 ttatataaca ttttgttctt gtttgaaagc gattttattc gcccttacga ctattatttt
    27541 atcatgtttt aaaaatatgt caagcgtttt gcataaaaat attctatcca cttagtgggc
    27601 aagctttaga ttgattgttt ttgactgttt catcaggaat tccttgaaaa ataagtttga
    27661 aaccttggtt aaaaagtatt ttatttcatt atctttcaca ttttcgtaaa aatttaattg
    27721 atttcctgta tttattttat gataatcgtt tgacagtttt tcctcttttt taacataaaa
    27781 ggcttgcatt ctttatcgaa aacagttact attaaaagtg ataagatttt tggaggaatg
    27841 aatggaatgg acaactgagc gtcgttacag actttatcaa gattggacgc aagaagaaat
    27901 tcaacatata aaggaaaata tggcacaatc tccatggcat actcattacc atgttgagcc
    27961 aaaaacagga cttctcaacg acccaaatgg cttttcttac tttgatggca agtggatcct
    28021 cttttaccag aattttcctt ttggtgcagc ccacggtttg aaatcttggg cacagctaga
    28081 aagtgatgat ttggttcact ttaaagaaac tggaatcaaa gttttaccag atactccatt
    28141 agatagccac ggtgcctact ctggttctgc catacaattt ggcgataact tattcctatt
    28201 ttatacagga aatgttcgcg atgaaaactg gatccgtcac ccataccaga tcggtgcttt
    28261 gatggacaag gagggtaaga ttacaaagat tgacaagatc ttgattgacc agccagcaga
    28321 ctctactgac cacttccgcg atccacaaat ttttaacttt aaaggtcaat actatgctgt
    28381 cgtcggtgga caggacttgg agaaaaaagg cttcgtccgt ctctacaagg ctgtcaataa
    28441 cgactacaca aactggcaag cagttggcga ccttgacttt gctaacgacc gtactgccta
    28501 catgatggaa tgtcctaatc tggtctttgt agaggaacag cctgtccttc tctactgtcc
    28561 acaaggattg gataagaaag ttctagacta cgataatatc tttccaaata tgtataagat
    28621 tggggcttcc tttgacccta aaaatgccaa aatggtagat gtgtctcaac ttcaaaacat
    28681 ggattacggt ttcgaagcct atgcaactca agccttcaac gctcctgatg ggcgtgctct
    28741 agcagttagc tggcttggtt tgccagatgt ttcttaccca tctgactgtt ttgatcacca
    28801 aggaaccttc tctttggtca aggaactcac tatcaaagac gacaagctct accagtatcc
    28861 agtcgctgct attaaggacc ttcgtgcttc tgaagaagcc ttctcaaacc gttcccaaac
    28921 caagaacact tacgaacttg aactcaactt ggaagctaat agccagagcg agattgtctt
    28981 acttgctgat aaagaaggta agggactttc aatcaacttt gaccttgtaa acggtcaagt
    29041 gacagtggat cgtagccagg ctggagaaca atatgcccaa gaatttggga caactcgttc
    29101 ttgccctatc gagaatcagg ctactactgc tacaatcttc atcgataact ctgtctttga
    29161 aattttcatc aataaaggag aaaaagtatt ttctggtcgt gtcttcccac atgcggacca
    29221 aaatggtatc ctgatcaaat ctggaaaccc aactggaact tactatgaat tagattatgg
    29281 tcgcaaaact aactgatgtc gccaaacttg caggcgtcag tcctactacc gtttctcggg
    29341 ttatcaataa aaaaggatat ctatctgaga aaaccatcca aaaagtcaat gaagccatga
    29401 gagaattagg ctataaaccc aacaacctgg ctcgtagtct gcaaggaaaa tcagctaagt
    29461 taatcggctt gattttcccc aatatttcca atgttttcta tgcagaattg attgataaat
    29521 tggaacacca actcttcaaa aatggttaca agaccatcat ctgcaacagt gaacatgatt
    29581 ctgagaagga acgcgaatac atcgaaatgt tggaagccaa tcaggtagac ggcatcattt
    29641 ctggtagtca caacctagga atcgaagact acaatcgtgt gacagcgccg attatttcct
    29701 ttgaccgaaa cctatcgcca gacatccctg ttgtctcctc tgacaactat gctggtgggg
    29761 ttcttgctgc ccaaaccttg gtcaagacag gtgcccagtc tatcatcatg attacaggga
    29821 atgacaattc caattcgcca accggactgc gccacgctgg ttttgcatcc gtactcccaa
    29881 aagctcctat tatcaatgtt tccagtgact tttctcccgt cagaaaagaa atggaaatca
    29941 agaatatctt gacccgggaa aaaccagatg ccatttttgc ttcggatgat ttgacagcta
    30001 ttctggtcat taaaatcgct caagaattgg gcatttctgt cccaaaagag ctcaaggtca
    30061 ttggctatga tgggacctac tttatcgaaa attactaccc tcaattggct actatcaagc
    30121 aacctttgga agagattgct tgtctcacta ttgatcttct cttgcaaaag attgaaggca
    30181 aggaagtcgc cacaactggt tacttcttac cagttacact attaccagga aaaagtattt
    30241 aaacacaaga aaactcagac cgattcgtct gagtttttta tgatcttaaa ttttcgagat
    30301 agcgctgggc tgtctctagg ttaaaggttt tatctgcgat aagctgctcg actaggggag
    30361 caacttcaga ttcactagcc ccagctagga gagctaggga tttggcctgt agtttcatgt
    30421 ggccttgctg gatgcccgta cttaccaagg ctttgagggc tgcaaaattt tgggcaagac
    30481 cgatggacac gataatctgg gctaattctc tggcagaagg atttcctagt agatcatgac
    30541 tgagagctac acgtgggttg aggccgatag agccaccctt agtcgctaca ggcatgggca
    30601 gggtcatctc accgaccaat tcttctcttt caaggtccag cgtccagcaa ctaagacctt
    30661 gataacgtcc atctcgactg gcaaaggcat gggccccagc ttcgatggca cgccagtcat
    30721 taccagtggc aatcaaaatc gcatcaatac cattaaaaat tcctttatta tgagtagcag
    30781 ctcggtaagg atcagcctgc gcaaactgac tagccaacgc aattttctcc gcaatctctc
    30841 gtccttgatc cttttggcgg ctcaagtagc gaaaggcgat gcgacagctt gcagtcacca
    30901 gagaatcggt cgcgtagttg gacaggattc ccatgagact ctgtccctga ctgagttctt
    30961 ctaagactgg tttcaaggct tccagcatgg tgttgagcat attggcaccc atggcttcct
    31021 gggtatcgac atgaatataa acaacgagaa agtctggttc accttttatc tgctcgacat
    31081 gcagatcacg cgccccaccc ccacgtttaa cgatagaagg ataggcttga ttggcaagct
    31141 ccaagagctc cgctttcttg ctggcaatct tctcttgcgc tagtttagga ttagcaactt
    31201 gataaagggc tacctgccca atcatctgtc gctgatggac ttgtgcagta aaaccacctg
    31261 cacgcttgat gattttgctg gcatagctgg ccgccgcaac cacagagggt tcttctgtca
    31321 catagggaac ggtgtattcc tgaccgttga caagtacctc tggaaccagt gaataaggca
    31381 gagaaaaagt tcccactaca ttctcactca gctggtctgc cacagtcacg ctcatctgtt
    31441 catccttctc cagactagct tgtctctcag gactaaggag cgcctgagct tttaacagct
    31501 cgaggcgctc ttggtatgat tttttagaaa atccattcca acttatcttc attatttttc
    31561 aaccttgcta taacggcgtt ggtggtcgag aatttcaacc aaggcaaaat cttgattttc
    31621 atagccagca aactgggcag agtttgtttc atccaagttt acttcctcaa aaaagacctt
    31681 ttcatagtct gcaacggata gggcagttcg ttggttgagc ttgttcaaac ggtctttatc
    31741 caaataagct tcatatcctt caaccaattc accactgaag aactcagcca cagctccact
    31801 tccgtaacta taaagggcga ttttatcccc agctttcaag ctatctgtat tttccaagag
    31861 agacaaaagt ccaaggaaaa gtgaacctgt gtagatattc cccacctttt gactgtagag
    31921 aatagactgg tcaaaatgct tttgcaagag gtcttttttc tcttgaggca ggctcttatc
    31981 catgattttt ttcaagcctt ttagcgctaa tttaggataa ggcaagtgga aacaaacagc
    32041 cgcaaaatca tccaaagtaa gctggtagcg tttttgatat tcaagccaag tcgttttcaa
    32101 actatccaag tattgttggg tagaatagac accatttaca taaggagttg tcgagtaatt
    32161 tggtcgccag aaatccatga tgtcacgggt ctgagctaca ttgtcattat taaaggccat
    32221 catgcgtgga ttttgtgtaa tcaacatagc tacacttcca gcaccttgag ttggttctcc
    32281 cggagtttca ataccatatt tggcaatatc actggcaatg accaatacct tggactccgg
    32341 agaattttcc acatgcaatt tggcataatg gagggcagct gtcgccccat agcaggcttc
    32401 tttaatctcg aaactacgag caaagggctg gatgcccagc aagccatgca caaagacggc
    32461 cgcagcctta ctctggtcaa ttcctgactc ggtcgccaca atgaccatgt caacttcttg
    32521 tctttcttgc tcagttaaaa tagagtcact agcactggcc gccaaggtca cgatgtcctc
    32581 agttaggggc gcaatactca attccttgag taagagtcct ttacttaatt tttcagggtc
    32641 aatccccctc gcttctgcta agtcttgtaa tttcaagaca tattgactgg tcgcaaaacc
    32701 aatcttatca ataccgattg tcatatttac ctctgtttta tcattcatgt aaaaaatcgt
    32761 tctatactat tttatcacaa atggcagtaa aagagagaaa aaagacttga ttcaccaaat
    32821 caagcctctt attggtcatc attttaaaga atgattagtt gctagagagt tcaccgatat
    32881 aagtagcttt ataagctcca ttcacagtta tcagctcctg gaggatcaaa tttcctgagt
    32941 aagtccttcc catctcatct acaaattttt gataaaactg actggtcgga atttctctga
    33001 catccttatc aaatgtcttg tcaagtgttt tactaacctt ctcagcaatc aattgatgct
    33061 cttgccatcc actttgaaac tctgagcccg aactagaaac catgactggg ataaacaaca
    33121 aggtcagtag acttacagac aataaggaaa atagtagact tcctgcaaaa ctagaatcct
    33181 agttcatgat tgataatacc aacaatcaaa ttcattcgta atccgaagcg tttacgatga
    33241 tttcgata
//
LOCUS       DBEJJE010000022        32369 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEJJE010000022 DBEJJE010000000
VERSION     DBEJJE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.22"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            146..883
                     /locus_tag="ACL3F5_001025"
     CDS             146..883
                     /locus_tag="ACL3F5_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0514849.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            880..2571
                     /locus_tag="ACL3F5_001026"
     CDS             880..2571
                     /locus_tag="ACL3F5_001026"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0514850.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            2687..3250
                     /locus_tag="ACL3F5_001027"
     CDS             2687..3250
                     /locus_tag="ACL3F5_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0514851.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALANRPKLIGGARAHYPQDAIRKS"
     gene            3272..9121
                     /locus_tag="ACL3F5_001028"
     CDS             3272..9121
                     /locus_tag="ACL3F5_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0514852.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVVTLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAQPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEP
                     KVEQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDK
                     SELNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAI
                     DALNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSET
                     ASLKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQ
                     EQINEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVN
                     TNESKQSEVNEAVEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQ
                     IKSITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDE
                     TESISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSST
                     SKDAVLAVSSIEEEIVENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDI
                     YYDFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHS
                     IFDLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEG
                     YLEGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNA
                     DIEVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVW
                     PYGAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTR
                     ISEEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNL
                     TKFTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFED
                     GSQKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELY
                     TESTYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSG
                     AVAALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLI
                     RLGSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTK
                     DYIQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFV
                     SREKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIP
                     GSEWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVL
                     SEYGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNM
                     AFERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKW
                     FKKVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADF
                     ETSYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQAS
                     RDEGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTF
                     EELQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            9182..10903
                     /gene="pabB"
                     /locus_tag="ACL3F5_001029"
     CDS             9182..10903
                     /gene="pabB"
                     /locus_tag="ACL3F5_001029"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0514853.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRSHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            10904..11521
                     /locus_tag="ACL3F5_001030"
     CDS             10904..11521
                     /locus_tag="ACL3F5_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGR0514854.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRDLILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCPYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPYGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            11571..12569
                     /locus_tag="ACL3F5_001031"
     CDS             11571..12569
                     /locus_tag="ACL3F5_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR0514855.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            12696..13655
                     /locus_tag="ACL3F5_001032"
     CDS             12696..13655
                     /locus_tag="ACL3F5_001032"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0514856.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTFGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            13752..14591
                     /locus_tag="ACL3F5_001033"
     CDS             13752..14591
                     /locus_tag="ACL3F5_001033"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0514857.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(14639..14809)
                     /locus_tag="ACL3F5_001034"
     CDS             complement(14639..14809)
                     /locus_tag="ACL3F5_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0514858.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            14930..15814
                     /gene="miaA"
                     /locus_tag="ACL3F5_001035"
     CDS             14930..15814
                     /gene="miaA"
                     /locus_tag="ACL3F5_001035"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0514859.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            15807..17045
                     /gene="hflX"
                     /locus_tag="ACL3F5_001036"
     CDS             15807..17045
                     /gene="hflX"
                     /locus_tag="ACL3F5_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0514860.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPNLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            17038..17661
                     /locus_tag="ACL3F5_001037"
     CDS             17038..17661
                     /locus_tag="ACL3F5_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0514861.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKLVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            17676..18605
                     /gene="rnz"
                     /locus_tag="ACL3F5_001038"
     CDS             17676..18605
                     /gene="rnz"
                     /locus_tag="ACL3F5_001038"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0514862.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            18626..19381
                     /locus_tag="ACL3F5_001039"
     CDS             18626..19381
                     /locus_tag="ACL3F5_001039"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0514863.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(19435..20343)
                     /locus_tag="ACL3F5_001040"
     CDS             complement(19435..20343)
                     /locus_tag="ACL3F5_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0514864.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            20407..20676
                     /locus_tag="ACL3F5_001041"
     CDS             20407..20676
                     /locus_tag="ACL3F5_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0514865.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            20676..21056
                     /locus_tag="ACL3F5_001042"
     CDS             20676..21056
                     /locus_tag="ACL3F5_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0514866.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            21145..21372
                     /locus_tag="ACL3F5_001043"
     CDS             21145..21372
                     /locus_tag="ACL3F5_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514867.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(21412..22137)
                     /locus_tag="ACL3F5_001044"
     CDS             complement(21412..22137)
                     /locus_tag="ACL3F5_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0514868.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSFSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            22299..24140
                     /gene="typA"
                     /locus_tag="ACL3F5_001045"
     CDS             22299..24140
                     /gene="typA"
                     /locus_tag="ACL3F5_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0514869.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24160..24414
                     /locus_tag="ACL3F5_001046"
     CDS             24160..24414
                     /locus_tag="ACL3F5_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0514870.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            24778..25077
                     /locus_tag="ACL3F5_001047"
     CDS             24778..25077
                     /locus_tag="ACL3F5_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0514871.1"
                     /translation="MKTKKHRLLALALISNFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            25148..27169
                     /locus_tag="ACL3F5_001048"
     CDS             25148..27169
                     /locus_tag="ACL3F5_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0514872.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEEGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGIKLLKNAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            27171..27812
                     /locus_tag="ACL3F5_001049"
     CDS             27171..27812
                     /locus_tag="ACL3F5_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514873.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDSKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            27916..29268
                     /gene="murD"
                     /locus_tag="ACL3F5_001050"
     CDS             27916..29268
                     /gene="murD"
                     /locus_tag="ACL3F5_001050"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0514874.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            29270..30328
                     /locus_tag="ACL3F5_001051"
     CDS             29270..30328
                     /locus_tag="ACL3F5_001051"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0514875.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            30338..31537
                     /gene="divIB"
                     /locus_tag="ACL3F5_001052"
     CDS             30338..31537
                     /gene="divIB"
                     /locus_tag="ACL3F5_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0514876.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            31668..31793
                     /locus_tag="ACL3F5_001053"
     CDS             31668..31793
                     /locus_tag="ACL3F5_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514877.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFLGEVLLGTGVVLLIGVACC"
     gene            31814..31936
                     /locus_tag="ACL3F5_001054"
     CDS             31814..31936
                     /locus_tag="ACL3F5_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514878.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGFGLAILALAGC"
BASE COUNT        10009 a         5768 c         7257 g         9335 t
ORIGIN      
        1 tacaacctca aagctatact ttgagaaacc tgtggctatc ttcctagttt actttttgat
       61 ttttattgag tataagaggt ctttcctaag cagttagagg agaattttgc tatactgata
      121 ctagtaagtg gtaaaggagc agagcatgac ctacacaatc ttaatcgtag aagatgaata
      181 tctggtaaga caaggtttga ctaaactggt caatgtagca gcctacgata tggaaatcat
      241 cggtcaggct gaaaatggaa ggcaggcttg ggagttgatc caaaagcagg tgccagatat
      301 cattttaacc gatatcaaca tgcctcatct aaatggcatc cagttggcca gtctggtacg
      361 agaaacctat cctcaggttc atttggtctt tttaacaggt tacgatgatt ttgattatgc
      421 cttgtctgct gtcaaactag gtgtggacga ctacctgctc aaaccctttt ctcgtcagga
      481 tattgaggaa atgttgggga aaatcaaaca aaaactagac aaggaagaga aagaagagca
      541 gttacaagat ttattgacta ataggtttga aggaaacatg gcccagaaaa tccagtctca
      601 tctggctgat agccaattta gtttaaagtc tttagccagt gacttaggtt ttagtccgac
      661 ctatctgagt tccttgatta agaaagagtt gggcttgcct tttcaggatt atctggtgag
      721 agaacgtgtt aaacaagcca agctcttgct tttaactaca gatctgaaga tttatgagat
      781 cgcagagaag gttggttttg aagatatgaa ctattttacc caacgtttta agcagattgc
      841 aggtgtgaca cctcgtcagt ttaagaaggg agaagaccga tgaagcgttc ttctctttta
      901 gttagaatgg ttatttccat ctttctggtc tttctcattc tcctagctct ggttggaact
      961 ttctactatc aatcaagttc ttcagccatt gaggccacca ttgagggcaa cagccaaacg
     1021 accatcagcc agactagcca ctttattcag tcttatatca aaaaactaga aaccacctcg
     1081 actggtttga cccagcagac ggatgttctg gcctatgctg agaatcccag tcaagacaag
     1141 gtcgagggaa tccgagattt gtttttgacc atcttgaagt cagataagga cttgaaaact
     1201 gttgtgctgg tgaccaaatc tggtcaggtc atttctacag atgacagtgt gcagatgaaa
     1261 acttcctctg atatgatggc tgaggattgg taccaaaagg ctattcatca gggagctatg
     1321 cctgttttga ctccagctcg taaatcagat agtcagtggg tcatttctgt cactcaagaa
     1381 cttgttgatg caaagggagc caatcttggt gtgcttcgtt tggatatttc ttatgaaact
     1441 ctggaagcct atctcaatca actccagttg gggcagcagg gctttgcctt cattatcaat
     1501 gaaaaccatg aatttgtcta ccatcctcaa cacacagttt atagttcgtc tagcaaaatg
     1561 gaggctatga aaccctacat cgagacaggt cagggttata ctcctggtca caaatcctac
     1621 gtcagtcaag agaagattgc aggaactgat tggacggtac ttggcgtgtc atcattggaa
     1681 aagttagacc aggttcggag tcagctcttg tggaccttgc ttggggccag tgtcacatct
     1741 cttcttgtct gtctctgctt agtgtggttc agtcttaaac gctggattgc tcctttgaag
     1801 gatttgagag aaaccatgtt ggaaattgct tctggtgctc aaaatcttcg tgccaaggaa
     1861 gttggtgcct atgaactgag agaagtaact cgccaattta atgccatgtt ggatcagatt
     1921 gatcagttga tggtagctat tcgtagccag gaagaaacga cccgtcagta ccaacttcaa
     1981 gccctttcga gccagattaa tccacatttc ctctataaca ctttggacac catcatctgg
     2041 atggctgaat ttcatgatag tcagcgagtg gtgcaggtga ccaagtcctt ggcaacctat
     2101 ttccgcttgg cgctcaatca aggcaaggac ttgatttgtc tctctgacga aatcaatcat
     2161 gtccgccagt atctctttat ccagaaacaa cgctatggag ataagctgga atacgaaatt
     2221 aatgaaaatg ttgcctttga taatttagtc ttacccaagc tggtcctaca accccttgta
     2281 gaaaatgctc tttaccatgg cattaaggaa aaggaaggtc agggccatat taaactttct
     2341 gtccagaaac aggattcggg attggtcatc cgtattgagg atgatggcgt tggcttccaa
     2401 gatgctggtg atagtagtca aagtcaactc aaacgtgggg gagttggtct tcaaaatgtc
     2461 gatcaacggc tcaaacttca ttttggagcc aattaccaga tgaagattga ttctagaccc
     2521 caaaaaggga cgaaagttga aatatatata aatagaatag aaactagcta actcccagtc
     2581 aattctggga gttttatgcg taattgggca aactttctag gttgtctatc ttgctaaaaa
     2641 caagaaaaaa cggtatgata gaagagtgac aacagaggta acagagatga acgagacaca
     2701 gattcaaaga gaaacacgtc aggtagtgga agatgtttta gaaaagacca atttgaagca
     2761 gggggccctt tttgttttag gtctatcttc tagtgaggtg ctaggtggtc agattgggaa
     2821 agaatccagt caagagattg gtgagctgat agtggagact atcttgggta ttctaggtag
     2881 tagaggtatc catttagcag ttcaaggttg tgagcatgtc aatcgggctc tcgttgttga
     2941 acgtcaggtg gcagagcagt ttgatctgga aattgtcagt gtccatccta ctcttcatgc
     3001 aggaggttcg gggcagttgg cagcctttaa gtttatgcag gatccagttg aggttgaatt
     3061 tatcaaggct catgctggat tggatatcgg agacactgca attggcatgc atgtcaagca
     3121 tgttcaggtt ccgattcgcc ctattttgag agagattggt catgcccatg taacggcact
     3181 ggctaatcgt ccaaaattaa tcggaggtgc gcgtgcgcac tatccgcaag acgctattag
     3241 aaagtcttga gaatgaataa aggagataaa agtgtttaaa aaagaccgtt tttcaattcg
     3301 taagattaag ggagttgtag gctctgtatt tcttggaagc cttttgatgg ctccttctgt
     3361 agtggacgca gccacctatc actatgtaaa taaagagatt atttcacaag aagctaaaga
     3421 tttaattcag acaggaaagc ctgacaggaa tgaagttgta tatggtttgg tgtatcaaaa
     3481 agatcagttg cctcaaacag ggacagaagc atctgttttg acagcttttg gtttgctgac
     3541 tgttgggagc ttgcttttaa tctacaagag aaagaaaatt gctagcgtct ttctagttgg
     3601 agctatggga ttggtagttc ttcctagtgc agaggctgta gacccagttg tgaccctagc
     3661 gctggctagt cgagagggtg ttgttgaaat ggatggctat cgctatgttg gttatctatc
     3721 aggtgacatc ctcaaaacgc ttggcttgga cactgtttta gaagaaacct cagcacaacc
     3781 tggagaggtg actgtagtcg aagttgagac tcctcaatca acaacaaatc aggagcaagc
     3841 taggacagaa aaccaagtag tagagacaga ggaagctcca aaagaagaag cacctaaaac
     3901 agaagaaagt ccaaaggaag aaccaaaatc ggagataaaa cctactgacg acacccttcc
     3961 taaagtagaa gaggggaaag aagattcagc agaaccagct ccagttgaag aagtaggtgg
     4021 agaagttgag tcaaaaccag aggaaaaagt agcagttaag ccagaaagtc aaccatcaga
     4081 caaaccaaca gaggaaccaa aagttgaaca agtaggtgaa ccagtcgagc caagtgaaga
     4141 cgaacaggca ccaacggcac cagttgagcc agaaaagcaa ccagaagctc ctgaagaaga
     4201 gaaggctgta gaggaaacac cgaaaccaga agataaaata aagggtattg gtactaaaga
     4261 accagttgat aaaagtgagt taaataatca aattgataaa gctagttcag tttctcctac
     4321 tgattattct acagcaagtt acaatgatct tggacctgtt ttagaaactg caaaaggtgt
     4381 ctatgcttca gagcctgtaa aacagcctga ggtaaatagt gagacaaata aacttaaaac
     4441 ggctattgac gctctaaacg ttgataaaac tgaattaaac aatacgattg cagatgcaaa
     4501 aacaaaggta aaagaacatt acagtgatag aagttggcaa aacctccaaa ctggggttac
     4561 agaagctgaa aaagttgcag ctaatacaga tgctaaacaa agtgaagtaa attctgagac
     4621 tgcaagtctt aaaacagcaa tttctagatt aaatacagat aaagttgaac tcgaaaatca
     4681 acttaagatt gcacagggaa aaactgaaac tgatttcagc atggaatctt ggactgtttt
     4741 gagtacagct aaaaataaag ctcaggaagt aaaagataac ggaacagcga cccaagaaca
     4801 aataaacgaa gcagagaaaa gtttgaaaac agcccttgct gacttatctg ttgacaaaac
     4861 agctttggga agcgctatcg atacagctac caagaaaaat aaagagaact atacaaatca
     4921 aacatgggca gagttagaaa cagcgcttac agcagcaaaa tctgtaaata ctaacgagtc
     4981 taaacaaagt gaagttaatg aagctgttga aaaattaact gcaactatgg aaaaattggt
     5041 tgaattgtct gaaaagccac gtttgactct atctattgaa aagagagaca tagatcgaaa
     5101 agctacggtc acgtatactt tggaaaatcc agcaaatact caaataaaat caataactgc
     5161 aactctgaaa aaaggagagg aagttgttaa ggattttgtt ttaacagaag aaaatcttaa
     5221 aactaatcat ttaactgctt tgtttgaaaa gctagactac tacaaagaat acactctatc
     5281 tacggatatg gtatataaca gaggaaatga tgatgagacg gagagtattt cagaagaact
     5341 aattcagctg aatcttaaga aactagaatt gaaagatatc cagacagtct ctctgatgaa
     5401 atttgaaaat ggtcaagaaa gtcaggttac acacttgtct gataaaccga ccgatttgag
     5461 taaattatac ttaaaagtta catcgtcaac gtctaaggat gctgtgttag ccgttagctc
     5521 tatagaagaa gagattgttg aaaataaaaa aatctttaaa attcatgcag atacaccaga
     5581 attagtagtt cgtaagaaag atggcagtct ttctaaggga tttgactatt acatggagag
     5641 agttatccct catgatggtg atatttatta tgattttaaa gacttgattt cagctatgac
     5701 atctaatcct acaggtacgt ttattttagg gagagatatt tcctcgcgta atgtaaaacc
     5761 ggatggaaat ggaaaatctt atatcaaagg tgaatttaaa ggaaaactac ttggtacaaa
     5821 tgataatgtt agacactcga tctttgactt agaatatcca ttgtttgata ctataaaatc
     5881 aggagtcgtg aaagatattg atttcaagca tgtcaatatg gtattcccag atagcaatca
     5941 aggagataac gtagcaacaa ttgcaagagt aatcaaagat aagacaaaaa ttgagaatgt
     6001 taatgttgaa ggttatctcg agggtcgaga tcatgtagct ggtttagtta ataatcttga
     6061 aggtaattcc gaaattgaaa atgtatcctt tacaggaaag attaagtcta aaggtggtaa
     6121 ttctattaca gcaggtattg caggtagaaa tatcttatct cgtgttaaac gtgcctatgt
     6181 aaatgcagat atagaggtac atcgatcatc taattctagc atgcttgttg cagtaaatgg
     6241 aataaacgca gatgcaagtg gtggttgggg aacctggggt agacttactg agtcagttgc
     6301 taaaggaaca ttagaaacca agcaaggagg gcaagctgga ggagcctctt ctacagtctg
     6361 gccttatgga gcaattgata atgttgtcag ctatgcaaaa gtgaccaaag ggaaagaatt
     6421 atttggatca gatggtgatt taaattatga ttggtttatg aaaaaaatta gtaatatttt
     6481 tggtgttcaa ggcatcagct caggcgattc gggtagtgat tctaaattta cgcgtatttc
     6541 tgaggaagaa gcaaatcaaa aagttgcttc ttataatatt acagctccca acttgatgag
     6601 tgactcaagt cttttggtag acagactcaa tgaaagttgg aaaaatactg atcaatttga
     6661 aagtatacag gattatcaag cccaaaacca attaatttac cagaacttga ctaaatttac
     6721 tccttattac aataaagaat ttattgttca tgaaggaaat gctctcactc ctgaacagga
     6781 aatattgaag actaagaaaa tcaaatcgat tgtagggttg aaaggaacag agttcgttgt
     6841 agatggcagt gatattgata ctatcatgct tcattttgag gatggtagtc agaagcgata
     6901 taaggtaacc tctactggta agttttcgat aactaattta ccggaatatc aggttgaaga
     6961 tttaaatgtg gtgtatacat cagaacatat agtacatcca ctagattcgt cactgataaa
     7021 taaccttgtt gaagaattga aaaaagtaga attgtataca gagtctactt accaagttct
     7081 aggtattgat aaagataatg ctaacaaatt gaatagaact aagagattat tcttagatga
     7141 gtcattagat gctgttaaaa cacaattgcc tacctttgta aaaacaatgt ttgaaaatga
     7201 gtggttgcac atcaatggag aatctagtgg agctgtcgct gctttacgac aaaaaatcat
     7261 ggataataag acggctatat tgcttgcttt gacttatatc aatcgttatt atgatgttaa
     7321 attctcagac tataatatta aaaaactgat gctctttaaa ccaactttcc atggtgaaaa
     7381 gattgatcta ttagatcgat taatccgact aggatcatct ggagaaaata gattaaaagg
     7441 ttcagaaaat gcagaaacgt tcaagcagtt atttgctagc gaaacgaagc agaaggattt
     7501 ggtgacttat ttagactaca atcgctcttt gttgactaat tatcaaacaa caggggaatg
     7561 gtttaaagaa acgactaagg attatattca atttgaggaa cgtccatcct tagtagagga
     7621 gattaaagat gccaaatatc gagtttacga taatttaacc gcaccgtatt atcaaggata
     7681 tatcctacct ctcttaacgt tgaagaatac tcatttagca attttatcga actatagtac
     7741 tatgacattt gtcagccgtg aaaaacgccc taattggaaa aatgaagatt ttgataagtg
     7801 ggtgaaatat gtagcaactg ctcatagaaa ccatgttgat acttggtata agattttacc
     7861 tgataatatc aaaggtaaaa tggttaaaga gaatgttact gctgtttggg aaggactgag
     7921 catcccagga agtgaatggg tagaccagaa tgctgtagat agaaaaggaa gagattacgc
     7981 cccagctcga gaattcttta atcttgtagg tggtcctatg ggaggttggt atgcttacca
     8041 tggttatggt gcgcatgctg gaggaagaaa tcgggttaat tatgaggtgt ttgatgtatt
     8101 aagtgagtat ggtatatctg tcttcactca tgaattgact cacgttaatg atacttggat
     8161 ttacttagga gggtatggta gacgtgaaaa tatgggacct gaagcttatg ctcagggatt
     8221 attccagtct cctgttccag gtcagccggg ttggggggca ctgggtctca atatggcatt
     8281 tgaaagaaaa aacgatggtg atctaattta taatgcctcc ccaactcaat ttgaaaatag
     8341 gaaagagtta gatagttata tgaaaaatta taacgatact ctcatgatgg tggactactt
     8401 ggaaggagat gcagttatct ctaaaggtaa agaagctatt actaaatggt ttaaaaaagt
     8461 tgaacctaag gttgttagtc aaacagctca gtatgatacg gttcgtcagt tgactgctga
     8521 agagaaagaa aaactttctg tttctagtgt tgatgattta gttgatcaag gattaatgtc
     8581 agacagagct gtaggaaata atacctataa tccagctgat tttgaaacaa gttatattgc
     8641 gatagattat atgactggta tttatggtgg aggaaagaat agtgtaggtt caccaggtgc
     8701 cttgatgttt aaacataata ctttccgtat gtggggctac tatggttttg aagaaggtgt
     8761 tctaggatat gcttctaata aatttaagca agcatctaga gatgaaggtc atgctggact
     8821 tagtgataac tttattattt ctaagatttc caaaggggaa tttttaacta tggaagcatt
     8881 taaaaaggga tattttaaga aagtagtaga agagttaaaa actaaaggta ttcgtcctgt
     8941 tactatcaat caaaaaacat atagcacctt tgaagaattg caagaaggat ttaagcaggc
     9001 tgttgaaaga gatttgaaga aaaatcagtt agatgagagg gaaacaagaa acttcaaatt
     9061 ccaagttttc agacaacttc ttcaacaaac agatagcttt aaaacttcta tctttagata
     9121 atcgaaatct ctcatctgct ttgcggatga gggttttctt attttatgct atacttaaag
     9181 tatgcataga aaaacagtga ttgattttag gactttgggg gagagatata cctttaccca
     9241 gcctattaaa gagttgaaaa cgagaaatgt agaagaagtg gcagatttgc tggcacaagt
     9301 ggaaagctac caagagcaag gttattatgt ggtggggtat gtcagctacg aggctgcacc
     9361 tgcttttgag gagaaattaa cagttcacaa ggttcctcta ctgggcgagt acttgcttta
     9421 ctttactgtt cacgataggg tagagacctc ccctattcct ctgacttatg aggatattga
     9481 tttgccctca aattggcagg aagtgacgtc tgcagcagac tatgaaaagg ccattgccca
     9541 gatacaccat cacttgaggc agggagacac ctatcaggtc aactacaccg tccaactcaa
     9601 gcaaaagtta agtgccaatc cttttgccat ctacaatcgt atggtggtag agcaggaggc
     9661 gggctacaat gcctacgtgg aacatgacga gatggcagtg atttccatga gcccagagct
     9721 cttttttgag caaaatgatc gcgagttgac aacacgacca atgaagggga cgactcagcg
     9781 tggggtaact gaccaagaag atcttgaaca ggccagttgg ttggaacagg atcccaaaaa
     9841 tcgctctgaa aatatgatga ttgtggacct cttgcgcaat gatatgaacc gtatttctga
     9901 agttgggagc gagcacgtgg agcgtctgtg tcaggtagag cagtattcaa ctgtttggca
     9961 gatgacttcg accatcaaga gtcagttgcg agaggatgtg gaccttgttg aaatcttccg
    10021 ctcactcttt ccttgtggtt ccataacggg tgcaccgaaa attgcgacaa tggagattat
    10081 caaggacttg gagcctcaac cgcgtggagt ctactgtgga acgattggtc tcttgcttcc
    10141 aaatggacga cggattttta atgtggccat tcgtaccatt caacttcaca aaggtcaagc
    10201 catttatgga gttggcggag ggattacttg ggatagcaca tgggaatctg aataccgaga
    10261 ggttcatcaa aaggcagcag ttctttatcg taaacaagcc cgcttccaac tgattacgac
    10321 aggggaaatc agccagaaga acctgctgtt tgaagatcaa catctggaaa gactgagaaa
    10381 agccagtcgt tattttgcct ttccttttga tgcagaagac ttgggacaca agattgagga
    10441 agagtgtcag gattgtgaag ctaatcgaga ttaccgcttg cgaatcagcc ttagcaaatc
    10501 tggagagata gaagtcaatc gtcaagtatt aacccctctc agtacaagct tttgtcaggc
    10561 ccaagtctgt cttcaggaag ctgctttgaa tcaatccttt acctacttta aaaccactca
    10621 ccgatcgcat ttgagcctag gagaacaaga gaagatttac cacaataagt caggagaact
    10681 gcttgaaacc tctataggaa atttggttct gaaaatcgct ggaaaactct acacaccgcc
    10741 tatccgactt ggaatcttgc caggaattta ccgtcagcat ttgctagaaa caggacaggt
    10801 agaagagaaa gtcttgacct tggcagattt aacccaagca gaagctattt acggctgtaa
    10861 tgcagtgaga ggcttgtatg aactaagcct tgaggagaac tagatgaaat tgatattttt
    10921 gcatgggtta gggcagtcag cagagtcttg gaaagaagtt cggaatctac tgacagatta
    10981 tccttctgag gctatcgagt tatttccttc tggagttagt aactatcaac aagctaaaga
    11041 gcgagtttat cagcacctag ctcaagagac agaacctttt gttttgattg gattgtcctt
    11101 aggtgctgcc ctgacactag aactttccag ttacgattta ccaaatcttc gagatttgat
    11161 tctgtcagga tgcccgctta aattagcagg gaatatccta ttttatcttc agttgctgat
    11221 ttttaaacta cttcccaaaa gagtatttga aaaacaggga gcagacaaga ctcttatggt
    11281 cggagtttct gaggagttga agacacttga tttaacggat atagcaggaa cttgccctta
    11341 tccaacctta ctaatttgtg gcagcaaaga taaaccgaat cttagttcta tgaaagctct
    11401 ccatagactg ttaacagatt cgcagtttca gatcattcct tatggccctc atgtcttgaa
    11461 taaggcaaaa ccaaaggagt ttgtagaaaa gaccagaagt ttccttgaat tgctgaaata
    11521 agtttgataa aataatattg aaatcgatat cataattatg ggagaaagaa atgaataaac
    11581 gtctattttt aaaaatgagt ctggtgacgt tgccaatttt agccttgttt tcacaaccag
    11641 ttttggcgga agaaaacatc catttttcga gctgtaagga agcttgggcg aatggctatt
    11701 cggatattca cgagggagaa cctggttatt ctgccaagtt agaccgtgat catgatggtg
    11761 tggcttgcga attgaaaaat gctcctaagg gtgcttttaa agcaaaacag tcaacggcta
    11821 ttcaaatcaa cacaagttca gcaacaacaa gtggttgggt taagcaggac ggcgcttggt
    11881 actactttga tggaaatgga aatctagtga aaaatgcatg gcagggaagc tattacctga
    11941 aagctgatgg taaaatggca cagagtgaat ggatttatga ctcttcttat caagcttggt
    12001 attatttgaa atcagatggt tcttatgcaa aaaatgcatg gcaaggagct tattacctta
    12061 aatcaaacgg taaaatggca caaggtgagt gggtttatga ttcttcttac caagcatggt
    12121 attacttgaa atcagatggt tcatatgctc gcaatgcatg gcaaggaaac tactatttga
    12181 aatcagatgg taaaatggct aaaggtgaat gggtttatga tgccacctat caagcttggt
    12241 attatttgac atcagatggt tcttatgctt acagtacatg gcaaggaaat tactatctaa
    12301 aatcggatgg taaaatggct gtcaatgaat gggttgatgg tggacgttat tatgttggcg
    12361 ctgacggagt ttggaaggaa ggtcaagcaa gtacagcttc ttctagtaat gatagcaata
    12421 gtgaatattc tgctgcttta ggaaaggcaa aaagttataa ttcgttattc cacatgtcaa
    12481 aaaaacgtat gtatagacaa ttaacttctg attttgataa attttcaaat gatgcagctc
    12541 aatatgccat tgatcattta gatgattaac agatactggt aggcgaaaaa attccttata
    12601 attcatttac gcaaaccttt gcataagtga atggattttg atatactagt actgtaagca
    12661 ttttcaatta ctacacaatg aaaaaggaga atatgatgag tcaaaagatt attgggattg
    12721 accttggtgg aacttctatc aaatttgcaa tcttaacaac agcaggagaa atccaaggaa
    12781 aatggtcaat caagaccaac attttggatg agggaagtca tatcgttgat gatatgattg
    12841 agtctattca acatcgtttg gacttgcttg gattggcagc agcggacttc caaggcattg
    12901 gaatgggatc accaggtgtg gttgaccgtg acaaagggac tgttatcggt gcctacaact
    12961 tgaactggaa aacccttcaa ccaatcaaac aaaagattga aaaagctttg ggcattccat
    13021 ttttcatcga taatgatgcc aacgtagcag ctcttggtga gcgctggatg ggtgctggag
    13081 ataaccaacc agacgttgtc tttatgacat tcggtactgg tgttggtggt ggtattgtcg
    13141 cagaaggcaa attgcttcat ggtgttgctg gtgcagcagg tgaacttggt catatcactg
    13201 ttgactttga ccaaccaatc tcatgtactt gtggtaaaaa aggctgcctt gagacagttg
    13261 cttcagcaac agggattgtc aacttgactc gtcgctatgc cgatgaatac gaaggcgatg
    13321 cagccttgaa acgcttgatt gataacggag aagaagtaac tgctaagact gtctttgatc
    13381 tcgcaaaaga aggagacgac cttgctttga ttgtttaccg taacttctca cgttacttgg
    13441 gaatcgcttg tgctaacatt ggttcaatcc taaacccatc aacaatcgtc atcggtggtg
    13501 gtgtgtcagc tgcgggagaa ttccttctac aaggtgttca aaaagtttac gatgaaaata
    13561 gtttcccaca agtacgcaca tctactaaat tagctcttgc aactctagga aatgacgctg
    13621 gagttatcgg agcagcatca cttgtattgc aataagataa tgagagagga aaatgctaac
    13681 ctagagttag taatgttcct cttttatttt ttatgctata ctagttagga caatgaatga
    13741 ggtgaaacga aatgacaaaa gcagatacga tttttaaaga gaatattgaa tgcattctaa
    13801 aggaaggtgt tttctcagag caggctcgtc ctaagtacaa ggatgggact gttgctaatt
    13861 ccaagtatgt aactggtgcc ttttccgagt acgacttatc taaaggagaa tttcctatca
    13921 caaccttgcg tcccattgca atcaaatccg ccatcaaaga agttctctgg atttaccaag
    13981 accagtcaaa tagcttagaa gtgcttaatg acaagtacaa tgttcactac tggaatgact
    14041 gggaagttgg agacacggga accattggtg agcgctatgg tgccgttgtt aagaaacacg
    14101 acattatcaa taagcttctc aaacagttgg aaaccaatcc ttggaaccgc cgcaatatta
    14161 tttcgctctg ggattaccaa gctttcgaag aaacagatgg gctgctcccg tgcgcctttc
    14221 agaccatgtt tgatgtccgg cgtgttgatg gggaaatcta tctggatgcg accttgaccc
    14281 agcgctccaa tgatatgctg gtggcccacc acatcaacgc tatgcagtat gtggctttac
    14341 agatgatgat tgccaaacat tttggttgga aggttgggaa gttcttctat ttcatcaaca
    14401 acctccatat ctatgataat caatttgaac aagctcagga attgctccgt cgggagccgt
    14461 caaactgcca accacgcttg gttttaaatg ttcctgatgg gactaatttc tttgatatca
    14521 aagcagaaga ttttgagttg gtggattatg accctgttaa gccacagttg aagtttgacc
    14581 tagctattta aaagaataga aaaaagaagt tgagaataat cccaacttct tttgtttctt
    14641 aacgtgatac gcggcgacga gctgcttttt tacgattttc ttcgatgaaa gctgcttttt
    14701 gctcttctgg ttcgattact ttctttttaa atgcgtatac tgcacctgca acggcagcga
    14761 cagttcctgc gacacctgtt acaagacctt tagcgaatcc tttagccatg agtcttcctc
    14821 ctttatattc tcaatcagcc agcctcctca agaggtcaca tttttctgac tgaccttttt
    14881 gtgttataat aatagtaacg aaaaaatggg aatttttcaa ggaaaaaaga tgaaaacaaa
    14941 aataattgtg attgttggac cgactgctgt tggaaagacg gctctagcta ttgaagttgc
    15001 aaagcgcttt aatggcgaag tggttagtgg agatagccag caagtctatc gaggacttga
    15061 tattgggacg gccaaggcta gtccagaaga gcaggcagct gttcctcatc atttaatcga
    15121 tgttagagag ataaccgagt cttactcggc ttttgatttt gtttcagaag ctaagatgac
    15181 tattgaggat attcagagcc gtggcaagct agccattatc gccggtggga ctggacttta
    15241 tatccagagc ttgctagaag gttaccacct aggtggggag actcctcatg aggagatttt
    15301 agcttatcga gctagtttgg agccatattc agatgaggaa ttagcccatt tggtggagca
    15361 agcaggcctt gagattcccc agtttaatcg tcgtcgtgct atgcgtgcct tagaaattgc
    15421 ccattttggt caggatttgg aaaatcaaga gatcttgtat gaaccgctga ttatctgctt
    15481 ggatgatgaa cgtagtcaac tttatgagcg tatcaaccac cgagtggatt tgatgtttga
    15541 ggctgggctt ttggatgagg ccaagtggct gtttgaccat tcccctaatg tacaggctgc
    15601 taaaggaatt ggctataagg aactctttcc ttatttccgt ggagagcaga cctttgagga
    15661 agctcgtgag agtcttaaac aggcgacccg tcgttttgcc aagcgtcagc tgacctggtt
    15721 ccgtaatcgc atgcaggtca ccttttatca gattggagaa tctggtgtac aagaccgcat
    15781 tttaagccag atagaggagt ttttagatga ttgaaacgga gaaaaaagag gagcgagtcc
    15841 tgctgattgg tgtggaattg cagggtatgg acagttttga cctctccatg gaagaattgg
    15901 ctagtttagc gaaaacggca ggggcagtcg ttgtagatag ctacagacaa aaacgtgaaa
    15961 aatatgattc caagaccttc gtcggctctg gtaagttgga agagattgcg cttatggtgg
    16021 atgcagaaga aatcactact gtcatcgtca acaaccgtct gaccccaagg cagaatgtca
    16081 atctagagga agttctgggt gttaaggtca ttgaccgtat gcagttgatt ttggatatct
    16141 ttgccatgcg ggctcgaagc catgaaggga agctccaagt ccacctagcc caactcaaat
    16201 acctcttgcc tcgcttggtt ggtcagggga ttatgctcag ccgtcaggca gggggaattg
    16261 gttcccgtgg tcctggtgaa agccagctgg agctgaaccg tcgtagcgtt cgcaatcaaa
    16321 tcacggatat tgagcgccag ctcaaggtgg ttgagaaaaa tcgtgcgact gtcagagaaa
    16381 aacgtttgga gtctagcact tttaagattg gtttgattgg ttatactaat gctgggaaat
    16441 caactatcat gaacatcttg accagtaaga cccagtatga agcagatgag ctctttgcga
    16501 ctctggatgc gacaaccaag agtattcatc tgggaggcaa tctccaagta actttgacag
    16561 ataccgttgg ctttatccaa gatttgccga cagagttggt gtccagtttc aagtcaacct
    16621 tggaagaaag caagcatgtg gaccttctgg ttcatgttat cgatgctagc aatccttacc
    16681 acgaggagca tgaaaaaacg gttctctcca tcatgaaaga cctggacatg gaagatattc
    16741 ctaacttgac gctttataat aaagcggatt tggtggagga tttcacgcct acccaaacgc
    16801 catataccct catttctgcc aagtctgagg acagtcgtga aaacttgcaa gcattattgc
    16861 tagataagat taaggaaatt tttgaagcat ttaccctgcg agtgcctttt tcaaagtcct
    16921 acaagattca tgatttagag agtgttgcaa ttctggaaga acgtgattat caggaagacg
    16981 gcgaagtgat tacaggctac atttccgaga aaaataaatg gaggttagaa gaattttatg
    17041 actgatatta aaactttggc tctaaagtat ggaggttata caagtctgga caaggtctat
    17101 ctggatcagc ttctagctgg taaaacagat caggagcagt taacacttat tacacctccg
    17161 ccaagtgttg ttaatgccta ctttgcagaa ctctatcaga aaaagagtcc tcaggctgcg
    17221 acggattatt ttgcagaact cagtcaggaa ctgaatcttt acaatactga gccaagtttc
    17281 actctagaaa ataagccttt tattcggctt aatctgtctg gtaaatcctt tggtttttgt
    17341 tatgagagtg acggccttgg tcggattttc tttgaaaatg aggagaaaat ctcggatgac
    17401 ttgctctttg aaattgcgca aattttcccc catcaattag tctttgaaga gtctggtaag
    17461 atttacatga agcttgtcga ggacgaggaa gttatcagcc tagaaagtct cacagctttg
    17521 actgatttgg aaagattggc tgatggtcga aaacgtctca aaggctacag ccaagaggat
    17581 ttattgcaag aagctgctgc tttttctggc aaacgctatt tccgatcgga aaaccgcaca
    17641 gccatgttat atattgatta attagaaagt atcgaatgga tattcaattt ttaggaacgg
    17701 gggctggtca gccctctaaa gcccgcaacg tttcaagtct cgccctgaaa cttttggatg
    17761 agattaacga agtttggctc tttgactgtg gagaaggtac gcaaaatcgc attctggaaa
    17821 ccacaattcg accacgtaag gtcagcaaaa tctttattac ccatctgcat ggagaccaca
    17881 tttttggttt gccaggtttc ctttctagcc gtgcctttca ggccaatgaa gagcagacag
    17941 atttggaaat ctacggacct caaggaatca agtcatttgt cttaaccagc cttcgtgtgt
    18001 caggttctcg tctgccctac cgcattcatt tccatgagtt tgaccaagat tctctgggta
    18061 aaattcttga aaccgataaa ttcactgtgt atgcagagga gctggaccac actattttct
    18121 gtgttggcta tcgtgtcatg caaaaggatc tagaagggac gctggatgct gaaaaactca
    18181 aggctgctgg tgttccgttc ggcccgcttt ttggtaaaat caaaaacggc caggatcttg
    18241 ttttggaaga cggaactgaa atcaaggcag cagactatat ctcagcgcca cgtccaggta
    18301 agattatcac tattttagga gacactcgaa aaacgggtgc cagtgtgcgt ctggctgtca
    18361 atgcagatgt cctagttcat gagtccactt atggcaaggg tgatgaaaaa attgctcgta
    18421 accatggtca ctcaactaat atgcaagctg cacaagtagc ggtagaagca ggtgccaaac
    18481 gcctcctact caaccatatc agtgcccgtt tcctctcaaa agatattagc aaactcaaga
    18541 aagacgctgc cacaattttt gaaaatgtcc atgtggtcaa agacttggaa gaagtggaaa
    18601 tctagcagtc acagaaagga taagtatgcc tactattctc attaccggag ctagcggtgg
    18661 tctagctcaa gaaatggtca aactcctgcc caatgaccaa ctcatcttgc ttggtagaaa
    18721 taaggaaaaa ttagcccaac tctacggaaa ttattcccat gcagaattga ttgaaattga
    18781 tattaccgac gattcagccc tagaagctct ggtaactgat ctttatctcc gctatggcaa
    18841 gattgatgtc ttgattaaca acgctggtta cgggattttt gagggatttg accagattgc
    18901 tgataaagat attcaccaga tgtttgaggt caataccttt gccctgatga atctgtctcg
    18961 tcaccttgcg gctcgtatga aggaaagcag caaagggcat atcatcaaca tcgtcagcat
    19021 ggcaggtcta atagctactg gcaagtctag tctttactca gcgaccaagt ttgcggctat
    19081 tggtttttca aatgctctgc gactcgaact tatgccctat ggagtctatg tgacaacagt
    19141 caatccagga ccaatccgta caggattttt cgaccaagcc gacccagatg gaacttatct
    19201 taaatcggtt gatcgcttcc tgctagaacc agatgcagtg gctaaaaaga ttgtcaagat
    19261 tataggaaaa aacaaacgag aactcaatct cccgattttg ttgaacctag ctcataagtt
    19321 ttataccctc tttcctaagc tagctgataa gttggcaggg gaaactttta attataagta
    19381 aaaagaacca atgtgcaggt tgttgctagc ctacatattg gttcttatca tttctcaact
    19441 atcaaactga acttcttcta ggagatagtc tataaagcgt tcgcccatct tagataggct
    19501 ggttttctca tgctggatat agaccagctc aatcgggtca tcaatatcca gtgggataga
    19561 aacgatattg tctccgttta ggttgctgtt caaaatccct gtcgcaatgg tataaccatc
    19621 caaaccaatc aagagattaa agagggtggc acggtcactg accacaatgg atttcttgtg
    19681 gtgttcttga gaaagaatct cttctgaaaa gtagaaggag ttgtgcgtcc cttggtcata
    19741 gctgaggtaa gggaaattct ccaaatcaga cagtttcacc ttgtctttct ttgccagagg
    19801 gttggtcttg ctgacaaaga tatgcggttg cgctgtgaag agatggtggg ctagcaggtg
    19861 attgtcatcc agcatcttgg ttaaaacatc acggttgtaa ctgtttaaga agaggacccc
    19921 gacctcactg cggaagttct tgacgtcgtc gataatctcc caagtccgag tttcacgaag
    19981 gaagagttcg tatttctcca tatcgctttt cttgagcaaa gagacaaagg cattgaccac
    20041 aaaggcatag tgttgagacg aaacgctaaa gagttcgcgg tgggcgacag gatttttata
    20101 gcgttcctcc agaagctggg tctgctcgac aacctgacgg gcataagaga gaaactccat
    20161 cccatcacgg gtcaaggtga ttcccttggg attgcggata aagatctcaa tgcccatttc
    20221 attttccaaa tctcgcactg cattggagag acttggctga gtgataaaga gttgcttggc
    20281 tgcctcattc atggagccag tttcgacgat tttgataata taatgtaatt gttgaattct
    20341 catgttttta ttgtaccata cttgccttag aatcgctaaa gaagatagga aaataaggag
    20401 cattgtgtga gtctcttctt gaaaaaaaca caaaattttg ctagaatgag tcttatgaaa
    20461 acattctatg atgtgcagca attcctcaaa cgatttggta ttattgttta catgggaaaa
    20521 cgcttatatg atattgaact gatgaagttg gaactatctc ggatttacga tgcagggttg
    20581 atggataaat tagactatct agaggcagaa gcagttcttc gcagagagca caaggtagaa
    20641 ttggattata ttgagaaaaa tggagaaaag aactaatggt tacttggatt ttgtgggcac
    20701 ttatactagc aatgttggcg tggatgggct ttaactatct tcgtattcgc cgtgcggcta
    20761 aaattgtgga caatgaggag tttgaagcct tgattcgtac gggtcaattg attgatttgc
    20821 gcgacccagc agaattccac agaaaacata tccttggtgc acgcaatatt ccttcaagtc
    20881 agttgaaaac tagtcttgca gcccttcgta aagataaacc tgtccttctc tacgaaaacc
    20941 aacgtgcgca acgagttaca aatgcagctc tttacttgaa aaaacaaggt ttttctgaga
    21001 tttatatcct ttcttatggc ttggattctt ggaaagggaa agtgaagact agctaacctt
    21061 atttccaaat tagtcgaatg ataggatgaa gctattgttt tatagtataa ttaatttgta
    21121 taaaatttaa ggagttctta gaacataaaa gaaaagaaga aaaatccact ttttgtgggt
    21181 atcttgtcga ttattcttgg tttgttattt ccaattgtag gcctgatttt gggtatcata
    21241 ggattggtct tggctatttc ataccaaaaa gagtcacaat tagactataa aatagaaaag
    21301 attcttaata tcttaggaat tgtgatttct gtagttaact ggattgtagc aatcgcctta
    21361 atttttcggt aaataaaaga aaaaagcttt agttttaaag ctttttttgt tttatcgact
    21421 catctctaaa tagtttttaa tgatttgtaa ctctttttgg ttcaaagggc ggtagttact
    21481 ttctgctaaa tctgggttca atgtgaagtc cccaaattgg attctcttga ggctagtcac
    21541 cttaacacca accgagagga acattttctt gatttgatga aattttcctt ctgaaatggt
    21601 gatagaggct tgactgaagg aaggacttgc tgatagaatc tctagtcttg caggtttaca
    21661 gatagtgcca tctaaaaaga caattccttt ttgaaaggtt tggatatggt caggtgttag
    21721 aagtccatta acctggactt ggtaagtctt atcgacatga tattggggat ggaggagttg
    21781 gaagcccaag ggaccgttat cggtcaagag aaggagtcct gttgtatctc ggtccagtcg
    21841 gccgacggca tagagcttgt cagactggat gtcagatgga agcaggtcca tgacggtcgg
    21901 aagttccttg tctttgttgg ctgtaacgac accagcaggt ttatgaagca taagataggt
    21961 gtgttcatag ccttgaatga ttcgatcctg aaaaaggagt tcttgtagtc ctgtatcgat
    22021 attttgagct agggagcggg ctgggcaacc atcgactaga atttcccctc tgaggagtgc
    22081 ttgcttcatg gcctttcggc tgattttttc ttgggctaat aaattatcta aacgcatact
    22141 gtgcctatct tatcataagt cgctcgcttt gaaaaggctt gacgtgaaaa gaaaagcaga
    22201 gtgaaaacat ttacacttgc ttgagttatg ttatttactt gaaattatgg tataatcgtt
    22261 cagttagaaa ataaattttg aatattatag aggaaatcat gacaaaatta agagaagata
    22321 tccgtaacat tgcgattatc gcccacgttg accacggtaa aacaaccctg gttgacgaat
    22381 tattgaaaca atcagaaacg cttgatgcac gtactgaatt ggcagagcgt gctatggact
    22441 caaacgatat cgaaaaagag cgtgggatta ccatccttgc taaaaatact gccgttgctt
    22501 acaacggaac tcgtatcaac attatggaca caccaggaca cgcggacttt ggtggagaag
    22561 ttgagcgtat catgaaaatg gttgacggtg ttgtcttggt cgtagatgcc tatgaaggaa
    22621 ccatgccaca aactcgtttc gtattgaaaa aagccttgga acaagacctt gtcccaatcg
    22681 tggttgttaa caaaatcgat aagccatcag ctcgtccagc agaagtagtg gatgaagtct
    22741 tggaactttt catcgagctt ggtgcagatg acgaccagct tgatttccca gtggtttatg
    22801 cttcagcgat caacggaact tcttcattgt cagatgatcc agctgaccaa gaagcgacta
    22861 tggcaccaat ctttgacacg attatcgacc atatcccagc tccagtagat aactcagatg
    22921 agcctttgca gttccaagtg tcacttttgg actacaatga cttcgttgga cgtatcggta
    22981 tcggtcgtgt cttccgtggt acagttaagg ttggggacca agttaccctt tctaaacttg
    23041 acggtacaac taaaaacttc cgtgttacaa aactcttcgg tttctttggt ttggaacgtc
    23101 gtgaaatcca agaagccaaa gcgggtgact tgattgccgt ttcaggtatg gaagacatct
    23161 ttgtcggtga aaccatcact ccgacagatg cagtagaagc tcttccaatc ctacacatcg
    23221 atgagccaac tcttcaaatg actttcttgg tcaacaactc accatttgct ggtaaagaag
    23281 gtaaatgggt aacttctcgt aaggtggaag aacgcttgca ggcagaattg caaacagacg
    23341 tttcccttcg tgttgaccca actgattcac cagataaatg gactgtttca ggacgtggag
    23401 aattgcactt gtcaatcctt atcgaaacaa tgcgtcgtga gggctatgaa cttcaagtat
    23461 ctcgtccaga agttatcgta aaagaaatcg acggtgttaa atgtgaacca tttgaacgtg
    23521 tacaaatcga cactccagaa gaataccaag ggtctgttat ccaaagcctt tctgaacgta
    23581 aaggtgaaat gttggatatg atttcaactg gtaatggtca aactcgtttg gtcttccttg
    23641 ttccagcgcg tggtttgatt ggatactcaa ctgagttctt gtcaatgact cgtggttacg
    23701 gtatcatgaa ccataccttc gaccaatact tgccattgat tccaggggaa attggtggac
    23761 gtcaccgtgg tgcccttgtt tctatcgatg ctggtaaggc tacaacttac tcaatcatgt
    23821 ctatcgaaga acgtggtacg atctttgtca acccaggtac tgaggtttat gaaggaatga
    23881 tcatcggtga aaactctcgt gaaaatgact tgacagttaa catcacgaag gcaaaacaaa
    23941 tgaccaacgt tcgttcagct actaaggacc aaacagctgt tatcaagacg cctcgtatct
    24001 tgacacttga agagtctctt gagttcttga acgacgatga gtacatggaa gtaacgcctg
    24061 agtctatccg tttgcgtaaa caaatcctta acaaagcaga gcgtgagaaa gctaacaaga
    24121 agaaaaaatc agctgaataa gagctagaaa gagagaaaga tggtctattt agtcctagga
    24181 attttactgc tcctactcta tgtatttgcg acaccagaaa gcattaaagg gactgtcaat
    24241 atcgtcgcta tggtatgtat tttagtggca ctcttgattt tattggttct atcttttctg
    24301 aaaatttttc aattaccaac agaaatattc ctagcaatag ccatgttgat cctagcttac
    24361 tttagtgtta gagacatcac actcatgcca gtcaaaaaaa gtaaaagaag ataaaaaaga
    24421 gagtttcggc tctctttttg ctaggaattt tacaatagtt tgaattgctt tttagttaac
    24481 accatctctt ttacttgtat agtatgaatg ggaaaaactt gaataaaatt cgttaatggc
    24541 atctatttta tatttggtta gtactggttg catattattt tgaaataaaa ctactatata
    24601 atattattca cagaggtaat atagtaaaat atctaaaaaa ttcgattttt tccttgacaa
    24661 caaataataa aaaagttatt cttatcacat aagaaagcgg tttcaataaa agatagagga
    24721 ggatttattt tgttgcattg ttgctcaagg tgtgcttttt ttgaaagaaa aaataaaatg
    24781 aaaacgaaaa aacatagatt acttgctcta gctcttattt caaattttac attattggga
    24841 gctgcatcag ctgctgtaca atatccagat ggaggagtat ggacatatgg agaaggttca
    24901 ggaggtggtt gggctttttc aaattactat catggtaaaa aatatcatta ttcttctctt
    24961 gtaagtagat ggaatagtca ttcagataaa ggagaagctt ctgctggaaa aacctcctat
    25021 gcatggattt ggactaaatg gggagaacaa gtagcatttt actgtgatta tgactaatcg
    25081 ttcattgatt taaatcgttc cccttgtaag aaattacagg gggaattttg tttacaagga
    25141 gtctactatg aagaaactat tcatattatt atcaactttt tttctcagct ttttccttgc
    25201 ttggattatt gtcttacgtg cgccacaata tttatatgca agctatgatt ccgtttcttt
    25261 acttcgtgtc aaaaaagata ctcaggaacc gacgcgtgag gtatttgaac aggaattgga
    25321 gaattttgca aactcagaac agagtttaat agctagaaga attgtagagc cgagtaagga
    25381 tgggacgact cactttactt atgcaactta tggtcaggga actttaccaa aagaattcca
    25441 agaagctagc caagaaagtc gtgaacgtag tgatccgcta aatagttatc tccttttgtc
    25501 aggctccttg acgaaagaaa agcttgccga taaattagga gatttgggtt ataaagcaag
    25561 tgctgaccga aagataccgc cctattttct tgcttttcga atattactaa atccccttat
    25621 tttaattagt ttagcaatat ttggcttatc tttctttgct ttagtgatta tcactcggat
    25681 taaggaaatg agagcagcag gtataaaact cttttctggt cagactctct tatccatcat
    25741 ggggcattct ttatctactg atatcaaatg gctccttcta tcagccctcc tttccttcct
    25801 aggtggggga gtcgttcttt ttagtcaagg tttgttttat cctatcttgt tagccaccta
    25861 tggttttggg attagtttct atctgttgtt tttattggcg atttcaattt tactaatgct
    25921 cctttaccta atgagtttga gttacaaagc attagttccc gttattaagg gaagattacc
    25981 ccttaaacgc ttgatggctt taaccctatt gtgtcagtta gtagctgttt ttacagtagg
    26041 ctacgctgtt aagacaggtt tgacgtctta ccaacgattg aaagaacttg aaatttcaaa
    26101 acaagcatgg caggatagag cagactatta ccagatttcc tttggcttag gtgatagagg
    26161 aaaagataca gaaaatcaga gcaagtggta tgcctttgcc aaggaagcaa tcgaagaaga
    26221 acaagctctt tatgtaaagg ataatctgct ccattttgcc aatccacaag gaaaaaatga
    26281 agagggagag acactggata cctatagtcc agatgctaat acgctctatg ttagtcccag
    26341 ttatttggac aaggaaaagg tcgtggtaga tgctgagacc aaacagaagt tagcccatct
    26401 ccaaaaaggt gagtttatcc tcttgctccc agaacatttg cgctctcgag aagcagaact
    26461 taagaaagtt tttgaagaaa gattgagtta ttatggaaaa tctggtgagg aggcaagtgc
    26521 tcctttggat tatgagatga aagcgcacgt tagttatctt tcaatgggag aaaagcggtt
    26581 tgtttataat aacggtgaga atcccgtatc tactcagtat ttgactgatc cgattttagt
    26641 ggtattcacg ccgacttcta caggtgatag ttttatatcc ttatctagtt ggtctatcaa
    26701 tgctggaaaa caactcttta tcaaaggata tgagagtggg attaaactct tgaaaaatgc
    26761 aggaatttat gagcaagtat cctatcttaa agaaggaaga agtgtttatc taactcgtta
    26821 taatgaagtt caaactgaaa cagcaacttt aatcctagga gctattgttg gaatagccag
    26881 ttccttgtta ctcttttatt ctgtcaatct tctatatttc gagcaattcc gccgagatat
    26941 cttgattaaa cgaatttcag gtttacgatt ttttgaaaca catgctcagt atatggttag
    27001 ccaatttgcc agttttgtat ttggtgctag tctctttatt ttaagcagtc gagacttggt
    27061 gattggcttg ctcactttat tggtctttct agctagtgca gttttgacgc tttaccgtca
    27121 agcgcagaaa gaatctcgtg tttctatgac aattatgaaa ggaaaatagg atgattgaac
    27181 taaagaatat atctaaaaaa tttggaagcc gtcagctatt ttcagatacg aatcttcatt
    27241 ttgaaggtgg gaaaatttat gccttaatcg gtacaagtgg ctgtggtaag acaacactct
    27301 tgaatatgat tggacgatta gagccatatg acaaagggca aatcatctat gatggcactt
    27361 ctcttaagga catcaagcct tctgttttct ttagagatta cttgggatac ttatttcaag
    27421 attttggctt aattgaaagc caaaccgtca aagagaatct caatctgggt ttagttggta
    27481 aaaagttgaa ggaaaaagag aaaatctctt tgatgaaaca agctctaaac cgtgtaaacc
    27541 tctcttattt ggatttgaag caacctatat ttgagttatc aggaggagaa gcacaacgtg
    27601 ttgcactagc gaagataatt ttaaaggatc cacctttgat cctcgcagat gaaccaaccg
    27661 cttcactaga ctccaaaaac tctgaggaat tactttccat cctagaatct ttaaaaaatc
    27721 cgaatcggac cattattatt gcgacccaca atcctctgat ttgggagcaa gtggatcagg
    27781 tcattcgagt taccgattta tcacatagat gatatggtaa gattcagtta gaagaaagag
    27841 tcacaaacac actttgtggc ttttttattt ccataaaaat ggtaaaatag taggagtaga
    27901 aatggagttc gagacatgaa agtaatagat caatttaaaa ataagaaagt tcttgtttta
    27961 ggtttggcca agtctggtga atctgcggct cgtttgttgg acaagttagg tgccattgtg
    28021 acagtaaatg atgggaaacc attcgaggac aatccagctg cgcaatgttt gctggaagaa
    28081 gggatcaagg tcattacagg tggccatcct ttggaactct tggatgaaga gttcgccctc
    28141 atggtaaaaa atccaggtat cccctacagc aatcccatga ttgaaaaggc tttggccaag
    28201 ggaattccag tcttgactga ggtggaattg gcttatttga tttcagaagc accgattatt
    28261 ggtatcacag gatcgaacgg taagacaacc acaacgacta tgattgggga agttttgact
    28321 gctgctggcc aacatggtct tttatcaggg aatatcggct atcctgccag tcaggttgct
    28381 caaatagcga cagacaagaa cacgcttgtt atggaacttt cttctttcca actcatgggt
    28441 gttcaagaat tccatcctga gattgcggtt attactaacc ttatgccaac tcatatcgat
    28501 tatcatggat tatttgagga atatgtagca gccaagtgga atatccagaa caagatgaca
    28561 gcagctgatt tccttgtctt gaactttaat caagacttgg caaaagactt ggcttccaag
    28621 acagaagcca ctgttgtacc attttcaaca cttgaaaagg ttgatggagc ttatctggaa
    28681 gatggtcaac tctacttccg tggtgaagta gtcatggcag cgaatgaaat cggtgttcca
    28741 ggtagccaca atgtggaaaa tgcccttgcg actattgctg tagccaagct tcgtgatgtg
    28801 gacaatcaaa ccatcaagga aactctttca gccttcggtg gtgtcaaaca ccgtctccag
    28861 tttgtggatg acatcaaggg tgttaaattc tataacgaca gtaaatcaac taatatcttg
    28921 gctactcaaa aagccttatc aggatttgac aacagcaagg tcgtcttgat tgcaggtggt
    28981 ttggaccgtg gcaatgagtt tgacgaattg gtgccagaca ttactggact caagaagatg
    29041 gtcatcctgg gtcaatctgc agaacgtgtc aaacgggcag cagacaaggc tggtgtcgct
    29101 tatgtggagg cgacagatat tgcagatgcg acccgcaagg cctatgagct tgcgactcaa
    29161 ggagatgtgg ttcttcttag tcctgccaat gccagctggg atatgtatgc taactttgaa
    29221 gtacgtggcg acctctttat cgacacagta gcggagttaa aagaataata tgaaaaaaat
    29281 tgtctttaca ggtgggggga cggttggaca cgttaccctc aatcttttgt taatgcccaa
    29341 gttcatcgaa gatggttggg aagtccacta tatcggggac aagcgtggta ttgaacacca
    29401 agaaatcctt aagtcaggtt tggatgtcac cttccattct attgcgactg gaaaattgcg
    29461 tcgctatttc tcttggcaaa atatgctgga cgtcttcaaa gttggctggg gaatcgtcca
    29521 atcgctcttt atcatgttgc gacttcgtcc acagaccctt ttttcaaagg ggggctttgt
    29581 ctcagtaccg cctgttatcg ctgcgcgtgt gtcaggagtg cctgtcttta ttcacgaatc
    29641 tgacctgtct atgggcttgg ccaataaaat cgcctataag tttgcgacta agatgtattc
    29701 aacctttgag caagcttcga gtttgtctaa ggttgagcat gtgggagcag tgaccaaggt
    29761 ttcagatcaa aaaaatccag aaccagatga attggtggat attcaaagcc actttaatca
    29821 taaattgccg actgtattgt ttgttggtgg ttctgcaggt gctcgtgtct ttaaccaatt
    29881 ggtgacagac cataagaaag aactaacaga gcgctacaat attatcaatc taactggaga
    29941 ttctagcctg aatgagttga gccaaaatct ttttcgtgtt gactatgtga ccgatctcta
    30001 tcaacccttg atggaattgg ctgatattgt tgtgacacgt ggtggtgcca atacgatttt
    30061 tgagctcttg gcgatagcaa aattgcatgt cattgtgcca cttggtcgtg aagctagtcg
    30121 tggtgaccag attgaaaatg cagcttactt tgttaagaaa ggctatgcag aagaccttca
    30181 agaaagcgat ttgaccttgg atagtttgga agagaagctt tctcacttac taagtcacaa
    30241 ggaagattac caagctaaga tgaaagcttc taaggaattg aaatctctag cagattttta
    30301 tcaattgttg aaaaaagatt tatcataagg aaagtaaatg tcaaaagata agaaaaatga
    30361 ggacaaagaa atcctcgaag aattgaaaga gttatcagaa tggcagaaac gaaaccaaga
    30421 atatctaaaa aagaaggctg aagaagaagc ggctctagct gaggagaagg aaaaggaaag
    30481 acaagctcgg atgggagaag aatctgagaa gtcagaggac aaacaggacc aggagagtga
    30541 aacagaccag gaagattcag aatcagctaa ggaagagtct gaagaaaaag tagcatcctc
    30601 agaggctgac aaagagaaag aagagaaaga agaatcagag tctaaagaga aggaggaaca
    30661 ggataaaaag cttgctaaaa aggctacaaa ggaaaaacca gccaaagcaa agattcctgg
    30721 tatccatatc ttgcgagcct tcacgatttt atttccaagt ctgcttttat tgattgtctc
    30781 tgcctacttg ctcagtcctt atgcgaccat gaaagatatt cgtgttgagg gaacggtgca
    30841 aactacagct gatgatattc gacaggcttc aggcattcag gattcggatt atacgattaa
    30901 ccttctgcta gacaaggcaa aatatgaaaa gcagattaag tctaactatt gggttgaatc
    30961 agctcaactt gtctatcaat ttccaactaa gttcactatt aaggtcaagg aatatgatat
    31021 tgtggcctac tatatttctg gtgaaaatca ttatcctatt ctttccagtg gtcagcttga
    31081 gactagttct gtgagtctga acagtttacc agaaacttat ttatcagttc tctttaatga
    31141 tagtgaacaa atcaaggttt ttgtctcaga acttgctcaa attagcccag aactcaaggc
    31201 ggctatccaa aaggtggaat tagccccaag caaggtgaca tccgatttaa ttcgattgac
    31261 catgaatgat tcggacgaag tcttggttcc tctatctgaa atgagtaaga aactgccata
    31321 ttacagtaag attaagccac aattgtcaga accgagtgtg gtcgacatgg aagctggaat
    31381 ttacagttac actgtggcgg ataaattaat tatggaggct gaggaaaaag ccaaacaaga
    31441 ggccaaggaa gctgagaaaa aacaagaaga agaacagaaa aaacaagagg aagagagcaa
    31501 tcgaaatcaa acaaatcagc gttcatcgcg tcgctaggtt taccttttct cttatagttc
    31561 tttagtgacc atgtttttac gtttaatatt tgacatttgt ttttctttat gttacatctg
    31621 aaatgtaatc gattacaaaa taatttttga tgaagaaggt aacacatatg tcagatgaag
    31681 tattcttatt tgaagaaatt gaagaaatcg tagcccctac agatggtgaa tttttggggg
    31741 aagttttact tggaactggg gtagttctct taattggagt agcctgttgt taaaaagata
    31801 gggagtgata atcatgcaag ataacttttt atttgaggaa attgaagaaa tttcagtacc
    31861 agttagtgat ttttcagctg gacttgcaac aggtatcgga tttggtttag caatccttgc
    31921 tcttgctggt tgttgaagtt tgttcattta ctaacatcaa gctttttcaa tttcatttta
    31981 gacagtcatt tgaattttcc gtattagtct tgcagcaaga gattaataga attagtcatt
    32041 attttattga ttgcggactg agggactaga gtatgtttta cttagcccct cttttattta
    32101 ttaaaggtta ggtttgttat gagaattgtt gataagatta agatattacc tactccttat
    32161 gagggacagt atcatctata tataccatcc agtaagaaac atgtattagt tgggaaacag
    32221 gaaaaaaatg gttagagcaa ctaataggtc aagaatttac catatcggac ttattagtgt
    32281 tagtagggaa gaaatattat ttaagatttt atattgttct tagtaaaatg ggacttatag
    32341 attctatgaa atcacgaaaa aagataaat
//
LOCUS       DBEJJE010000023        32085 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEJJE010000023 DBEJJE010000000
VERSION     DBEJJE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.23"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            307..2808
                     /gene="leuS"
                     /locus_tag="ACL3F5_001055"
     CDS             307..2808
                     /gene="leuS"
                     /locus_tag="ACL3F5_001055"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0514879.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKSKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            2947..3789
                     /locus_tag="ACL3F5_001056"
     CDS             2947..3789
                     /locus_tag="ACL3F5_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514880.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            3845..4540
                     /locus_tag="ACL3F5_001057"
     CDS             3845..4540
                     /locus_tag="ACL3F5_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0514881.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            4552..4968
                     /locus_tag="ACL3F5_001058"
     CDS             4552..4968
                     /locus_tag="ACL3F5_001058"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0514882.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(5801..5875)
                     /locus_tag="ACL3F5_001059"
     CDS             complement(5801..5875)
                     /locus_tag="ACL3F5_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0514883.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDK"
     gene            6009..7007
                     /gene="ruvB"
                     /locus_tag="ACL3F5_001060"
     CDS             6009..7007
                     /gene="ruvB"
                     /locus_tag="ACL3F5_001060"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0514884.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6988..7560
                     /locus_tag="ACL3F5_001061"
     CDS             6988..7560
                     /locus_tag="ACL3F5_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGR0514885.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            7791..8549
                     /locus_tag="ACL3F5_001062"
     CDS             7791..8549
                     /locus_tag="ACL3F5_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0514886.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            8558..9361
                     /locus_tag="ACL3F5_001063"
     CDS             8558..9361
                     /locus_tag="ACL3F5_001063"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0514887.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            9383..10642
                     /gene="rseP"
                     /locus_tag="ACL3F5_001064"
     CDS             9383..10642
                     /gene="rseP"
                     /locus_tag="ACL3F5_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0514888.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETSQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            10655..12508
                     /locus_tag="ACL3F5_001065"
     CDS             10655..12508
                     /locus_tag="ACL3F5_001065"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0514889.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            12607..13986
                     /gene="bglA"
                     /locus_tag="ACL3F5_001066"
     CDS             12607..13986
                     /gene="bglA"
                     /locus_tag="ACL3F5_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0514890.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            14178..15986
                     /gene="glmS"
                     /locus_tag="ACL3F5_001067"
     CDS             14178..15986
                     /gene="glmS"
                     /locus_tag="ACL3F5_001067"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0514891.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTDGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTEDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            16258..17307
                     /locus_tag="ACL3F5_001068"
     CDS             16258..17307
                     /locus_tag="ACL3F5_001068"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0514892.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(17407..21249)
                     /gene="spuA"
                     /locus_tag="ACL3F5_001069"
     CDS             complement(17407..21249)
                     /gene="spuA"
                     /locus_tag="ACL3F5_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0514893.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAAEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            21666..22079
                     /gene="rpsL"
                     /locus_tag="ACL3F5_001070"
     CDS             21666..22079
                     /gene="rpsL"
                     /locus_tag="ACL3F5_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0514894.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            22099..22569
                     /gene="rpsG"
                     /locus_tag="ACL3F5_001071"
     CDS             22099..22569
                     /gene="rpsG"
                     /locus_tag="ACL3F5_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0514895.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22994..25075
                     /gene="fusA"
                     /locus_tag="ACL3F5_001072"
     CDS             22994..25075
                     /gene="fusA"
                     /locus_tag="ACL3F5_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0514896.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            25179..29570
                     /locus_tag="ACL3F5_001073"
     CDS             25179..29570
                     /locus_tag="ACL3F5_001073"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0514897.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMTPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLDRLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            29672..29935
                     /locus_tag="ACL3F5_001074"
     CDS             29672..29935
                     /locus_tag="ACL3F5_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0514898.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            29928..30206
                     /locus_tag="ACL3F5_001075"
     CDS             29928..30206
                     /locus_tag="ACL3F5_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0514899.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            30227..30379
                     /locus_tag="ACL3F5_001076"
     CDS             30227..30379
                     /locus_tag="ACL3F5_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514900.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            30401..31642
                     /locus_tag="ACL3F5_001077"
     CDS             30401..31642
                     /locus_tag="ACL3F5_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0514901.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFFHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            31652..31882
                     /locus_tag="ACL3F5_001078"
     CDS             31652..31882
                     /locus_tag="ACL3F5_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0514902.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(31887..>32085)
                     /locus_tag="ACL3F5_001079"
     CDS             complement(31887..>32085)
                     /locus_tag="ACL3F5_001079"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514903.1"
                     /translation="YIISKGGWYNDQPPFRFILFKPRQRRLAVYMLLTSSVLSATSKQ
                     CFEQPAASFLVCSLIFIEYQI"
BASE COUNT         9154 a         6060 c         7480 g         9391 t
ORIGIN      
        1 agattcagtc cactatacgt tcttcataaa tcaaaaagcg acataggttg tcggctattt
       61 attgtgaata cattaattag cattccagtt ttatcttcgg tctaaaataa gtattttgtg
      121 ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat gggataaaaa
      181 gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata cagtttttcc
      241 tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca aaattggaga
      301 gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg ctactgggca
      361 gaacatcata catttaagac aggaacagat gcatcaaaat ctaagtttta tgcgcttgat
      421 atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg ttatactgca
      481 accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca cccaatgggt
      541 tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa tgacccagca
      601 gaatttacag cggaaaacat tgccaacttc aaacgtcaaa tcaatgcgct tggattttct
      661 tatgactggg atcgtgaagt caatacaaca gatccaaact actacaagtg gactcaatgg
      721 attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc agtaaactgg
      781 gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg aacttctgag
      841 cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa aatcacggct
      901 tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc tatcaaggat
      961 atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa agtaaaagga
     1021 acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg tgcgactttc
     1081 actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga gcaagcagaa
     1141 gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg tacagacctt
     1201 gctaaagaaa aaacaggggt ttggactggt gcttatgcca tcaaccctgt caatggtaag
     1261 gaaatgccaa tctggattgc agactatgtc cttgctagtt atggaacagg tgcggttatg
     1321 gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga ccttccaatc
     1381 gtcgaagtac ttgaaggtgg aaatgtcgaa gaagctgcct acacagagga tggcctgcat
     1441 gtcaattcag acttcctaga tggactcaac aaagaagacg ctattgccaa gattgtggct
     1501 tgcttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg cgactggctc
     1561 tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga agatggaact
     1621 tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa ggatatccgt
     1681 ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga agtgactcgt
     1741 gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc tggttcaagc
     1801 tggtactacc tccgctatat tgatccacac aatactgaga agttggctga tgaggacctc
     1861 ctcaaacaat ggttgccagt agatatctac gtgggtggtg cagagcatgc tgttcttcac
     1921 ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt tccgactaag
     1981 gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta ccgtgaccac
     2041 cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt cttccatgta
     2101 gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct caagaacgtt
     2161 gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt ttatgaaatg
     2221 tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga aggaagccgt
     2281 aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc ggaaaacaat
     2341 ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca aattgagtct
     2401 ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc taacaaggaa
     2461 gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc atttgcacct
     2521 cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat ctcttatgta
     2581 gcttggccaa cttgggacga aagcaaattg gttgaagatg aaattgaaat tgtcgtccaa
     2641 atcaaaggaa aagttcgtgc caaactcatg gttgctaaag atctatcacg tgaagaatta
     2701 caagaaatcg ctttagctga tgaaaaagtc aaagcagaaa ttgacggtaa ggaaatcgtg
     2761 aaagtaattg cggtaccgaa taaactcgtt aatatcgtcg ttaaataacg agtttattag
     2821 ctctatctgc caccttcaat agtccactgg actattgaag ccaactaaat tagttaacat
     2881 tgttgtgaaa taaaaagaag taactctaga gtatgaactt tagagttact tttagaatag
     2941 gtcagaatga atagattagt gaacgatagc aggaagtgtg aaattttatt atttaagatt
     3001 tctattattg tagtgtcagt tatagtatta gtaatgtcaa tagtgggtgc atattatttt
     3061 aaaaattgtc tttgggacaa ggaaagttta aatttgacac tcactttaga cactctcttt
     3121 gcagttttta ttactttctt tagtttttca aatgataaat caagcaatat ttttggaata
     3181 tctccaaatg aaattataag gacacagtct gaagtgtatc aatttttatt tacaaaatct
     3241 tttgcaactc tattaatagt gacaaatttg ttatccatta ttcattattt tggagccaaa
     3301 aatttaatag tttcttttaa tgaaacttat cctcgtattc aatccagtgt tggtatcatg
     3361 tggctaccac tgtttggtat tctgataatc tattttattt ggctcttaat agagggatta
     3421 aaatatatca gaaaaataaa ttatattatt caaaataggg aaataatcta tttttattcg
     3481 caggtaaaag ttgtagataa acttactgat tctgaatcga aaaaatacgg tgaatatatt
     3541 gatttgtacg aatcgtgtcg tcagaacaat ttaagtgttc tacttaactt tcttcaaaat
     3601 tcggatgata aacgaggagt tattgctagt aactcagtga gaattatgtt tgaatctttg
     3661 gataaagcag accaaattgc ggccctgaat atttgtagaa actatgtagc acgagaaaat
     3721 gttttaaata aagaagatgc agaaaaattg ttaaatgaaa ttgataaaaa acttgaaatt
     3781 agcagatagg acaattcaaa tagagttgag taaaaagttt gaaaagtgaa acaaggagaa
     3841 agctatgcca gtaaatgaat atggtcagat gattggtgag tcaatggaag gttatacacc
     3901 cggtgcactg ccttctattg atttcttaga agggcgttat gctaggatag aggctctctc
     3961 ggtagaaaaa catgcggagg atttgctagc tgtttatggc ccggatactc ctcgggagat
     4021 gtggacctat ctttttcagg agccagtagc agatatgggg gagctggtta gccttttaaa
     4081 tcagatgttg gctcgtaagg accgttttta ctatgcaatc atagacaagg cgactggtaa
     4141 ggctttggga actttttctc tcatgcgcat tgaccagaat aaccgagtaa tagaagtcgg
     4201 agcagtcact ttttctccag agctaagggg tacacggata ggaactgagg ctcagtatct
     4261 cctagctcgc tatatttttg aggagctaaa ctatcgtcgc tacgagtgga aatgcgatgc
     4321 cttaaatctg ccatccagac gagttgcgga gcgtttggga tttgtctatg aaggaacctt
     4381 ccgccaggcg gtggtttata aggggcgtac gagagatacg gattggttgt ctatgattga
     4441 tatggactgg cctcaagtca aagatcgttt ggaaacatgg ctgcgtcctg aaaattttga
     4501 taaaaatgga cagcagtaca agagcttgag agaactttaa gaggtgttga gatgattact
     4561 attaaaaagc aagaaattgt caagctagag gatgttttgc atctctatca ggctgtcggt
     4621 tggacaaatt atacccatca accagagatg ctggagcatg ccttatcgca ttcattagta
     4681 atttatctgg cacttgatgg tgatgctgtg gtgggcttga ttcgtttggt tggagatgga
     4741 ttctcatcag tttttgtaca ggatttgatt gttttaccaa tctatcagcg tcaagggatt
     4801 ggtagtgccc taatgaaaga ggccttaaaa gattacaaag atgcttatca agtccagctg
     4861 gtgacagaag agacagaaaa aaacgtggga ttttatcgtt ctatgggctt tgaaatctta
     4921 tccacctata attgtatagg gatgacttgg gcgaatcgag aaaaataaca aaacttgttt
     4981 tttcttaagc aaaatttaag gatggtctag tattatataa tcattaaata aagacctcct
     5041 aactttattt aataaaatcc taaacttttt tcatcacaat ctcctaatga agccacccaa
     5101 tcaggtggct tttttgcgtg gtgaggtgct ggtgatagaa attttttgca aaatagtaaa
     5161 attttagaaa agttaaggta gttttaagtt tcgtcttgta tcatgtagtt attaaataaa
     5221 gacctcctaa ctttatttaa taaaatccta aacttttctt tttcataata atctccctta
     5281 actccaccca atcaggtgga gttttttagc tctatttcag gcttttgggg actattctaa
     5341 aaataatttt tcgatatttt tcggtatttt tcggattttg gtcggggaat tggcggggac
     5401 ttttttagcg aatataacta agaaataggt ctgtggtcgc ttcagctagt tcaaactcaa
     5461 tttgattgta agtgactgtt aattgaagaa ctggaactac tgtaataatg attttgcttg
     5521 tctagtagtg gcgtattaaa tgagaagtga catgtaagat tgtctcttcg tttacgaaat
     5581 caaaatttct atgaaattga tagaatccct aacgttctct taatcttaac cgtcttgtcg
     5641 tacagcggtt gaagaaaatg taaacctttg acaaaattcg tgaactatgg gataataaag
     5701 aggaattgag tactagttct atatcatagg ctagaaaaga ccccaagctc acgaccaaat
     5761 aagcttgagg tcttttttga cactatttgt ccttgtttag ctatttatcg actatacgaa
     5821 gaacgacacc gaccacaatt ggtccgatga tagttttgag tactaattcc atcatgggct
     5881 atctcacctc ctttcgtagg cggtgtagca gtgtcgtaga atattatacc acataagtgc
     5941 taaacttagg agtcacccaa tcaggtggct tttttgtttg tggcttggtt ttttgatata
     6001 atagagccat gagtagaatt ttagataatg agataatggg ggatgaggag ttagtagaac
     6061 gcacgctccg tcctcagtat ttacgtgaat atatcggaca ggataaggtc aaggaccagc
     6121 tacaaatctt tattgaagct gccaaaatgc gggatgaagc gctggatcat gtgctcttat
     6181 ttgggcctcc aggtctcggg aaaacgacca tggcctttgt tattgccaac gaactgggag
     6241 tcaatcttaa gcagacgtcg ggtccagtca ttgaaaaagc cggagatctg gtagctattt
     6301 tgaatgagtt agagcctggg gatgtacttt ttattgatga gatccatcgt ttgccaatgt
     6361 cagtggaaga ggtgctttat agtgctatgg aggacttcta catcgatatt atgattgggg
     6421 ctggtgaggg tagtcgtagt gttcatttgg agttaccacc ttttaccttg attggtgcga
     6481 cgactcgggc tggtatgctc tccaatccgc tacgggcacg ttttgggatt acaggccata
     6541 tggagtatta tgcccatgct gacttgacag aaattgtcga gcggacggca gatatttttg
     6601 agatggaaat cactcatgag gcagcatctg agttggccct acgtagtcgt gggacccctc
     6661 gtattgccaa tcgtctcctc aagcgcgtgc gcgattttgc ccagataatg gggaatgggg
     6721 taattgatga tattattacc gataaggctt tgactatgct ggatgttgac catgaaggtt
     6781 tggactatgt ggatcaaaaa atccttcgta ccatgattga gatgtacagt ggaggacctg
     6841 ttggtctagg aactctttct gtgaatatcg ccgaagagcg tgagacagtt gaagatatgt
     6901 atgagcctta cttgattcaa aaaggtttta tcatgcggac acggtctgga cgggtggcga
     6961 ctgctaaggc atatgagcac ttaggttatg aatacagtga aaaataagca agaaatctta
     7021 gaggctttta gagaaagtcc agatatgatg gccattctga cgatcatccg agaccttggt
     7081 ttgaaagact cgtggttggc agcaggttct gtcagaaatt tcatctggaa tcttttgtca
     7141 gacaaatccc cttttgatca tgaaacagat atagatgtga ttttctttga tccagatttt
     7201 tcttatgagg aaaccttatt actggagaaa aagctgagag aggattttcc tcagtaccag
     7261 tgggaattga aaaatcaggt ctatatgcat cagcacagtc ctcacactgc ttcctatacc
     7321 agttctcgtg atgctatgag taagtatcca gaacggtgta cggcagttgg actgcgcttg
     7381 aatgaagaat cagattttga actctatgta ccttatggtt tggaggatat tttgaatttt
     7441 caagttcgtc caactcctca tttcttagaa aatgaagacc gaatggaact ctatcaaaca
     7501 cgtttatcca agaaaaattg gcaggagaaa tggaaaaatt tgatttttaa aaatacttaa
     7561 ggaaacttta agctagggag tgtacactaa gttcataagt taagaagacc ttaacttaaa
     7621 ctcctaaaac tttttcataa taatctccct ataaaaataa agtcgcccaa tcaggcggct
     7681 tatttttttg aaaaatgggc ttggtgcctg agaataaata gcttagtgat agaagaaaat
     7741 ggggaaatat ggtataatga aacgatagat ttttgaatag gaataagatc atgtttggat
     7801 tttttaagaa agataaggct gtggaagtag aggttccgac acaggttcct gctcatatcg
     7861 gcatcatcat ggatggcaat ggccgttggg ctaaaaaacg tatgcaaccg cgagtttttg
     7921 gacataaggc gggcatggaa gcattgcaaa ccgtgaccaa ggcagccaac aaactgggcg
     7981 tcaaggttat tacggtctat gctttttcta cggaaaactg gacccgtcca gatcaggaag
     8041 tcaagtttat catgaacttg ccagtagagt tttatgataa ttatgtcccg gaactacatg
     8101 cgaataatgt taagattcaa atgattgggg agacagaccg cctgcctaag caaacctttg
     8161 aagctttaac caaggctgag gaattgacta agaacaacac aggattgatt cttaattttg
     8221 ctcttaacta tggtggacgt gctgagatta cacaggcgct taagttgatt tcccaggatg
     8281 ttttagatgc caaaatcaac ccaggtgaca tcacagagga attgattggt aactatctct
     8341 ttactcagca tttgcctaag gacttacgag acccagactt gattatccgt actagtggag
     8401 aattacgttt gagcaatttc cttccatggc agggagccta tagtgagctt tattttacgg
     8461 acaccttatg gcctgatttt gacgaagcgg ccttgcagga agctattctt gcctataatc
     8521 gtcgtcatcg ccgatttgga ggagtttagg aggaaatatg acccaggatt tacagaaaag
     8581 aaccttgttt gcagggattg ccctggctat tttcctacca attttaatga ttgggggcct
     8641 cttgcttcag atagcaatcg gaatcatagc catgctagcc atgcatgaac ttttgaagat
     8701 gagaggtcta gagaccatga cgatggaggg cctcttgacc ctctttgcaa cctttgcatt
     8761 gaccattccc ttggagaatt acctgacttt tttgccagtt gatgggaatg tggttgccta
     8821 tagtgttttg atttcaatca tgttaggaac gaccgttttt agcaagtctt atacgattga
     8881 ggatgcggtt ttccctcttg ctatgagctt ctacgtgggc tttggattta atgctttact
     8941 agatgctcgt gttgcaggtt tggacaaggc tctcttagcc ttgtgtatcg tctgggcgac
     9001 agacagtggt gcctatcttg ttgggatgaa ctatgggaaa cgaaagttag caccaagggt
     9061 atcgcctaat aaaacccttg agggtgcctt gggtggtatt ttaggagcaa ttttagtaac
     9121 cattatcttt atgatagttg acagtacagt tgctcttcca tatggaattt acaagatgtc
     9181 agtctttgct attttcttta gcattgctgg acaatttggt gatttactag aaagttcgat
     9241 caaacgtcat tttggtgtta aggattctgg gaaatttatc cctggacatg gtggtgtttt
     9301 ggatcgtttc gatagtatgt tgcttgtatt tccaatcatg cacttatttg gactctttta
     9361 atcaaaagac ggaggaaaca ctatgcttgg aattttaacc tttattctgg tttttgggat
     9421 tattgtagtg gtgcacgagt tcgggcactt ctactttgcc aagaaatcag ggattttagt
     9481 acgtgaattt gccatcggta tgggacctaa aatctttgct cacattggca aggatggaac
     9541 ggcctatacc attcgaatct tgcctctggg tggctatgtc cgcatggccg gttggggtga
     9601 tgatacaact gaaatcaaga caggaacgcc tgttagtttg acacttgctg atgatggtaa
     9661 ggttaaacgc atcaatctct caggtaaaaa attggatcaa acagccctcc ctatgcaggt
     9721 gacccagttt gattttgaag acaagctctt tatcaaagga ttggttctgg aagaagaaaa
     9781 aacatttgca gtggatcacg atgcaacggt tgtggaagca gatggtactg aggttcggat
     9841 tgcaccttta gatgttcaat atcaaaatgc gactatctgg ggcaaactga ttaccaattt
     9901 tgcaggccct atgaacaatt ttatcttagg tgtcgttgtt ttttgggttt taatctttat
     9961 gcagggtggt gtcagagatg ttgataccaa tcagttccat atcatgcccc aaggtgcctt
    10021 ggccaaggta ggagtaccag aaacgtcaca aattactaag attggctcac atgaggttag
    10081 caactgggaa agcttgatcc aagctgtgga aacagaaacc aaagataaga cggcaccgac
    10141 tttggatgtg actatttctg aaaaggggag tgacaaacaa gtcactgtta cacccgaaga
    10201 tagtcaaggt cgttaccttc taggtgttca accgggggtt aagtcagatt ttctatccat
    10261 gtttgtaggt ggttttacaa ctgctgctga ctcagctctc cgaattctct cagctctgaa
    10321 aaatctgatt ttccaaccag atttgaacaa gttgggtgga cctgttgcta tctttaaggc
    10381 aagtagtgat gctgctaaaa atggaattga aaatatcttg tacttcttgg caatgatttc
    10441 catcaatatt gggattttta atcttattcc gattccagcc ttggatggtg gtaagattgt
    10501 gctcaatatc ctagaagcca tccgccgcaa accattgaaa caagaaattg aaacctatgt
    10561 caccttggcc ggagtggtca tcatggttgt cttgatgatt gctgtgactt ggaatgacat
    10621 tatgcgactc ttttttagat aatcgaggaa tattatgaaa caaagtaaaa tgcctatccc
    10681 aacgcttcgc gaaatgccaa gcgatgctca agttatcagc catgctctta tgttgcgtgc
    10741 tggttatgtt cgccaagttt cagcaggtgt ttattcttat ctaccacttg ccaaccgtgt
    10801 gattgaaaaa gctaaaaaca tcatgcgcca agaattcgaa aagattggtg ctgttgagat
    10861 gttggctcca gcccttctta gtgcagaatt gtggcgtgaa tcaggtcgtt acgaaaccta
    10921 tggtgaagac ctttacaaac taaaaaaccg tgaaaaatca gactttatct taggtccaac
    10981 tcacgaagaa acctttacag ctattgtccg tgattctgtt aaatcttaca agcaattgcc
    11041 actcaacctt tatcaaattc agcccaagta tcgtgatgaa aaacgcccac gtaatggact
    11101 tcttcgtaca cgtgagttta tcatgaagga tgcttatagt ttccacgcta actatgatag
    11161 tttggatagt gtttatgatg agtacaaagc agcctatgag cgtattttca ctcgtagtgg
    11221 tttagacttc aaggctatta ttggtgacgg tggagccatg ggtggtaagg atagccaaga
    11281 atttatggcc attacatctg ctcgtacaga ccttgaccgc tgggttgtct tggacaagtc
    11341 agttgcctca tttgacgaaa ttcctgcaga agtgcaagaa gaaatcaagg cagaattgct
    11401 caaatggata gtctctggtg aagataccat tgcttactca agtgagtcta gctatgcagc
    11461 taacttagaa atggcaacaa acgagtacaa accaagcaac cgtgttgtcg ctgaagaaga
    11521 agttactcgt gttgcaacgc cagatgttaa atcaattgat gaagttgcag ccttcctcaa
    11581 tgttccagaa gaacaaacga ttaaaaccct cttctacatt gcagatggcg agcttgttgc
    11641 agcccttcta gttggaaatg accaactcaa cgaagtcaag ttgaaaaatc acttgggagc
    11701 agatttcttt gacgttgcta gcgaagaaga agtggcgaat gttgttcaag caggatttgg
    11761 ttcacttgga ccagttggtt tgccagagaa tattaaaatt attgcagatc gtaaggtaca
    11821 agatgttcgc aatgcagttg tcggtgctaa cgaagatggc taccacttga ctggtgtgaa
    11881 cccaggccgt gattttactg cagaatatgt ggatatccgt gaagttcgtg agggtgaaat
    11941 ttccccagat ggacaaggtg tccttaactt tgcgcgtggt attgagatcg gtcatatttt
    12001 caaactcgga actcgctatt cagcaagcat gggagcagat gtcttggatg aaaatggtcg
    12061 tgctgtgcca atcatcatgg gatgttacgg tatcggtgtc agccgtcttc tttcagcagt
    12121 gatggagcaa cacgctcgcc tctttgttaa caaaacgcca aaaggtgaat accgttacgc
    12181 ttggggaatc aatttcccta aagaattggc accatttgat gtgcatttga ttactgtcaa
    12241 tgtcaaggat gaagaagcgc aagccttgac agaaaaactt gaagcaagct tgatgggagc
    12301 tggttatgaa gtcttgacag atgaccgtaa cgaacgtgtc ggtgttaaat ttagcgatag
    12361 tgacttgatt ggtcttccaa tccgtatcac tgttggtaaa aaagcggccg atggcattgt
    12421 agaagttaag atcaaggcaa ctggtgacac cattgaggtt catgcagata acgtgcttga
    12481 aacgcttgaa atcctaagca agaaataaaa actataatca gaagaaaaac aaggaaaaaa
    12541 tgtaactagt ttttaccttg ttttttctgt ataatgggag aaatgagtag ataaagaggt
    12601 aaatgtatgc taagatttcc aaaggatttt gtctggggat cctctacttc tggaccgcag
    12661 acagaaggac gtgtagctgg tgacggtaag ggagacaatc tctgggatta ctggttccaa
    12721 gtggagccaa atcgttacta taatgggatt ggttcagata agacatcgac tttttatgaa
    12781 aattgggagc gggatattga gcttttgtta gagactggtc acacagcctt tcggacttct
    12841 attcagtggt cacggatttt tccacaaggc tgtggaaaag tcaacactca aggtgtggat
    12901 ttttatcgta aggtctttga ggctattaag gctaaaggaa ttcgtctgtt agtcaatctc
    12961 tatcattttg atttaccttt tgcccttcaa gaggatggtg atggttggga aaataaggcg
    13021 acagtctcag cctatgaaga ctatgctcgt ttttgttttg agacttatgg agatttagtg
    13081 gatcaatgga ttacctttaa cgagcccatc gttcctgtag aatttggtta tttttatgat
    13141 gcccattatc cacataaggt ggatgcagag gcagctgtta aggtagccta tcatacacaa
    13201 ttggccagca gccgggctgt taaggcttgc catgaacttt tgcctgattc caagattggg
    13261 attgtcctca acttgacacc ggcttatcca cgtagccagc atcctgctga tgtcaaggca
    13321 gctcgtattg cggccctttt tcaggcccaa tctttcttag atccatctgt cttggggact
    13381 tatccacagg agttggtaga aatcttgcat gaacacggtc ttttacctga tgctacagag
    13441 gaagagttgg aactcattcg tgataatacg gtggacttcc ttggtgtgaa ctactatcaa
    13501 cctttgcgtg ttatggctcc tcgatttgct aagcatccag agagtccact cttaccagaa
    13561 catttttacg agccttatgt gatgcctgga cgtaaaatca attctcaccg tggttgggag
    13621 atttatgagc aagggattta tgacatcgcc caaaatatca aggaaaatta tggcaatatt
    13681 gaatggatgt tgactgagaa tggtatgggt gttgaagggg aagaaaaatt ccgtcaagat
    13741 ggaatgattc aagatgatta ccgtattgac tttgtaaaag gtcatcttcg tgaacttcac
    13801 cgtgccattg aagatggtgc caactgtaag ggctacttga tttggacctt tattgactgc
    13861 tggtcatggc tcaacagcta taaaaatcgc tatggtttgg tcgaattaga cttggaaacg
    13921 caagaacgtc gtctgaagaa atcaggccac tggttcaaaa aattaagcga taataatgga
    13981 ttttaaaaag gactctgact gattatccca atcggtcaga gttttttgct tacaggagct
    14041 taatttgaac tataccaatt tttactcttg acaagtgaaa gaaacaagta tatactgttt
    14101 ttgctgattc tataaaagat gaattagact ataccaattt taaggagaaa gcacagcttg
    14161 cctgtgtcgt atatactatg tgtggaattg ttggtgttgt tggaaacaca aatgcaactg
    14221 atattttgat tcaagggctt gaaaagcttg aataccgtgg ctatgattct gcgggaattt
    14281 ttgtcctaga tggtgctgat aaccatttgg tgaaggctgt tggtcgtatt gcagaattgt
    14341 ctgccaagac agatggtgtt gagggaacaa ctggtatcgg acatactcgt tgggctactc
    14401 acggaaaacc aactgaggac aatgctcacc cacaccgctc tgagacagaa cgttttgtct
    14461 tggtgcataa tggggtgatt gagaactacc ttgaaatcaa ggaagaatac cttgcaggtc
    14521 accacttcaa ggggcagaca gatactgaaa tagccgttca tttgattgga aaatttgcgg
    14581 aagaagaagg gctctcagtt cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt
    14641 cttatgcctt tgccttggtt gactcacaag atcctgaagt catctacgta gctaaaaata
    14701 aatcaccact tttgattggt cttggagaag gctataacat ggtctgctca gacgccatgg
    14761 ctatgattcg tgaaactaac caatacatgg aaatccatga ccaagagttg gtaatcgtca
    14821 aggctgatag tgtggaagtt caagactatg atggaaatcg tcgtgagcgt gctagctaca
    14881 ctgctgaact tgacttgtca gatatcggta agggaactta cccttactac atgctcaagg
    14941 aaattgacga gcaaccaact gttatgcgga aactcatcca agcctacaca gatgaggctg
    15001 gtcaagttgt cgtagaccca gatatcatta aggctgttca agacgcagac cgcatctaca
    15061 tccttgcagc tggaacatct taccatgcag gatttgcttc taagaaaatg ttggaagaat
    15121 tgacagatac accagttgaa cttggaatct catctgagtg gggctacggt atgccacttc
    15181 tcagcaagaa accactcttc atctttatca gccaatctgg tgaaacagcg gatagtcgtc
    15241 aagttttggt caaggctaat gaaatgggaa ttccaagctt aacagtgaca aatgttccag
    15301 gttcaaccct ctcacgtgaa gccaactata ccatgctcct tcatgcaggt cctgaaattg
    15361 ctgtggcatc aactaaagcc tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag
    15421 cagtcggaga agcaaatggt aatgctaaag cgcaagtctt tgatctggtt catgaattgt
    15481 caatcgtagc tcagtctatc gaatcaactc tttcagagaa agaaaccatt gaagtcaagg
    15541 ttcgtgaact tcttgaaaca actcgtaacg ccttttacat cggacgtggt caagattact
    15601 acgtagccat ggaagcaagt ctcaaactca aagagatttc ttatatccag tgtgaaggct
    15661 ttgctgcagg agaactcaag cacggaacca ttgccttgat tgaagaagga acgcctgtct
    15721 tgtctctctt gtcagatcca gttcttgcca accatactcg tggaaatatc caagaggtcg
    15781 cagcccgtgg tgccaaagtc ctcactatcg cagaagagaa tgtagccaaa gataccgaag
    15841 atatcgtcct tacgaccgta catccatacc tctcaccaat ttcaatggtc gtaccaacgc
    15901 aattagtcgc ttactttgca accctccacc gtggcctcga tgtggacaaa ccacgtaacc
    15961 ttgccaagtc agtaacggta gaataagcta aaaaagtcta gttatctagg cctttttctt
    16021 gtgagcaaat tggttgcttg tactcaagat tcgtgttata ctcttcgaaa atctcttcaa
    16081 accacgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa
    16141 cctcaaaaca ctgttttgag cagcctgcag ctagcttcct agtttgctct ttgattttca
    16201 ttgagtatta gaataatttt tcaaattgaa gtacagagat agataaggag aatcacaatg
    16261 gtagaattgg gaatttcaac atttggggaa ataacggagc ttgaagggac tggacaaact
    16321 tacagtcatg ctgaacgcat tcgccagttg gtggcagaga ttgagctggc tgacaaggtt
    16381 ggtttggatg tatatgggat tggtgagcac catcgggcgg attttgcagt atcagcccca
    16441 gagattgttc tggccgctgg ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc
    16501 agcattctgt caagcatgga cccgattcgt ttgttccaac agtatgccac tatcgatgct
    16561 ttgtcaaatg gacgagcgga gattatggct ggaaggggct ctttcacgga atctttccct
    16621 ctgtttggtt atgacttgaa agactacgac tctctttttg atgagaaatt agacttgctt
    16681 cagttagtca atgaaaagac caagttagac tggcaaggtc gattgactca aacgattgct
    16741 ggtaaagaag tttatcctcg tccagttcag gacaaattgc ccttgtggat agctacaggt
    16801 ggtcatgtcg aatcaacagt gaagattgct caggctggtc taccgattgt atatgctatt
    16861 attggtggta atccacgtta ttttaaaaag ttgattcagg cttatcgtga gattggaagc
    16921 gaagcgggtc atgctgacaa agacttgaaa gtgggagccc attcttgggg gtggattgcg
    16981 gaagatggtg agcaggcggt gaaagattat ttccatccga ctaagcaagt ggtggatgct
    17041 atttccaaag accgtccgca ctggcaggaa ttgcgttatg agcaatattt ggagcaggta
    17101 gggccaaatg gcgccatgtt tgttggcaat ccagatcagg tggccgaaaa attgattcgc
    17161 atgatagagg atttaggatt ggaccgcttc atgcttcatc taccgcttgg ttctatgcct
    17221 catgaccagg ttctgagagc tattgaactc ttcggaacac aagttgcacc caaagtacga
    17281 gcttattttg ctatgaaaga ggcttaataa aaaatcctaa tcaagtttat taggacaaca
    17341 aatattgtac gaaaattaat cccccgagct ataatgcttg ggggattttt ctataggagg
    17401 gctagtttag ttctcttttt tattttttag taagaaaccg agaccaagga gcgcaaggag
    17461 gctgattcct gcaaatagga gtttgttttc gtttttgatt cctgtatttg gaagttcagc
    17521 ttgtctatct ggggttgcag gtatattttt cttgctagag ttttctaccg attcgttttg
    17581 aaccgcttct tttacagatg atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc
    17641 agctgtagct tggctaggtt tattttccgc atcagctact ttggcatctg gtttagtaga
    17701 atcaggtcta gcttctggag ctgggtcttg atgtgcaggg tgagaagctt cattttgatg
    17761 ttcaggcttg gaaggggttg agtctggttt ctctgctgca gttgactcat ggctagttcc
    17821 attttgagag actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt
    17881 ccattcaagt cctttcgggt tggcaattcc gactggtcct gcttggtttt catctgccaa
    17941 aacttccgca tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc
    18001 atccgcattg acaaagactg cgtagatatc gccgtttgga gcagtgattt ggtagccaat
    18061 cactacatcc tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc
    18121 tttgatatct tgaagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa
    18181 acctttcata tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt
    18241 agtccagtca aacttgttga ctgcatcgct agaatcgtaa gaatcatgga tgaagtaagg
    18301 atagtcaaat gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc
    18361 ctctgctact ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg
    18421 accggagtgg ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa
    18481 acgacggtgg atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc
    18541 aatgatgtca aagagggtca agttatcatg ggctgcgatg tattggatga catctccagg
    18601 gctgtcagct tcaaagttag ttggttgagc aatgagattt ttaaagatgg tgttgacatc
    18661 acgcttgcca cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt
    18721 gttacggatg tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc
    18781 agcagcttta gtaggcatgt tttcatcacc ggcataggtt ctccaacctt cgcctaacat
    18841 gattagattt ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag aagcggcgtc
    18901 atggtctccc atcatatcga agcggaagcc atccactttg taggtatcaa ctaggtattt
    18961 gatagagtca actaggagcc gtttggtcat atggtgggtt gtccccaagc gtccaccacc
    19021 aaagctagtt cgaggtgtgc catcggcatc cataaagtgg tagtagtttg gctctaggtc
    19081 ttcaaagata tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc
    19141 acgtttgtgg atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt
    19201 aggatcgctt gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt
    19261 gtagttgctg ttgcttgaag catagtcaga caagcgttca tggtttttca attcattgac
    19321 aaagtagtaa gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata
    19381 gtctagtttt tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat
    19441 ggcaggatct gaagtgaagt cacgcacatg agcttcgtag ataacggcgt cttcacgagt
    19501 cttgaaattg tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac
    19561 aaaggcggct ttagccactt tatgggcatc gtcaatcttg gcatcgtcgc tattccaagc
    19621 agcaagagat ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg
    19681 gtattgataa tagtagccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt
    19741 ttgtttccaa gttcctcttt cccctttttc gagagcgaca gttccaacta ctttgtcagg
    19801 gtcattcttg tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa
    19861 atcaacttgt tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt
    19921 ctcatctttc aggcgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt
    19981 ataaggatgt tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc
    20041 gattgcaaca tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt
    20101 gaggatatct tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt
    20161 gcctacgtgt tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat
    20221 cgattcatca tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata
    20281 attttcttta cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc
    20341 aaattctctt gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc
    20401 cgtaaagtct gttccgtcag gccattgagc gctacttgga ttttttacat ctccccagta
    20461 ccagagagat ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc
    20521 tgcaggctgt ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cttcgttcat
    20581 ttttggaact agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt
    20641 gatgaggaag ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc
    20701 gtagtcatct ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg
    20761 tttttcaaca tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt
    20821 tttgacatgg atacggaagt agttatcttc gatgggctct tctgccttag tttcagttgt
    20881 tactggacta gtagaagtag ttggctcact tgaacgatct tgtccagttt gtggtgctgg
    20941 atcggctggg cttgcagcag gtttttcttc tgttttctct agggaagcgt ttgcatttct
    21001 aggtgaagaa atatcacttt cgttcttacc agagccagct gctgtatcag taagaggttg
    21061 ggcaagggtg gttgtatttc tgttgttggg ttcgttagtg gttggtgtac tttcgtcgga
    21121 tgagatagtt ggtgtagcca tggcaagcaa gacaaggctt gcgccgataa ggacagaacc
    21181 agttccattt ttgagggaac ggatgctgta gaccattttt ttctcagtgt gagatggtgt
    21241 ttttctcata atgattctcc aatcaataaa tttctatatc agtatagcat gtagtaaaac
    21301 aatatgcgag cgttttcttt gatttgtgaa aaaaattcct acttttgaga agttttctgt
    21361 actattttat atatcagtat aaatgacgga gataaaaatg tcacataagc caagccgtat
    21421 tattagggag atgatgtgtt accagctatt tttattcaga aattgatctc taacattacc
    21481 aataaaaaag aaaaatatct tgacaagcaa gggaaaattt tgttacaata atagacggta
    21541 ctttttactt ttggtctctc aagagtgtac agggacgtgc tgacaaatgt tgcaaaagta
    21601 cacacagatg atatctgtca ccaagtgtat catcaccaaa aataaaaaaa cacaggagaa
    21661 tgtagatgcc tacaattaac caattggttc gcaaaccgcg taaatcaaaa gtagaaaaat
    21721 ctaaatcacc agctttgaac gttggttaca atagtcataa aaaagttcaa acaaacgttt
    21781 cttcaccaca aaaacgtggt gttgcaactc gtgttggaac aatgacacct aaaaaaccta
    21841 actcagccct tcgtaaattc gctcgtgtac gtttgagcaa ccttatcgaa gttactgcct
    21901 acatcccagg tatcggacac aacttgcaag agcacagcgt ggtgcttctt cgcggtggac
    21961 gtgtaaaaga ccttccaggg gtacgttacc atatcgtccg tggtgcactt gatactgcag
    22021 gtgttaacga tcgtaaacaa ggccgttcta aatacggtac taaacgtcca aaagcataag
    22081 gaaaggggat aaagagaaat gagtcgtaaa aatagagctc caaaacgtga cgtattgcca
    22141 gatccgctat acaattcaca actagttact cgtcttatca accgcgttat gcttgatggt
    22201 aaacgtggta ctgctgcttc aatcgtttac ggtgcttttg agcaaatcaa agaagctact
    22261 ggcaacgatg cacttgaagt atttgaaaca gctatggaaa acatcatgcc tgtacttgaa
    22321 gtacgtgcac gtcgtgttgg tggttctaac taccaagtcc cagttgaagt tcgtccagaa
    22381 cgtcgtacaa cacttggact tcgttggttg gtaacaatcg ctcgtcttcg tggtgaacac
    22441 acaatgcaag accgtcttgc aaaagaaatc ttggatgctg ctaacaacac tggtgcagct
    22501 gttaagaaac gtgaagatac tcaccgtatg gctgaagcta accgtgcatt cgcacacttc
    22561 cgttggtaag ataggatgcg aaagcgttaa gaaagtccca gagaaaatag ggaatcgaag
    22621 caggttgcgg ttgcaaccaa tgagattcat ctttttctcc agacttttag cttgagctca
    22681 actaaatcat gatgctaggc acggtaagga tgcaaggtga aaataggaaa ctgacgcagt
    22741 attcgatgaa tacaaggagt tttatctttt tcacgcagca tcccgttcca gctcatatcg
    22801 gctaactaac tttagcccgg gttcaaatta gctaaatcga ttagtattag ctataactca
    22861 gcttaccatc tcgtaagttg aaaccaacaa tagcatgaaa acattgagaa cgggtaggtc
    22921 ctgcctatcc gtttttatta aaatcgtgtt ataatagaat agaaatcaaa aataaatagg
    22981 agaaacaaac ctcatggcac gcgaattttc acttgaaaaa actcgtaata tcggtatcat
    23041 ggctcacgtc gatgccggta aaacaacaac tactgagcgt attctttact acactggtaa
    23101 aatccacaaa atcggtgaaa ctcacgaagg tgcgtcacaa atggactgga tggagcaaga
    23161 gcaagaacgt ggtatcacga tcacatctgc tgcgacaaca gctcaatgga acaaccaccg
    23221 cgtaaacatc atcgacacac caggacacgt ggacttcaca atcgaagtac aacgttctct
    23281 tcgtgtattg gatggtgcgg ttaccgttct tgactcacaa tcaggtgttg agcctcaaac
    23341 tgaaacagtt tggcgtcaag caactgagta cggagttcca cgtatcgtat ttgccaacaa
    23401 aatggacaaa atcggtgctg acttccttta ctctgtaagc acacttcacg atcgtcttca
    23461 agcaaatgca cacccaatcc aattgccaat cggttctgaa gatgacttcc gtggtatcat
    23521 tgacttgatc aagatgaaag ctgaaatcta tactaacgac cttggtacgg atatccttga
    23581 agaagacatc ccagctgaat accttgacca agctcaagaa taccgtgaaa aattgattga
    23641 agcagttgct gaaactgacg aagaattgat gatgaaatac ctcgaaggtg aagaaatcac
    23701 taacgaagaa ttgaaagctg gtatccgtaa agcgactatc aacgttgaat tcttcccagt
    23761 attgtgtggt tcagccttca aaaacaaagg tgttcaattg atgcttgatg cggttatcga
    23821 ctaccttcca agtccacttg acatcccagc aatcaaaggt attaacccag atacagacgc
    23881 tgaagaaatt cgtccagcat ctgacgaaga gccatttgca gctcttgcct tcaagatcat
    23941 gactgaccca ttcgtaggtc gtttgacatt cttccgtgtt tactcaggtg ttcttcaatc
    24001 aggttcatac gtattgaata cttctaaagg taaacgtgaa cgtatcggac gtatccttca
    24061 aatgcacgct aacagccgtc aagaaatcga cactgtttac tcaggtgata tcgctgctgc
    24121 cgttggtttg aaagatacta caactggtga ctcattgaca gatgaaaaag ctaaaatcat
    24181 ccttgagtca atcaacgttc cagaaccagt tatccaattg atggttgagc caaaatctaa
    24241 agctgaccaa gacaagatgg gtatcgccct tcaaaaattg gctgaagaag atccaacatt
    24301 ccgcgttgaa acaaacgttg aaactggtga aacagttatc tcaggtatgg gtgaacttca
    24361 ccttgacgtc cttgttgatc gtatgcgtcg tgagttcaaa gttgaagcga acgtaggtgc
    24421 tcctcaagta tcttaccgtg aaacattccg cgcttctact caagcacgcg gattcttcaa
    24481 acgtcagtct ggtggtaaag gtcaattcgg tgatgtatgg attgaattta ctccaaacga
    24541 agaaggtaaa ggattcgaat tcgaaaacgc aatcgtcggt ggtgtggttc ctcgtgaatt
    24601 tatcccagcg gttgaaaaag gtttggtaga atctatggct aacggtgttc ttgcaggtta
    24661 cccaatggtt gacgttaaag ctaagcttta tgatggttca tatcacgatg tcgactcatc
    24721 tgaaactgcc ttcaagattg cggcttcact ttcccttaaa gaagctgcta aatcagcaca
    24781 accagctatc cttgaaccaa tgatgcttgt aacaatcact gttccagaag aaaaccttgg
    24841 tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgta gatggtatgg aagcacacgg
    24901 taacagccaa atcgttcgtg cttacgttcc acttgctgaa atgttcggtt acgcaacagt
    24961 tcttcgttct gcatctcaag gacgtggtac attcatgatg gtatttgacc actacgaaga
    25021 tgtacctaag tcagtacaag aagaaattat taagaaaaat aaaggtgaag actaatccgt
    25081 cctcactcta gaaggaagtc acttagtggc ttccttttgt ctttagaaaa tacctctaaa
    25141 tatggtaaaa tagtagaaga ataatgtgag gaaaatgaat gtcaaatagt tttgaaattt
    25201 tgatgaatca attggggatg cctgctgaaa tgagacaggc tcctgcttta gcacaggcca
    25261 atattgagcg agttgtggtt cataaaatta gtaaggtatg ggagtttcat ttcgtatttt
    25321 ctaatatttt accgattgaa atctttttag aattaaagaa aggtttgagc gaagaatttt
    25381 ctaagacagg caataaagct gtttttgaaa ttaaggctcg gtctcaagaa ttttcaaatc
    25441 agctcttgca gtcctactat agggaagctt tctctgaagg tccatgtgct agtcaaggtt
    25501 ttaagtccct ttatcaaaat ttgcaagttc gtgctgaggg taatcagcta tttattgaag
    25561 gatctgaagc gattgataag gaacatttta agaagaatca tcttcctaat ttagccaaac
    25621 aacttgaaaa gtttggtttt ccaactttta actgtcaagt cgagaagaat gatgtcctga
    25681 cccaagagca ggaagaggcc tttcatgctg aaaatgagca gattgttcaa gctgccaatg
    25741 aggaagcgct ccgtgctatg gaacaactgg agcagatgac acctcctcca gcggaagaga
    25801 aaccagtctt tgattttcaa gcgaaaaaag ctgcagctaa acccaagctg gataaggcgg
    25861 agattactcc tatgatcgaa gtgacgacag aggaaaatcg tctggtattt gaaggggttg
    25921 tttttgatgt ggagcaaaaa gtgactagaa caggtcgtgt tttaatcaac tttaaaatga
    25981 cggactatac ttcaagtttt tctatgcaaa agtgggttaa aaacgaggaa gaggcccaga
    26041 agtttgacct catcaagaag aattcttggc tccgagttcg agggaatgtg gagatgaata
    26101 acttcacacg cgatttgact atgaacgtac aggatctgca ggaagttgtt cactatgagc
    26161 ggaaggattt gatgccagaa ggtgagcgtc gggttgagtt tcatgctcat actaacatgt
    26221 cgactatgga tgctttgcca gaggtcgaag agattgttgc aacagctgct aagtggggac
    26281 acaaggcggt tgctatcacg gaccatggga atgtccagtc ctttccacat ggctataagg
    26341 cggctaagaa agcgggaatc cagctgatct atggaatgga agccaatatc gtggaggacc
    26401 gtgtccctat cgtctataac gaagtggaga tggacttgtc agaagcaacc tacgtggtct
    26461 ttgacgtgga aacgacggga ctttcagcta tctataatga cttgattcag gttgcggcct
    26521 ctaagatgta caaggggaat gttattgctg aatttgatga atttatcaat cctgggcatc
    26581 ccttgtcagc ttttactaca gagttaactg gaattacaga tgatcatgtc aaaaatgcca
    26641 aaccactaga acaagttttg caagaattcc aagaattttg caaggatacg gtcctagttg
    26701 cccacaatgc tacctttgac gttggcttta tgaatgctaa ttatgagcgt catgatcttc
    26761 caaagattag tcagccagtt attgatacgc tggagtttgc tagaaacctc tatcctgagt
    26821 ataaacgcca tggtttgggg cctttgacca agcgttttgg tgtggccttg gaacatcacc
    26881 acatggccaa ctacgatgcg gaagcgactg gtcgtctgct tttcatcttt atcaaagagg
    26941 tagcagaaaa acatggtgtg accgatttag atagactcaa cattgatcta atcagtccag
    27001 attcttacaa aaaagctcgg atcaagcatg cgaccatcta tgtcaagaat caggtaggtc
    27061 taaaaaatat ctttaagctg gtttccttgt ctaataccaa gtattttgaa ggagtgccac
    27121 ggattccgag aacggttcta gatgcccatc gagagggctt gattttaggt tcagcctgtt
    27181 cagagggtga agtttttgac gtggtcgttt ctcaaggtgt ggatgcggcg gttgaggtgg
    27241 ccaagtatta tgactttatc gaggtcatgc caccggctat ctatgcgccc ttgattgcca
    27301 aagagcaggt caaggatatg gaggaactcc agaccattat caagagtttg atagaggttg
    27361 gagatcgcct tggcaagcct gttctggcta cgggaaatgt tcactatatc gaaccggaag
    27421 aagagattta tcgtgaaatt atcgtccgta gtttgggaca gggtgcgatg attaaccgaa
    27481 ctatcggtca tggtgaacat gcccaaccag cgccacttcc aaaggctcat tttcgaacga
    27541 ctaatgagat gttggatgaa tttgcctttt tgggagagga actggctcgt aaactggtta
    27601 ttgaaaacac caatgccttg gcagaaatat ttgaacccgt tgaagtcgtt aagggtgact
    27661 tgtatacgcc tttcatcgac aaggctgaag aaacagttgc tgagttgacc tataagaaag
    27721 cttttgagat ttatgggaat ccgctgccag atattgttga tttgcggatt gaaaaagaat
    27781 taacatccat actggggaat ggatttgctg tgatttatct ggcatcgcag atgctggtgc
    27841 aacgttctaa tgaacggggt tatttggttg gttctcgtgg gtctgtcgga tctagtttcg
    27901 ttgcgaccat gattgggatt acggaggtca atcctctctc tcctcactat gtctgtggtc
    27961 agtgtcagta cagtgagttt atcacagatg gttcgtacgg ttcaggattt gatatgcccc
    28021 ataaggactg tccaaactgt ggtcacaaac tcagtaaaaa cggacaggat attccgtttg
    28081 agaccttcct tggttttgat ggggataagg ttcctgatat tgacttgaac ttctcgggag
    28141 aagatcagcc tagcgcccac ttggatgtgc gtgatatctt tggtgaagaa tatgccttcc
    28201 gtgcgggaac ggttggtacg gtagctgcca agactgccta tggatttgtc aagggttacg
    28261 agcgagatta tggcaagttt tatcgtgatg cagaggtgga acgcctcgct caaggagcgg
    28321 cgggtgtcaa gcggacaaca ggccaacacc cggggggaat cgttgttatt ccgaactaca
    28381 tggatgtcta cgattttacg cctgtccagt atccagcaga tgatgtcacg gctgaatggc
    28441 agaccactca ctttaacttc cacgatatcg atgagaacgt cctcaaactc gatgtactgg
    28501 gacatgatga tccgaccatg attcgaaaac ttcaggattt gtctggtatt gaccctaatg
    28561 aaattcctat ggatgacgaa ggcgtgatgg cactcttttc tgggactgat gtgctagggg
    28621 taacacctga acaaattgga acgcctacgg gtatgttggg gattccagag tttggaacaa
    28681 atttcgtacg tggaatggta gacgaaaccc atccgacaac ctttgcggaa ttgcttcagc
    28741 tgtctggtct gtcacacggt actgacgttt ggttggggaa tgctcaggat ctgattaagc
    28801 aaggaatagc ggacctatcg actgttatcg gttgtcggga cgacatcatg gtttacctca
    28861 tgcatgcggg tctggaacct aagatggcct ttaccattat ggaacgggta cgtaagggtt
    28921 tgtggctaaa gatttcagaa gaggagagaa atgactatat cgaagccatg aaggctaata
    28981 aggtgccaga gtggtatatc gaatcctgtg ggaaaattaa gtacatgttc cctaaggccc
    29041 atgcggcagc ctacgttatg atggccttgc gtgtagctta cttcaaggtt caccatccta
    29101 tttattacta ctgtgcttac ttctccattc gtgctaaggc ttttgatatc aagaccatgg
    29161 gtgcgggctt ggaggtcatc aagcgcagaa tggaagaaat ctctgaaaaa cggaagaaca
    29221 atgaagcctc taatgtggaa atcgatctct atacaactct tgagattgtc aatgaaatgt
    29281 gggaacgagg tttcaagttt gggaaattag atctctactg tagtcaggcg acagagttcc
    29341 tcatcgacgg ggataccctt atcccaccat ttgtagcaat ggatggtctg ggagagaacg
    29401 ttgccaagca actggtgcgg gcgcgtgaag agggagaatt cctctctaaa acagaactac
    29461 gcaagcgtgg tggactctca tcaaccttgg ttgaaaagat ggatgagatg ggtattcttg
    29521 gaaatatgcc agaggataac cagttgagtt tgtttgatga gttgttttaa aaaattgctt
    29581 aataatctat taaaagaggc taacgtatat ccaatagatt tacattagct ttcttttttg
    29641 ttaaaatagt ctatggaaag agggtgagag tatgtcaaag atgagtataa gcatccgtct
    29701 ggatagtgag gttaaggagc aggcccaaca ggtgtttagt aatctgggaa tggatatgac
    29761 aacagctatt aatattttcc ttcgtcaggc aattcaatat cagggattac cttttgatgt
    29821 tagactagac gaaaatcgga agttgctcca agtgttaacg gatttagacc aaaatcgtaa
    29881 tatgagccag tcttttgaat cagtctcaga tttgatggag gacttacgtg cttaagattc
    29941 gttatcataa acagtttaaa aaagatttta agttggctat gaagcgtggt ttgaaggcag
    30001 aattattaga agaagttttg aattttctgg ttcaagaaaa agaacatcct gccagatatc
    30061 gtgatcattc attgacggca tccaagcatt ttcaaggagt tcgtgaatgc catacccagc
    30121 cagattggct tttggtttat aaagtagaca agtcggaatt gattttaaat ttgctgagga
    30181 caggcagtca cagtgattta ttttaatcta ttttaagggg gttctcatga aactaagaat
    30241 atttgcggaa gataagccgg ctaagaaggt atttgaatat caattagaac ttgctgatcg
    30301 tacaattctt ctatcaacag cactcttgtc aggtgctatt gctttagcgg gattattctc
    30361 tgctttgaaa gaaaaataaa aatagaaaag agaaaattac atggttttac caaattttaa
    30421 agaaaatcta gaaaaatatg cgaaattatt ggttgcgaat ggaatcaatg tgcaacctgg
    30481 tcacactttg gctctctcta ttgatgtgga gcaacgtgaa ttggcacatc taatcgtgaa
    30541 agaagcttat gccttgggtg cgcatgaggt catcgttcag tggacagatg atgtgattaa
    30601 ccgtgagaaa ttcttccatg ccccgatgga gcgtttggac aatgtgccag aatacaagat
    30661 tgctgagatg aactatctct tggagaacaa ggctagccgt cttggagttc gttcatctga
    30721 tccaggtgcc ttgaacggag tggacgctga caagctttca gcttctgcta aagctatggg
    30781 acttgccatg aagccaatgc gaatcgcaac tcaatctaac aaggttagct ggactgtagc
    30841 agccgctgct ggacttgagt gggctaagaa agtcttccca aatgctgcga gcgacgaaga
    30901 agcagtcgat ctcctttggg accaaatctt caaaacttgc cgtgtctacg aagcagatcc
    30961 tgttaaggcc tgggaagagc atgcagccat tctcaagagc aaggccgata tgcttaataa
    31021 ggagcaattt tcagcccttc actacacagc gccaggaaca gatttaacac ttggtttgcc
    31081 aaagaaccac gtttgggaat cagctggtgc tgtcaatgca cagggcgaag gattcttgcc
    31141 aaatatgccg acagaagagg tcttcacagc gcctgacttc cgtcgtgcag atggttatgt
    31201 cacttctaca aaaccgctta gctacaacgg aaatatcatt gaaggcatta aggtgatctt
    31261 taaggatgga caaatcgtag atatcactgc tgagaagggt gatcaggtta tgaaagacct
    31321 tgtctttgaa aatgcgggtg cgcgtgcctt gggtgaatgt gccttggtac cagatccaag
    31381 tccaatttct cagtcaggca ttaccttctt taacaccctt ttcgatgaaa atgcgtcaaa
    31441 ccacttggct atcggtgcag cctatgcgac tagcgttgtt gatggagcgg agatgagcga
    31501 agaggagctt gaagctgcag ggcttaaccg ttcagatgtt cacgtagact ttatgattgg
    31561 ttctaaccaa atggatatcg atggtattcg tgaggatgga acgcgggtac ctcttttccg
    31621 taatgggaat tgggcaaatt aaggagataa tatgttagga agtatgttcg ttggtctcct
    31681 agtgggattt ttagcaggtg ctatgaccaa tcgtggagag cgaatgggat gttttggaaa
    31741 aatgtttctc ggttggatcg gagcctttct aggtcacttg ctctttggaa cttgggggcc
    31801 agttttatca ggaacagcta ttatcccagc tgttttaggt gccatgattg tcttagctat
    31861 tttttggaga cgaggaagtt aatttcctaa atctgatact caatgaaaat caaagagcaa
    31921 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgcaga tagaactgac
    31981 gaagtcagta acatatatac ggcaaggcga cgttgacgcg gtttgaagag tatgaaacga
    32041 aaaggaggtt ggtcattgta ccagcctcct tttgatatga tataa
//
LOCUS       DBEJJE010000024        31956 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEJJE010000024 DBEJJE010000000
VERSION     DBEJJE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.24"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL3F5_001080"
     CDS             <1..333
                     /locus_tag="ACL3F5_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0514904.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL3F5_001081"
     CDS             500..1198
                     /locus_tag="ACL3F5_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0514905.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL3F5_001082"
     CDS             1195..2247
                     /locus_tag="ACL3F5_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0514906.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3F5_001083"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3F5_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0514907.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3238..3393
                     /locus_tag="ACL3F5_001084"
                     /pseudo
     CDS             3238..3393
                     /locus_tag="ACL3F5_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            3819..4040
                     /locus_tag="ACL3F5_001085"
     CDS             3819..4040
                     /locus_tag="ACL3F5_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514908.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKIDNLKEVITKLKANA"
     gene            4359..5288
                     /locus_tag="ACL3F5_001086"
     CDS             4359..5288
                     /locus_tag="ACL3F5_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514909.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5302..6225
                     /locus_tag="ACL3F5_001087"
     CDS             5302..6225
                     /locus_tag="ACL3F5_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0514910.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6483..7958
                     /locus_tag="ACL3F5_001088"
     CDS             6483..7958
                     /locus_tag="ACL3F5_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0514911.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8230..9216
                     /locus_tag="ACL3F5_001089"
     CDS             8230..9216
                     /locus_tag="ACL3F5_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0514912.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9338..10198
                     /locus_tag="ACL3F5_001090"
     CDS             9338..10198
                     /locus_tag="ACL3F5_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0514913.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWLIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(10376..11440)
                     /locus_tag="ACL3F5_001091"
     CDS             complement(10376..11440)
                     /locus_tag="ACL3F5_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0514914.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEERITDLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEDSEARTKIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPYQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11503..12414)
                     /locus_tag="ACL3F5_001092"
     CDS             complement(11503..12414)
                     /locus_tag="ACL3F5_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0514915.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12407..13000)
                     /locus_tag="ACL3F5_001093"
     CDS             complement(12407..13000)
                     /locus_tag="ACL3F5_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0514916.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(12987..13313)
                     /locus_tag="ACL3F5_001094"
     CDS             complement(12987..13313)
                     /locus_tag="ACL3F5_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0514917.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13452..14618)
                     /locus_tag="ACL3F5_001095"
     CDS             complement(13452..14618)
                     /locus_tag="ACL3F5_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0514918.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVIGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14676..15833
                     /locus_tag="ACL3F5_001096"
     CDS             14676..15833
                     /locus_tag="ACL3F5_001096"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0514919.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            15875..17725
                     /locus_tag="ACL3F5_001097"
     CDS             15875..17725
                     /locus_tag="ACL3F5_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0514920.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18028..18660)
                     /locus_tag="ACL3F5_001098"
     CDS             complement(18028..18660)
                     /locus_tag="ACL3F5_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0514921.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18682..19554)
                     /gene="sdaAA"
                     /locus_tag="ACL3F5_001099"
     CDS             complement(18682..19554)
                     /gene="sdaAA"
                     /locus_tag="ACL3F5_001099"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0514922.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19563..20234)
                     /gene="sdaAB"
                     /locus_tag="ACL3F5_001100"
     CDS             complement(19563..20234)
                     /gene="sdaAB"
                     /locus_tag="ACL3F5_001100"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0514923.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20476..21063
                     /locus_tag="ACL3F5_001101"
     CDS             20476..21063
                     /locus_tag="ACL3F5_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0514924.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21115..21441)
                     /locus_tag="ACL3F5_001102"
                     /pseudo
     CDS             complement(21115..21441)
                     /locus_tag="ACL3F5_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            22192..22560
                     /locus_tag="ACL3F5_001103"
     CDS             22192..22560
                     /locus_tag="ACL3F5_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HGR0514925.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGADW
                     IFTNIIDGWDGRRDNQLRIG"
     gene            22568..22780
                     /locus_tag="ACL3F5_001104"
     CDS             22568..22780
                     /locus_tag="ACL3F5_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514926.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            23154..23279
                     /locus_tag="ACL3F5_001105"
     CDS             23154..23279
                     /locus_tag="ACL3F5_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514927.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            23260..23505
                     /locus_tag="ACL3F5_001106"
     CDS             23260..23505
                     /locus_tag="ACL3F5_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514928.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            23662..24720
                     /locus_tag="ACL3F5_001107"
     CDS             23662..24720
                     /locus_tag="ACL3F5_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514929.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            25035..26012
                     /locus_tag="ACL3F5_001108"
     CDS             25035..26012
                     /locus_tag="ACL3F5_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514930.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            26389..26763
                     /locus_tag="ACL3F5_001109"
     CDS             26389..26763
                     /locus_tag="ACL3F5_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR0514931.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            26770..26952
                     /locus_tag="ACL3F5_001110"
     CDS             26770..26952
                     /locus_tag="ACL3F5_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514932.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            26971..27873
                     /locus_tag="ACL3F5_001111"
     CDS             26971..27873
                     /locus_tag="ACL3F5_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514933.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            27929..28261
                     /locus_tag="ACL3F5_001112"
     CDS             27929..28261
                     /locus_tag="ACL3F5_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0514934.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            28258..28986
                     /locus_tag="ACL3F5_001113"
     CDS             28258..28986
                     /locus_tag="ACL3F5_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514935.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            29465..29662
                     /locus_tag="ACL3F5_001114"
     CDS             29465..29662
                     /locus_tag="ACL3F5_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514936.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLALLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            30119..30358
                     /locus_tag="ACL3F5_001115"
     CDS             30119..30358
                     /locus_tag="ACL3F5_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514937.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            30911..>31956
                     /locus_tag="ACL3F5_001116"
     CDS             30911..>31956
                     /locus_tag="ACL3F5_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGR0514938.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPAPKPAPAP"
BASE COUNT        10009 a         5382 c         6570 g         9995 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctag ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag acccctatca cttcgattca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgt ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaagttg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgttg taatatttta
     3061 ttaaataaga taggctttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgtttag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atcttttatg
     3241 gcatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac aggtagtata
     3301 acagaagcat cacacgtttt tcaaatctca cgtaatacca tttatggctg gttaaagcta
     3361 aaagagaaaa caggagagct aaaccaccaa gtatagtgta ttgaatctat aacagtacac
     3421 cttggctgct aaaatatttc tataaattaa tttgactttc ctgatagagt tgttcacatc
     3481 ttatttcaaa ctactataaa agttctataa tctctttata agatttgccc atcagacgaa
     3541 atataatgga ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcga
     3601 tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt ttactataga acgatttgaa
     3661 ggcgtttatg atatttagct gtatgagagt cttttaaaag tgttttgatg gtttggattt
     3721 cttctttagt tgatttcata tcactgttat ataatgcttt ttgatttgag tctagtatta
     3781 gtaagcagac tcaaacctta gaaaatcttt tgagatcatt gacaggtgta tcgaatccta
     3841 ccacagattc agcacctctg gttttggcag aggctaagaa agcttttgca gatgatagtt
     3901 tgatagagca aggtttacgt gatatcttgc aaacagtcaa agatgccatt gcttccctag
     3961 agtccattaa ggaaagccag tcagcaacta agattgataa tcttaaagag gttattacta
     4021 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatcgctgag
     4081 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atacttataa cagagtgacg
     4141 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     4201 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     4261 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     4321 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     4381 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg ggcactctgg ttgattctat
     4441 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     4501 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     4561 tatttagttc aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct
     4621 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     4681 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     4741 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     4801 tattggaaag tcttggtctc aaagaagtca atttttacgc tgacctgggc atctggccct
     4861 atctcctact tttcctaggt atttggaaag gctttggata tagcagtgtc atgtactatg
     4921 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     4981 agtggcaacg tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga
     5041 ccatccttgc agtcggaaat atcttccgcg cagacttcgg tctcttctat caaatcccac
     5101 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtc tttaatggtt
     5161 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     5221 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     5281 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     5341 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     5401 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     5461 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     5521 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     5581 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     5641 cggacaacct ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc
     5701 aacgctggtt tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact
     5761 gtttgggcct tgattgtgcc aatgcttctc tcccccttta acatcatctt gatgcgttcc
     5821 ttcttcaaga agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt
     5881 gaggcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     5941 acgcttttga cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     6001 agtgataact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     6061 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     6121 cgtatggcca tggttgtggt tgcaaccctt ccaatcgcga ttttatatcc attcttccaa
     6181 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgaaaaag
     6241 aacatttctc agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc
     6301 aaaccgcgtc aacgtcgcct tgccgtagat atatgtaact gacttcgtca gtcttatcta
     6361 caacctcaaa gcagtgcttt gagcagcctg cggctagttt tctagtttgc tctttgattt
     6421 tcattgagta taagatcatt acattgttta taagtttaaa aataaaaaaa ggagttttta
     6481 tcatgaaaaa ctggaaaaaa tatgcttttg catctgctag tgtagtcgct ttggctgcag
     6541 gtcttgctgc ttgtggcaac ttgacaggta acagtaaaaa agctgctgat tcaggtgaca
     6601 aacctgttat caaaatgtac caaatcggtg acaaaccaga caacttggat gaattgttag
     6661 caaatgccaa caaaatcatt gaagaaaaag ttggtgccaa attggatatc caataccttg
     6721 gctggggtga ctatggtaag aaaatgtcag ttatcacatc atctggtgaa aactatgata
     6781 tcgcctttgc agataactat attgtaaatg ctcaaaaagg tgcttatgct gacttgacag
     6841 aattgtacaa aaaagaaggt aaagaccttt acaaggcact tgatccagct tatatcaagg
     6901 gtaatactgt aaatggtaag atttacgctg taccagttgc agccaacgta gcatcatctc
     6961 aaaactttgc cttcaacgga actctccttg ccaaatatgg tatcgatatt tcaggtgtta
     7021 cttcttacga aactcttgag ccagtcttga aacaaatcaa agaaaaagct ccagacgtag
     7081 taccatttgc tattggtaaa gttttcatcc catctgataa ctttgactac ccagtagcaa
     7141 acgggcttcc attcgttatt gaccttgaag gcgatactac taaagttgta aaccgttacg
     7201 aagtgcctcg tttcaaagaa cacttgaaga ctcttcacaa attctatgaa gctggctaca
     7261 ttccaaaaga cgtcgcaaca agtgacactt catttgacct tcaacaagat acttggttcg
     7321 ttcgtgaaga aacagtagga ccagctgact acggtaacag cttgctttca cgtgttgcca
     7381 acaaagatat ccaaatcaaa ccaattacta acttcatcaa gaaaaaccaa acaacacaag
     7441 ttgctaactt tgtcatctca aacaactcta agaacaaaga aaaatcaatg gaaatcttga
     7501 acctcttgaa tacgaaccca gaactcttga acggtcttgt ttacggtcca gaaggcaaga
     7561 actgggaaaa aattgaaggt aaagaaaacc gtgttcgcgt tcttgatggc tacaaaggaa
     7621 acactcacat gggtggatgg aacactggta acaactggat cctttacatc aacgaaaacg
     7681 ttacagacca acaaatcgaa aattctaaga aagaattggc agaagctaaa gaatctccag
     7741 cgcttggatt tatcttcaat actgacaatg tgaaatctga aatctcagct attgctaaca
     7801 caatgcaaca atttgataca gctatcaaca ctggtactgt agacccagat aaagcgattc
     7861 cagaattgat ggaaaaattg aaatctgaag gtgcctacga aaaagtattg aacgaaatgc
     7921 aaaaacaata cgatgaattc ttgaaaaaca aaaaataatc agctaaattg atttcgtgta
     7981 ttcattccta actcctaaaa taagaatcac tgctttcctc aggttggtct ggggagggca
     8041 gtggtttttt tggcacaagg atatagatat ccatgttttc tcttgtcctt attttaacca
     8101 ttcaggaaat ttcgagaacc ctctacaatt tccagtcaaa taaattgcat tcgttttttc
     8161 aagcaggtat actagtatag ataaataaaa aatttagaaa atttaagaat agaaaagaga
     8221 acaaatctta tggcaaaaga tattcgtgtc ttactttact acctttatac tccaattgaa
     8281 aacgcagagc aatttgctgc agaccacttg gctttctgta aatcaatcgg ccttaaaggc
     8341 cgtatcctag tcgctgacga gggaattaac ggaacagttt caggtgacta tgaaacaact
     8401 caaaaataca tggactacgt tcacagcctt ccaggaatgg aagatctctg gttcaagatt
     8461 gacgaagaaa atgaacaagc cttcaagaag atgtttgttc gctacaagaa agaaattgtc
     8521 caccttggtt tggaagacaa cgactttgac aatgacatca acccacttga aacaacaggt
     8581 gcttacttgt ctccaaaaga gttcaaagaa gcgcttcttg ataaagatac cgttgtcctt
     8641 gacacacgta acgattatga gtacgaccta ggacatttcc gtggggctat tcgcccagat
     8701 attcgcaact tccgtgagtt accacaatgg gtccgtgaca acaaagaaaa attcatggac
     8761 aagcgtgtcg tggtttactg tacaggtggt gttcgctgtg agaaattctc aggctggatg
     8821 gttcgtgaag gttacaaaga tgttggccaa ttgcacggag gaatcgcaac ttacggtaaa
     8881 gacccagaag ttcaaggtga gctttgggat gggaaaatgt acgtctttga cgagcgtatt
     8941 gccgttgatg tcaaccatgt caacccaact atcgtaggga aagactggtt tgatggaacg
     9001 ccatgtgaac gttatgtcaa ctgtggaaat cccttctgta accgtcgtat cttgacatca
     9061 gaagaaaatg aagacaagta ccttcgtgga tgctcacacg agtgccgtgt tcacccacgt
     9121 aaccgctatg tttcaaaaaa tgaattgaca caagctgaag tgatcgagcg cctagccgct
     9181 atcggtgaaa gcttggatca agcagctact gtataagatc aaacagtcct caggggctgt
     9241 ttttctatgc tttgtactca aaaatctaaa gtttgtttct gtatctttca gaaaaataag
     9301 gtatactgtg tgtaagcgat ttcaaaggag tccagttatg gcgaaaacat tttttattcc
     9361 aaataaacag agcattttag gagaacaaga gattttgaat gccaagtcga tcttggcctt
     9421 gctagacggt ttggagtcac atagctatga tgtagtctat ctccgtcagc ctcttaatcg
     9481 tctcgaatat attgagtgtg cgatagtggg gcaatcacaa tttcttttta aggtcagtta
     9541 tgctgatggt caaaaggctt accgtgtcga tcttcctgac ctactaacaa agacagactg
     9601 gctgattatc aagtcatttt tagatgcttt gcttgcttat acagggactg atattgaagg
     9661 gctagatggt tttgattttg aagcttattt ccaagcaagt attcaagcct atctagcaga
     9721 ccctgtagct cgttttacga tttgccaagg aatttttaat cctattttct ttagtcgtga
     9781 gaacttgaaa agctttttag aggcagatgg cttggctcag tttgaagcgc gtgtgcgtgc
     9841 ggttcaagag acagatgcct actttgcgag agtttccttc tatcaggatg gagaaggaaa
     9901 agtgcatggc gtttaccatc tagctcaagg agtcaagaca gttttaccga gagaaccgtt
     9961 tgttcctgca gcctatattg agcaattggt ggataaggaa gtccagtggg agattgactt
    10021 ggttcaaatc acaggagacg gctctaaacc agaagactat gaagccattg cccgcttgga
    10081 ctatgcaaaa ttcttagagg tattaccccc atctttttac caccagctag acgccaatca
    10141 aatagaaata caacccatcc taggacaaga ttttaaaaca ttagcacaag aaaagtaaag
    10201 cagaagcagg tcaatcgact tgcttttttg acatagaaaa aatcctgcca aggatgacag
    10261 gattgctact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgtacttga
    10321 gtacggtaag gcgaagctga cgtggtttga atttgatttt cgaagagtat gaagtttaaa
    10381 gaaaggccaa gatacgaaga taatctccaa tcagtgccac ttcagctaca aagaagagga
    10441 ggataataac tccgttcaca aggacagaca agaataattg atagaaggag tcggtttcac
    10501 ttgcttgact tggtcttgta atgatatgga gactggcaag cagaatgatt ccaatgctaa
    10561 ttacacacaa gagagctgta aatcgtaggc tatcaaagaa agcaaagaaa ctagcaatag
    10621 cagtgaggaa gattggaatt gccaagagtt gactatattg ttggagaacc ttgtctagcg
    10681 tccagtcctt ttcctggtgg ataaatcgtc tcacaacgaa actacccaag aggaatgaaa
    10741 agaagaagag tgttgtcgct actaggatag agatgataga aaaaagagtt aaaggagcta
    10801 gctgctcagg gaagcgactg ttaatgcttg ctatatgtcc atagtaagca tgtttgatgt
    10861 gatagatact aaagaaaaag gaagatgcag aaaacagaat gagcaagaga aaggctgtgt
    10921 aactgtgtgt gatacttgtt tccaacttac ttgtaggaga tttgatcgct tccactagcc
    10981 aagaccaaaa atcaagcact tgctctttcc atttatccct agattttgga gcttggtagg
    11041 ggatataagg actttctaaa gatttactga taagaagtgg ctctttcgta gttgcttttt
    11101 gctgaggaag agcttcttgg ctctcttcag ctatagtgac tttttctgtt tctttagaaa
    11161 ggtctggctc ttcttcagta gaattagatg ccttcttttc ttctattttt gttctcgctt
    11221 cactgtcttc aggagtttca attttctctt cttgctggct ttccaattcg acttcagctt
    11281 gagagacttc ctcctctaac tgagtatttt tttcaattgg tgtatcgagg tcggttatcc
    11341 tttcttcagc cttgtctgca acctcttgag cttgctcttc aggcttgttc ttgcttgttg
    11401 tttttacaaa atcattactt tcaaaccatt cttgtttcat ggtagaacct cctttttagt
    11461 tagataaata tgcttccata gtagcagatg taagcgtttt tgtcaacgtc tgcttggtgt
    11521 ggatattaga tcaatattat catcagatct cgcaatgagt tgatccttga catcggtttt
    11581 ttcagttttg taagggttgc ttaattccgt acctcttgat tcaggctttt ctcttgtgaa
    11641 ttggaagata gaaccatagt tgcttgagat gtcccagtta attcgttggt tttctttctg
    11701 gtctaggatg attctgagat aatctttggc agtcagttca accttaccat ggacttggat
    11761 attttcagcg tggaagtgat tatctgttga ctctagctga ctatctgtaa gaactgtatc
    11821 aaagatatta acgatattgg gcgttgtgag tttactgttt ttgatacgac ttccttcaat
    11881 tcggaggata tagctgtttg tattgagggt cgcattttca aggctagcat ttatgatggt
    11941 ggtttgtccg cgattggctg agatgttgat cccttttaga gttctccctt ttggtagtcg
    12001 gagaataact tcttcaaaac gactagagta gctacttgcg atatgaagaa tcccaccaat
    12061 tccagaagag agaaacggag tttcagacag tttcttatca gtgagactca gagttctatc
    12121 gttctgattg gtgataagat catggtgagc agaaagagat ggatggtaag aaatgtggat
    12181 ttgatcatcg aaagagtctg tgatggtgag cgtgtgttgg tggagagtaa tttctaggtt
    12241 ttcgacttcc ttgccaaagg ttagcttttc cgtacggcta tcatagacag gttctttgga
    12301 catggaaagt aggctcttaa tcccgtcaga ttggatacct acaaaaagca ggataaagcc
    12361 gataacggta gtcaccacac caaagatgag aaatcctttt gtccatttac gcatgctggt
    12421 tacctctctt tcttttttta agaacaaatt gtaccaggcg aacaatgagt agaccgaaga
    12481 agcgagctac ataggaaatg cctagtaaaa ctagcgaaga agcaccgata gccagtaaac
    12541 cagaaccaaa aatcaagata aaggctgatt tggcttgggc gaggacagtg aaactttcaa
    12601 ctaaaaatag gaatccgccg atgataccca gtatggaaac tgcaaagaaa gccagaatga
    12661 cagtcaaagc ggctacaagg attgcgaaca gggtcacgag gatggcgatt cccagaggaa
    12721 tgccgatagg tgctgcaagg agggctaaca aggcgatatg taaaatttgt cggttatttt
    12781 tttgagcggg tgcttcattg atttttttat cgagaagatt ggatagaact tcgtgggccg
    12841 cttctttggg agttcccaaa ctagcgatga gttcttcttc tccttcgact ccagcatcgt
    12901 caaagagctc tctgaaatag tccatggctt cgatacggtc agcttcaggt agtttcttga
    12961 gatagagttc tagctgagtc aggtattcag ttcttgtcat ggcggatact cccttctatg
    13021 atgccattga tggtgtctgt atagagtgtc cattcatctt ttagggtcaa gagctgctct
    13081 ataccaccgt ttgtcaagga gtagtatttg cgcatgcgac cttggaactc tctagaatag
    13141 gttgtcagaa agctattgcc ttccaatttt ttgagaatgg gatagagtgt ggattctttg
    13201 atattagcga tcagcttaat ggtttggcta atctcataac cataagaatc accctgctcc
    13261 agtacagcca agatgagaaa ttcaatcaag gcagaggatg ttggaaagta catgggaaac
    13321 ctccttttct aatgtgtaag atttttatat ataatttttc tacacataca ttgtacatct
    13381 aaaagaaagc cctgtcaaga gaaatgtgta aaatttttat atataaaaaa cttctagcta
    13441 aaactagaag tttaaaggat cttatccgct ctgtccactg taaagagggc cacagtcatc
    13501 aggatatcga tgagcaagag ggcagctaca gctggtaccc aagagtggaa caggtcaaaa
    13561 ctgtaaccaa agagggttgg cccaaaggct gctaggatat agcctcctgt ttgagatagg
    13621 ccggacaatt gggctgtctt ttcaggggcg cttgtcttga gtgaaaagtt gaccatgaga
    13681 taagggaaga gggcgctggt tgcggttccg atgaggagat ggatggcaag ccagtaaatg
    13741 aaattattga ttgggaaaaa gagcatggaa atgccgatca caccagctag tgaaaccaga
    13801 gtgagcatga gctgacggtt gcgagtagat aaactggttg tcaggcttgg gatggtcatt
    13861 gaaaaaggaa tgctaatcag agataagata gaagtcagca agccagcttc gtgactggat
    13921 agacctgcat ggatagacat ggtaggtaac caggtcatga cggtgtaaaa gatcaaggat
    13981 tgaaaacctg aaaagataat aattgcccaa acctgtttat tacgcatgac ctttatttga
    14041 cttttttgtt tggtttgtgg agctagtcta tgattatagc ggtgatttgg gagccagacc
    14101 aaaaaagttg ctagacagag taacgtgagg agaaggataa gtcctttcca agaactggct
    14161 tgtgtaatgg gcacagctag ataggaagcc agagccgttg caatccccat agacgttaca
    14221 tataaggtgg tcagaaaacc aattttcttt ggttgattgg cttggataag actaggaagc
    14281 aggacattga tgactgcgac acttgcccca accatcaagg ttcctagata gagtaggggc
    14341 agattgatta gtcgaataag tgagccgatg gtcaagaaga agaggctgta ggtgaagaga
    14401 tgctccaagc cgattttctg agccagttgg gtagaaaatg gtgaaaagag ggtaaacata
    14461 aggagaggca ggctggtcaa gacaccaagc gaactaactt ctacctccag accttgcgaa
    14521 atatttccca aaataatggg taaaacagta aaaggagttc gcaaggaaac accaatcagg
    14581 ataatacctg gaacaaaaaa gagtgattgc tttttcatat aatacctctt atagctgatt
    14641 ttaataacag cttattttaa ggctttttca ctataatgtc aagtaaggtt tctggctttc
    14701 aagataaaaa tgggaaagtc ttgaaaatta tgatagaatg gtggaaggaa aaattcagga
    14761 gagtagtagt gactcaaaat gttgaaagtc ttctcgtatc cattgtaatc agtgcataca
    14821 atgaagaaaa atatctgcct ggtctaattg aagacttaaa aaatcaaacc tatcctaaag
    14881 agaatattga aattctattt ataaatgcta tgtccacaga tgggaccaca gctatcattc
    14941 agcaatttat aaaggaagat acagagttta actcaattag attgtataac aatcctaaga
    15001 aaaatcaagc tagtggtttt aacctgggag ttaaacattc tgtaggggac cttattttaa
    15061 aaattgatgc tcattcaaaa gttactgaga gttttgtaat gaacaatgtg gctattattc
    15121 aacaaggtga atttgtctgt ggggggccta gaccgacgat tgtcgaagga aaaggaaaat
    15181 gggcagagac cttgcatctt gttgaggaaa atatgtttgg cagtagcatt gccaattatc
    15241 gaaatagttc tgaggataga tatgtttctt ctatttttca tgggatgtat aaacgagagg
    15301 ttttccagaa ggttggttta gtaaatgagc aacttggccg aactgaagat aatgatattc
    15361 attatagaat tcgagaacat ggttataaaa ttcgctatag cccaagtatt ctatcttatc
    15421 agtatattcg accaacattc aagaaaatgc tgcatcaaaa gtattcaaat ggtttgtgga
    15481 ttggcttgac aagtcatgtt cagtttaagt gtttatcatt atttcactat gttccttgtt
    15541 tatttgtttt gagtcttgtg tttagtctag cattgttacc gatcacattc gtattcataa
    15601 ctttactatt aggtgcctat tttctacttt tgtcactact cactttgctg actttattaa
    15661 aacataaaaa tggatttcta attgtgatgc cctttctttt attttccatt cactttgctt
    15721 atggctttgg gacgattgta ggtttaatta gaggatttaa atggaagaag gagtacaagg
    15781 gaacaataat ttatttggat aaaataagcc aaataaatca aaatatgcta taataacaat
    15841 atagtaaaac tcttttaagg aggagtagat ttctatgaat aaaaaactaa cagattatgt
    15901 gattgatctg gtggaaattt taaataaaca acaaaagcag gttttctggg gaatatttga
    15961 tattttcagt atggtggttt ccataattgt atcttatatt ttattttatg ggctgattaa
    16021 tccagcacct gttgactaca ttatctatac gagtttggcc ttcttgttct atcaattgat
    16081 gattggtttt tgggggttga acgcgagcat tagtcgttac agcaagatta cggatttcat
    16141 gaaaatcttt tttggtgtga ctgctagcag tgtcttgtca tatagtatct gttatgcctt
    16201 cttgccactc ttctccatcc gtttcatcat tctctttatc ttgttgagta ccttcttgat
    16261 tttattgcca cggattactt ggcagttaat ctactccaga cgcaaaaaag gtagtggtga
    16321 tggagaacac cgtcggacct tcttgattgg tgccggtgat ggtggggctc tctttatgga
    16381 tagttaccaa catccaacca gtgaattaga actggtcggt attttggata aggattctaa
    16441 gaaaaagggt caaaaacttg gtggtattcc tgttttgggc tcttatgaca atctgcctga
    16501 attagccaaa cgccatcaaa tcgagcgtgt catcgttgcg attccgtcgc tggatccgtc
    16561 agaatatgag cgtatcttgc agatgtgtaa taagctgggt gtcaaatgtt acaagatgcc
    16621 taaggttgaa actgttgttc agggccttca ccaagcaggt actggcttcc aaaaaattga
    16681 tattacggac cttttgggtc gtcaggaaat ccgtcttgac gaatcgcgtc tgggtgcaga
    16741 actgacaggt aagaccatct tagtcacagg agctggaggt tcaatcggtt ctgaaatctg
    16801 tcgtcaagtt agtcgcttca atcctgaacg cattgtcttg ctcggtcatg gggaaaactc
    16861 aatctacctt gtttatcatg aattgattcg taagttccaa gggattgatt atgtacctgt
    16921 gattgcggac attcaagact atgatcgttt gttgcaagtc tttgagcagt acaaacctgc
    16981 tattgtttat catgcggcag cccacaagca tgttcctatg atggagcgca atccaaaaga
    17041 agccttcaaa aacaatatcc gtggaactta caatgttgct agagccgttg atgaagccaa
    17101 ggtgcctaag atggttatga tttcgacaga taaggcagtt aatccaccaa atgttatggg
    17161 agcaaccaag cgcgtggcgg agttgattgt cactggcttt aaccaacgta gccaatcaac
    17221 ctactgtgca gttcgttttg ggaatgttct tggtagccgt ggtagtgtca ttccagtctt
    17281 tgaacgtcag attgctgaag gtgggcctgt aacggtgaca gacttccgca tgacccgtta
    17341 ctttatgacc attccagaag ctagtcgtct ggttatccat gctggtgctt atgccaaaga
    17401 tggggaagtc tttatccttg atatgggcaa accagtcaag atttatgact tggccaagaa
    17461 gatggtgctt ctaagtggcc acactgagag tgaaattcca atcgttgaag ttggaatccg
    17521 cccaggtgaa aaactctacg aagaactctt ggtatcaacc gaactcgttg acaatcaagt
    17581 tatggataag attttcgttg gtaaggttaa tgtcatgcct ttagaatcca tcaatcaaaa
    17641 gattggagag ttccgcactc tcagtggaga tgagttgaag caagctatta tcgcctttgc
    17701 taatcaaaca acccacattg aataaaaaag aaaaacgcat attatcaagt taaacaacct
    17761 tggtaatatg cgttttatta tgtagagact tatactcttc gaaaatctct tcaaatcacg
    17821 tcaacgtcgc cttgccgtat atggttactg acttcgtcag ttccatctac aaccttaaaa
    17881 cagtgttttg agctgacttc gtcagttcca tctacaatct taaaacagtg ttttgagcag
    17941 cccgcagcta gtttcctagt ttgctctttg attttcattg agtattactt cattttcttc
    18001 tgaaatggag ttgttaccca gtctatgcta ttgaaaatac gccaaaactt ctaagggttt
    18061 gtgagcgata taatcaggtt gatagtttag tagatctgct tgctctccaa atccccaagt
    18121 gacggccaat ttctgaatac ctgtttctcg agctcccagc atatcaaact tggtatctcc
    18181 gatgatgatg gcttgttctg gtgctagttg atgtgtctgt aaggcttggt gaatgacatc
    18241 tgccttatgg ggtgcttcag ggctagaacc ataaatacca tcaaagaaat gatggatttc
    18301 caagtttttg gccatgtctt gagcagtaga tgtattcttt gtcgtggtga tgtagagtgg
    18361 ataactgctc gataactcct caagcaagtc tataatctga ggaaagagtt gagcttcata
    18421 gatgcctttt gccttatagt aagaacgata tatctgcatg gcttcagaaa tttggtcttt
    18481 ggacaggcag gtcgcaaaac tactttcgag aggtggtccc ataaaaccac gaatagtttt
    18541 ggcatcaggg ctaggcaccc ccagctcttt aaaggtatag gtaaaggcat tgtgaatccc
    18601 gatagaacta tcaacgaggg ttccatccaa atcgaaaaaa atcgctgtga tagaggtcat
    18661 ggtttctcct atttgataag cttattctcc gaaaatctct ttttggaggc gacgaccagt
    18721 aggggtggta gcgagtccac cttcagctgt ttcacgaaag gcagttggca tgcttgctcc
    18781 tacttggtac atggcatcga tcacttcatc cacagggatt ttagattcga tacctgccaa
    18841 ggccatgtct gctgcgatga aagcaaagct agctcccatg gcattacgtt tgacacaggg
    18901 aacttcgacc aaacctgcaa cagggtcaca gatgaggcct agcatatttt taatgacaaa
    18961 ggcaatagct tgactggcct gataaggtgt tccacctgca gccagagtca aggcggcagc
    19021 actcatagca gaggctgaac caacttcagc ttgacaccca ccctcagcac ctgagatgga
    19081 ggcattgttt gcgatgacta gtccaaaggc accagcagca aagaggaaat ccaattgttg
    19141 ctcgtggctg aggtctaatt tttcaatagc agcagtgaga acggatggca gacagccagc
    19201 acttccagcg gttggagtgg cacagaccaa gcccattttg gcattgtgtt cattgactgc
    19261 gatggcattt cgggcagccg agagaatcgt ataatctgac agagtttttc cgttttcgat
    19321 gtagtgatcc aatttggcag catctccacc tgtcaggcca ctacgagatt tattttcatt
    19381 gaggccaagt tggacagagg ctttcataac ttccagattg cgttccatga gaaggaagac
    19441 ttcttcacgt tcgcgaccgg tcaattcaaa ctctgttgta atcatgagtt ctgcgacatt
    19501 tccttgaaag tccagatctg cttgctcgac caattctttg atagaataaa acatgcttcc
    19561 tcctatttaa agaaattgac attgtggaga tgagggattt ttcgaatttc ttcgatagcc
    19621 tcatcacagt tgcgactgtc aacttcgata atcataatgg ctttttcacc agctttttca
    19681 cgagtgacat tcatctgggc gatattgata ccatagcggg aaagcgcctc tgtaacaagg
    19741 gcaatcatac ctggaatatc ttgatgaacg atgatgatag tcggtgtatt catattgaga
    19801 gagacggcaa aaccattgag ttcggttacc tgaatatttc ctccaccgat agaaatacca
    19861 gtcacgctga tggtcttgtg ggcattttta acagtaattt tagtggtgtt agggtgaggg
    19921 gcattgctgt ctttctgaat ggtccagaca atcttgatac cacgcttgtg ggcaatttcc
    19981 agactatttg gaatttcagg atcatctgta tccattccta aaatacctgc aacaagggct
    20041 aggtctgttc cgtgaccacg ataggtcttg gcaaatgagt taaaaagttg gaattcaact
    20101 tctgtcggag tatcatcaaa aatggaagag acaatcttcc caatacgaac agcaccagcg
    20161 gtatggctac tagatgggcc aatcataact ggtccgatga tatcaaagac agattgaaaa
    20221 cgaagtgatt tcatcagttt ccccttataa aaattcttat ctctattata tcaaagaatg
    20281 aggggcttgg ctttaattgt ggatgaaaac ctttctaata cctcaaatag cataaaaata
    20341 gtatctttta tgacaaaaaa caccttattt agggaaataa aaaataattt tgtaatattt
    20401 ctacataaaa gtgtcaagaa acggtaatat ttaaagggta tgatagaact atagaaagaa
    20461 ggagaatttt cgaatatgaa atcaataact aaaaagatta aagcaactct tgcaggagta
    20521 gctgccttgt ttgcagtatt tgctccatca tttgtatctg ctcaagaatc atcaacttac
    20581 actgttaaag aaggtgatac actttcagaa atcgctgaaa ctcacaacac aacagttgaa
    20641 aaattggcag aaaacaacca cattgataac attcatttga tttatgttga tcaagagttg
    20701 gttatcgatg gccctgtagc gcctgttgca acaccagcgc cagctactta tgcggcacca
    20761 gccgctcaag atgaaactgt ttcagctcca gtggcagaaa ctccagtagt aagtgaaaca
    20821 gttgtttcaa ctgtaagcgg atctgaagca gaagccaaag aatggatcgc tcaaaaagaa
    20881 tcaggtggta gctatacagc tacaaatgga cgttatatcg gacgttacca attaacagat
    20941 tcatacctga acggtgacta ctcagctgaa aaccaagaac gtgtagcaga tgcctacgtt
    21001 gcaggacgtt acggttcatg gacagctgct aaaaacttct ggcttaacaa tggctggtat
    21061 taagaactaa cgaacaaata atatgtaaag agtcgaggaa atccctcggc ttttttatct
    21121 ttccttcgct tggtaataga tctctacttc ttttttgaga tgagacagca tagaagtttc
    21181 ctcggtcagc tctaggagtg agaacccttt ttggataagt ttcgcattat ccctacaaat
    21241 cccaatgcgg acatagcaga tagccagcct atcgtagctt ttcttattct tggcgtcctt
    21301 cagtaaagtg tagcagattt gcttacacat gtttttatct tgattgtata gatagagtgt
    21361 ggaaaggttt aatagaattg tcattcgcaa gtcatataaa tgttgatagt ttttatagac
    21421 ttctaagcgt tgcaagattt tctcggatta ttgacaaata aacggacatt ctgatagacg
    21481 attgtcctag cggcttagtg taaactttac aaatttggct tgtaattttt ttataaaatt
    21541 cactttagtt acttgacagt tattatattt tcgctcataa tatagataaa aggatgggat
    21601 agagtttaaa aatttgaaag cgctatccat aatcataacg cataattttc tccttttcgt
    21661 gaaaaaagtt aacgtaattt tgaaatgagc ttaataagag gtactatgta ggtagaaaat
    21721 aaagatagga gaaaaagtat gaataaaaaa atattttgta ttctagtatg tattatatca
    21781 ttgattagtc tagctataat ctttccatgg ggctggtcga tataatgtaa gggagcttga
    21841 gttgttagtg gaggataaaa tgttaagagt aatagtagtt attcaatctt tagtaataat
    21901 actgcttgct gttgctttat tattatctcg gaaaaacttt gattcgttaa atgttgttct
    21961 tataatgatg atcgtatcac aattgttgtt attagtatat ttgataaaat cagggaatca
    22021 gtgattagct gttatttgaa ttaagtaaac tgttaagctt caagcagtaa ctggttttaa
    22081 atatttaaaa taagataaag gaaggaagtc taatttaggt aactaaacaa agcctgcgat
    22141 cacttgttag gaaaccatcc taagcatgct taataaaaaa ggagaaaata aatggaactt
    22201 gtattaccaa ataattatgt tgtgattgat gaagaagaga tgatgtacct tgatgggggg
    22261 gctatatata tacccaggtg ggcaattaca ggagccatta ctggtgcagc atatgcagca
    22321 ttagcagcag gaggtggagg ccttcaacta gttcttgcat cttatggatt acgctccgca
    22381 ctggtagctg ggattgttaa aggtttagga gtattaggaa ttcatattgg aaatgctttt
    22441 gcaaatactg ttattagaag tattgcatct gctggaattg gtgctggagc tgattggatt
    22501 tttaccaata ttattgatgg ctgggatggg cgacgtgata atcaattgag aataggttaa
    22561 taatcttatg ttgattgttt taatttcagt tattgttgca ttcctgtatc ataaaattac
    22621 agagtatgtc aacaacagga aaattgatat tgttattttt ctatcattgc tgatttctca
    22681 ttttatttgg aattactatt ttttaccaat tgaaatattg atagcaatca gtggagcaaa
    22741 tttattatta agttttttaa aaaaattaca gattaaataa tattattcca tatgacatat
    22801 caactaggtc attagatttt attgaagata taaattaaaa acgaggttgg gaaaaaactc
    22861 aatttgaaag tgagattgag taaatctttc tatctatata acgtatatca tcaatatttt
    22921 tgaacacctg ataatatgca cttttcttat tttaaagatt ttttgccttt cttcatttct
    22981 tgaatgaatt ggagagatga ctttatttag gtgtttgaca ttactataga taggatttag
    23041 cagtactaat atgaactcat attataggtg tagacttaaa ttttggaagc aagctaaagg
    23101 atatcttatc taggtaacta agtgctataa caagatatat tggtggagtt agtatggcaa
    23161 ctattactaa tgctcttaat attgcggcta ctgttgctga agtcttctca ttaggaggag
    23221 ccattgcata tggtttagat atcgtagacg gtaaatttga tgggtattta tgggcgtaaa
    23281 actatagcta tgaaacattt ttttgcagga attggtgaaa ttcatttttt gttattttta
    23341 ttatatctaa gcatgtctgc tagtccaatt attggactag tgattggata tactaaaata
    23401 aatctaataa attctattat tatagctctt ggtatgatat tggcattaat tttggtatta
    23461 tcaagagtgt atagaaaata tttttataga gacgatgatg actaaagttt ttatcaataa
    23521 tttgggctcc ttgtcaactg tagtgggttg aagaaaagct aacgtctggg gaaggggtta
    23581 aagctttgct ttatcaaata ttgacttaca gagttgctct attgtattga tgtattctta
    23641 gtaaataata tggtgttttg aatgaaagat gatcagaaat atttattagc gggactttat
    23701 tcgcttctag ttgcaatatt ttattttcca ttgattgagt ccaaggggat ttttgtaagt
    23761 atattgatgg cggttttact tttatattta atatacttca ttgcaacagt cattcatatt
    23821 gtgataatta agtttataag aaaaaaatct tttaagtatt tggttctata tccatttact
    23881 tatgatggga gttggagatt tcaacctata aacttactct actttccaga aatggtgaga
    23941 gatgtcattc cgattaattt agttcaagaa tattgccaag gacaacctta cggactgtta
    24001 aaaaagatgc tgaaaagaat tcgattgtca cgagagatat ctttactcct ggctaccatt
    24061 atcgtctatt tttttacgca tagaattcta cctctttcag tatttacgtt catattttct
    24121 tacatattgc tatttgtaca atcttatttg ggtggtaata ccgcttggat tggaaataga
    24181 agattaataa tagatgatga atttgaaaaa atcttgcttt caaaaagtta tgtaaaagaa
    24241 atatcatctg cacgatactc agaatacttg acatgtgaat acaaaaacct tacaccaatc
    24301 atattgatag ctatttttga aaatttgctt gactcctact tgcttcagaa tcagagtgag
    24361 gttgacttag atatttttta taaagtttta cctttgcttt ataaagaaaa atatactatg
    24421 ggattcaatt actttgtaag tttaaattat ttactatata aggttggatt tttgggaatc
    24481 atttacgata atgaagcatt aagagatttg tcaaaacaat atttaaacaa aaatatttcg
    24541 gaattacaag atggttcttt cgagggcggt atacaagatg ctgttgcctc taaacaaata
    24601 gtagttataa atgaatttat agcttgttta aattccagat gcgtgccatc ccaatatgat
    24661 agattttttt ataaagatag accttatatt ttttccagaa agagtcctat taaggggtga
    24721 aaatttgtta catttggatt aacaagtgtc ctagggatta gaaataactc tagtatagct
    24781 agatattttt gagtaactag aaatatcatt aggctaccca tatgattgcc agaaaagatg
    24841 gctgatgaat cttatttata ctgttgcagt aggcattgtc taggataaat aagctatctt
    24901 gatgggggaa attggaataa ttttagtaga aacattaaag gattatggat aagtagcgca
    24961 ggattaggtg atgcaatgtg ctaagttggc ttggtgttag cagtagtatt atttaacaat
    25021 ggaaagtaga ctaaatgaaa aataaacgtt atttttttga cacaatttta ataattttac
    25081 tgcttataag cacgatattt tgtgtcagcc cagtatttat aaaattggac atcttaggaa
    25141 ctccctctca tgccatctta acctttgtat tggcgatacc gttattctat attttgtctc
    25201 aatgcttaca tactttgcta ttactagttt cctcaatctt ttgtaaatta agaccaattt
    25261 atttttattt tatatttgtg atcattatag gagctaggaa atactatcga attctctttc
    25321 accaactaat gggatttagt ccaggaatag cagtgtttta taaggagagt caaacaacta
    25381 agaatctgtt taaattttac tacttcttgt actttacaac actaatttca tactattttt
    25441 tctttacttt tgtgtatgac aaaccgttgc ttttgcctct tatttcattt tctattatca
    25501 tagcattagt acaaaaactt tatagaattg agaatcaaca attatttctg ttaaaatcaa
    25561 aggtactaac aatactggaa tctaagaaga attgtgagtt taatcttcag gattatcatg
    25621 aaatttggaa attgcaatca aaatctgagt tgccatgcgt ggctttatct tatatcagtt
    25681 taatcaagcc atatctttca gagagtgtgc gtgaacaaat tgatttatta gaagttaagc
    25741 gatttaaaaa aataaataat ccaatatcac tttatggtat gttggatgtt ataaaattaa
    25801 atctatattt acggcattat aatgaaaaaa ataaatatga atcaatgtta aagaaaattt
    25861 tagaggtaag accagacttt gttttaatcg agcagaatat tgatgatagt ttaaatagct
    25921 cgcaaccatt atctttatct ttagccattt cagaaatcca acttttgctt gaagtgtata
    25981 tagggatcaa acatgtttca attaggagat aaaactagaa taatatttgc cattataggg
    26041 gcaagttgca tattagtcag tatgtatctt attccactta ttaaaactga gaataaattt
    26101 tgggaaatac ttttatttat attaggtgta ttgctaattg gaattgcgtt actaagtcaa
    26161 aaaaaataaa ttttgaaata gtattagtga gttcgcaatc atttattgct agtggtttag
    26221 aactgttaag tttcaaacaa taattgattt taaaccttag gtaacctata aaaacaaata
    26281 aggtagagaa aggatatctt atctaggtag ctaagtgata aaaacacagt cgtctatcac
    26341 ttgttaggaa acgatcctaa ctatgcttaa taaaaaagga gaaaataaat ggaactcgta
    26401 ttaccaaata attatgttgc tcttgagcaa gaagagatga tgtatcttga tgggggattt
    26461 tctattctga gatggcctgt tgcaacagcc attaatatag cttttaatgg tgttttaggt
    26521 ggaggagcaa tcagtctagt tagaaattat attcgtaatt atggtttgcg gcgagttaca
    26581 agcgcaattg ctggagcagc tgcaagatat gttggggtac gagttgcaaa tagagtggca
    26641 ggatttgcac tgtctgctat taatggattt gcagcttgga tgtcaattgg cgatgctatt
    26701 acaacaatct gggccaacaa tgatgtaaat aggagagacc caaatttaaa cgccttgtgg
    26761 taactagata tgggtattaa aatggaaaaa atttttgtta ttattttttt tgtatgtcta
    26821 tttatatcat ccataacttt tttagcctat gattttgtta gcgaagaaat aaaaaagttg
    26881 attatttgga tgaatgtcgt ttttttgatt ttaatcatag caatgataat ttatccaaaa
    26941 ttaagaaaat gataaggaca ctgtaaaatt atgatacgta aactaatcat ttttttatta
    27001 atgctccctc tttttgtctt gtggctagag ttgcatttgt tagtgagtaa cttgcaattg
    27061 aatctagaaa ttccccttga ttttgtggtt agtacgagtc ttgctttctg tagtttgatt
    27121 ttatcaaaaa tagttttaga catactatac gcattgaaag atttgtacaa gaaagaagct
    27181 cttattacga tttttccttt tatttttata ggtaggaaga aagtaaatgt gaggttctcg
    27241 ccctattttt cattccatcg taaaagtttg tcgcctgatg atttaagatc taggattata
    27301 tggagtttta ttcttgaaat tgctattatt ctagtattta ttttaaaaat tccttttgca
    27361 atcatcatgc ttactacaat atttttctgg actataatgg atatcaatca tctcgttttt
    27421 aataagacgg aatttctttt taatcaaaat aaatgggaaa aagaagattc gtttgaaagc
    27481 gatttgacga aaacgttaaa ggataagata caaaaatcag agctaagtta ttctgactta
    27541 atgtctcttc agctgtatga tgcgatgaac caatccacct ttttaacgga tagtgaactt
    27601 tttgaggata ttttgaaaaa aatcgaagat tctcataaca cccttctgtg tacaggtctt
    27661 gtcgagttac tgctgtatga aatgtctatt agtaacaata acaactggtc caacaaggtt
    27721 gataaaatta ggatacacct catcagaatc aatcaattag attttttcta ttatacaagt
    27781 tggttaaggc aaaattttga tttctgtatg aatagagagt atcataaaat gaaatctcgg
    27841 aaattattac tgagtaataa aaagatagtt taagttcgtc ctatttgtaa aacaaatgaa
    27901 acaatttcaa ctaaggagga gaaaacaaat ggaacttgta ttaccaaata attatgttgt
    27961 gattgatgaa gaagaaatga tgtatcttga tgggggagct tatttaagca agcgtgcttg
    28021 tcaaggaatt tgcgtagctt tagctatgag ttcaggaact tttatagcat tagctggagc
    28081 tgcagtttta accaaaaaac taataaacta tattaaggtt ggaggtcttg gaggctggct
    28141 tattggtgca gcagcaggaa aaatagctta ctgtattgga tatggtgctc ttaatagagg
    28201 ttgtgatatt agcgggaacc cttatccttg ggatggattt atatctgcga cagtaagatg
    28261 aataatgtag ataagattcg aaaaatacat attatcgtat gttgggtgta tatattttta
    28321 tcattcaggg cgattataaa tgacacggag tattttttgc ttattttttt agcttttatc
    28381 tactcaatag tatcactacc tctatattct gtgaaaaata aaatagtatc tatctgtcta
    28441 gccataaatt cgattctgtt aatgagtttc cccattttaa tcaataagtt tttcccagaa
    28501 agttttttga cttataccgt attaataagt gtttttatcc tagagttagc aatctttcat
    28561 ttaattgggg aagattttgc tactaaattg actaacgaat ataagaaaat tagtcagttt
    28621 agaagcaagg tgtctcaatc ttcttggata aaatatttag agatttctag ttttatatta
    28681 actatatttc catctattct ttacggtaca gttgataatc gtgtattggc tcttatcttt
    28741 ttgataaaaa tttgtgtaga tactacgata aaatttttat tcatcagatt atttgacaca
    28801 agtactttaa tgaagaggag aatatttttt cttttcgcat tggatgttat agcttactta
    28861 tttttaggat atcttttagt gattcaaaaa gcaggctatt tgttttcggt tttacttctt
    28921 ttttctaatt tttcagttcc atttatcaaa gcaaaggaat acgaattatt taaaaatagc
    28981 aagtaataga aacataggtt aaatcttaga acggcttaaa atcagatatg ataaagggaa
    29041 atagtcttat ctaggtaact aagtgctaca aacacagtcg aggatcactt gttaggatta
    29101 cattttaatc atgcttaata agaatggaga attcctatgg ggattgtatt actctgaagt
    29161 ttcgaatacc ttagttctcg tgattttgag ctgttctagc tttagaatcc ttcagaatgt
    29221 aaaattttaa gcagtcaaag acttagaata gcctggaaac atttatttta tagcaattct
    29281 aggcttagaa ttgctcatat atatgtattt gagctgctcg atagttagga cagctctatt
    29341 ctgagaaatc tgagctatca atgcttcaga atagtatttc gcaaatggtt tttattgaag
    29401 aggtgattgt tttatgatag tctaaaataa aactgattta atggagtaaa tggagaatcg
    29461 tcacatgaaa catttttttg caggaattgg tgagataaaa cttgttggct acttattgta
    29521 tatatgtgta ggactagccc ttctttttca tatatatgtc ataggttcgg aactgagttt
    29581 tgtgaaaata gtgttatcta ttttgggagt tatatttgta agtatgttaa ctattgctcg
    29641 aatttatcgg acttttctat aaagaatagt ttggacttga actgtatcta aaaacagagg
    29701 ttggtcgatt atcagcctct ttcttgtcgt tgaaaagagt gagatatatt gacttttgaa
    29761 aaaaatgtca taattgagtt gggataaacc taaaagtaat atagtagatt gaatctggaa
    29821 tagtccgtta tgactgttaa aatatttcta gaaattaatt tgactttcct aatcgatttg
    29881 ttcacatctt gtttcaatct actatacttt ctcgttaaac cgttcggcaa ttcatggtga
    29941 catggacaca tagtagtaag cacactatgt ggcttggcag agctaaaaac tgttcccttg
    30001 cgataagcct aataagcaca acatagggag ttagagaagc cgactctaat caaccacttt
    30061 gggcagtagt gagaactgcc ccgtgctttt ttattttgag aaaatatgga gtttgtcgtt
    30121 gaaattactt gattgtattt tggactatca agaaagattc aatggaaaaa catgtcaagt
    30181 atcaacgaat tataagtatt tagagatttt caaagtgaat ttttgcttga ctgatttaca
    30241 tcatttattt gacttataca aaatcacacg agattatgct agtcaaacaa aacctgctat
    30301 tcaagctggt gtttttattt tagaagattt tagaaatatc ctatgtacaa tgatgtaatc
    30361 gaaaggatat ctttatatga gtttatcggc gatatcttct atatctaagc tagcaagttg
    30421 ttgcatcgta gctagggatt tatctaaaaa tactatgaaa ttggacgtca tattttttga
    30481 ggataaaaat aaaagatccg cagttttagg tttacgaaga gacaaaagcg gagtatttaa
    30541 atcagttact ctacatttta caagcgctaa gaaatatgct aaagttcgta aaacagatgt
    30601 gaaagaaatg aaatggctat aaagattgtc cgcaggctta agcttgcgtt ttttgttgtt
    30661 taacgaaatt aaaaaacaag ctctctcatc ggaaatgttt ttataggaat gaaggaagat
    30721 gatgctatgt ttaaaaagag aatcgaaaag ggcaaaagta gtatctttat ctattttttg
    30781 gagtagaagc ttatgatata gaaatttgta ataaaaatgt aatataaaac atttgacaaa
    30841 tatttacggg gggagtatac ttaatataag tatagtctaa aaatgactat cagaaaagag
    30901 gtaaatttag atgaataaga aaaaaatgat tttaacaagt ctagccagcg tcgctatctt
    30961 aggggctggt tttgttgcgt ctcagcctac tgttgtaaga gcagaagaag ctcccgtagc
    31021 taagcagtct caagctgaga gagactatga tgcagcaatg aaaaaatctg aagctgctaa
    31081 gaaagaatac gaagaagcta agaaagattt agaagaagca aaagctgctc agaaaaaata
    31141 tgaagatgat caaaagaaaa ctgaagagaa agcaaagctt gttcaaaaag cggatgaaga
    31201 gcgtcaaaaa gcgaatgtgg cagttcaaaa ggcgtattta aaactccgag aagcacaaga
    31261 acaattgaac aaaagtccaa acaataagaa aaatgccgct caacagaaat taaaagatgc
    31321 attagctcat attgatgagg taacattaaa acaaaaagag gcggaagcga atttcaataa
    31381 ggaacaagca aaagtagttc ctgaagcaga taagttagct gagactaaga aaaaagcaga
    31441 acaggctgaa aaaaaagaac cagaacttgc taaaaaagta gcagaagcta aagcaaaagc
    31501 agaagaagct gagaaaaaag ctgttgaagc caaacaaaaa gtggatgctg aaaaatatgc
    31561 tcttgaagct aaaatcgctg agttggaata tgaagttcag ggactagaaa aagagctcaa
    31621 agagattgat gagtctgact cagaagatta tattaaagaa ggtctccgtg ctcctcttca
    31681 atctaaattg gatgccaaaa aagctaaact atcaaaactt gaagagttga gtgataagat
    31741 tgatgagtta gacgctgaaa ttgcaaaact tgaaaaagat gtagaagatt tcaaaaactc
    31801 agacggtgag caagctgaac aatatcttgt tgcagctaaa aaagacttag atgctaaaaa
    31861 agctgaatta gaaaatactg aagctgacct taagaaagca gttgatgagc cagaaactcc
    31921 agctccggct ccggctccta aaccagcccc agctcc
//
LOCUS       DBEJJE010000025        31810 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEJJE010000025 DBEJJE010000000
VERSION     DBEJJE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.25"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(137..484)
                     /locus_tag="ACL3F5_001117"
     CDS             complement(137..484)
                     /locus_tag="ACL3F5_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0514939.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(595..2370)
                     /gene="spxB"
                     /locus_tag="ACL3F5_001118"
     CDS             complement(595..2370)
                     /gene="spxB"
                     /locus_tag="ACL3F5_001118"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0514940.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNDEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2577..4820)
                     /locus_tag="ACL3F5_001119"
     CDS             complement(2577..4820)
                     /locus_tag="ACL3F5_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0514941.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSVTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4830..5201)
                     /locus_tag="ACL3F5_001120"
     CDS             complement(4830..5201)
                     /locus_tag="ACL3F5_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0514942.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5212..5607)
                     /locus_tag="ACL3F5_001121"
     CDS             complement(5212..5607)
                     /locus_tag="ACL3F5_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0514943.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5791..5889
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5973..6764
                     /gene="thiD"
                     /locus_tag="ACL3F5_001122"
     CDS             5973..6764
                     /gene="thiD"
                     /locus_tag="ACL3F5_001122"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0514944.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFIKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6973..7605)
                     /gene="thiE"
                     /locus_tag="ACL3F5_001123"
     CDS             complement(6973..7605)
                     /gene="thiE"
                     /locus_tag="ACL3F5_001123"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0514945.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7598..8401)
                     /locus_tag="ACL3F5_001124"
     CDS             complement(7598..8401)
                     /locus_tag="ACL3F5_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0514946.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            complement(8401..8925)
                     /gene="thiW"
                     /locus_tag="ACL3F5_001125"
     CDS             complement(8401..8925)
                     /gene="thiW"
                     /locus_tag="ACL3F5_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0514947.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8930..9622)
                     /gene="tenA"
                     /locus_tag="ACL3F5_001126"
     CDS             complement(8930..9622)
                     /gene="tenA"
                     /locus_tag="ACL3F5_001126"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0514948.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9633..10283)
                     /locus_tag="ACL3F5_001127"
     CDS             complement(9633..10283)
                     /locus_tag="ACL3F5_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0514949.1"
                     /translation="MVKVATQPPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10285..11670)
                     /locus_tag="ACL3F5_001128"
     CDS             complement(10285..11670)
                     /locus_tag="ACL3F5_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0514950.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11671..12231)
                     /locus_tag="ACL3F5_001129"
     CDS             complement(11671..12231)
                     /locus_tag="ACL3F5_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0514951.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12493..12581)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12790..13419)
                     /gene="thiE"
                     /locus_tag="ACL3F5_001130"
     CDS             complement(12790..13419)
                     /gene="thiE"
                     /locus_tag="ACL3F5_001130"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0514952.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKNDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13421..14203)
                     /gene="thiM"
                     /locus_tag="ACL3F5_001131"
     CDS             complement(13421..14203)
                     /gene="thiM"
                     /locus_tag="ACL3F5_001131"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0514953.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14446..15114)
                     /locus_tag="ACL3F5_001132"
     CDS             complement(14446..15114)
                     /locus_tag="ACL3F5_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0514954.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15329..15417)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15671..16807)
                     /gene="lctO"
                     /locus_tag="ACL3F5_001133"
     CDS             complement(15671..16807)
                     /gene="lctO"
                     /locus_tag="ACL3F5_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0514955.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17431..18921)
                     /gene="lysS"
                     /locus_tag="ACL3F5_001134"
     CDS             complement(17431..18921)
                     /gene="lysS"
                     /locus_tag="ACL3F5_001134"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0514956.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIKEITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19061..19195)
                     /locus_tag="ACL3F5_001135"
                     /pseudo
     CDS             complement(19061..19195)
                     /locus_tag="ACL3F5_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            19411..20091
                     /locus_tag="ACL3F5_001136"
     CDS             19411..20091
                     /locus_tag="ACL3F5_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0514957.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWRILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVELPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRFRHAGFG
                     NPSTLSGK"
     gene            20051..20728
                     /locus_tag="ACL3F5_001137"
     CDS             20051..20728
                     /locus_tag="ACL3F5_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0514958.1"
                     /translation="MQDSEIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20729..21487
                     /locus_tag="ACL3F5_001138"
     CDS             20729..21487
                     /locus_tag="ACL3F5_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0514959.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADQIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            21499..21741
                     /locus_tag="ACL3F5_001139"
     CDS             21499..21741
                     /locus_tag="ACL3F5_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGR0514960.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYATILN"
     gene            21783..22364
                     /locus_tag="ACL3F5_001140"
     CDS             21783..22364
                     /locus_tag="ACL3F5_001140"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0514961.1"
                     /translation="MSVDADNRAEYLISNKVDITLANFTVTDERKKQVDFALPYMKVS
                     LGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLD
                     GRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKL
                     GKENFFHKAYEKTLHPTYGDAAKADDLVVEGGH"
     gene            complement(22444..23091)
                     /locus_tag="ACL3F5_001141"
     CDS             complement(22444..23091)
                     /locus_tag="ACL3F5_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0514962.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23088..23786)
                     /locus_tag="ACL3F5_001142"
     CDS             complement(23088..23786)
                     /locus_tag="ACL3F5_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514963.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(23796..24548)
                     /locus_tag="ACL3F5_001143"
     CDS             complement(23796..24548)
                     /locus_tag="ACL3F5_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514964.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24548..25312)
                     /locus_tag="ACL3F5_001144"
     CDS             complement(24548..25312)
                     /locus_tag="ACL3F5_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514965.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25408..25812)
                     /locus_tag="ACL3F5_001145"
     CDS             complement(25408..25812)
                     /locus_tag="ACL3F5_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514966.1"
                     /translation="MKRRKIYSLFCVVTIASSLFLPTVLARQIGDYDLTLPRWGSDTT
                     SELEKENASAGINNNDSTGGGKTLNTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGD
                     NYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            complement(25992..26624)
                     /gene="pyrE"
                     /locus_tag="ACL3F5_001146"
     CDS             complement(25992..26624)
                     /gene="pyrE"
                     /locus_tag="ACL3F5_001146"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0514967.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSDLIHLAQEEGYITPEGLYLLKRFKEDQENWQEG"
     gene            complement(26658..27359)
                     /gene="pyrF"
                     /locus_tag="ACL3F5_001147"
     CDS             complement(26658..27359)
                     /gene="pyrF"
                     /locus_tag="ACL3F5_001147"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0514968.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEEPV
                     AAYHAIKDEWTQDWN"
     gene            27674..27772
                     /locus_tag="ACL3F5_001148"
                     /pseudo
     CDS             27674..27772
                     /locus_tag="ACL3F5_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28094..28807)
                     /locus_tag="ACL3F5_001149"
     CDS             complement(28094..28807)
                     /locus_tag="ACL3F5_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0514969.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28800..29639)
                     /locus_tag="ACL3F5_001150"
                     /pseudo
     CDS             complement(28800..29639)
                     /locus_tag="ACL3F5_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(29843..31027)
                     /locus_tag="ACL3F5_001151"
     CDS             complement(29843..31027)
                     /locus_tag="ACL3F5_001151"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGR0514970.1"
                     /translation="MNEQILISDEIDIDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLG
                     AGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILYTESNVGKEKINVLSEKIHK
                     YNSDVQVVPISIKVSSVEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISY
                     ISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIM
                     TNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRA
                     KTFIRSVCFCLLSGGVAFLSAIGQFTVIGTQLIVLFLGIIFAIYYAYYNKNIQTSLEN
                     IVWLFSSFEILFLLVNFRTFIQLPVDIFICMIIFLMLWIFIMLGIVCLSYYITLLFGK
                     EA"
     gene            complement(31199..>31810)
                     /locus_tag="ACL3F5_001152"
     CDS             complement(31199..>31810)
                     /locus_tag="ACL3F5_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HGR0514971.1"
                     /translation="ADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIANNYQI
                     EIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVLLFTS
                     YKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAFVIIY
                     FPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
BASE COUNT        10012 a         6711 c         5499 g         9588 t
ORIGIN      
        1 tgctttttga aagcagatga gtattatatg caatttcttt atataaaaag accggattgc
       61 tccgatcttt caatagttca tattctcaat ttctatttta aaaatagcta aggttaacgt
      121 caaatgacta cgcgacctat ttcatacgat aaaaatcaag cactagacca gcaggtcctt
      181 gaactaataa ggactctgtt ccccaatcgg ttacagttgg tccgtgtaaa acctttatac
      241 caagctcgtt caaccgtttg tagttctggt ctacatcctc aacctcgata tgaataatga
      301 ttcctgactg aaagttttcc aaaggaacca aatgattttg tgacaacata aggcagtgac
      361 taccaatcgt aaactgagca aaaccatcat cagcataatc tgccttttta tccaagatat
      421 gctccaagtc agcacagact tggggaacat ttgaaacgat aatatctaat tgatttaaat
      481 tcatttactc tcctccataa aaagaccgga ttgctccgat cttttaaagt tctgctctat
      541 gaaaatcaaa gaataaagtc tacaagtttc atatttgatt ttcggcgaga ggaattattt
      601 aattgcgcgt gattgcaatc cttcttcttc caagaagaga cggaatggta cgagttcttc
      661 tgcttcgtat ttttccttga aggctttgat agcttcttct gagtgaagtt ttggatccaa
      721 ttcaagtact tctactggaa gtggacggtg ttgagtgatg cgagcatcga tgacaacagt
      781 tttaccttct ttgttcaatt taacagcttc tgcaacaact gcatcgatgt cttcgatacg
      841 gtcaactgtg aatccaacag ctccttgagc ttccgcaatt ttagcgtagt cagcgtttgt
      901 gaagtctaca ccaaacaagt gtttgtttgt atcttcgtat ttgttcttga tgaagccgta
      961 ctcatcattt gagaagacaa ggttgataac tggaaggtcg tattgaacgt ttgtgataac
     1021 gtctgggtag cacatgttga atgctccgtc acccatgatg ttccatactt ggcgatctgg
     1081 attgtctttc ttagcagcga taccaccagg aagggcaata cccattgtcg caaagagcgg
     1141 agatgtacgc cacatgttct taggtgtcat gtgaaggtga cgagtagatg tttgagtagt
     1201 gttacctacg tcgattgagt agatagcgtc ttgatcagca tgtttgttga ttgcattgta
     1261 aacttgatac aattgcaatt caccctcagt tttaccttcg agtttgttca tgtaatcacg
     1321 ccagttttgg ttgttcttaa cgtttgcacg ccaccatgga gttgattcaa ctgggtttac
     1381 tttgtcaagg atagctttag ctgcttgacc agcatcacca aggattgaag cgtcaagggc
     1441 atgacgttta ccaagtttgt aagggtcgat atcaacttgg atgaattttt cagtgttctt
     1501 gaatgcttcg taaacttcag caaatgggaa gtttgaacca aggaaaagaa ctgtgtctgc
     1561 ttcaaagacc acttcgttgg ctggtttcca accaacacgg taagcagaac ctgtcaaacc
     1621 ttcatagttc cattcgaaag cttcaaagtt tttaccagtt gtgataattg gtgctttgat
     1681 tttacgtgac aattcagtaa tcacttcacc agctttaaca ccaccaaatc cagcatagat
     1741 aactgggcgt tcagcattgt tcaagatttc aacagctttg tcgatttcaa cttcgttcaa
     1801 agcaggagcg atgaatgagc gttcgtatga acctgaaccg tagtatgagt tttcgtcgat
     1861 ttcttggaaa ccgaagttta ctggaatttc aacaacagct ggaccttttt tagaaattgc
     1921 agcacggcag gcttcgtcaa ttacttttgg caattgctca gcgtaagcta cacgtttgtt
     1981 gtaaacagcg ataccgttgt acattgggtt ttggttaagc tcttggaaag catccatgtt
     2041 caattcgtta actggacgtg atccaaggat cgctaggaat ggagtgttat ccatagctgc
     2101 atcgtaaaca ccgttaatca agtgagtcgc acctggacca cctgaaccaa ctgcaacccc
     2161 gattgagccg ccgaatttag cttgcataac cgctgcaaga gcacctgtct cttcgtggcg
     2221 aacttgtaag aaacggatat ctttgtcttc agccaaagcg tccatcaatg agctgagtgt
     2281 tcctgatggg ataccgtaga ttgtatctac gccccatgtt ttcaatacgt taagcattgc
     2341 tgcagatgca gtaattttcc cttgagtcat aatgataact ctccttcaat ttttttaaac
     2401 ttggagaata cgattacata gaattggaaa cgttctccaa atttttacta ttccactgta
     2461 tcatatttat gctgactttt ctaaaaatct gctcaaaact ctctattctc tattctaata
     2521 cagttttgaa agtgttgtca tttctgtttt ataacaaaga aatctagtca ttacttttag
     2581 tctattttac taaaatttaa cagaagggaa ctggtcagaa cagatacaga actaaaggcc
     2641 atggctagac ctgccaattc tgggttgaga gccagtccaa cacctgaaaa gactcctgct
     2701 gcaatcggaa ttccgacaac attgtagata aaagcccaga aaagattgag tagaattcga
     2761 tgaaaggttt tcttactcat atcaaaggca cgaaccactc ctaaaagatt attggttgtc
     2821 aacaccaaat ctgctgactc gatggcgata tctgttccag cacccatagc aattcccaca
     2881 tctgctacac taagggcagg agcgtcattg ataccgtccc caacaaaggc tactttgcca
     2941 gccgcttgca gtttatggat ttcatgggct ttttcttctg gcaagacgcc tgcaatgacc
     3001 tcttcaattc cgatttgatc tgcaatagca cgcgccacac cagcattgtc tcctgtcagc
     3061 atgactgttc ggagaccacg tttttttagc tgactgatgg ctagcttagc attttcctta
     3121 ggaatatctt gcaaagcaag caagcctttg atttcattgt caacagctaa gaacacaact
     3181 gtcttagctt ctttttctag ttcttctagt ttatcttgat aagtattaga aatatccatg
     3241 ccatccagca ttttagcatt tccaagtaaa acttgttttc cattgattcg ccctgaaaca
     3301 cctttcccgt gcaaggtctg aaaattttca acagtttgaa actcaagtcc agcttcactc
     3361 gctcgcttaa cgatagcctc agccagtggg tgttgagaag catcttccaa ggaggctgcc
     3421 aacccaaaca cttctacttc gtcgccgatg acatctgtta ccacaggttt cccttccgtc
     3481 aaagtcccgg tcttatcaaa gacaagagtt tgaactttct ggatttcctg taagacagtt
     3541 ccatttttga ggagaacccc catcttggca ctacgtcctg tccccaccat aagggctgtc
     3601 ggtgttgcaa gtcccaaggc acaaggacag gcgataatca aaaccgccac tccgtagaga
     3661 agagaggaca caaagctagc tccaagcaca accacactat ccctgagcaa gacgaaccaa
     3721 acccaaaagg tcatgattcc taaaatgaca actactggga caaaaatccc tgaaatctta
     3781 tccgtcaagt cctgaatcgg cgcacgactt gtctgagctt tcttcacaaa atccacaatc
     3841 tgagccaaaa cagtctctga gccaactttt tctgctctaa agacaagcgt tacactatga
     3901 ttgatggttg agccaatgac agtatctcca actgtcttgt ccacaggcag actctcacct
     3961 gtcaccatgg attcgtcaat actagagaca ccttctacta cgacaccatc aacagcaatc
     4021 ttttcaccgg gacgcactcg aatcaggtcg cctaccttga cttgttccaa aggaacttgg
     4081 acataactat catcactcaa gacttctgcg gttttagctt gcaagtccag taatttctcc
     4141 acagcttggg acgtattttt tctcattttt tcctcaaaaa ctgctcccaa aagaacgaaa
     4201 aagaggataa atccagcact ttcgaagtaa acagggagac cagcaaagag agcaactagg
     4261 ctatagaaat aagccactag agttcccagc gcaaccaagg tatccatgtt ggcattgtgc
     4321 tttttaaaac tggcccaagc actctggata tatggcttac ctgcaactaa cataataggc
     4381 gttgttgcta aaaaggttcc ccaatgcatg acttgatgac taatgctacc tgtcaacatc
     4441 ccaatcatga gaatcacaag aggcacagta aagatactag taatccaaaa acgttgcagg
     4501 agagatagag attttcgagt cttctcaacg actgtatagc ttcccttttg catcttcatg
     4561 ccacaagaaa attcatgtcg ccctaattct tgaggcgtaa aacgaatgac tttctcctca
     4621 tctacgccga ttggttccaa gataccttct tcttcaaaca gaatttcctt ataacagttt
     4681 gaaggagtag cacgatgaaa ggtaatctca gctggaattc ccttttgaag ctggatatgg
     4741 gctggatgat agcctttttc agctcggata cggatttttt gaatgccatt ttctaagctt
     4801 gctttcacaa tttctgtcat agtctccacc tactctacaa tcatcttgcc gtgcatcatg
     4861 ttcataccac aagcaaagcc aaactctcca gcctgttcag gcgtgatttc cactacatac
     4921 tcttccccca ttggcaggtt cgcatgtaca ccaaaatctg gaaaaacaat ttgatccaga
     4981 catggtgaag gatccttgcg gtcaaagaca atgcgggctg gcactgattt cttgaggaca
     5041 atcaactcag gagtatagcc tcccatgact tccactcgaa tctcttggta tccgtttttt
     5101 tgctgggctt tttgtccaga tttttcaggc tttttgaaaa accaaaacaa gataaacgcg
     5161 ataagggcaa tacaaataat ggttacaata ctatttaaca tggcgtctcc tttacataca
     5221 attacatctt acttctgtta cagcacttga tttcttctct gaaatcacag cttccaagtc
     5281 ttccaagtca gtctgagtaa attcacattc tacaatcaag tcagccaaca aattcctaat
     5341 cctacgggaa caaaccttgt ctttgatatc ttggacaagt aaatcccgac tttggtctag
     5401 agttaaaagc gctgaataaa caaagaactt gccttctttt ttccgagtca aacactcttt
     5461 ctcaactaga cgagccaaaa gtgtctgaac cgtggacttg gaccagtcaa accgctctgc
     5521 caaaacccta attaaatctg tactggtctg ctccccctgc atccaaataa tcttcatgac
     5581 ctgccattct gcatctgaaa tctgcattac catacctcca aaatctacat ttgtcaatta
     5641 cactcatcag tatactttta aaatctacat ttgtcaatta tagaaataat attttcttcg
     5701 aaaaatagaa ttttaatcat ttgaaaaacg atttgcagtc aaatattact atataaacaa
     5761 taaaaatatg ctatactaaa gaaaaaagaa aacaaccact aggggtgcgt aaagctgaga
     5821 ttaacgactg ttagatccct ctgactcaat ctaggtaatg ctagctgatg gaagtggaaa
     5881 tgataatggg gactagcagt cttctattgc ctttctaaaa cagactagct tgttcttaag
     5941 aatacaaact tcagttggtt gggaggtttt agatgactta tttacccgtt gctttgacca
     6001 ttgcagggac tgaccctagt ggtggtgctg gcattatggc agatttaaag tcattccaag
     6061 cgagagatgt ctatggaatg gctgttgtaa ccagtcttgt cgctcaaaat accagaggtg
     6121 ttcagctaat cgagcacgtt tctcctcaaa tgttgaaagc ccaattggag agtgtctttt
     6181 ctgatattcc acctcaggct gtaaaaactg gaatgttggc tactactgaa atcatggaaa
     6241 tcatccaacc ctatcttaaa aaactggatt gtccctatgt ccttgatcct gttatggttg
     6301 ctacaagtgg agatgccttg attgactcaa gtgctagaga ctatctcaaa acaaacttac
     6361 tacctctagc aactattatt acgccaaatc ttcctgaagc agaagagatt gttggttttt
     6421 caatccatga ccccgaagac atgcagcgtg ctggtcgcct gattttaaaa gaatttggtc
     6481 ctcagtctgt ggttatcaaa ggcggacatc tcaaaggtgg tgctaaagat ttcctcttta
     6541 tcaagaatga acaatttgtc tgggaaagcc cacgaattca aacctgtcac acccatggta
     6601 ctggatgtac ctttgctgca gtgattactg ctgaactagc caagggcaag agtctttacc
     6661 aggcagttga taaggccaag gcctttatca caaaagctat tcaagatgcc cctcaactcg
     6721 gtcatggttc tggtccagtc aaccatacaa cttttaaaga ttaagaaaaa aactctctag
     6781 ttcccacttt aagggaatta gagagttttt atactcttcg aaaatctctt caaactacgt
     6841 cagcttccat ctgcaacctc aaaacactgt tttgagctga cttcgtcagt cttatctaaa
     6901 acctcaaggc agtactttga gcaacctgcg actagctttc tagtttactc tttgattttc
     6961 attgagtatt aattaggaaa gaatgtcatg caactttgtt aaaaaggctt gcgtttttgc
     7021 ctcaatatct tctgcttgca tcaaatcacg tacaacagct acaccagcta tgccagtgcc
     7081 cataagctga tcaatattct ccgaagtcaa gcctccaata gcaactactg gaatggcaac
     7141 cgtttggcaa attgttttca aggtcgatat cagagtaatg ggcgcatttt ccttggtggt
     7201 ggttgggaaa atggctcctg tacccaagta atctgcacct gatttctccg cttccagagc
     7261 tcttttaacc gttttagcgg tgacaccgag gattttttca ggacccaaga cttgtcgggc
     7321 aaccgaaact ggtaattcat catctccgat atgcagacct gctgcatcaa ccgcaagaca
     7381 aacatccaac cgatcatcga ttatcaaggg tacctgataa gcatctgtta tttccttgac
     7441 ttgttttgcc agttgataat attgattggt tgtgagattt ttttctcgca attggactat
     7501 ggtaacccct gaacggcagg ccgtctcaac ttttgcaaga aagctttcca cggaatcttg
     7561 atagcgattg gttaccagat atagtctaag tgcttctcta ttcataagcc tctcctttga
     7621 tggtatctag ccaattttca tctcttctta ggagcgaaag ctgattgagt acttggtaac
     7681 gaaattcttc caatcccatt ccttgaacaa ctattttctc agcagcgata ttgagataag
     7741 agactgctaa gcaagaagct tcaaaaccag tctttccttg gctgagaaaa acggctgtta
     7801 aggctccaac caaatctcct gtccctgtta tccagtctaa ttcagtacag ccattctcca
     7861 gtacagcgac ctgatttttc gaaacgacga ggtccttggg gccagtaact aagaatgaca
     7921 taccaggata ggtctgacac cagtctttca agacttgaag caaatcctcc gtttcttgat
     7981 ctttagcact cgcatcgacc ccaacgccgt ggtgctttaa tccaacaaga cttcgaattt
     8041 ctgacatgtt tcctttaatg accgtaggtc tatagtctaa aaggtcttta actaagctct
     8101 tacgaatgga tgaagtcgtt acgccaaccg catctactac catcgggaga gaagattggt
     8161 ttgcatacga agctgccatg cggattgctt tttccttctc agctgacaaa tgccccaaat
     8221 tgatgaagag agcctgactt tgcttagtaa aatcaagaac ctcacgggga tcatctgcca
     8281 tgacaggttt gcatcccaga gccaaaatcc catttgccag catctcacaa gaaatctcat
     8341 tggtcataca gtgaattagg gaactagagc ctataggaaa gggatttgta aattcctgca
     8401 tcagtctatc ctttcactaa agaaatatcc ctgcactttt ttaaagaatt cctgcttgat
     8461 taaaaatcga aaggcaataa aggaaatcgc tgtaccaatc aaggttgctc cgaaaaatcg
     8521 aggcgtgtag ataaaccagc taagcttagc agctgatcct gtaaagagta ccataacagg
     8581 ataggaaaca atagaaccaa taatacctgt tcccacaatt tctcccaagg cagaaaagta
     8641 aaattttcga ccgtacttat aaaagagacc tgctagaagg gctccaaaag tcgctcctgt
     8701 gagagctaaa ggcggaatcc cttgagtcgt catacggata aaggctgtca ctgtagccat
     8761 agccaaggca taaacaggtc ccatcatgat tcccgctaga atattgacta cactggacat
     8821 cggtgccatt ccctcaattc gaaagatagg tgtaaggact acatcaaggg caatcatcat
     8881 agataaaatg gtcaatttgt gaacttgtag ttggtgcttt ctcatgtttc tattcttctc
     8941 ctttttctaa agactgtaaa tcgctcttcc atgtctggtg ttggtaagcc atctcccaaa
     9001 acttggcttc catatgaaca ctgatgtgga aggcatctag cattttttgc ttatctgtct
     9061 catcactttc tcgatagagc tgattgacca gtgctccctc ctctctgatc tgttgctcta
     9121 actcatccgt aatataagtt tcaatccatt gttgatagag aggatttggt gatggtttaa
     9181 gattaagtga tttgcctata tcatggtata accaaggaca aggaagcaag cttgcaaaag
     9241 cgatggctaa gttcggctct gcaaattgcc tataaatatg agaaatgtaa tgataacagg
     9301 ttggagcgat tggatgttgc tccatttcct ggtcgctgat ttccaattcc ttgaaaaatt
     9361 gttggcgaat aaataactca ccctccacta aaccctgagc attttgtttc aagagtcttt
     9421 tcatctcttg gtttgaagtc ttatcagcca aaagatgata gatttctgag aaggccttca
     9481 gatagtaggc atcctgaatc aggtaatagc ggaaaatggc aggttctaaa ttcccctctt
     9541 gtaattgtaa aataaaggga tgatgaaagg aagcctgcca agctttcttg gataattcca
     9601 tcgcaatatc tgtaaattcc ataataactc ctttataaaa atagactggt ttgaagcaat
     9661 aaaaagaaaa gcaggtagat taattttgtt tttttaggaa tataaaaagt ccgatagcta
     9721 ttcttcaact gtgcatgttc gtcatatccg tgagcagata gagctctcag gtaaagatgg
     9781 cgccacctaa agactgtcat cagaacctta ctgtaaatca agggcgacca aaaatgtagt
     9841 ttttgaccac gtaataggca agcttctttg agggacttga tttcttgctg aatgagagga
     9901 aaagaattga ataccacaat caaggcatag gaccaagagc gtgatagccc cttttgagcc
     9961 aagtacaaga gaagctcttt tagtgaaata gaggaaacaa agacaaggcc gatacaaact
    10021 gtcacaaagg ccctcgttcc aagcatgact gcctgtgaag catctccgtg taactgaact
    10081 gcccagtagt tggcaaaaga tggtaaaatg gcaagtatga tcatccaagc taacatttta
    10141 aatcgacggt aatagagcat aaagagaata caaaatgcga ctaccgaaag attcagagca
    10201 atcgaaggaa tgaaagatgt ttccaaggat aaaatcagca agaagagact gataatcggt
    10261 ggctgggttg ctactttgac catactatct cacctcccct tgggtattgc tactctgaga
    10321 tgtaagtggt ttggtaatgg tcacttcttt cacatgccga agaccctgac tagtcatctc
    10381 aatccaataa tcaaccacag aaatcaaagg gtctaaacga tgactaatga gcagaaaact
    10441 tcttccttga ttcctctcct ccacaatcca cttgcaaaaa taatggcagg ctctatcatc
    10501 caaacctgca aaaggttcat ctagcaagat cacggaagcc ttactggtca agatggtcag
    10561 gagctgaaga attttttgct gaccaccact taattgatag ggactcttat cgactgcctg
    10621 ctccaaatca aaatatcgta aagcttgaaa aatccgctga tttctttcag aatcaggtcc
    10681 atctaattga agctcctctc gcagactgac tcggataaac tgcttctcag cttcctgaac
    10741 aacaccagtc agatcacgat acaaactctt tttctttttc aggaccgaac ccttccaagt
    10801 aatgctcccc ttatactttt gaaattgaag aatagaccga aagagggttg atttcccgac
    10861 accattgtca cccaggatac aggaaatccc ttgatagaat gtgaaatcag caattgaaaa
    10921 gagggggcga ttaccaagct caccagtcac acggttcata tggaatagtt ccgggctaga
    10981 agcaacttcc tttgaagcaa cctgtgtcat ctcataggaa gggatttgaa acacttccct
    11041 tagttttccg tctcttagct ccaccatatg gtcgatatag gctttatagt cagataaatc
    11101 atggtcgcac aaaataactg tcttcccatc atagaccaac tcttttagaa tctccaatat
    11161 ctcgattctg ctcttgcggt caatggaagc gaagggctca tccaagagat agaccctagg
    11221 attcatggca aagaggacag ccagcgctgc tttttgcttt tccccacctg ataagtgatg
    11281 gatgagacgg tgcaagatgt ccttgcaacg acattgctgg acaacctctg ctattttaga
    11341 atcaatttcc tgaaggtgat agccgatatt ttccatggta aaaaccaact cctcaaacaa
    11401 gctctccatg gtaaattgat gattaggatt ttgcaagaga ataccaaccg tctggacacg
    11461 ttcgacgata gaaagctgac tgacctcgct cccatctatc aggacttgac cgctataggg
    11521 aagagaacta acttgggcaa tcatttgaaa gaggctggat tttccagacc cactactccc
    11581 aactaacaag gtaaaggctt gcgcatgaaa agtaaaatca aacggctcag agaagattgg
    11641 ggactgaatc gctcgtagtt ccagacccat ctatgctttt cctccagttg caaactgatg
    11701 atagagtttg acaatggcac gaaccaagat ggtacagaag aaataaacag aaataaaacg
    11761 taccacaagc aaggaaagga caaacggaag ggaaaaggcg tagtaaccta acttaatgta
    11821 ttcatagaca aagctaacaa gcgtaatccc aatactatta gcagttagag agagccaact
    11881 ttcatagcga ttcttagtta cgataaaacc aaattcactt cccaaacctt gaacaaagcc
    11941 agacaaaaga gctcctagac caaattggct accataaagg acttcagcaa gcgcagctag
    12001 cacttctcca atcgttgcac ttccgactct cggaacaaag atggcagcaa tgggcgcagc
    12061 catacaccag agaccgaaga ggatttcatt ggcaaaggcc tgcaaaccaa gaggtgttaa
    12121 gagtagactg agaatattat acacatatcc tgaaccaacg aaaaccccac caaaaaagat
    12181 agacaagaaa gcaagcaaga taacatcttt taactgccat tttttcaaca taaaaaactc
    12241 ctttttttaa agaaaagtgg ggcactcaag aagaccgacc taaatacttt gtatagcaga
    12301 ctgaatttag aacagtacac aagaacacta aaatatttct agaaattaat ttgaattttc
    12361 taattgattt gttcgcatct tatttcaatc tactatatca tcttcatcca gtttcgtaaa
    12421 agaaaaaact ctaattacag atacaaatta gagttcagct tacaagatta gacagttctt
    12481 ttcgacatac gaaaaaaaca tttcacattt cccttcgcca gtcttaactg tatcaggttc
    12541 aatgggtatc atctcagcct aaagcacccc aaatgtcttt attatttaat tatgtgatta
    12601 ttataacaca cattttatac tagttcaaga aattgaactg gaaatacagc cttgcactca
    12661 caaagacagc agatctttct tttgcaaaaa acaaatgacc tgtttgatga attagccatt
    12721 caagctgaat ctggacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag
    12781 gatagatatc tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga
    12841 tattgccgaa atgattgaaa cgccatccat attggtcttt ataatgtctt taatatgttt
    12901 cgtctgtatc ccaccaattg caactaaagg catttgtggc aatagttttc tcatcaattc
    12961 aagaccttca taacctatag taccaccagc atcattcttt gactgggtac caaatacagg
    13021 cccaacacct acataatcta catattcaac ttttgattgt tgaaattctt cttcgtttct
    13081 tatagaaaga ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc
    13141 atcttgacct acatgtacgc catcggcgtc aatttccatt gctaaatcta tatcgtcatt
    13201 aacgataaat ggaacattgt attttttaca aagttcttta atttggatag ctagctcaag
    13261 tttttctaag ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc
    13321 accttttaag gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc
    13381 acaaataaaa tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt
    13441 cctttacatc ttcatctgta atctcgtata aggcatttat aaattcaact ttaaatgtcc
    13501 caggaagatg tccatttgga cgtttttctg ccatttctcc agcgatattg taaaccaaca
    13561 ttgctgtttc taatgatttc aattcttgac ctttttctag tccgataaag cttgctacta
    13621 cagctcctaa taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa
    13681 tcattaccac ttctccatta acagcaatgg catccacttc acctgttact actattggaa
    13741 tattgaactt ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat
    13801 ctactccttt agatgccaca tctattccta ctaaagaggc aatctcgcca gcatttcctc
    13861 taatcgctgc tagtttataa ttgttgatta gatcatctgc tacttttttt ctatattctc
    13921 ctgctccaca ggctacagga tctaaaactg ctgggacatt atatttctct gcaattttca
    13981 gagcagcttg gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac
    14041 caccagcata ctttaacaaa tcctctaaat ctgctggaaa ctcactcatg gctggtgagg
    14101 cgcccagtgc tactaatcca tttgctgtga aattttttac tacatcattg gttatacaaa
    14161 tgaccaatgg tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt
    14221 tcactttata cgatctactg atttcgattt atttctatct ttcgttaaga atttttttca
    14281 tttacattga atgatttata ctcaatgaaa atcaaagagc aaactaggag gctaaccgca
    14341 ggttgctcaa aacactgttt tgaggttgtg gatagaactg acgtggtttg aagagatttt
    14401 cgaagagtct tacctcatca aatttgtaaa tatcatgagc cttctctaga catcgtaacc
    14461 aatatcaaaa aaagctaatt ctaaagcgac tgcttgattc cagcgttgct gaagttctgt
    14521 caaatcttct cgatttttat cgacacgatt gagttcgtca accagaaatt gaacccactc
    14581 tgcaaagaaa ggacctctgt ggagattgat ccattccgaa tgaatataga cttcaggtaa
    14641 agccaaatct ttagaacccc agtctaaata gagaccttct gcaatgacca gcatgaccaa
    14701 aagatgggca tagtctgatg aagccaccgc cgaatacatt agatcctgaa aggcttttgt
    14761 tacagggtgc aaagtcactt ctagatagtc attctctgct acttttaact ctttaaaagc
    14821 cttttggaaa taaccatctt catctgcttc aagaaagcct agttgcttgg caaaacgaag
    14881 cttggattca agtttatctg cgtgagctac gcaggcaccc agcatggata agaaggcatc
    14941 aaagaagtga taatcttgaa tcagatagtc ctttaagacc ttattctcaa ttgtccccgc
    15001 aaaaagttcc ttaacaaaac gatgattgat tgcagcctgc caatccttct gactgctttt
    15061 taataattct ccaacagtca aacctggctg aaatgcatag tcttgtgttt ccatatttac
    15121 ttctcctctc tttacttgtt agtaattaat aaaacaccaa gaaatatcaa gcaaaatcgt
    15181 aattccactt gatcctttta aagcacatcg agagcatttg cagagagcta actaaacaag
    15241 cctatccagt ttatataaac aaaaaactcc aattacaatc aagaattaga gttgacttac
    15301 aagattagat cgttcatttc gccatacgaa aaaacgtttc acatttccct tcgccagtct
    15361 taactgtatc aggttcaatg ggtattatct cagcctaaag caccccaaat gtctctatta
    15421 tttaattact gaaccagtat agcaaaaaat gaaagcccta gcaagatatt tgaccgaaaa
    15481 atatctttat atataatata ttgaaactag aatagtagac ctctacttct aaaacattgt
    15541 tagaaatcga tttaactgtc ctgattaatt tgtcctattc ttatttcatt ttattatagt
    15601 tttcgatagc gatttattct tccaatacac gaagaaaaac ctccacattc agtggaggca
    15661 atctgtttta tcaatacaat tttaagtcac gagggtcaac tgggaaggtt gggttgtatg
    15721 gattgtgacg gagcttaaag tgtttgacat cttcaatggt ctgagctcca gacaattgca
    15781 taactgtctt caattccgca ttcaagtgtt caaagacttg acgcacaccg acactaccac
    15841 cgagagccaa gccataaata acagggcgac caatagctac caagtctgct cctgaagcca
    15901 aggctttaaa gacgtgttga ccacgacgaa caccagagtc aaagacaatc ggcacacgtc
    15961 tatcaactgc ttctgccact tcttgaagcg agtcaaaggc agctggtcca ccgtcgattt
    16021 gacgaccacc gtggttggtt acccagatac cagaagctcc tgcagcaagt gaacgttcaa
    16081 cgtcctcacg gcattgtggt cccttgacat acacaggaag accagagtat tcagcgataa
    16141 attctacatc gcgtggagac aagcgttgtt tagctgattt gtaaacaaag tccattgatt
    16201 taccagcacc ttctggcagg tattcttcaa caatcggcat gccaactggg aagacaaaac
    16261 cattacgctt atccacttca cgattccccc ctacagtagc atctgccgtc aagacaatcg
    16321 ctttataacc ttcagccttc acacggtcca tgatgtggcg gttgataccg tcatccttac
    16381 taaagtaaaa ttgaaaccaa tgaggtgtcc cttgaagggc ttcagaaatc tctggaaggt
    16441 caacagtaga gtaagaactg gttgtataaa gagaaccaaa ctcatgcaca ccacgcgcag
    16501 tcgccacttc cccctgttca tttgccaatt tatgagccgc aacaggtgcc ataatgattg
    16561 gtgaagatag tttttcacct gcaaattcaa tctctgtact tggattttct acattgcaaa
    16621 gtgtatgagg aacgatgagc ttgtggttaa aggcacggat attctctctt aaagtgaaag
    16681 tatcttccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    16741 ttggctccaa atcataggta ttgatgaagt ctacatgacc ttctgcattg cttgttttgt
    16801 atgacataaa ctgtcctcct cgattaagta agcgtttgct ttttactata caactataat
    16861 aactcttttt tcaatcattt tcaagagttt tgcttaaaaa ccatcttatt ttttcataca
    16921 atatactagc cctactttcc ttaaactcta aaccttagtc tatattaagt gaatcgttga
    16981 gattttttgc tgccaggcat ttgaactact tttttatttg ctgattctat ctactaatac
    17041 tataaaaaac aagtgaataa gacaccagaa catcctctaa taggacctat ggacttatat
    17101 cagtcccata tatactgttt aagcaagata ctatcctagt tgacgctaac ttcctatccc
    17161 acttattaat tttttattta tagtgaatct gaacaaatca attggggaat ccaagtcaat
    17221 ttctagtact ttttgaaaag tttcagcgta ctatcgtaaa atgaaataaa acatgcacaa
    17281 attgattagg gaatttaaac caatttctaa cagtgtctta gaaatcaaag tgtactattt
    17341 caacttcaat atactacact tcattttctc cttaaattca gtctcttttt gaatcaaaaa
    17401 atcctctggt aagaggcaga ggataagaat ttatttcatt gttgggaaga gcaatacatc
    17461 acggatagtt gttgtatcag tgaggagcat gcagagacgg tcgataccga ttcccaaacc
    17521 acctgttggt ggcataccgt attcaagagc ttcaatgtag tcatagtcga ttcctgtcgc
    17581 ttcatcatca ccaagttctt tggctttagc ttgggcttca aaacggctaa gttggtcgat
    17641 tgggtcgttc aactcagtaa aggcattacc gtactcctta gtcatgataa agagctcgaa
    17701 acggtcagta aagcgttggt cttcaggatt tttcttagcg agtggagata cagctactgg
    17761 atgtccatag acaaaggttg gttggattaa agtttcttca acaaactctt caaagaaggc
    17821 attgatgatg tgaccaacct cagtgtagtg tttctcaact ggaactttct tctcagcagc
    17881 gatagcttta gcttcttcca aagtcatgtc ttgccagaaa tcgacaccag taatttcttt
    17941 gatagcatcc accatatgaa cacgcttaaa tggtttgtta atcttgattt cagtaccttg
    18001 gtagttgact gggccatcac ctttgactga tttagcagcg tgttggataa tgccttccgt
    18061 caagtccatg atgtcttgga aatctgcata agcttggtaa acttcgatag aagtaaactc
    18121 agggttatga gtagcgtcca ttccttcgtt acggaagata cggccaattt catagacacg
    18181 ttccatacca cccacaataa ggcgtttcaa gtgaagctca gttgcgatac gaagcaccat
    18241 gtcaatgttt tgggcattgt ggtgggtgat aaatggacgg gcagcagcac caccggcttc
    18301 attatgaaga acaggtgttt ccacttcaag gaatcctttt tggtcaaggt aacgacggat
    18361 ttcagagatg atttttgaac gagtgacaaa gcgttcaaag ctttcacgat tagaaatcaa
    18421 gtcaaggtaa cgtttacggt aaattgtttc aacgtctgtc aaaccatgga atttctcagg
    18481 aagaggacga agagccttag acaagtgtgt gatgtgggtt gccttgatag agagttctcc
    18541 catatccgta cgcatcactt caccttcgac accaaggaag tcaccaagat ctgctttttt
    18601 gaagatttcg tagttttctt caccgacagc atccttacga acgtagatct gaatctggcc
    18661 ttcgcggtct tgaaggtggg caaaaccaac ttttccttta ccacgtttgg ttatcaagcg
    18721 tcctgcgata gtagctgttt cgtttttatc gtgtaattgt tctttatcga ggttggcata
    18781 tttatctttt aattcttgtg aatttgcagt acgttcaaaa cgttttccga aaggatcgat
    18841 tccttgttcg cggagcgcag ccattttttc acggcgaacg atctgctggt catttagttc
    18901 ttccatatgt tctgtagaca tgggatcctc ctagttttac tcaaaattga atacgatgag
    18961 tcattttttg cgataccccc attttatcat aaataagcaa gaaattcacg gataatcttt
    19021 aaaaactaaa aagaacctga cgctaaaatc actggaaaga agtgaaagta tctcccgccc
    19081 cactagcgat atagccaaat gctgctttag gaataacttg ttgcgccatt ggctccaaat
    19141 cataggtatt gatgaaatct acatgacctt ctgcattgct tgttttgtat gacataaaat
    19201 gtcctcctta ataagtaagc gtttactttg tatattataa aaatatctta actctttttt
    19261 caaaactttt caaatatttt gtttggaaat ttcagaaatt ttatgtctat ggtaaaaaat
    19321 ccttataacg gcaataaaaa atagatatta tccaaagaag attttaagtg ctacaataac
    19381 tgtattattt ctagatggga ggttctattt ttggattggt ccattgttga acaatatcta
    19441 ccactatatc aaaaggcatt ctttctgacc ttgcatattg cagtttggag aattttggga
    19501 tcctttctgc tcggtttaat cgttagtatc atccgacatt atcgaatccc tgttttggcg
    19561 caagtagcga cagcctacat tgaattgtca cgtaatacgc cccttttgat tcaactcttc
    19621 tttctctact tcggtcttcc ccgaatcggg attgtcctat cttcagaagt ctgtgcaacg
    19681 cttgggcttg tctttttagg aggctcctat atggcagaat ctttccgaag tgggctggaa
    19741 gccatcagtc aaacccagca ggagattggc ctcgctattg gtctgacacc tctacaggtc
    19801 tttcgctatg tggttcttcc gcaagcaaca gcggtggaac tcccctcctt tagtgccaat
    19861 gtcattttcc ttatcaagga aacctctgtt ttctcagcag tggctttggc cgacctcatg
    19921 tacgtcgcca aggatttgat tggtctctac tatgagacag acattgcgct agctatgttg
    19981 gtagttgctt atctgatcat gctgctaccc atctcactgg tctttagctg gatagaaagg
    20041 aggttccgcc atgcaggatt cggaaatcca agtactcttt cagggaaata atctcctgag
    20101 aatcttacag ggattgggcg ttacgattgg gatatccatc ctgtctgtcc tcttatccat
    20161 gatgttcgga acagtcatgg gaatcatcat gacctcccat tctagaatca tacgattttt
    20221 aacacgattg tatctggaat ttatccgtat catgccccag ctggtgctac tcttcatcgt
    20281 ttactttggc ttggctcgaa actttaatat caatatctca ggtgagactt cagctattat
    20341 cgtttttacc ctctggggaa cagctgaaat gggagacttg gtacgtggag ctatcacttc
    20401 tctccctaaa catcagtttg aaagtggaca agcactcggc ttgactaatg ttcaacttta
    20461 ctaccacatc atcatcccac aagtcttgag aagactgcta ccgcaggcta tcaatcttgt
    20521 cactcggatg attaaaacca cttcattagt tgttttgatt ggggttgtgg aagtgaccaa
    20581 agttggacaa caaatcatcg atagcaatcg cctgaccatc ccaactgctt cattttggat
    20641 ttatggaacc attctagtct tatatttcgc agtttgctac cctatttcca aactatccac
    20701 tcacttagaa aaacattgga gaaactaaat gtctgaaact atcttagaaa tcaaggaact
    20761 aaaaaaatcc ttcggagaca atcccatcct ccaaggactt tctctagaaa ttaaaaaagg
    20821 ggaagttgtt gtcatcctag ggccatctgg ttgtgggaaa agtaccctcc ttcgttgcct
    20881 caacggctta gaaagtattc aaggtggaga tattcttctg gatggtcagt ctatcgttga
    20941 aaataaaaaa gattttcacc tagttcgcca aaagattggc atggtctttc aaagttatga
    21001 actctttccc catctggatg tcttacaaaa cctcatccta ggccctatca aagctcaagg
    21061 aagggacaag aaagaagtaa cggaagaagc tttgcaatta ctagagcgtg tcggtttgct
    21121 ggataaacaa catagctttg cccgtcaatt atctggtgga cagaagcaac gtgttgcaat
    21181 tgtccgtgcc ctcctaatgc atccagaaat catccttttt gacgaggtga ctgcttcgct
    21241 ggatccagaa atggtgcgtg aggtgctgga acttatcaat gatttggccc aagaaggccg
    21301 taccatgatt ttagtaaccc acgaaatgca gtttgcccaa gccattgctg accagattat
    21361 cttcctcgac caagggaaaa tcgctgaaga aggaacagct caagccttct ttaccaatcc
    21421 gcaaaccaaa cgagcccagg aatttttaaa cgtctttgac tttagccaat tcggctcata
    21481 tctataaagg agattcttat gaaactattc aaaccactct taactgtttt agcacttgcc
    21541 tttgccctta tctttatcac tgcttgtagc tcaggtggaa acgctggttc atcctctgga
    21601 aaaacaactg ccaaagctcg cactatcgat gaaatcaaaa aaagcggtga actgcgaatc
    21661 gccgtgtttg gagataaaaa accgtttggc tacgttgaca atgatggttc ttaccaaggc
    21721 tacgctacga tattgaacta gggaaccaac tagctcaaga ccttggtgtc aaggttaaat
    21781 acatttcagt cgatgctgac aaccgtgcgg aatacttgat ttcaaacaag gtagatatta
    21841 ctcttgctaa ctttacagta actgacgaac gtaagaaaca agttgatttt gcccttccat
    21901 atatgaaagt ttctctgggt gtcgtatcac ctaagactgg tctcattaca gacgtcaaac
    21961 aacttgaagg taaaacctta attgtcacaa aaggaacgac tgctgagact tattttgaaa
    22021 agaatcatcc agaaatcaaa ctccaaaaat acgaccaata cagtgactct taccaagctc
    22081 ttcttgacgg acgtggagat gccttttcaa ctgacaatac ggaagttcta gcttgggcgc
    22141 ttgaaaataa aggatttgaa gtaggaatta cttccctcgg tgatcccgat accattgcgg
    22201 cagcagttca aaaaggcaac caagaattgc tagacttcat caataaagat attgaaaaat
    22261 taggcaagga aaacttcttc cacaaggcct atgaaaaaac acttcaccca acctacggtg
    22321 acgctgctaa agcagatgac ctggttgttg aaggtggcca ttaactctta aaagggactg
    22381 gattttaagc tccaatccct ttttaagatt ttacctataa catcctgagt ctatctaaga
    22441 tgttcaatct gaacacagtg tacatacttt atcttctatt gcatatactt tatcacataa
    22501 gatacgaata tcctcttcac tgtgactagc aatcaaaatt gttgtccctt tttcactaga
    22561 gagctttcta aacaatgttc tcatattttc tacacttgat ttatccaagg cattcatagg
    22621 ttcatctagt aaaagaatag agggattctc cataattgct tgagcaatcc ctagcttttt
    22681 cctcatacct agcgaataag ttttaacttt ctggtctttt tgctcatata gaccaactat
    22741 tttcagtgta tcattgattt cctgattacc aactactcct cgtatgcttg ccaaatattg
    22801 taaattctta aagccactat aataatttat aaaaccaggt tcttcaatca aagctcccaa
    22861 attagctgga atttttctct caggaacaat attttcccca ttgattaaca cttctccata
    22921 agacggacta tataaaccag ctattaattt aaacaataca cttttccctg agccattcgc
    22981 accagtaatt cctataattt ccccctgttt acaactaaaa ttaaggtttt gaaaaacaca
    23041 tgtttttttt aatttcaact caatattttt taatatgatt atttcattca ttctataaac
    23101 ctcctctttt gacgagtgaa atagaaaata cttttaaaaa gaaagactaa aaatagcaac
    23161 tgaagaaata aatctcgtcc tatatctcca ttccctcgat tcaaaatata aaatagataa
    23221 ttagttcgat ttcctacaaa tagaccacca aacacaatca tgagtaaaaa gaaactaacg
    23281 caagcaaagt tcatttgtac attcgctcct agtgcgtata acataaagca aaacaagact
    23341 aacacacaag cattcaaaga atcaactata aacaaaactc ctatatccca gtttggtaac
    23401 tgtaacataa attgaatcac tagaactttt accatgatta aaatgagtcc ataaagaaaa
    23461 caggtccaaa tctgatacct aatccagagc ttaatagaag aaaatcgaat cacttccata
    23521 aagaaatcgg atgctcttct acgatataca actgctagaa aaaatgtatg aataataaac
    23581 caatgaagca accatataga taagactaaa aaagagtttt gactcagatt aggccctttt
    23641 aaaatttcta taacaagtct atcatttcct tctaaccaat accataatcc taaacaaatc
    23701 aatatccaaa aaagaacata accccaaaag tacttggtat agattatctg attcaacctc
    23761 cacatgtgac tacttaactt tcccatttcc aacttttaca ctctcctcca gtttctatga
    23821 acagaaaata cagtcaatgg aattatgata gatagtaatg taagccaata aatcaatgca
    23881 tacggattgg aatttaccat atactgaaaa attggcaata atccaattat cccattgtcc
    23941 aactgataaa tccagaataa ggattctaca aataaaaaag taaacagaaa tactaagctc
    24001 atgtttgatt ttttaaacca agaaaaactg ctaatagtaa gtaaggataa aaagaaatag
    24061 tatgctatat aagagaaaaa aaatcctata aagaaactag cattgtttgc aatacttata
    24121 ccataaaatt ctcttaaaaa atcaacctcc tttatctcca aagagaagct aaaaccatta
    24181 ctaaatgcaa ttagaaaaat caataaaaat aaagtcgccg tccaaatccc cgtactaaga
    24241 gctgctaatt tgaaactaaa actggtaaag tgcttaattg atttcagacg aatgcgacac
    24301 tccaacctat taaaatagtt attcatcaaa taaaaaaaga acaatatata tgtgaacgga
    24361 aagcaatata ctccagtcgt catatcttga agtaaaacta agatccattc taatacattt
    24421 ggatggattg aatattggcg acagcgcaat aaatatactg tactagataa aacacaggat
    24481 agcagtaata taaaataaac caatactgct aagaaatctt ttttataaaa ttgaacaaat
    24541 tgtttcatta tacatagtcc tctgaatgta gaaaaaatgt accataaaca accaaacaac
    24601 taacaaataa aataaaagca agatgagcac taactaagga aagactgata tctttctgat
    24661 atcccaaagc tagcgttgtc acaggttcta agtaagatag ccctaaaata gcccataaaa
    24721 taccaccaac catcatatag gcaactggga tgaaaatagc tcctaatttt ttcttcacta
    24781 gcaaagcact agctagtcca aaaatagaga acacagcgcc ccaaactcca taccagagag
    24841 tcgtcacaag actatagagc aactgattgg aatcaaataa ttcttttaag gcaccactat
    24901 aatctccaat ataaatttcc tgataaggag tcactaaaag attaattcct aataataata
    24961 aataggggag aaaaaagact agaaaagaag aaataattgc agtactacct acaatagcta
    25021 gatacctctt tttagaaatt cggcacaatt gtgctgttag aaaatgactc tcagcatcct
    25081 ctattatctg actagaatag ggcagtgtac agataagtgc agctactagg ctaatcggtg
    25141 aaaatcctcg aatagaagaa gcggcaaaaa aaatcgataa accttcaatt ttataaatac
    25201 cattgaaagc aaggaaattt cctaaactca tgcaaagaag ggtcaaaaat aaagacatat
    25261 aaaatcgagg tgattgaacg actcgtacaa gattacaaat gaaaaattcc atccttactc
    25321 ctccttataa taaaaatagg gtgtagcatt cttttttcat gctacaccca caatcaacca
    25381 tctttaaggc ttactctgac aagtaagtta ataagaatct ggactccaag aacctgaagt
    25441 atgaattctt acatgatttc caaattgtgg cgccatagct aatctagtac cagaaccaat
    25501 ataattgtca ccacctccat tatagtacat gacaatccta gagccagacc ccaatgaata
    25561 taccggagta atatctgacc cactataggc gctacgaata gaggtattta atgttttacc
    25621 gccaccagta ctgtcattat tattaattcc agcagaggcg ttttctttct caagctcact
    25681 agttgtatcc gaaccccaac gtggcaacgt taaatcataa tctccaatct gtctagctaa
    25741 aactgtaggg agaaacaaac tagatgcaat tgtaactacg caaaaaaggg aatatatttt
    25801 tcttcttttc atgacatcgt cctcctaaga agtgataaat aagatagttg attgatcaat
    25861 ttgatacata ttatattttc attatatcaa caaaagaaag cgttgtcaat tattttgttt
    25921 aaaatattgt catattttaa acaaaatggt aaaagaggct cggtagcctc gtctctcttt
    25981 atcttactga cctaaccttc ttgccaattt tcttggtctt ctttaaagcg ttttagaaga
    26041 taaaggccct ctggcgtgat gtaaccttct tcttgggcta gatggataag atcgctatag
    26101 tttgaaagcg tcacaagttt aacaccagca tctgcaaagt tcttatctgc ttttggcaat
    26161 tggtagctga aaatcgctac aactccaagc acatctgctc cttctcgctt ggctgctgct
    26221 acagcttcaa gaactgaacc acccgttgaa ataaggtctt caaccactac cattttttga
    26281 ccttgagcta cgcgaccttc gatttgatta ccagctccgt ggtcttttgg tttgctacgg
    26341 atgtaggcaa aaggcaagtc catcttatca gcaataatgg ctccgtgtgg aatccctgct
    26401 gttgcagttc ctgcaatcac ttctacttca ggaaaggctt ctttgatagc ttccacaaaa
    26461 ccattttcaa ttagggtacg agtttctgga taggctagtg tcacacgatt atcagtgtaa
    26521 atcggtgact tgataccaga tgcccaagtg aagggttcct ctggtttgag gtaaacggct
    26581 tggattttca agaggtggct agcgatatct ttagcaagtg tcatggtatt ctccttttat
    26641 ttttctaatc tagttcttta attccagtcc tgtgtccatt catccttgat ggcatgataa
    26701 gctgcaacag gctcctcagc ttgggtaatg ggacgtccca ctacgatata gtcactgccg
    26761 atttgatagg catcagcagg tgtcatgact cgtttttgat ctccaactgc aacaccagct
    26821 ggacgaatcc ctggtgtcag acagataaaa tctggattgg tagcctgctt gatgacttgt
    26881 acttcctgag ccgagcaaac aacaccatcc aagccagctt cagctgtctt cttggcatag
    26941 tgaatcacag actcttgcag actggtttgg atattttgaa actcctgcat ctgagcttct
    27001 gacgttgatg tgagctgagt tacagcgatc aatttagctt gacttccaag accttcacgc
    27061 gcagccttca tcatctctac accaccagcc gcatgaacat tggtcatatc cacaccaagc
    27121 tgagatagga tcttcatggc tgacttgact gtattaggaa tgtcatgaag tttgagatcc
    27181 aaaaagacac tatgacccaa accttttaag taggacacaa tctcaggccc cgctgcgtaa
    27241 taaagctcca tccctacctt gagataaagg ctttcttctg ctgggaaaag agctaaaaat
    27301 tccttgaccg cctcaaaact aggaaaatca agagcaatga ttggacgatg ttctcgcata
    27361 ggtttctcct tttaccttta ctagtgagag agtctggcca acagaagcca cgaaaaaagg
    27421 aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc accgtctaac
    27481 cttagctgcc tctctggact gctttaaagg ttttttacta ttctattatt tctactagca
    27541 cttgtcaagt aaaaacatgg tcacgtatgt gttgactgct attgaacacc tcacaagact
    27601 ctttccaaaa gaatagttaa agactttcac ttaggacaga gaaaaagagt ttgcttgtta
    27661 ccctttaatt gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca
    27721 aaggggaagt aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg
    27781 gcaacaatta ccgaaaaaat ccttaatggt gctttgctag cttattaatc accgtcccca
    27841 aaaatacttg gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg
    27901 cattttttat tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag
    27961 cactattgtt atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc
    28021 tgtagaattg ctgtcaaaaa gatcagttca tttttccttc ccacttgtgt ttataatcat
    28081 taaaataact caattaagaa attttctttt tcctaatagt tatcgtaatt aaagttaata
    28141 gaagaacaat ccaaataagt agtgttagat taggaattag agtttcattc catgaaaatc
    28201 cctcccattt tgtgaaaaac ttagtaaaca gtcccataaa actataatct gttatcttcg
    28261 caactgtctt atccaaacca gatagcatcg gtaagaaagc aactaaaatc atagcaggaa
    28321 gactgataac ctgagctact acttggctct tcgcggttaa acctatcaat aaatagaata
    28381 aaatgatgga taaagaggtt agaagaacga ttgtaatata attaaaagta tgtacaattg
    28441 taactcctaa aataagagga gtagttccca taatcacaaa agttagcaaa aaaggaagaa
    28501 acatcgttga taaaatgtat tcggatcctt taacaccact caacagaaga gtttgtaaat
    28561 tgtacttttc tttttcttca gacaagataa tagttatagg acttccaaca gccaaagcca
    28621 aagaaaaagg taaacacatc atcaaaagaa ctaatgcctg ttgatcgttg accttcccct
    28681 gtgtttccat aagatattta taaaaatatg tgaaagcaaa aggcactaaa acttgcaata
    28741 aaatactctt attggaaagg ataatttgac aacgcaacca taccaaagcc agaaaccgtt
    28801 taagcattta gctttcctcc tgttaatgtg ataaaaatat cttctaaagt aggctcacat
    28861 gaatgaattg aaaaaatatt ttccagatca gcctgagata cctgttctag tgatgtaaaa
    28921 tcaaaagtta tctaattccc attataatct gtcaacttaa tctttttatc tttattatat
    28981 ctttgaatga gttcagaagg agctccttgc tcaactaatt tccctttatt taataaggca
    29041 acataatcac ataaaagagt tgcttcattc atatcatgag tcgttagaaa aatcgttgtc
    29101 cctgctgttt tcaattctaa aattaactca tgaattgttc gagaagttgt gggatctaga
    29161 cctgaggtcg gttcatccag aaagagtaca gcgggtttgt tgataagagc tcgtgctaaa
    29221 agcattcgtt gcctcattcc agtggataat tttcctgcta ccatcttgcg actatcatat
    29281 aatcctactc gctttaacaa attatcaaca cgtgatttac taatattata aaatttacta
    29341 taaaaaagaa gattgttata cagagacatt ttctcataaa atccacttgt atcgctaacc
    29401 aatccaattc tctttaattc accgcttgtt aaattttgag atttttgtcc caaaataata
    29461 gattgtcctt tatcggcaag gaactgccca gtcagaatat taatcgttgt ggtctttcca
    29521 gaaccagatg gtcctaaaaa tccaaaaatc taaccttctt taacagtgaa gcttatatta
    29581 tttaaagcta ttttatcacc aaaacttttt gataaatggc taacttcaat catactcatt
    29641 gcacctcctt tatattctac atttttactt aacatctatt tacttatctt tatcaaataa
    29701 acgtcttaaa aaaaacaata acattaagca tataaccgtt agcaagattg tttcaatatt
    29761 attgataata tgatacattc tcaagcagta taaaataatt atatatatgc aaatgctcat
    29821 tatacctatt tttttaaaca tactaagcct ccttgccaaa taataaagtt atataataac
    29881 taagacacac tatacctaac ataataaata tccacagcat taaaaatatt atcatacaaa
    29941 taaaaatatc cactggtaac tgaataaatg ttctaaaatt aacaagcaaa aataaaatct
    30001 caaacgatga aaaaagccat actatatttt ccaatgatgt ttgaatattt ttattgtagt
    30061 aagcataata tatagcaaaa ataataccca agaacaatac tattaattgt gttcctataa
    30121 cagtgaactg cccaatagca gataaaaaag ctactcctcc tgataataag caaaaacaaa
    30181 ctgaacgaat aaatgttttc gctctaatat tgttatcttt cactttatta ttttttttac
    30241 aaattggaca ttctccgttt tccagaacat atttttcttg acttagagca tgatttctca
    30301 tattataaac gtaagcgtta tctattagga tttcattata acatcccaga aatattttaa
    30361 ttattaaatt agtcattatc cctcccaaaa tagcaggcat ctctggtgta gtcggccact
    30421 ttgtcttatc agataaagtg tacttattta tatctttgtt tatattccga caaccaaagc
    30481 aagaaccgat ggtagggata tatatattat caataataag atagcatcca ttaaaccctc
    30541 ctgatatgta ggatatctta tgcgatacag caaattgatt gacaattttt ataatatcaa
    30601 tgggcgtatc aattgcttta acgataaaat ctatactccc atattccgca acaatttttt
    30661 ctaattcttc tactgaagaa actttaatag aaataggtac tacctgaaca tctgaattat
    30721 acttgtgtat tttttcagaa agaacattaa tcttctcctt accaacattc gactctgtat
    30781 aaagaatttg cctatttaaa tttgatggtt ctattatatc gtaatcagcg acaataagtt
    30841 tcctcactcc atacatactt agacttagag atatataaca tcctaaggct cctgctccta
    30901 atactaatac tgttttattc tgtattttat tatactcttc attataaaat aacgaatagt
    30961 aacctttagt tctagaatat ctactatcaa tatctatctc atccgaaatt aaaatttgtt
    31021 catttatagt tcaaatgtta gtttactgcc taatacttct tctatctcta atagttcctt
    31081 acaactatta aatagatcgt tgataaattc ttgcgaaatt tgaggttcta tagctatttc
    31141 ccgcatactc cgaccacgta aatacattat accttctttt ttataagcaa aaacataact
    31201 atttacgtag aacatatttc gtccttccta tcatatataa tatagaaagc agtatagaaa
    31261 caaccacccc tcctatacta cgaacaataa tattgggtgt caaaaactgt aatagttgac
    31321 tcaaagggaa ataaataata acaaatgcta ttaaaagttg aactatatat tgaaaattca
    31381 agttattatt gttagaattc aagtatctta aaataatacc actatcatac tgaaaaaaag
    31441 gaattgaatt aataaaaatc atacctaagt taatgataaa aaataagagt ccaagcaatt
    31501 tatacgatgt gaacaataaa acaagtaaac ctgtaagtga taaaatcgaa tttgaagcaa
    31561 ttcctgctaa cataattttc aaaaattgtt ttttattttt taggaattgc accccactta
    31621 aatctacaaa aaaagccaaa ttaaacaaaa gtagcattat tccacaattt gggatctcaa
    31681 tttgataatt attagcaatt attgcatgac taaattcatg tatcgttgca gatataataa
    31741 caacaagcaa ccaaaataaa agaatgttta gcgttattgg aaagttttgg aaattagtca
    31801 aaatatccgc
//
LOCUS       DBEJJE010000026        31449 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEJJE010000026 DBEJJE010000000
VERSION     DBEJJE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.26"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL3F5_001153"
     tRNA            5..75
                     /locus_tag="ACL3F5_001153"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="ACL3F5_001154"
     tRNA            110..183
                     /locus_tag="ACL3F5_001154"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="ACL3F5_001155"
     tRNA            266..355
                     /locus_tag="ACL3F5_001155"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="ACL3F5_001156"
     tRNA            366..439
                     /locus_tag="ACL3F5_001156"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="ACL3F5_001157"
     tRNA            443..515
                     /locus_tag="ACL3F5_001157"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="ACL3F5_001158"
     tRNA            528..608
                     /locus_tag="ACL3F5_001158"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="ACL3F5_001159"
     tRNA            613..683
                     /locus_tag="ACL3F5_001159"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="ACL3F5_001160"
     tRNA            698..770
                     /locus_tag="ACL3F5_001160"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="ACL3F5_001161"
     tRNA            781..852
                     /locus_tag="ACL3F5_001161"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="ACL3F5_001162"
     tRNA            862..945
                     /locus_tag="ACL3F5_001162"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="ACL3F5_001163"
     CDS             1052..2329
                     /locus_tag="ACL3F5_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0514972.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETMIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /gene="thrC"
                     /locus_tag="ACL3F5_001164"
     CDS             2405..3889
                     /gene="thrC"
                     /locus_tag="ACL3F5_001164"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0514973.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="ACL3F5_001165"
     CDS             3950..5230
                     /locus_tag="ACL3F5_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0514974.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="ACL3F5_001166"
     CDS             5234..5854
                     /locus_tag="ACL3F5_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0514975.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7162
                     /locus_tag="ACL3F5_001167"
     CDS             6020..7162
                     /locus_tag="ACL3F5_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0514976.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7482..7906
                     /locus_tag="ACL3F5_001168"
                     /pseudo
     CDS             7482..7906
                     /locus_tag="ACL3F5_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            7917..8275
                     /locus_tag="ACL3F5_001169"
                     /pseudo
     CDS             7917..8275
                     /locus_tag="ACL3F5_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8382..9000
                     /locus_tag="ACL3F5_001170"
                     /pseudo
     CDS             8382..9000
                     /locus_tag="ACL3F5_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9028..9885)
                     /locus_tag="ACL3F5_001171"
     CDS             complement(9028..9885)
                     /locus_tag="ACL3F5_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0514977.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10015..11157
                     /gene="tgt"
                     /locus_tag="ACL3F5_001172"
     CDS             10015..11157
                     /gene="tgt"
                     /locus_tag="ACL3F5_001172"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0514978.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11258..13075
                     /locus_tag="ACL3F5_001173"
     CDS             11258..13075
                     /locus_tag="ACL3F5_001173"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0514979.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13228..14379
                     /gene="nagA"
                     /locus_tag="ACL3F5_001174"
     CDS             13228..14379
                     /gene="nagA"
                     /locus_tag="ACL3F5_001174"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0514980.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPYTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14542..15600
                     /locus_tag="ACL3F5_001175"
     CDS             14542..15600
                     /locus_tag="ACL3F5_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0514981.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15751..16116
                     /locus_tag="ACL3F5_001176"
     CDS             15751..16116
                     /locus_tag="ACL3F5_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0514982.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16192..17133
                     /gene="comGA"
                     /locus_tag="ACL3F5_001177"
     CDS             16192..17133
                     /gene="comGA"
                     /locus_tag="ACL3F5_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0514983.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEEFAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17081..18097
                     /gene="comGB"
                     /locus_tag="ACL3F5_001178"
     CDS             17081..18097
                     /gene="comGB"
                     /locus_tag="ACL3F5_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0514984.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMIVFVSVGVLLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLRPMYQNM
                     EVNF"
     gene            18099..18425
                     /gene="comGC"
                     /locus_tag="ACL3F5_001179"
     CDS             18099..18425
                     /gene="comGC"
                     /locus_tag="ACL3F5_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR0514985.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18418..18822
                     /gene="comGD"
                     /locus_tag="ACL3F5_001180"
     CDS             18418..18822
                     /gene="comGD"
                     /locus_tag="ACL3F5_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0514986.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18785..19087
                     /gene="comGE"
                     /locus_tag="ACL3F5_001181"
     CDS             18785..19087
                     /gene="comGE"
                     /locus_tag="ACL3F5_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0514987.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19050..19511
                     /gene="comGF"
                     /locus_tag="ACL3F5_001182"
     CDS             19050..19511
                     /gene="comGF"
                     /locus_tag="ACL3F5_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0514988.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWILFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19489..19902
                     /gene="comGG"
                     /locus_tag="ACL3F5_001183"
     CDS             19489..19902
                     /gene="comGG"
                     /locus_tag="ACL3F5_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0514989.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20039..20633
                     /locus_tag="ACL3F5_001184"
                     /pseudo
     CDS             20039..20633
                     /locus_tag="ACL3F5_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20694..21647
                     /locus_tag="ACL3F5_001185"
     CDS             20694..21647
                     /locus_tag="ACL3F5_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0514990.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21698..22888
                     /locus_tag="ACL3F5_001186"
     CDS             21698..22888
                     /locus_tag="ACL3F5_001186"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0514991.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22889..23020
                     /locus_tag="ACL3F5_001187"
     CDS             22889..23020
                     /locus_tag="ACL3F5_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0514992.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            23037..23408
                     /gene="rnpA"
                     /locus_tag="ACL3F5_001188"
     CDS             23037..23408
                     /gene="rnpA"
                     /locus_tag="ACL3F5_001188"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0514993.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23383..24207
                     /locus_tag="ACL3F5_001189"
     CDS             23383..24207
                     /locus_tag="ACL3F5_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0514994.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24226..25212
                     /gene="jag"
                     /locus_tag="ACL3F5_001190"
     CDS             24226..25212
                     /gene="jag"
                     /locus_tag="ACL3F5_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0514995.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25263..25886
                     /locus_tag="ACL3F5_001191"
     CDS             25263..25886
                     /locus_tag="ACL3F5_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0514996.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26017..27474
                     /locus_tag="ACL3F5_001192"
     CDS             26017..27474
                     /locus_tag="ACL3F5_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0514997.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27497..27778
                     /locus_tag="ACL3F5_001193"
     CDS             27497..27778
                     /locus_tag="ACL3F5_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0514998.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27855..28340
                     /locus_tag="ACL3F5_001194"
     CDS             27855..28340
                     /locus_tag="ACL3F5_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0514999.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28357..29022
                     /locus_tag="ACL3F5_001195"
     CDS             28357..29022
                     /locus_tag="ACL3F5_001195"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0515000.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29026..29889
                     /locus_tag="ACL3F5_001196"
     CDS             29026..29889
                     /locus_tag="ACL3F5_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0515001.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29891..30595
                     /locus_tag="ACL3F5_001197"
     CDS             29891..30595
                     /locus_tag="ACL3F5_001197"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0515002.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30772..>31449
                     /locus_tag="ACL3F5_001198"
     CDS             30772..>31449
                     /locus_tag="ACL3F5_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGR0515003.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEIT"
BASE COUNT         9396 a         5532 c         7247 g         9274 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttatgaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgagttttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaagc
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgcctgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattatttc ccctcaagag aaggattttg aaactcatcg
     1981 tagttaccaa taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactatgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta cttatccaaa
     2521 ggtagatttg gactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagc tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcactatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatatt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaagga tggtgtcagc aagattcaag agttacaaat
     2941 gaccactcag actggcgaca atactcatgt tattgctatt gatggtaact ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga tgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaattggt ttgccagttg gtaaattgat ctgtgcttca aatgacaaca atgttttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacagctg aactcatgaa tgctttgaac atgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttctggagct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacagcggca gaaatcaagc gtgtttatga gttagattct tatattgagg atccacatac
     3601 ggcggttgcc tcagcagttt atagaaaata ccaagcggtt actgatgatg cgactaagac
     3661 agtgattgct tcaacagcta gtccctacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga gacagctcct gttcgtcaca agacaactgt
     3841 agcggctgct gatatgcaag cagcggttga ggcttattta ggactttaag atagagggag
     3901 taaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagtct
     4381 gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttctgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agccaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttgggacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaaaatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaaa aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaacct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac aggtactcat
     6001 ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgataccttg agcactattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacag aagttgaaat ccaaacacct caagcagact ctagtgaaga
     6361 agtgacaact gcgacagcag atttgaccac taatcaagtg accgttgatg atcaaactgt
     6421 tcaggttgca gacctttctc aaccaattgc agaagctcca aaagaagtag catcaagttc
     6481 agaagttaca aagacagtga ttgcttctga agaagtggca ccatctacgg gcacttctgt
     6541 cccagaggag caaacggccg aaacaagcag tgcagttgca gaagaagctc ctcaggaaac
     6601 gactccaggt gagaagcagg aaacacaagc aagccctcaa gcagcatcag cagtggaagc
     6661 aactacaaca agttcagaag caaaagaagt agcatcatca aatggagcta cagcagcagt
     6721 ttctacttat caaccagaag agacgaaaat aatttcaaca acttacgagg ctccagctgc
     6781 gcccgattat gctggacttg cagtagcaaa atctgaaaat gcaggtcttc aaccacaaac
     6841 agctgccttt aaagaagaaa ttgctaactt gtttggcatt acatccttta gtggttatcg
     6901 tccaggagac agtggagatc acggaaaagg tttggctatc gattttatgg taccagaaag
     6961 ttcagaatta ggggataaga ttgcggaata tgctattcaa aacatggcca gccgtggcat
     7021 tagttacatc atctggaaac aacgtttcta tgctccattc gatagcaaat atgggccagc
     7081 taacacttgg aatccaatgc cagaccgtgg tagtgtgaca gaaaatcact atgaccacgt
     7141 tcacgtttca atgaatggat aaacccgact tggtaacatc attttgacga atgagatcta
     7201 gctttcgtga taggaagcga ttctcgttcg ttttttcttt gtcatactct tcgaaaatct
     7261 cttcaaacca cgtcagtttt atctgaaacc tcaaagctgt gctttgagca acctgcgact
     7321 agctttctag tttactcttt gattttcatt gagtatcaat ttgaatggaa aatggaaagt
     7381 tattatcttg taataatcca agcaacattc ttgcaatcta ttttacttta tatcacaatt
     7441 gattggtcaa ctattgataa gtcaatggat aggaggaaga aatgatagag attcaagatt
     7501 tactgtatca actccgcttg tctgagcaag cgagtacgca attgtttgaa aaaggcttgg
     7561 gattagtttg acacggtatc agattttact gtttttgctg gagcattctc cttgtaacca
     7621 aatggcggtt caggagcgtt tgaaaattga tcaggctgct ttgacacggc atttcaagat
     7681 tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc gggaagtgtt
     7741 ggtagaggct gcgaagtatg ccaaggagca gttagtggtg aatccccctc tgcaacatat
     7801 caaggttaag gaagagatgg aaagtatctt aacagagttt gagagaacag aactcagccg
     7861 tttattaaat aaattggttt tgggtattga aaatatagaa atttaaggag aaatagatgt
     7921 caattatttt aacaacgatc gttgctttgg agcattttta tattttttat ttggaaagta
     7981 ttgccacgca atcagatgcg actagtcgtg tatttaatat ggaaaaggaa gaattggctc
     8041 atccgtcagt aagttcattg ttcaaaaatc aaggaattta taaggctctg ctaggagtct
     8101 ttctcttgta tgtcatttat ttctcacaga atttagaaat tgtgactatt tttgtcttat
     8161 ttgtgattgg tgctgcgact tacggctctt taacagcgga taaaaaatta ttttgaagca
     8221 aggtggatca gctattttgg ccttgattag tattttactc tttaaataca cttgaaggtt
     8281 gattctaatc tcgctaatcc tttttaatcc agaataaggg aaatatgtta tacttgtttt
     8341 taagaaaaaa gtctcattga attggttttg aggagttaga aatgaaagta ttagtgacag
     8401 gttttgagcc cttttgaggc cattaaaggt ttaccagctg aaatccatgg tgctgaggtc
     8461 cgttggctag aggtgccgac agtttttcac aaatctgctc aagtattgga agaagagatg
     8521 aatcgttatc aacctgactt tgtcctttgt attgggcaag ctggtggaag aactagtttg
     8581 acacctgaac gagtggccat taatcaagac gatgcacgta cttctgataa cgaagataat
     8641 caaccgattg accgtcccat tcgcccagat ggtgcttcgg cctactttag tagtttgccg
     8701 attaaagcga tggttcaagc tataaaaaaa gagggcttac cggcctctgt ttccaatacg
     8761 gcagggactt ttgtctgcag ccatttgatg tatcaggctc tctatttggt agaaaagaaa
     8821 ttttcatatg ttaaggcagg ttttatgcat attccttata tgatggaaca ggtggtgaac
     8881 agaccgacta ctccagctat gagtttagtg gatattcggc gagggataga agcagcaatc
     8941 ggcgctatga tagaacatgg agatcaggaa ctcaagttgg taggcggaga aactcattga
     9001 tagaaaaaag cttgagggga aaaaccttca agcttttgga cgttttcgag ccaatactgc
     9061 tcggtaaaac ataattttag tgcattggat ataaggtagg agtgaaaaac tagcaatgcc
     9121 aaaggtaatc caattgagga agtaccaagg aagaagctgt aaatctagga caaagtgctg
     9181 gaacttgtag cccttcataa aggaacggct agtttttagg attcgtcttg gtgggacctg
     9241 tcctaggtct agactataac agagaagaaa ttccacctgt gaataggcat aatactgtgg
     9301 aatatagagg atatttccta caatgatcaa gatgagactt gcaagaaagt agagtccaaa
     9361 gaccatgagg aaacgctcgg tttcaactga tgagagatct agatttggaa actcaggatg
     9421 tagggtgacg aattttttgg ctaaaaagct actataaaag aggaggtaaa tcccaagtaa
     9481 attagggata ctccataaaa agagatagaa acgtttgaga agtagggtca aaaaggtttg
     9541 agaaaagcgc tcctcatcaa agagagctag gctgtttttt acagatggct ccgttttaga
     9601 atctttcatg agtgtcagtg ttgcatagac ggaactggtc aaaagaatag tcccgataaa
     9661 ggagactagt agaggaaaga ggtaggcttg aagtatttgg ccaagtatgc tgaaaaatgg
     9721 ctgttctaaa acagtcccgt ggatccgaga taagggatta agaaaactag ataagatgac
     9781 cagcatactg ggaaggatat agaggagaaa gagacggggg gtgtcagcct gaaaatgttt
     9841 tgactcctga cgaattgttt ttaaatcaat ttttggatag ttcattctct tattatacca
     9901 tagttcttat acatagttcg tgacagttcc tacttttttt gataaaatca tacagtgtgt
     9961 ccttgggcac actgtatgaa ctgggactgt ctttcccagc ttcggaggta aaaaatgtca
    10021 gattcaccaa tcaaatatcg tttgattaag aaagaaaaac acacaggagc tcgtctagga
    10081 gaaatcatca ctccccacgg tacctttccg acacctatgt ttatgccagt tgggacacaa
    10141 gccactgtca aaactcagtc acctgaagaa ttgaaggaga tgggttcggg aattatccta
    10201 tcaaacacct atcatctctg gcttcgccct ggagatgaac tcattgcacg cgctggtggt
    10261 ctccacaagt tcatgaattg ggaccagcct atcttgacag atagtggtgg ttttcaggtt
    10321 tattctttag cagatagccg taatatcaca gaagaaggag taacctttaa aaatcatcta
    10381 aatggttcta agatgttcct atccccagaa aaagccatct ctattcagaa taatctgggt
    10441 tcagacatca tgatgtcctt tgatgaatgt cctcagtttt atcaacctta tgactacgtt
    10501 aagaaatcga tcgagcgtac cagccgttgg gctgagcgtg gtttgaaggc tcaccgtcgt
    10561 ccacatgacc aaggtttgtt tggaattgtg caaggtgcag gatttgaaga ccttcgccgc
    10621 caatcagctc atgatcttgt cagcatggat ttctcaggct actctatcgg tggtttggca
    10681 gtgggagaaa cccatgaaga gatgaatgcg gtcttggact ttacaactca actgctacct
    10741 gaaaataaac ctcgttatct gatgggtgtg ggagcgccag atagcttgat cgatggggtc
    10801 attcgtgggg tggatatgtt tgactgtgtc ttaccgactc gaattgctcg taacgggact
    10861 tgtatgacca gtcaaggacg tttggttgtg aaaaatgccc agtttgctga ggactttacg
    10921 ccactggatc ctgagtgtga ttgttacaca tgtaataact atacacgcgc ttaccttcgt
    10981 cacctgctca aggctgatga aacctttggt atccgcttga ctagctacca caatctttac
    11041 ttcttgctta acttgatgaa gcaagtgcga caagccatca tggatgacaa tctcttggaa
    11101 ttccgtgagt attttgtgga aaaatatggc tataataagt caggacgtaa tttctaaaat
    11161 ggaattgata taagctaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    11221 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    11281 gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    11341 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    11401 actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt ttagaagacg
    11461 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    11521 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg tcttaggctt
    11581 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    11641 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    11701 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatggtctt
    11761 tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    11821 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    11881 gggaagtatg ttagcaacta ttgtaggtgt tcgtcagacg acttccctcg tcaagcagtt
    11941 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    12001 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    12061 gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    12121 acatcatata caggagccga agattatcag ctttttagcg gatactagct atgcggttta
    12181 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    12241 attactgact ctgatttgtt cttatggctt tgccagtctg tcattttatg tattggaacc
    12301 ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc cttatattca
    12361 cgcaattctt gcagcaggta caggaatctt gacattcatt gtctgcatgg tgaccttgtt
    12421 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    12481 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    12541 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    12601 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    12661 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    12721 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    12781 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    12841 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    12901 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg caggaacaga
    12961 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    13021 tacgattgcc acagctttgc agacagctca agataagccg gttaaatcaa aataacttgt
    13081 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    13141 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgtag
    13201 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    13261 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    13321 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    13381 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    13441 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    13501 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    13561 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    13621 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    13681 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    13741 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    13801 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    13861 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    13921 ggagccatgt accaattgcc atatacctat gcagagttga tctgtgatgg tcaccacgta
    13981 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    14041 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    14101 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    14161 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    14221 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    14281 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    14341 gcaacctacc tagatggtgt gaaacgttat caagcataag agagaaggca gaagttagag
    14401 actagcttct gcttttttat acagggtact ttactggtaa ataaaaagtt aaaaaaatca
    14461 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    14521 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    14581 tttgttgatg tagacaaacc agttattcgc aagccaacag atgctattgt gcgtattgta
    14641 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    14701 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    14761 tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    14821 tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg gattttcggt
    14881 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    14941 taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    15001 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag cgtagccatt
    15061 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    15121 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    15181 actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta tgatttgaca
    15241 gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac atttgatttc
    15301 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    15361 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    15421 tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat tgaaccagaa
    15481 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctatga agtcttcagt
    15541 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    15601 gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc agatggctgg
    15661 attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc ggaattggtt
    15721 ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat gtacggagat
    15781 tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag tagaaaattt
    15841 gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt ggaacaagaa
    15901 tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc ggaagaccaa
    15961 cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc tcttttgcag
    16021 gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag
    16081 gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt tttggagttg
    16141 ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag tatggttcaa
    16201 gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga catttatttt
    16261 gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg ctgtaaaatt
    16321 ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt tgtggcgggt
    16381 atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc ctatgaccag
    16441 aagatagcgt ctctacgttt atctactgta ggcgattatc gggggcatga gagtttggtt
    16501 atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga tattgaagaa
    16561 ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt tgggagtggt
    16621 aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca agttatgtcc
    16681 atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt gaacgaagca
    16741 atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc agatctcttg
    16801 attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc tagtttgaca
    16861 ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta tgagcgtctg
    16921 ctggagttgg gtgtgagtga agaagaattt gcagttgttc tgcaaggagt ctgctaccag
    16981 agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca agaacaccaa
    17041 gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat cacaagtctt
    17101 caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca ccctatttaa
    17161 caatctcttt tctagcggtt ttcatctggt ggagaccatc tcctttttag ataggagtgc
    17221 tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg ggaaatcatt
    17281 ctcagaaatg atggaaagtt tgggatgttc aagtgctatt gtcactcagt tatccctagc
    17341 tgaagtccat ggcaatctcc acctgagttt gggaaagata gaagagtatc tagacaatct
    17401 ggccaaggtc aagaaaaaat taattgaagt agcgacctat cctttgattt tgctgttttt
    17461 tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg atagtagcaa
    17521 tattgccacc caaattatcg gtaatctgcc acaaatcttt ctaggaatga tagtttttgt
    17581 ttcagtaggt gtccttttag cactcacttt ttataaaaga agttctaaga tgcgcgtctt
    17641 ttctatctta gcgcgccttc cttttattgg aatctttgtg cagacctatt tgacagccta
    17701 ttatgcacgt gaatggggga atatgatttc acagggaatg gagttgacgc agatttttca
    17761 aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc tggctcaaac
    17821 cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct ttaggaagga
    17881 attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg agttggaaat
    17941 ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca tgaatttggt
    18001 gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg cggcaatgct
    18061 caggcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg atgacattct
    18121 tgaaaaaagc taaggttaaa gcttttacat tggtggaaat gttggtggtc ttgctgatta
    18181 tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg
    18241 acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt tatagcttgg
    18301 aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc acggaagaac
    18361 aggttaaagc ttataaagaa tacaatgata aaaatggagg agcaaatcgt aaagtcaatg
    18421 attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag tatccttgcc
    18481 ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca gattttcttt
    18541 atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag tcagcaaaag
    18601 actagtctga acttagatgg gcagacgatt agcaatggca gtcaaaagtt gccagtccct
    18661 aaaggaattc aggtcccatc aggccaaagt attacatttg accgtgctgg gggcaattcg
    18721 tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca attatatcta
    18781 ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga ttttactgga
    18841 agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg gacaaattca
    18901 aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa
    18961 gatggccttg cagacaggtc aaaatcaggt aaacataaac ggagttgaga ttcaggtgtt
    19021 ttctagcgaa aagggattgg aggtctacca tggttcagaa cagttgttgg caatcaaaga
    19081 gccataaggt caaggctttt accttgttag aatccctgct tgccctgctt gtcatcagtg
    19141 ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt cgctaccagc
    19201 aacaaagcga gcaaaaggag tggattttgt ttgtggacca acttgaggca gaattagacc
    19261 gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat ggcaaggaca
    19321 tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt ggacgggggt
    19381 atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat caactggttc
    19441 attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt gtggaaaaag
    19501 aagaaagtta aggcaggtgt tctcctctat gcagtcacca tggcagctat ctttagtctt
    19561 ttgttgcaat tttacttgaa ccgacaagtc gcccactatc aagactatgc tttgaataaa
    19621 gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga gcaagaaagt
    19681 ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac aagcttggtg
    19741 acgactgttc gtacggataa gagtcaatat gagtttctgt ttccttcagt caaaatcaaa
    19801 gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa agtggagaag
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ttaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgatttc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag ccgagaaaca gattgatctt ctatcagaca aagaaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta acccctagcc aagcaggcta
    20221 agtcagtcac tcttgtagac atttctgaga aaatgttgga gcaagctcgt ttgaaagtgg
    20281 agcagcaagc aatcaagaat atccagtttt tggagcaaga tttaccgaaa aatcccttgg
    20341 agaaagagtt tgattgcctt gctgttagtc gggttcttca tcatatgcct gatttggatg
    20401 cggctctctc actgtttcat caacatttga aggaagatgg gaaactcatc attgctgatt
    20461 ttaccaagac agaagctaat catcatggat ttgatttagc tgaactggaa aacaagctaa
    20521 ttgagcatgg tttttcatct gtgcatagtc agattctcta tagcgctgaa gacctgtttc
    20581 aaggaaatca ctcagaattc tttttaatag tagcccaaaa atcactcgcc tagtcaggga
    20641 gtgatttttc tataagaatg gaaaaaagaa gggaaatttg ataagatagg aatatggatt
    20701 ttgaaaaaat tgaacaagct tatacctatt tactagagaa tgtccaagtc atccaaagtg
    20761 atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat ctggatggtg
    20821 agactgagct agaacaggtc aaagacaaca atcagaccct taagcgttta gcactacgca
    20881 aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctgggcaa acagaaccct
    20941 tgcaggccaa tcaccagttt acaccggatg ctattgcttt acttttggtg tttattgtgg
    21001 aagagctgtt taaagaggag gaaattacta tcctcgaaat gggttctggg atgggaattt
    21061 tgggcgctac tttcttgacc tcgcttacta aaaaggtgga ttatttggga atggaagtgg
    21121 atgatttgct gattgatttg gcagctagca tggcagatgt aattggtttg caggctggct
    21181 ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagtgatgtg gtcatcagcg
    21241 acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa gttgcttcta
    21301 gtcaagaaca tacttacgcc catcacttgc tcatggaaca aggacttaag tacctcaagt
    21361 cagacggata cgctattttt ctagctccga gtgatttgtt gaccagtcct caaagtaatt
    21421 tgttgaaagt ctggttgaaa gaggaggcaa gtctggttgc tatgattagt ttacctgaaa
    21481 atctctttgc taatgctaaa caatctaaga ctatttttat cctacagaag aaaagtgaaa
    21541 tagcagtaga gccttttgtt tatccacttg ctagcttgca agatgcaagt gttttaatga
    21601 aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat agattttgtt
    21661 ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa ttgcaatcaa
    21721 tgcaggaagt tcaagcttaa aatggcaatt atacttaatg ccagaagaaa aagtattggc
    21781 gaaaggcttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa aatttgacgg
    21841 ccgttctgaa caacaaattt tggatatcga aaatcataca caagccgtta aaattttatt
    21901 ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag gtgttggcca
    21961 ccgtgttgta gcaggtggag aatatttcaa agaatcaaca gttgttgagg gagatgtttt
    22021 agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcca atgcagcagg
    22081 tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt ttgatacttc
    22141 cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa aatattacac
    22201 agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg tagcaggaga
    22261 agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct gtcatattgg
    22321 taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt ctatggggtt
    22381 cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc cagctatcat
    22441 tccttattta atgcaatata cagaggattt taacacacca gaagatatca gtcgtgttct
    22501 taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc gcgatataga
    22561 agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt atgttgaccg
    22621 tatccaaaaa catatcggtc agtaccttgc agtgctaaat ggagcagatg ccattgtttt
    22681 cacagcaggt gtcggtgaaa atgcagagag tttccgtcgt gatgtaatct cagggatttc
    22741 gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag gagacatctc
    22801 aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat tagtcattgc
    22861 ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa tacaaggagt
    22921 tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc ttgctatgat
    22981 tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt tgagttttga
    23041 agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag gaggggacaa
    23101 gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaac cattttcgag
    23161 taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa attaagcgac
    23221 ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc gactttgttg
    23281 tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa aatctactcc
    23341 atgtattaaa attatcaaag atttaccggg aaggaaatgg gagtgaaaaa gaaactaaag
    23401 ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcgac taatggggta
    23461 actagcgata ttacagccga atcggctgat ttttggagta aattggttta cttctttgcg
    23521 gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat tctctttacg
    23581 gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc ttctaggaaa
    23641 atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg tcgagatatg
    23701 gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat gggtgtcaga
    23761 cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc cctgttccaa
    23821 gccctatcaa gagttgactt tttaaagaca ggtcatttct tatggattaa ccttggtagt
    23881 gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt aagtacttgg
    23941 ttgtccaaca aagctttgtc tgagcgaaat ggcgctacga ctgcgatgat gtatgggatt
    24001 ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct atactggaca
    24061 gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt caagattatc
    24121 gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa aagaaaagcc
    24181 aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt agtatttaca
    24241 ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat tccaagaatg
    24301 aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct atttggtaaa
    24361 aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa agcaaatcaa
    24421 caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt gaagacggtt
    24481 agtgaagaaa ccgttgacct tggtcatgtg gttgatgcta ttaaaaaaat agaggaagaa
    24541 ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag acatgccagc
    24601 actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat cgaggaagcg
    24661 atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac tgaaaatcaa
    24721 gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca ggtggctacg
    24781 gatgtgactg cttatgttca aacgattatt gatgacatgg atgttgaggc tacactttca
    24841 aatgattata accgtcgtag catcaatttg caaattgata ctaacgaacc aggtcgtatt
    24901 atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa ttatctttac
    24961 aactgctatt caagaacctt ctatatcact attaatgtca atgattatgt tgaacaccgt
    25021 gcagaagtct tgcagaccta tgcgcaaaaa ttggcgattc gtgttttaga agaagggcgc
    25081 agtcatcaaa cagatccaat gtcgaatagt gaacgcaaga ttatccaccg tattatttca
    25141 cgtatggatg gcgtgaccag ttactctgaa ggtgatgagc caaatcgcta tgtcgttgta
    25201 gatacagaat aagtaaaatc agggttgacc tgattttttg ctagctagag gaggttaaac
    25261 tgatgttgaa taagataaga gactatctag acttttctgg tttgcagtac cgtagtcctg
    25321 ataaagcggg agcagagcga gagaagatgc tggcgttccg ccacaaagga caagaggccc
    25381 gaaaggcttt tacagaactg gccaaagcct ttcaagcaag ccatccagaa tggcaactcc
    25441 aacagactag tcagtggatg aatcaggccc agcgtttgag accacatttt tgggtttatc
    25501 tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat gggacatcta
    25561 ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat gagcaaacac
    25621 tgggcaagca gaccaaagtt ttagacattc caaccgttaa agggatttat tatctaacct
    25681 actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt actttacgcg
    25741 agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt cctatgacag
    25801 aaaattcgtc tgaagaagag atcgtagaag gcttattgaa gtcttattct aaaattcttc
    25861 cctattatct agctacgaga aaataagata atttgtaaaa catcataaat catacagtcc
    25921 aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc gcattatata
    25981 ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc aagtgttcta
    26041 aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt attggtgttg
    26101 ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt tgttaaagca
    26161 acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac ctttcgtcca
    26221 atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga cccttacttt
    26281 ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt tggaactgca
    26341 actacagctc tattgattgg ttttggaata aatatcttgc tcgtagctct tcgaaagatt
    26401 acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc tgcaacagta
    26461 tctcttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac agcagcgatt
    26521 ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga ggcaactcaa
    26581 cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc aatctggttt
    26641 gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa tcttaaatta
    26701 cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt gatgctcgta
    26761 ttcttcggag ccattctttt aatcttgggt ccagacatta tgtctaataa agaagtcatc
    26821 acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat tatccaaaca
    26881 gcttttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat gttcgtatct
    26941 gagttgacaa acgccttcca aggtatttca aacaaattgt taccaggttc attcccagcg
    27001 gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcctgtc aggatttata
    27061 tttggtttga ttggtcaatt gattacaatt gttttactca tcgtctttaa aaatccgatt
    27121 cttattatta caggatttgt accagtgttc tttgacaatg cagccattgc ggtctacgct
    27181 gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg tgtccttcaa
    27241 gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg tggctaccat
    27301 ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa ataccttggt
    27361 attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact tcaatttgcc
    27421 aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc ttagtatcta
    27481 gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa tgggttcatc
    27541 aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa cagattttac
    27601 agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg acatcgtaat
    27661 cgcttctctt catttgattc aagaattgga agggcgaact aatgggaagt taattgggct
    27721 tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac tacagtaaaa
    27781 ggttggaggg ggctggacag aaactgagag ttatcgtttc tgtccttctc cctctttaaa
    27841 taaaggaggc agatatgaat ttaaaacaag ctttaattga caacgactcg atccgactag
    27901 gtttagaggc taacgattgg aaagaagcag tcaaggtagc agtagatccc ttgattgaaa
    27961 gtggggcaat tttgccagag tattacgatg ctatcattga atcgactgaa gagtatgggc
    28021 cttactatat cttgatgcca ggtatggcta tgccccacgc tagacctgaa gctggtgtgc
    28081 aaagtgatgc cttttcatta attaccttac aaaatcctgt tgtattttca gatgggaaag
    28141 aggtatctgt tttgttggca ctagcagcaa caagttcaaa aattcacaca agtgtagcca
    28201 ttccacaaat tattgccctg tttgaattag aagattctat tgcacgttta caggcttgcc
    28261 agactaaaga agatgtcttg gctatgattg aagaatctaa ggatagccct tatctcgaag
    28321 gattggattt ggaaagttag aaagaggaat aaagaaatga caaaaagaat acctaattta
    28381 caagttgcat tagaccattc agacttgcaa ggagcgatta aagcagctgt ttctgttggt
    28441 caggaagtag atattatcga agctggaact gtttgcttgc ttcaagttgg aagtgaactg
    28501 gctgaagtct tgcgtagcct tttcccagat aagattattg tggcagacac aaaatgtgct
    28561 gatgctggtg gaacagttgc taaaaataat gcggttcgtg gagcagactg gatgacttgt
    28621 atctgttgtg caaccatccc tactatggaa gcagctctaa aggctatcaa gactgaacga
    28681 ggagaacgag gcgaaatcca gatcgagctt tatggcgatt ggacttttga acaagctcag
    28741 ctttggctag atgcaggtat ctcacaagct atttatcacc aatctcgtga tgctcttctt
    28801 gctggtgaaa cttggggtga aaaagacctt aataaggtta aaaaactcat tgacatgggc
    28861 ttccgtgtat ctgtaacagg tggtctagat gtagatactc tcaaactctt tgaaggtgtt
    28921 gatgtcttta cctttatcgc aggtcgtgga attacagagg ctgtggatcc agcaggagca
    28981 gcgcgtgcct tcaaggatga aatcaaacga atttgggggt aaatcatggt acgtccaatt
    29041 ggaatttatg aaaaggcaac cccaacacac tttacttggc tagaacgttt aaattttgcc
    29101 aaggagttag gctttgattt tatcgagatg tctattgacg aacgtgacga gcgtttagca
    29161 agacttgact ggagtaagga agaacgcttg gaagttgtca aagaaatcta tgaaactggt
    29221 gttcgtattc cttctatctg tttttcaggc catcgtcgct acccattggg atcaaaagat
    29281 tcagttctag aggaaaaatc tctagaactc atgaaaaaat gtatcgaatt agctcaagac
    29341 ttgggagttc gtacaattca attagctggt tacgatgttt actatgagga aaagtcaccc
    29401 cagacacgcc aacgttttat caaaaatttg agaaaagcct gtgactgggc tgaagaagct
    29461 caggtggtac ttgctattga aattatggat gatcctttca tcaatagcat cgaaaaatat
    29521 ttggctatag aaaaagagat tgactctccc ttcctctttg tatatccaga tattggtaat
    29581 gtgtctgcat ggcataatga tatctatagt gagttttatc ttggtcatca tgccatcgca
    29641 gctctccatc tcaaggatac ttatgcagtg acagaaagtt caaagggcca gttccgagat
    29701 gtacctttcg ggcaaggttg tgtcaaatgg gaagaagctt tcgatatttt aaaggaaacc
    29761 aattataatg gacctttcct aatcgaaatg tggtctgaaa attgtgaaac agtagaagaa
    29821 acacgcgcag ccattcaaga ggcgcaagct tttctctatc cactcattaa gaaagcaggt
    29881 ttgatgtaag atgaatcaag taatcaatgc tatgcgtaaa cgagtctgtg atgccaatca
    29941 atcattgcca aaacatggac ttgtcaaatt tacctggggg aatgtatctg aagtcaatcg
    30001 cgaactcggt gtcattgtta tcaaaccatc aggcgtggat tatgacgaat tgacacctga
    30061 aaacatggta gtgactgatc tagatggtaa gatcctagaa ggggatttaa gaccatcttc
    30121 cgacctccca actcatgtgc aattatataa ggcttggtca gaaattggta gtgtggttca
    30181 cacccattcg acagaagctg ttggttgggc tcaggcaggt cgtgatattc ctttctacgg
    30241 aacaacccat gcagattatt tctacggttc aatcccttgc gcccgtagtt tgaccaagga
    30301 cgaagtagaa gtgacctatg aaaaagatac tggcctggtt atcgtagaag agtttgaaca
    30361 tcgcggactt aacccagttg aagtaccagg aattgttgta cgcaatcacg gtccattcac
    30421 ctggggcaaa aatccagaga atgctgttta tcactctgtc gtactagagg aagtatcaaa
    30481 gatgaatcgc tttacagaac aaatcaatcc aagagttgga cctgctcccc agtacatact
    30541 agaaaaacac taccaacgta aacatggacc aaatgcttat tatggtcaaa agtaagaacg
    30601 atgaaggagg agaaaaagat aaatttagct cctcttttta catttgattt ttattgagag
    30661 taaagttgga gttgaagtaa ttttgaaaga ttttttagaa atagcgcttg atatatatgg
    30721 taaaataaaa agaattgctg tgatatcaat agatttgggg gattttttaa tatggtactg
    30781 gataaggcaa gttgtgattt gcttcaatat ttgatggatc aagaaacgtc caaaacgatt
    30841 atggcgattt cgaaagattt gaaagagtca agaaggaaaa tttattatca cattgacaaa
    30901 atcaatgctg ctctggttga cgaggcgctt cacatcatta gtattccacg aattggtatt
    30961 cacttaacgg aagagcagag agatgcttgt tgtaaactat tatcggaagt agattcgtac
    31021 gattatatca tgagtgcgca tgaacgtatg atgataatgt tactatggat aggtatttct
    31081 aaagaacgta ttacgattga aaaattgata gagttaacag aggtatctag gaatactgtt
    31141 ctcaatgatt tgaatagtat tcgttatcaa ctaactttgg aacaatatca ggtgatcttg
    31201 caagtgagca agtcacaggg ataccacctt catgcccacc ctcttaataa aattcagtat
    31261 cttcaatcgc ttctatatca tatttttatg gaagaaaatg ccacttttgt atctatttta
    31321 gaagataaga tgaaagagag gttagatgat gagtgtttgc tttctgttga aatgaaccaa
    31381 ttttttaagg aacaggttcc tttagttgaa caagatttag ggaagaaaat aaaccatcat
    31441 gaaataact
//
LOCUS       DBEJJE010000027        30307 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEJJE010000027 DBEJJE010000000
VERSION     DBEJJE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30307
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.27"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..500)
                     /locus_tag="ACL3F5_001199"
     CDS             complement(<1..500)
                     /locus_tag="ACL3F5_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0515004.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRK"
     gene            complement(537..665)
                     /locus_tag="ACL3F5_001200"
                     /pseudo
     CDS             complement(537..665)
                     /locus_tag="ACL3F5_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(727..1596)
                     /gene="rsmI"
                     /locus_tag="ACL3F5_001201"
     CDS             complement(727..1596)
                     /gene="rsmI"
                     /locus_tag="ACL3F5_001201"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0515005.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1599..1916)
                     /gene="yabA"
                     /locus_tag="ACL3F5_001202"
     CDS             complement(1599..1916)
                     /gene="yabA"
                     /locus_tag="ACL3F5_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0515006.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1956..2846)
                     /locus_tag="ACL3F5_001203"
     CDS             complement(1956..2846)
                     /locus_tag="ACL3F5_001203"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0515007.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2843..3481)
                     /gene="tmk"
                     /locus_tag="ACL3F5_001204"
     CDS             complement(2843..3481)
                     /gene="tmk"
                     /locus_tag="ACL3F5_001204"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0515008.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(3701..4498)
                     /gene="proC"
                     /locus_tag="ACL3F5_001205"
     CDS             complement(3701..4498)
                     /gene="proC"
                     /locus_tag="ACL3F5_001205"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0515009.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(4502..5764)
                     /locus_tag="ACL3F5_001206"
     CDS             complement(4502..5764)
                     /locus_tag="ACL3F5_001206"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0515010.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5774..6883)
                     /gene="proB"
                     /locus_tag="ACL3F5_001207"
     CDS             complement(5774..6883)
                     /gene="proB"
                     /locus_tag="ACL3F5_001207"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0515011.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMSGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6984..8867)
                     /gene="cbpE"
                     /locus_tag="ACL3F5_001208"
                     /gene_synonym="pce"
     CDS             complement(6984..8867)
                     /gene="cbpE"
                     /locus_tag="ACL3F5_001208"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0515012.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWIKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8870..9757)
                     /locus_tag="ACL3F5_001209"
     CDS             complement(8870..9757)
                     /locus_tag="ACL3F5_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0515013.1"
                     /translation="MEIKIETGGLRLDKALSALSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9747..10208)
                     /gene="lspA"
                     /locus_tag="ACL3F5_001210"
     CDS             complement(9747..10208)
                     /gene="lspA"
                     /locus_tag="ACL3F5_001210"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0515014.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10205..11113)
                     /locus_tag="ACL3F5_001211"
     CDS             complement(10205..11113)
                     /locus_tag="ACL3F5_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0515015.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11142..11294
                     /locus_tag="ACL3F5_001212"
     CDS             11142..11294
                     /locus_tag="ACL3F5_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0515016.1"
                     /translation="MIPYFRSFPKRKKEHPILLHYLPFSSQPYFQNQFKKISGYTPLQ
                     YRKEKR"
     gene            complement(11346..12017)
                     /locus_tag="ACL3F5_001213"
     CDS             complement(11346..12017)
                     /locus_tag="ACL3F5_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0515017.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12071..12292)
                     /locus_tag="ACL3F5_001214"
     CDS             complement(12071..12292)
                     /locus_tag="ACL3F5_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0515018.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            12565..13374
                     /locus_tag="ACL3F5_001215"
     CDS             12565..13374
                     /locus_tag="ACL3F5_001215"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0515019.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13555..14430)
                     /gene="aguB"
                     /locus_tag="ACL3F5_001216"
     CDS             complement(13555..14430)
                     /gene="aguB"
                     /locus_tag="ACL3F5_001216"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0515020.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14440..15525)
                     /gene="aguA"
                     /locus_tag="ACL3F5_001217"
     CDS             complement(14440..15525)
                     /gene="aguA"
                     /locus_tag="ACL3F5_001217"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0515021.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15522..16649)
                     /gene="nspC"
                     /locus_tag="ACL3F5_001218"
     CDS             complement(15522..16649)
                     /gene="nspC"
                     /locus_tag="ACL3F5_001218"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0515022.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16649..17908)
                     /locus_tag="ACL3F5_001219"
     CDS             complement(16649..17908)
                     /locus_tag="ACL3F5_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0515023.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17905..18765)
                     /gene="speE"
                     /locus_tag="ACL3F5_001220"
     CDS             complement(17905..18765)
                     /gene="speE"
                     /locus_tag="ACL3F5_001220"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0515024.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            19021..19625
                     /locus_tag="ACL3F5_001221"
                     /pseudo
     CDS             19021..19625
                     /locus_tag="ACL3F5_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846390.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            19605..19730
                     /locus_tag="ACL3F5_001222"
                     /pseudo
     CDS             19605..19730
                     /locus_tag="ACL3F5_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19702..21177)
                     /locus_tag="ACL3F5_001223"
     CDS             complement(19702..21177)
                     /locus_tag="ACL3F5_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0515025.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            21884..22933
                     /locus_tag="ACL3F5_001224"
                     /pseudo
     CDS             21884..22933
                     /locus_tag="ACL3F5_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            22875..23549
                     /locus_tag="ACL3F5_001225"
     CDS             22875..23549
                     /locus_tag="ACL3F5_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0515026.1"
                     /translation="MDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(23591..25579)
                     /locus_tag="ACL3F5_001226"
     CDS             complement(23591..25579)
                     /locus_tag="ACL3F5_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515027.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(25581..26339)
                     /locus_tag="ACL3F5_001227"
     CDS             complement(25581..26339)
                     /locus_tag="ACL3F5_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515028.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSATLLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQLFQEISDTLTVMASEVN"
     gene            26767..26958
                     /locus_tag="ACL3F5_001228"
     CDS             26767..26958
                     /locus_tag="ACL3F5_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515029.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(27312..27584)
                     /locus_tag="ACL3F5_001229"
     CDS             complement(27312..27584)
                     /locus_tag="ACL3F5_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0515030.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(27642..28091)
                     /locus_tag="ACL3F5_001230"
     CDS             complement(27642..28091)
                     /locus_tag="ACL3F5_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0515031.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKVYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(28078..30207)
                     /locus_tag="ACL3F5_001231"
     CDS             complement(28078..30207)
                     /locus_tag="ACL3F5_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0515032.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         8927 a         6817 c         5594 g         8969 t
ORIGIN      
        1 cattttctga ttttagttct gaaagttcca aaaggtgcaa ccgtatttac atgaataaac
       61 ttatacactt cccaagtcgc tgttttagtc gcttcatcag cccactttct catatgcggt
      121 tcaaataatt cttcctcact caacgaatca atcattgcag agatagaatt aatattttca
      181 tttaattttg ctttcaactc ttgcagagat aaatgagcgt aggtatctgt gaaccactga
      241 tataattcac caagttgatt ccatttaaat ttatccgatg gtgtttttac ttgaagcccc
      301 tttctttcat cttcttccca tttaagaacc aagttggtcc aaccaacctg ataagcaagg
      361 ttttctgctg gagttctgtc aacttcatca gctctcttat cttttaaatt ttctggaata
      421 ttatcaaatt ctaaaatata tttctcaaat gttttctcta tctcagcttt tagttcttct
      481 ttattttcgt atgttcgcaa aaaatcacct tctttctgat ttatcaatcc tttgatttaa
      541 aatgacctta tttttctatt tataccttct aagaacgcta taactgctgc tccaaccatc
      601 ggtattccgt atgggcttaa taaaaaactt aataccaaag cttctatacc aagtgataca
      661 tctttatatt atcatcacta attaagttaa acagaaacag acagaattat tacatcctgt
      721 ctccctttat tgtttttctt cccagtcgtg gtaggcagcg tagagttgac tcttattcca
      781 ctggtaaatc ttagctactt ccttaatagc ttgatttttc ttcatacctt gctggatacg
      841 agcttggatt tctaagaaca agtcttcctc gtctttttct tccacatcct gactggcacc
      901 ctcaacaatg agaagacatt cgcccttgag tggcgtttca gcaatgcttt ctaataactc
      961 agagatagta cctcgttggt attcttcata gattttggtc aattccctga ccaagacaac
     1021 ggagcggtca ccgtagactt ctaacatatt ttccaacgtg tctgctacac gatgaggtga
     1081 ttcataaaaa atctgtgttt caggataatc ttttttcaag ccaaaaaatt gcttctgctg
     1141 acctgatttt ctcggtaaaa atccgtaaaa gatatgtggc tgtggcgcta aaccactggc
     1201 aatcaaggca gaaattcctg cagaggtacc tggaacagtc acaactgcaa tttcttcctc
     1261 aatagctgcc ttaactaaat catgaccagg gtctgaaatg ctaggcaaac cggcatcaga
     1321 gacctgagca atactttgcc ctgctttcaa gaaaccaatc aaatcaggaa ttttttcctt
     1381 ggcattgtgc tcatgaaaac tgatctgctt ggtggaaatg tcaaaatgct tgagcaaaag
     1441 ccctgtattg cgcgtatcct cagcagcaat ccagtccact tctttcaagg tctggatagc
     1501 acgaaaagtc atatcatcta gattgccaat cggcgttgcc actagataca gcttgccata
     1561 gggagattgc cccttaaaac ttttttgaat ttgcatgcct actccctgta taacaactca
     1621 tcacagaaca tacattcttc gtcctgctct cgacgttgtc cataaaaatc attacatacg
     1681 tgaaatccat cacggtaaat acgacggaca ctttcgcgaa catgcttggc cttgacggga
     1741 gcgtctgctt ccacctcacc caagcgttct cgcaacttac tattttccaa gcgaagagct
     1801 gtattttctt ctaccaagct cttgagattt ttcttgatgg cttccacatc ggctaaagtt
     1861 accaataatt gttgggaaaa atcatccagc gcgtcaaata attctttttt gtccataaaa
     1921 cagccctttc ctttctttat cattcatttt tgagtttata tttctttcaa gaccagatat
     1981 tccatggcat tttgaaagct gacattagct tgccacattt ttctagcttc tagtaaatct
     2041 tgtagaatca ctcttactct tacctgcaag aggtcctgcc cacagagaac ttcaagaatc
     2101 cgtaaaacct gatcctgttt ttccttatca tctgccaagt tggctaattt ggcaacctgt
     2161 agataacttt cttttttctt agctactaac caagtcagca ggcgttcact ttcatcgacc
     2221 aaggtccaaa aacttgcctg attagccaac ttttctgctt cagctcgcga ttgactaaac
     2281 ttagctaaaa gagtcgcttt tttcttaaca agtcccattt gttctaagag taagataagt
     2341 ttttcttctt gctttttaaa gtggaagatc tgagtccgac ttcggattgt cggtaacatc
     2401 ttttcctcat cgctagtcaa gaagaaaata taaacttcac tctggggttc ttcgatgacc
     2461 ttgagcagag aattggctgc gttgggatgc attttatccg cttgctcgat gataaagacc
     2521 tgttgctggc tttcaatccc tgcttgagaa aactgtccca ccaattcccg aatgcgttct
     2581 gtcttgatga cctgattgac tggcttaatc aaggtgacat ctggaaactc ttcctgttca
     2641 atcagcttgc aacttcggca tttctcacat ggtaagacgc caactttatc cgtacaaaag
     2701 aggctcttag ctaaaaattg cgccatttcc aagcttccaa agaaacctga aaagagatag
     2761 gcgtgattga gctggtcttg ttctaagata cggacaaaac ggtcaaactg agctggttgc
     2821 caagccttta gttgatcttg tttcatttgg ccaagcccat tccgtcaaac aagacagcct
     2881 tggtagtttc cacaacttgc tccaaaggga gactagcatc aatcttgaca atgcgatttc
     2941 cttctttttc caggagagaa aggtagcctt gacgaacttt tttatgcaag tccaaccctt
     3001 ccaaatccaa acgattaacc tcgcggtcac tattagcagc aatacgagcc agcccttctt
     3061 ccacctcgat gtcaaaatag agtgtcaaat cgggtttgag gccatctgtc gcaaactgat
     3121 tgagccagtc aatggcttca atatctaagc cacgaccaaa tccctgatag gcaacagaac
     3181 tatcgataaa acgatccatg atgaccaact tgccagcttc aagggctgga agaacttttt
     3241 ccaccaaatg ctgtctgcga ctggcaatat agagaagtag ctctgtttta gcatccatct
     3301 gagtatgact tggatccaaa atcacttccc gaatcttctc cccaatcaag actccgccag
     3361 gttcacgggt cgtcagcacc tttactcctt tttcctctaa aattggtagc agagcctcta
     3421 aaacactggt cttgcctgct ccctctggtc cctcaagaga gactaaaaat ccttttgaca
     3481 tgtctaactc atttcttttt tactacttct attctatcaa aaaaataggg gtttgtgaca
     3541 atctttttgt cttctcattt catactcaat gaaaatcaaa gagcaaacta ggaagctagc
     3601 cgcaggctgt acttgagtac ggcaaggtga agctgacgca gtttgaattt gattttcgaa
     3661 gagtatcaac caccataaaa gaggcagata aaactacctc ttatttacct agttcttgtg
     3721 ttcgtttata ggcttgatga actgcctcca tgactatgcc tcgaaaagca tgcgcttcta
     3781 agcttgctac gccagcaata gtcgaaccgc ctggactaca aacttgatct ttcaaaactc
     3841 caggatgttg ctggctttct aggaccaatt gcccagctcc taccacagtt tgggctgcca
     3901 ttttcaaggc tgtttctcgt ggtaatcccg tctgaacacc tgcatctgcc aaggcctcaa
     3961 taaagagata gacaaaggct ggtccacagc ctgcaagacc tgtcgctgca ttgatcaagc
     4021 tttctcctaa ttcaaccaag agaccagcct tggataaaag ctgacaaaag agctcactgt
     4081 cctcagccct gcaattagga gacaaggcat aactaatcac tccttgcccg atagaagcag
     4141 gggtattagg catcatacga ataattcggt gttgacttgg gataagactt gctagttttt
     4201 ctaaggtcaa tccagctgcc atcgaaatca aaagaagact ttctcttttt tcaaggatgg
     4261 tctggtattg agaaagcagt tcagaaaact gagcaggctt aactcctaga aaaatcacat
     4321 ctgcttctgc aaacatttct tcattgctgg aagcctgacc accaaagtct gcaatgaaag
     4381 catctacctt agcttgacta cgattggcaa ggagaatctc atctgacgtc ctagtctgca
     4441 agacagattt tgccaagcta gcacccatat tccccaaacc gataaatcca atcttcatct
     4501 cttactccct tatctgccca tcaccagcaa ccacatactt gtagctggtc aactctttca
     4561 agcccattgg accacgcgcg tgcaatttct gagtagaaat ccccatttca caaccaagac
     4621 caaattgtcc tccatctgtg aaacgagttg aggcattaac atacaccgct gcagagtcca
     4681 cttgatctgt aaagtatgct gcagcttcag cattttccgt cacaatagca tccgaatgat
     4741 gggtgctgtg ggattcaatg tgcgcaaccg cttcttctaa actgctcaca accttaacag
     4801 caaggacata gtctaaaaac tcggtgtcaa agtcttgggt ctcagctgct tgacctgaaa
     4861 caaactggct tgctttgcta tccaagcgga attgaattgg ttccagtcca gcttccttac
     4921 gctctgcaac cagcatttga tccaagcgag gaaggatgct tgctgccttg ttttcatgaa
     4981 ccagcagaac ctccatggca ttacaaacag aaggacgact ggttttagca ttgttgatga
     5041 tagacagcgc cttgtcttcg tctgcatcct tatccacata gacatggaca atcccagtcc
     5101 ctgtctcgat aacaggtaca atcgcattct caaccactgc attgatcaag ccagctcctc
     5161 cacgaggaat gagaaggtct agatagccct tggccttcat catagcataa ctactttcac
     5221 ggctagtatc ctccaccagt tgaatcacat ttggatgaat agtagtcgtc tccaagccct
     5281 tcttcaaggc tgtgacaatg gcatgggttg tttgataggc atccttacca ctacgaagaa
     5341 caaccgcatt tccactctta agagtcaaag cagccgcatc agacgtcaca tttggacggc
     5401 tttcatagat aataccgatg acacccatag ctacacgttt ttttgtgata accaaaccat
     5461 tttcaagctg acttgtttct aaaacttcac cgattggatc tggtaaggca accacttcac
     5521 gaattcctct tgccatcgct tctatacgat ctgcatccaa ataaagacga tccaacatca
     5581 catctgagat tttcccctta gccgctgcca tatcgagggc attagccgct aaaatttcct
     5641 cagtagcagc cactaagtga tcagccatgg ctagcaaggc ttggtttttc acttcttcac
     5701 tagctgtgtt aatcgatttt ttaacagcct gtacctgttc aaattgttct tgtctactca
     5761 ccatagttta cctctaaaat tctgtaaaaa gtagttggat ttcaggagta atggaaatcc
     5821 agtcgtcacg gtaaatcaag acacccttgg ctttttgaga acgcaacata tcctccaaag
     5881 cagatgctcc aaattgcacg cgtccttttc caagtgattt tccactttcc ttgtcaaata
     5941 ctgtcacgat atcaccgtaa gaaaaggctc cttctgcttc aacgatacca gataagagaa
     6001 gactctttcc atgttgagag agagcttccg cagccccttt atcaacccaa atagaacctt
     6061 gactctgagc atagaaggca agccattgtt tctgggtacg aagccccttc tcttgagcaa
     6121 caaagtaaga accatcctcg gtctcctctg ccgcctcaat catggaatct gatttcaagg
     6181 atgagcagat ataaacagga actcctgatt ccgtcgcgat agttgcagcc ttgattttgg
     6241 ttaacatacc cccagttccg tttgacgaac cagctccacc agacatatca ataatctcac
     6301 gattgatggt ctcgattctc tccaagcgtt tggctcttgg atctgaatta ggatttccag
     6361 tatagagacc gtccacatct gtcaagaaaa ctaaaaggtc tgcttggacc atcgccgcta
     6421 cttgagcact tagagtgtca ttgtccccaa ccttgagctc atcaataacg acactatcat
     6481 tctcattgat gataggaatt gccccacggt tgagcaaaac cgacaaagcc tgatgggcat
     6541 ttttataacg acgcttatcc acaaagtcat cttgggtcag caagatttgt gcagaaacga
     6601 tttgacgcaa gagaagattg gttgtatatt cttccaacaa aagcccctgc cctaccgctg
     6661 ctgaagcctg tttatcagca attttagtcg gacgcttttt aaatcctaag gctccaaaac
     6721 cagccgcaat ggcacctgaa gacaccaaaa tcaactcatg accagcctcg tgcagcatag
     6781 ccaactgctg ggtaatatcc tttaccttac tacgtgataa acttccatcc tcatttgtca
     6841 gagaagaagt acccacctta aagacaatcc gtttgtattt catagtctca ctccgattat
     6901 tcatatttat ccattataac atgaataaca gaaaatagaa aagagttgat aggaaaaaga
     6961 aggccctaaa accttctttt ctactactgt tctgattccg atttgtttac actcgtttca
     7021 gagctttgtg aagttgagga tgtcaaatct tgactagttg aagaatttgt aacactttca
     7081 tgttgactcg tttctttatt ttcaagatcc tttttcacta cttctttgga ttcttttatt
     7141 tctgaatgac ttgtagtttt aattgtagca gatttctcga tcggaacatc cactaaccag
     7201 gcaccacttg aatccacagt atagccttct ggtgtcttac cattcacaag taattgacca
     7261 ttttctttca agaagtacca tttatccttg tctttaatcc aacctatagc tcgtgaacca
     7321 tctgtcttgt agaaatacca atcatttgcc tttttaagcc agccttgctt catagctcct
     7381 gattcttcta gatagtaatg atgtccagca acttctatct cacctgtctt catgatacca
     7441 gtagaatcca tatagtacca ggcttcttta tcttttaccc agcccgtttt catttcccct
     7501 gatggagcaa agtaatacca ttgcccctta tattgaagcc aacctgtctt catagagcca
     7561 tcaacatcca aataatacca ctgctcttta tcttgaatcc aaccaatttc catctggttt
     7621 tctttgttaa aataatacca gattccagcg attttcttcc aatttttagc agcaacacca
     7681 gagtctgtca aatagaacca acgattgttc cattttttcc attgattctg taataagata
     7741 cccgtttggt taaagtaata ccattcaccc ttaatttcat tccaaccgac agcatattct
     7801 cctgtagaat caggcgcttg ataccaccag tttccatatg aactcttatg ccaaccagct
     7861 tgaaaacttg gaatcggctt gtaggaagtt gaaatgttta ctaaaccgtc ttgtcgaata
     7921 tcaaaaactg tcgcatcata gtctttgctg gctgcgttga ttctctcaat tcctcgttct
     7981 ttgatccaat taacatactc actatcaaca ccatttttcc aaggtagact atccgaagtt
     8041 tgaacaatca aactcggact caaattttta atgaaatcct tggtatttga tttgttggta
     8101 tcatggtgat gattaaactt catcaaatca acttttccaa tgagaggacc atacttgtct
     8161 tctgctccat gaacattatc taagtcgccc ccaaggtaaa ttttcttgcc attgactttt
     8221 accacactaa tcaaggaatt ggaattatca tcccaaattt tctttaattc acccgatgaa
     8281 tcggtttcat tttcatagtt atagagctca atatccatgt ccccaaactg aaaatgagca
     8341 tccccttgtg tgatattttg aataactgaa acaccttttt ctgaagcagt ctgtaaaacc
     8401 ttatcataac cgtacagatt atcccataga cgttcagaat tagtaatacg attatcacta
     8461 tattttttaa gatagactcg gtcaactgga taggtagaca gtaattcatc aacatttcca
     8521 atatgatcac tgtgggtatg ggtcaccaaa ataaaatcaa gtttttggac acccaattcc
     8581 ttcaaacgac gaaagacacg gtctgttaga acatgcttat aagacgtttc aattccttct
     8641 ctccatggat agcgagaatc acttccatct gggaaatcat aatcttctcc tgtatccacc
     8701 atggcaaaat gtccattgct ttcaagaata atcgcatcac tgccaccttc ttgaacattg
     8761 ataaagtgga ttttatttcc tgaactttct tgagcctgaa cattcccata ccatgacaaa
     8821 cctaaaaaag cgcctacaag tgctaaacta gttaatttct ttttcattct tactttctca
     8881 atctctccaa ggtttcctta aaaatctctg ggatatctgc tttaaattcc aaggtcttac
     8941 ctgttctcgg atgagtaaaa cctaaagtct tggcatgaag aaattgtcca tgtcctttca
     9001 aagtcttgcg aggaccatag acctcatcac cagcgactga atggccgata taagccatgt
     9061 ggacacggat ttgatgagtg cgccctgtct ccagttgcaa ctctactaag ctataatcgc
     9121 caaagcgttc caagacgtga aaacgcgtca ctgcaggctt ccctttagca gttacagcct
     9181 gtttcttacg gtctttttca ctccggccaa tcggcgcttc aattacacca cgatcattag
     9241 gcagatttcc atgaacaatc gcccaatatt tgcggagaga ctttttatcc ttgagttctt
     9301 gggcaagtgc tagatgcgca tcatcgtttt tagcaatcat gagaagacct gacgtatcct
     9361 tatcaatacg gtgaacaatc cctggacgca gaaccccatt gatacccgac aagtccttaa
     9421 tatgatacat gagggcattt actagggttc cactggtatg accagcactc gggtgcacaa
     9481 ccattccctg aggtttgtta acgacagcca catcctcatc ttggtagact atttctagcg
     9541 gaagatcctc agccacatac tctaatacct ctggttctgg cacatggtaa gtgacgacat
     9601 caccctcttg gactgtgtat ttagctttct tgacttgacc attgaccaag acctggcctg
     9661 atttaatttg ttcattcgcg agactacgtg ataattctga caaagctgac aaagccttat
     9721 ccaaacgcag accaccagtt tcaattttaa tttccattta tttcctcttt tagcattgca
     9781 atcaataaaa taatcactcc aaccgtcaga tagctatctg ccacattgaa aattgcaaag
     9841 ttgataaagt caaggtggaa catatccaca acaaagccct gactgaccct gtcaataaag
     9901 tttccaagac cacccgcgat tattagagtc aaacccaaga ccatccagaa tgagtcctcc
     9961 atgtgtttat gtaaatacca aatggcacct atcacgacaa ccagagtaat gacagcgaat
    10021 aacagctgct gatcttgtaa gatagaaaag gctgcacctc gattttgcag gtaggtcaag
    10081 ctaacgaaat tgggaatcca ggagcgcact tcacccagtg gaatctgctg gacgatatag
    10141 gatttgacca actgatccag cccaattaaa agcagtacaa tgactgccac tattgctctt
    10201 tttttcatga tttcctcttt tgatcaaaat attcttgcat gacttctacg aagagagtcc
    10261 cagcttgact aagctccact tcttcacgtt taacatagac catgcggtta tctaggttat
    10321 ccttgagacg aataactgta ataccattaa cactgtcact atctaaaaat ccagaacctg
    10381 tcgcataggc gtccgtccgc tccaaaatac cattcaaggt ggcacggtct gtcacattaa
    10441 acatctgtga gctagcgctg gtatcgacaa agttctctga ataataaagg tactcgtctt
    10501 tctcttgagt gaaacgaacc gttggtaaat ccgctaaatc ctccatgact aattcctctt
    10561 tctgggctaa aggatgaccc tcacggagat aaatatgggt atggaaagga atcaattcga
    10621 tgacctccag acctaatttt tcaacccgtt gcataatccc ctttttattt tgattgttga
    10681 ggtagataat cccaatctca ctatgccctt gcgccacttc atctaatatt tgaacagtag
    10741 ttgattcaaa aatacggaag ttcttatagt caggatagcg ctctgaaaag gccgtaatag
    10801 ttggtggcaa gaagtcatag tgctggctag caacagaaaa ttcatctttt tcttcttcag
    10861 gattggcata ctgattttga aaaatatcaa atcctttaac caattcttgc gatttttcat
    10921 agaattccat cccacgacgg gtcaagaaag tccctgagct ggtccgacgg aaaatcttaa
    10981 aacccaactc tttttccaaa tcacgaacag aaatagacag actcggctga ctaacataca
    11041 tcttttcagc agcttcacgg aaagtaccac tattggcaat ggccacaaca tagcgtaatt
    11101 gttgaatgtt catcttctac ccctaacttc tttatctttt cattatacca tattttagaa
    11161 gttttccaaa aaggaaaaaa gaacatccta ttcttcttca ctatctgcct ttctcaagcc
    11221 aaccttattt tcaaaatcaa ttcaaaaaaa taagtggcta cacaccactt cagtatcgga
    11281 aagaaaaacg ttgactattt gtgaaaaaag aaaatgctgg aaagttccga cattatttta
    11341 gtaagctaac ttcctgaaaa taggagcaac cacacgtccc agaaggcagt gatattaatg
    11401 agaatatgaa ctagtattgg atagtagaga tttttagtca tgcgatacaa tagagctaaa
    11461 ataagacctc cactagcata aatgaaaaaa gcaagaggag ttaaagcaaa attgatatga
    11521 atataaccga aaataatagc agaaagcaaa acatctccgt accaaggtga gtttttgaaa
    11581 aaggttgtca taagcacacc tcgataaatc aattcctcag caataggggc gatgaagcaa
    11641 acgatgagca agaaataagg gaactcctgt ctccccatca tttctaccgt ttcattcaaa
    11701 gaaatttgat ttgaaggcgg ggatatgaaa tacgaaaaga ggaagtcaga catatatgaa
    11761 atgatgtagc ccagtaaaag gtagatgaag tacctcagct gccacttgaa atgaaaaatt
    11821 ttctttcctg caaaaaccag tagatagatg accgctaaga aaagaactcc gctctccatc
    11881 aaaagcagaa tctgaaaaaa ttcacgactt gctggtagat agggctttgc gaggtgattg
    11941 aaaactctcc aaaaccaagt tgatttgtaa aaaattaagg acaatgctag taaaatttga
    12001 atagcccgtt ttttcatatt aaatcctctg ttttctcccc ttgtttcttc atattcctaa
    12061 taaattttac ttaaaatctc gcagcacttc ctttgcaaag atgattacct cctccaatat
    12121 atcctaaatc atcggttcct ctgggacaaa atccatgaac cggcatagtt aatactggtt
    12181 ccatttgcca aggataataa ccattaggtt ctttaccata gggatctgct ccaccttgta
    12241 tcagctctaa ttcttcattt gttagattta tattttttgt cattaaaatc atgatatatt
    12301 tcctccgtta ttgtttagat tagttgagta atctgctact catacctact tacaaaaaaa
    12361 actattatat taagttggtt ttttaatttg tctagttgca acattgacaa acatagtata
    12421 gcatatcttt gccaaatctc ctcttcaaat catgaattgt catcaaaaca tcttaaacta
    12481 taaaatcaat tagtctcaag ctttctatca atttcttctc caaaatatgc tataataata
    12541 gcaaaagata aagaaggaag acctatgatt aaactactag ccttggatat ggatggaacc
    12601 ctcctcaatg aagccaagga aatcccacag gctcacatcg ctgctattca ccaagccatt
    12661 gaaaaaggtg tcaaactggt cctctgtacg ggtcgccccc ttttcggtgt cctcccctac
    12721 tacaaaaaac tgggactcga cctccagaac gaatatgtga ttgttaacaa cggttgttca
    12781 actcaccaga ctagcgactg gggcttggtt gactggcaag aactgagtcc agctgacatc
    12841 gaatacctct atgaccttgc tgaaaagagt gatgttcagt tgacactttt tgacgagtca
    12901 cattattttg ttctcggtgg caagcccaat caagttattg aaaatgatgc taaactagta
    12961 ttttcagacc tgactgaaat ttctcttgaa gaagcgacta gtggaaagtt ccggatgttc
    13021 caaggtatgt ttttaggaac aaaagaacaa acagacgatt ttgagcagcg ttttgctgaa
    13081 gagctttgcc aacgattcag tggagttcgt tcgcagcctg tcatttatga agcaatgcca
    13141 cttggaacga caaaggctac tgctctttca cgacttgctg agattttgaa gattgattcc
    13201 tcagagatta tggccatggg cgatgctaat aacgatatcg aaatgctcca gtttgcaggg
    13261 cttgggattg caatgggaaa tgccagcgat tatgtcaaat ctcttgcgga tgccgttacc
    13321 tcaagcaacg aagaagacgg cgttgcgcgt gctattgaga aatatattct ataaaaaaag
    13381 aaaagcaaat agacagaagt tactgctatt tgcttttttg ctaatattta aaatacggac
    13441 taatcaatag acaagaatag cgaatcataa aaatcgattt actagatgcc atagtatctt
    13501 atagttgcta ataagaagtt agtctagcag aatgaatctc tcatttctcc cacactaatc
    13561 tgtaatttgt ctatacattt ctggtcttct atctcgaaac aagccccagt ttagacgttc
    13621 acttgctccc ttgtctaggt cataagtagc taacagaaca gcttcttctt gtctttcagc
    13681 tcgttctaga atagctcctg tttcatccgt cataaaggag gaaccgtaga agtcaagact
    13741 ggaactctgt ccgccatttt cctcactagg agtaacctcc tctaaaccat aacgattggc
    13801 tgcgatgact ggaacaatat tcgctgctgc gtgcccttgc atagtacgtt gccagtgacc
    13861 acaactatct gtatccaaaa ttggctctga accgatagct gtaggataaa agagcaattc
    13921 agcaccattc aatgcaagac agcgggctgt ttcagggaac cattgatccc aacagatacc
    13981 gataccaatc ttagcatagc gagtattcca gaccttgaaa ccagtgttac caggcgtgaa
    14041 atagaatttt tcttgataat aatggtcatc tggtatatgg gtctttcgat aaacgcccag
    14101 cacttcccca tctgcatcaa tgacggcaat agagttatac aagacattac catctttttc
    14161 atagaaactg attggtaaaa caacttgtag ttccttagca atcaccttaa aatgctgaat
    14221 ggcagtattt tccgctacag attgggcata ctggtagtag tcatactgac gttcctgaca
    14281 gaaataggga tgttcaaaca actcgggcaa gagaataatt tgggctcctt gctcagcagc
    14341 ctgacgtact aaacgctctg cggtttggat atttgttgcc acatccttag cgcattgcat
    14401 ctgaatggtt gcaactctta catttctcat ctttttctcc tattctggaa tttgttgggt
    14461 gatacagtgg atattgccac cacctaagag aatatctctg gctggtattc cgacaacttt
    14521 acggtctggg aaacacttgc tgaggatatc taaggccact tggtcgttta catcctcaaa
    14581 ctgtggaacc aagacagcct tgttggcgat ataaaagttt acgtaggaag ctgctagtcg
    14641 ttcacctgcg tatcgctctt cttctccttc ttcatagatg tagcctggca aatcttcttc
    14701 tgtcacaact tgtcgaactg cagggatagg caatttatga atggtgaagt gacaaccttt
    14761 tgcatctgtt tcctgttcta agagttcgag atctgctttt gacatggcat actggggatc
    14821 attttcgtca tctgtccaag ccaaaacaac ctcagcagga ccaacaaagg cagcaacatt
    14881 atcgacgtgt tcattggttt catcctgata aataccataa ggaagccaaa taactttttc
    14941 agcaccaaga ctttctaata atgtgttttc aatctcctct ttagtcaagt taggattgcg
    15001 accaggacta agcaagcaac tttcagttac gagaatagtt ccttgaccat cgctatggat
    15061 tgcacctcct tccagtacaa aaggtttagc atcatagaca ggcctttcca aggcctcagc
    15121 aaaacgactg gctacttggt catcctcttc ataatcttga taaagaccat cataggtgcc
    15181 tccccaagca ttgaaggccc aatccacggc taatttctta cctttatcat tgacgagaat
    15241 ggttgggcca gtatcacgcg cccaggcatc attggtggga atgtctaaat aaacaacctt
    15301 gtccccaaga taggattggg cttcagatag ataggcctgc tccaccaaaa gatagactct
    15361 ttccccttct gctatagtct cgatgatctg agtaaatgct cttttagcat cctttccttg
    15421 aaaaggccat gatcctggtc gagtcggcca tatcatgagg gtaccatgat ggggttcgta
    15481 ctctgctggc atgtgatagc ctaatttttt tggactgtcc atcatgataa tctcccttta
    15541 aagtcttgat agccaaaagc tttgagtaag ctacagtctc cctgttcgtc catgagatag
    15601 agacttggca atccaatacc attaaaggta ttatttttga caaaagaata aatggccatg
    15661 tcttgaaaat aaagtctgtc tccgatttgg actggatttt caaaactata atcaccaatc
    15721 acatcgcccg tcagacaggt attagaagaa agtctgtagg tatgggcttt ttcctgtgcc
    15781 tcaaagccat ttctcaaagg tggacgatag ggcatctcaa gtacatcagg catatggcag
    15841 gtcgcagagg cgtctaaaac caagatttcc ataccgtttt ctacaatatc taatacctca
    15901 gttgctaaat aacccgcatt aagcgcaatg gcttcaccag gctcgatata gatttcaaga
    15961 ttgtaagttt ttcggatacg cttgatttct gaaatcagca aatccacatc gtaaccttct
    16021 cttgtaatat gatgaccacc acccatattg agccatttta cctcatgtaa gtagggacca
    16081 aactgttctt ctactgcttt caaagttgtt tgtaaatcat ctgctccctg ctcgcaaagg
    16141 gtatgaaaat gaagtccgtc aaccaaatct agcaaatcac tcggaatctt gtctatagta
    16201 actccaaagc gagaacctgg tgcacaaggg tcatagagcg cgtgatctcc ttgagttgaa
    16261 cactgagggt tgaggcgcaa accaacactg acaccagcct ctcgacaacg agccccatgc
    16321 ttacgcaact gtctctctga gttaaagacg atatggtctg ttatcccaag caattcctcc
    16381 aagtctgcat ccttgaaagc aggcgcaaat acatggactt caccaggaaa ttcttccctt
    16441 gccaatttgg cctcatagag tccactagct gtcgtacctg atagatactg gctaatcaag
    16501 ggataagttt tgtagaggga atatgccttc tgggcaagca agaccttgca accgacctct
    16561 tcttgtacat attgtagaat gcggcaatta gcttctaact tggccaagtc aataacatag
    16621 gctggtgttg gtacttgttc taacttcatt agtccaccat ttgtggattt tcaaccacaa
    16681 cccatggcaa accatactca ttcaaagctt ccatgaatgg atctggatct aactcctcaa
    16741 ggttatacac tccagcttgt ttccaagttc cgttcatgac taattttgtc ccaatcatgg
    16801 ctggaacgcc tgtcgtgtat gaaattgctt gtgacccgac ttctgcatag cactcttgat
    16861 ggtcgcaaac attgtagatg tagatagtct tttcaacgcc atctttgaca cctgtaaaga
    16921 tacatccaat attggtttta cctacagtac gtgggccaag gctagcagga tctggaagca
    16981 aggctttcaa aaattgaatt ggaacaattt cttggccgtt aaagttaatg gtatccgtac
    17041 gaaggagtcc aacattttca agacatttca tgtgcgtcaa gtaagattga ccaaaagtca
    17101 taaagaaacg aatgcgtttg acacctggaa tgttcttggc caatgattcg atttcttcat
    17161 ggtgaaggag atacatatct ttttgtccaa cttgagggaa atcatactca cgcttgatag
    17221 acatagcttc gacttcgacc catttcccat cttcccagta agaacctggc gcagaaacct
    17281 cacggagatt aatttctgga ttaaagttgg ttgcaaatgg ataaccgtgg tcaccgccat
    17341 tacagtctaa aatgtcgata taatggattt catcaaaata gtgtttgagg gcataagctg
    17401 aaaagacact agttacacct gggtcaaagc cagaaccaag aagagcagtc aagcctgctt
    17461 ctttgaattt ctcttgataa gcccactgcc atgagtagtc aaagtaggct gtaaaaccaa
    17521 gttccttaca acgtttttcg tagatagcac gccactcagg gtcttctgtg tcttctgctt
    17581 cgtagttggc tgtatcgata tagtgaacac ctgttgccaa acaagcatcc ataatggtta
    17641 aatcttgata aggcagagct acattcaaaa cagcttctgg tttgtagctt tcaatcaggg
    17701 caatcacttc ttcaaccttg tcagcatcaa gtgctgcagt ttcaatttta gtacttgttt
    17761 tgccttctag cttcgctttc aagtcatcgc attttgactt ggtacggcta gcaatcataa
    17821 tctctgtaaa tgtttcgcta tcttgacaaa tctttgaaat agcaacttgg gcaacgcccc
    17881 cacaaccaat aactagtaaa cgactcattt ttttccttcc tcttcttcta aaatgtcctc
    17941 aacatacttg ggcaacataa aggatcccac gtgtaagttt gcagtgtagt attctgtgaa
    18001 aagctggcgt tttttccaac cttccttgtc aaaatctttg acagggtggt attttttcga
    18061 tgcaaatcca aacaaccaat agccagctgg gctagttgga atatgggcct gataaacccg
    18121 actgattgga aaggattgat tgaccttgcg gtgcatgctt cggcaggccg actcatcctc
    18181 gtcaaagaag ggactcccat gctggtaaat catgatgccg tcttccttca gagctcgata
    18241 actattgccg tagaattcct tggtaaagag tccttccgta tggccaaatg gatctgtcgc
    18301 atcgttgatg ataatatcgt aatcatcttc gcagtttcgc aaaaagcgta gcccattttg
    18361 gtagtaaatg gtaacacgag gatcatctag ccctgcagca aagtctggga aatactcacg
    18421 acagacctcg accaacatct catccggttc cacgatatcg atttgttcca gttcaggata
    18481 gagtgttaat acttgggcaa caccgccgtc accaccccca ataaccaata ctttctttgg
    18541 atttgggtgg acagccatgg gaacgtgaac ggtcatttca ttgtagacga aatcatccgc
    18601 atctgagaac aagacatggc catttaaaat cagtattttc ccaaaagctg gcgtatccaa
    18661 gacttcgata tcctgccatt cactttttcc agcgtaaagt tgcttggctg ttctcagaga
    18721 caatttgaca tctggagtat gaacttcaga aaaccataaa tccatctatt tctccttata
    18781 ttatatttag cgcagttagc tactgccaaa gcccaagtga tatacttgga ataagccact
    18841 gtggattagt ttattccctc caatcgcttg acgatttccg aaaggctcta accacagttt
    18901 tttgtttcaa ttggtaatga gtttgataac gcatagacgt tttatctcgt ctaaggtaac
    18961 aaggcaaaaa attcgtggat aaccaagtag acttgaaata ctacatctgg aggtactccc
    19021 atgctttatg tgggcattga tgtcgctaaa aataaacacg atgttacagc cttgaatgtt
    19081 ccaggaaaaa ctgttcttaa accactcact ttttcaaata ataaagctgg ttttgaactc
    19141 ttagatctgt ctcttcgaca actcaaccaa gactgtctca tcgctcttga aaataccgga
    19201 cattatgcct ttaatctact gaacttcctg catgaacaag gatataaagt ttacacctgc
    19261 aatcctttgc tcatcaagga atttgccaaa tcattatcac ttcgcaagac taaaacggat
    19321 aagaaagacg ctcatggcat cgctcttaaa cttctttctg accccaatcg tgaacaattt
    19381 caacacgata atcggcaagt agaactaaaa atactggcta gacatattca tcgtctcaag
    19441 aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc tttcctgagt
    19501 tggataaaat cgttggaaag cattcagaat atacctacca actcttgaca cgctacccta
    19561 atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag cgattgaccg
    19621 cttctaattc aagggctttt tgccgtgctc taaaatcatc gccaaatcat caaattgaaa
    19681 taagaaatag tttagataaa actattgact tttcttatag tttgtctttc tcttaataac
    19741 gttgatatga ttgacctctg gatcttccgt cccttggagg gagcaaccac gttccttggc
    19801 gaattggata tagtctacaa tttctcgtgt aatgcgttca ccaggagcca agataggaat
    19861 ccctggagga tagcacatga caaattctcc acagacctgt ccaacagact catctaaggt
    19921 caaacttttt ctctctgaat agaaggcttc ttgtggagac agcaccaact cgggctgaat
    19981 atattctcca gctattaagt ccttcccatc tcgtgaatag agtctcttaa tatcagccag
    20041 agcaccaacc aagcgctcga tgtcttggat gcggtcgccg atggaaatat aggccaagat
    20101 attgccgata tcaccaaact cgatctgaat gtcgtattcg tctcgcaaga ggtcataaac
    20161 ctcgatacct gttaagccta ttccctgagt gtaaactgac aacttggtta catcaaaatc
    20221 acagaccgac acaccatcta ttaactcttt tgagtaagca tagtaaccgc caatggcatt
    20281 gatttcatga cgagcgtact cggatagctc aatgacttcc tcaaacgact ctttaccacg
    20341 aagggccaag ttgcgacgtg aaatatccaa actagccatc aataagtaag aggcagatgt
    20401 agactgggtc aggtttataa tctgacgaac gtattcggga ttcatctgct ccccgattaa
    20461 aagaagcgaa ctttgtgtca aactcccacc agacttatgc atggaaactg ctgccatatc
    20521 agctcctgca tccatagcag aaattggaag tttaccagtg aaatgcaaat gcgctccatg
    20581 ggcttcatct actaaaacca tcatgccagc ttcatgagcc atttctgtca acccctttag
    20641 gtctgaacag ataccgtagt aagtaggatt gttgattagg atagccttag catctggatg
    20701 gtcctttatg gcctgtgcta ctcggtcatt ttcaagacct aaagcgatac caatcttagg
    20761 atctacactc atctcgatat agatgggaat ggcaccacat agaaccaacg cattgatagc
    20821 agatttatgg acatttcgtg gcagaataat cttatctcct gccttgcagg ttgccagaat
    20881 catagtctgc accgatgaag ttgttccacc aatcattaga aaggcatggc tagctccaaa
    20941 agcatctgca gccagctcct ctgcatcacg aataatcgaa ataggatggc ctaaattatc
    21001 caagggtttc atcgaattga catcaatgcc tacacatttt tctcctaaga gttcgacaag
    21061 ttctggattt ccccgtccac gcttgtgacc tggaacatca aagggaacaa tccttttctt
    21121 gcgtaacttc accaaggcct cataaattgg ggcttggttt tgatctaact ctttcaaaac
    21181 atactccttt caatattttt aggaccttat gaaaactaag gaactaaagg ttgactcatg
    21241 aaaaaagagc aggttttcac ctgctctgca atcttctgac gtgtttattt tggtttctgt
    21301 tgagtatgtc tgttcccgat gtttcctaac tctctagtag caaatattac gtactttatt
    21361 gatcgtttca caagatgacg tgtgctttca ccacactaaa aatttatgaa ttaggacaag
    21421 tgtcctaaca tcaacttata aaagtaggct tttaacccta tcaataatgt ggcttttcaa
    21481 ccacgcttcg gcattcaacc ctgcctgtcc gtaggcattt tttactcggg tttatatttg
    21541 ctagaaaaca tcatctcatt ttctaagctt tattactata tcatgttttt aagaacttgt
    21601 aaagtatttt ttgataaaaa acaaaaatat aatagattga aactagaata gtacacttct
    21661 gcttctaaaa cattattaga aatagatttt actgtcctga tcgatttgtt ctgttcttgt
    21721 ttcattttac tatatgttcg taaatgaaag ttctataatg aagttagcca cccagccctc
    21781 ctaaaaatta gatggttcaa ctagctgata gctcttgtag gcataagaaa acacctctgt
    21841 gttatacttg ttgttcaacc acaaacacaa gaaaggcaca gagatgcaag acaattatac
    21901 tacaaaagcc aaacatttga caatcgatag ccgtcgctta atcgaaagat ggaaaaaaga
    21961 agggaaatca aatagagaaa ttgcctctct gcttggaaaa gttcctcaaa ctatccacac
    22021 tgaaatcaag cgtgggacag tccgacaatg tcttggaaaa gggcgcttca aagaggttta
    22081 ttctgccgac tatgctcaac agtcttatga aaacaatcgc aagcgctcgg tcaagaaatc
    22141 aagcttgaca aaggaactaa aggaaaagat tctccactat cataaccaaa aatttttgcc
    22201 tgaaatgatg gttatggcta aaggggttaa cgtgggaatt tcaaccattt actattggat
    22261 tcatcatgga aaattggggt aaagcaagca ggatctgctt taccctagaa aaggaaaagc
    22321 gcttaagaaa caggccagca ccaactttaa acctgctggt caatccatcg aacagcggcc
    22381 tgaagctatc aattttcgct tggagaatgg gcattatgag attgatacgg ttctacttac
    22441 gagagcgaaa aactactgct tgcttgtctt gacggatcga aaaagtagac atcagatcat
    22501 ccgattgatt ccaaataaaa gtgctgaggt ggtcaatcag gctctaaaac tcatcttaaa
    22561 acaacacaag attctttcca tcacggcaga taatggaacg gaattcaatc gcttgtctaa
    22621 tgtattttct gaggagcaca tctattatgc gcacccctat gcctcttggg aaaggggaac
    22681 taatgagaat cacaacaggc tcattcatag atggttacct aagggaacca agaaaatgac
    22741 tcccaaagaa gtcgcattca tcgaaaagtg gattaacaac tatcctaaaa aatgcttgaa
    22801 ctacaagtca cccagagaag acttcttgat ggctaacttg aacttgaaat ttagcgtcag
    22861 aaacaaatca cgaaatcgat tcaaattttg caggtcgttt aaatatcctg cgcgcaggtg
    22921 ttcttggtgc taacgatgga attatttcca ttgctggtgt ggttatcggg gttgccagtg
    22981 ccacgaccaa tatctggatt atctttttat caggatttgc ggctatctta gctggtgcct
    23041 tttcaatggc tggtggagaa tatgtatccg tttcaactcc aaaagatacc gaggaagctg
    23101 ccgtttcgcg agaaaaactc ttgttagacc aagataggga actagccaaa aaatccctct
    23161 atgctgctta tatccaaaat ggagaatgca aaacttctgc ccaactcttg accaataaga
    23221 tctttcttaa aaatccactc aaggctctgg tagaggaaaa atatgggatt gagtatgaag
    23281 aatttaccaa tccttggcac gctgccattt ctagcttcgt tgcctttttc cttagaagtt
    23341 tgcctccaat gctgtcagtg accatattcc caagtgaata tcgcatccct gctactgtcc
    23401 ttattgtcgg tgtggccctt cttctcactg gttacactag tgccagactt ggaaaggatc
    23461 cgactagaac agctatgatt cggaaccttg ctattggtct cttgaccatg ggagttacct
    23521 tcctgctcga acaacttttc agcatttaga atacaagaaa tacctcgatt ttgaagtcga
    23581 ggtatctttt ttacatttgc acaatcttgc gataacttct tgaagtaatc atgaaaatca
    23641 gcacataggc gatgaggaag atagcgcaga tagacaaggt cacaatcaac atcatagtcg
    23701 tatccagtac accaatcact tttaaaatca ggctaagcat atggtaggca aaggcgagat
    23761 gtatgaaggc aaagagcaaa ggaaggaaga aaacagttaa aacctgtttg ttgatggttt
    23821 gcttgatttg cttttggtcc aaaccgactt tctgcaagat aataaagcgt tcacggtctt
    23881 cgtagccttc agaaatttgt ttgtagtaga tgaccagaac agttccgacc ataaagataa
    23941 tggataggaa aataccgata aagaagacac caccaaagag ggcactcatc tgagaactag
    24001 catctgctag attgctacca taaacatagc taccttctgt gtctaattga gcattaaatt
    24061 gattgaggta gttttcatac tcctcagcga ccttgagttg ttcttcttcg ctggcatcta
    24121 cattcatacc accgtaaaac tgattataga tagccgaatc tgggaattga tccaaaaagg
    24181 cttgtaaatc aggaacaaca aggtaattgt aatcagtagt caagatatta aacttatttg
    24241 gaacatggtt gacaatgaaa tctttattaa attcttcttt gacagaaaat tgatgatcat
    24301 ttagagttag agctttctgt cctttcagtc cgtcattttt ggcaaagaga ccgacctcat
    24361 ttcctgatag agacagtttt tgaccagtca tattttcata atctttttgg tcaaatacca
    24421 tgaaaactgt ttttggttgg acacggtttt gtcctttttc aaaaatagtt aacttggttc
    24481 cttcttgatt tgcaatacca aagttactgt aacgaagcac ttctttctct ttaatcttat
    24541 aacctttgtc acttgcaaac tggctcaaga gtttgtccaa atcttctttt tcaacatttt
    24601 gccctgaaac cccaaaatca tgaggattta gaactttttt aaaggattct gcggaattga
    24661 aaatgcttgt cgctgctgac atggttacca aaaccattgt tgacaaaata gcgatagttg
    24721 ctagtccaac tgcatttttc ttcatacgga aaatcaagtt agaaacagat atgagattat
    24781 taggttggta atagtatttc ttatttttct ttaagatttg aaggaaaacg gtaatccctg
    24841 cattgaacaa aagataagta ccaaagataa ccagtaaaac agctatgaag aaggttgtta
    24901 aggctgtaag aggatctttt accgtaaggg caagataata tccaatccct aaacttatgg
    24961 aaccaagaat agtttggaga ggaaggaagc gacctttttt ctctccgcta gctttctcac
    25021 gtgagagctg gagggcattc atacgggcga ttcgaagggc attcaggaac atgaggccta
    25081 ggaaaatcaa accgaagaca agaagtactg taatgacaac tttcatctgg aaggtagcga
    25141 ccagttccac cttcaatttc atcagtttga gtaggaaagc gaaaatcaac ttgtcaaaca
    25201 aggctccaat accgattcct gctccaacag ttagaatccc aaatagcact aactccttaa
    25261 aggtcatact gattagatgg cgcttctcca agcctaacat gccatatata cccagttcct
    25321 tggaacggtt tttcatgaca aaactattgg catagaggac gataatggct gacgcaaggg
    25381 taacgacaaa cataccaaat ccaagtgttg cttgaatggt ggttcctcca cggatttccg
    25441 caatcttggg attgaaggtt agggagtaaa agagataggt gatggtgact gccaagagaa
    25501 cagccagtgc aaagggatag tagagtttgc ggtttttaat caagttcgat accgctaact
    25561 tattggttaa tcgaaacata ctaattcacc tcgcttgcca tgacagtcaa ggtatcagag
    25621 atttcttgga acaactgacg ctctgtcttc tctccacggt agatttggtt gtaaagaatg
    25681 ccgtctttga taaagagaac acgcttggcc ctgctagcag ctgctgttga gtgggttacc
    25741 atgaggatgg tttgcccacg ctcattgatt tcattaaaga catcaagtaa ggttgcagat
    25801 gacttggaat caagggctcc tgttggctcg tccgcaagga gaatttcagg ttctgtgatg
    25861 atggcgcggg ctactgctac acgctgtttc tggccaccag aaatctcgta agggtacttc
    25921 tcttgcaatt ggttaatacc cagattctca gctgtcacca ccaatttctt catcatctcc
    25981 gttataggtc ttcttgacaa gacaagcgga agcaagatat tgtccttaac agacagagta
    26041 tctagcaagt taaagtcttg gaagacaaat cctagctttt cacgccggaa actagaagcc
    26101 tgtgaatttt taatagttgc ggtgtcagtt ccattcaagt aaacctgccc acgacttggt
    26161 ttatccaaca tagctagaat attgagaaga gttgatttac cagaaccaga ctcacccatg
    26221 atggcaacgt agtcaccctt ttctacggta aagtgaatat ccttgagggc ttctacttgg
    26281 ttgccctgaa aacgtgtttt ataaattttt tgaacgtgtt ttacatctaa aagtgtcatg
    26341 agaatctcct ttcttaatat cccatcaaat gaaatgtagc ttgcatcata gtgcatccca
    26401 gctgaacgcg ctcaatttct ttgtgacttg gttttctagt tttcttatgt aagatttgtt
    26461 tcatgatgtt actcctttgt tctttatgag tctagtttac atcaaaaaaa gaccgcttgc
    26521 cataacctaa ccttacaaaa gagactttaa tcttacattt ttgtaagatt gggtgaaata
    26581 taagcaaaat tacttagaaa atgatttgat ttcctatttt taaagttgta aaatataagt
    26641 gtgaaaaggc ttactttgaa aaggaggaag cgggaactaa cattttagta agcttaccta
    26701 gataacatac cattcaattt aacacttgca agtcgttcaa cctataagga aagaaggtgc
    26761 gctttaatga aacacaaaga acatatactc atcggacttc tctatctgct ctctccattc
    26821 atcggtcagc tcttagttga acacacacac tttatcagta cagaatttac cggcactgct
    26881 tatgttattt gctggttatc agttgttatc agcatccacc atttttccaa aaatgtattg
    26941 tctcaacagc aaaaatagat taaaaaactg cgtttaaatt actgctttta tagtaaaatg
    27001 aaataagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa ttttttagaa
    27061 gtataggtgt cctattctag ttccaatcca ctatagtttg tggatgaagc tggcgaaata
    27121 ttattaatac tattcaaaaa tcaaagtgca aactatatca acttcacatt gccgactaaa
    27181 ttacagcctg cggctggctt cctagtttgc actttgattt ttattgagta taaaagtaaa
    27241 aaagctttaa atcaagcagt ttagactatt gatttaaagc tttttgcgta ttccaaatct
    27301 tttgtaaaac ctcaccaaaa ccagccttca ttatcgtcaa tggcttgagc ttctttgcgt
    27361 ttacgtgggc ctgttccgta catttctgct tcgatttctt ccttggttgg catgatagaa
    27421 gctaggatga tatagataat caccccaagt ccaaagtttg cgactgtaaa aatggcaaac
    27481 agaaaacgta caagggtaac atcaaagttc cacttgtctg acagacctgc taaaactcct
    27541 gaaatcatgc gatttcgtct cattttataa aacttactgt tcatgatatt tcctctttct
    27601 gctaggttag actagtatat cacggatagg ctcggctttc atcagtcctc aggctgattt
    27661 actaatagca actttcctcg acaaagtcca cagcgatagc gttgggtatc aatcctacgc
    27721 ttacgctgat aagtttgctg gcaggattgg caacgataga gcttgattgg cttggagtta
    27781 ctattgggca aggatggtac aaaccgtaat ccatccactg ctttcaacag ttccttaaaa
    27841 tcccgatcct tgtgttgata gactttccct tgaaaataga ggtgataatg acagagttca
    27901 tgtcggacaa ttttcctaaa aacgtccaac cccagttcct gataaacctt gggattaaaa
    27961 tccaaatgcc catctttggg gaaaaatcgc ccacctgtcg aacgtagacg cctattccac
    28021 tggacatgat ggataaaagg tctgccgaag tcttctagtg aaacctgctt gacgtaatca
    28081 gtcagtttca tttggagcta ggagagacag attaactttt tcacgttcag tatcaatttt
    28141 cttaacccaa acgctcacca aatctccaac tgccaccact tgactagggt gtttgataaa
    28201 cttgcgactc atatgggaaa tatggatgag accgtcctca tgaattccga tatcaacaaa
    28261 agcaccgaaa tcaacaacat tacgcaccac tccttctagc ttttgtccaa ccactaagtc
    28321 cttgatatct aggacatctt gacggagaac tggagcatca aaggaatcac ggaaatctcg
    28381 acctggtttg agaagatctg caatgatatc tttaagagtt tctggaccaa ggtctaactc
    28441 ttgcgccatt tccttgactg aaagcgactt gagtttactt tgggcctctt cattcagatc
    28501 cttaatgtcc aagcatttga agagttcctt aacggcagcg taattttctg ggtgaactcc
    28561 tgtattatca aggatattgc tactttcagg gatacggagg aaaccagcag cctgttcaaa
    28621 agccttggcc cccaaacgag gaactttctt gatttgggag cgtgaagtga tttttccctc
    28681 ttcctcacgg tatttgacga tattttcaga aatggtttta ttgagtccag ctacgtgtga
    28741 aagaagagct gggctagctg tattgacatt gacaccaact tggttaacca ctgtatcgac
    28801 aacaaagtcc agactctcag atagtttctt ctgactgaca tcgtgttggt attgaccgac
    28861 accaattgac ttaggatcga ttttgaccaa ttccgcaaga ggatcttgca aacgacgggc
    28921 gatagaaatg gcagagcgtt tttcaacggt caagtctgga aactcctgac gagcaagttc
    28981 gctggcagaa tagacagaag caccactttc attaacgata acatagctga cttcagggaa
    29041 atctttcaga acttccgcta caaaagcttc actttcacga ctggccgttc catttccaat
    29101 ggcaataatc tctacaccgt attgaccaat taaatctgct aaatctttct tggcttcttc
    29161 gatttgacga gctgatgctg gtttaacagg ataaataacc tgagttgtca gcatttttcc
    29221 tgttgcatcc acgacagcta gcttggcacc tgtacgaaag gctgggtcaa acccaagaac
    29281 cacgcgccct ttcagtggag caaccaagag gagattgcgc agattgtcag aaaaaagttg
    29341 gatagctccc tcttcagctt tctcagttaa ttctgtccga atacgacgct caatagcagg
    29401 caagaccttt ttcttaacgg attgctgaac aacttcatca atataagcat ttttcacctt
    29461 gaaacgagta gcaaagaagg caagaatacg gtccgtcgca tgttcaaaac cgatcttcaa
    29521 gacaccaagt ttctccccac gattgagagc caaggtacga tagccttgca tagttccaac
    29581 tgtctctgaa aaatcataat aaatctgaaa aacctgcttt tcatcaagac tttcatcctt
    29641 ggcttgagaa gtgagtttag agtgtctcag cacttcctga taagtcatag aacgcaaggt
    29701 cacatcttcc gataaggctt cgaccaaaat atcaactgca ccggtcaagg cttccttgcc
    29761 agtcgcaaat ccttcacaga cgaacttttc agcttctttc tctaagtcaa ctatattctg
    29821 caaaatcaag cgagcaagag gaaagagtcc agcttcacgg gcaatggttg ccttggtacg
    29881 acgcttttcc ttataaggaa gatagagttc ttcaacgtct gctaattttt cggcaactaa
    29941 gatagcttct tccaattcct tggtcaactt accttgttct tgaatcttag ctaagacagc
    30001 ttccttacgg tcattgagat ttgtcagact tttatccaaa tcaataatag ccttaatcgc
    30061 cacctcatcc agactaccag tcatgtcctt gcgataacgc gcgataaagg gaatagtcgc
    30121 cccttcagct gtcaaactta gaacggtatc aatttgcttt aacgtcactc ccaaatcctg
    30181 agagattttt tcatattttt tatccataaa tctattatac cacaagctgg aaggctttct
    30241 ccaatccttt tcatactcaa taaaaatcaa aaagcaaact aggaagctag ccgtaggctg
    30301 ctcaaaa
//
LOCUS       DBEJJE010000028        25982 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEJJE010000028 DBEJJE010000000
VERSION     DBEJJE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.28"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            283..6699
                     /locus_tag="ACL3F5_001232"
     CDS             283..6699
                     /locus_tag="ACL3F5_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0515033.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSKDTEEKKATVIEEKEVVSKNPVIDTKTSNEEARIKEDSNQS
                     QGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFI
                     RGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYY
                     LVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFN
                     IHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTD
                     LEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATKY
                     DFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
     gene            7324..7800
                     /locus_tag="ACL3F5_001233"
     CDS             7324..7800
                     /locus_tag="ACL3F5_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0515034.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVCLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYAYIAEAIA"
     gene            7838..8143
                     /locus_tag="ACL3F5_001234"
     CDS             7838..8143
                     /locus_tag="ACL3F5_001234"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515035.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8191..9666
                     /locus_tag="ACL3F5_001235"
     CDS             8191..9666
                     /locus_tag="ACL3F5_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0515036.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9971..16672
                     /gene="bgaA"
                     /locus_tag="ACL3F5_001236"
     CDS             9971..16672
                     /gene="bgaA"
                     /locus_tag="ACL3F5_001236"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0515037.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNIVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKIF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLLVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAKLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16920..17366)
                     /locus_tag="ACL3F5_001237"
     CDS             complement(16920..17366)
                     /locus_tag="ACL3F5_001237"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515038.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYTHPDGWYYRFHHTKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKI
                     DVEPVFGQIKASLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(17531..17776)
                     /locus_tag="ACL3F5_001238"
     CDS             complement(17531..17776)
                     /locus_tag="ACL3F5_001238"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515039.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFDRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(17986..18345)
                     /locus_tag="ACL3F5_001239"
     CDS             complement(17986..18345)
                     /locus_tag="ACL3F5_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0515040.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            18456..19403
                     /locus_tag="ACL3F5_001240"
                     /pseudo
     CDS             18456..19403
                     /locus_tag="ACL3F5_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241739.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19387..19944
                     /locus_tag="ACL3F5_001241"
     CDS             19387..19944
                     /locus_tag="ACL3F5_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0515041.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19937..20191
                     /locus_tag="ACL3F5_001242"
     CDS             19937..20191
                     /locus_tag="ACL3F5_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515042.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20203..22257
                     /locus_tag="ACL3F5_001243"
     CDS             20203..22257
                     /locus_tag="ACL3F5_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0515043.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22436..23296
                     /locus_tag="ACL3F5_001244"
     CDS             22436..23296
                     /locus_tag="ACL3F5_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0515044.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23507..24217
                     /gene="ccdA2"
                     /locus_tag="ACL3F5_001245"
     CDS             23507..24217
                     /gene="ccdA2"
                     /locus_tag="ACL3F5_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0515045.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24237..24803
                     /locus_tag="ACL3F5_001246"
     CDS             24237..24803
                     /locus_tag="ACL3F5_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0515046.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24814..25926
                     /gene="msrB"
                     /locus_tag="ACL3F5_001247"
     CDS             24814..25926
                     /gene="msrB"
                     /locus_tag="ACL3F5_001247"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0515047.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         8483 a         4564 c         5493 g         7442 t
ORIGIN      
        1 tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa
       61 tcttattttt taatgtgtgc taaaaaataa attaatgcat gttaattttt cttgaattaa
      121 atttttttaa atgatatact gtatttatgg agagataaca attatatata aatgtactac
      181 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
      241 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
      301 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
      361 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
      421 aataaagaga aacatgaaga tatccatagt gctatggaaa cttcaaagga tactgaagaa
      481 aagaaagcaa cagttattga ggaaaaagaa gttgttagta aaaatcctgt gatagacact
      541 aaaactagca atgaagaagc aagaatcaaa gaagattcca atcaatccca aggagataat
      601 gcacactcgt ctgcaaataa aggcacagaa aatcccaaaa aagaagatag acttgtctat
      661 attgctgaat ttaaagataa agaatctgga gaaaaagcaa tcaaggaact atccagtctt
      721 aagaatacaa aagttttata tacttatgat agaattttta acggtagtgc catagaaaca
      781 actccagata acttggacaa aattaaacaa atagaaggta tttcatcgat tgaaagggca
      841 caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa ttggagttga ggaagctatt
      901 gattacctaa agtctatcaa tgctccgttt gggaaaaatt ttgatggtag aggtatggtc
      961 atttcaaata tcgatactgg aacagattat agacataagg ctatgagaat cgatgatgat
     1021 gccaaagcct caatgagatt taaaaaagaa gacttaaaag gcactgataa aaattattgg
     1081 ttgagtgata aaatccctca tgcgttcaat tattataatg gtggcaaaat cactgtagaa
     1141 aaatatgatg atggaaggga ttattttgac ccacatggga tgcatattgc agggattctt
     1201 gctggaaatg atactgaaca agacatcaaa aactttaacg gcatagatgg aattgcacct
     1261 aatgcacaaa ttttctctta caaaatgtat tctgacgcag gatctgggtt tgcgggtgat
     1321 gaaacaatgt ttcatgctat tgaagattct atcaaacaca acgttgatgt tgtttcggta
     1381 tcatctggtt ttacaggaac aggtcttgta ggtgagaaat attggcaagc tattcgggca
     1441 ttaagaaaag caggcattcc aatggttgtc gctacgggta actatgcgac ttctgcttca
     1501 agttcttcat gggatttagt agcaaataat catctgaaaa tgaccgacac tggaaatgta
     1561 acacgaactg cagcacatga agatgcgata gcggtcgctt ctgctaaaaa tcaaacagtt
     1621 gagtttgata aagttaacat aggtggagaa agttttaaat acagaaatat aggggccttt
     1681 ttcgataaga ataaaatcac aacaaatgaa gatggaacaa aagctcctag taaattaaaa
     1741 tttgtatata taggcaaggg acaagaccaa gatttgatag gtttggatct taggggcaaa
     1801 attgcagtaa tggatagaat ttatacaaag gatttaaaaa atgcttttaa aaaagctatg
     1861 gataagggtg cacgcgccat tatggttgta aatactgtaa attactacaa tagagataat
     1921 tggacagagc ttccagctat gggatatgaa gcggatgaag gtactaaaag tcaagtgttt
     1981 tcaatttcag gagatgatgg tgtaaagcta tggaacatga ttaatcctaa taaaaaaact
     2041 gaagtcaaaa gaaataataa agaagatttt aaagataaat tggagcaata ctatccaatt
     2101 gatatggaaa gttttaattc caacaaaccg aatgtaggtg acgaaaaaga gattgacttt
     2161 aagtttgcac ctgacacaga caaagaactc tataaagaag atatcatcgt tccagcagga
     2221 tctacatctt gggggccaag aatagattta cttttaaaac ccgatgtttc agcacctggt
     2281 aaaaatatta aatccacgct taatgttatt aatggcaaat caacttatgg ctatatgtca
     2341 ggaactagta tggcgactcc aatcgtggca gcttctactg ttttgattag accgaaatta
     2401 aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg gagatgacaa aatagacctt
     2461 acaagtctta caaaaattgc cctacaaaat actgcgcgac ctatgatgga tgcaacttct
     2521 tggaaagaaa aaagtcaata ctttgcatca cctagacaac agggagcagg cctaattaat
     2581 gtggccaatg ctttgagaaa tgaagttgta gcaactttca aaaacactga ttctaaaggt
     2641 ttggtaaact catatggttc catttctctt aaagaaataa aaggtgataa aaaatacttt
     2701 acaatcaagc ttcacaatac atcaaacaga cctttgactt ttaaagtttc agcatcagcg
     2761 ataactacag attctttaac tgacagatta aaacttgatg aaacatataa agatgaaaaa
     2821 tctccagatg gtaagcaaat tgttccagaa attcacccag aaaaagtcaa aggagcaaat
     2881 atcacatttg agcatgatac tttcactata ggcgcaaatt ctagctttga tttgaatgcg
     2941 gttataaatg ttggagaggc caaaaacaaa aataaatttg tagaatcatt tattcatttt
     3001 gagtcagtgg aagaaatgga agctctaaac tccaacggga agaaaataaa cttccaacct
     3061 tctttgtcga tgcctctaat gggatttgct gggaattgga accacgaacc aatccttgat
     3121 aaatgggctt gggaagaagg gtcaagatca aaaacactgg gaggttatga tgatgatggt
     3181 aaaccgaaaa ttccaggaac cttaaataag ggaattggtg gagaacatgg tatagataaa
     3241 tttaatccag caggagttat acaaaataga aaagataaaa atagaacatc tctagatcaa
     3301 gatccagact tatttgcctt taacaaccaa ggtgttcatg cagaatccac tagtggttct
     3361 aagattgcta acatttatcc tttagattca aatggaaatc ctcaagatgc tcaactagaa
     3421 agaggactaa ctccatctcc acttgttcta agaagtgcag aagaaggact aatttcaatt
     3481 gtaaacacca acaaagaagg agaaaaccaa aaagacctta aagttgtatc aagagagcac
     3541 ttcataagag gaattctaaa ttctaaggga aatgacgcta agggtatcaa atcatccaaa
     3601 ctaaaagttt ggggtgactt gaaatgggat ggactcatct ataacccaag aggtagagaa
     3661 gaaaatgccc cagaaagtaa ggataaccaa gatccagcta ctaagatacg aggacaattt
     3721 gaaccgattg cggaaggtca atatttctat aaatttaaat atagattaac taaagattac
     3781 ccatggcagg tttcctatat tcctgtaaaa attgataaca cagcccctaa gattgtttcg
     3841 gttgattttt caaatcctga aaaaattaag ctaatcacaa aggatactta tcacaaggta
     3901 aaagatcaat acaagaatga aactttattt gctagagatc aaaaagaaca tcctgaaaaa
     3961 tttgatgaga ttgcaaatga ggtgtggtat gcaggagctg ctcttgttaa tgaagatgga
     4021 gaggttgaga aaaatcttga agtaacttat gcaggtgagg gtcaaggaag aaataggaag
     4081 cttgataaag atgggaatac tatctatgaa attagcggag caggagatct aagaggaaaa
     4141 atcatcgaag taatcgccct agatggagca agcaacttta ccaaaatcca taggattaaa
     4201 tttgctaatc aagctgatga aaaagggatg atttcctatt atctagtaga tcctgatcag
     4261 gattcatcta aataccaaaa gcttggcgaa attcctgaat ctaaatttaa gaatttaaaa
     4321 aatgttaaag atgatagcct aaacaaagag acagctgagg tggaaaataa ccttttagta
     4381 gataatcagt ctatcgaagg aaaatctctc tttaatattc ataaaactat ttcaacaatt
     4441 agagactttg aaaataaaga cctaaagaaa ctcattaaaa agaaatataa gcaagaagac
     4501 gactttgtaa atggtggaac aagaacagta gagcgtgatt ataaatacga tgataaagga
     4561 aatataatag cctacgatga tgggactgat ctagaatatg aaactgagaa acttgacgaa
     4621 atcaaatcaa aaatttatgg tgttctaagt ccgtctaaag atggacactt tgaaattctt
     4681 ggaaagataa gtaatgtttc taaaaatgcc aaggtatatt atgggaataa ctataaatct
     4741 atagaaatca aagcgaccaa gtatgatttc cactcaaaaa cgatgacatt tgatctatac
     4801 gctaatatta atgatattgt ggatggatta gcttttgcag gagatatgag attatttgtt
     4861 aaagataatg atcagaaaaa agctgaaatt aaaattagaa tgcctgaaaa aattaaggaa
     4921 actaaagcag aatatcccta tgtatcaagt tatgggaatg tcatagaatt aggggaagga
     4981 gatctttcaa aaaacaaacc agacaattta actaaaatgg aatctggtaa aatctattct
     5041 gattcagaaa aacaacaata tctgttaaag gataatatca ttctaagaaa aggctatgca
     5101 ctaaaagtga ctacctataa tcctggaaaa acggatatgt tagaaggaaa tggagtctat
     5161 agcaaggaag atatagcaaa aatacaaaag gccaatccta atctaagagc cctttcagaa
     5221 acaacaattt atgctgatag tagaaatgtt gaagatggaa gaagtaccca atctgtatta
     5281 atgtcggctt tggacggctt taacattata aggtatcaag tgtttacatt taaaatgaac
     5341 gataaagggg aagctatcga taaagacgga aatcttgtga cagattcttc taaacttgta
     5401 ttatttggta aggatgataa agaatacact ggagaggata agttcaatgt agaagctata
     5461 aaagaagatg gctccatgtt atttattgat accaaaccag taaacctttc aatggataag
     5521 aactacttta atccatctaa atctaataaa atttatgtac gaaatccaga attttattta
     5581 agaggtaaga tttctgataa gggtggtttt aactgggaat tgagagttaa tgaatcggtt
     5641 gtagataatt atttaatcta cggagattta cacattgata acactagaga ttttaatatt
     5701 aagctgaatg ttaaagacgg tgacatcatg gactggggaa tgaaagacta taaagcaaac
     5761 ggatttccag ataaggtaac agatatggat ggaaatgttt atcttcaaac tggctatagc
     5821 gatttgaatg ctaaagcagt tggagtccac tatcagtttt tatatgataa tgttaaaccc
     5881 gaagtaaaca ttgatcctaa gggaaatact agtatcgaat atgctgatgg aaaatctgta
     5941 gtctttaaca tcaatgataa aagaaataat ggattcgatg gtgagattca agaacaacat
     6001 atttatgtaa atggaaaaga atatacatca tttgatgata ttaaacaaat aacagacaag
     6061 acactaaaca ttaagattgt tgtaaaagat tttgcaagaa atacaaccgt aaaagaattc
     6121 attttaaata aagatacggg agaggtaagt gaattaaaac ctcatagggt aactgtgacc
     6181 attcaaaatg gaaaagaaat gagttcaacg atagtgtcgg aagaagattt tattttacct
     6241 gtttataagg gtgaattaga aaaaggatac caatttgatg gttgggaaat ttctggtttc
     6301 gaaggtaaaa aagacgctgg ctatgttatt aatctatcaa aagatacctt tataaaacct
     6361 gtattcaaga aaatagagga gaaaaaggag gaagaaaata aacctacttt tgatgtatcg
     6421 aaaaagaaag ataacccaca agtaaaccat agtcaattaa atgaaagtca cagaaaagag
     6481 gatttacaaa gagaagatca ttcacaaaaa tctgattcaa ctaaggatgt tacagctaca
     6541 gttcttgata aaaacaatat cagtagtaaa tcaactacta acaatcctaa taagttgcca
     6601 aaaactggaa cagcaagcgg agcccagaca ctattagctg ccggaataat gtttatagta
     6661 ggaatttttc ttggattgaa gaaaaaaaat caagattaag acaaaagcta tagaaaaaat
     6721 ggtttatgta ctgagattag atagtgaggt gatgacatag ttttgtgaaa acagccattt
     6781 ataactcaat tatttagttt acttcactat tgatactatt tggagttatt aatggactta
     6841 gtttagataa ctaatgaatt gattgaaagg gttagtattg acaatattgg tcatattgat
     6901 tagaaaatag agtctatcaa aatttaaagg ctaatagagg tgatgagaca atttcaagga
     6961 attaagtagc gtttggttgc ttaattcctt tttatttgga aggaagtttt tcgtaaccgc
     7021 ccaataacga agtctattgg acggttacga tatgatcact gacttcgtca gtcttatcta
     7081 caacctcaaa actgtgtttt gagcaacctg cggctagctt cctagtttac tctttgattt
     7141 tcattgagta ttagaacaga aaaaatgctt ggagtatttg tttgtgtgtt tatttttaca
     7201 taacaaacta taaacaaaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat
     7261 tgacaacggt ttcatatagt gttatactta tggcataaag ttaatggaaa gaagggaaaa
     7321 cttatggtat tagattattt ctttgacaaa aaccttgtgt tttgcttaga agcggataat
     7381 caagaacaac tctttgatca ggttgcaact ttattggaag aacgagaaat tgtcactcca
     7441 acttatcgtg aagccttgat cacgcgtgaa aagtcatttc caactggttt agatatggaa
     7501 tttctaggaa aggacttgcc aaatgtagcg attcctcata cagatattgt tcataatcta
     7561 gctgagaaag tggtggttgt tcgattagag aaaccagtaa cttttcacaa tatgatagct
     7621 cctgataagg aagtagaagt atgcttactc ttctttatca tcaataattc aagttcaagt
     7681 caaacgaaca ttcttgctca gttgatggac ttcttcacag gaaatggtca tcttgaagac
     7741 ctatcaaaaa tttctgaacc agaagccctt tatgcttata tagctgaagc aatcgcttaa
     7801 tcttgtctat taaaaaataa aatcggagga aatccaaatg attaaaattc ttgctgcctg
     7861 cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct ctagaagaag aactttcaaa
     7921 ccgtggttat gatgttcact gtgatgcagt catggtgaaa gatgtaaacg aagaccttat
     7981 gaaaggttac gatatcttta caccaatcgc tgcaacagat cttggttttg aaccaggtat
     8041 cccagttatc gaagctgggc caatcttatt ccgtatacca gcaatgagcg ctccagtatt
     8101 tgacaatatt gaagcagcta ttaaagaaca cggattaagc taattctaat ttgttaacat
     8161 tcatataaca taaaaaaggg aggaactgtt atggatgcaa tctttgacct aatcggaaag
     8221 gttttcaatc ccatcttaga aatgggtgga cctgtcatca tgttaatcat tttgacagta
     8281 ttggctttac tttttggagt gaaattctcc aaagcgcttg aaggtggtat caaacttgcc
     8341 atcgctctta caggtatcgg tgctatcatc ggtatgctaa atggtgcttt ctcagcatca
     8401 cttgcaaaat tcgttgaaaa cactggtata caattgagta ttaccgacgt tggttgggca
     8461 ccactcgcaa caatcacttg gggttctgct tggacacttt acttcttgct catcatgttg
     8521 attgtcaacg tagtgatgct tgctatgaag aaaaccgata cacttgatgt cgatatcttt
     8581 gatatctggc acttgtctat cacaggtctc ttgattaaat ggtatgctga taacaatggt
     8641 gtgagtcaag gggtttcact cttgattgct acagcagcta tcgttcttgt cggtgtgttg
     8701 aaaattatca actctgactt gatgaaacct acatttgatg accttcttaa cgccccaagt
     8761 tcatcaccaa tgacatcaac tcacatgaac tacatgatga acccagttat catggttttg
     8821 gataagattt ttgaaaaatt cttcccaggc cttgataaat atgactttga tgctgctaaa
     8881 ttgaacaaga aaatcggttt ctggggatct aaattcttca tcggtttcat ccttggtatc
     8941 gttatcggta ttatgggaac tccacatcca attgcaggtg ttgcagatgc agataaatgg
     9001 cgtcttgtta tcaaaggatg gttgtctctt ggtttgactg ccggtgtatc tttggaactc
     9061 ttctcactta tcggttcatg gttcatcgca gccgtagaac cactatcaca aggtattaca
     9121 aacgttgcta ctaaacgtct tcaaggacgt aaattcaata tcggtcttga ctggccattc
     9181 atcgctggtc gtgctgaaat ctgggcttgt gccaacgtac ttgcaccaat catgttgatt
     9241 gaagcagtgc ttctttcaaa agttggaaat ggtatcttgc cacttgcagg tatcatcgct
     9301 atgggtgtta ctccagctct cttggttgta actcgtggta aattgctccg tatgattatc
     9361 ttcggaacac tcttgttgcc actcttcctt ctttcaggta cccttattgc accatttgca
     9421 acagaacttg ctaaaggtgt aggtgccttc ccagaaggtg tgagccaaac tcaattgatt
     9481 actcactcta ctcttgaagg accaatcgaa aaacttcttg gttggacaat tggtaacact
     9541 acaactggtg atatcaaagc aatccttggt gcagtagcct tccttgtatt ctatatcggt
     9601 atctttgctt ggtacagaaa acaaatgatc aaacgtaacg aagagtacgc agcaaaagca
     9661 aaataatgcg ctcctataaa atataaactc aatgaaaatc aaagagcaaa ctaggaagct
     9721 agccgcaggt tgctcaaaac acagttttga ggttgtagat aagactgact aagtcagctc
     9781 aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaatcata tctacggcaa
     9841 ggcgacactg acgaagtttg aattggattt tcgcagagtg taaattgttg aaactaggtt
     9901 gtcataccat gtataccact tgggctttgg tagtagctaa ctgcactaaa tataatataa
     9961 ggagggtttt atggggaaag gccattggaa tcggaaaaga gtttatagca ttcgtaagtt
    10021 tgctgtggga gcttgctcag taatgattgg gacttgtgca gttctattag gaggaaatat
    10081 agctggagaa tctgtagttt atgcggatga aacacttatt actcatactg ctgagaaacc
    10141 taaagaggaa aaaatgatag tagaagaaaa ggctgataaa gctttggaaa ctaaaaatat
    10201 agttgaaagg acagaacaaa gtgaacctag ttcaactgag gctattgcat ctgagaagaa
    10261 agaagatgaa gccgtaactc caaaagagga aaaagtgtct gctaaaccgg aagaaaaagc
    10321 tccaaggata gaatcacaag cttcaaatca agaaaaaccg ctcaaggaag atgctaaagc
    10381 tgtaacaaat gaagaagtga atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa
    10441 ttggtacttt aaactcaatg caaattctaa ggaagccatt aaacctgatg cagacgtatc
    10501 tacgtggaaa aaattagatt taccgtatga ctggagtatc tttaacgatt tcgatcatga
    10561 atctcctgca caaaatgaag gtggacagct caacggtggg gaagcttggt atcgcaagat
    10621 tttcaaacta gatgaaaaag acctcaagaa aaatgttcgc cttacttttg atggcgtcta
    10681 catggattct caagtttatg tcaatggtca gttagtgggg cattatccaa atggttataa
    10741 ccagttctca tacgatatca ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc
    10801 tgtccatgca gtcaacaaac agccaagtag ccgttggtat tcaggaagtg gtatctatcg
    10861 tgatgtgact ttacaagtga cagataaggt gcatgttgag aaaaatggga caactatttt
    10921 aacaccaaaa cttgaagaac aacaacatgg caaggttgaa actcatgtga ccagcaaaat
    10981 cgtcaatacg gacgacaaag accatgaact tgtagccgaa tatcaaatcg ttgaacgagg
    11041 tggtcatgct gtaacaggct tagttcgtac agcgagtcgt accttaaaag cacatgaatc
    11101 aacaagccta gatgcgattt tagaagttga aagaccaaaa ctctggaccg ttttaaatga
    11161 caaacctgcc ttgtacgaat tgattacgcg tgtttaccgt gacggtcaat tggttgatgc
    11221 taagaaggat ttgtttggtt accgttacta tcactggact ccaaatgaag gtttctcttt
    11281 gaatggtgaa cgtattaaat tccatggagt atccttgcac cacgaccatg gggcgcttgg
    11341 agcagaagaa aactataaag cagaatatcg ccgtctcaaa caaatgaagg agatgggagt
    11401 taactccatc cgtacaaccc acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga
    11461 actaggttta ctcgttcagg aagaggcctt tgatacgtgg tatggtggca agaaacctta
    11521 tgactatgga cgtttctttg aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa
    11581 atggtctgat tttgacctac gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt
    11641 catgtggtca attggtaatg aaataggtga agctaatggt gatgcccact ctttagcaac
    11701 tgttaaacgt ttggtcaagg ttatcaagga tgttgataag actcgctatg ttaccatggg
    11761 agcagataaa ttccgtttcg gtaatggtag cggagggcat gagaaaattg ctgatgaact
    11821 cgatgctgtt ggatttaact attctgaaga taattacaaa gcccttagag ctaagcatcc
    11881 aaaatggttg atttatggat cagaaacatc ttcagctacc cgtacacgtg gaagttacta
    11941 tcgccctgaa cgtgaattga aacatagcaa tggacctgag cgtaattatg aacagtctga
    12001 ctatggtaat gatcgtgttg gttgggggaa aacagcaacc gcttcatgga cttttgaccg
    12061 tgacaacgct ggctatgctg gacagtttat ctggacaggt acggactata ttggtgaacc
    12121 tacaccatgg cacaaccaaa atcaaactcc tgttaagagc tcttactttg gtatcgtaga
    12181 tacagccggc attccaaaac atgacttcta cctctaccaa agccaatggg tttctgttaa
    12241 gaagaaaccg atggtacacc ttcttcctca ctggaactgg gaaaacaaag aattagcatc
    12301 caaagtagct gactcagaag gtaagattcc agttcgtgct tattcgaatg cttctagtgt
    12361 agaattgttc ttgaatggaa aatctcttgg tcttaagact ttcaataaaa aacaaaccag
    12421 cgatgggcgg acttaccaag aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt
    12481 tgcctatcaa ccgggtacct tggaagcaat tgctcgtgat gaatctggca aggaaattgc
    12541 tcgagataag attacgactg ctggtaagcc agcggcagtt cgtcttatta aggaagacca
    12601 tgcgattgca gcagatggaa aagacttgac ttacatctac tatgaaattg ttgacagcca
    12661 ggggaatgtg gttccaactg ctaataatct ggttcgcttc caattgcatg gccaaggtca
    12721 actggtcggt gtagataacg gagaacaagc cagccgtgaa cgctataagg cgcaagcaga
    12781 tggttcttgg attcgtaaag catttaatgg taaaggtgtt gccattgtca aatcaactga
    12841 acaagcaggg aaattcaccc ttactgccca ctctgatctc ttgaaatcga accaagtcac
    12901 tgtctttact ggtaagaaag aaggacaaga gaagactgtt ttggggacag aagtgccaaa
    12961 agtacagacc attattggag aggcacctga aatgcctacc actgttccgt ttgtatacag
    13021 tgatggtagc cgtgcagaac gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg
    13081 tattgtaacg gtgaaaggta tggctgacgg acgagaagta gaagctcgtg tagaagtgat
    13141 tgctcttaaa tcagagctac cagttgtgaa acgtattgct ccaaatactg acttgaattc
    13201 tgtagacaaa tctgtttcct atgttttgac tgatggaagt gttgaagagt atgaagtgga
    13261 caagtgggag attgccgaag aagataaagc taagttagca attccaggtt ctcgtattca
    13321 agcgaccggt tatttagaag gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa
    13381 tcctgcggca cctgcagtac caactgtaac ggttggtggt gaagctgtca caggtcttac
    13441 tagtcaaaaa ccaatgcaat accgcactct tgcttatgga gctaagttgc cagaagtcac
    13501 agcaagtgct aaaaatgcag ctgttacagt tcttcaagca agcgcagcaa acggcatgcg
    13561 tgcgagcatc tttattcagc ctaaagatgg tggccctctt caaacctatg caattcaatt
    13621 ccttgaagaa gcgccaaaaa ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct
    13681 caaagaagac caaactgtca aattgttggt tcgagctcac tatcaagatg gaacgcaagc
    13741 tgtattacca gctgataaag taaccttctc tacaagtggt gaaggggaag tcgcaattcg
    13801 taaaggaatg cttgagttac ataagccagg agcagtcact ctcaaagcgg aatatgaggg
    13861 agctaaaggc caagttgatc tcactatcca ggccaatact gagaagaaga ttgcgcaatc
    13921 tatccgtcca gtaaatgtag tgacagattt acaccaagaa cctactcttc cgtcaacagt
    13981 aacggttgag tatgacaaag gtttccctaa agctcacaaa gtcacttggc aagctattcc
    14041 gaaagaaaaa ctagactcct atcaaacctt tgaagtacta ggtaaagttg aaggaattga
    14101 ccttgaagcg cgtgcaagag tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt
    14161 gacaactcca atcgcagaag caccacaatt accagaaagc gttcggacat atgattcaaa
    14221 tggtcacgtt tcatcagcta aggttgcatg ggatgcgatt cgtatagagc aatacgctaa
    14281 ggaaggtgtc tttacagtta atggtcgctt agaaggtact caattaacaa ctaaacttca
    14341 tgttcgcgta tctgctcaaa ctgagcaagg tgcaaacatt tctgaccaat ggaccggttc
    14401 agaattgcca cttgcctttg cttcagattc aaatccaagc gacccagttt caaatgttaa
    14461 tgacaagctc atttcctaca ataaccaacc agccaatcgt tggacaaact ggaatcgtag
    14521 taatccagaa gcttcagtcg gtgttctgtt tggagattca ggtatcttga gcaaacgctc
    14581 cgttgataat ctaagtgtcg gattccatga agaccatgga gttggtgcac cgaagtctta
    14641 tgtgattgag tattatgttg gcaagactgt cccaacagct cctaaaaacc ctagttttgt
    14701 tggtaatgag gaccatgtct ttaatgattc tgccaactgg aaaccagtta ctaatctaaa
    14761 agcccctgct aaactcaagg ctggagaaat gaaccacttt agctttgata aagttgaaac
    14821 ctatgctatt cgtattcgca tggttaaagc agataacaag cgtggaacgt ctatcacaga
    14881 ggtacaaatc tttgcgaaac aagttgcggc agccaaacaa ggacaaacaa gaatccaagt
    14941 tgacggcaaa gacttagcaa acttcaaccc tgatttgaca gactactacc ttgagtctgt
    15001 agatggaaaa gttccggcag tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt
    15061 tccaagcgtt cgtgaaggtg agccagttcg tgtcatcgcg aaagctgaaa atggcgacat
    15121 cttaggagaa taccgtctgc acttcactaa ggataagaac ttactttctc ataaaccagt
    15181 tgctgcggtt aaacaagctc gcttgctaca agtaggtcaa gcacttgaat tgccgactaa
    15241 ggttccagtt tacttcacag gtaaagacgg ctacgaaaca aaagatttgt cagttgaatg
    15301 ggaagaagtt ccagcagaaa atctgacaaa agcaggtcaa tttaccgttc gaggccatgt
    15361 ccttggtagt gatcttgttg ctgaggtcac tgtacgagtg acagacaaac taggcgaagc
    15421 tctttcagat aaccctaact atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa
    15481 tgatattgac aaaaactctc atgaccgcgt tgactatctc aatgacggag atcattcaga
    15541 aaatcgtcgt tggacaaact ggtctccaac accatcttct aatccagaag tatcagcggg
    15601 tgtgatcttc cgtgaaaatg gtaagattgt agaacggact gttgcgcaag ccaaacttca
    15661 cttctttgca gatagtggta cggatgcacc aactaaactc gttttagaac gctatgtcgg
    15721 tccagagttt gaagtgccaa cctactattc aaactaccaa gcctacgacg cagaccatcc
    15781 attcaacaat ccagaaaatt gggaagctgt gccttatcgt gcggataaag acattgaagc
    15841 cggtgatgaa atcaacgtaa catttaaagc tgtcaaagcc aaagccatga gatggcgtat
    15901 ggagcgtaaa gcagataaga gcggtgttgc gatgattgag atgaccttcc ttgcaccgag
    15961 tgaattgcct caagaaagca ctcaatcgaa gattcttgta gatggaaaag agcttgctga
    16021 tttcgctgaa aatcgtcaag actatcaaat tacctataaa ggtcaacggc caaaagtctc
    16081 agttgaagaa aataatcaag tagcttcaac tgtggtagat agtggagaag atagccttcc
    16141 agtacttgtt cgcctcgttt cagaaagtgg aaaacaagtc aaggaatacc gtatccactt
    16201 gactaaggaa aaaccagttt ctgagaagac agttgctgct gtacaagaag atcttccaaa
    16261 actcgaattt gttgaaaaag atttggccta caagacagtt gagaaaaaag attcaacact
    16321 gtatctaggt gaaactcgtg tagaacaaga aggaaaaact ggtaaagaac gtatctttac
    16381 agcgattaat cctgatggaa gtaaggaaga aaaactccgt gaagtggtag aagctccgac
    16441 agaccgcatc gtcttggttg gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt
    16501 gtcagaaaaa gcagatacaa aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc
    16561 ccagttacca aatacaggta gtgcgtcaag ccaagcagca gtagcagcag gtttagctct
    16621 tctaggtttg agtgcaggat tagtagttac taaaggtaaa aaagaagact agaaattttg
    16681 ataccttctt tatcattaaa gaccaaagaa aaactcttgt cctaaataga agataaagag
    16741 tctggaacaa aatagttctc aaccacaaaa aagctagata tttccaattg cggaactcta
    16801 gctttttaat tttgagtcgt tctcttattg tatagtagat tgaaactaga gtagtacact
    16861 tctacttcta aaacattgtt agaaatcgat ttgactgtcc ttatcgattt gtcctggtct
    16921 tatttcattt cactatgttt taggaggtta ttggccataa gtaccaatcc catgtcaatt
    16981 ctcacttgac gcttgcctct cagattacat ctcttgtaac ccaaagaagc ctttatctgt
    17041 ccaaagacag gttccacatc aatcttgcgt tgagcgaaaa tctgtctacc ttggggagat
    17101 aaaagcgcct gacattcttt agctttcaag ttttgatagc gttcgttcat atacagtccc
    17161 ttttgagggg ctgattcagg ttcgtcggcg tagtaaacct tgatttcttg ttgaaagtct
    17221 gtctgtgttt tctgatattt ggtatggtga aaacgataat accagccatc aggatgtgta
    17281 tagctatcct ccttgtcatt atagtgccaa ttcgctaagt ttttagctga ctgtttatac
    17341 cctctctttt gttccttatc aaacatggca tatttaatca ggaggggagt gatttcttct
    17401 tgaaaataga cttgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc
    17461 cacacaaaac tatacttgtt ggcattggct tcaatcttag ttccgtcaat aaacaaacaa
    17521 tctaaggtca ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat
    17581 aggcaaatag aagagtagat acaagcattt tagggtgata agacgggcga tcaaaggcat
    17641 gataggaggt gtagaagtga cgttcctcca aggtattcac cactttttca atagtaaaga
    17701 cgagatggtc ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt
    17761 tatagtgaat atgcatggga tagcctttct aaatggttta ttaagcaatt ctattttacc
    17821 aagactatcg taaccatgca aaaaagcaac ggcaaatccg ttgccttttt ggatataaga
    17881 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
    17941 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
    18001 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
    18061 gaatttgatg aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
    18121 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
    18181 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
    18241 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagatga ctaaggtcag
    18301 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
    18361 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
    18421 ggtgattttt gttataatga aagttataaa atcttataat accttataat accttgaatg
    18481 attattatcg aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg
    18541 actgtcccaa tcgtgatgga actgtggctc atggaggttg tactttttgt acggtttcag
    18601 gttctggaga tgctattgta gccccagatg cgcctatccg tgagcaattt tataaggaaa
    18661 ttgactttat gcaccgtaag tggccggatg ttcagaagta tctggtttat tttcaaaatt
    18721 ttaccaacac ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg
    18781 agccaggtgt ggtaggtatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca
    18841 tcgaatattt ggctgagtta tcggagtgca tgcatgtgat ggttaaattg ggcttgtaga
    18901 ctacttatga agcaacttct gacctgatta accgtgcgta ttcttatgaa ttgtaggtgg
    18961 aaacggtcaa gcgtttgaga aagtatccca agattgagat tgtttcccat ttgatcaatg
    19021 gtttgcctgg tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacgaata
    19081 acgatattca agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac
    19141 gagattacca tgagggacgt ttacaattga tgagtcagga cgaatatatc agggtcatct
    19201 gtgaccaact ggaaatcatt cccaaacata tcgtcatcca tcgaatcaca ggagatgcac
    19261 ctagggatat gctgcttggg cttatgtgga gcctcaataa atgggaagct ctcaacagca
    19321 ttgagatgga gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt
    19381 ttgaaaatga aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa
    19441 gaggatgtcg tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag
    19501 ctagccaagc aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag
    19561 cgtttgcatc aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg
    19621 gaccagtttg tgacaaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct
    19681 gataagtctg tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc
    19741 ttacttgtca aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat
    19801 ctcgagagag atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct
    19861 gccatttacc gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa
    19921 ttagagagat acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca
    19981 gaattttgtt gaatcaaccc accacgaacg agcggtgggc gtgctagacc aagcgcatat
    20041 gagcaaaaaa atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca
    20101 gagaaaaatt gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga
    20161 gatatttgaa tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac
    20221 ctcatcctat ttttactggt cttgattgtc tcaagtacaa ccaataagct cctacccttt
    20281 ttgcctctcc ctttggttca gattcttttg ggaattgtga ttggtctctt tttacccaat
    20341 actgactttc accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc
    20401 cgagaggctg aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat
    20461 ctcatatttc cagtgatttt tatctcgacc ctgagtttgg gtggcttggc ccatcttctt
    20521 tggttcagcc ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac
    20581 ttggtggcct ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt
    20641 cttaagggcg aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg
    20701 acagcttgga caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca
    20761 attctaggcg gttttttaat tggattttta acagctatga ccaaccgctt cctccatacc
    20821 ttcttgctaa gtgtgcgcgc aacggatatt gccagtgaac ttttattaga gttgagtttg
    20881 cctctagtga ccttctttct ggcagaagaa gtccatgttt cagggattat tgccgtcgta
    20941 gttgctggaa ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg
    21001 gatacggtga ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt
    21061 gtgattttag ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat
    21121 aatcctctac ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt
    21181 tttattatga tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat
    21241 aagtatatga aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt
    21301 gctacgattc tcttgatacc aagtaatcta gaacaggagt atcctctctt gcttttcctt
    21361 gttgcaggtg tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct
    21421 gatgaagagg aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg
    21481 ctagagttgg aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt
    21541 gacaattatc atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa
    21601 gaagactggg ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag
    21661 gcctatgaag aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa
    21721 aatatagaac aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt
    21781 tccttgagga ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt
    21841 agctggaagg acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag
    21901 ctctatcttg ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac
    21961 agacgctctt tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc
    22021 agtggtgcct ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg
    22081 ctgagaggct attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt
    22141 acgactaagt atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg
    22201 aaggaagctg ccaataccct accgtatgat atggtggaat tggtaagaag aaattagtta
    22261 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatgtgactg
    22321 acttcgtcag tcttatctac aacctcaaaa cagtgttttg agcagcttgc ggctagcttt
    22381 ctagtttgct ctttgatttt cattgagtat aagattataa gtgaaggagt atgacatgaa
    22441 aaagtggtgg aaagagctga tagacaaacc tttattaaaa gcttttttgc attattatca
    22501 agcatcagat agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt
    22561 ccccctgctt ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt
    22621 tctgggcttt atgaaagacg tcctgccccc aagcctctat gaaggtgtgg aaaaaatagc
    22681 cagagaagtc ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt
    22741 atggagtttt tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt
    22801 cgaaaagagt cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt
    22861 gcagctcctc tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt
    22921 acttgctcat tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg
    22981 tcctctgatt tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa
    23041 tctatctaac aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat
    23101 tttaggttta ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga
    23161 tgtccgaatt ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc
    23221 taaaattgtt atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt
    23281 ctttaaaaaa gactaactat ttatccatta taaaagcgca tagtatcaag actttataga
    23341 accttgatac tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt
    23401 tctaaatcat ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat
    23461 ggaaggagta taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt
    23521 cttttttcta agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc
    23581 tttgttaccg gtctatacag gggtgttact agatgataag gatggtgctc aggcttctag
    23641 cggcaaattt tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat
    23701 ttcctttata tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc
    23761 ttcttggttc caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga
    23821 gattctacac tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca
    23881 aaatggtaag ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac
    23941 gccttgcgtg gggccggttc tagggtctgt tttggccttg gcggcttcag gtggttcagg
    24001 agcttggcag ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt
    24061 gcttctagct ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct
    24121 cggaatcctc aaaaaagtgg gaggttttct cattattgtg atgggactct tggttctgtt
    24181 tggaaatgct tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga
    24241 aaaaatggca aacatgtgtt cttggagcgg gttcgctcct ttgtttgacg gcttgttcag
    24301 gcaagtccgt gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta
    24361 gtaaaacaag cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg
    24421 gcaagaccta ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt
    24481 cttggtgttc catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg
    24541 gtgatgacta tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag
    24601 cggactttaa gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc
    24661 catcaggcaa acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag
    24721 acaaagaagg caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc
    24781 aaactttgaa ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg
    24841 ttgctaggag tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca
    24901 gggcagacag atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg
    24961 aaaaaaacag aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt
    25021 ttctggggag tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc
    25081 tatgcaaatg gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca
    25141 gaaaccgtcc atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac
    25201 tatttccgca ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag
    25261 taccgtactg gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt
    25321 gatgaggtgg ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat
    25381 tttgtagtgg ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc
    25441 catatcaatg ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca
    25501 agtgatgagg aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat
    25561 caaacagaac gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg
    25621 gatatagcaa ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc
    25681 tggcctagtt ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc
    25741 tacaatatga cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc
    25801 tttacggatg gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc
    25861 cgctttattc ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt
    25921 gattaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg
    25981 tt
//
LOCUS       DBEJJE010000029        25252 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEJJE010000029 DBEJJE010000000
VERSION     DBEJJE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.29"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            179..1660
                     /gene="mgaSpn"
                     /locus_tag="ACL3F5_001248"
                     /gene_synonym="mgrA"
     CDS             179..1660
                     /gene="mgaSpn"
                     /locus_tag="ACL3F5_001248"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0515048.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2022..3023
                     /locus_tag="ACL3F5_001249"
     CDS             2022..3023
                     /locus_tag="ACL3F5_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0515049.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPFSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3173..4090
                     /locus_tag="ACL3F5_001250"
     CDS             3173..4090
                     /locus_tag="ACL3F5_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515050.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4101..4991
                     /locus_tag="ACL3F5_001251"
     CDS             4101..4991
                     /locus_tag="ACL3F5_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0515051.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5020..6636
                     /locus_tag="ACL3F5_001252"
     CDS             5020..6636
                     /locus_tag="ACL3F5_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0515052.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6646..7965
                     /locus_tag="ACL3F5_001253"
     CDS             6646..7965
                     /locus_tag="ACL3F5_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0515053.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            8362..8775
                     /locus_tag="ACL3F5_001254"
     CDS             8362..8775
                     /locus_tag="ACL3F5_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515054.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVPDGYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQEKC"
     gene            9013..9312
                     /locus_tag="ACL3F5_001255"
     CDS             9013..9312
                     /locus_tag="ACL3F5_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515055.1"
                     /translation="MNRNVLEFLKTETAEKISLFIRKINGLEGNVTLLSINSQDLEDI
                     KNAMLSNSNLGLKIARLDVMKKIAYASNRTHYKDGTTIMDDISSGKIHRRPKSYI"
     gene            9366..9587
                     /locus_tag="ACL3F5_001256"
     CDS             9366..9587
                     /locus_tag="ACL3F5_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515056.1"
                     /translation="MLKNFCQNAFISLYFIVSLLGGFSAQVDLKSFSPYQSMKIALLL
                     GVALILLQLPIMFAKLLEALKTKKGETHE"
     gene            9803..11122
                     /locus_tag="ACL3F5_001257"
     CDS             9803..11122
                     /locus_tag="ACL3F5_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGR0515057.1"
                     /translation="MFKIKQTASLSDHYFLNTSKLRSIRWFTIGFLSILSLSSSILFK
                     GWFLQMITLSVGLIITLYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSARFNYQLNDVSIVIQALKSGDEFTREMETLEVLLSSTLGISLSSKEIYATHVEY
                     VFVYRQPERLHVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKFSDIYKLCEFSGFPVENYGTTNEDAFRIVRHYINEMN
                     RRMEIYNKSDLFNSICIDLGFPPLLLIIEEYSSLVASMDAKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGAPTRESSQMVFGTTDVPKVQKGKGV
                     GLYSIEREPPKEFHSPMFDRDVFETIFSIWEFASKDYAKDYMKDEDV"
     gene            11300..11563
                     /locus_tag="ACL3F5_001258"
     CDS             11300..11563
                     /locus_tag="ACL3F5_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515058.1"
                     /translation="MKETVVVLAISTKKDRGWVRVSTANNCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNAQYEVIQSRKLGTFAELIEMAKIK"
     gene            11688..12731
                     /locus_tag="ACL3F5_001259"
     CDS             11688..12731
                     /locus_tag="ACL3F5_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGR0515059.1"
                     /translation="MNKEVLNRAPSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            12747..12929
                     /locus_tag="ACL3F5_001260"
     CDS             12747..12929
                     /locus_tag="ACL3F5_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGR0515060.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKGVVKELLGMEL"
     gene            12931..14058
                     /locus_tag="ACL3F5_001261"
     CDS             12931..14058
                     /locus_tag="ACL3F5_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0515061.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(14141..14213)
                     /locus_tag="ACL3F5_001262"
     tRNA            complement(14141..14213)
                     /locus_tag="ACL3F5_001262"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14178..14180),aa:Lys,seq:ctt)
     gene            complement(14478..15749)
                     /locus_tag="ACL3F5_001263"
     CDS             complement(14478..15749)
                     /locus_tag="ACL3F5_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0515062.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            16019..16219
                     /locus_tag="ACL3F5_001264"
     CDS             16019..16219
                     /locus_tag="ACL3F5_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515063.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            16423..16602
                     /locus_tag="ACL3F5_001265"
     CDS             16423..16602
                     /locus_tag="ACL3F5_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515064.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            16739..16918
                     /locus_tag="ACL3F5_001266"
     CDS             16739..16918
                     /locus_tag="ACL3F5_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR0515065.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            16955..17407
                     /locus_tag="ACL3F5_001267"
     CDS             16955..17407
                     /locus_tag="ACL3F5_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0515066.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            17698..18168
                     /locus_tag="ACL3F5_001268"
     CDS             17698..18168
                     /locus_tag="ACL3F5_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0515067.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            18187..19254
                     /locus_tag="ACL3F5_001269"
     CDS             18187..19254
                     /locus_tag="ACL3F5_001269"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGR0515068.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            19256..19684
                     /locus_tag="ACL3F5_001270"
     CDS             19256..19684
                     /locus_tag="ACL3F5_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0515069.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKDDIPCPNMWELSGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            19822..20772
                     /gene="prmA"
                     /locus_tag="ACL3F5_001271"
     CDS             19822..20772
                     /gene="prmA"
                     /locus_tag="ACL3F5_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0515070.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            20774..21517
                     /locus_tag="ACL3F5_001272"
     CDS             20774..21517
                     /locus_tag="ACL3F5_001272"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0515071.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            21528..23324
                     /gene="pepF"
                     /locus_tag="ACL3F5_001273"
     CDS             21528..23324
                     /gene="pepF"
                     /locus_tag="ACL3F5_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0515072.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            23571..24362
                     /locus_tag="ACL3F5_001274"
     CDS             23571..24362
                     /locus_tag="ACL3F5_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR0515073.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            24473..25141
                     /locus_tag="ACL3F5_001275"
     CDS             24473..25141
                     /locus_tag="ACL3F5_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0515074.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7928 a         4107 c         5357 g         7860 t
ORIGIN      
        1 ctgtattcac gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta
       61 gtgttattat acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc
      121 tttgtggtat aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat
      181 gagagattta ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga
      241 acataaacgt tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc
      301 agtcaaagat gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc
      361 tactaatggt atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca
      421 tttctttaaa cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg
      481 tcaagctgag agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat
      541 tagccaaatc aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt
      601 tcaaatcatt ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa
      661 atattatttc ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt
      721 agaattggtt tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa
      781 gttgctccta gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa
      841 agattctttt aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt
      901 tgctcagagt tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt
      961 atttgtgtct tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt
     1021 aaaaaaggat agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat
     1081 ttcagtcaag tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa
     1141 taccgcacat ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg
     1201 gaatacaatc aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga
     1261 gctttctcac tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct
     1321 atcttatacc ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc
     1381 taaactaaag gttttggtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga
     1441 gacactttct tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt
     1501 atcaaaggaa tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc
     1561 tcctattgaa aataagagac tcatctattc aaataatata aacacggtct cactcatata
     1621 tttgttaaat gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg
     1681 ctatttcgcg tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg
     1741 tttttgttaa gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc
     1801 tctaaaactc ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc
     1861 ctgttttatg tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg
     1921 attttattca tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa
     1981 aagcatttgc atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat
     2041 caattaccat gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg
     2101 taattaataa agaaaaaggc attaaagaag taactttgaa aaaagtggaa caagcgatta
     2161 aaactttgaa ttacattcca gattactacg ctagaggaat gaaaaaaaat cgaacagaaa
     2221 cgattgcaat cattgtacca agtatctggc atcccttctt ttcagaattt gctatgcatg
     2281 tggaaaatga agtctataag agaaataaca aattactctt atgttctatc aatggtacaa
     2341 atagagagca agactatctg gagatgttgc gtcataataa agttgatgga gtggttgcca
     2401 ttacctatag tccaattgaa cattacttga cgtcaggaat tccctttgtt agtattgacc
     2461 gcacatactc agatattgcc attccttgtg tttcatcaga taatgatgca ggtggaagag
     2521 aagcagctaa acaattaatt agtaaaggat gtcagcattt agcctttgtg ggcggacata
     2581 atacaaccat taatgaaacc aaacgtcgta gaatttcatt tgaaaagtat gtccaagagc
     2641 ataaaatacc ttttagtatt tttgatttgg atgagacagt tactgactat tatggaaagc
     2701 tagagagttt cttggaagaa aattcttcta tagatggaat ttttacaatc aacgatttta
     2761 cagctttgga tgtgattgaa atactaaaaa aaaatggcaa acgtattcct catgatgtcc
     2821 aaattattgg atacgatgga attaaaatgg ctggagatag agattatcta ctttcaacta
     2881 ttgaacaacc attggaagaa atggcaaaag aagcggttcg tattttgttt gatataattg
     2941 atggaaagac tgttaatttg cagacaatcc taccagtaaa atttgttgaa ggaaaaacaa
     3001 caaaaaatga aaataagtct tgacagaaag cgctatcaat gatagaatga attcagataa
     3061 aaagatttat ttttaaaaca aaaatgaaac gtttcaaaaa aagaaataaa gagacagcgt
     3121 caagcgctat cttttctaga aaaaaatgaa acgtttcaaa aaggaggttg ctatgaatag
     3181 caaagcgaag caagtttctc tttgggaaag aatcaagaaa caaaaactct tgttattgat
     3241 gactgtcccc ggtttagttt taacctttat ctttaaatac atccctatgt atggggtctt
     3301 aatcgcattt aaagattaca atcctttaaa aggaatttta gggagtgatt ggattggttt
     3361 ttctgagttt acaaaattca tatcctctcc caactttggt atcttgttag ccaacacatt
     3421 aaaattaagt atctatggtt tattgcttgg ctttttacca ccaatcattc ttgctattat
     3481 gctcaatcaa ctcttgagtg aaaaagtcaa aaaacgaatt cagctcattt tatacgcacc
     3541 aaactttatc tcagtcgttg ttattgtcgg tatgattttc ctcttctttt cagtgggagg
     3601 accaatcaac aattttcttt ctatgtttgg aatgaaggct gacttcttga caaatccaga
     3661 cttctttaga cccttataca tctttagtgg tatctggcaa ggaatgggct gggcttcaac
     3721 gctctacacg gcaacattgg taaatgtaga tccagcctta gtagaagcag cccgactgga
     3781 tggagccaat atcttccaac gaatctggca cattgatatt ccagctctta agcctattat
     3841 ggttatccaa tttgttttag ctgcaggtgg aattatgaat gtcggatatg aaaaagcatt
     3901 cttgatgcag acatcgttaa atttgccaac ttctgaaatt atctcgacat atgtctataa
     3961 agttggtctt gtatcaggag actattctta ctcaacagcg gttggtttgt ttaatgcagt
     4021 gatcaacgta gtattgcttg ttgcagttaa ccaaatcgtt aaacgcatga ataatggtga
     4081 aggaatttaa ggaggaaagt atgaaaaatt cgattatgga tacaaaattt gatagacgta
     4141 tcttactctt aaataaaatc attattgtct ttatcgtttt gatgactttg cttcctttac
     4201 tttatatcgt cgtagcatcc tttatggatc ctaaggttct ggttagtaga gggattagct
     4261 ttaatccagc cgattggact gtagaaggtt accagcgtgt attcagtgac caatctattc
     4321 taagaggttt tatcaattct ctactatact cttttggatt tgcagcttta acagtattgc
     4381 tatctgtgtt tacagcttat cctctttcta agaaagactt ggttggacgt cgttggatta
     4441 actacttctt gattgtgact atgttctttg gtggtggttt agtcccaact tacttgctcg
     4501 taaaagaatt gggaatgctc aatactccat gggctatcat tgttccaggt gctgtcaacg
     4561 tttggaatat tattcttgct agggcctatt tccaaggatt gcctgaagaa ttagttgaag
     4621 ctgctgtcat tgatggtgca aatgatttac agattttctt caaaatcatg cttcctcttg
     4681 caaaaccaat tatgtttgtt ctcttccttt atgcttttgt aggacagtgg aactcatact
     4741 ttgatgcaat gatttatatc aaggatccaa acttggaacc attgcaactt gtacttcgta
     4801 aaattctcat tcagagccaa ccaggtcaag acatgattgg agcacaagcg gctatgaatg
     4861 aaatgaaacg tttagctgaa ttgattaaat acgcaactat tgtcatttcc agcttgccat
     4921 tgattgttat gtatccattc ttccaaaaat actttgataa aggaattatg gctggttcac
     4981 ttaaaggata aaaaaagaaa aaataaaagg agttttctca tgaaattcaa aacattctca
     5041 aaatcagcag ttttgttgac agctagttta gcagtacttg cagcctgtgg ctcaaaaaat
     5101 acagcttcaa gtccagatta taagttggaa ggtgtaacat tcccgcttca agaaaagaaa
     5161 acattgaagt ttatgacagc cagttcaccg ttatctccta aagacccaaa tgaaaagtta
     5221 attttgcaac gtttggagaa ggaaactggc gttcatattg actggaccaa ctaccaatcc
     5281 gactttgcag aaaaacgtaa cttggatatt tctagtggtg atttaccaga tgctatccac
     5341 aacgacggag cttcagatgt ggacttgatg aactgggcta aaaaaggtgt tattattcca
     5401 gttgaaaatt tgattgataa atacatgcca aatcttaaga aaattttgga tgagaaacca
     5461 gagtacaagg ccttgatgac agcacctgat gggcacattt actcattccc atggattgaa
     5521 gagcttggag atggtaaaga gtctattcac agcgtcaacg atatggcttg gattaacaaa
     5581 gattggctta agaaacttgg tcttgaaatg ccaaaaacta ctgatgattt gattaaagtc
     5641 ctagaagctt tcaaaaacgg ggatccaaat ggaaatggag aggctgatga aattccattt
     5701 tcatttatta gtggtaacgg aaacgaagat tttaaattcc tatttgctgc atttggtata
     5761 ggggataacg atgatcattt agtagtagga aatgatggca aagttgattt cacagcagat
     5821 aacgataact ataaagaagg tgtcaaattt atccgtcaat tgcaagaaaa aggcttgatt
     5881 gataaagaag ctttcgaaca tgattggaat agttacattg ctaaaggtca tgatcagaaa
     5941 tttggtgttt actttacatg ggataagaat aatgttactg gaagtaacga aagttatgat
     6001 gttttaccag tacttgctgg accaagtggt caaaaacacg tagctcgtac aaacggtatg
     6061 ggatttgcac gtgacaagat ggttattacc agtgtaaaca aaaacctaga attgacagct
     6121 aaatggattg atgcacaata cgctccactc caatctgtgc aaaataactg gggaacttac
     6181 ggagatgaca aacaacaaaa catttttgaa ttggatcaag cgtcaaatag tctaaaacac
     6241 ttaccactaa acggaactgc accagcagaa cttcgtcaaa agactgaagt aggaggacca
     6301 ctagctattc tagattcata ctatggtaaa gtaacaacca tgcctgatga tgccaaatgg
     6361 cgtttggatc ttatcaaaga atattatgtt ccttacatga gcaatgacaa taactatcca
     6421 agagtcttta tgacacagga agatttggac aagattgccc atatcgaagc agatatgaat
     6481 gactatatct accgtaaacg tgctgaatgg attgtaaatg gcaatattga tactgagtgg
     6541 gatgattaca agaaagaact tgaaaaatac ggactttctg attacctcgc tattaaacaa
     6601 aaatactacg atcaatacca agcaaacaaa aactagaggt tgattatggg agataagaaa
     6661 tacacagtag aaaaagccaa tcgttttata gcagaaaata aacatctcgt taatactcaa
     6721 tataagcctg aagaacattt ttcagctgag attggttgga tcaatgatcc aaatggattt
     6781 gtctattttc gtggagaata ccatctcttt tatcaattct atccatatga tagtgtttgg
     6841 gggcctatgc actggggaca tgctaaaagt aaggacttgg tgacttggga gcacttgcca
     6901 gtggcacttg ctcctgacca agattatgac cgaaatggtt gtttctcagg ctctgccatt
     6961 gtcaaggatg atcgcctctg gctcatgtac actggacata tcgaagaaga aaccggtgtc
     7021 cgccaagtgc aaaatatggc attttcagat gacgggattc actttgaaaa gattgaacaa
     7081 aatccagttg caactggatc agacttgcca gatgagttga ttgctgctga ttttcgtgat
     7141 ccaaaactct ttgaaaaaga tggacgctat tactccgtag tagctgccaa acacaagaat
     7201 aatgtgggct gtatcgttct actagggtcc gataacctag tagaatggca gttcgaatcc
     7261 atctttttaa aaggggtaga acaccaaggc tttatgtggg aatgcccaga ttacttcgag
     7321 ttagatggga aagattgcct tattatgtca cccatgcgtt atcagcgtga gggagactca
     7381 tatcataaca tcaactcatc gcttttgttc acgggtaagg tagattgggg agaaaaatgt
     7441 tttatcccag aatcagttca agaaattgat catggccaag acttctatgc gcctcaaaca
     7501 ttgttggacg atcaaaatcg tcgtatcctg attgcttgga tgcagacatg ggggcgtacc
     7561 cttccaaccc atgaccaaga acacaaatgg gcatgtgcca tgactttacc tagaatttta
     7621 agattggaag atggcaaact aagacaattc cctgttaaaa aaggccaata tcaaatccaa
     7681 atagataaag attgtcatta ccacttagga aatgatatag attatcttga atttggttat
     7741 gatagtaatg cgcagcaagt ttacattgat cgtagccatc ttattcaaaa aattctaggt
     7801 gaagaagaac aggacactag tcgacggtat gtagatattg aagctaaaga attggaagtt
     7861 gttctagata aaaattccat cgagattttt gtcaatcaag gtgaagcaag cttgactgca
     7921 acttattact taacggtgcc agctgagcta tcacgaattg attaaaaatt aagttatttc
     7981 tcctaaagaa aaagttctct ttctaaaata gtggaaagag gactttttgt gttttgggta
     8041 tataagctta gtttatggta tttgtaaaat tggtgttgga ttatgattta agctagtttt
     8101 ctaaagaatt tgaaaaaaat tttatttaag caaaaaaaac ccttggttcc aaggcttttc
     8161 ctgttgtatt tatatgcccc ctacaggaat tgtaggagat atgttgttta gatgttcttg
     8221 attttctggt gttttgtaac gtttaaatga gttttttgag tttgttggtg gggcgttgcc
     8281 cggcaattgc ccgacttatt gtttgaaaaa gaatttaaaa tatggtatag ttaattatag
     8341 attaacactt ggggggaata gatgaagaat aatgaaagat taggtattaa attaagtaga
     8401 gatagcgttt taggattgag ggaagttaga aggctttatt taggcagttc agatatccca
     8461 gtgcctgatg ggtatgtgat tgaagttgct tataaacaga tatcaaatga gattgatatt
     8521 attgattggg tagagttgaa caagtcaaaa attaagataa gtgaaattag tgaaagcgta
     8581 gatatagatg ccactagctt gagaacaact ttgactttag acacgttagt atatgaaggt
     8641 atgagagata tacagttaaa gttgagagag cttacaaagg ggagagtatt cttttcattt
     8701 gtagtgaagt tagttttatt tgcttctatt ttaaagaaaa aaggtttact agaaaaattt
     8761 caagaaaagt gttaatcaag tattgacttt ttagttgagt tcaagtatac tttaattaga
     8821 gagatttctc tctaaatttt ttcgcttctt ttgtgttaat caatgacaaa ctctttgtct
     8881 tattttttaa cgcttgggtg tgttaatcaa agatgtatat attggaggat gaagatgaaa
     8941 gctagagctt caccgttgaa ttgattttgt ttctagaaaa aatcaataat tagaaaaaat
     9001 aagaggtaag aaatgaatag aaatgtacta gagtttctga aaacagagac agctgagaaa
     9061 attagccttt tcatcaggaa aataaatgga ttagaaggaa atgtgacatt actttctatt
     9121 aactctcaag atttggaaga tattaaaaat gctatgcttt ccaattctaa tctcggatta
     9181 aaaattgcga gactggatgt gatgaagaaa atagcatatg cttctaatcg tactcattat
     9241 aaagatggaa cgactatcat ggatgacatc tcatctggta aaatacatcg tcgccctaaa
     9301 agctatatct aataaggaag gttaatccct cttccttatt agatatttaa aaaaaggaga
     9361 aaaatatgct taagaatttt tgtcaaaatg cctttattag tttatatttc atagtgtctc
     9421 tgctaggagg attttcagct caggttgacc taaaatcctt ctctccttat caatctatga
     9481 agatagcctt gttattagga gttgctttaa ttttattgca acttccaata atgtttgcta
     9541 aattattaga agctttaaaa accaagaaag gtgaaactca tgaatgacat cgtaaaaatg
     9601 agattagcct tttgtatcac tataatattg atggcatgct ctgtttttgt gtttactcct
     9661 gttggagaag gcatgtccct actttgctca atttttgcta ccccgttttt atttattttt
     9721 gttttctatt tttttaaaat aaaattaaga attttactta ttattatcaa ggatttcata
     9781 aaaaaattta gataggtata agatgtttaa aattaaacaa acggcttctt tgtctgatca
     9841 ttatttttta aatacatcta aattgagaag tattcgctgg tttactatag gatttttgag
     9901 catattgtcc ctttctagta gtattctttt taagggatgg tttcttcaaa tgattacatt
     9961 atccgttgga ttgattataa ctttgtatat tgaaagaaaa atcaagggat gggctcagca
    10021 gattgaaccg ctgttaattg tcagagaaaa ccttctattt atgcttcgca gaaattcctt
    10081 tctttttaca gcaacaaaag atggcgctat tcttcgttca gctagattta attaccaatt
    10141 gaatgatgtt tccattgtaa ttcaagcatt gaaatctgga gatgaattta cgagagagat
    10201 ggagacttta gaggttctcc tatctagtac tttgggaata agcctatcgt caaaagaaat
    10261 ttatgcgact catgttgaat atgtttttgt atatagacag cctgaacgtt tacatgttac
    10321 ctccctccct cttgaagatg atagcctgaa aattaaaatc tatgatgatt ttgttatcga
    10381 tttgagaaaa aacttttcca tgcttatatc gggggcctcc ggtagtggta aatctttctt
    10441 tacatattat tacttgactc gtttcatatc tcagaccgta aatgggaaac atgcaaaaat
    10501 atatgtgatt gacccaaaat tttcagatat ttataaatta tgcgaatttt ctggttttcc
    10561 agtagaaaat tatggaacaa ctaatgaaga tgcctttaga atcgtgcgtc actatattaa
    10621 cgagatgaat aggcggatgg aaatttacaa caaaagtgat ctgttcaata gtatttgtat
    10681 agacttgggc tttcctcctt tactgttaat aatagaggag tattcatcgt tagtagcttc
    10741 gatggatgct aaagctaaaa aagattttga aaatatggtt gctatcgttg ctcaaaaagc
    10801 aaggtctcta tctatggggg tttgtattgt tatgcaacaa ccccgttccg atagcctttc
    10861 taccaatatt agagaacagc ttgtcaatgc tatatttctt ggagccccaa ctcgcgaatc
    10921 tagccagatg gtgtttggca caacagatgt gccgaaagtt caaaaaggca aaggggtggg
    10981 actttactct atagagcgag agcctcctaa ggaattccat tccccgatgt ttgatagaga
    11041 tgtgtttgag acaatttttt caatttggga atttgcttct aaagattatg ctaaagatta
    11101 tatgaaggat gaagatgtat gagaatttta agcgttttga agatgaataa aattctttta
    11161 ttcattttca aaatgccatt gtgcagccgg cgaacaacaa ggccggtcgg acgtaacgtc
    11221 cgaataaatg tatttatgtc caatactgat tgacgttaaa agctgtatat tactttaaat
    11281 aaggaaggat tttttaacta tgaaagaaac tgttgttgtt ctggccattt ctacgaagaa
    11341 agacagaggc tgggtaagag tttccacagc caataattgt tggagtgacc taggtatgca
    11401 tttcgataaa tccaaatttg gagctgtttt ctctgctcca ggcctttatg aggttgaagt
    11461 gattaataat gcttcatttg gacagaatgc ccaatatgag gtgattcagt ccagaaagct
    11521 tgggaccttt gcagaattga ttgaaatggc aaaaattaaa taatttatat ttagggtaag
    11581 gctggacctg ccagctttgc tggcaagtgg agcgtggtca gtggaacggc agtcttaccc
    11641 taaaatttaa gtatatagaa tgttttgttt tttgaaggag aaatttcatg aataaagaag
    11701 ttttaaatcg ggctccttct aatagcccga taacgataca tcaaatgtct aataagagtt
    11761 actctaaatt tcaagaggaa gtatctctga agtatgggtt tatcggtctg aaattggata
    11821 agctaagttt gaccgctgaa gttagtgagg aatttcattc tgagattctt agtgggaact
    11881 tcaccttata tgattatttc ggtgtagttg agccgaattt aaatagaaat ggtgaactag
    11941 ctagttataa agggcaattc tttaatgatg aaaaagagaa ttggtatatc gagtataccc
    12001 ccgttgcgtc gattaagatg aacaaaagac ctttaaagat tgaatttact ccttcaaaag
    12061 tttcaaaaaa gaatttttta attgtctttc atagaatgtt tccgtacatg tttaacatcg
    12121 caatctctac ttttcattta gcctatgatt ttgagcgaga tttatctgct ttacgtgtaa
    12181 attggccaaa agtaatgtat cgtcctattt ataaggggat gaaacttgag actatggatt
    12241 ttggtgctcc taaaggtaat tatcatctaa ctgcttataa taaacttaaa gaacgtatgg
    12301 atagtggaga tatggcagaa atagaaattt atcagcaata tgataatcta tggaggattg
    12361 agtataaatt ctacaatgaa ggcaacataa aaaaagaatt aaaaaatgga ttaccattct
    12421 tagctaaaat tccagtgtat attgaaaatt tcaaaggctt agaatttaat aatttaggag
    12481 ttaatgagaa gatttatctt ttcgctcttc gtaataaacc tgaattattt gcagaatctg
    12541 ataaacgaac ggtagctaag tataaaaaac ttgccgaaag tatctctgaa gttaatttga
    12601 atgtcttttt tcaaaatgct ttagattttg ttgaaatctt taatcaagag ccttgtctga
    12661 taaatttttt tgagtttatg aattctatgt tacaaggcga tattccaaag ttaacaataa
    12721 accaagaata ataagagggg aacagtatga aagatacgat ttctaataag gatttgattt
    12781 ccatgggcta tagaccatca acagcaaatg ctattatcca tcaggcgaga gaattacttg
    12841 tatcacgagg ctatacattt tataatcgca aacgtttgat ggttgttcca aaaggtgttg
    12901 tgaaagagtt gttgggaatg gaattgtgaa atggcttata tcgagtataa acagcgtggg
    12961 aagaaaaggc tttggtcctt ttctataaga gaaagaagca agagcctact ccataaaagc
    13021 ggatttaaaa caaaacgaga agctaaaata gaagcggaga aagttcttca taagttaaat
    13081 actgggagtg tcttaagctc tagtatgact ttatcggagc tttataatga atggcttgat
    13141 ttaaaaattt tacctagcaa tagaagtgta gttactaaaa aaaaatatct catgagaaag
    13201 aaggtcatcg aaaggttatt tggaaataag cctgtatcac aaattaagcc tagcgagtat
    13261 caaaaaatta tgaatgagta tggagagact gtatcgagaa atttcttagg aagattgaat
    13321 tcttgtattc gggcaagtat acagatggct attgctgata aggtgataat agaggatttt
    13381 actgcttatg ttgagttgtt ctcttctaag agtggacaaa aggttgagga aaagtatttg
    13441 catgctgagt cagattatca aaaagtttta gtatatttga aaaataagtt tgattatcaa
    13501 aaatctattg taccgtatgt aatttatttc ctttttaaaa ctggcatgcg tttctccgaa
    13561 ttgattgctc taacttggga tgaagttgac gagcttaatg agcaacttaa aacttatcgt
    13621 cgttacaaca ctgctattca taagtttact ccacctaaaa acaatacttc aataagatta
    13681 gttcctatta cttcagatat gctttccttg ttaaaaacat tgaaaatatt gcaattaaaa
    13741 acaaataaag aattaaatat tgataatgaa aataatttga tttttcagca ttttggctat
    13801 gtctacgatg ttccagatat tgcaacagtc aataaagcta taaaagtaat gttgaaggaa
    13861 ttgcaaattt ttccattgat tactaccaaa ggagctagac acacttatgg tagttattta
    13921 tggcataata atattgattt gggagttata gcgaaaattt taggacataa agatatctcc
    13981 atgttgattg atgtttatgg gcataccttg gaggaaaaaa ttagtgagga gtttatggct
    14041 gtgaaaagtt tgttgtaaaa acacggcaaa ttgcacgaca atttttaaaa ggaaagcaaa
    14101 aaaagcccta tattataagg cttttcctgt tgtatttaga tgccccctac agggatcgaa
    14161 cctgtgaccc acggattaag agtccgctgc tctgccagct gagctaagga ggcaaagaaa
    14221 aaagctgtat tggtgccgaa acttcacggt ttgtattgaa cccgcgcaat taagcaggtg
    14281 ggcaactcgc tctaactgaa gctgtttccg tgtgagacgg cctacatgct gttagaagac
    14341 ttttgtttcc ctaataatac aaaaaatagt cggtcaacac ttaagtgtga agtcgtacac
    14401 cacagcgttt ctatacttat atgataccac tttttcaaaa aaaatcaaga ggaaagtgca
    14461 attttttgaa aaggatttca gatttttcgc aaacggtcga tagcttcctt tctttgagcc
    14521 aaagcccgtt catatttacc agtatcttct gcttggaaat agtgatgatt acgaattttt
    14581 tctggcagat agtcttgctt gacccaattt ccaggatagt tgtgtggata gagatagtct
    14641 tgggcattcc ccagttcctt gcttccactg tagtgcccat cacgtaggtg tcgcggaata
    14701 ggcaagtgcc ctgatgtttt gaggtcagca agtgccttat ccatagctac ataggctgag
    14761 ttggattttg gagaaagggc caaatcaatc acgacattgg caatgagaat gcgggcttct
    14821 gggaacccaa tcttctgggc agcatccaga gcagtcacgg tatgaatctg ggcctcagga
    14881 ttggctaagc cgatatcttc ataggcgata acagtcaagc gacgagcgag actaggcaga
    14941 tccccagcct caatcaagcg ggcagtatag tggagactgg catccacatc tgagccacga
    15001 atagactttt gcagggcaga tagaacatca tagtgaccgt ctccatcctt gtccatagtg
    15061 atgtagcttc tctgaagact attttccatg atgtctaagg tgatgtggcg aatgccctcg
    15121 tcattctcag gggtagagag aacagctaag tccagtgagt taaaggcaga gcgaaggtct
    15181 ccgtttgtag aggttgcgat gaaatccagc gcatcctcat ctagttctat tggaaaatca
    15241 aaaccacgtt cagggttact tagagctatc tgcagggcct ctttgacgtc ttggttagac
    15301 agaggttcca actcgaaaat ttgaactcgg ctacgaatgg caggagtgac agagaagaaa
    15361 ggattttcag tcgttgctcc aatcatgatg accagtccac tttccaagag aggcaagagg
    15421 aagtcttgct tggtcttatc tagtcgatga atttcgtcta gcaataggac gagaccacca
    15481 gaaaatttag cttcttccga gatttcttgc agtcgctttt tactatcaac tgtcgcattg
    15541 aaagttcgaa aggcatactt ggtcgttcca gcgatggcag aggcaatact ggttttgccg
    15601 attccaggag ggccatatag aatcatggag gacaggcggt tggcttccac catgcggcgg
    15661 atgatttttc caggtccgac cagatgctcc tgaccgatga cctggtcgat ggttttaggg
    15721 cgcatgcgaa gcgcgagatt gtctggcata gcagtccttt ctagcgtgga tttgagtaga
    15781 atgactcatc tactatatct tactatgtcc attctagcct attagttgtg atatttcaat
    15841 ggttttgtaa taatcaggga gtgagataga atctttttta ctatttaatt taatgaggag
    15901 aggtatcagc atgagagatt tgattttcct taaagctcaa aataggatag ttgagcctaa
    15961 agaagtggaa gtgctgactt gagaaataat attgctgaat gtcattgtat gaactataat
    16021 gaaaagagag gtgataagca atggaaatga tggaccaagt caggaaattt tgatttttac
    16081 aaaacaaatt cgtcattgga ttcttagtga tcaagttatt tcagggaaaa gaaaactttt
    16141 cttccgggaa gatactccaa aagagatttt agatttgtac gaaaacatta aatctaaact
    16201 tgattttgct taccaataag tttattctaa taatgggttg aaaaaatatg aaaaatagaa
    16261 taattgatgt ttttgaagta gtaaatcgca tccttgtaat aactgttgaa aatcctgatt
    16321 tcgaagactt gagagttaat catactcaat gaaaatcaaa gagcaaacta ggaaactagc
    16381 cgcaggctgt acttgagtac ggtaaggcga cgttgacgtg gtttgaattt gattttcgaa
    16441 gagtatcagt ttgtaaaaat tggagataaa aaatatagag tacgcagtgt tcctatgatt
    16501 cattcaactc cgcctcaatc tgtcttagat cgagatactt ttacaattga ctatacagat
    16561 gatgaattgc tcgataaaga agcagttttt actactcatt agaaaaatag gtctgaataa
    16621 attggcttcc cttagaacca catctagggg cttttatgta taatagaata ataagtatca
    16681 ctcctttaca atacgtgtaa cacgtgttat aatggtgttg tcaggaggta aaagcgctat
    16741 gcctatgaca caaaaagaga tggttaaact ccttacggcc catggttgga taaagactag
    16801 aggcggtaaa ggctcccata ttaaaatgga gaagcaaggg gaaagactta tcacaatccc
    16861 tcatggtgag ctgaataagt acactgaaag agggataaga aagcaagctg ggttgtaaaa
    16921 ttcagcccct gttttttgat atggaggtag tgaaatgtta gttacgtatc cagctttatt
    16981 ttattatgac gacacagacg gaacagaagc gacttatttt gtccatttcc cagattttga
    17041 atactcagct acacaaggag aggggatttc tgaggctttg gctatggggt cggagtggct
    17101 agggataact gttgcagatt tgatagagag tgatggagag ttacctcagc catcagatat
    17161 caatagcttg tctttaattg ataatgatcc ttttaaagat gatgaagatt tcgtgtcaac
    17221 ctatgacctt gataaatctt ttatttctat ggtatctgtt gatgtatcag aatacctagg
    17281 aagtcaggaa cccataaaaa agactttgac cataccaaaa tgggcagata agttgggacg
    17341 agaaatggga cttaactttt ctcagacttt gacagacgct attgcagata agaaagttca
    17401 agcctaagat taagcgtggt atcgtggtaa tagtcaataa aaaagcacgt ccacttgtgc
    17461 tagttactcg cctattgatt ttatagattt attagccctt tcgcgggctt tttatattga
    17521 tttttatgag aaatgaagaa atcagacttt taagaaaatc actgatacca agggtttaaa
    17581 tgaggtaata tggtataatt aggacataaa ataattttgt ggtaagatgg tagtatctat
    17641 tttagcatat ttccgagcaa tcggggcgat taaagagtcg catagaaaga ggacaaaatg
    17701 gcaacatacg gatttttaga tgttttagag gaagagttgg acaagaactt tccctttgac
    17761 tttgagatta gctgggacaa acgcaaccat gcggtagaag tgagttttct attggaagcg
    17821 caaaatgctg caggtgtgga gatggtggat gaagacggag aggttttatc agatgacatt
    17881 ctttttgagg aagcggtcct tttctacaat cctgccaagt caacagtcaa tgaggaagac
    17941 tatttgactg ttattcctta cctgcctaaa aaaggatttt cccgtgaatt tttagcttat
    18001 tttgcgcttt tccttaaaga tactgctgag gttgggctag atgtcctcat ggactttttg
    18061 gaagacccag aagcagagga atttgtcatg gaatggaacc aagaagtctt tgaagaagga
    18121 aaagttggct tggaagaggg agaattttat ccttatccaa gatactagga gttggttgga
    18181 ggtgttatga agaaaattgg gacttatttg gtttatgtgc tagcttttgt ctttattatg
    18241 ctagcttttg cttgtggaac aatcgcattt gcagagttgg ggtattccgc agttttagcc
    18301 tttacttttg gttatgcctt cgctcttcta agcatgtatt taatctttat tcttcatgag
    18361 ctgggtcatg ctttttgtgg ctacttgaca ggctatcggc tggtggcttt tggattagga
    18421 cattttattt tgaccaaaaa gtcaggcagg tttcatctta gtagaacagc cattctgaaa
    18481 aatgttggtg ctcaatacat tggtttaaaa gaggatgaaa gcgatcaaag aatcatcctg
    18541 atgctttcag gaggcttgat ggttcatctc ggcttgatat tattggcgat agtgtttgga
    18601 tttttgacaa gaagctggta ttttgcaggg acttggattt ttcttaattt atctttcttc
    18661 ctaaataaca ttttaccagt cggcatcacc gatggagcaa aaatttggga attactacaa
    18721 caccctgaaa ataccaaata cgcctacctg gtattgagac attctgctca aactttgctg
    18781 gctcctcaag aatatgattt gaaagacttt gttcaagcag ttcctgagga tgcacgaggg
    18841 agttttgcgg atggtgtatt aggtatgcaa ggtgaagttt ccattttgga agggaaggaa
    18901 gaagtagcta aacagcagtt tcaagcatta cttgagagga caactactcc gatgatgcag
    18961 acagttgccc aactatccct acttcatatc gccttgttgg aaggagattt tgagcaagcg
    19021 gagcaatatg ctagtattcg acaggtcaaa tcgtttctgt ctctcaaact gtccaatctt
    19081 caagtgatac aagcctggta tcaattaaag gtgaagaaag atgtagatcg aactcgtaag
    19141 gctctcaaga ttgctagaca gaaaatggat agtagtcgaa tgttgaggga cgagaaacgc
    19201 tattatgaaa acttgttagc agagctggaa aaggaattag ccgaaggagt ctaatatgga
    19261 aatagagatt tctgatttca caggttgcaa gattgctttg ttttgtgggg ataagctact
    19321 gacgattttg cgtgatgaca aggacgatat cccttgtccc aacatgtggg agttgtcagg
    19381 tggtggccgt gaaggggacg aaagcccttt tgaatgcgct cggcgtgaag tttatgagga
    19441 actgggaatt catttagatg aagactgtct gctttggagc aagatttatc ctagtgtaat
    19501 ttttaaaggc aagaaatcgg tctttatggt tggtcagcta agacaagaac aatttgacaa
    19561 tatcatcttc ggagatgaag gacagggcta tcagctgatg aatgttgagg aatttcttag
    19621 ttccagtcaa gttgtgcctc agttgcaaga gagattaaaa gattatttaa aagtaagtga
    19681 ttagaaagga tggttcagtt aaatttctaa actgaacccg ccctaaacac tgtgccaaaa
    19741 agataaactt ctcttagaca caagcgtctt cagagaattt cctattttgg ttttgtgttt
    19801 tacgggcttg gtatcttaat gatggaaaca tggcaagagt taaaagttac agtgaagcgt
    19861 gagggagagg agttggtttc caatctcttg attgagctgg gagcgcaagg tgttgcgatt
    19921 gaagacagta tggactatgt gggaaatgtt gaccgcttcg gcgagatttt cccagaggtc
    19981 gagcagcaag aagaaatcgt agtgacagcc tactaccctg acacggtgga tgtgacagtg
    20041 gttgaggcgg acttgcaggc tcgcatatca gaattgacgg attttatgga tttgggagag
    20101 ttaaaaatag gtacgactgc cttggctgag gaagactggg cagataactg gaagaaatac
    20161 tatgagccag ctcgtatcac tcatgatttg accatcgttc cctcttggac agactatgag
    20221 gcgactgcgg gagaaaaaat tatcaagctg gatcctggca tggcttttgg tacgggaacc
    20281 cacccaacta ccaagatgag catttttgcc ttggaacagg ttcttcgtgg tggcgaaacg
    20341 gtgctagatg tgggaactgg ttcaggggtt ctctctattg ccagctcgct tctgggggct
    20401 aaagaaattt tcgcctatga cctggatgat gtggcagttc gtgtggctca ggaaaatatt
    20461 gagctcaacc ctggaatgga aaatatccat gtagcggcag gcgatttgct taaaggcgtg
    20521 gagattgaag cagatgtcat cgtggcaaac atcttggcgg atatcctcat tcatctgaca
    20581 gaggatgctt atcgcttggt taaggatgaa ggttacctga tcatgagtgg cattatcaag
    20641 gataagtggg acatggtgcg cgagttggct gaatcagctg gatttttcct cgaaactcac
    20701 atggttcaag gggaatggaa tgcctgtgtc tttaagaaaa ccaaggatat ctctggtgtg
    20761 attggaggct agcatgcagc agtattttgt aaaaggcagt gctatctctc ctgtcactat
    20821 cgagaacaag gaaaccagta agcatatgtt tcaggttatg cgcttgaaag aagaggatga
    20881 ggttacctta gtctttgatg atggcatcaa gcgcttggcg cgcgtgctgg atatggaaaa
    20941 tcgtcagttt gagttggtcc aagaattaaa tgacaatgtg gaactaccag ttcaagtgac
    21001 catcgcatct ggatttccca agggagacaa gctggagttc atcgctcaaa aagtaaccga
    21061 actgggtgct agccaaatct gggcctttcc tgcagactgg tcagttgcca agtgggatgg
    21121 caagaaattg ggtaaaaaag ttgaaaaact agaaaaaatt gcccttggag cagccgagca
    21181 aagcaagcgt aatattgtac caagtattaa acttttcgag aaaaaagcag attttctaac
    21241 tcagctggac cagtttgact ctatcatagt agcctatgaa gaatcaggta aagaaggaga
    21301 agccgctgcg cttctgcaag cagtcactgg tcttgaaaca ggagccaaac tgctctttat
    21361 ctttggtcca gaaggcggtc tctcacctgc agaaatcgaa agttttgaag ctaagggagc
    21421 cgttttggta ggcctaggtc ctcgtatttt gcgagcagaa acagcaccgc tttacgcctt
    21481 atcagccctt agtgttttag tagaattaga gaaataagag gaagaaaatg gaacaaaaac
    21541 accgttcaga atttccagag aaggaactct gggacttaac agccctatac caagaccgtg
    21601 aggatttctt gcgtgcaatc gagaaagctc gtgaagacat caaccaattt agccgtgact
    21661 acaagggtaa tcttcatact tttgaggatt tcgagaaggc ctttgcggaa ttggaacaga
    21721 tctacattca gatgagccat attggcaact atgcttttat gcctcagacg acggactata
    21781 gcaatgacga atttgccaat attgcccaag ctgggatgga atttgaaaca gatgccagcg
    21841 tagccttgac cttctttgac gatgccttgg tggtagcaga cgaggaagtc ttggaccgtt
    21901 tgggtgaatt gcctcacttg acggcagcta ttcgtcaggc caaaatcaaa aaagcccact
    21961 atctaggggc tgatgtggag aaggccttga ccaatctcgg tgaagttttc tatagtccgc
    22021 aggacattta tactaagatg cgagctgggg attttgaaat ggctgacttt gaagcccatg
    22081 gcaagaccta taaaaacagc tttgtcacct atgagaattt ctaccaaaat cacgaggatg
    22141 ctgaggttcg tgagaaatcc ttccgttcct tctcagaggg acttcgtaag caccaaaata
    22201 cggctgcagc agcctatctg gctcaggtca agtctgaaaa actcttggct gatatgaagg
    22261 gatacgactc tgtctttgac tatcttctag ctgaacaaga agtggaccgt gtcatgtttg
    22321 accgccagat tgacctcatc atgaaggact ttgcaccagt cgctcagaga tacctcaagc
    22381 atgttgccaa ggtaaatggt cttgaaaaga tgacctttgc agactggaaa ttggacttgg
    22441 acagcgccct gaatcctgaa gtgactattg acgatgccta tgatttggtc atgaagtcgg
    22501 tagaaccttt ggggcaagaa tattgtcagg aagttgctcg ttaccaagaa gagcgctggg
    22561 tggactttgc tgctaacagt ggcaaggatt ccggtggtta tgcggcggac ccatatcgcg
    22621 tacaccctta tgtcctcatg agctggacag gccgtttgag cgatgtctat accttgattc
    22681 atgaaatcgg gcattctggt caattcatct tttcagacaa tcatcaaagt tacttcaatg
    22741 cccatatgtc gacctactat gttgaagcac cgtcaacctt caatgaattg ctactcagtg
    22801 attacttaga gaaccaatct aatgacccac gtcaaaaacg ctttgctctg gctcatcgct
    22861 tgacagacac ctacttccat aactttatca cccacctctt ggaagccgcc ttccagcgta
    22921 aggtgtatac attgattgaa gaaggagaaa ccttcggagc aagcaaactc aacagtatta
    22981 tgaaggaagt tttgacagat ttttggggcg atgccattga aatcgacgac gatgcagctt
    23041 tgacttggat gcgccaagct cactactata tgggcttgta tagttacact tactctgctg
    23101 gtcttgtcat ctcgacagct ggttaccttc atcttaaaaa ctcagaaact ggagctgaag
    23161 actggctcaa tctcctcaaa tcaggtggta gcaagacacc acttgagtca gccatgatta
    23221 tcggtgctga tatttcaaca gacaaaccac tccgtgatac catccaattc ttgtctgaca
    23281 cagttgacca gattatcgcc tacagtgctg agttggggga gtaaggggaa tagaaaaatt
    23341 ttttagaatg atgtttatgg gcttgttaag cgtcattcta tttgtcttag ttgtagctat
    23401 tttcaaaaat gtcgttgaag gtcgtgatgt taaatttgaa cttactgtag aactggtatt
    23461 gatagttatt tacgtcattt tatatcagat tgtatttaat tgagaattca atattgagtc
    23521 atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc atgtatcaag
    23581 atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa atccagtggt
    23641 tgcttgatca tttgggagat ccttctccag aaattcgcga tgaccttgtt tttacaagct
    23701 ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc attgctgaag
    23761 gggtttcatc tgatgtagga ctagataaag agattgataa ggtaggtctg ccaacacttg
    23821 aacgttcttt tagggcactt gtttatgcaa atctcttgta tgcagatgcc aaccagcaat
    23881 cggtttttta tcagggatta caattagaaa ttcgtaatgt cttttcaaat caaggcttgc
    23941 actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt tgggttcatg
    24001 cttttgcaca tggagccgat ttactgacag aggtggtctg tcatccagac tttcctataa
    24061 acagaattca tgaagtattt gacatacttg gccaactatt taaaagaatg tcgattcgct
    24121 ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt ttacaaggga
    24181 agttggagca agaacaagta gcttcttgga taaaaactgt tgattttccg atagaagaaa
    24241 gggaggattt ttccaaattt tccaacttta gatcctgtct ggtggaagtc tatgtccaac
    24301 ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct tttcaatact
    24361 agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt cttgaaaccc
    24421 tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga aaatgaaaaa
    24481 atttgttgct gagttaatcg gtacgttcat gcttgtgttc gttgggacag gagctgttgt
    24541 ttttggaaat ggttttgatg gccttggtca ccttggaatc gcctttgcct ttggtttggc
    24601 aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga acccggctgt
    24661 ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa actacatcct
    24721 tggtcaggtt gttggagctt tcatcgcttc tggcgctgtc ttcttcctct tggctaactc
    24781 aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca ctgtctttgg
    24841 tggtttcttg tttgaagtca tcgcaacttt cttgtttgta ttggttatca tgactgtgac
    24901 ttcagaaagc aagggcaatg gcccgattgc tggtttggta atcggtttgt cattgatggc
    24961 gatgattctt gtcggattga agattactgg actttcagta aacccagctc gtagcttggc
    25021 accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca tccttgcacc
    25081 aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa cagaagaata
    25141 attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc gtatgatact
    25201 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc gtaggtatgg tt
//
LOCUS       DBEJJE010000030        25030 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEJJE010000030 DBEJJE010000000
VERSION     DBEJJE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.30"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..270)
                     /locus_tag="ACL3F5_001276"
                     /pseudo
     CDS             complement(1..270)
                     /locus_tag="ACL3F5_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(332..781)
                     /locus_tag="ACL3F5_001277"
     CDS             complement(332..781)
                     /locus_tag="ACL3F5_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0515075.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(783..1541)
                     /locus_tag="ACL3F5_001278"
     CDS             complement(783..1541)
                     /locus_tag="ACL3F5_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0515076.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1656..3635)
                     /gene="stkP"
                     /locus_tag="ACL3F5_001279"
     CDS             complement(1656..3635)
                     /gene="stkP"
                     /locus_tag="ACL3F5_001279"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0515077.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3632..4372)
                     /locus_tag="ACL3F5_001280"
     CDS             complement(3632..4372)
                     /locus_tag="ACL3F5_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0515078.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4387..5700)
                     /gene="rsmB"
                     /locus_tag="ACL3F5_001281"
     CDS             complement(4387..5700)
                     /gene="rsmB"
                     /locus_tag="ACL3F5_001281"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0515079.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5693..6628)
                     /gene="fmt"
                     /locus_tag="ACL3F5_001282"
     CDS             complement(5693..6628)
                     /gene="fmt"
                     /locus_tag="ACL3F5_001282"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0515080.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMEIASFLNGVGRTLTVGERFGD"
     gene            complement(6641..9037)
                     /locus_tag="ACL3F5_001283"
     CDS             complement(6641..9037)
                     /locus_tag="ACL3F5_001283"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0515081.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQINFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QESNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMDCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9103..9417)
                     /gene="rpoZ"
                     /locus_tag="ACL3F5_001284"
     CDS             complement(9103..9417)
                     /gene="rpoZ"
                     /locus_tag="ACL3F5_001284"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0515082.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9442..10068)
                     /gene="gmk"
                     /locus_tag="ACL3F5_001285"
     CDS             complement(9442..10068)
                     /gene="gmk"
                     /locus_tag="ACL3F5_001285"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0515083.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10198..11811)
                     /locus_tag="ACL3F5_001286"
     CDS             complement(10198..11811)
                     /locus_tag="ACL3F5_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0515084.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEIKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12002..12256)
                     /locus_tag="ACL3F5_001287"
     CDS             complement(12002..12256)
                     /locus_tag="ACL3F5_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGR0515085.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(12260..12514)
                     /locus_tag="ACL3F5_001288"
     CDS             complement(12260..12514)
                     /locus_tag="ACL3F5_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR0515086.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12752..13849)
                     /locus_tag="ACL3F5_001289"
     CDS             complement(12752..13849)
                     /locus_tag="ACL3F5_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0515087.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEQGAEMENFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGYNIKLHPIQRQGAGYHSVDKDVNFASATALRQHQRDKDFLERFMPSVALFEQA
                     SKVSWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQVRESNLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13859..14599)
                     /locus_tag="ACL3F5_001290"
     CDS             complement(13859..14599)
                     /locus_tag="ACL3F5_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0515088.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFSMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14708..15061)
                     /gene="rsfS"
                     /locus_tag="ACL3F5_001291"
     CDS             complement(14708..15061)
                     /gene="rsfS"
                     /locus_tag="ACL3F5_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0515089.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15074..15574)
                     /locus_tag="ACL3F5_001292"
     CDS             complement(15074..15574)
                     /locus_tag="ACL3F5_001292"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0515090.1"
                     /translation="MKMAFIIIDVQNILVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15575..16168)
                     /gene="yqeK"
                     /locus_tag="ACL3F5_001293"
     CDS             complement(15575..16168)
                     /gene="yqeK"
                     /locus_tag="ACL3F5_001293"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0515091.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16168..16797)
                     /locus_tag="ACL3F5_001294"
     CDS             complement(16168..16797)
                     /locus_tag="ACL3F5_001294"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0515092.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16849..17160)
                     /gene="yhbY"
                     /locus_tag="ACL3F5_001295"
     CDS             complement(16849..17160)
                     /gene="yhbY"
                     /locus_tag="ACL3F5_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0515093.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17374..18480)
                     /gene="yqeH"
                     /locus_tag="ACL3F5_001296"
     CDS             complement(17374..18480)
                     /gene="yqeH"
                     /locus_tag="ACL3F5_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0515094.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(18483..19010)
                     /locus_tag="ACL3F5_001297"
     CDS             complement(18483..19010)
                     /locus_tag="ACL3F5_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0515095.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(19025..19933)
                     /locus_tag="ACL3F5_001298"
     CDS             complement(19025..19933)
                     /locus_tag="ACL3F5_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0515096.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19990..20550)
                     /locus_tag="ACL3F5_001299"
     CDS             complement(19990..20550)
                     /locus_tag="ACL3F5_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0515097.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20688..21897
                     /gene="sstT"
                     /locus_tag="ACL3F5_001300"
                     /pseudo
     CDS             20688..21897
                     /gene="sstT"
                     /locus_tag="ACL3F5_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21965..22918
                     /locus_tag="ACL3F5_001301"
     CDS             21965..22918
                     /locus_tag="ACL3F5_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0515098.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            23061..23441
                     /locus_tag="ACL3F5_001302"
     CDS             23061..23441
                     /locus_tag="ACL3F5_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0515099.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            23540..23761
                     /locus_tag="ACL3F5_001303"
     CDS             23540..23761
                     /locus_tag="ACL3F5_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0515100.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            23778..24092
                     /gene="trxA"
                     /locus_tag="ACL3F5_001304"
     CDS             23778..24092
                     /gene="trxA"
                     /locus_tag="ACL3F5_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0515101.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            24398..24931
                     /gene="queF"
                     /locus_tag="ACL3F5_001305"
     CDS             24398..24931
                     /gene="queF"
                     /locus_tag="ACL3F5_001305"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0515102.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDKR"
BASE COUNT         6788 a         5847 c         4953 g         7442 t
ORIGIN      
        1 ctcccttgac ttgtgacaat cgcttgagcc ttcatagcgt ggcatttctt tttaccagaa
       61 taattcgcta attgtttttt agggcgattg atttttactt ccgtcacatc aatcattacc
      121 atgtcctcag aactgagagg agttcttgaa attgtaacac cacctttgaa caagagttac
      181 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
      241 ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat
      301 ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat
      361 gatacagtct gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca
      421 tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag
      481 ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca
      541 cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg
      601 caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag attagccaga
      661 cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacgatta
      721 aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
      781 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc
      841 agggattcaa acatcttact cataccagag tttatgtggt tggtcataat atcacggacc
      901 gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct
      961 gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag
     1021 gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag
     1081 gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac
     1141 ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
     1201 ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc
     1261 cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa
     1321 gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg
     1381 gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg
     1441 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
     1501 atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa
     1561 ctccctctat tctatcacaa atctggactc aaaaaaaatc tttgccatga aatcatgaca
     1621 aagattgatt actcattttg attatccatc tgcttttaag gagtagctga agttgtttta
     1681 ggtttgtaga ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta
     1741 ggactttgtt caacaaccat gccttctgca ctacctgcag gcgctgtcgt cacttctaca
     1801 acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc
     1861 aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag
     1921 acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata
     1981 atcgttcctg gttcactttc gctggactct tcttcctcta tcttaatcaa attctcagga
     2041 accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct
     2101 aattgaattg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag
     2161 tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattg
     2221 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg
     2281 ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat
     2341 gagacaacca aattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
     2401 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
     2461 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
     2521 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
     2581 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
     2641 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
     2701 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
     2761 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
     2821 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
     2881 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
     2941 acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
     3001 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc
     3061 tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac
     3121 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
     3181 accttggccg tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
     3241 attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct
     3301 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtccag tccagccaca
     3361 tactccatag ctaggtactg ttgaccgtct tcctcaccaa tatctgttat ccgaacgata
     3421 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
     3481 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
     3541 aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga
     3601 tagcgtccgg caaaaatctt gccgatttgg atcattcttc atcctcctcg ttcatagaaa
     3661 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
     3721 ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa
     3781 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
     3841 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
     3901 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca
     3961 aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
     4021 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
     4081 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
     4141 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag
     4201 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga tgacctccca
     4261 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
     4321 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
     4381 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
     4441 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
     4501 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
     4561 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
     4621 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
     4681 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
     4741 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
     4801 agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
     4861 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
     4921 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
     4981 cgtcggagca accaactgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
     5041 attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta aaagggaatt
     5101 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
     5161 ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc
     5221 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
     5281 ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc
     5341 gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg cttcattaac
     5401 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
     5461 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
     5521 cagagtcagt ttacgggcta ccgttccata gaccagctcg gtcactaagc ccttgtctgc
     5581 tgccaaaagt tgacttccct ttagatgctt atttaaggcg atatttgaat atgcttggtt
     5641 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
     5701 caaatcgttc tcctacagtc aatgtacgtc caactccgtt gaggaaggaa gcaatctcca
     5761 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
     5821 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
     5881 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
     5941 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
     6001 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
     6061 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
     6121 ccaatttttc aaacaaggcg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
     6181 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
     6241 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
     6301 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
     6361 caaaagcagc agtcacaatt ccatctgctc ctagctttat aagttcttcc atctctggac
     6421 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
     6481 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
     6541 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
     6601 gggtccccat aaagattagt tttgtcatat cttctccttt ttataaaaat tgctgcggct
     6661 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct
     6721 ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat
     6781 agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
     6841 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
     6901 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc
     6961 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
     7021 catagtgctg cggattgtag gactgtatca agacttgacc tgccttttca gcccgacctg
     7081 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
     7141 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
     7201 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
     7261 gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc agaatgcgag
     7321 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
     7381 gaatactgtg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
     7441 aatggcagtc catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
     7501 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga
     7561 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
     7621 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
     7681 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
     7741 tgccagcacg cgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt
     7801 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctttcct
     7861 gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
     7921 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
     7981 attcatcata cttttcacca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
     8041 agcgtgctat aaaacgctcg gtcatttgag gagtcaagga aatctcaggt accagcaaaa
     8101 tagctgtctt gcccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc
     8161 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
     8221 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
     8281 cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca gcaccttgat
     8341 ccacaaagaa gttgatttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
     8401 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
     8461 tctcaacacc ttctaattga gcatggtcaa cctcatacca agactgggtc ttgaccttct
     8521 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
     8581 cagcttgctt ggcaaggtct agtgaagaaa aggctagcga atcttctgaa ccaaacaggc
     8641 gcactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat
     8701 tcagaaatcc tggaagcatg gccttgagga tagaaatttt gtaggagaag acagatttgc
     8761 gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct
     8821 ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac tccaaaccaa
     8881 gaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc cgcatcccaa
     8941 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
     9001 tcaagggcac atctacgata atcttagcta gggccatcgt ctcacctcct ccttgtcagt
     9061 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
     9121 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
     9181 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
     9241 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
     9301 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
     9361 tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
     9421 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
     9481 gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc
     9541 agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
     9601 ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg ttccacgacc
     9661 taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
     9721 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
     9781 tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt taccgacata
     9841 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
     9901 gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
     9961 agagtattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
    10021 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    10081 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    10141 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    10201 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    10261 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    10321 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    10381 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    10441 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    10501 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    10561 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    10621 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    10681 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    10741 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    10801 catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc
    10861 acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    10921 atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    10981 cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc
    11041 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    11101 agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt caccagcgat
    11161 acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgatctc
    11221 ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc
    11281 caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc
    11341 tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    11401 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    11461 acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg
    11521 ttctgattta aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    11581 caatagtgct tcttttttaa gagacttact ttcacgtttg gcttcattaa caagtaaatc
    11641 cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    11701 caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    11761 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    11821 tcattttatt gttattccga atgacataca ttcttttaca ttctaccata aaaaagggat
    11881 tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacattta ccaaaataaa
    11941 cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact ttgcagtaga
    12001 cttagtaatg atctttaaag gacaagaaag ccacgctatc tccatccatc atataaatca
    12061 agcgattttc tgcatcaata cgccgtgacc aggctccttg gtaatcatat ttgagtggct
    12121 ctggttttcc tattcctgta aatggatcgc gttgaatatc cttgattaat ttattgattc
    12181 tttttagtgt ttttttatct tggttttgcc agtagcaata atctgcccag gcatcttctg
    12241 taaacttgag tagcattcat cactcctcaa tcacatggac ctgagtgctt ccagcacgga
    12301 cttgagccat tcctcgcaaa accttgtctg ataactcctt attttgggcg attctcaggg
    12361 tttcctgaat actgtcccat tcgctctttg aaagaactac aatgtcctca tctggatttt
    12421 tattgaccac cgtcaaaggc tcaaattcat catttacctt cttcatgtag tcctttaaat
    12481 gatttcggaa tgttgagtaa aggactgctt ccataaccat acctcgtttt agctcttttc
    12541 cactattata cacgaaaaga aagaaattgt caggaacttg tacaagattt tcttttctat
    12601 ctatttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
    12661 agtacggcaa ggcgacgttg acgcgatttg aatttgattt tcgaagagta ttattcgtaa
    12721 aaaatctcaa aaagcctacc tttcggtaga cttagtttgt ttctattcta atcggcactc
    12781 ttccaaaatt ttgctctgct atacttggct ttcctagttg gtaaatctgg tctgcttttt
    12841 gggtcatagc atcccaaggt tctttgccaa ttcggctgac tagactgacc tgacctttca
    12901 aagatttgag atgttgcctg cctttttcag taaatccaag gacatgaatc gcttctggca
    12961 agttactttc tctaacctgc accaaaatat aggtcaatag gcgtctgaca cgcgccttgg
    13021 tgtaacgttt ggtagtcact aactcgacca attcttccac agactgggct gttttaatag
    13081 cttctttaat gcgcacagcc atttcttgat tgacctgata gatggtggtt aggtcgggat
    13141 ttgacaagat ttgatagcgg agcaagggaa aatagtcttc ccagctcacc ttactggcct
    13201 gctcaaagag ggcaacagaa ggcataaatc gttctaagaa atctttgtcc ctctggtgct
    13261 gacgaagggc tgtcgccgaa gcaaagttca catccttgtc cacagaatgg tagcctgccc
    13321 cctgacgctg aatcggatga agtttgatgt tgtacccagc aaccgccttg gcgtaagcga
    13381 gggcaagaac atgattgggc gtattgcctg aaaaatcaag acctgcaaat tccttccaca
    13441 tggcttgggt cttctgggga taagaaagag agtcaggcaa attttccaca aaattctcca
    13501 tctcagcccc ctgctctgtg tataagtcag cgattttttg ataatctaga acttcttctg
    13561 tcccaaaagc gaggctatct atgcccaacc gagctaagat atccacggcc ccttgaccga
    13621 aaaaatctgc cgcctgaacg ctgactaaaa agggcaattc cactaccaga tccgctccat
    13681 tttccagcgc catctgggct cgtgtccact tatccacgat agcaggttct ccacgctgca
    13741 tgaaattccc tgacatagcc acgattttca gcccctccgc ttgatccagc aggtatttgt
    13801 gtccattatg aaaaggattg aactccgcga taatacccgt gatggtcata gtaatctcct
    13861 acttctgcgc cacaaaaaac caacgggtgc tagtttctgt tggctcctta tcctcaaagt
    13921 ctgcatagag tttgaaggac ttgaatccag cctgttccag caagatatca taggtcaaga
    13981 tctcataggt cctctcctca tgtacttcat cgtggcgact aaaggaaccg tcagcctcct
    14041 tgataaagaa agtcagctca tgcacgatgg agtgaggagc ttcgtcctca tatgtatccc
    14101 aaagcatgga aaaatcttcc gcattttcat ggtaggaata gccagggaat acttcatctg
    14161 tctggtaggt cgagtgcacg tcaaagatga aaactccctc ttcattcagc gcattgtaca
    14221 cgtccttaaa gacgtcccct acttccacct catcctgcat atagcagata gagtccgaat
    14281 aacacgtgac aaaatcgtat ttccctgcct tggacaaatt cagcatatta ccttctataa
    14341 aagcaatctt ttgcttggct gaagttgctc tcttctccgc aatcttcaac atatccgcac
    14401 tcaagtcaag tccagtcaca tcaaaaccag cctgagagaa gcgcactgat tgaattcctg
    14461 tcccacaagc cagttccaag agtttctttc tctccttggt cttaggcaaa tgacgcagag
    14521 aaaaattcgt ccatttgtcg tataaactat cgtccatgac cgcatcatag accgccgcaa
    14581 aggtttcata agtcgccata atcatgatac taagagctcc atggtaaaca ccactagccc
    14641 tttacctttc tatcaatttt tctaaaataa gcaaagaaac ccagttgact acaactgagt
    14701 tcatcttcta agcaagagct tctgaaatat ctactgaatt cgcctcatgc catagcttct
    14761 ctagattata atgggcacgc atttcttctg aaaagatatg cacgacaaca gcaccgaggt
    14821 ccagtaagac ccagcctcca gctgcatcgc cttcgacatg gctaccttta aagcccgctt
    14881 gagctacttt ttcacggata ttagctgcga tagcgtccaa ctgacggcta ttcattgagc
    14941 tagtgatgac aaagtagtcc gtcacactag tcaaatcttg tacatcaagt gcgaggatat
    15001 cctccgcacg tttctcatca gccgctttca cgactagttc tagtaattct ttttcgttca
    15061 tttaatcctc tttttagaaa atatgtttgt aatctaggac atctgcaaag cgctcctccc
    15121 aaatgtcctc ataaaattca ttaatcgttt ctgctggaat gtcatcccca tcaaaggttg
    15181 tgacagcacc ttctggaaca ataagctgat agccatattc aaaggcaacc ttgacagaag
    15241 tatccacaca atattctgtc tgcataccac ataaaactaa tttttcaatc ccctgtttat
    15301 ccaagtattc ttttaagcca gtttctttga aaatactgtt atacttcttc tgaaagacct
    15361 tttcagcagg ttttcgattt aaaagcgcag ataactgcca atcttctgat gtttgagctt
    15421 cagagttctc aatatgttga acatagataa tttcaatatt cttgcttcta gcctggtttt
    15481 gtaaataaga aattttttcc aatagacttt ttgtctggaa cccagtttct actaaaatat
    15541 tctgaacatc aatgattata aaagccatct tcatttagtt ctctttcaaa tagtgcacaa
    15601 aggcgttata ggtttcaagg gtttggggat agatggggaa tccctgatga gctagatact
    15661 ccacggtacg agctgtttcg taggccaccg ccttattgag cgatagactt gcaatctcac
    15721 gcgccacatc tactccagga aaggctcgat tgtgctcgat atagtctgcg acgtagatga
    15781 ccttatctag gtctgtcatc tgaccagcac cgactgtatg gacttcaatg gctcgcagga
    15841 tttctgaatc atgcaaatcc aaatcttcct gaattttgta aattccgacc ataccatgcc
    15901 agacattatt accccagttt ttgaggtcga aatctagctg ataacggtca atcaagtcta
    15961 gaaattcctg atctgacaac tttttagcat agtcatgaag aagacctgct agacttgctt
    16021 tctcaacatc tacaccaaag cgctgagcta attccatagc ggcacgctcc acacctagac
    16081 aatgggttag acgtttctca ggtagaagct ctgccatttt ttccaacaag gcctcacggg
    16141 agcagttgat atagtcttga taggacatca gtagagcccc tccttctcga tgtagtctag
    16201 cactggctga ggtaggagaa agttgggttt ccgaccttgg gcaaggaagt cccgcaccat
    16261 gctggacgag atatccatga gcggtacgtc cacccagata actggatagg aagtccctgc
    16321 cttgtagcgt ggacgctgaa cccccacaaa ctgaaccatg tcaaccagtt catcaattcg
    16381 gtaccactta ggcagatagt caaccatgtc ggcgccgatg ataaagtaat aatccgtatc
    16441 tggatgttgc tctgtcaaga ttttcatggt gtcgtaggtg taggaaatac ccttgcgctc
    16501 caactcaata gtttcaatga ctaggccgtc aatcccctca attgccaact caagcatctt
    16561 gagacgatgg tgttcaggga tggtttcctt tttatcaacg tgaggaggtt ggtattcagg
    16621 catgagcaga acttgatcca gtcccaactg ttgccgtact tgatccgcaa caatgagatg
    16681 ggcattgtga acagggttaa aattcccccc taaaatccca acttgtttgc gttttttctc
    16741 cttgatttct ggctccaact ctaccttggt aaagggagtc aatagttcga ttgtcatagg
    16801 ctagtcccct ttatttctct ataaaaacag ttatttggag tttcggtctt agatttcttt
    16861 gactttctta gaaatcttgc gattttcttt cttgctagat tgtttaaaca aaatcaagat
    16921 gcgtcctatt ttttggactg tatccacacc gatttcttct tccaaaattt cagctacttc
    16981 gtggatgttt tcatctgtgt tttgtaagag agtaaccttg attaattcac gcgcatcaag
    17041 agcttgacgg acgctggttt tgatttggtc gttgagtcca tttttcccga tttggatgat
    17101 aggtttgagg gtgtgtgcct ggctgttgag gaaggcacgt tgttttgatg ttaatgacat
    17161 aattttcttc cttgtttttt gatagttatt ttaggtggtg agggacggtc ggaactaatt
    17221 ttccaaagat ttcatctttg aaaaatggat ttcctgacct cacaattgag ccttggtctc
    17281 aattgtgccc cttgccaatc tacagattgg caatcacacc acggcaataa ctatcgctat
    17341 atgagctcac tttgttcgct cagcgatttt gttttaaata attgcttttc gtgtgacgac
    17401 ggcgacgcct tctggtgccc agacggcgac ttttgctatg cctgttacac gaatccagcc
    17461 taggcctgag atgactaggt ctgtcttatc tttaatggta aagacatgct ggactagcct
    17521 tgggaaatct tctttttcct tgctatttgg tggtgtcaga agagttccca ggtgcttatc
    17581 gtagaaagca ctagctcctt caagcttgct acgatggagt ttgagttcat tatcaaagaa
    17641 agcagtaaat ccttgctttt ctcctgctat aaagtcaaag cgtcccaaac cacctaaaaa
    17701 tagggtttgc tcaggattaa gctgataggt cttaggcttg atttcctttt taggactgac
    17761 atacttgagg tttttggccg tcaagtagtg agccatctgg tggcggtgga taattcccgg
    17821 cgtatcgtaa atataagatc cgtcgtcaag cggaatctct attttgtcca aggttgtacc
    17881 tgggaagcgt gaagtagtga tgacattctg atcacccgtg atttcttgga taatagcatt
    17941 gattagagtt gattttccaa cgttggtcac accgaccaca tagacatcgc ggcccttacg
    18001 gtagtgttca atcttgtcaa tgacttcctt aatggcatgt ttattttgtg ctgaagttag
    18061 gaccacatcg actggacgaa gaccttcttc atgggcacgt ttcatgagcc actggctaat
    18121 cttaccagac ttaactgact taggaaggat atctttttta tttcctacca agaggacatc
    18181 attgcccgag acgaaacgtg gtaaacctgg gatgacagat ccattaaaat caaagatatc
    18241 aatgacattg accactaagg catcactgtc tcccacctcg tgcaagagct tgaggaaatc
    18301 atcgttcgtc aactggacat ctgtgatttc attgtagtgg cggagacgga aacagcgttg
    18361 gcaatagact tcgccagtct ccaaaccttt ttcaagtgcc gactgggggg taaaaccaag
    18421 accagcttta tctgtcgtct gaatggttgc tccacaacca atacagagaa tttcttccat
    18481 agttaaattc cttttttata tgtaatcggt ccgtactttt cagtgatttt tctcataaca
    18541 cgacgctcac gagttcggtt aatctgcgtt ttgattgagt catgttggac caagggtttg
    18601 actaaaattg accgaatccc tgcacggtgg gctgctcgta tatctgtcat gagctggtcg
    18661 ccaaccatga ccacttcctt tttgtcatag tggaattcct tcatagcacg gtcaatacca
    18721 aatgtgaagg gcttcaaggc ccagtaaacg taatcaatcc caaatttctc aactgctcgt
    18781 tgaacgcgtt ttttggtgtt atttgacact acgataatgc caatacccgc gtcccgaagg
    18841 tcatgtagcc attgcttcat ctctggcgtt ccatcagggt tgttccaagc aatgagggta
    18901 ttatccaaat cgaccaaaac agccttgatt ccctgcgcct gcaggcttgg gactgtcaga
    18961 tcatagactg cttccacagc aaaatctggt atataatttt caatcgccat tctggctcct
    19021 tttcttaact ttttttcgca attttcctta gtaacaagga taaaacaatc cacaaacctg
    19081 cactagccaa actgatatag agccaagcat ggggctcatc tgttaaaggt aagggaacat
    19141 tcattccgaa aaagcctgtc acgactgcca aaacagctag caagactgaa atgatagtca
    19201 aggttgtcaa attgtcattc agattattgt ttagaatatt gttgtaagag gctgaaagct
    19261 gctgtaaaat ctgagagatt aggtctgtca tggataccag ctgatgagcc tcaatcatgg
    19321 catcatcaaa ctgttctctc tcaatctcat caaaactacg atacaaggca tgaccttgaa
    19381 tatgctctaa caaaatccga ttttgtttgg cagctgccgt cagataaacc ataccagtct
    19441 ccaaatcaga cagggcaaag aggtttttct tggtagttcg ctggcgcaag aggtcattga
    19501 cctcatccct actcttgtcc atctgctcaa tgacaggata gtaggcattg ctgataattt
    19561 ccagactggc aaagagaaac ttataaatcg aaagcgtgtc atggctctcc agataacgag
    19621 tcatctgttc aatgacatag gcgttcttgg tattactaat ggtaatcagg cgacgatgct
    19681 cgacaataaa ggtcatggga aaagtctcat agtaggcctt gtcctttttt acgtctagga
    19741 cattatagat aaaggtaacc gtcccacttt cacggtggta atccatgtgg gcgcgctcgt
    19801 ttctatccag tgcgtattca atggtttcct tgtccaaacc gtaaatttca gaaaggtctt
    19861 ctagtttatt caactttcct aggtctaggt ctatccaggt acaaccattg cccaactgct
    19921 tttctaaaac catcttttct ccttattaaa ctccctctat tgtaccacaa attacttaaa
    19981 ataacaggtc tagtctgtgc gtgagaaatt gctaacaact gtgatatttc ggttagggac
    20041 aaagtgaagg gcttgctcct cgctacgaag ctgtgtcgta cgaattccca cactgacaac
    20101 cttacccgat acagtaatcg gtccatttgt cagaacgacc tcatctccca catccagttg
    20161 acgttcaaag aggatgaaaa agccattgat gacatcagac agaaagcctt gggctcccat
    20221 accaatcgct accccagcaa taccagctcc agccagcaaa ctagaaactg gcaaacctaa
    20281 aatcgacaaa atgcagtaga gtaaaaagaa atatagcgta taattaaaca cattttctag
    20341 taaacgtgag atggtttttt ggcgtccgac atcatgacga gacattttta gagaaggttt
    20401 gacaattctc tgcaccatgg tatgaagcat ttttttagca atataaaata caatcaaaag
    20461 cagtaaaaga gaaatgacct tggttagaat attctcgata atggttgtca catctagctt
    20521 ttcaatataa gcctgaataa atttttgcat ataaaactcc tttatttcat tataccatat
    20581 tttcatcagt ctcattctcc ataaatattc aaaaatagac agaaaattct tgattttgtc
    20641 tatcatttat actataatca taatcactac acaaaaagga gattattatg aaaagaatca
    20701 ttcatgcttg gaataaggca agccttgtca agcgtatctt gattggtatg ctttgtgggg
    20761 attcctagga ctgacccttc ctaatctctc agggattggg ctactcgggg atttattcgt
    20821 tggagctcta aaagctgttg ctcctatcct agtctttgcc ctcgttgcca atgccctttc
    20881 ccaacatcaa aagggacaag atagcaatat gaaaactgtt gttttcttgt atatcctatg
    20941 atagggactt tcgccgctgc tcttgtagct gtactagcaa gtttcatcgt ccctattgaa
    21001 attaccctaa atagtgccaa tactgaaatt gcaccaccag atgggattgg gcaggtcctc
    21061 agcaacctct tgctcaaact ggttgacagc ccagtcaacg ccctgcttac tgctaactat
    21121 attggaatct tatcttgggc agtcattttt ggaatcgcta tgagagaagc cagtaaaaat
    21181 agtaaagaat tgctaaaaac tatcgctgac gtgacttcta aaattgtcga atggatcatc
    21241 aatctggctc catttggaat ccttggtctt gtttttaaaa ccatttctga caagggagtc
    21301 ggaagccttg ccaactacgg tattttattg gttccattag taacgactat gctttttgtt
    21361 gcccctgtgg tcaacccttt gattgccttc ttctttatga gacgcaatcc ttactctcta
    21421 gtttggaact gcctccgtgt cagcggtgtg acagcctttt tcactcgtag ttctgcgact
    21481 aacattcctg tcaacatgaa actctgccat gaccttggac tcaacccaga tacctattct
    21541 gtttctatcc cactcggttc tactatcaat atggctggag tagcgattac cattaacctt
    21601 ttgacccttg ctgcagttaa cactcttgga attcctgttg actttgccac agcttttgtc
    21661 ctcagtgtgg tagcagctat ctcagcctgt ggtgcttcag gtattgccgg aggttccctc
    21721 cttcttatcc cagttgcttg tagccttttc ggtatttcta acgatattgc catacaagtt
    21781 gttggggttg gttttgtgat tggtgtcatc caagactcat gtgaaacagc ccttaactct
    21841 tctacagatg gcctctttac cgccgttgcc gaatacgcag caacccgtaa aaaataactc
    21901 atcaaggcaa gcctgctcat gtcttgtctt ttacgctttt attctaactt attaggaaat
    21961 tcttatgtct attagccaac gtacgaccaa gctcatctta gctacctgtc ttgcctgcct
    22021 gcttgcttat tttctcaatc tttcgtcagc agtttcggct ggaattatcg ctctcttgag
    22081 cctatctgat acgcgtagaa gtactttaaa actggctcgc aatcgtcttt tttctatgct
    22141 tctagctctg gctattggtg ttctagcttt tcacttgagc ggatttcata tctggagtct
    22201 cggcctctat ctggccttct acgttccttt agcctacaag atgggctggg aaattggcat
    22261 cacaccaagc actgttttgg ttagccatct cttggttcaa gagtcaacct ctccagacct
    22321 tctagtcaat gaattccttc tctttgctat tggtacagga tttgccttgc ttgttaatct
    22381 ctatatgcct tcacgagaag aggaaatcca gcactaccac acgctggtgg aagaaaagtt
    22441 aaaagatatc ctccagcgct tcaaatacta tttatccaga ggagacggac gcaaccgagc
    22501 acagctggta gcagaattag acacgctttt gaaagaagcc ctcagactgg tctatttgga
    22561 tcactctgac cacctctttc accagaccga ctaccatatc cactactttg agatgagaca
    22621 acgacaaagt cgtatcctga gaaacatggc ccaacagatt aacacttgtc accttgccgc
    22681 cagtgaaagc ctgatcttag cgcaactctt ttcaaaaatt gcaggtcaac tgagccagac
    22741 caatcctgct tctgatttgc tagatgaaat tgaacgttat ctggaagtct tccggaaccg
    22801 cagtctgccc aagacaagag aagaatttga aacccgcgcc acccttcttc aactcctacg
    22861 tgaagccaaa accttcatcc aagtaaaagt tgacttttat caaaaatata gacagtaaaa
    22921 aagaaaacca ctaaaaaaca gagcttgcca gcattcttga aaagtagtat aattattgca
    22981 tgcgcaatca tcttgtgacg cagagactgc ccgttaatgg actttcttct atttatgact
    23041 ctaaaaagaa aggagacact atgacctatt tggaaaaatg gtttgacttc aatcggcgtc
    23101 agaaagaaat tgaaagtctc ttggaagaga ccattgccca acagagcgag caaagtctga
    23161 ccttgaaaga gttctacctg ctctactatc tggacttggc tgaagaaaaa tctctacgcc
    23221 agattgatct gccagataag cttcatctga gtccaagcgc agtttctagg atggtggctc
    23281 gcttggaagc taaaaattgc ggtctactca gtcgcatgtg ttgccatcaa gatagacgct
    23341 ctagttttat ctgcctgacg aatgatgggc aaaagacact ggcctcgcta caaaagactg
    23401 tcgaagaaag cttggaagca ggtttggatt tcttgattta agatgatttt agaaaaagtt
    23461 gcgtgcgcaa tcatttttct tgacattctc ttttataagg agtaaaataa agttagcatt
    23521 aaacaaagga gttttaaata tgattgaaat tacctatata gatgccagca agaacgaaag
    23581 aactgtgact ttcgagtctt atgaagactt tgaacgttcg caacaagctt gccttatcgg
    23641 cgtcgcagac tactaccctg tccaaaaatt aacttacaag ggtcataatt tggactacca
    23701 tgggacttat ggagatatct tcttctatct catgaaacaa gatttaagcc aatataacta
    23761 aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc aacattcgaa caagaaacaa
    23821 aagacggttt ggtcttagta gacttctggg caacttggtg tggtccatgt cgtatgcaag
    23881 gtccaatctt ggacaaattg tctgaagaac tttcagaaga tgtcttgaaa atcgttaaaa
    23941 tggacgttga tgaaaatcca aacacagctc gtgcttttgg aatcatgtct attccaactc
    24001 ttctcttcaa aaaagacggc caagttgtca aacaagttgc aggtgttcac acagcagaac
    24061 aaatcaaggc catcattgct gaattgagct aatcaaacga gagaccaagt actttctttg
    24121 gtctcttttt tcttgccctt tgccattttt caaaaaatat gctagactat agtagattga
    24181 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
    24241 tcgatttgtc ctgttcttat ttcattttac tatataagta gaatattacg atgtttggga
    24301 tatgccatcg ctaaaaaaac ctcgatttgg tattttttag ctccctaatg ggagcttttt
    24361 gcgtgctctg aacatttccc attttggaag gagtactatg aaacgtcaat cagccttggt
    24421 cgtctttagt ggtggtcaag attcaacaac ctgccttttc tgggccatgc aacactatga
    24481 aacagtcgaa gctgtcacct ttgcctacgg ccaacgtcat cacctcgaaa ttcaaattac
    24541 tagagaaatc gctaaggaac agggcattcg tcaccatatc ctcgatatgt ctctgctggg
    24601 acaaatcact gctcagccag actttgcgac gattcatatt tcctacattc ctgacaagct
    24661 ctgtgtcgag tcaaaatccc tcaaactata tctatttagc taccgaaacc acggagattt
    24721 ccacgaaaac tgtatcaaca ccatcgggaa agacttggtc aacttgctag accctcgcta
    24781 tttagaagtc tggggaaaat tcactccgcg cggtggcatt tcaatcgacc cctactacaa
    24841 ctacggtaag caaggaacta agtatgaggg cttggcagaa caacgcctct tccaacacga
    24901 cctttatcca gagaaaattg acaagcgcta aactcatact caatgaaaat caaagagcaa
    24961 actaggaagt tagccgcagg ttgctcaaag cagtgttttg aagttgtaga tgaaactgac
    25021 gaagtcagct
//
LOCUS       DBEJJE010000031        24136 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEJJE010000031 DBEJJE010000000
VERSION     DBEJJE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.31"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(45..278)
                     /locus_tag="ACL3F5_001306"
     CDS             complement(45..278)
                     /locus_tag="ACL3F5_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0515103.1"
                     /translation="MTKKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(284..1276)
                     /gene="plsX"
                     /locus_tag="ACL3F5_001307"
     CDS             complement(284..1276)
                     /gene="plsX"
                     /locus_tag="ACL3F5_001307"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0515104.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YSKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1273..2043)
                     /gene="recO"
                     /locus_tag="ACL3F5_001308"
     CDS             complement(1273..2043)
                     /gene="recO"
                     /locus_tag="ACL3F5_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0515105.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2040..3209)
                     /locus_tag="ACL3F5_001309"
     CDS             complement(2040..3209)
                     /locus_tag="ACL3F5_001309"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0515106.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3358..4368
                     /locus_tag="ACL3F5_001310"
     CDS             3358..4368
                     /locus_tag="ACL3F5_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0515107.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(4596..5033)
                     /locus_tag="ACL3F5_001311"
     CDS             complement(4596..5033)
                     /locus_tag="ACL3F5_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0515108.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5118..7751)
                     /gene="polA"
                     /locus_tag="ACL3F5_001312"
     CDS             complement(5118..7751)
                     /gene="polA"
                     /locus_tag="ACL3F5_001312"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0515109.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQPYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8007..8914
                     /locus_tag="ACL3F5_001313"
                     /pseudo
     CDS             8007..8914
                     /locus_tag="ACL3F5_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            9041..9322
                     /locus_tag="ACL3F5_001314"
                     /pseudo
     CDS             9041..9322
                     /locus_tag="ACL3F5_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(9456..10424)
                     /locus_tag="ACL3F5_001315"
     CDS             complement(9456..10424)
                     /locus_tag="ACL3F5_001315"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0515110.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10569..11383)
                     /locus_tag="ACL3F5_001316"
                     /pseudo
     CDS             complement(10569..11383)
                     /locus_tag="ACL3F5_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(11408..11905)
                     /locus_tag="ACL3F5_001317"
     CDS             complement(11408..11905)
                     /locus_tag="ACL3F5_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0515111.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(11978..13342)
                     /gene="radA"
                     /locus_tag="ACL3F5_001318"
     CDS             complement(11978..13342)
                     /gene="radA"
                     /locus_tag="ACL3F5_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0515112.1"
                     /translation="MIAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEIEVAEVK
                     NARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGK
                     STLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEV
                     ERIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE
                     GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLN
                     PSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASL
                     IMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVG
                     ELGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLK
                     KVFA"
     gene            complement(13353..13868)
                     /locus_tag="ACL3F5_001319"
     CDS             complement(13353..13868)
                     /locus_tag="ACL3F5_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0515113.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSDMGRQQVQKLSK
                     NPLLSSAEIIVSSAVARALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENRGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(13870..14313)
                     /locus_tag="ACL3F5_001320"
     CDS             complement(13870..14313)
                     /locus_tag="ACL3F5_001320"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0515114.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(14598..14963)
                     /locus_tag="ACL3F5_001321"
                     /pseudo
     CDS             complement(14598..14963)
                     /locus_tag="ACL3F5_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
     gene            14983..15150
                     /locus_tag="ACL3F5_001322"
     CDS             14983..15150
                     /locus_tag="ACL3F5_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGR0515115.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(15531..15722)
                     /locus_tag="ACL3F5_001323"
     CDS             complement(15531..15722)
                     /locus_tag="ACL3F5_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0515116.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            15787..16026
                     /locus_tag="ACL3F5_001324"
     CDS             15787..16026
                     /locus_tag="ACL3F5_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515117.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            16440..16808
                     /locus_tag="ACL3F5_001325"
     CDS             16440..16808
                     /locus_tag="ACL3F5_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0515118.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            16808..17041
                     /locus_tag="ACL3F5_001326"
     CDS             16808..17041
                     /locus_tag="ACL3F5_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515119.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            17041..17304
                     /locus_tag="ACL3F5_001327"
     CDS             17041..17304
                     /locus_tag="ACL3F5_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0515120.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            17317..17697
                     /locus_tag="ACL3F5_001328"
     CDS             17317..17697
                     /locus_tag="ACL3F5_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0515121.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            17714..18784
                     /locus_tag="ACL3F5_001329"
     CDS             17714..18784
                     /locus_tag="ACL3F5_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGR0515122.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            18845..19981
                     /locus_tag="ACL3F5_001330"
     CDS             18845..19981
                     /locus_tag="ACL3F5_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0515123.1"
                     /translation="MEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAIL
                     LQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIEGD
                     YLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFVET
                     PRKVITSDELKKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMRYG
                     ELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQII
                     ENATNGFDTDFIFINTLGEPITNARVICALKRHGQKIGIEKNITTHTFRHSHISLLAE
                     LGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLDKIKF"
     gene            complement(20064..20157)
                     /gene="ffs"
                     /locus_tag="ACL3F5_001331"
     ncRNA           complement(20064..20157)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3F5_001331"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(20190..20657)
                     /gene="tadA"
                     /locus_tag="ACL3F5_001332"
     CDS             complement(20190..20657)
                     /gene="tadA"
                     /locus_tag="ACL3F5_001332"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0515124.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(20858..22144)
                     /locus_tag="ACL3F5_001333"
     CDS             complement(20858..22144)
                     /locus_tag="ACL3F5_001333"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0515125.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(22375..22611)
                     /gene="comW"
                     /locus_tag="ACL3F5_001334"
     CDS             complement(22375..22611)
                     /gene="comW"
                     /locus_tag="ACL3F5_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0515126.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            22853..23650
                     /locus_tag="ACL3F5_001335"
                     /pseudo
     CDS             22853..23650
                     /locus_tag="ACL3F5_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23685..23894)
                     /locus_tag="ACL3F5_001336"
                     /pseudo
     CDS             complement(23685..23894)
                     /locus_tag="ACL3F5_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24060..24133)
                     /locus_tag="ACL3F5_001337"
     tRNA            complement(24060..24133)
                     /locus_tag="ACL3F5_001337"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24097..24099),aa:Asn,seq:gtt)
BASE COUNT         7580 a         5610 c         4152 g         6794 t
ORIGIN      
        1 atttctaaaa accatctact tccgttgact tggaactccg attgctattt tccttgaatg
       61 attttaacca catctcctac gttttggagt tggtcaattt cttcatcgct gatttcgata
      121 ctaaattcat cttccagagt caagataaac tccatcaagt caacagaatc cgcatccaaa
      181 tcgtctttca gactcaagga ttctgtcacg acaaagtcct ctccctgtcg ctcttggata
      241 atggtcacaa tacggtcaaa aatttctttt tttgtcatct cttttattct cctgaaaatt
      301 cacgcgcagt ctgggcaacc acgtctgttt ctagcatggt acggatctga cgaatcgtac
      361 tataaacagc cttggcatcg cttgagccat gagtcttgac aacaggtgcc ttaacaccaa
      421 acaagaccgc tccaccaaca tctgaataat tgagctgttt tttcaaacca ctgaggctgt
      481 ccttgagaag gagggcacct agtttcgctc gaagaccacc acctgtaata gctgtcttga
      541 gcaagcccat gattcccata gctgtccctt cgatggattt gagcacagcg tttcccgtga
      601 aaccatctgc cacaacaaca tctgcaacgc cattcatcaa atcacgcgct tccacgtttc
      661 cgataaagtt caaactttca tcagccgcca gtaattcata agtttcctta cgaagcgggt
      721 cgcccttgct actctctgtt ccgttgttga gcaaaccaac gcgtggttgc gcaatgccac
      781 ggacattttt agaatagaag gaacctagaa ccgcatattg atggaggtgc tgggctgtat
      841 tttctgcatt ggcaccaagg tctagcatgt caaaaccttt tccatcaacg gtaggcaagg
      901 tagacatgag tccaggacgg tcgatattct tgatacgacc cacgatgaag aatcctgctg
      961 ccaacaaggc acctgtattc ccagccgaaa ggacagcgtc tgcttcacca tctttgacag
     1021 ccttggctgc caataccata ctggcatttt tcttattcct aatagctctc gtaggttcat
     1081 catccgaatc aatcttctca tccgtatgga taatgctgac gcgctctgtc gctgtcagat
     1141 attgcttgat tttagcttca tctccgtaaa gttgaacctc gatatctgaa aagtcagata
     1201 gggcttgatt gacaccctca acaatggcct gaggtgcgta atcgcccccc atggcatcta
     1261 ctgcgatttt tttcatttct tttcctcttt tagtaattgt ccccagtctg ctagggaatc
     1321 aataaatttc tttgatttta ggtgaatccc aacgtactct tcatataatt gatccataaa
     1381 ttggcgtagc tcttgcttga ttccaggctt gagcgaaatg gtctccaaag tctcaaaatc
     1441 aatagcttga aattgattga gcagataggg gatattggga ttgagatgac aacgtctctt
     1501 atcctcatga taatgctctg gacagaggca ggctccatat ttgaaagaaa agtcaaaagc
     1561 ctgaccaacc cgatggcaga agacacactc attaaaattg aggctgattc caaatcgagt
     1621 caaaatttga atttcaaaaa tattggtcaa aacctgataa tccaagcctg cttccatcaa
     1681 ctccaaagtc ttttgcaaaa aagcaaacaa gggagcatcc tgctgattgt cctgcaaact
     1741 agcatctgca agagctgcca cataggtcgc ataggccatg acaaagaggt cactattaat
     1801 cttgggaaaa gtcatgacct catgatagtc ttcgatgtaa ctgagtccgt catcattgat
     1861 tcgcaagaga aatcgtgcca gcaccaaggg ctgaataaca ggcgccagct tagactgacc
     1921 agcgtgtttg acaaaaaaca tgcgtttgcc aacctgctct gtaaaaattt tgacgagctt
     1981 gtcatcctca cgaaaattgc gattgtaaag caccaagcct tgactcgtga tagactgaat
     2041 catgcttctc tcatgtactc ctcaagtcgt ttcatggctt ctttgatagt ctccatgctg
     2101 gctgcataag ataggcggac gtagccttcc ccgtaacgtc caaaggctgc accagggata
     2161 aaggcaacgg ccttcttctg agcaaaatcc ttcagaaaag caaaggagtc ttgattgtag
     2221 cccgctggaa ttttagcaaa aatatagaag gcaccgtctg gtttgataat ctcaaaacca
     2281 agagcagtca ttttttcgat gatatagtcc cgacgctgga tatattcctt cttcatgggc
     2341 tccgcatcat ttttaccagc cgtcaaggct tctaccgcag catgttgcgc catggtattt
     2401 gcggcagtga ccaagtattg gtgactcttg attaactggg ctgtgaaggc cgcaggagcg
     2461 aaaatcagcc ccaaacgcca acctgtcatg gcatgcgatt tagacaaacc attgataata
     2521 atagcctggt ctctcaacat cgttcctaga gacacatggg cttcgcctgt gtaggtcaat
     2581 tctgagtaaa cctcatcaca gacaacaaaa atttcgtact tgcgtaaaac agctgccaag
     2641 gcctctaact gctctcgact gtaggtaatt cctgtcggat tggctggata gttgagaata
     2701 accgccttga gcttatcacc ctgctccaaa atggccttct ccaacatctc aggagtcaag
     2761 acaaaaccat tttcagtcgt atcaatctca acaatttctg ccccaactaa gttaacaatc
     2821 ggttcatagc ctggataagc aggagctggc aaaagtacct tgtctccctc ttccaaaata
     2881 gccgtcaaag tcgcagataa agcctctgtc gccccaattg taaccaagat ttcattttca
     2941 ggagcatagt ccagttggta cttttcctta acaaagtcac tggctgcctg acgtagagtc
     3001 agcagaccac tcatccctgt atagtaggat tggttctgat caatcgctcg cttggccgcc
     3061 tccttgacat ggtctggcgt tgtaaaatca ggttccccca aggtcaaacg caagacccca
     3121 ggaatctccg aaataacctg gtcaaactga cgaatcaacg aaacttgaat tttatctaac
     3181 tgtttattaa agcgcttagt taagtccata gatacctcct actttcaaaa cgtatctcta
     3241 ttatactaca aaagcccccc gaccgcaaaa atacattaga gaatagcttt ccactttcta
     3301 ttttactttt cctgtttaca ggtctataat ggtaacagat tctatttgga ggtttttatg
     3361 tcatttctat caaaaaatgg agcaggcatc ttggtctgcc ttctcatttc tatcgtatct
     3421 tggtacttag gaggattctt ccctgtgatt ggcgcgcccg tttttgcgat ttttatgggc
     3481 atgctcctac atccctttct ctcgtcttat aaacaactgg atgttggatt gacctttagt
     3541 tccaagaaat tgctccagta tgccgttatc ttgcttggtt ttggtctcaa tatctctcaa
     3601 gtcttcgcag ttgggcaatc ttcactccct gtcatccttt ccaccatttc aatagccttg
     3661 attgttgcct acctcttcca gcgcttcttt gccctggata caaaactggc taccttgatt
     3721 ggagtaggtt cttctatctg tgggggttct gccattgcag cgacagcgcc tgttatccat
     3781 gctaaggaaa aggaagtagc ccaagccatc tccgttatct ttttcttcaa tgtcttggct
     3841 gcgctcatct ttccaaccct cggcacctgg cttcatctat ccaatgacgg cttcgccctc
     3901 tttgcaggaa ctgcggtcaa tgatacttcc tctgtaaccg ccacagctag cgcttgggac
     3961 agtctctacc agaccaatac cctcgaatcc gcaaccattg tcaaactcac gcgcacccta
     4021 gctatcatcc ccatcactct ctttctctcc tactggcaaa gtcgcgagca aaaaaataag
     4081 caaggcttac aactgaaaaa agtcttccca ctttttatcc ttcacttcat ccttgcatcg
     4141 ctcctaacca cccttctgac ctctctcggt gtgtctagta gtttctttac ccctctcaaa
     4201 caactctcta aattcctcat tatcatggcc atgagtgcca tcggtctcaa aactaatctg
     4261 gtcgctatgg tcaaatccag tggaaaatcc attgttctcg gagccgtctg ctggattgcc
     4321 atcatcctca ccagccttgg tatgcagacc cttatcggca ttttctaata ctcttcgaaa
     4381 atctcttcaa accacgtcaa cgtcgccttg ccgtatatat gttactgact tcgtcagttc
     4441 tatctgcaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct acaacctcaa
     4501 aacagtgttt tgagcagccc gcggctagtt tcctagtttg ctctttgatt ttcattgagt
     4561 ataacacaaa aggtagccca tcagctacct ttttcttatg cttcctcaat caagcgagta
     4621 tgttctctct tgatacagcg attcatcacg atatcatcac atccaccatc acgcaaaatc
     4681 tctttcgctt ctaaactttc aagtcctagc tgtgcccaaa aaatcttggc atcagctttg
     4741 agaaaatcac gcgccacatc gggcagaaat tcactgcgac gataaacatt gacaatatct
     4801 acaggaaaag gaatttcagc gaggctagca taagcctttt cacccaagat ttcgccacct
     4861 gccgccttgg gattgactgg gatgatttta tagccccgag cctgcatttc ctttgttact
     4921 cgattgctgg ttgtttcttc acggtcagac aaacccacca cagcaagggt tttactcgtt
     4981 gcgagatact gacgaatcac gccatcactt ggattgataa attcttgact catagaaatc
     5041 ctcctttttc atcagtatag cacattttga aaaggtttgc agaattctac tacaaaaaag
     5101 gaggactagc ccccttttta tttagcctcg taccaggttg ccccttcatt ctcatctgcg
     5161 ataagaggaa cactgagttg aatggcttct tccatggttt gtttcaccaa ttttttcatc
     5221 tctaccaatt cagatttagg cacttcaagg acgatttcat cgtgcacttg taacagcatc
     5281 ttagtctgat aaccacctgc aaccaaggct ttatccagct gaatcatggc aatcttgaga
     5341 atatctgctg ccgaaccctg gataggtgag ttgatagcag ttcgctccgc aaaaccacga
     5401 atattgaagt tgcgcgaatt gatatctggc aactcacggc gacgcttaaa gagggtctct
     5461 acatagccct tatcacgcgc ctcccgcacc acttcatcca tgtagttttt aatacctgga
     5521 aaacgttcaa agtaggtatc aatgtaggct ttggcttcct tacgactaat tcccaaatta
     5581 ttagacaagc caaagtctga aatcccataa accactccaa agttaactgc cttggcattg
     5641 cgacggtcat ttgcagtcac attatcagga cgctcaatgc caaagacccg catggctgtc
     5701 gaagtatgga tatctgcccc ctcttggaag gccttaatca agtgctcatc cttagaaata
     5761 tgcgccaaaa cgcgcaattc aatctgtgaa tagtcagagc tgagtagcac actatcctcc
     5821 cactctggca caaaagcctt ccgaatcaag cgcccttgtt ccaatcgggc aggaatattt
     5881 tgcaagtttg gatccacact agacaaacgc ccggtctggg tcaaatcctg caaatagcga
     5941 gtatgaatct ttccatcagc caaaatccag tcctgcaagc caattacata agtagattga
     6001 atcttagcaa tttgacggta atccaggatt ttcttaacaa tcggagcaat aggagcgaga
     6061 cgctccaaaa catccactgc tgtcgaataa cctgtcttgg ttttcttagt gtattctaga
     6121 ggaagtccca atttctcaaa gagaagcacg cccaactgct taggcgagtt gacattaaac
     6181 tcctcaccag ccagctcgta aatctcttga gtcagttttt caatgacaag ctcattttca
     6241 gcctgcatct caagcaaggt ctctttcttg accacaatcc cagcaatttc catcttggca
     6301 aggacaaaag ccagaggttg ctccatatca taaagaagct ctaattgccc attttcgctg
     6361 agtttttcaa gtaaaatagg ctctgtttct accaaaacag caagtttaca agctaagtgt
     6421 tccaagaatt tctcacgttc aggaatggcc tttttaacac ccttaccgta gaaagtttca
     6481 tcatcaacca agtaaggctg accataaaga ctagcgatgg tcgcaatttc attgtcctcc
     6541 acagtcgaaa ggaggtattt agccaaacgg atgtcaaaag caggcgcctg caaatccaca
     6601 ccaaaacgtt gcaaaagaac tttaaccttc ttaaagtcat aaactctcag agatgttttt
     6661 tctaagaaat ccttgaaaat cgggtcttgc aacagctcaa gcttgtctgt ggcatagagc
     6721 ttatcctcac aagaccaggc aaatccaacc aaattatccg tatggtaatt ctcaccaaaa
     6781 agctcaaagt ggaagataga ctcttcactc agcatatctt gactgatttg gtcaacaata
     6841 gtaaaatcca aacccttagc cacatcagct gacgacacat ttaaagcctg cttgagctgt
     6901 ttgaatccca tctcatcgta aaatttccca agattttcaa catctggacc actatagacc
     6961 aagtcctcta aaccaatcgc aatcggtgcc ttggtatcaa tggtcgctag tgttttagac
     7021 aaaaaggcct gttccttgtc attgatgaga ttttccttca tcttagaagt cttcattcca
     7081 tcaatatttt cataaatccc ctcaagcgaa ccatgctcca gcaagagctt aatacccgtc
     7141 ttttcaccga ctttggtcac cccagggata ttatccgact tatcacccat gagcgccttg
     7201 agatcgataa actgagctgg tgtgaggccc atttcttcca tgaggtaatc tggcgtaaag
     7261 gcctcaaact cagccacacc tttcttggaa atttcaacca ccgtatgctc atccgtcagc
     7321 tgaatcaaat ccttgtcccc actgacaatg gtaatatcaa aaccatcctg ctctgctagc
     7381 ttatccagcg tcccaatgat gtcatccgcc tcatactgag ccagctcata gtgacgaatc
     7441 cccatatgat ccagcaactc acgaatgaaa ggaaattgct cacgaaactc atcaggagtc
     7501 ttggcccgac cacccttata gtccgcatac atctctgtcc ggaaggtcgt ctttcccgca
     7561 tcaaaagcca ccaaaatatg actcggctca acccgctcca acaaatgact caacatcaac
     7621 tgaaaaccat aaatcgcatt ggtatgcaaa ccagccgcat tcttaaaacg gtccaactgc
     7681 tgatacagcg caaaaaacgc ccgaaaagct acagaagacc catcaatcaa taataatttt
     7741 ttcttatcca tacacccatt ataaaggaaa gaatcaaaaa ataccattgg gaagagctag
     7801 agcaagtatt tttcaaactt tttccgaata aatagataga gccaaagaat ttagtaaacc
     7861 tagatttaaa aatgtgctat aatatagtat attgaatcta taatagtaca ccttgactgc
     7921 taaaatattt ctataaatta atttgacttt cctgatagag ttattcacat cttatttcaa
     7981 ctcactatag aaggaggaat aggaggattc tcagacatcc gggcatcagc ccaactaatg
     8041 atttgattgc taagaaaata ttcagcaatc cagaaatcac ttgtcaattt attcgcgata
     8101 tgctggactt gccagcaaaa aatgtgacca ttttggaggg aagcgatatt cacgtattac
     8161 tctccatgcc ttactcggtg caggattttt ataccagtat agacgtcttg gcggagttgg
     8221 ataacggtac tcaagtaatt attgagattc aagtccatca tcagaatttt ttcatcaatc
     8281 acttgtgggc ttacctgtgc agtcaggtta atcaaaatct tgaaaaaatt cgtcagcgag
     8341 aaggtgatac tcactagagc tacaaacaca tcgctcctgt ttacgccatt gctatcgtgg
     8401 atagtaatta tttctcagat gacctggctt ttcatagctt tagtatgcgc gaagacacaa
     8461 caggtgaggt attggcgatt accaacaatg gacaggaaaa ccatctggtt aagatggcat
     8521 tcttggaatt aaaaaataca gagaaaccag caaagacaag gttcgcaagc catggttgga
     8581 gtttttcggc aacaagccct ttacccagca acctgagcga gccattaccc aagcaaatca
     8641 actgctggac tacaagagct ggtccgagga ggacaggaaa atgtttagtc aactatatat
     8701 gcgagaagaa caagtcttgt tagcacagga ctatgccttg gaaactgcta gggctgaagg
     8761 ccttgaacaa ggactagagc gtgggaaagt tgaaggaagg gcagaaagga aactttttgc
     8821 cttcctagac acagtacgcc aaggtcttct gacttctgag gttgccagcc agcaattagg
     8881 tatgtcagta tctgaatttg aggcactgtt gtaaaatggc tccataatat ccatagtggg
     8941 taaatcccct atggatatta tggagcctat tttgtgtaga aaaaaagtcc catatgacct
     9001 ataatgaaaa gcgaccaaac aactcattag aaagattcat atggaacaat tacattttat
     9061 cacaaaatta ctagacatta aagaccctaa tgtccagatt ttagacatca tcaataagga
     9121 tacacacaag gaaatcatcg ccaaactgga ctacgacgct ccatcttgcc ctgagtgcgg
     9181 aaaccaattg aagaaatatg attttcaaaa accttctaaa attccttatc ttgaaacgac
     9241 tggtatacct actagaattc tccttagaaa gcgtcgattc aagtgctatc actgttcaaa
     9301 aatgatggtc gctgaaactt ctgatgacgt acagtcatat ttcttctctt tttattatat
     9361 cacagtttta aatctagctt tactagattc accgctacta tctatttatt cggaaaaaag
     9421 acgaaaaaac ctgagaatca tctcaggctt ggtcattaaa tttttttctc aatatcgaaa
     9481 agtggagaaa gtggtcgttt ttcatgaata cgtacgatag catcccctag gagatgagcg
     9541 attgaaatct gctcaatctt atcaatcaaa cgctcttctg gcagatagat ggtatccaaa
     9601 acaaccaatt tcttaatagc tgatttttgg atattgtccg tagcaggacc agaaagaact
     9661 gggtgcgtac agcttgcata gacttcaaca gcaccagctt ccgcaagagc atctgccgca
     9721 tgacaaatcg ttccagcggt atcaatcata tcatcaatca agatacaagt cttgccttca
     9781 accttaccga tgatgttcat aacttcacta gtattcatct tatcaacgct acgacgttta
     9841 tcaataatag cgatagatgt tttcaaaaat tctgccaact tacgagcacg agtcacccct
     9901 ccatggtccg ggctgacaac cacatagtca gaaccaacca taccacgccg ctcaaaataa
     9961 tctgcaatta gaggagcacc catcaaatga tccacaggaa tatcaaagaa tccttgaatt
    10021 tgcgcagcat gcaagtcgat ggtcaataaa cgatccactc cagctacttc aagcatattt
    10081 gcgacaagtt ttgaagtgat tggctcacgc gctctcgcct ttctatcctg acgtgcatac
    10141 ccatagtaag gcatgacaac attgacagac tctgcactcg cacgcttcaa agcatctacc
    10201 ataatcaaaa tttcaagcag attgtcattt acaggcgaac tagttgattg taagataaag
    10261 acgtgtttcc cacggattga ttcttcaatg ttgacctgaa tctctccatc tgaaaattgg
    10321 cgaacacttg atttccccaa ctctatccca atctcctgcg ccacacgttc tgccaattct
    10381 ttattagaag aaagggcaaa cagctttaaa tcagaaaaag acatgatttc ctccggtata
    10441 tatgtataac ttgtgctttt cacaagattt tccatctacc attgtagcgc tttttgcact
    10501 atttttcaat caaaaataaa agaagggcac catatttgta cccttgcatc attcttttga
    10561 aaaatattct aggtcatcaa ctcattgtgt ttctcaacaa agcaataagc atgataaaaa
    10621 ccatagagag caatagccgt aaccactgga atcgctaaag gcaactctgt ttccaactcc
    10681 acaaaaggag agttaaacaa gaagtgagtt cccaaggcta aacctagaaa aataaggccc
    10741 tgtttcttgc caaccttctg tcctttatag gctctgtaaa gcaagtaaac acctactaca
    10801 gctagacctg aaaaagtcca gtgagaggca attcctgaga tgatacgctc taaaattcgc
    10861 gaaatagtaa agtcaaagcc ctctggcaaa tccgtacgaa tataaccaat atccttaatc
    10921 atttggaatc ccaaaccgga agcaattcca agtaaaaaca aagattttaa ttttcgcaca
    10981 ggaatcaaag ccaaaacaaa aacaagtggc aataatttca agggttcttc taccaaagga
    11041 gccacaatag cactttcaaa ggcatttaaa aatgtactat ctgggaaaag aacccccagt
    11101 aaatcatgga tataagtatt agcaaaacta gacaaccagc ctgaaaggaa catccctccc
    11161 aataaagaca gaatcaaaac cttctttggc aattcccatt tttcccaata cggaagagaa
    11221 aataaagagc cggaatcatg taaaagagag ctagaaagat agaaactccc attagtccat
    11281 attccgcacc tgacctcgaa ccgtccgtat agtagatggt ttcatactgt aaaccaatac
    11341 atagcaataa aataaaaata aataaaatac tgcttttctt catacacttt ctttctaaat
    11401 gaagtattta taattctacg actgtcatac ttcctgtatc aacattgtaa atggcaccag
    11461 agataatgac atcgtctggt attaggggag actcgataag cagttgcata tcctcgcgta
    11521 cactctcttc tatatcttgg aagggcaaga agtcctggtc tgacacatct acacctaatt
    11581 cctcttttaa atactcctga aaaggttcat tttcaaaggt ctgagcacca cagtctgtat
    11641 ggtgcaatac cacaatctct cttgtcccca tttgttgctg ggaaataact agcgaacgaa
    11701 tcatgtcttc agtcactcga ccacctgcat tccgcaagat atgagcatcc ccaagtgcca
    11761 agcccagagc ttgcgcaacg tgcagacgag agtccataca ggtcacaata gctactcttg
    11821 ttttgggttt aagtggcaga tttaactgcc catgtagggc aacataagcc tgattagctt
    11881 gcataaactg ttcaaaatac gacacgattc cctccttgaa aatttgatag tcaaatattt
    11941 ctcctatctt atcattttta agagaatttg tcacggatta tgcaaagacc tttttcaaaa
    12001 cttcctgaat cgttgtcacg ccaatgacct gaatttcctt aggcagagtg attcctgtca
    12061 aggaattctt aggtacataa atcttagtaa agcccagttt agcagcttcg ttgatgcgtt
    12121 gctcaatacg attcacgcgc cgaatctctc ctgtcaagcc cagttctccg acaaaacatt
    12181 cctgaggatt agttggcttg tctttgtagc tcgaagcaat agcaactgca acagccaagt
    12241 caatcgcagg ttcatccaat ttaacaccac cagcagattt gagataggca tcctgatttt
    12301 gcaagagaag ccctgcccgt ttttccaaaa cagccataat caagctagca cggttaaaat
    12361 caagtcctgt cgtagtacgc ttggcatttc caaacatggt cggtgttacc aaagcctgaa
    12421 cctccgccaa aatcggacgc gtcccttcca tggttacaac gatggaggaa ccagtcgccc
    12481 catccaaacg ctcttctagg aaaacttgac tcggattgag tacctcaacc aagccgcccg
    12541 actgcatctc aaaaatccca atctcattag tggaaccaaa acgatttttg accgctctca
    12601 agatacgaaa ggtatggtgg cgctcccctt caaagtaaag caccgtatcc accatatgct
    12661 ccaacatacg aggtccagcc aaggtaccct ccttggtcac atgacctacg ataaagatgg
    12721 cgatattatt tgtcttagcc aactgcatga gctcagccgt cacctcacgc acctgagaaa
    12781 cagacccctg cacccctgaa atctcaggag acataatggt ctgaatggag tcaataataa
    12841 ggaaatctgg ttggatgcgc tctacttctg cacgaacact ctgcatattg gtctctgcat
    12901 agaggtaaaa ctcgctatca atatcaccca agcgctctgc acggagttta atctgctggg
    12961 cagactcttc accactgaca taaagaaccg ttccaacttg agacagctgg gtagagactt
    13021 gtaggagaag ggttgatttt ccaatcccag gatccccacc gatgaggacg agacttcctg
    13081 gtaccactcc gcctccaagt acacggttga attcctccat ctccgtcttg gttcgattga
    13141 cattgattga agtcacctca gccagtttca tgggcttggt tttctcacct gtcaaggaca
    13201 cacgcgcatt cttgacctcg gcaacctcaa tctcttctac aaaagaagac caagacccac
    13261 agttggggca tcgtcccaga tatttagggg aattataccc acaattttga catacaaatg
    13321 tcgctttttt ctttgcgatg ataaacctct ttctatatct ctaactcaca ctcaatcact
    13381 tggcaaaaat caatcttctc atttggcaca aactggcgca tgagcattcg atgagcaaca
    13441 actaccacag tctgatgttc tcgatactta gacatacatt ctagaaaccg agacttcatt
    13501 tccgtagctg tctcatattg aataggacta ttaggaagta actcccccct gttttctaaa
    13561 aacagtcttc tagctgtttc aaagttttct attcctgttt tatagacctg ccattcatgt
    13621 aataaaggct ctactcttaa aggaagaccc gtagcacaga ccacatacga agccgtttct
    13681 aaagctcttg cgactgcaga agatacgatt atttcagctg acgagagtaa aggatttttg
    13741 ctcaatttct ggacttgctg ccgtcccata tcagacaagg gtgccaaatc tatcccaaat
    13801 cctatataag aacgctcctc taactcacgg taatctggct ccccatgacg tacaaagata
    13861 atcttcattc tagtgccctg tcgatccaaa tccaccagtt cgaacgccat cagccgcatc
    13921 tccatctgca attaagaaag tagcaaaaac agcctggaca atacgttccc caacttcaag
    13981 aacaacctct tggtctgtga tattcttcat ctgcgcaaaa atatgccctt catttccagg
    14041 atttccataa taatccccat caatgacccc aactgagtta attaaaacca agcccttctt
    14101 acgaggattt gaagaacgat catagaggta gagaacctca gtcggctgca tataagcctt
    14161 aacccctgtc ggaaccaaga caatctctcc tggcgcaaca actgtacgca cagcaacctt
    14221 taagtcgtaa ccagccgcat gcgctgtctc acgcttgggc aataaatttt catctgtaaa
    14281 actcgaaacc aattcaaaac cacgaatttt cataattttc tcttttctat tatcatttat
    14341 tctagattat tctatcttat ttattcggaa aaagcacgaa aaaaagagca cacaacaatt
    14401 ataggcgata cgataattta cactgtttca caatacgttg aaatttagag ctttaaagcg
    14461 agggcaaagt tgatttttta catcgtttta cagaggttta cgacactttt gccccttttt
    14521 tgcccctttt gagcaaacaa aaaaaccgca agcctgagcc tgcggtgaaa gaacaattta
    14581 gaaagtttcc tttctattta tttaactgta atcaagccat ctggctctac tgtgaactct
    14641 ggcttatctg ccagtgttcc gtctggtttg aggtagtacc agcctgttcc gtccgctgac
    14701 tggataaaag catttgatac catagcacct tctttagcgt ctaagtagta ccaagtgtcc
    14761 ttgtacttga cccaacctat ttgcatagca ccttctacat caaaatagta ccacttgtca
    14821 gcgattttct tccagcctgt ggccatttcg cctgattggt caaagtaata ccaattaccg
    14881 tctgtgtgct tcttccagcg gtctgcaagc atatagcctg agccatcgaa ataataccag
    14941 gtaccgttga ttttctcaaa cttatagaaa ggaggagata gtatggcaaa tactccaata
    15001 aaacctggaa cagataatca gaaacctggt cgctatgtag aggtaggacc tcgtggcgga
    15061 aaagttacta atggtcatac cgcaactatc ggaaaaggtg atcggctccc tccgacatct
    15121 gctaaaggca acggttggaa aaaagtctaa tcttcgtttg cgtacaatcg ttcaatggtt
    15181 gtacgctttt tccatacaca aaagcacatt cccaaaaaat caatttgaat ccatgcttcg
    15241 gcgtaatctt tcccattgct ggcatagtga gttatataat ggtgaatcat tttattcctt
    15301 cctcctattg agttacttga gaagtatcat gaatggcttc atagctaaga cgcttaaatt
    15361 cttctgagtc tatctgaaaa ttgataggct ttttttgtaa acactcaaga aaactagtgt
    15421 ttcttaaaag tttttcaact aactcagggt ctgcctttac aaaggtggac tctttttgtc
    15481 cactatacgg atatcgtttt ggtctcattt tcctactcct caaatctttc ctactcaatc
    15541 ccataatctt caataacctg aagaatgaaa ctgttcgctc gtggaccttt agtcgttcca
    15601 cttagaatgt ttgtcacttc ctgtcgttta aagccgtaag caaccgctag agttgctttt
    15661 ttaatgcctt tctctttcaa gaaagcaata actctttcgc gaccgtttgc gatatctggc
    15721 atattttctc ctttcttttt ctttcttctt tttctgctat aatataagca gaaaggagtt
    15781 aaccttatga cttttaaaga atatttactc aaagcaagca aacgcgacat ctacgatgat
    15841 ggtaaagatt ttgattttga aaccatcttt gctagagaaa tattacgtta tgcacacgat
    15901 tctgaactgg aaaccaaaac aggtttcttt cgtcatcttg aaatcatgaa tgctgattcg
    15961 tggtttgttg aacttgctcg ctcaatttat caagattttg agaaatcaat ttcagattct
    16021 cactaatcga gcgtgacttt tttgatatgg caatctcaga aatttaccac cagcgctgac
    16081 taccttaatg actttttcaa ggtggtcttt ttcttgttct aaatttttaa gaatacttac
    16141 catcagcacg ttcctcctct ttacttattt gtaaataaga aacaactaaa aatgtaacta
    16201 tttttctgca ttatacttga caacttacac caaatcggct aaaattaaag cataataaaa
    16261 acaccaataa atctataaat accgttcgcc aaaacatttt tataatttat ttcttagttg
    16321 tttttttagt tgtttatcac ttacaaaaaa cattttacac cttttgggat aattagtcaa
    16381 cctttttaca ccaaatttgt taaatttttt tgtgatgtct tagaaaggtt gatttaacaa
    16441 tgtttgagac atttgaaaaa ataaaagaat tggcaaaaaa gcgtggaaaa gctcttggac
    16501 aagtagaaga agacttaggt tatggtagaa atacactcta taagataaaa aattctacgc
    16561 caaacgctga acgtatcgca gaaattgcta attatttcaa cgtatccacc gactacctgc
    16621 tcggacgaac agataaccct gctatcgctg ggagtgatga atttgcccaa gtaaacggac
    16681 aaatcataga cttacgcaaa gcagcagcca acaccatgtt atttgacggg aaaccactaa
    16741 atgaagatga tatcgacttc attacatccg tcctatccgc ccacttcaaa agcaaaggag
    16801 aacgctaatg actatcacta tcaacttcac agaaaaaaat tcctacatta cggactacct
    16861 aaacaaacac ggtatcgaca caacgaccat ggattttgac gacttcatgg cactcatgga
    16921 agatatcgaa gacgcacgag cagccgacca agcctatatg gagtatttag ccgacccagc
    16981 tacttatacc atggatgagg tcttggatga actaggacta actcgagagg atattgctta
    17041 atgtatcggc tagatattga taaaaaagct ctcaagcaac ttaaaaaact agatacccca
    17101 accagaaaac aaatcctatc ctggcttgct aaaaacattg aaaacacgac caatccacga
    17161 caacacggaa aagcactaaa agccaacctt gcaggttact ggcgatacag agtagagaat
    17221 taccgcatca tctgtgatat ccaagacgat aaactagtcg tcctagccgt ggaaatcgcc
    17281 caccgcagag atgtctataa ataacgaagg agaactatga cactcgctaa actctgcgaa
    17341 gaatatcaag tagaactttg tctcttcgac ggttcaaact ggcacaatag cggtttctac
    17401 aatccagaca caaacgtgct cgctattgac cacaacttga ctcctgaaca acaaatccaa
    17461 gtcgccctac acgaacttgg acacaaagac cacacacgct cagagcacca gaacgcccgt
    17521 ctacgctgtg aaaacgaagc tgataggaat atgatccatc atctcgtaaa agacgctcta
    17581 gaaaacttag acgaccccac agagtttgat tacctcaaat tcatgtctta ctacaatcta
    17641 aaaaccatga caaatgaaat catggttaaa gaagagtatt tagcattagt aaattaaaaa
    17701 aaggagtatc aatatggaaa ttgataaagt aaaagccgat ttaaaacaag tcggcaaacg
    17761 tgtagcagac ctcagccaaa gcattacgaa tgaagaacaa acaaagaatg ccttcattat
    17821 gccgttcttc caagcgcttg gatatgatat cttcaatcca cttgaatttg tcccggaatt
    17881 tactgccgac gtgggcatta aaaaaggcga aaaagtcgac tatgcgatca ttttggatgg
    17941 cgagcctcaa atcctaattg aatgtaaatc aattacagaa aaccttacta agcacgactc
    18001 tcaactattc agatatttcg taactactaa atcaaaattc ggtatcttga caaatggtag
    18061 agaatataaa ttctttactg atttagatga gccaaataaa atggacacaa ctccattctt
    18121 aacaatcgat gtgactgata tcaaagaaaa tcaatttact gaaatcatca aattccacaa
    18181 agagaatttt gatattgata atattgtttc atcagcttct gaattgaaat acctcaacaa
    18241 tcttaaagcg ttccttactg aaaatatcac tacaccgtca gatagcttcc tcagatatct
    18301 aacttctgaa atctatgaag ggcgtgttac tcaaaatatc ttaacgacat tttctcccat
    18361 tattgtgaaa gggtttaatc aattcatcac agagcgagtt aatgaaaaat taagtgctgc
    18421 acttaataca agcgttgaaa ccaaagtaac aaccgatatt ccaaaagttg aagctgaagc
    18481 tgaagagatt gtcgaagtaa ctgacgaaat tatcacaact cctgctgaat tagaagttta
    18541 tactgttgtt aaaatgcttg ctagggatgt agtttctcca gaacgtgtat tttacagaga
    18601 taaccgtagc tatttcaatg ttttggttga cgataacatc aaaaaatggg tattacgtta
    18661 tcgttcaaat tcaaaaaaaa gcactatcga aatccgtgat aaaggcatct tcccggtgtc
    18721 tacccctctc gaagtcgcaa attatgccaa tgaaatttta gaagtaatca agaaattctc
    18781 ataataaaaa aagccctctt tactataccc attttatcaa aaaagtgagg taaaatcaat
    18841 gtggatggaa gaattgccaa acggcaaata taaatttttt gagagataca aagatccata
    18901 tactgagaaa ttaaaaaaag tctcagtaac gatggagaaa aaaactcccc aagcaagaaa
    18961 tcaagctgcg attttacttc aggaaaagat aaaacaaaag ttaggagaaa aacaacattc
    19021 tgtttctaat ataacttttg aaaaactata tgaagaattt gaggagaatt ggaaacacgg
    19081 cgtaaaaaac tcaaccgtct acgcttcaaa gaatgtaaaa aaagagattt taaagcagat
    19141 agagggcgac tacctagtta gaaatattga tagacgttta ttacaaaaag taatagatca
    19201 actattacaa gatgggagat ctcataacta tgtttctaaa atcaaattca agctcaatca
    19261 gataatgaaa tttgctatca gaatgaatta tattgataca aatgaaatgc tatttgttga
    19321 aacgcctaga aaagtaatta catccgacga actcaaaaag aaaaatacaa aatacttaga
    19381 ccaaaaagag tttaagttat tcatccaaaa tttaaaagac gaggccctat gtgattatcg
    19441 aattacaaag tatatccgaa tagctaaagt tctttttctt actggcatga ggtatggaga
    19501 gctggcagcc ttaaactaca aggaagatat agatttttct aaaaagacta ttcacatcaa
    19561 gcatacatac gatttcagac aaaaagagag aactacacca aagacaatca agtccgatag
    19621 ggttataaca gcacctcaaa aagtgttaga tattatcaaa gagcaaataa tagagaatgc
    19681 gacaaatgga tttgatacag attttatttt catcaatact ctaggagaac caataacaaa
    19741 tgccagggtt atttgtgcat tgaaaagaca tggtcaaaaa atcggcatag aaaaaaacat
    19801 aactacacat acatttagac attctcacat atccctactt gctgagctgg gcattccctt
    19861 gactgccatc atggacagag tagggcatag tgactcaaag accacactag agatttattc
    19921 tcacgttact caaaaaatgg tatcagacat atctagcaag ttagacaaga taaaatttta
    19981 aattgtgccc ctcgtctgcc cctttttctt atacaagaca aacaaaaacc ccttaaagtg
    20041 ttgattttaa agggttttta aagtgcacga aaaaagagca cacaattcaa atcgcttagg
    20101 gctgctggat tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata
    20161 tcacattcct attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc
    20221 tgcatgatag ctgcgcattc atcttccaaa attcctattt caacctccac acgatgattg
    20281 agacgctcat ctgtcaagat attgtacaaa ctcccagcag cgccaaattt ctggttttta
    20341 gccccataga ccacatttgg aatgcgggca agcccaatcg ctccactaca catgacacaa
    20401 ggttcaatgg tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc
    20461 gcatcctcta tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca
    20521 ttatgcccac gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca
    20581 tcgtgttcaa gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct
    20641 tcaagcgtat aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat
    20701 gaatcccaac acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa
    20761 aagaaaagtt taggatattt gttacaacaa gttaggaggt cttcttgtaa ccgtctatag
    20821 tatacccgac ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa
    20881 tatttgtttg ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt
    20941 cactcacacg acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgaactc
    21001 cggtaatatc ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt
    21061 gctcaagact agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaga
    21121 ttttcacagt atccaaaccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac
    21181 cagaaacacg acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac
    21241 gaccagttgt tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa
    21301 acaactcagt tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta
    21361 caaccttgtc aatcttgctt ggaccgacac cagaaccaat tgtcacacca ccagctacag
    21421 ggtttgatga cgtaacaaat ggataagtac cttggtcgat atctagcata acaccttgtg
    21481 caccttcaaa aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat
    21541 ctatcacgta tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga
    21601 aaacaatcgc tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac
    21661 gttctaaacg ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac
    21721 gagcagcctt gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt
    21781 cgcccttagc ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg
    21841 cacgatcaga aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact
    21901 cttttacaag agatttagga tttacaacca taccattccc aatgacagat attttttcag
    21961 ggaagaaaat cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg
    22021 tgtgaccagc attatcacca ccttggtaac gtgcaatcac ttctgcattc gctgaaagga
    22081 agtctgtaat cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag
    22141 tcataatctt gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac
    22201 ctgcaattat atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca
    22261 atagaaagat ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt
    22321 actatcatct ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca
    22381 agaaataaaa ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata
    22441 atggtaaacg ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa
    22501 aaatttaaaa tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc
    22561 ttcaatacta tcatagaaat tagccatctg ctcataaatt ttttgtaaca taatcaaata
    22621 ctccttttct tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc
    22681 ctgaattgtt aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa
    22741 acaaatttgc tacctaaatt tcaaacaatt aaagttctaa aaagaccgcc ttaaaacttt
    22801 tgggtaaatc ctaggtatta tggttctgat tttctagtat aaaaaaattc aaactagaat
    22861 tcttcttaga aaaggccgtt ttaagtgcta tcattgctca aaaatggagc tcgctgagac
    22921 ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc aaccaaaaga ttgctcagaa
    22981 gctaattgaa aagacttcta ttaccgacat tgatcatcag ttgtctattt caacttcaac
    23041 tgtcattcgc aagatcaata attttcactt tgagcatgat ttttcgcgtc ttcctgagat
    23101 tatgtcctag gacgttgaaa cagtccgggg agtgactgtt tcaatcggga gatggagatg
    23161 agctttattg ctcaggactt tgataaactc aatatcataa ctgttcttga gagcagaaca
    23221 caagccatca tccgaaatcc catgaataca aggctatcaa gcgctactgg aagctcattc
    23281 aacaagatag tcagaaactg agtgataaac gattttatcg ccctactttt cgtatgcact
    23341 tgactaataa agaaattcta gataaacttt tgagctattc cgaagacttg aaacaccact
    23401 ataatctcta tcagctctta cttttccacc tctttttcag actttgttta aaaccttcct
    23461 caaagataaa gagaaaatcg tcaacgccct tcaattacct tattccaacg ccaaactgga
    23521 agccaccaat aatctcatca aacttatcaa gtacaatgcc tttggtttta ggaactttga
    23581 aaacttcaaa aaagaaagga cgaaatttgt cctttctaga tcttcgcttt cttcaaccca
    23641 ctacagttga caaagaaccg aaaaatgtct cgcctctaat atagtcaatt gaaacaagaa
    23701 caagacaaaa gagcttcata aaaggtattg caacttggta ataccttttt gaggtgcttt
    23761 ttgatatgag cccatgtttt ctcaatagaa ttgtactcag gtgagtaggg aggaagaggt
    23821 aaaagtttat gcccaaactc ttcacacaag agtgctagct tacccattct atggaatctt
    23881 gcattgtcca taatatagta gattgaaact agaatagtac acctctactt ctaaaacatt
    23941 gttagaattc gattttactg ttctaatcga tttgtcctat tcttatttca ttttactata
    24001 acacgaaata gattattatt acataacaaa aaagaggtct aaacctctta actaaattac
    24061 tccgccagta ggactcgaac ctacgacatc atgattaaca gtcatgcgct actaccaact
    24121 gagctatggc ggatta
//
LOCUS       DBEJJE010000032        23998 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEJJE010000032 DBEJJE010000000
VERSION     DBEJJE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.32"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..681
                     /locus_tag="ACL3F5_001338"
     CDS             <1..681
                     /locus_tag="ACL3F5_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGR0515127.1"
                     /translation="APKPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNAN
                     GAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWYYLNTNGAMATGWLEYNGSWYYLN
                     ANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYY
                     LNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYYVNGLGALAVNTTVDGYT
                     VNENGEWV"
     gene            1081..2202
                     /gene="mnmA"
                     /locus_tag="ACL3F5_001339"
     CDS             1081..2202
                     /gene="mnmA"
                     /locus_tag="ACL3F5_001339"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0515128.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTTLLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2343..2798
                     /locus_tag="ACL3F5_001340"
     CDS             2343..2798
                     /locus_tag="ACL3F5_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0515129.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGFSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKFEDIQLVPAFLKTALPDWEGQLRHIHREE"
     gene            2808..4721
                     /gene="mnmG"
                     /locus_tag="ACL3F5_001341"
     CDS             2808..4721
                     /gene="mnmG"
                     /locus_tag="ACL3F5_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0515130.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDKILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDAVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(5055..6734)
                     /locus_tag="ACL3F5_001342"
     CDS             complement(5055..6734)
                     /locus_tag="ACL3F5_001342"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0515131.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6736..6969)
                     /locus_tag="ACL3F5_001343"
     CDS             complement(6736..6969)
                     /locus_tag="ACL3F5_001343"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0515132.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7249..7464
                     /locus_tag="ACL3F5_001344"
                     /pseudo
     CDS             7249..7464
                     /locus_tag="ACL3F5_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7788..7940)
                     /gene="cibB"
                     /locus_tag="ACL3F5_001345"
     CDS             complement(7788..7940)
                     /gene="cibB"
                     /locus_tag="ACL3F5_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0515133.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7942..8127)
                     /gene="cibA"
                     /locus_tag="ACL3F5_001346"
     CDS             complement(7942..8127)
                     /gene="cibA"
                     /locus_tag="ACL3F5_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0515134.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8305..8988
                     /gene="tsaB"
                     /locus_tag="ACL3F5_001347"
     CDS             8305..8988
                     /gene="tsaB"
                     /locus_tag="ACL3F5_001347"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0515135.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8985..9422
                     /gene="rimI"
                     /locus_tag="ACL3F5_001348"
     CDS             8985..9422
                     /gene="rimI"
                     /locus_tag="ACL3F5_001348"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0515136.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9412..10422
                     /gene="tsaD"
                     /locus_tag="ACL3F5_001349"
     CDS             9412..10422
                     /gene="tsaD"
                     /locus_tag="ACL3F5_001349"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0515137.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10462..11755)
                     /locus_tag="ACL3F5_001350"
                     /pseudo
     CDS             complement(10462..11755)
                     /locus_tag="ACL3F5_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12091..12782)
                     /locus_tag="ACL3F5_001351"
                     /pseudo
     CDS             complement(12091..12782)
                     /locus_tag="ACL3F5_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13025..14230
                     /locus_tag="ACL3F5_001352"
     CDS             13025..14230
                     /locus_tag="ACL3F5_001352"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0515138.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKQQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPYDTEGIPMCVLESMSQGTPVLANNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            14223..15098
                     /locus_tag="ACL3F5_001353"
     CDS             14223..15098
                     /locus_tag="ACL3F5_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0515139.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
     gene            15185..16801
                     /locus_tag="ACL3F5_001354"
     CDS             15185..16801
                     /locus_tag="ACL3F5_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515140.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            17061..17489
                     /locus_tag="ACL3F5_001355"
     CDS             17061..17489
                     /locus_tag="ACL3F5_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515141.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQILVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17501..18250
                     /locus_tag="ACL3F5_001356"
     CDS             17501..18250
                     /locus_tag="ACL3F5_001356"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0515142.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECIYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKIYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            18263..19435
                     /locus_tag="ACL3F5_001357"
     CDS             18263..19435
                     /locus_tag="ACL3F5_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0515143.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GNETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLYPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19831..20694
                     /locus_tag="ACL3F5_001358"
     CDS             19831..20694
                     /locus_tag="ACL3F5_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0515144.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20980..21213
                     /locus_tag="ACL3F5_001359"
     CDS             20980..21213
                     /locus_tag="ACL3F5_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515145.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            21235..21912
                     /locus_tag="ACL3F5_001360"
     CDS             21235..21912
                     /locus_tag="ACL3F5_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0515146.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21925..22590
                     /locus_tag="ACL3F5_001361"
     CDS             21925..22590
                     /locus_tag="ACL3F5_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0515147.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22662..23888
                     /locus_tag="ACL3F5_001362"
     CDS             22662..23888
                     /locus_tag="ACL3F5_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0515148.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7330 a         4062 c         5119 g         7487 t
ORIGIN      
        1 gctcctaaac cagaaactcc aaaaacaggc tggaaacaag aaaatggtat gtggtacttc
       61 tacaatacgg atggttcaat ggcaacaggc tggctacaaa ataatggctc atggtactac
      121 ctcaacgcta atggtgctat ggcaacaggt tgggctaaag tcaacggctt atggtattac
      181 ctcaacagca atggcgctat ggcgacagga tggctccaat acaatgattc atggtactac
      241 ctcaatacta atggtgctat ggcgacaggt tggctagaat acaatggttc atggtactac
      301 ctcaacgcta atggtgctat ggcgacaggt tggctagaat acaatggctc atggtactac
      361 ctcaacagca atggcgctat ggcgacaggt tggctccaat acaatggttc atggtactat
      421 ctaaacgcta acggcgctat ggcaacaggt tgggctaaag tcaacggttc atggtactac
      481 ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac ctggtactat
      541 cttgaagcat caggtgctat gaaagcaaac caatggttca aagtatcaga taaatggtac
      601 tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagacggata tactgtcaat
      661 gaaaacggtg aatgggttta agccgattaa attaaatcat gttaagaaca tttgacattt
      721 taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt ctttaggtac
      781 ctgtcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct aacttggaaa
      841 atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa gataagaaga
      901 aggtatactc acatcattca caaatctgta tattgactat aagttttaaa aaacaatttt
      961 taagctcttc cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct
     1021 tcaatcgtga agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc
     1081 atgagtgata actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg
     1141 gtgacgactc ttcttctcaa ggagcagggc tacgatgtga tcggtatctt catgaagaac
     1201 tgggatgaca cagatgaaaa cggcgtctgt acggcgaccg aagattacaa ggatgtggtt
     1261 gcggtggcag accagattgg cattccctac tactctgtca attttgaaaa agagtactgg
     1321 gaccgcgttt ttgagtattt cctagcggaa taccgtgcgg gacgcacgcc aaatccggac
     1381 gttatgtgca acaaggaaat caagttcaag gcctttttgg actatgctat gaccttgggg
     1441 gcagactatg tagcgactgg gcattatgct cgagtggtgc gtgatgagga tggcactgtt
     1501 cacatgcttc gtggcgtgga caatggcaag gaccagacct atttcctcag ccaactttcg
     1561 caagaacaac ttcaaaaaac catgttccca ctaggacatt tgaaaaagcc tgaagttcga
     1621 aaactagcag aagaagcagg tctttcgact gctaagaaga aagactcgac agggatttgc
     1681 tttatcggag aaaagaactt taaaaacttc ctcagcaact acctgccagc tcagcctggt
     1741 cgcatgatga ctgtggatgg tcgcgatatg ggcgagcatg caggtcttat gtactatacg
     1801 attggtcagc gtggcgggct tggtatcggt ggacaacacg gtggtgacaa cgcgccgtgg
     1861 ttcgttgtcg gaaaagacct gagcaagaat attctctatg taggccaagg tttctaccat
     1921 gattcgctca tgtcaactag cctagaggct agccaagtcc actttactcg tgatatgccc
     1981 gaggagttta cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg
     2041 accgtccatg tcaaaggaga caaggcagaa gttatctttg cggaaccaca acgcgcgatt
     2101 acaccaggac aggcagttgt cttttacgat ggcgaagagt gtctaggtgg cggtttgatt
     2161 gacaatgctt accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa
     2221 tttgctacaa taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt
     2281 ttttgtcctg cacttctttg gagttttgac tgtttttgtg tcgtttaagg gaaaggacaa
     2341 gaatgactca acaagacttt cggacaaaag tagacaatac ggtttttggt gttcgggcga
     2401 cagctttgat tcttcaaaat cgcaagcttc tagtcaccaa agacaagggc aagtattaca
     2461 ctatcggcgg tgcgattcaa gttaacgaaa aaacggaaga cgcggtagtc cgtgaagtga
     2521 aggaagaact gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt
     2581 ttgaacagga cggtttttcc tatcacaata tcgaatttca ttatctggtg gacttgctgg
     2641 aggatgcccc attgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact
     2701 tggataagtt tgaggatatc cagctagttc cagccttttt aaaaacggcc ctaccagatt
     2761 gggaaggcca actaagacac attcatcgtg aggaatagga gagaaacatg acttatcatt
     2821 ttactgaaga atacgatatt attgtaattg gtgcgggaca cgctggggtt gaggcttcct
     2881 tggccgctag ccgtatgggc tgtaaggttc tacttgcgac catcaatatt gaaatgctgg
     2941 ctttcatgcc ttgtaatccc tctatcggtg gttctgctaa ggggattgtc gtacgtgaag
     3001 tcgatgccct cggtggcgag atggccaaga ccattgacaa gacttacatc cagatgaaga
     3061 tgctcaacac agggaagggt cctgctgttc gtgcccttcg tgcgcaggct gacaaggaac
     3121 tttactctaa ggagatgcgc aagacagttg aaaatcaaga aaatctgacc cttcgtcaaa
     3181 ccatgattga taagattttg gtggaagatg gcaaggttgt cggtgttcgt acagcgactc
     3241 atcaagagta tgctgctaag gctgttattg tgacgacagg gactgctctc cgtggggaaa
     3301 ttatcatcgg agacctcaag tactcatcag gtcctaacca cagcttggct tctattaacc
     3361 tagctgacaa tctcaaggaa ctgggtctcg aaatcggtcg tttcaagaca ggaacccctc
     3421 cacgtgtcaa ggcctcttct atcaactacg acgtgacaga aatccaacca ggagacgcag
     3481 tacctaatca tttctcatac acttcacgtg atgaggatta tgtcaaagat caagtgccat
     3541 gctggttgac ctataccaat ggtaccagtc atgagattat tcaaaacaac ctccaccgtg
     3601 cgcctatgtt tacaggtgtg gtcaagggag tggggcctcg ttactgtccg tcgattgaag
     3661 acaagattgt gcgctttgcg gacaaggaac gtcaccaact cttccttgag ccagaagggc
     3721 gcaatactga ggaagtctat gttcaaggac tttcaaccag tctgcctgag gatgtccagc
     3781 gtgacttggt tcattccatc aaaggtttgg aaaatgcaga gatgatgcgg acaggttatg
     3841 ctattgagta tgatatggtc ttgcctcatc agttgcgtgc gactttggaa accaagaaaa
     3901 tctcaggtct cttcactgct ggtcagacaa atggaacgtc aggttacgaa gaggcagcag
     3961 gccaagggat tatcgcaggt atcaatgcgg ctctaaaaat ccaaggcaag cctgaattga
     4021 ttctaaaacg aagtgacggt tatatcgggg tgatgatcga cgacttggtg accaagggaa
     4081 ccattgaacc ttaccgtctc ttgaccagtc gtgctgaata tcgtctcatt cttcgccatg
     4141 acaatgctga tatgcgcttg actgagatgg gccgtgagat tggccttgtg gacgatgaac
     4201 gctgggctcg ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa cgcctagaca
     4261 gtatcaaact caagccagtc aaggaaacca atgctaaggt tgaggaaatg ggcttcaagc
     4321 cgttgacaga tgcggtgaca gccaaggaat tccttcgccg tccagaagtt tcttaccaag
     4381 atgtggtggc cttcatcgga ccagctgcag aggaattaga tgacaagatt atcgaattga
     4441 ttgaaacaga aatcaagtac gaaggctata tttccaaagc catggatcag gttgccaaga
     4501 tgaaacgtat ggaagaaaaa cgcattccag ccaatatcga ctgggatgac atcgattcta
     4561 ttgcgacgga agctcgtcag aagttcaaac tcatcaatcc agaaaccatc ggccaagcca
     4621 gccgtatttc gggagtaaac ccagcagata tttctatttt gatggtgtat ctggaaggta
     4681 aaaatcgtag tatttctaaa actcttcaaa aatcaaaatg atacgtcgta ggcttcttac
     4741 gaatgagttc aaagcttggc tttgattcat ctccaacctc ccatagttcc ccgaactatg
     4801 ggagctaact caagttatgc attttcctag ccttctggtc tgattttcat tgagttttaa
     4861 tctaaaaaga aagcatagag aaaaacagct ccgaggacgg ggctgttttg ttgatttgta
     4921 ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt
     4981 tgaggttgtg gatagaactg acgaagtcag taacatatat acggcaaggc gaagctgacg
     5041 tggtttgaag agtattattc ttcatctggt gtgaggatca tcgggatgat gatcggttca
     5101 cgttcggtat tttcatagag gaaggggcga atagcgttga caatggcacc attgacagat
     5161 tgcacgctag catccttatt tttcagtgcg atacgaatgg cattgaagag gatacgctgg
     5221 ctttgacgaa tcaagtcgcc agactctctc atgtagacaa agcctcggct gaggatgtct
     5281 ggaccagata gaatcatctg cgatttgaag tcaacagttg cgactgccag aacgacaccg
     5341 tcttcagata gatcgcgacg atctttgagg acagctgcgc caatttcacc gatacgattt
     5401 ccatcgacat agatatcttg ggcgttgaaa tggcctgcga tacgagctga gtcagcagta
     5461 agggcaagca catcgccatt gctcatgata aagatattgt ccttctcaac accagtatcc
     5521 actgctagtc cagcgtggac tttttgcatg cggtattcac cgtggacagg catgaagtat
     5581 tttggcttaa tcaagcagag catgagtttt tgctcttgct gaccaccgtg tccagatgta
     5641 tggatattgt tcactttacc gtggataact tcgacaccag cttcagaaat gatgttaatc
     5701 agcttgttga cgctagtagt gtttccaggg atgggactag aagagaagat aacggtatca
     5761 cctggttgta attgtacttg acggtgggtt ccgttggcga tacgagagag ggctgccata
     5821 ggctcaccct gactacctgt acagaggata agaacttctc ctgcaggata atctttgatt
     5881 tcatttggct cgataaaggt tcccttagga gctttgatgt agccaagatc gattccgttg
     5941 acaatggcct tttccataga acgaccaaag accgcaatct tgcgtccagt cttaacagca
     6001 gcttctgttg cctgctggag acggaagata tttgaggcaa aggatgcaaa gatgatacgt
     6061 ccttcaatac cttggataat cttcataatg gactgaccaa cgactttttc agagttggta
     6121 aaggttggta cttccgcatt tgtcgagtca gacaggagac agagcacgcc ttcttcacca
     6181 agcgcagcca tacgatgcaa gtccgcaggt tctccaactg gagtaaagtc gaacttaaag
     6241 tcacccgtac agacgatttt cccttgagga gtatgaatga caatccccaa aggctctgga
     6301 atagagtgag tcgttctaaa gaaagttgcc ttgagatttt taaaggtcaa ctcggtgttg
     6361 tggttgattt cgtaaagttt ggcgttgcgc aagaggccgt gttcttcgag tttcccacgg
     6421 atcaaagcca aggcaagcgg tccagcataa atagggacat ttgcttgctt gagtaggaac
     6481 ggaatcccac caatgtggtc ctcgtgtccg tgtgtgatta aaacagcctt gacgcggtcg
     6541 atattgtcta cgatgtaaga gtagtcagga atgacatagt cgataccaag caagtcatct
     6601 tctgggaatt taatcccagc atcgacgatg ataatctcgt cttggtattc aattccgtaa
     6661 gtgtttttcc cgatttctcc tagaccaccg atggcaaaaa caccaacttc ttcaggttta
     6721 agagtgtagg ccatattaga actccgtaat ttcgaaggcg ccagtttctt tttcgtaatc
     6781 gagcaatttg tcagacaaga gttcgatata ttcgatattg tactctgggc gattttcttc
     6841 gacaagttgg cgagcagtga tacggccctc aagttctgag ctggtatcga tgtctaggta
     6901 aagcgcgcgt gttgtttcac ggcgtgggct acgttctttt gtttcttgat aaaaaacttt
     6961 gtaaatcata tagttccttt ctatttacag gtcagcttat tccaaacttt tagcagatat
     7021 ttgcttgatt tcattccatt ttgtgtctag attgaccttg attcgttaca attatttcaa
     7081 ttataccaca aaatgaaaaa ttagtaaaag acggaaacga gaaagttagg ggacgatttc
     7141 tttggtaatc gtttgcaaaa ataaagaaaa tgtattatgt tgataacgga agtgaaattt
     7201 attgcttgtc ataattccat atagatttta agtcaaggag gttgccctat gtataactta
     7261 tttgcttttg ctatcggagt tcgtttgtta acttttatcg tttttgttgc ttgcgtttat
     7321 ggaggaaatc ttctatttgc caaactggaa cgatgacaaa ccaagttctt gtggaaaatg
     7381 acctttgtga ctctctactc gctttttctc ctccttgtaa cctatgtcgt ttggtttgta
     7441 ttttactttg gattaaatgc ttagatgccc tgctcatgct agggcatttt tgtttggaga
     7501 taagaagaca atagatttac gatacgaaaa gtccacccca tctatccaga tgaggcggtt
     7561 tttgtatttt ttagaaatga catgataatg gtattttcag agcttattag ttttatggta
     7621 atcattcttc tgatcaaaaa tagagttgaa gcataaaaat aaaacaatac aaacagataa
     7681 atcaattggt aaagggatag tagtaatgtt caaatcattg agaatgctga gcaaactgta
     7741 agagatgaag acaataaaat ttatccttat aaaaatatgt ttcttatcta gcatgactta
     7801 ccaaactttt tacgaaggtc ttttccaatg gtataacctg ccataaataa agcgatacca
     7861 acacctacac caaagccacc cttgatttct tgcaattcct tattagaaat ttcacgatag
     7921 ttgttcaaat ctttcatcat attaatctcc tcctaaaaaa taaccagctg ccaaaccaga
     7981 acctataagt gctgttccac ctgcaatagc cttccaagat actgctactc caaagataac
     8041 caagggagcg agaccgccat caatatctga taattcattt tcagataagg ataaaaattg
     8101 attgtcaaga atgtcaaaat ttgtcattga actttcctcc ttttttcttg ttcactttta
     8161 tattcggaaa agaaaaggaa aagtgagcat ttttttaaat tatttttagt taagtgaggg
     8221 cactcttgtc tgggggcaaa gaaaattccc atgtgccagc ttttgtagta taatagtaag
     8281 cagacaaaaa gataggaatg tgttatgaaa gtattagctt ttgatacgtc cagcaaggct
     8341 ctttctctgg ctattttaga ggataagcag gttcttgccg agacgacgat taatattaag
     8401 aaaaatcaca gtattactct tatgcctgcc atcgattttt tgatggcaag tttggattgg
     8461 acacccaagg atttggaccg aatcgtggta gctgaagggc cgggtagcta tacaggcttg
     8521 cgaattgcgg tagcaactgc taagacctta gcttacaccc tgaacatcga gttggttggt
     8581 atgtcgagtc tcttggctct ggtgccccac caacaagaag gtttgtttgt ccccttgatg
     8641 gatgcgcgtc gcaataatgt ttatgcagga ttttatgaaa atgctaaacc tgtcatggca
     8701 gaagcgcacc tatcttttga agaggtgcta gaaaaagtca agggtactag tcaggtaacc
     8761 tttgtcggag aagttggccc ctttgttgag cagattcaaa aacacttgcc aaggactgat
     8821 tacaaagaaa cattgcccaa tgcagctaat ctagctcttt tggcctggga caaggaagca
     8881 gactccttgc atgattttgt gccgaattac ctcaaacgag tcgaggctga ggaaaactgg
     8941 ctcaagaacc ataccgagtc tggtgagtcc tacattaaac gcctatgata gaaatcaagc
     9001 gaattcaaca acagcctgac ctagctcaag ccatctacgc tgttatagca gctgtttacc
     9061 tagtcagtcc ttggactctg gagcaaatcc aagcagatct gtcccaagac cagacttggt
     9121 atgcattggc ttatgatggg gcagaagtga ttggatttct agctgtgcag gagaatcttt
     9181 ttgaagcaga agtcctgcaa atcgctgtca aaggagccta tcagggtcag ggaattgcgt
     9241 cagccttgtt tgctcaattg ccgacagata aggagatttt cctcgaagtc agaaagtcaa
     9301 atcaacgagc gcaagcattt tacaagaaag aaaaaatggc ggtcatcgct gagcgaaagg
     9361 cctactacca tgacccagtc gaggacgcca ttatcatgaa gagagaaata gatgaaggat
     9421 agatatattt tagcatttga gacatcctgt gatgagacca gtgtcgccgt cttgaaaaac
     9481 gacgatgagc tcttgtccaa tgtcattgct agtcaaattg agagtcacaa acgttttggt
     9541 ggcgtagtgc ccgaagtagc cagtcgtcac catgtcgagg tcattacagc ctgtatcgag
     9601 gaggcattgg cagaagcagg gattaccgaa gaggacgtga cagctgttgc ggttacctac
     9661 ggaccaggct tggtcggagc cttgctagtt ggtttgtcag ctgccaaggc ctttgcttgg
     9721 gctcacggac ttccactgat tcctgttaat cacatggctg ggcacctcat ggcagctcag
     9781 agtgtggagc ctttggagtt tcccttgcta gccctcttgg tcagcggcgg acacacagag
     9841 ttggtttatg tttcggaggc aggagattat aagattgttg gggaaacccg tgatgatgcg
     9901 gttggtgagg cttatgataa ggtcggccgt gtcatgggct tgacctatcc tgcaggtcgt
     9961 gagattgacg agctggctca tcaggggcag gatatttatg atttcccccg tgccatgatt
    10021 aaggaagata atctggagtt ctccttctca ggtttgaaat ctgcctttat caatctttat
    10081 cacaatgccg agcaaaaggg agaaagcctg tctacagaag atttgtgtgc ttccttccaa
    10141 gcagcagtta tggacattct catggcaaaa accaagaagg ctttggagaa atatcctgtt
    10201 aaaaccctgg ttgtggcagg tggtgtggca gccaataaag gtctcagaga acgcctagca
    10261 gccgaaatca cagatgtcaa ggttatcatc ccccctctgc gactctgcgg agacaatgca
    10321 ggtatgattg cctatgccag cgtcagcgag tggaacaaag aaaacttcgc aggctgggac
    10381 ctcaatgcca aaccaagtct tgcctttgat accatggaat aaagagtggc tctttgtcaa
    10441 gtgtagtggg taggcgaaaa gctacaatct ggagagtacg aaattcgtac tctctttttt
    10501 gatgttcaaa gtcatcaaaa tccgtttttt aaaattgtta aagttccgga aaccaaaggc
    10561 tttgcgcttg ataatcttaa tcaaattatt ggtcgcttca agtttagcgt tggaataagg
    10621 cagcttaagt gcgttgataa tcttatctct atcccttaaa aaagtccaaa agaccgtttg
    10681 aaaaagcgga tgaaccgttg gcagttcttg ctcaatcaat ccaaagaaat ggtcggcatt
    10741 cttctcttga aaatgaaaga gcaggagttg atagagttcg tagtgaacct gtaatccctc
    10801 agagtaagaa agcagcttat ctcgtacttc ccgatgggtt aagtgcattc gaaacgtggg
    10861 ctgatagaat cgtttctgac agagcttgaa gctatactgg tgtagtaaat cagtccagtg
    10921 gactgattta gcccgagcct agaaacgaaa aagcgagggt tccaaaagcg cttgagcgcc
    10981 cgatactcca aggattttcg gtcaaattgg ttcatgattt ggattcgtac tcggttcata
    11041 gctcggctca gatgttggac aatgtggaag cggtcaagaa caatcttcgc ctttggaaag
    11101 agttgcttag cgagccgata ataagggctg tacatgtcca tggtgatgac ctcgaccagc
    11161 tcccgaacct ctctctgata gcgctggaaa tggtttcgaa tcaccgcatg agttcgcccg
    11221 tctaaaattg cgaggatgga tttggactca aaatcttggg caatgaagct cattttgctc
    11281 tttttgaagc tatactcatc ccaactcata acttttggca acttggtcca atcggtttca
    11341 aacttaaatt ccctcagttt tcggataacg gtggaagttg agaccgccaa tcagtcatag
    11401 actgcttttc aaggaggagc tgagcgattt tttgtctcac catgttggaa atctggcaat
    11461 ttttcttgac aatggatgtt tgagaaacga ccaccttaag gcaattcttg cactgaaagc
    11521 ggcgcttttt gagatgcagt accgtgggta aaccctgaca gtcgagaagc ggaattttag
    11581 aggctttctg gaagtcgtat ttgatcatct tcccttgaca atgaggacaa ggaggagcgg
    11641 gggaatccaa ctttgcctga acgactagat gggtttggta tttcagaaca gacaagattt
    11701 tgatattttt gtcttccaat ccgagcaaat ctgtggtatt cttaagttgt tccatatgaa
    11761 ccctttctaa tgagttggtt agacgctttt cattataggt catatggggc tttttttcta
    11821 caagaaacga ccctataatt cctggggtgg gattacccac tacagaaatt atagagccaa
    11881 agcattccaa agtcttgtct gactctggaa tgttttctgt tcacagttgt tttgtaactg
    11941 cctaataagt aaccgcgcta taacgaggta tctaccgaga ttgtcaattc tccagtatac
    12001 tgttataaaa aacaaaactg gaggattttt ttatgtcccc ccatcgtccc atcgactgtt
    12061 ccgtagctgc ccaataacgg agtatagtcg gctgaaacaa gaataggaca aaagtgcctc
    12121 aagaaaagca tcgtaatttg acaatattat tctgagatgt ttttgatgta agcccatatt
    12181 ttctcaatgg gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct
    12241 ccttacacat gttcattctg tgaaaccttg catggtccat aatgataagg gatggtgtat
    12301 ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat
    12361 ctttataggt catcggagcc atagtatatt gaaacaaaaa agggcattag tacttctata
    12421 acagtatcgc aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct
    12481 tccagagaga ctaactgcct gctcaaggct cgatcatatt cgagataaaa ataggtctca
    12541 acccctgtct cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg
    12601 aaccgattta ctttttctgg gtcttgttcg cagtaggtac ggctcttttt tagactatat
    12661 cccatagcct ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt
    12721 tcagtcaaat aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact
    12781 ttttcaatta atagtggaag ttttcttgaa gttagtgtat tgaaacgttt ttatacagtg
    12841 ctaaaatttg aagtgtagtg cagatgcatt tgtaatagta ttatagcaat tctttggaga
    12901 aggtcgagac aagataaaat aggtatcttt gagatataag catgatttac tataaaatta
    12961 ttgagttatt cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt
    13021 tacaatgcaa tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat
    13081 taaggatata gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg
    13141 tatagatccg catataattg gactttgtaa acagcagatc agaaggatgt ctctatatcc
    13201 tattttgata atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat
    13261 tgcctatgtt gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa
    13321 tattttaaaa ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt
    13381 tttatatatg ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac
    13441 atgccatgga tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg
    13501 gacatattct atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga
    13561 gagtataata aaaaataaga agatagttgc aataaataac ggaattaatg tatcaaatag
    13621 cgatttagat gtagtaggtg ttcaagactt taaaaaagaa ttttgtattc caaataacaa
    13681 aaaaatcatt tgttatgttg gaaggttgga tccagaaaaa aggccggata gattccttga
    13741 atttgcagaa aaattatttt tagtcagaga agatgtgatt tttattatgg ctggaaatgg
    13801 tagtatgtgg gctgctttga aagaaaaaat ttgccatttg aaatgtagag ataatttcag
    13861 gttacttggt gaaatctatc cagctactat agtttaccaa atatcggatt tattgtatat
    13921 tccttatgat acagaaggaa tacctatgtg tgttttagag tcaatgtcac aaggaactcc
    13981 ggttttagct aataatgttg gcgggttaag tgaaattatt gaacataggg ttgatggatt
    14041 tttatttgag aaggaagatg ttgagggagt gtgtgcttgt gctaattttt tactcaatga
    14101 ttctgagtat ttgaaatata taggtgagaa tagtaaatca aaaataagaa aacatttttc
    14161 tgtgcaaaaa atgtttgtag aaaccatgag agtatatgat gaattattag agaagagtag
    14221 tcatggatag gaatatagat caagaattag taagtattat aataccaaca cataataggt
    14281 atgaatctct gattagagct gtgaaaagtt gtttacatca aagttataaa aatatcgaag
    14341 ttataattat tgatgataat tatagtaatg taaatttaag aaataaaatt atccatcaat
    14401 ttggctatac caatcataga attaagttaa ttttaagtaa tgaagattta ggtgcaacta
    14461 atgccagaaa cataggtata aaaaattcta gaggtaagta tatatcattt ttagacgatg
    14521 atgatgaata tatgccagat cgaattttaa agttgatggc ttgttttaaa aagagtagaa
    14581 tgaagaattt agctttagtt tatagttatg gaataataat ttatccaaat ggtacacgag
    14641 aagaggagaa gaccgatttt gttggaaatc ccttgtttgt tcaaatggtt cacaatatag
    14701 caggtacgtc attttggttg tgtaaaaaag aggtgctaga attaattaat ggttttgaga
    14761 aaatagattc acatcaggac ggtgttgttt tattaaaact acttgctcaa ggataccaaa
    14821 ttgatatagt gcgagaattc ttggtgaatt actacgctca cagtaaagaa aacggtatca
    14881 ctggagtgac acaaaaaaca attaatgcag atgaagaata ttataattac tgtaggaaat
    14941 attttaattt attgagtttc aacgagagaa tattggttac aaagaaatat tattctttaa
    15001 acataaagcg gttactatta ataggagaca aatgcaaggc tttaaaagta atcaagaagg
    15061 caagagaaga aaaaattttt aacgaatttc ttttttgaaa tacatgttat tatattattt
    15121 tggttttttc tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac
    15181 tattgtgtat actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat
    15241 tgttgctggt caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga
    15301 attaattgcg atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg
    15361 gtgtgggata atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga
    15421 gtttaatcta gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga
    15481 atttcatagt aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt
    15541 aaatgatcag gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt
    15601 tgcagttgtg actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt
    15661 aatgattatg ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa
    15721 tttaactaac caaaatgaag cttttttaaa atctagtgag actatattga atggatttga
    15781 tgtgttagcg tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat
    15841 tttattaaag atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag
    15901 cttctttctc aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat
    15961 aaaaggaata gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt
    16021 tacagcgcta ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt
    16081 tttaaaattg tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa
    16141 tgaggtgaat agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga
    16201 taaagaaata ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt
    16261 aggtgaaagt ggaagcggga aatctacatt attaaaatta ttgagtggct ttttgagaga
    16321 ttatagtgga gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat
    16381 ggtttcgaat gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga
    16441 taatatttta ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt
    16501 tggtttgagt gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg
    16561 gagattactg tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa
    16621 taagaaaata gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc
    16681 gattgaacgt aagatattag atagagagga tttgactgtc attattgtta cccatgctcc
    16741 gcatccggaa cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta
    16801 agaatatagg ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag
    16861 agaaaaaagt atcatttttt tatgtagatg aaaaaccctt aaggtatctg ttatttgact
    16921 atatatttct actagttcta gctaaaaaaa atatcccaat cttatgaact gcaccccaaa
    16981 agttagattt attctgtcta acttttgggg tgcagttcat tttgcatagt tttggcattc
    17041 atcctagata tccatataaa atgtctgaga ttgttgaaat gtctaaaaaa atatcagatc
    17101 taaacgataa aaaagaattt cacaaaaaga actgtgagtt gaggtttcaa gatagtgttc
    17161 ttgataacat aaatagtgtc ccgggtacaa ctcatttatt tagttgttta aatattcaaa
    17221 tattagtaaa aattatttta tatatttttc gatacaacag ttgtatgaaa atatttaatt
    17281 ttagagataa agagcttatc ttttttaata agattgtaaa tgggctgata caaaatattg
    17341 aggagaattt agaggatgat attgaaagga tattgaaata tttatatata tgtttattta
    17401 acgaaatatt cattattaag aataaggtga atttttttga tgatgtggaa tttaatcaga
    17461 cacttagtga gtttttagat aaattgtaga gggaatggtt atgagtaaca atactaagta
    17521 tatcttttta tctccacatt tagatgacgc aattttttcc tgtggtgatt atatttcaaa
    17581 attaacttca gaaggagaaa ttgtacttgt tattactata ttttctggtt accctttgag
    17641 ccaacagcta cagccctctg ctaagcaatt tcataagttg tgtaaccttg ggaaatatcc
    17701 gattgaagaa aggaagaaag aagacaggtt agcttgtgaa cgtctacaat gtgattttag
    17761 acacttatcg tactatgaat gtatctatag gaaagataga aatggcaatt ttctataccg
    17821 tcatatctat agtgaattaa aaaatgagga cacattaaag aatgatatca taaaagagct
    17881 gttaatgcat ttagacgaca aatgtgtcgt atattgtccg ctttcacttg gtgaccatgt
    17941 tgatcatgtt tttgtgaata gtattggaag ggcgcttgaa tttatgcgtt ataaagtaat
    18001 atattatgag gatttcccat atgtaagtga tagtagtatg gttagttata tgggaaaaac
    18061 taaagaatta aaaatatatc aagaggaact tgatgaaaaa cattatattg atagaatatc
    18121 atcaatattg tgctataaat ctcagatttt gataatctgg aaatcagttg aaaaactttt
    18181 aaacaatatt aaagagttgt atttaaggaa tggggcagct tattctatta tattttggat
    18241 taagaaataa ggaagtagtt ttatgaatat agcagtaatt ggtttggggc atgttgggct
    18301 ggcctacgcg ttactatttg catctaaata taaagttgtt gcatatgata tagattctgt
    18361 aaaaataaat aatttaaaaa agggcattct tccatctaaa aatgaagagc ttatgaagtt
    18421 tttttgcgag aataacttaa atattacttt ttttgataca ttttctgaaa ttaaaaataa
    18481 tattgattat tatattattg cgcttccgac agattatgat gagaaaattg gtagttttaa
    18541 tacatatgaa atcgaacaaa cggtatcgaa gattctgagg gtaaaaccta atggaaagat
    18601 tattttaaag tcaacagttc cgatcggctt ttcaaacaaa ttaaaaaggc tgtttgatac
    18661 aaaaaatatc atttttgtcc ctgaattttt gagagaaggt tgttccatat atgataattt
    18721 atatccaagt cgcatagttg ttggaaatga gacagttgaa ggaagaaaaa ttgcagagtt
    18781 gttcctttcg attagtactc atagtactgc caatattaaa aatgttatgt tagtttctcc
    18841 tactgaagca gaagcaatta agcttttttc taacacattc ttagctctcc gtgttgcttt
    18901 ttttaatgaa ctagattctt ttgctgagag gagaagttta aatgctgaag ttgtaataaa
    18961 aggtgtttgt ttatatccaa gaattggaaa tttttataat aatccttctt ttggatttgg
    19021 aggatattgt cttcccaaag atactaaaca attaaaaaaa gaatttatag aaataaatgc
    19081 cccagtgata gaagcgattg atatttcaaa cacaaataga aaacagttca tagttaaaca
    19141 aatattggaa cgaaagccaa agatagtagg aatatataaa ttggggatga aatataattc
    19201 agataattac aaagagtcag ctattttaag tataattaat gaactattga ttgtcggtat
    19261 aaaaatttta gtatatgaac caaatttaaa cgttagtata gataacgtaa tttttgaaaa
    19321 gaattttgaa ctatttacaa aacaaagtga tctaattgtt gcaaatagat gggatagggg
    19381 ccttgaagct tataaagata aagtttacac aagggggatc tggataagag attaactatt
    19441 gatattaaaa aggcaataat ttataaaatt tgtacaaaaa aatgttaaat tttcacattt
    19501 tcatagtata ctgtttaata gaaagtaggt tctttgtaac cgctccatta taaaatcctt
    19561 tcactcttcc ggtatactat taggaaaaac ataactggag gatattttga gctcacacct
    19621 catcgttcca gtggctgttc cccaagctcg tgtactgccc aaaaaagtta gacattctat
    19681 ttagaacgag gattgagttc tgtattgtac aaggctcggt ccttttagag tcagcttaag
    19741 gctggctttt ttattttttc taactatcag aatattttga caaatgaaca caaataatga
    19801 tataatatgc aaaagctagg aggtggtagg atgattgaaa aaatggaact gggggaattt
    19861 tacaaggaat tacgtttggc gagaaagctc aagcagtcag atgtggcttg tgacgggcta
    19921 acagcttctc agttgtccaa gtttgagcta gggcagtcca tgttgtctgc tgataagctc
    19981 atattagcca tccaagggat caatgtgacc tttgatgagt ttgggcacaa gctcaacaac
    20041 tatcaagaat ctccacatat gcagattggt agaaaggttg tggatcgctt tgctcatcaa
    20101 gatatagctg gcttagagca actgttggag gaagtcgagc aagaacagat ggcgcagacc
    20161 tatcgtcgtt tgaatgccat cgtgattaaa gatgccatcc attcactaaa taaaagctac
    20221 ccactagcag aggaggatag cgagtttttg accacctatc tctatgctat cgagtcttgg
    20281 acctggtttg aactctatct cttttgcaat accatgccct tcttgagcaa tcaagatctg
    20341 atttttttat caacctcctt actcgaaaaa tccaaagaat ttaaagagtt agtacacaat
    20401 cgattgtata tgaagcaagg actcttaaat atcttatcag aactcatgga gcgaaaactt
    20461 ttctcctaca tcccaatctt cgaagccgag ttggagagga tgttacgacc gtatgatgtt
    20521 tttgaaaaag tatcgtggca atttttaaag aagatgagtg tctttcttca aacaaaggga
    20581 agcaatcaaa aagagattga acgctttatc caatctctgc aggtattaga aaatccacaa
    20641 ttaatagccc tttttgaatt gcgtttgcag caatacaaaa agcttatcga ttagttagaa
    20701 atggcaaaat aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca
    20761 tatttctcca ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc
    20821 aaaatcgcaa atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata
    20881 agccaatgtt cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga
    20941 agtggtttac aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca
    21001 gaaacaatgg aattgacaga agctgagttg caagatgtta gaggaggcaa cctcgtaaat
    21061 tctatgggag gtggtggaag aagtggtata tctggttggg gcgtcccagg aatttaccct
    21121 ggttggggca atcaagggat gagtcctaat cgtggagctt ttgattggac tatagattta
    21181 gcagatggat tgtttggccg ccgtagaaga taggctctta taggagataa taggatgaag
    21241 aaaatgaaag aagtgaaatt tcacctagca actggcttgt tgattttgac ttattacctc
    21301 atttttaatg tcacatcaga cttagatttt atggttgctt tgtctgataa tatgtactat
    21361 gtgttccaag ttttattggt acttattctg ggaactatag ctacaattgc ttttgtcaaa
    21421 agtgaacatt ggaaagagtg tggtcgtttc cagtttcgtt ggtcttacct gggtgttttc
    21481 cttctttctt ttttcttatt gttcgtgtgg gcaaatctaa caacctatat ctttcctcgt
    21541 acccagaatg gaagtacagt cgtagaagta gccaccaatt taacaggaat tagctatttt
    21601 gttacgcgaa tactttatac tagtattatc gcacctgtat cagaagaggt tgtttgtcgt
    21661 ggtcttttga tgacaagttt atctaaagtt aagagatact atcttgatgt tcttgtttcc
    21721 gctgccatat ttggcgctat gcatgttttg cagtatggtt ggataacgac agatttcata
    21781 aagtattttg gaatgggctt gatattttgt atgatgtttc gctacacccg atccatctat
    21841 tgggctatag ctctgcatgc ttcatggaat agtttcttac tcattgttac tttattggta
    21901 tttggatatt agaaaggtga taatatgaaa aagataatct cacaccgcta ctttattata
    21961 gtttttctac tagttattgc tgaccagaag ttcagtgttc tagttttacg cagcgacctt
    22021 gttactgggc tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg
    22081 gttttatttg ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga
    22141 aagtttaaag gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg
    22201 aattttgtca ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct
    22261 gctcctactt ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca
    22321 ggtcccattt ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga
    22381 aagaaatggg ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt
    22441 aatcacggtt gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca
    22501 gtcttattta gaatgacaaa gtcaatttat tggcctattg ggctgcatat agtctacaac
    22561 ggcattggtc agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt
    22621 tctggggaaa gattcccatt tgaacttaag aaggagttgt gatgaaagta tttcttcaaa
    22681 atagagattt taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt
    22741 tttatctggc ctttctgaat tatgtggcag atgcgtcttt tgcacctttg gcgattttac
    22801 tcattacgat ttcagaaacc cttccccaaa ttttacaaat ctttctggga gttttggcag
    22861 attttcaaca tcatcgtgtc ttgaaataca cagtcattag ttttgcaaaa tttttgcttt
    22921 actctatcgt ttctttatca ctttcagggc agtctttctc cttgttgcta gtagcattta
    22981 tttgtctgat taacctcttg tctgacacat tgagttactt ttcaggagcc atgctcactc
    23041 cgattttcat tagaattatt gggcaagacc atctggcaga agctattgga tttaaacagt
    23101 caactgttag tttagtgaaa acaatcagta atattctagg aggagtctta ttaggtattc
    23161 tatccatcca gtttatttcc ttgctgaacg ctcttacctt tttaatcgca tttttaggta
    23221 tcctcttcat aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac
    23281 tctctgtaaa atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga
    23341 ataaggtgct cttggttttg tttattatct ctactagtca agcagtgata aatgttacag
    23401 ttcctgtctc tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat
    23461 ctcttgcctt gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg
    23521 gctatctgca acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt
    23581 tgcttcttct agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct
    23641 tggatgcctt tttcgcaggt gttctctctc ctagattgca agaactcgtt tttaaacaaa
    23701 tacctgagga gtcaatggga gcagttcaat cctctatcgg tgccattacg gttgttttac
    23761 ctagcttatt tacaatagct ttggtaacca ttgctactag ctttggaact ctggcagtta
    23821 gctttgtttt attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa
    23881 gtatttagtg gagaatttct ataatatatg tttgagactg gattgccagc ctttttatga
    23941 tggtcaaaat caacagactt ttttctcttt tctgaatgtg ttataataga ctgaatct
//
LOCUS       DBEJJE010000033        23419 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEJJE010000033 DBEJJE010000000
VERSION     DBEJJE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.33"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..935
                     /gene="phtB"
                     /locus_tag="ACL3F5_001363"
     CDS             <1..935
                     /gene="phtB"
                     /locus_tag="ACL3F5_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGR0515149.1"
                     /translation="QITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHM
                     THSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKK
                     VPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVK
                     YYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEK
                     PQSEKPESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKE
                     TLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            1283..1357
                     /locus_tag="ACL3F5_001364"
                     /pseudo
     CDS             1283..1357
                     /locus_tag="ACL3F5_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            1357..1737
                     /gene="dhaM"
                     /locus_tag="ACL3F5_001365"
                     /pseudo
     CDS             1357..1737
                     /gene="dhaM"
                     /locus_tag="ACL3F5_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
     gene            2196..2909
                     /locus_tag="ACL3F5_001366"
     CDS             2196..2909
                     /locus_tag="ACL3F5_001366"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0515150.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2923..3570
                     /locus_tag="ACL3F5_001367"
     CDS             2923..3570
                     /locus_tag="ACL3F5_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515151.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNKAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3706..4359
                     /locus_tag="ACL3F5_001368"
     CDS             3706..4359
                     /locus_tag="ACL3F5_001368"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0515152.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            4369..4833
                     /locus_tag="ACL3F5_001369"
     CDS             4369..4833
                     /locus_tag="ACL3F5_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0515153.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4846..6114
                     /locus_tag="ACL3F5_001370"
     CDS             4846..6114
                     /locus_tag="ACL3F5_001370"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0515154.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            6128..6388
                     /locus_tag="ACL3F5_001371"
     CDS             6128..6388
                     /locus_tag="ACL3F5_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515155.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            6399..7760
                     /gene="pdrM"
                     /locus_tag="ACL3F5_001372"
     CDS             6399..7760
                     /gene="pdrM"
                     /locus_tag="ACL3F5_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0515156.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGIPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7914..8882
                     /locus_tag="ACL3F5_001373"
     CDS             7914..8882
                     /locus_tag="ACL3F5_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0515157.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8898..9890
                     /locus_tag="ACL3F5_001374"
     CDS             8898..9890
                     /locus_tag="ACL3F5_001374"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0515158.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            10108..11151
                     /locus_tag="ACL3F5_001375"
     CDS             10108..11151
                     /locus_tag="ACL3F5_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0515159.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            11197..12900
                     /gene="lpdA"
                     /locus_tag="ACL3F5_001376"
     CDS             11197..12900
                     /gene="lpdA"
                     /locus_tag="ACL3F5_001376"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0515160.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENISHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVSIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12964..13953
                     /locus_tag="ACL3F5_001377"
     CDS             12964..13953
                     /locus_tag="ACL3F5_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0515161.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKQLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKIEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(14026..15096)
                     /gene="xerS"
                     /locus_tag="ACL3F5_001378"
     CDS             complement(14026..15096)
                     /gene="xerS"
                     /locus_tag="ACL3F5_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0515162.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15680..17230)
                     /locus_tag="ACL3F5_001379"
     CDS             complement(15680..17230)
                     /locus_tag="ACL3F5_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0515163.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLVVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLAMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(17246..18025)
                     /locus_tag="ACL3F5_001380"
     CDS             complement(17246..18025)
                     /locus_tag="ACL3F5_001380"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0515164.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILSKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLKKLGATPIHRTSFEPVKSLVLGKKES"
     gene            complement(18012..18863)
                     /gene="ylqF"
                     /locus_tag="ACL3F5_001381"
     CDS             complement(18012..18863)
                     /gene="ylqF"
                     /locus_tag="ACL3F5_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0515165.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(19082..19258)
                     /locus_tag="ACL3F5_001382"
     CDS             complement(19082..19258)
                     /locus_tag="ACL3F5_001382"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0515166.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(19310..>23419)
                     /locus_tag="ACL3F5_001383"
     CDS             complement(19310..>23419)
                     /locus_tag="ACL3F5_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0515167.1"
                     /translation="SNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPS
                     NGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNG
                     TYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQ
                     QEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELS
                     TDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISGKDDI
                     GSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYETTAS
                     YNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSYSEGD
                     INNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGMKITD
                     AFSNKANKVFNVTLEKDEVVSKESFEERGTMLEASQIASKKAEINLLTPPIVEPLSTS
                     GKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAV
                     MMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQDDFANLAEYSIGDSGLLYTP
                     NQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQDLAN
                     SLKKLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNVKDLV
                     MYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENY
                     RKVFLPDKTNNNWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKY
                     RNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKADKDLNDFVEENARETAKRQ
                     RDHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATKVASFDDPNPAMKYFFG
                     PVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSG
                     LGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQK
                     YVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNEVYATNVVKE
                     LTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGD
                     LMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKV
                     FDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKRWPSYGTKTINNVDELQKLMDE
                     AVLQDATGTRWSNYNPETDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
BASE COUNT         6972 a         4431 c         4806 g         7210 t
ORIGIN      
        1 cgcaaattac ctacactgat gatgagattc aagtagccaa gttggcaggc aagtacacaa
       61 cagaagacgg ttatatcttt gatcctcgtg atataaccag tgatgagggg gatgcctatg
      121 taactccaca tatgacccat agccactgga ttaaaaaaga tagtttgtct gaagctgaga
      181 gagcggcagc ccaggcttat gctaaagaga aaggtttgac ccctccttcg acagatcatc
      241 aggattcagg aaatactgag gcaaaaggag cagaagctat ctacaaccgc gtgaaagcag
      301 ctaagaaggt gccacttgat cgtatgcctt acaatcttca atatactgta gaagtcaaaa
      361 acggtagttt aatcatacct cattatgacc attaccataa catcaaattt gagtggtttg
      421 acgaaggcct ttatgaggca cctaaggggt atactcttga ggatcttttg gcgactgtca
      481 agtactatgt cgaacatcca aacgaacgtc cgcattcaga taatggtttt ggtaacgcta
      541 gcgaccatgt tcaaagaaac aaaaatggtc aagctgatac caatcaaacg gaaaaaccaa
      601 acgaggagaa acctcagaca gaaaaacctg aggaagaaac ccctcgagaa gagaaaccgc
      661 aaagcgagaa accagagtct ccaaaaccaa cagaggaacc agaagaagaa tcaccagagg
      721 aatcagaaga acctcaggtc gagactgaaa aggttgaaga aaaactgaga gaggctgaag
      781 atttacttgg aaaaatccag gatccaatta tcaagtccaa tgccaaagag actctcacag
      841 gattaaaaaa taatttacta tttggcaccc aggacaacaa tactattatg gcagaagctg
      901 aaaaactatt ggctttatta aaggagagta agtaaaggta gcagcatttt ctaactccta
      961 aaaacaggat aggagaacgg gaaaacgaaa aatgagagca gaatgtgagt tctagttctc
     1021 atttttttca tgaaaatgtg caaaatatag tagattgaaa ctagaatagt atacttctac
     1081 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgttc ttatttcatt ttactatatc
     1141 ttaacagata gtgtaaataa agataaacta tttactggct aattgatcag ttaaacacta
     1201 gttaaggagt aatgatgaaa aaaagaacaa tactattatt gatggccagt ctgttagctc
     1261 ttgtcttagg agcatgtggt ttcttggaca tattgatcct ggatcattct catcaggatt
     1321 actctttact gctattttag aaactggggt ggtttgatgg aaagtattgg tattggtctt
     1381 gttatcgttt cacattccaa acacattgca gaaggtgttg ttgaactgat tagtaaagta
     1441 gctaaagatg ttccgattac ttatgtagga ggaaccgagg gcggaggaat tggaacgagt
     1501 tttgattaag tagatagggt tgtttccgaa aatccagcag atactttact tgcctttttt
     1561 gacctaggtt ctgctaaaat gaacttaaaa atggtgactg atttcagtga taaaagtatc
     1621 atcatcaaca gggttccaat tgtagaaggt gcctataatg cagctgctct tcttcaggct
     1681 ggtgcagaac tgtcagttat tcaaacacag ttagcggagc ttgaaatcaa taaataagga
     1741 attttactat aactcttttt ataggtaagc tattgattat ctcaactata aaatgttaag
     1801 taaatgattt caaaatcaga aagggattgc tttatgcagt tcctttttat tttaacagga
     1861 gtgaaactat agtgtttcta aattgtgaat caatcaaaac tgattgtgat ggggctattc
     1921 tagctttaga aaccttcaaa aattaaaatt taaggcaatc aattacttgg aagaatatga
     1981 aagcatttag tttataggaa ttctaggtct agaattacac atatatttat gaatacgggg
     2041 tgctcgatag ttagtattgt tctattctga aagatttgag ctgtcagttg tatagaaagt
     2101 gttcgaattt tttttaagtg attaaattag ttaattgtat gaggtgcttt atgatataat
     2161 gttcttaatg aattttcaga aaggaaaacc tcaaattgtt ctacaaattt ctactcttcg
     2221 acctcgacca cactcttctt gattttgatg ctgctgagga tgtggctttg acccaacttc
     2281 taaaagaaga aggagttgcg gatattcagg cttataaaga ttattacgtt cctatgaaca
     2341 aggctctctg gaaagacttg gagctgaaga aaatcagtaa acaagagctg gttaacacgc
     2401 gcttttctcg tttattttct cattttggac aggaaaaaga cggtagtttt cttgcccagc
     2461 gttaccaatt ttatctcgct cagcagggac aaacactatc gggcgctcat gatctcttgg
     2521 acagcctcat tgagcgtgat tatgacttgt atgctgcgac aaatggcatt actgccattc
     2581 agacaggacg tttggctcaa tctggtctag taccttattt caatcaagtc tttatctcag
     2641 aacagttgca aactcaaaag ccggatgctc tcttttatga aaagattggc cagcaaattg
     2701 ctggatttag taaagaaaag acgctgatga ttggagattc tctaaccgcc gacattcaag
     2761 gtggcaataa tgcggggatt gacactatct ggtataatcc tcatcacctc gaaaatcaca
     2821 cacaagccca gccgacttac gaagtctatt cttaccaaga cttgctggat tgtttagata
     2881 aaaatattct tgaaaagatc acattttaaa ggagattagc taatgactac aaaaaaagct
     2941 aatattacta ttgaagagta cattgaaatg tctgaagttg attttaataa agctgttaat
     3001 tatgaattta catctgacac ttgtcaatta gcaaatagta tttatcaatc tctttttaag
     3061 ttttttgata agaaaaattt ctctggcgat ttaattttta cttggaaatc tccatcatta
     3121 gtcaaagaag gggattatat tgggagaagg gattcacaag tagataatct tagagtaata
     3181 ggaaatatat ttccgaatta tcttactaat cgaaaatata gcctcaatat gaatcgtaat
     3241 ggctgtatag gagattttcc tcatgacttt tttgatatat acctagatca tgtagcaaaa
     3301 tatgcctacg aacaaaaagt taataatatt aaagagtatt atcctttaaa aagagcgatt
     3361 ttacaccaag agaatgcatt gtattttcga tttttttcta attttgacga ctttttagaa
     3421 aaaaattatt taaagactat atggcaagtt tctaaagaaa ctcctttttc tgaaatggat
     3481 tttaatatgt ttaaaaatat ttcagaaaag ataatcttcg aaagaggtag taaaatgctt
     3541 aatgatttaa aaagtaatta taaaaaatag ccagtcttca taaactgtat tcacgtattc
     3601 aaatcgtata tagtcgatct attaaatctt tagataaact gtaaaaagtg gtttccatag
     3661 ccactttttg ctataataga ggcagtaaaa atgaaggagt cagctatgga acactcgtct
     3721 tggcatgctt tgattaaggc gcaattacct gagggttatt tcgggaaaat caatcagttt
     3781 atggagcagg tctattctca ggggattatt tatccaccca aggaaaaggt ttttcaggct
     3841 ctcttgacaa cactgcttga agaagttaag gtggtaattc tagggcaaga cccctatcac
     3901 ggaccaggtc aagcgcaggg cttgagtttt tctgtacctg actctatccc agctccacca
     3961 tccttgcaaa atatcttgaa agaattgtca gatgatatcg gagttaagaa atctcatgat
     4021 ttgacagctt gggctgagca aggagtcttg cttcttaatg cttgtttgac tgttcctgct
     4081 ggacaggcca atggtcatgc tggtcaaatc tgggagcctt ttactgatgc tgtgattcag
     4141 gtggtcaatc atctagatag accagtcgtt tttgtactct ggggagctta tgcacgtaag
     4201 aagaaggcct tagttaccaa tcctcatcac ttgattatcg aatcagccca tccaagtcct
     4261 ttgtcggttt atagaggatt ttggggttcc aagccctttt ccaaggccaa tgcattctta
     4321 aaagagacag gacaagagcc aatcgattgg cttagataag gagaaaatat gcctcagtta
     4381 gcgacgattt gctacattga taatgggaaa gaactgctca tgctccatcg taataagaaa
     4441 cccaatgatg tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga gagaggagag
     4501 acgccccagg aatgcgcggc gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca
     4561 gttctaaaag gtgtcatcac ttttcctgaa tttacaccag atttagactg gtacacctat
     4621 gtttttaagg tgacggagtt tgagggcgac ttgattgact gcaatgaggg gatgctagaa
     4681 tgggttccct atgatgaggt tttgagcaag ccgacttggg aaggtgacca cacctttgtt
     4741 gagtggcttt tagaggataa acccttcttt tcagccaagt ttgtttatga tggggataaa
     4801 ttgttggata cccaagttga tttctatgaa taaaggagaa agcagatgct actaatcaaa
     4861 aatggtcgtg taatggatcc taagtctggt ttggatcaag tttgtgatgt cttagttcaa
     4921 gatgggaaaa ttatcaaaat tgcgcctgag atcacggaag aaggagcaga aacgattgat
     4981 gctactggtc ttgtggttgc tcctggtttg gtcgatattc atgtgcattt ccgtgaacct
     5041 ggtcaaacac ataaagaaga cattcatact ggtgccctgg cagccgctgc aggtggtttt
     5101 actactgtcg tcatgatggc taataccagt ccaaccattt cagacgtgga gactttgcaa
     5161 gcagttctcc agtcagctgc caaagagaag attaatgtca agacagttgc gaccattact
     5221 aaaaacttta atggtaaaaa cttgactgac tttaaggcgc tcttagaagc tggtgcggtt
     5281 ggtttctctg atgacggtat tccgcttgag agcagtaaga ttgtcaagga agccatggag
     5341 gaagccaaaa aactcaatac ctttatcagc cttcatgagg aagatccagg tttgaacggt
     5401 gttcttggct ttaatgaaaa tattgctaga gaacatttcc atatctgcgg tgctactggg
     5461 gtggctgagt acgctatgat ggcgcgtgat gtcatgattg cctatgcaac taaagcccat
     5521 gttcacatcc agcatttgtc taaggaagaa agtgttaaag tagtggagtt tgctcagggg
     5581 ttaggtgcag aagtcacagc agaagtagcg ccacagcatt tctctaagac agaagcactt
     5641 cttttaacac aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga atcagaccgt
     5701 cgtgccgtta tcgaaggtct caaatcaggt gtcatcacag ttattgcgac tgaccacgcg
     5761 cctcatcatg tagatgaaaa aaatgttgag gatattacca aagcgccatc tggtatgact
     5821 ggcttagaaa catccctgtc tctcggcttg acctatttag tagaagctgg tgagttgagc
     5881 ttgatggaat tacttgaaaa aatgacatac aacccagcca agctttacaa ctttgaagca
     5941 ggttacttgg ctgagaatgg tccagcagat atcactattt ttgatgccaa ggctgaccgc
     6001 cttgtggact cccattttgc ttccaaagca gctaattcac cattcatcgg tgaaacctta
     6061 aaagggcagg ttaaatatac catctgtaag ggacaaatcg tctatcaagc ttgataggag
     6121 ttagaatatg aattattttc gaaaacgtag ggagagacaa gcgaaatcta atagtggaat
     6181 ttactgtccc gcagctaatc gttccaaaat tcaatatgaa actaaagaaa aagctgacca
     6241 tgcggttcaa tatgataacg gaggtttagt tagaagctat tattgtcgta catgtgcgtg
     6301 ttggcatact acttcaaaat ctaataaacc tccgctaagt ttgaaaaact atggtctgaa
     6361 actctttggt ttagataaat cagaatagaa agagaagtat gtataagaca aagtgtttac
     6421 gagagaagtt agtattattt ttaaaaattt tcttcccaat cctgatctac caatttgcca
     6481 attattctgc ctcttttgtt gatactgcaa tgacaggtca atacaacact atggacttgg
     6541 ctggtgtatc tatggcaacc agtatctgga atcctttctt tacatttcta acagggattg
     6601 tgtcagcctt ggtgcctatc attggtcacc atcttggtcg aggcaaaaag gaagaagttg
     6661 cgtctgattt ttaccaattt atttatttgg ccttgggcct atctgtggtc ttgctgggga
     6721 tggtactttt cttggcacca acaatcttga atcatattgg gttagaagca gcagtagcgg
     6781 cagtagcggt tcgctatctt tggtttttat ctatcgggat tatccccttg ttgctcttta
     6841 gcgtcattcg ttccttgctg gattcgctgg gcttgaccaa actgtccatg tacctcatgc
     6901 ttttgttact ccctctcaat agcggattta actatctctt gatttacggt gcctttggta
     6961 ttccagaact gggaggggct ggtgctggtt taggaacatc cttggcctac tgggtcttgc
     7021 ttgggatttc tgttctggtt ttatttaaac aggagaagct caaagcctta caccttgaga
     7081 aacgaattcc acttaatatg gataacatta aggaaggagt tcgtttaggt ctgcctattg
     7141 ggggaactgt cttcgcggaa gtggctatct tttcagtggt tggcttgatt atggctaagt
     7201 tttcgtcctt gattatagct agtcaccagt cagctatgaa cttttcaagt cttatgtacg
     7261 cctttcctat gagtatctca tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca
     7321 agcgatttga tgatgcgaaa acctatattg gtctaggaag atggactgcc ctcatttttg
     7381 cggccttcac cttaaccttc ctttacattt ttaggggaaa tgtggccagt ctttatggta
     7441 acgacccaaa atttatcgat ttgacagtgc gttttttaac ttatagtctt ttcttccagt
     7501 tagcagatac ctttgcggcg ccgcttcagg gaattttgcg ggggtataag gatacagtta
     7561 ttccttttta ccttggtttg cttggttatt ggggcgtagc aatccctgtg gctacgctat
     7621 ttgattccct aacagatttt ggagcttatt cttactggat cggcttgatt attagtttga
     7681 ttgtgagcgg ggcgctctac cgttggcgtt taactgtgat tatgaagaga tttgaatctt
     7741 tagcaaaatc caaatgctaa aaagtttgtg aaaaaatatt cttgacaaga aaatcccttg
     7801 ttttcacggg gttttctttt ttattttgtg aaatttcttt tagaaaaact ttgacagtat
     7861 ttgccaaaag cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa
     7921 ctttagataa aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg
     7981 acttaaaaat tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg
     8041 ttggtgaaga ggcagctaac gtgggggcta tgttagctct caatccagat gatctgatta
     8101 cctcaaacca ccgtggacac gggcaagcta ttgctaaagg gattgacctc aacggaatga
     8161 tggctgaaat ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga tctatgcata
     8221 tcgctgacct tgatgctggg aaccttggtg ccaatggtat cgtaggtggt ggtatgggga
     8281 tcgctgtcgg tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct
     8341 tctttggaga tggtgcgacc aatgaaggtg ttttccacga agcagtgaac atggcttcta
     8401 tctggaacct gccagtcatt ttctattgca ttaacaacgg ttacggtatc tctgcggata
     8461 tcaagaaaat gaccaatata gaacatatcc atcaacgtag cgccgcttat ggaattcctg
     8521 gaatgttcat cgaagacggt aacaatgtca tcgatgtcta tgaaggattt cagaaagctg
     8581 tagaccatgt tcgcagtggc aatggtccag tcttgattga aagtgtaact tatcgctggc
     8641 tcggtcactc atcatctgac cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga
     8701 aacaaaaaga tccaatcgaa aacctccgca attaccttat tgaaaataac attgcaagtg
     8761 ccgaagaatt ggaagaaatc caagcgcaag taaaggaagc agtagaagct tctgttaaat
     8821 ttgcagagga aagcccattc ccaccgcttg aatcagcctt tgaagatatt tacgcagact
     8881 aaggaaaaag agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc attatccttg
     8941 ctatgtctga ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg
     9001 tcttcggagg agacttcggt acttctgttg gaatgcttga agaatttggt ccagaacgtg
     9061 tccgtgactg tccgatttct gaagctgcca tctctggagc agcagcagga gcagccatga
     9121 caggacttcg tccaatcgtc gatatgacct tcatggactt ctctgttatt gccatggaca
     9181 atatcgtcaa ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt caggttccaa
     9241 tgactgttcg ttgtgcagct ggtaacggag ttggctctgc cgcccagcac tcacaatctc
     9301 tagagtcttg gtttactcac attccaggac ttaaggttgt ggcacctgga acacctgcgg
     9361 acatgaaagg cctgcttaag tcttctatcc gtgataacaa cccagttatt atacttgagt
     9421 acaagtcaga atttaaccaa aaaggggaag tgccagttga tccagactac acaattccac
     9481 ttggggttgg tgaaatcaaa cgccaaggaa cggatgtaac agttgttact tatggaaaaa
     9541 tgcttcgccg tgtggttcaa gctgctgaag aattagcaga agaaggaatt tcagttgaaa
     9601 ttgttgaccc acgtaccctt gttccgcttg ataaggatat catcataaac tcagtgaaga
     9661 agactggtaa ggttgttctg gtcaacgatg cccacaaaac aagtggctat atcggtgaaa
     9721 tttcagctat tatttcagaa tcagaagcat ttgactatct agatgcacca attcgccgtt
     9781 gtgcaggaga agatgtgccg atgccttatg cacaaaacct agaaaatgca atgattccaa
     9841 cagttgaaag tatcaaagat gcaatccgaa aaacttataa caaagaatag agttacataa
     9901 gataagttat gtaaataaaa taaagctgac gagaaacttt gtatctttta ggtgcagagc
     9961 tcttcgtcat taatatctta gattagagca cgggctaaaa gctcggaaaa aagataaatc
    10021 tccttggctt catcgaagcc atcgtcgatt tcctattttt cagtcgcttt tgacgccctt
    10081 tgtatcataa atagaattgg agaggtcatg gctgatgaca agctaagagc gactcctgca
    10141 gctagaaagt tagcggatga tttagggata aacctctacg acgtttctgg ctcaggtgca
    10201 aacggtcgtg tccacaaaga agacgtggaa acttataaag acacaaacgt ggttcgcatt
    10261 tcgccacttg caaaacgaat tgccctcgaa cataacattg cttggcagga aatccaagga
    10321 accggtcatc gtggtaaaat catgaagaag gatgttttgg ccctgcttcc tgaaaatatc
    10381 gaaaacgata gcatcaaatc tcctgctcag attgaaaaag tggaagaagt ccctgataac
    10441 gtaacaccat atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc
    10501 caacgcatgg ttgaatctta cttgactgcg ccaaccttca ccctcaacta tgaagttgat
    10561 atgactgaaa tgttggctct tcgtaagaag gttcttgagc caatcatgga agcaactggg
    10621 aagaagacta ctgtaacaga ccttctttcg cttgcagttg ttaagactct tatgaaacac
    10681 ccatacatca atgcttcatt gacagaagat ggcaagacta ttatcactca caactatgtc
    10741 aatcttgcca tggcagttgg gatggataat ggattgatga cacctgttgt ttacaatgct
    10801 gagaagatga gtctttcaga actggttgta gcctttaagg atgttattgg ccgtaccttg
    10861 gatggtaaat tggctccaag tgagttacaa aattcaacat tcacaatcag taatttggga
    10921 atgtttggtg ttcagtcctt tggcccgatt attaaccaac ccaactcagc tatccttggt
    10981 gtcagttcga caatcgagaa gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc
    11041 atgagtttag gattaaccat tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt
    11101 atgaaggact tgaaagagtt gattgaaacg ccaatctcaa tgttaattta agagcaagag
    11161 tattcatttt taagatatag ataaaggaag gaagacatgg ccttagaagt aattatgcca
    11221 aaagccggcg tggatatgac agaaggacaa atcgtccaat ggaataaaaa agtcggagaa
    11281 tttgtaaaag aaggagaaat ccttttggaa atcatgactg ataaagtcag catggaattg
    11341 gaagccgaag aaaatgggta cttgattgcc attctcaaag gagatggtga aactgtccct
    11401 gtaacggaag ttatcggtta ccttggtgaa gaaagggaaa acatcccaac agctggagca
    11461 gcatcgccag aagctagccc tgtacctgta gcaagtacct caaacgatga tggtaagagc
    11521 gatgatgctt ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt tgcagccatt
    11581 aaagctgccc aactcggcgg taaggttgcc cttgttgaga aatctgaact tggtggaacc
    11641 tgcttaaacc gtggatgtat tccaaccaag acctaccttc ataacgctga aattattgaa
    11701 aatatcagtc atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt cactgttgat
    11761 atggaaaaac ttttagaaac taaatctaaa gttgttaata ctcttgttgg tggtgttgca
    11821 ggtcttcttc gtagctacgg agttactgtt cataaaggaa ttggtacaat cactaaagac
    11881 aagaacgtct tggtaaatgg ttctgaattg cttgaaacca agaaaatcat tcttgctggt
    11941 ggttcaaaag tcagcaagat caacgtccct ggtatgcaat ctccacttgt catgactagt
    12001 gatgacattc ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt
    12061 gtcggtatcg aactcggtca ggccttcatg acatttggtt caaaagtgac tgttatcgaa
    12121 atgatggacc gtatagttcc agctatggat gcggaagttt ctaagaacct tcgcttgatc
    12181 cttgagcgta aaggaatgac catcttgact ggtactaaac tgcaagaaat cattgaggaa
    12241 aatggtcaac ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag caaagctctt
    12301 ctttcaattg gtcgtatgcc agaccttgaa ggtattggag aggttgagtt tgaattggat
    12361 cgtggttgta tcaaggtcaa cgaatacatg gaaacttcag ttccaggcat ttatgcacca
    12421 ggtgacatca acggtactaa gatgttggct cacgcagctt tccgcatggg tgaagtttcc
    12481 gctgaaaatg cccttaaagg aaatcatgca gttgccaaat tgaatttgac tcctgcagcc
    12541 atctacactc tccctgaagt agcagcagta ggtttgacag aagaacaagc ccgtgagaaa
    12601 tacgatgttt ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat tgcatctgac
    12661 gcagctcaag gtttcgtaaa agttatcgct gataagaaat acggagaaat ccttggtgta
    12721 cacattattg gtcctgcagc cgcagaatta ataaacgaag catcaagcat catcgaaatg
    12781 gaaattactg ttgaggaaat gctgaagacc atccacgggc acccaactta ctctgaagtg
    12841 atgtacgaag cgtttgcaga tgttctagga atggccatcc attcacctaa gaaaaaataa
    12901 aacgaagata gattagactg gaaggttatt tccagtttct atcatataaa gtaaagggat
    12961 atcatgaaat acattatcaa tcattcaaat gacactgctt ttaatattgc cttggaagaa
    13021 tacgccttta aacaactttt ggatgaggat caaatcttcc tactttggat taacaagcca
    13081 tctatcattg ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc
    13141 gaaaatggta ttgaggtagt tcgccgtatt agtggtggtg gagctgttta ccacgattta
    13201 aataacctca actacacgat catctccaaa gaagatgaaa ataaggcatt tgacttcaag
    13261 agcttctcaa ctccggttat caataccctg gctcaacttg gggttaaagc tgagttcaca
    13321 ggtcgtaatg accttgagat tgatggtaag aagttctgtg gcaatgccca agcctatatc
    13381 aacggccgta tcatgcacca cggttgcttg ctctttgacg ttgatttgtc agtcctcgca
    13441 aatgccctta aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc
    13501 cgtgtaacca atattatcaa tgaattacca aaaaaaatca cagtcgaaaa attccgtgat
    13561 ttactcttgg aatacatgaa aaaagagtac ccagagatga ctgaatacgt cttttcagaa
    13621 gaagaattgg ccgaaatcaa tcacatcaag gatactaagt ttggaacttg ggactggaac
    13681 tatggtaaat cacctgaatt taacgtccgt cgtggaacca aattcactag tggtaagatt
    13741 gaagtctttg ctaacgttac tgaatcaaaa atccaagaca tcaagattta tggtgacttc
    13801 tttggtattg aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc
    13861 gaagatgttc ttaaggcgct aaaaaccatt gatatcacac gctacttcgc tggtattagc
    13921 cgtgaagaaa tcgctgaagc ggtagttgga taaatcaaaa agaagttggc caactaacca
    13981 acttcttttt ttgatattta tttacataat ttaaaatacg taaaatcata aactatccag
    14041 agcattcttt tgttcatcat taacaatatg ggtatagagg tcagtgactt gtgtgctggc
    14101 atgtcctagt tggtgactga ctaaaacttg tgatttagta gcatcataga gcctagttgc
    14161 tagtgtatgg cgcagtttat ggggtgttac acgtacttta aaatcctctg agtatttagc
    14221 aaccattttc tcaacgctag aagcatcgat acgattagga acacctctgt agagagttaa
    14281 aaaaagggct gtatctgttt tttccgtttt atagcgttga ttccgaatgg ccagataatt
    14341 ctctaaataa ggtttagcaa aagcagcgac attgactgag tcacgtttgc caccttttcg
    14401 agtaacatca ataaccatca tttttagatt gagatctctt agatctagat taacagcttc
    14461 agataagcga acaccagatg ccaagagaag ggcaataatg gctaaatctc gttctttatt
    14521 tttgttgaat gatgagagag ctcgatttga aagctgttgt gggtgctctt gatcgatata
    14581 agttagaaaa ccttctgttt catcacctag aaagagtttt tgcttgatat tttcagctct
    14641 ggcagcaagg gtttctttct ttttcttggt tgaaactttt ttcattacat tacgatagaa
    14701 ataaggttcc ccctgatcgt tttcaacctc ctcggttaga tacttgtaaa gactagaaag
    14761 tgctgataag gttcgattga tagttgtctg tgaaacacct tgttttgttg tattagcatt
    14821 cagcaaggga cgttcacgta gataaaggat aaaggattcc atgtctttct tagacatatt
    14881 ttccaaaact gataaaggaa tatcggatat tttatcagcg tttgaaatac cagactccaa
    14941 aacccagctg aaaaatcggt catattcctt aaggtattcg tacagggttg taaaactgta
    15001 gggcacagcc agtttagatt ggtagtattc cagaacatac cagggcatga gttgttttag
    15061 tttgtcgatt cgttccagta aaatctcacg tttcatgtat tttctccata attaagtata
    15121 ctagtagtat agcatagact tgtatatttt tcaagaaaat tatagttttt cagaaagatg
    15181 ttataggagt ttttcaaagt gataaaaaga cttagaccta caaacaaaac agaataagga
    15241 aaataatgaa aatctcaccc actaaacttc tgttaatact acataactga agagctatat
    15301 aaggagctat gagatacaaa acacattgta taatagattg aaactagaat agtacatctg
    15361 gacttctaaa acattgctag aaattgattt gattgtcctg attgttttat cctatttcta
    15421 tttcatttca ctatataatt gctattgttt tctttttcat gattttaatc ttactgtaca
    15481 gatttgatac agtaaactcc tttctagctt tatgctttat catttctaac ttaattatag
    15541 tcttattttt aataaagttc aattatttat atgtaaaatt cctcattagt aaaaaataac
    15601 cgatctcatt tctgagaatc ggttttctaa ataaatcaaa ctgatcattt acataattta
    15661 tgttatgtaa atgattatac tacaacaaca aatctttgac ttttccaatt tcactttttg
    15721 gaataaccag gtgaatcata tcacccagat acattctggt tgagccgtta actgtttggc
    15781 tcttgccatt atggacttga gttgtgatga ggacgttgtg tggtaagttg agttcatgaa
    15841 cttgtttccc agcaatttta tcagaaactg gtatttcgat aagtgtaact tctccttcgc
    15901 tagatacttc ttctggaagc attttttcca gcatggcttc atagactggc gtacctttga
    15961 gcaaatccat gataatataa gaaacaagag tgacaagacc aagtggcata aggttgcgaa
    16021 tatctcctac catctcagtt acgaggatca tagcggttaa gggagctttt gatatggctc
    16081 caaaatagcc actcattcct agaatgacaa atatagggaa ttgctcttga ctgacaagtc
    16141 caagattgac acagatagca ccaattaagg caccaagcaa agaaccaaga gctaaaatgg
    16201 ggaggaaaat tcctcctggc agtccacttc catagctaat catactccaa ataaagcgga
    16261 tcaaaaagta agctaataaa acttggaaac taaaattttg ttcagttaaa gaaaggacaa
    16321 gctgatttcc gccaccaatg atttgaggta agaagattcc gactggtatg ataaggataa
    16381 aagccaagat gggataataa gctctatcca aatggatttt ttgaccaatc aagtcataaa
    16441 ctcttccaac gtttaataca gctttctcat agagaaagcc tgaaaatcca aggaaaattc
    16501 ccatggcgag atatatccaa tactgatcta gggtcatggg aggaatgtta tctggcatat
    16561 ccaatactgg tgtcaaaccg aacatgagta gagacacaaa gtttgctacg atgctggctg
    16621 ctagagttga gacccagaaa aagcgcgaaa aatggtgata gacttcttct acaacaaaga
    16681 gaagtgctgc aataggagca ttaaaggctg cggctaaacc tgctgcagct ccactggcaa
    16741 tcaaggaacg ttcctctact ggactagatt tgagccactt agcaattcct ttaccaccaa
    16801 ctgctccaag ttgaatactg ggtccctctc gacccaacat gagtccactg gcaatagcaa
    16861 gaatacctag cacatatttt ttccaaagaa tgccccacca gttgagggac atgaggcctt
    16921 tcagttcggc ttcgacttga ggaattcctg agcctttaat atctttttct gaccgtgtta
    16981 gtttggcact gagccaacag atgagtatat aaaacaaaac cagtacaaaa agattgcgca
    17041 ctaagtaccc ttgatcttga taaactcctt gtatcaggtg gaagcccttt tcaattaaga
    17101 aacgaaagga tccgacgata attccaacga cgaggccgac aatgattcct cgaccaactt
    17161 gggatagtat agtgctggat gcaaaggcga attctttctt agaacggact atttccgact
    17221 gttcctccat ggtatttcct ttcaattaac tttctttttt acctaaaacc agtgatttaa
    17281 cgggttcaaa gctggttcgg tgaattgggg tagctcctag ttttttgagg ccttccagat
    17341 gtttagctgt gccatatcct gcattagtag cgaaatcata gccagggaac tgctgatcgt
    17401 attctttcat caattcatca cgtgttacct tggctactat agatgctgct gcgatagaga
    17461 gggagttggc atctcctttg ataatggagg tttgtgaaat gggcaagtcc agtttcatgg
    17521 catcaatcaa aaggtgctct ggttgagggc tgagctggga gattgcttct tgcatggcta
    17581 gtttggttgc ttcatagatg ttgacttggt cgatgacctg attatctatg ataccaattc
    17641 caatcgacaa ggcttggtct tgaacggctt ggaaaatctc cagatgtttc tttttaggaa
    17701 ttttcttgct gtcgttgaga cctttaatct tacaattttt agataaaata acggccgcag
    17761 cgactacagg accagcaaga ggaccacgac caacctcatc aatacctgca attaaggtca
    17821 atccttgctt ataaagttct ttttcataag aaagcatgga ttccaagcgc aaattttcat
    17881 ctaattcagc ttgaatggct cttttacgct tgctgatttc cttttgaact cctgagcgat
    17941 tatccttttc aagctctaaa aaaatagggc tttctaactc cttgactgtc acaaggaatt
    18001 ctttgatttc tttaatcgtt gccatcgagg tcttccaatg tatctaaggt atagttaccg
    18061 agtttgccat cacggacttc cttcacgaag agactgtaaa aacggtcata gtcatcacgg
    18121 aaaccgaggg cgcgggtcat atccataata atcacaggcg cttcttcttc aattttcatt
    18181 tgtttgaagc gttcagccag cttttctgga taatgttctt tgaaataatt gataccaaaa
    18241 atggtaacct catccatagg aagcaactgg tctttgatag ctccagtcaa tgccaactta
    18301 agtgcaacag tttcatcctc aaacttaggc cagagaatcc ccggtgtatc caagatttcc
    18361 aggtctttat tggttttaag ccattgttga ccttttgtga cccctggctt gtttccaaca
    18421 acagcaatct ttttaccagc caaacggttc atcagagttg atttaccagc gtttggaatc
    18481 ccgataatca tagtacgcaa ggtttcaatc tgaatcccac gttctttctg gcgagcaatc
    18541 ttatcagcca tgagcttctt ggccgcatct gttacaactt ttacagtcac ttgctctttg
    18601 gagttgatag ctagcgtctg gattccttgt gattcaaaat actgacgcca ttccttggtc
    18661 attgctggat cagccaagtc ggccttgttt aaaatcaaga gttttggttt atcaccaaca
    18721 atcttggtca acataggatt ttgactagat agaggcaagc gtgcatctac taaaatcgtc
    18781 acaaaatcaa caaattttaa attctcctgc acctgtcgac gagctttaga catgtgacca
    18841 ggaaaccatt gaatagtagc cattgagttt tttcctttca tagcaaggat ttagatcccc
    18901 tattttattt tactattgtt tgaacataga gagttttcaa atgaatgatg tccaaacagt
    18961 tcttgtttta tgacatagaa atctacttta tattatatca tgccttcttt attttgtccg
    19021 atgatagcct tttaccctat cttttaccct atatagaaaa aagccatcaa atgatgactt
    19081 ttcagaggga gcaaaaaact gttcccgtca tattatgaac caaaagaact aaactaccaa
    19141 cagctaatag gcctaaagct gtaagctcag aagttgatga acctgttgca ggaagagttt
    19201 cctgctgata aataagatca taacttactt cattatcagt aggaattcct gcttgaatct
    19261 tggtttgttc ttcatcacct ttttaaactt tatttcctaa tagtaaacac tattttttat
    19321 tctcaaaaat tgaacttcta aaatcatttg tttggtcaag ataggcttta aagattgctc
    19381 tcttcaactt atggacggca ctgtccgttt ctggattata attactccaa cgtgtacctg
    19441 tagcatcctg caaaacagct tcatccatta gtttctgcaa ttcatccaca ttattgatag
    19501 tctttgtgcc atagcttggc catcgttttg tcggatcttt aaaggtcacc tgcttcaagt
    19561 ttccaaactg atccacccgt tcttggtaca tagctgtctt aaattctgcc caagttttat
    19621 acttaccatc aaataccttt ttcaaaacaa gctcatcggt caccaagccc cgttctttac
    19681 cataaagatt gatagtttgc ccttgttgtt tagcatcttc ttcgtattgg ttggaaatat
    19741 atggtaccat accatcctta aagcctttgg cagccaaaag ttcgtacgca atcctacgtc
    19801 ccataaggtc ccctggtgtg cctttctcac tgctgagagc tgaatagatt ggggcaaaga
    19861 gtttgatggt atagtagcca tttcgttcat agtcgccaga ctggtactca cgagctgata
    19921 agatgttatg gtcaatcaaa ctttcaaaac tattcaggtt tcgggcctct gcttctgtca
    19981 attctttgac tacgttagtg gcataaacct catttccatc tgcaggatct ttcacgtatt
    20041 tattctcaat ttttctcagg gccgtcattt tctgataagc atctaactgt ttcacgatag
    20101 attgcccttc gagatattcc aacatgtaaa cgacatcaaa catattgtgg acgtattttt
    20161 gaagatctgt tgcgtcttta aatctcgtag ttggatcaag tacttgtaat cgttctcctt
    20221 ctttactatc agattttgaa tgtttcaata tagaattgat agtaatcgtt gcatcacttg
    20281 gttggtctgg tgcttgtagt aagcctttag caaagaactc aggtccaagt ccacttcttc
    20341 ttccataacc accaagataa atatcttgat ctgaattatg cgtcatctca tgagtatacg
    20401 taatagctcc atccttatct agcatgcgat accccatata atatactgca tcccctgtag
    20461 cataagcacc atgtccatta tgaccaactt tatttccaac aggaccgaag aaatatttca
    20521 tcgcaggatt tggatcatca aaacttgcta cttttgtagc tttccctacg gtattatcat
    20581 cgccaaattt ataagcatcg taaagcaaaa tatttctata aagtttttca cgtgcattgt
    20641 cgtctaaaat acgataccaa taatcgtagt gatctcgctg acgtttggct gtttcacgtg
    20701 cattttcttc aacaaaatca ttgaggtcct tgtctgcttt gtgctcacta ttgcggtaac
    20761 gatcataagc tccaaatcct agactagaga tggtcgagat gacaaagact gatttctccg
    20821 gcaaggttag gagcggcaag accatattgc ggtatttcca tgtggcacta gtgatacggt
    20881 catagacacc aatagaatac ttagtgccaa ctagtccttg cttcgttttc acctcttcga
    20941 tattggattt ttcttcgaca atgtaagcct tagtctgtga tttaaaccag ttattattgg
    21001 ttttgtctgg tagaaagact tttcggtaat tttccaacgt gctaaacaaa tctgtcgttc
    21061 catgatggct ggcaaggctg atagcataag tatcgacatt gtttttagca agaagattgt
    21121 taaagccaga tttacctaac tcaatcagag tatctaatgg tgaagtattt cctttaccaa
    21181 agaagtccgg atgatacata actaggtctt tgacattcac ctgaccatag ctaaagttat
    21241 accaacgttc taaataagtt aaaccgagta gtaaggcttc cttattgttc ttgattttat
    21301 ctacaagata gcctctggta actgggttgt caccagcaag tccagcatct gcagacaaga
    21361 gttttttcaa actgtttgcc aaatcttgct ttgttttggt aaactggtct tccatataga
    21421 gctcagtttg cttgacctct ggagaaattc cgagtgtctt tctgatagct tctgaatcgt
    21481 aggcaacctg ctgtaattca ggtaaaactt gattgatgat agagtcttgg tcatacaaga
    21541 attgatttgg cgtatagaga agcccactat ctccaatgct atattctgcc aaattggcaa
    21601 aatcatcctg gtacctgaga tcaaactttt cagatgaatg gtccttgtag tgaagcaaga
    21661 gtttgtttgc agtctgtttg ttggaaataa tatctgtgat tacttggtca tccttcatca
    21721 taactgcaga caagagttct ttttgatata agatactgtt ctccttaacc aggtttccgt
    21781 atttcacgat ggtcgccttg ttatagaaag gtaacaattt ttcaatgttc ttataaacca
    21841 aagcacggtt ggcttgataa tgggctatct tagaaaaatc actgtctttc ttaccgcttg
    21901 ttgagagggg ttccactatt ggtggagtga gaagattgat ttctgctttt ttgcttgcaa
    21961 tttgagaagc ctctagcatt gttcctcttt cctcaaagga ttctttgcta acgacctcat
    22021 ccttctctaa agtgacattg aaaactttat tcgctttatt actaaatgca tcagtaattt
    22081 tcattccatt ataatggtaa ccactaatgg catttccatt agttacattg acatcactaa
    22141 gcacattagt caatcttcca gcatgatttt cactatttga ttcacgatcc cataagttac
    22201 ctgctatacc agcaactttt ccaaaacgtt ggctattatt aatatcccct tcagaatagc
    22261 tattctgaat atgcgcatct ttgtctacaa gaccagcgat acctccaacg gtctggtcag
    22321 aactatttgt atttgatgaa atgaccactg tcgcttttga cttagtcagt gaagctttgc
    22381 ttcctgtcaa atgaccgacc aggccaccga tattatagga agcagttgtt tcataggtat
    22441 tgacaattct tcccttgaaa ctactctctg tgatgcttga ttgatctgcc ttagccaaca
    22501 aaccaccgat accacgttca ccggcaagta caccatccac atgaacttgc ttaatttttg
    22561 tgttattctg agcttcattt gccagtgaac cgatatcatc tttccctgaa atagagacat
    22621 ttttcagact caacttttct attgtggccc ctctcaagct ttcaaaaaga ggctttttca
    22681 agttgtaaat agcataatgc ttaccatctt tttcaccaat caactgacca gtaaaggttc
    22741 ccttgatata ggatttatca tcagtgctaa gctccacttc gttagcattc aggctagctc
    22801 ctaaatgata ggttccagag agattttggt ttatagcttt gaccagatta ctaaaggaag
    22861 taaagtttgt tgtttcttct gttcccttct tagctagata gaaggtaaaa ttatctttat
    22921 atctgctttc tatctcctgc tgaagcttct ctacttttgc tgtgatttta taaaggattt
    22981 tatcattttt tctttcctct gatattgatg ctactggtag gtatacatct ttgaatgaag
    23041 aagatttcac tttaacaaag tagctatttg gattgcttgg aacttgttct aacgaaatgt
    23101 gttgtttata agtaccattt gacaaactgt ataactctag gtcggaaaca tttcttaatt
    23161 caagtgtttt ctctggatct tctacctttt tatcggggtc tagttcattt tcttgtttaa
    23221 tttcttcgtt tccatttgaa ttggatgtgt ttgatttggt tgaaacatcc tcagttgaat
    23281 ttccgtttga tggttctggt tctgtttgtc cattctctga tgttgtatta cctgaatttt
    23341 ctggttttgt tgcagttccg tttttttctg gttgatttga ttcttcaact ggtggttttg
    23401 aatcactagg tttattgga
//
LOCUS       DBEJJE010000034        22291 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEJJE010000034 DBEJJE010000000
VERSION     DBEJJE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.34"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..472
                     /locus_tag="ACL3F5_001384"
     CDS             <1..472
                     /locus_tag="ACL3F5_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515168.1"
                     /translation="NYEKFDIIAKNADNFKKFAELTHTIGNFIVLPHWMNTGRYNFSK
                     DYWDLTLLSLYEWFNAFLTEDESWKKFIKNYYLQPYVNSNYQPEIFWENHSFRNKELE
                     GTEEFSIFLKKVNERIEERGKFIIKQICDKLDQKDFNFYKEIKNMETIRFSNEF"
     gene            485..955
                     /locus_tag="ACL3F5_001385"
     CDS             485..955
                     /locus_tag="ACL3F5_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515169.1"
                     /translation="MVRVYKSVRLAYEAKVWIDELIQKKERKIKELNQDNFLNTLEQT
                     LLSNHYDELNGVSFNIVLKASIGSIIEEAYRNTKYYSIAKWQNLRQKMEKDIKTVNPS
                     LETSVTPRLYLDENVLNGLDEFRYHLMKEDGATRLPRLSYIIKLVVYSYWKTQQ"
     gene            1028..2347
                     /locus_tag="ACL3F5_001386"
     CDS             1028..2347
                     /locus_tag="ACL3F5_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGR0515170.1"
                     /translation="MFKLKKEANLKRNYFITSSRLKLLHLIIITFSILVLLGLIVSIR
                     APAFIQILCIVFGILAIYKINNKLKDFRYELDFDLIIRESLLLVLYTNHLYTSEKDNS
                     GYEEIIRSAILKYELDNQNSRIIIKALIRGDEFSKKVQTLDDVLAGVLELELEEKITH
                     PNIVEYHFYYKKPDRLILSPHNHKKEIDSLDIDLGYDITYNPIKCPHILVSGGTGSGK
                     SIFISFLIIELLKRNSTLYIADPKNSDLGSLSHYLSDKYIATTPNNIARIVRLVVEQM
                     QERYQAMRDNFHYGSNFADHGFKPVWLIFDEMGAFQASATDKKSKEVITEAMDGIKQI
                     ILLGRQAGVFILISAQQMRAETLNTDLRDNLGLRIALGANSIEGYRMVFGTATPDKFK
                     SIEEKGAGYLYMQGSGKEKAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            2443..2757
                     /locus_tag="ACL3F5_001387"
     CDS             2443..2757
                     /locus_tag="ACL3F5_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515171.1"
                     /translation="MKINDFLKPELLGNKFVAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQIKVNTLSPTATPQLLSDKKTCPVKLSNLTVGQFNGNLWFSCNDVVPI
                     SK"
     gene            2774..3502
                     /locus_tag="ACL3F5_001388"
     CDS             2774..3502
                     /locus_tag="ACL3F5_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0515172.1"
                     /translation="MAKLFAISDIHGHLDEFISALSKVDLSDKNNRLILIGDYIDNGL
                     QSFQVISKIIKLEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYKDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDKTYQGKIYFDGKNHYFI
                     DGDVYHSKTIPVICYDTVTKSYQY"
     gene            3577..4350
                     /locus_tag="ACL3F5_001389"
     CDS             3577..4350
                     /locus_tag="ACL3F5_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0515173.1"
                     /translation="MKTLLIGDLHLKSQLILPIIDKIIQTHNIKRVIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIEVINLIGNHDAYYLLGDQAPFSIQNLEVFFAV
                     QGLLQDLKLQVAYQLDDYLVSHAGFNQIFDPQKWHFFPYTKEHEEELDILAYTIGPMR
                     GGEALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNIIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTDWATDQTLKQLPKPQI"
     gene            4522..5316
                     /locus_tag="ACL3F5_001390"
     CDS             4522..5316
                     /locus_tag="ACL3F5_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HGR0515174.1"
                     /translation="MSYNRKIIRTSSYLEIWEYESPIFSNDTTQIDEEHISLKEKKKR
                     RTFEELTTAEQDERIKRISNTRKNSKWKLQRLIDTNFDDRTSFLTLTTKENIQNRYEF
                     NLLFDKFIKRLNYHIYHSKKRLIKYIAVLERQKRGAWHAHILLFSFPFIPHKELLTIW
                     GLGAVRINKLNKLDDSSNAGRYVAKYMEKGIGQELLESLGKKAFYSSRNLQKPEEIKL
                     FTSESLDNLVKNEDILYESNYISKVFRKGHLIDNKVKYKKIKLSKE"
     gene            5324..5593
                     /locus_tag="ACL3F5_001391"
     CDS             5324..5593
                     /locus_tag="ACL3F5_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0515175.1"
                     /translation="MQVILPTEQVQEIQSMITNLLQNEISHFKEDLGLDSPYLNKGQT
                     CKYLGISNNTLDGWIQKGLPVIKIGKTVRFNKNEIDKWLCRKAML"
     gene            5635..6855
                     /locus_tag="ACL3F5_001392"
     CDS             5635..6855
                     /locus_tag="ACL3F5_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0515176.1"
                     /translation="MTVTKTNSNTYNLKVYIPKEIRPKMGIKGNHFVKRYKTRKEAKE
                     AELEILTKIHQLENGEDILLSKTNDILFSEFFNNIWWDSYKAGQTTSTTKPPTQVTID
                     NTKTVFRKHILPMFGNYSINFLNQNKQVVLNLMTAKAEEYANFKVIRSYVNSIFDWAE
                     ELEYIESNRLSKTIKRIKATKKLKLQDSKNEEDLYLSSEELQDWFDAFREDLENDKLS
                     LKDYVLFFTTFILSDRKSESYALHWKNIDLANAQIDLRHALDKYKNVKSTKGNKKTIF
                     SIPSYLVSLLSEWKKQQKYELAKFGIMQTSDQLVFTYIDTKGNVNSPLHVDYLNNKMN
                     SVKRRHPKLKHATPHKLRHTGATLAKKAGMSLEAISEALTHSDTITTKTYVNASNIVP
                     LSAGQVAYQHLKNK"
     gene            complement(6963..7355)
                     /gene="rpsI"
                     /locus_tag="ACL3F5_001393"
     CDS             complement(6963..7355)
                     /gene="rpsI"
                     /locus_tag="ACL3F5_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0515177.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(7374..7820)
                     /gene="rplM"
                     /locus_tag="ACL3F5_001394"
     CDS             complement(7374..7820)
                     /gene="rplM"
                     /locus_tag="ACL3F5_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0515178.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            8177..8494
                     /locus_tag="ACL3F5_001395"
     CDS             8177..8494
                     /locus_tag="ACL3F5_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0515179.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(8645..9457)
                     /gene="folK"
                     /locus_tag="ACL3F5_001396"
     CDS             complement(8645..9457)
                     /gene="folK"
                     /locus_tag="ACL3F5_001396"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR0515180.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLCDALKK"
     gene            complement(9500..10054)
                     /gene="folE"
                     /locus_tag="ACL3F5_001397"
     CDS             complement(9500..10054)
                     /gene="folE"
                     /locus_tag="ACL3F5_001397"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0515181.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(10035..11357)
                     /locus_tag="ACL3F5_001398"
     CDS             complement(10035..11357)
                     /locus_tag="ACL3F5_001398"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0515182.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(11359..12333)
                     /gene="folP"
                     /locus_tag="ACL3F5_001399"
     CDS             complement(11359..12333)
                     /gene="folP"
                     /locus_tag="ACL3F5_001399"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0515183.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGKFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(12428..13135)
                     /locus_tag="ACL3F5_001400"
     CDS             complement(12428..13135)
                     /locus_tag="ACL3F5_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0515184.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(13188..14606)
                     /locus_tag="ACL3F5_001401"
     CDS             complement(13188..14606)
                     /locus_tag="ACL3F5_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0515185.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            14796..15608
                     /locus_tag="ACL3F5_001402"
     CDS             14796..15608
                     /locus_tag="ACL3F5_001402"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0515186.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEVFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            15947..16966
                     /gene="adhP"
                     /locus_tag="ACL3F5_001403"
     CDS             15947..16966
                     /gene="adhP"
                     /locus_tag="ACL3F5_001403"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0515187.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            17200..18189
                     /locus_tag="ACL3F5_001404"
     CDS             17200..18189
                     /locus_tag="ACL3F5_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515188.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            18217..19020
                     /locus_tag="ACL3F5_001405"
     CDS             18217..19020
                     /locus_tag="ACL3F5_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0515189.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            19044..19955
                     /locus_tag="ACL3F5_001406"
     CDS             19044..19955
                     /locus_tag="ACL3F5_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0515190.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(20011..21345)
                     /gene="pepC"
                     /locus_tag="ACL3F5_001407"
     CDS             complement(20011..21345)
                     /gene="pepC"
                     /locus_tag="ACL3F5_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0515191.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(21563..22285)
                     /locus_tag="ACL3F5_001408"
     CDS             complement(21563..22285)
                     /locus_tag="ACL3F5_001408"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0515192.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT         7040 a         4510 c         4139 g         6602 t
ORIGIN      
        1 aaattatgaa aaatttgata ttatcgctaa aaatgcagat aattttaaaa aatttgctga
       61 actaactcac acaattggga actttattgt attacctcat tggatgaata ctggtcgata
      121 taatttttca aaagattact gggatcttac tttactttct ttatatgaat ggtttaatgc
      181 tttcttaact gaagatgaat cttggaaaaa atttattaaa aactattact tacaaccata
      241 tgtaaatagt aattatcagc ctgaaatttt ttgggaaaat cattccttta gaaacaaaga
      301 gctagaaggt acggaggaat tctcaatttt cctcaaaaaa gtcaatgagc gaattgaaga
      361 acgtggtaaa tttatcatta aacaaatctg tgataagtta gatcaaaaag atttcaattt
      421 ctataaggaa attaaaaata tggagacaat aagattttct aatgaatttt aaaaaggagg
      481 atttgtggtc agagtatata aaagtgttcg tcttgcatac gaagccaaag tatggataga
      541 tgagcttatt caaaaaaaag agcgtaaaat caaagaacta aatcaggata attttctaaa
      601 taccctagaa caaacacttc tatcaaatca ttacgatgaa ttaaatggtg tttcttttaa
      661 tatcgtttta aaagcttcta tcggaagtat tattgaagaa gcatatagaa atacaaaata
      721 ttactccatt gctaaatggc agaatttgcg tcaaaaaatg gaaaaagata tcaaaactgt
      781 caatcctagt ctagaaacat cggtaacccc tagactctat ttagatgaaa atgttctaaa
      841 tggtcttgat gaatttcgat atcatttaat gaaagaagat ggtgctacta gattaccaag
      901 gcttagttac atcattaaac ttgttgttta ttcctattgg aagacacaac aataacctaa
      961 gcaaaacctg cttaggtccc ttataaaaac aaatgtatat gtgttatact acataagagg
     1021 actttttatg tttaaattaa aaaaagaagc taacttaaaa agaaattatt ttattacaag
     1081 ttcacgttta aaattgttac atctgataat aattaccttt tctatccttg ttttattagg
     1141 tttaatagta agtattagag ctcctgcttt tattcaaatc ttatgtattg tctttggtat
     1201 tctagcaatc tataaaataa ataataaatt aaaagatttt agatacgaac tagattttga
     1261 tttaattatc agggaaagct tactacttgt tttatataca aatcatctct acacttcgga
     1321 aaaggataat tcaggttacg aagaaattat tagaagtgcg attttaaaat atgaattaga
     1381 taatcaaaac agtcgtatta tcattaaagc gcttatcaga ggtgacgaat ttagtaaaaa
     1441 ggttcagaca cttgatgatg tattagctgg agttctagaa cttgaactag aagaaaaaat
     1501 tactcatcct aatattgttg aatatcactt ttattacaag aaacctgata gactaatatt
     1561 atcaccccat aatcataaaa aagagataga tagtcttgat atagacttag gatatgatat
     1621 aacttataat cctataaaat gtcctcatat tttagtttca ggtggtacag gtagtggaaa
     1681 atctatattt atatctttct taattattga acttcttaaa agaaattcaa cactatatat
     1741 tgcagatcct aagaacagtg atttaggtag tctatctcat tatttaagtg ataaatatat
     1801 agctacaact cccaataata ttgctcgtat tgtacgtttg gtagttgaac aaatgcagga
     1861 acgatatcaa gccatgcgtg ataactttca ttacggttca aattttgccg atcatggatt
     1921 taaaccagta tggcttatat ttgatgaaat gggagcattt caagcttcgg caacagataa
     1981 aaaatctaaa gaagttatca ctgaagcaat ggacggtatt aaacaaatta ttctactagg
     2041 gcgacaagca ggagtattta tccttatatc tgctcaacaa atgagagctg aaactctcaa
     2101 cactgatctt agagataatt taggactaag aatagcttta ggagcaaact caatagaggg
     2161 ataccgcatg gtatttggca cggctacacc tgataagttt aaatctattg aagaaaaagg
     2221 agcaggatat ctttatatgc agggctcagg aaaagaaaaa gctcaatatt gggaaagccc
     2281 ctatcttgat acaacacaat tcgattttat aaaagaacta caattatacg taacaaagtc
     2341 aaaataattt caatagatat ttttgcttaa attcaataga ttttcagcaa aaatatctat
     2401 tcctcatcgc ttaagcgatg acaaaaagaa acgaggtatt atatgaaaat taacgatttt
     2461 cttaaaccag aattattagg caataaattc gtggcagtaa aaggatatac agaagttttg
     2521 gacagagaaa caaataaacc tgtagcacta cgtcttaatg tttcaattca agatgaggat
     2581 tctgatttct ttatggaaat gatccagata aaagttaata cgttatctcc tacggctact
     2641 cctcaattat tatcagataa aaaaacatgc cccgttaaat tatctaattt aacagttgga
     2701 caatttaacg gaaatttatg gttttcttgt aacgatgtag tccctatttc taaataattc
     2761 ggtgatacta tttatggcta aactttttgc aatatctgat atacacggtc acctagatga
     2821 gttcataagt gctctcagta aagtagacct atctgataaa aacaatcgtc ttattctaat
     2881 cggagactat attgataatg gacttcaatc ttttcaagtc atttccaaaa taatcaaact
     2941 tgaggagatt tatcctaatc aaattattac tcttctaggg aaccatgaag aatggtttta
     3001 tgattggttg attttagata aacctactgc ttcagcattt ccagaaacaa taaaaagctt
     3061 cttctctcca gaggaattga actatatttt taaatcgaat gctaacaact ttgaaacagg
     3121 tgttagaaat gaaattaaaa ataatatcaa attcaaccca tttataaact ggtttaaaaa
     3181 gcgatataag gataaacgct attatgaaac tgatacccaa atttttgttc atgcaggcat
     3241 tgatgaagaa gcaggaatgc tttggaaaga actaacgagt tcaaagatat ttacaaacaa
     3301 atttccaatt accactggta gatttcataa agctattatt tcgggccata ttgcttcttg
     3361 ggaagtagct aaagataaaa cttatcaagg taagatttac tttgatggta aaaaccatta
     3421 cttcattgac ggcgatgtgt atcatagtaa aacaatacct gttatctgct atgatacagt
     3481 tacaaaatcc tatcaatatt aaataacatc ctaaaaaaat tggcagaatt taactctatt
     3541 cttagactaa tatcaaaaat aaagagggga atctatatga agacattatt aattggcgac
     3601 ttacatttaa aatctcaact aattttaccc attattgaca agattatcca aacacataat
     3661 attaaaagag tgatttttct tggtgattat gttgacttac atggacaaac taacaatatc
     3721 caactatatg ccaaagatct cactttttta tactcttgga aaatagataa agagcaaaac
     3781 ggaatagagg taattaatct tataggtaat catgatgctt attatttact gggagatcaa
     3841 gctcctttct caattcaaaa tttagaagtg tttttcgcag ttcaaggatt gttgcaggat
     3901 ttaaaattac aagtggctta tcaactagat gattatttag tcagtcacgc tggtttcaat
     3961 caaatatttg atcctcaaaa atggcatttt ttcccctata ccaaagagca tgaagaagaa
     4021 ttagatattc tagcttatac aataggacca atgcgtggtg gggaagctct tgggggttct
     4081 cctttatggg cacattttag agaattagaa ctgcttccca accaagactt tcctaaacaa
     4141 attgttggac atactccaaa agaatctatt gatatttcta aaaatattat tggtatagat
     4201 actttttcat tatatattga caaagataat aaatatcaat ttattggtaa cggagatttg
     4261 ctagtttatg accaaggaca tcttgaaatc atttcaactg actgggctac agaccaaaca
     4321 ttaaaacaat tacctaaacc tcaaatttaa ctactacttc tcatcatgct actaagcgaa
     4381 actgccgact ggaagtcggc aagctggaag cgtgtttagc agagcgatgc ttagaaacac
     4441 atgatagaag tatggaggag ctttgcttct cctagtttat ttattatata agcaaacatt
     4501 acgagaaaag gagatgattt tgtgagttac aatcgcaaaa ttatccgaac ttcttcgtac
     4561 cttgaaatat gggaatacga atctccaatt ttttcaaatg atactactca aattgatgaa
     4621 gaacatattt cactaaaaga aaagaagaaa cgtagaactt ttgaagaact cacaactgct
     4681 gaacaagatg aacgaataaa aagaatttct aacactcgta aaaattctaa atggaaactt
     4741 caacgcctaa tagatacaaa ttttgatgac agaactagtt tccttaccct tacaaccaaa
     4801 gaaaatatac aaaacagata tgagtttaat ttactttttg ataaatttat taaacgttta
     4861 aactatcaca tataccattc caaaaaaaga cttattaaat atattgcagt attagaacga
     4921 caaaaaaggg gagcgtggca tgcacacatt ctcctttttt catttccttt tatccctcat
     4981 aaagaattac tgacaatttg ggggttaggt gcagttcgga taaacaaact aaataagtta
     5041 gatgattctt ctaatgctgg tcgttatgtt gcaaaatata tggaaaaagg cataggacag
     5101 gaattattag agagtctagg aaagaaggct ttttattctt ctcgtaattt acaaaagcct
     5161 gaagaaataa aattatttac aagtgaatcc ttagataacc ttgttaagaa tgaagatatc
     5221 ctatatgaaa gcaactatat tagcaaagta tttcgaaaag gacacttaat tgacaataaa
     5281 gtaaaataca aaaaaataaa gttaagtaag gagtaaggaa aaaatgcaag ttattctacc
     5341 aacagaacaa gttcaagaaa tacagtcgat gattactaat ctcttgcaaa atgaaatttc
     5401 tcatttcaaa gaagatttag gtttagatag tccttacctt aacaaggggc aaacttgcaa
     5461 atatctaggg atatctaaca atacattaga tggctggata caaaaggggc tacccgttat
     5521 taaaattggt aagactgtcc gtttcaataa aaatgagatt gataaatggc tttgtagaaa
     5581 agctatgcta taatatctct aatgatatat cctgactcgt aaaaggagaa catcatgaca
     5641 gttacaaaaa caaatagtaa cacttacaat cttaaagtgt atatacctaa agaaatccga
     5701 cctaaaatgg ggattaaagg aaatcacttt gttaaacgct ataaaacaag aaaggaggcc
     5761 aaagaagctg aactagaaat tttaactaag atacatcaac ttgaaaatgg tgaggatatc
     5821 ctactttcta aaactaacga tattctattc tctgagttct ttaataatat ttggtgggat
     5881 tcatacaaag ctggtcaaac aacttcaaca actaaacccc caacacaagt tactattgat
     5941 aatactaaaa ctgttttcag aaagcatatc ttaccaatgt tcggtaatta ttcaatcaat
     6001 tttctgaatc agaataagca agtcgtacta aacttaatga ctgctaaagc tgaagagtat
     6061 gctaatttca aggttattcg aagctatgta aactcaattt tcgattgggc tgaggaatta
     6121 gagtacatag aatcaaatcg attatccaag acaattaagc gaattaaagc taccaaaaag
     6181 ctaaaactcc aagactccaa aaatgaggaa gacctgtatc tatctagtga agaattacaa
     6241 gattggtttg atgcttttag agaagattta gagaacgata aattatcact aaaagattat
     6301 gtcctattct ttacaacctt tattttgagc gatagaaaat cagaatccta tgctctacat
     6361 tggaaaaata tagacttggc aaatgctcaa attgacttaa ggcatgcact tgacaaatat
     6421 aaaaatgtga agtcaacaaa aggaaataag aaaacgattt tttcaattcc tagttacctt
     6481 gtatcacttc tttcagaatg gaaaaaacaa cagaaatatg agttagcgaa atttggtata
     6541 atgcaaacat ccgatcaact agtctttacc tatatagata cgaaaggtaa tgtaaatagc
     6601 cctctacacg ttgattatct taataacaaa atgaactccg taaaaagacg gcacccaaag
     6661 ttaaaacacg ccacacctca taaattacga catacaggag cgacacttgc taaaaaggca
     6721 ggaatgagct tagaagccat ttctgaagca ttaactcata gtgatacaat tacaactaaa
     6781 acttatgtta atgcttcaaa catagttcca ttatctgctg gacaagttgc ctaccaacat
     6841 cttaaaaaca agtagggtaa ttttagggca aattttaggg caaacttttt tagaaagtat
     6901 agaaaaaagc acccataggg caaacctttg agtgctttga aacattgata taatcgtatt
     6961 gattaacgtt ttgagaactg gctagcttta cgagctttct taagacctgg tttcttacgt
     7021 tcaactttac gtgagtcacg tgtaagaagt cctgcgcgtt tcaatgaatc gcggaagtct
     7081 gggtctactt gaagaagggc acgagcgata ccgtgacgga tagctcctga ttgaccagcg
     7141 tatccaccac ctacaacgtt aacgaaaacg tcgtatgaac ctacagttga agtaactgcg
     7201 aatggttggt tgatgacaag acgaaggtca gcgtgtggga tgtactcttc aacatctttt
     7261 ttgttaacag tgattttacc agttcctgga acaaggcgaa cgcgtgcaac agcgttttta
     7321 cgacgtccag tacctgcata ttgtgcttgt gacatacttt attgttcctt tccttagata
     7381 agttctgaaa tgtcaagaac ttctggttgt tgtgcagcgt gagtgtgctc agctccaaca
     7441 aatactttca acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta
     7501 actgatttct caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt
     7561 ttcaatccac ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca
     7621 gtcaatttaa ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt
     7681 gtaaatgttg gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca
     7741 agtggtacat cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc
     7801 ataaatgttg ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat
     7861 gggtgttcct tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa
     7921 caataccgcc tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat
     7981 ttttcggtaa cttctcaaag taactgaaag ttatataatc aagttaattt gggaatttac
     8041 ctattaactt cggtagattt ttgggaattt ttttccttct ttttccctgt agttaaaatc
     8101 cttttcaaaa aatcaccttt tcttgatttt taatcctatt tgctgtatga taagggaaaa
     8161 gaaaggggac agagatatgg cttttaccaa tacccacatg cggtctgcta gttttggcat
     8221 tgttaccagc ttgcccgatg acatcattga ctctttttgg tatatcatcg atcatttctt
     8281 aaaaaatgtc tttgaattgg aagaagaact cgagtttcaa ttgcttaata accaaggaaa
     8341 gattaccttc cacttttcaa gtcaacacct ccctacagcc attgattttg actttaacca
     8401 tcctttcgac cctcgttatc ccccaagagt actggtttta gacatggacg gtagagaaac
     8461 tatcctcctc ccagaagaaa atgacctatt ttaatactca atgaaaatca aagagcaaac
     8521 taggaagcta accgcaagct gtacttgagt acggtaaggc gacgctgacg tggtttgaat
     8581 ttgattttcg aagagtataa aaactctagc cttcagttgc aagtgactga aaactagagt
     8641 ttttctattt tttcaaagca tcacacaagt tgcggatcgg ttgttttaat atcggatgga
     8701 taaaatgagg cgcaatttcc tgtaaggact caaggacaaa aaggcgttcc gctatgtaag
     8761 gatgaggcaa tatgaggtcg tctgtataaa ggatctggtc ctccacaaag agcaagtcca
     8821 aatcaatcaa acgagggccc caatgcactt ctctcacccg tcccagctct gactcaatgg
     8881 ctaacaaggt ttctaacaag tcttgtgctg gtagccaggt ttccacctca accacttgat
     8941 tggcaaagct atcctgctcc actccacccc aaggctccgt cgctaagaca ctggactctt
     9001 tgagaatatg gatacctcga tttcgcattt tctcaatggc ttgtttcaag tttgcttgtt
     9061 tatctcccat attgcttcct agggcgataa aggctcgttg cttgcggcga tggatggtta
     9121 ccgagcaagt atctagtgac aaatgcaccg gtgcccaagg ttttttcagt tccaacttca
     9181 tttcttggac aagaggataa gactcaaagg tacgttccac cagtttatag gctaccgttt
     9241 caatcaaatc ttcactcgtt tcctgaaacc aagtcgtcca ctgctgacac aattctccgt
     9301 aatggacaga ggctgttaaa tccaagtctg tagctgcctt ggtcatatca taggatagga
     9361 tggctgaaac gacaaatttc tgccccaatt ctttctcact aggaaaaaga ccatgatagg
     9421 caaacatttc caaatcctta atctgcagtt gatccataat gattcctttc tagaaaaatc
     9481 cgcttgaagc ggattctttt tatagcccca ttaaacgata agcttggtcg cggaggtcct
     9541 tatctgtttc aaatagacca cgagctactg tcgtcaaggt tgcagtgcct ggttttctaa
     9601 caccacgcat actcatacac atatgttccg cctcaatgac aacaaaggct cctttagcac
     9661 ctagatagtc catcaaggca tcggccactt cgatattcaa acgttcttga atttgtggtt
     9721 ttttcgaata aacttcaacc gtacgggcta gcttagacaa gcctgccaca cgaccatctg
     9781 gaatgtaggc aatgtgcgct ctaccataaa atggcaagaa gtggtgttca cacatggtat
     9841 ggaaaaagat atccttttct accaccatat tatcgtcaat aatttcaaag gattttgaca
     9901 aatgttcctc tgctgtttga ccaagacctg aaaaaatctc ttgatacata cgggctacac
     9961 gagcaggtgt ttcctgcaag ccctcgcgat tagcgttctc tcctacagcc tcgataatca
    10021 tttttacagc tgcttcaatc ttttgtgtat ccattctcgt tcttcctctc catcagatag
    10081 gccctcactt ggctcaagaa atacaaggaa cctgtgacaa tcctaactgt ttgtttctct
    10141 tcttttttat ctgtcacatt ctgctctaga aaatcatgcc aatcttggta gctgagattt
    10201 ctagacttag ctgcctcttt cagcacgctt tcatccgtcg cccgactatc cgcaaaatgt
    10261 gttagagtaa gctcggtatc tggcatggct cccagcaagt ccaacatatc ctccaaggct
    10321 ttggttttga tacaagtgaa gaggatttcc ttatgataat ccgcaaaacg ttcttgcaag
    10381 gttaccaaca aggccttgat agcatgggga ttatgggctc catccaaaat catcaaggga
    10441 tctcttgaca cgatttccaa acgccctggc caacttgttt cttccaaggc ttgaccaaga
    10501 aagtcattgc ttgctagctc tcgaccatct tcttgacaaa aagtatcaag taaagctatg
    10561 gccatcccag cattctctat ttggtacaaa ccaagcaggc tagtctggaa gcgaccttgt
    10621 ctgacagcac ttgtatagtc aaagacttcc cctgtcacca cactttcttg atgacgaacc
    10681 tgataatctg tcccgtaggc aagtctcggc gcatctttcc cttccgcaat gcggtcaatc
    10741 acagtcaagg cttctggagc aatacgccct gttaccaagg gcatcccttg tttgataata
    10801 cctgccttct gctctgctat ggcctccaag gtgtcaccaa gtagggccac atgatccaag
    10861 ccaatagttg taattcctgt caaaatgggc tgacagacat tggtactatc caaaagtcca
    10921 cccatgccaa cttccatgat ggccacatct acttgctctg aggcaaagta gtcataggcc
    10981 agggctgtga taatctcaaa ctcggttgtg ccctgtaaat tggcgaccgc ttctccctcc
    11041 agcaaagact gatagtctgc catgagagct tctagcctcg cttctgagat cgattcccca
    11101 ttgatgctaa tctggtctgt gtaatgaatg agatagggcg agctaaacac gccaactctc
    11161 agccctagct tttctagcat ctttttcaaa aaagcaatag tcgagccctt gccgttagtc
    11221 cctccgatat ggaggacctt gagtttgaga tggggattgc cacgcaaagc taacagttcc
    11281 accattcgtt ccaatccaaa atgcggttga tccgtccggt agttagcaat ccactgattg
    11341 ttttcaattt ctttcatctt atttatattg ttttaaatct aaattttccg cttcatcagc
    11401 cagacgaatg gcagaggcaa tttcaactgc catcctgtga ctagctacgt catgcacgcg
    11461 caccacttct acaccctgtc tcgcagcgat actagttaca tgagccgaag ccgtgtcccg
    11521 atttcggaaa ccaagctctg tctcaggatt gacttcaaaa ccattctcct ctaggatatt
    11581 gatgacaaat cgcttgcgcg acactccgag aaagattgga tagcccttct gatgtagttt
    11641 atccaggtcc cgtaaaagaa gcagattttc tttcttggtc agaccaaagc caattcctgg
    11701 atccaacagg atattttctg gtgcaatacc agcttctgcc gctctcgcta gtgctcgttc
    11761 aaagaaagcc tccatcaatt cttcgattgg caatgtttca aagtcagcta actcttcctc
    11821 tgtaaaagct tgaccaaaac caaaatgagg gaagatgagc gagctagggt gctgaggtcg
    11881 cgccataact ggattaaaca tgatgaccac ttgcgctctc gcttcagcta ccacatgagc
    11941 cattttctca tcacccataa gaccagtgat atcattgact agatcggcac cagcagccaa
    12001 agcagcctct gctacttgac tcttccaagt atcaatagag atgaggacat cactttcctt
    12061 gcgaatcgct ttgatcactg gaacaacacg ctggatttcc tcttctatct caacatagct
    12121 actgcccggc cgagtcgatt ctccgccgat atcgagcata ctggctcctt ctgctatcaa
    12181 tttacgagcc tgctggagtg cctgctcaag agcaaaaaat ttaccaccgt ccgaaaagga
    12241 gtctggggtt acattgataa ttccgcaaat aactgtcttt gcatgattgg ctttacttga
    12301 catatcggtc actccctcaa ggattttcat catattattt ttctatttta ccataaaaag
    12361 aaaaagatgg acacgattgc attcatcttt ccctagtaga aagaggtcgg ttcctacata
    12421 aaaactttta cacagaaatt cctaatgtcc gactcataat caccacaaga gccaacaaac
    12481 agaaagcaat cccattaaca atcatgtgaa gcaagatcga catttccaaa cgttgggtct
    12541 tgtaggccgt ccaagataga actgtcgaca tacctccata aatcaataaa gaaggtaaat
    12601 tacttggttg atgcaataaa gcaaacacaa tcgtaccgac tacaaatccc aagttctcct
    12661 tgcctcggaa aatcttttta ggaacaagcc cacggcacaa gatttcctca caaattggag
    12721 caagcaaggc tagcaagaag aagctagaaa tcagagaact attctgaacc atatcgttaa
    12781 tctgagactg gttagctgtt gtcgtctcat ttgacagttg caacaagata gaaccaagta
    12841 tatttgaccc gacaataact aaataactca agcccaaacg tgccaaatct ttagctctaa
    12901 aaaaagaaaa attaaaacta gctaacttgg ttttacgagc tcccataata aatagagcca
    12961 gaaccacaat tgaaaggcca gcaactatca gccctgactg tagcagggct acttctttta
    13021 aagtcaaaat agaggtaacc actaggggaa cctgatataa aaggacggca agtaaaaaga
    13081 ccaaaatcca gcctgcacga ttcaacaatt ctttccacat atttttctct ttcatcacct
    13141 atctcctttg tattaaaaaa gggggaaaat ccccctgggt cattctatta taaggccatg
    13201 ctgatgtagt taaggataaa caaggcatcc aaaatccaaa tcatggcatg aacatcttta
    13261 acttgacctt tgacaagctt agtcaaagtg taagtcaaga aaccaactgc aatcccttga
    13321 gtgatagagt agctgaatcc cataaagata gatgtgaaga aggcaggaac tgcttcagac
    13381 atatcatccc aatggatatt tttcaagcta ccaagcatca taatcccaac gataatcaag
    13441 attggagctg tagccgctgt tggtacgatc gctagaagtg ggctaaagaa gcttgaaatc
    13501 gcaaaacaga tagctacaac caaggctgtc aaaccagtac gtccacctgc accgatacca
    13561 gcagcagact caacataagt cgttacgttt gaagtacctg caatggcacc gactgtcgtt
    13621 ccaatcaaat cagagtaaag agccttatcc aatttggctg attggtgatt ttcaccattt
    13681 gtcgctacaa taccaacttt ttcacctgta ccgatcaagg taccaattgt gtcaaaaata
    13741 tctgtcaatg agaaggcaag aatggccatc agagtttcag gcaagcgagc tgtatctgaa
    13801 accaaagctc ccaaaccttc tgaaccaaga gctgcaccaa agattgtctt caaatcttca
    13861 aaagctgcac caacatggtt attagcaaaa tcgatactag acaaatcaac caaaccaact
    13921 gcaatagcaa gaacagttgt tgtcaagata gagagaataa ttcccccttt aatccctttg
    13981 atgacaaaga agatagtaat ggcaagtcct gcaagagcca ctaaaacagc tggattatta
    14041 aagctgacca atcctggaac tgctgaagag tttgctgcaa tcgttgcttg agctttgtca
    14101 gccccttctc ctacaacagt atagttgcct ggatcaatcg tgaatttcaa aagtccagca
    14161 ttcttaatcc ctacataggc aaggaagaca ccgataccag ctgaaatagc tgagcgaaga
    14221 gcattgggaa tcgattcaat gatcatttta cgaacatttg tcaaggtaat aatcaatgaa
    14281 ataatcccac agatgaagac catagctagg gcttcttgcc aagaataacc aagcccgaat
    14341 acaactgtaa aggtaaagaa ggcattgagt cccatacctg gcgcttgggc ataaggtaag
    14401 ttagcataaa aagccatcat caaggtaccc gctactgcac caataatcgt cgctaggaag
    14461 acgccctgag caggcattcc tgtttgtgaa agtatttgtg ggtttacaaa gagaatatag
    14521 ctcattgcaa agaaagttgt taaaccagcg agaacctctg tacgaacgtc tgtaccgttc
    14581 tcttttagtt taaataattt gtccatcatc aatctccttt taatttttac gaacaataat
    14641 agaattatat catttattat tcactttttc aatgtctttg tttgatttgt ttaagaaatt
    14701 aatccaattt cattttttgt ttggaatctg cttttctgcc tgctttctgt tataatagaa
    14761 gacatcttat ctgaaaacac actagaaagg tccatatgac gaaaaaaatt attgcagttg
    14821 acctggatgg aaccctgctc aactcagaca gtcaaatttc tgactttacc aaaaaaacca
    14881 tcaaaaaagt tgctgaaaaa ggccatcagg ttattattac gacaggtcgc ccttaccgta
    14941 tgtcaaaaga tttttaccgt gaactgggct tagacactcc tatgattaac ttcaacggat
    15001 cccttactca tttaccagac caagtttggg attttgaaaa gtgtttgact gtagacaaaa
    15061 aatatctgct agatatggtt caacgttcag aggacattca agccgatttt atcgctggag
    15121 aatatcgtaa aaaattctac attacaaatc ccaatgaaga aattgccaat cccaaactat
    15181 ttggtgtaga agttttccag cctgaagatc aattccagcc tgaattggtg accaaggacc
    15241 ctaactgtat cctcttgcag accagagcca gtgacaaata tgccttggca aaagacatga
    15301 acgccttcta ccagcatcaa ctttctatca atacctgggg aggtccgctc aatatccttg
    15361 aatgtacccc aaaaggtgtc aacaaggcct ttgctttgga ctacttgctc aagataatga
    15421 atcgtgacaa aaaagatttg attgcctttg gagatgaaca caatgatacc gaaatgctcg
    15481 cttttgctgg gaagggttat gccatgaaaa atgccaatcc agagctactc ccttatgcag
    15541 atgagcaaat ttcccttacc aacgaccaag atggggttgc caaaacccta caagacttat
    15601 tcttataacc tatactgata ctcaatgaga atcaaagagc aaactaggaa gctagccgta
    15661 ggttgctcaa agcactgctt tgaggttgta gatgaagctg acgtggtttg aagagatttt
    15721 cgaagagtat gaccagcttg caagctggtc tttgtgctct tttcacagtc tcatcaacca
    15781 gttaatcgat tgttctactt tttgtctcca aaaccttgga aaaggctttc ttttgtgata
    15841 tacttcacat ataaatacaa gagagctcgt cacactcgac tctgttgaca aaaaatcaat
    15901 ccagtcccgt tgtccctgtt ctcggtcaat atcaaggagg atagctatga aagctgttgt
    15961 tgtaaatcca gaaagcactg gtgttgctat tgaagaaaaa gtactccgtc cacttgaaac
    16021 tggggaagca cttgtagaag ttgaatactg tggcgtttgc cacaccgacc tccacgttgc
    16081 tcatggtgac tttggtcaag tcccaggacg tgttcttggg cacgaaggta tcggtatcgt
    16141 taaagagatt gctccagatg tgaaaagcct taaagtcggt gaccgcgtca gcgttgcttg
    16201 gttctttgaa ggatgtggca cttgcgaata ctgtacaact ggtcgcgaaa ccctttgccg
    16261 tacagtgaaa aatgctggct actcagtaga cggtggtatg gctgaacaat gtatcgtaac
    16321 tgctgactat gctgtcaagg ttcctgacgg acttgatcca gcccaagctt cttctatcac
    16381 atgtgctgga gtaacaacct ataaagctat caaagaagca aaagttgaac caggccaatg
    16441 ggttgttctt tacggtgctg gtggacttgg taacctcgct gttcaatacg ctaaaaaagt
    16501 attcaatgct catgttatcg cagtcgatat caacaatgac aaacttgccc ttgcaaaaga
    16561 agtaggcgct gacattgtga ttaacggcct cgaagttgaa gatgtagctg gactcatcaa
    16621 agaaaaaact gatggaggag ctcattcagc tgtcgtaact gctgtgtcta aagttgcctt
    16681 caaccaggct gttgactccg ttcgtgctgg tggtcgcgtc gtcgctgttg gtcttccttc
    16741 tgaaatgatg gaactcagca tcgttaaaac agtcctcgat ggaatccaag tcatcggttc
    16801 tcttgtcgga actcgtaaag acttagaaga agccttccaa tttggtgcag aaggtctggt
    16861 agccccagtt gttcaaaaac gtccagtaga agatgctgtt gccattttcg acgaaatgga
    16921 aaaaggtcaa atccaaggac gtatggtact cgacttcacc cactaatcta atagaaacct
    16981 attttaaaag ttggaagctt cttccaactt ttttatatta aatttttaaa taagaattca
    17041 agattactcc tcaaaaactc aacatatcaa catacaaaaa taaaaatttt ttaatttttt
    17101 atgataaata gttgcttttt ttatgaaaac ggtttatact taaacagtct taaagttttc
    17161 ttaaatgaaa actaaaacaa aaaaggagga atgacaataa tgagtatcgg aatcattatt
    17221 gcgagccacg gcgaatttgc tgcgggtatt catcagtcag gatctatgat ctttggtgaa
    17281 caagaaaagg ttcaagttgt gacctttatg ccaaatgaag gtcctgatga tctatacgct
    17341 aagtttaata acgctgttgc tgcatttgac gcagaagatg aggttctagt tttggctgac
    17401 ctttggagtg gttctccatt taaccaagct agtcgcgtaa tgggagaaaa tcctgagcgt
    17461 aagtttgcca tcatcacagg acttaactta ccgatgttga ttcaagccta cacagagcgc
    17521 ctcatggacg ctgctgcagg tgtagaaaaa gtcgctgcta atatcattaa agaagccaaa
    17581 gatggcatca aagctcttcc agaagagcta aatccagttg aagaagttgc aagcgctgca
    17641 gctgctccag ttgcccaaac tgctatccca gaaggaactg ttatcggaga cggtaaattg
    17701 aaaatcaatc ttgcccgtct tgacacacgt ctacttcacg gtcaggttgc aactgcttgg
    17761 actccagatt caaaagcaaa tcgtatcatc gttgcttcag ataacgtggc taaagacgac
    17821 cttcgtaaag aattgattaa acaagcagct ccaggtaatg tcaaggctaa cgtggttcca
    17881 attcaaaaac tgattgagat ttcaaaagac ccacgttttg gagaaacaca tgcccttatc
    17941 ttgtttgaaa cacctcaaga tgcccttcgt gccatcgaag gcggcgtgcc aatcaagact
    18001 cttaacgttg gttctatggc tcactcaaca ggtaaaacat tggtcaatac cgttttgtct
    18061 atggacaaag aagatgttgc tacatttgaa aaaatgcgtg acttgggtgt tgaatttgat
    18121 gtccgtaaag taccaaatga ttctaaaaaa gatttgtttg acttgattaa caaagccaat
    18181 gtcaaataag ccattattta tgaaaggatt ttaaacatgt ctattatttc tatggtttta
    18241 gtagtcgttg tagccttctt tgcaggtctt gaaggcatcc tcgaccagtt ccaatttcac
    18301 caaccacttg tagcctgtac ccttattggg cttgtaacag gtcacttgga agcagggatt
    18361 atcctcggtg gatcgcttca aatgattgcc cttggttggt caaatatcgg tgctgctatc
    18421 gctcctgatg ctgcacttgc ttctgtcgct gctgccatta tcatggttct tggtggtgac
    18481 tttaccaaga ctggtatcgg tgttgcccaa gcggttgcta tccctcttgc cgtagctgga
    18541 cttttcttga caatgattgt tcgtacaatt tcagttggtt tggttcatac tgcagatgct
    18601 gccgctaaaa aaggtgactt cggcgctgtg gagcgtgcgc atttcattgc gctactcttc
    18661 caaggacttc gtatcgcgct tcctgcagct cttctcctta tggtaccaac tgaaactgta
    18721 caaagtatcc ttagtgccat gccagactgg ctcaaagatg gtatggctat cggtggtggt
    18781 atggtcgttg ccgttggtta cgccatggtt atcaacatga tggcaactcg tgaagtatgg
    18841 ccattcttcg ctcttggttt cgttctcgct gctgtgtcag atattactct aatcggattc
    18901 ggtgctatcg gtgttgctat cgctcttatc taccttcacc tttctaaaac tggtggaaat
    18961 ggtggcggag gagccgcaac ttctaacgac ccaatcggcg atatcctaga agactactaa
    19021 gataagaaag gactgaaaac atcatgactg aaaaacttca attaactaaa tcagatcgta
    19081 aaaaagtttg gtggcgttca accttcttac aagggtcttg gaactttgaa cggatgcaaa
    19141 acttgggctg ggcttataca ctcattccag ctatcaaaaa actctatact aaaaaagaag
    19201 atcaaatcgc tgctcttgag cgtcaccttg agttcttcaa cactcatcca tacgtagctg
    19261 ctccagtcat gggggttact cttgcgcttg aagaagaacg tgctaacggt gtggaaatcg
    19321 atgacgctgc tatccaaggg gttaaaatcg gtatgatggg acctcttgct ggtatcggtg
    19381 acccagtatt ctggtttaca gtacgcccaa tccttggatc tctcggtgct tcacttgccc
    19441 ttactggcaa tatcttgggg ccactcctct tctttgttgc atggaacttg attcgtatgt
    19501 cattcttgtg gtatgttcaa gagattggat acaaggctgg atcagaaatc actaaagata
    19561 tgtctggtgg tatccttcaa gatatcacta aaggagcttc tatccttggg atgttcattc
    19621 ttgctgtcct tgttcaacgt tgggtaaata ttaaatttgc tttcgatgtt tctaaagttc
    19681 aactagatga aaaggcttat atccattggg ataaattgcc agaagggtct aaaggtatcc
    19741 aagaagcatt cgcacaagta ggacaaggat tgtctcaaac tcctgaaaaa gttactactt
    19801 tccaacaaaa cttggatatg ttgattcctg gattatcagg actactcctt actttacttt
    19861 gcatgtactt acttaagaaa aaagtatctc caatcactat tatccttgcc ctcttcgcag
    19921 tgggtattgt ggcacatgtt cttcacatca tgtaatcaag caactaaaaa ggaaccaggt
    19981 tctaaaatct gattcctttt ttctatgctt ttattcagcc aaggctccca ttggatccca
    20041 tggtgcaagt acgattggtt ctgctccata ggcagcttgt tcttctgctg tcagcaattc
    20101 cttacgaaca acgatttggt atgtgtattc gtccatccaa gcgtctgagg caacaaagta
    20161 accatctgta ccgaccttgt ctccccatga gttttcaacc ttccacttgg ttgatttacc
    20221 attttcgtcc aagtcaacac ctgtcaagac catggcgtgg gtcatcaagc tttcgctata
    20281 gtccaaacgt ccagccttgt cttgagtaag tttaatgtcc atgcttgatt caaagtcata
    20341 aacatctgtc gcaaggatgc cagccttacg gttgctgagc tggccgacat cagaaccaaa
    20401 ccaaacagtc tcacctgctt gcatttgggc aatcgccaat tctttcaagc gctccattgg
    20461 aacgttgatg tagcgaactg cacggctacc aaccacattc cccaacatct caactgtgta
    20521 agattttccg taaggtttat cagcagttgg agcattgata acagaaacgt agtcttctaa
    20581 aggaagattg acatatttct tgtaaaactc ttgtggtgtg attccttttt cacttttata
    20641 gttgttatct ttatcgcgat aagcaaagtc aaacttgcgt ggtggaagtc ctaatgacat
    20701 agcaagaaag ttaaagattt cttgcaagag gtcttctttc ttagcttgaa cagtcgcttg
    20761 atctgcacca gaaacaagca aatcacgcaa gatttgagca tcttgacgaa gcaatttatt
    20821 aaggatcgca tttagctcac gactgctgct agatgaaaca gactcaggat aaactgactt
    20881 aggcacgaca ccgtattttt caaagaggga aacgaccata tcccattgac cgccatcttg
    20941 ttgaggtgtt tggagtaaga agctaacctt gcggctagtc aattcttggt ctgaagtcgc
    21001 aatgacttgc tccaagaacc agtttgattt ctcatactta tcccagaaga aagtgtgggc
    21061 ttgtgacaac tcaaagttct ccaatttgta ttgcgagatg agtttgtggc ggaaggtgtt
    21121 gagagccgca aacatccagc aacgaccaga cgctttctgg ttagtgacct tgtccttggt
    21181 taaatccaat gagaaaacag gtgtgttgtc tacatggctt tggcgacatt ccagagctgc
    21241 aaaaattccg ttgtggctgg cagcattttc aatcgcttgg tattttacat ttgcttcata
    21301 gttggcaaat agtttatcag taaatgattc ttgaatcgcg ttcatagatt cctcctttta
    21361 ttctacagtc tattataact cttttcacaa aggaagcaac taaaaaacat aaaaggcgag
    21421 gacattgtcc ctcacctttt tcgaatttat actcttcgaa aatcaaattc aaaccacgtc
    21481 aacgtcgcct tgccgtactc aagtacagcc tgcggctagt ttcctagttt gctctttgat
    21541 tttcattgag tattaaacta aattaaataa tattagcgcg gagaatttct aattcttcct
    21601 tggtcaagcg acgccattcc cctcgttcca ggttctcatc taatactaaa gttcccatag
    21661 tcaatcgttg caagtccacc acttccttgc cacagtagcc caccatacgc ttgatctgat
    21721 gaaacttccc ttctgcaatg gtcacacgga tttggctttg attcttttct gtatctatgg
    21781 atacaagctc cagtatagcg ggttgacagg taaagtcttt gagaggaata ccctcagcaa
    21841 atgtctccac atcttcttgg gtcatgattc ccttgacttg tgccagataa gtcttgtcca
    21901 catgacgctt gggcgaaaga agaacatgag ccagctgacc atcattggtc aaaagcaaaa
    21961 gaccatgcgt gtcaatatcc aagcgtccta ctgggaaaac ttccttactc cgcgccaagt
    22021 catccaacaa gtccagaacg gttctgtgct tgggatcctc agtcgctgag ataactcctt
    22081 tgggcttgtt catcatgtag tagacaaact cttcatactc caacacttgc ccatcaaagc
    22141 gaatctcatc tattttttca tcaatctgca atttagctga tttttctttt ttaccattta
    22201 cagtcactcg cccagccttg agcaagtttt tgacctcagt ccgacttccc accgcacagg
    22261 caactaaaaa tttatctaat ctcatagaac t
//
LOCUS       DBEJJE010000035        21927 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEJJE010000035 DBEJJE010000000
VERSION     DBEJJE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.35"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(242..529)
                     /locus_tag="ACL3F5_001409"
                     /pseudo
     CDS             complement(242..529)
                     /locus_tag="ACL3F5_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            511..1040
                     /locus_tag="ACL3F5_001410"
                     /pseudo
     CDS             511..1040
                     /locus_tag="ACL3F5_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1115..2035)
                     /gene="cysK"
                     /locus_tag="ACL3F5_001411"
     CDS             complement(1115..2035)
                     /gene="cysK"
                     /locus_tag="ACL3F5_001411"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0515193.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(2320..2955)
                     /locus_tag="ACL3F5_001412"
     CDS             complement(2320..2955)
                     /locus_tag="ACL3F5_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0515194.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYASSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            3011..4309
                     /locus_tag="ACL3F5_001413"
     CDS             3011..4309
                     /locus_tag="ACL3F5_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0515195.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            4306..4968
                     /locus_tag="ACL3F5_001414"
     CDS             4306..4968
                     /locus_tag="ACL3F5_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0515196.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            5048..5596
                     /gene="raiA"
                     /locus_tag="ACL3F5_001415"
     CDS             5048..5596
                     /gene="raiA"
                     /locus_tag="ACL3F5_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0515197.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5732..7705
                     /locus_tag="ACL3F5_001416"
     CDS             5732..7705
                     /locus_tag="ACL3F5_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0515198.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7702..8154
                     /gene="rplI"
                     /locus_tag="ACL3F5_001417"
     CDS             7702..8154
                     /gene="rplI"
                     /locus_tag="ACL3F5_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0515199.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            8198..9550
                     /gene="dnaB"
                     /locus_tag="ACL3F5_001418"
     CDS             8198..9550
                     /gene="dnaB"
                     /locus_tag="ACL3F5_001418"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0515200.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9552..9818
                     /locus_tag="ACL3F5_001419"
     CDS             9552..9818
                     /locus_tag="ACL3F5_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0515201.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9907..11253
                     /gene="cbpD"
                     /locus_tag="ACL3F5_001420"
     CDS             9907..11253
                     /gene="cbpD"
                     /locus_tag="ACL3F5_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0515202.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      11336..11438
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11509..11799
                     /locus_tag="ACL3F5_001421"
     CDS             11509..11799
                     /locus_tag="ACL3F5_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0515203.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11762..12520
                     /locus_tag="ACL3F5_001422"
     CDS             11762..12520
                     /locus_tag="ACL3F5_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515204.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            12559..13566
                     /locus_tag="ACL3F5_001423"
     CDS             12559..13566
                     /locus_tag="ACL3F5_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0515205.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13566..14294
                     /locus_tag="ACL3F5_001424"
     CDS             13566..14294
                     /locus_tag="ACL3F5_001424"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515206.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            14413..14871
                     /locus_tag="ACL3F5_001425"
     CDS             14413..14871
                     /locus_tag="ACL3F5_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0515207.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14873..17305
                     /locus_tag="ACL3F5_001426"
     CDS             14873..17305
                     /locus_tag="ACL3F5_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0515208.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADRQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            17626..18279
                     /gene="rr06"
                     /locus_tag="ACL3F5_001427"
     CDS             17626..18279
                     /gene="rr06"
                     /locus_tag="ACL3F5_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0515209.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18276..19607
                     /gene="hk06"
                     /locus_tag="ACL3F5_001428"
     CDS             18276..19607
                     /gene="hk06"
                     /locus_tag="ACL3F5_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0515210.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19702..20229
                     /locus_tag="ACL3F5_001429"
     CDS             19702..20229
                     /locus_tag="ACL3F5_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0515211.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDSMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGRMKG"
     gene            20309..>21927
                     /gene="pspC"
                     /locus_tag="ACL3F5_001430"
     CDS             20309..>21927
                     /gene="pspC"
                     /locus_tag="ACL3F5_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HGR0515212.1"
                     /translation="MFKSNYERKMCYSIRKFSIGVASVAVASLVMGSVVHATENEGTT
                     QAPTSSNRGNESQAEQRRELDLERDKVKKEVREYKEKKVKELYSKSTKSRHKKTVDIV
                     NKLQNINNEYLNKIIQSTSTYEELQKLMMESQSEVDKAVSEFEKDLSSSSSSGSSTEP
                     EASDTAKPNKPTELEKKVAEAQQKVEEAEKKAKDQKEEDYRNYPTITYKTLELEIAEF
                     DVKVKEAELELLKVKAKESRDEKKIKQAEAEVESKQAEATRLKKIKTDRKKAEEEAKL
                     KEAVEKNAATSEQGKPKRRVKRGALGEQATPDKKDYFEKDFRPAFNKNQQMVAIQESL
                     NKLDDETKTVPDGAKLTGEAGNAYNEVRDYAIKVVSENKKLLSQTAVTMDELAMQLTK
                     LNDAMSKLKEAKAKLVPEVKPQPENPEHQKPTTPAPDTKPIPQPEGKKPSVPDINQEK
                     EKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDEFKKQALSEIDNVNTKVEI
                     ENTVHKIFADMDAVVTKFKKGLTQDTPKEPD"
BASE COUNT         6912 a         3642 c         4919 g         6454 t
ORIGIN      
        1 ataagtacag aaaaggatgt caaagctctc gcacctgaac aagtagacta gcttatgaag
       61 ggcttttcta tcactccaaa aatatagtag atggaaacta gaatagtaca cctctgcttc
      121 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctatt cttatttcat
      181 tttactataa atccatcaga aagtcgtgat ttctattgaa atgaggactt tctttttaca
      241 ctcatctgct ttcaaaaagc attctagtcc gtctccgatt aacgatggac tttatcacca
      301 ccttctccag tccttgtatg acatcttcca aagttcgaaa ggctttattc ttaaatccac
      361 gtttacgaat ctctttccac acttgttcaa tggggttcat ctctggtgtg tatggaggaa
      421 taaatgcaaa gccaatatta gtcggaatct ttaaggtact tgatttatgc catatagcat
      481 tgtccataac gagtaaaaga taatcatctg gataagcttg tgaaatctcc tattcctaaa
      541 gcccctttag cgcataactt tggctcagct tctattatcg ctcacaccat ccatcagaag
      601 tttaatctga aggtacccaa ttatcgccaa gaagaagatt gggctaggat gggtttacca
      661 atcacacgta aggaaatctc taatcggcat atcaagacga gtcaatacta tttggagccc
      721 ctttataacc tcttgcgaga gagactattg actcagccct tacttcatgc ggatgaaact
      781 tcttataggg tgctagagag tgatagtcag ctgacttact attggacttt tttgtctggg
      841 aaagctgaga aacaagggat tacgctttac catcatgtcc taatcgattt gttcatatct
      901 tatttcaatc cattataaat agtgagaaat atctatccta tcttctagaa tgtcttccaa
      961 acgtggaaac tctcgtaaac aaagaggttt tagaggccta tttaccatgg actaaagttg
     1021 tacaagaaaa gtgcaaataa gaaatctcca gattaggaac tatccgtgag ttctctagtc
     1081 tggagatttt tcaatagact tcgttattgg acggttacaa ttcataaagt gctgtagaga
     1141 gataacgttc accgttatct ggtgctaggg caaggacttt tttacctgta cctaattttt
     1201 tggcaacctc gatggctccg tagatagctg cagctgagga aatccctaca aggaagcctt
     1261 cttttccacc aatttcacgt ccgagtgcaa gagcgtcatc tgatgttaca cgaacgatac
     1321 catcataggc tttagtatca agtgtatcag gaataaatcc agctgagata ccttgaattt
     1381 tgtgaggacc aggtttttca ccagatagaa tagcagattc atctgcttct actgcaaaaa
     1441 cttgaatgtt agaattttct gatttgagtg catgagaaac accagaaatc gttccaccag
     1501 tacctactcc agcaacaaag gcatctaatc catctttacc gaaagcagct agtatctcag
     1561 ctcctgttgt tctttcgtgt acttctggat tagctggatt gtcaaattga agaggaagga
     1621 aaccatcacg ttcagcagcg atttcttgag ccttagcaat agcacctttc attccctcgc
     1681 taccaggagt taggacgagt tcagcaccat aagcttggat aattttacgt cgttctacac
     1741 tcatagtttc aggcataacg atgacgactt tatacccttt agcagcacct acccatgaaa
     1801 gtccaatacc ggtgtttcca cttgttgctt caacaatagt agaaccaagt ttcagaatac
     1861 catcttgttc agctttttca atcatgctaa gggcaatacg gtcttttaca gatgaaccag
     1921 gattaaatgc ttcaagcttt atatagacgt ctgcagcacc ttctggcacg atgttgttaa
     1981 gtttaacaat cggtgtttga ccgattaatt cagtaatgtt gttataaata gacatatgaa
     2041 tacctctttg tataagatat ctttagtata acgctatcca taccatttgt aaaatataga
     2101 aatcctatcg aagcgatagg atttctatat atcatagatt aaagtcatta attttcaagt
     2161 gattgcgttc agttaattct agtaaatagg tgtgaaggaa aacgatatca ggtttcgttt
     2221 gaattgcttc attttctagt atattttggt acgcatcttt ttattttgct cgctaaagta
     2281 gttgtgagaa tgtcaacgaa acgctgtatt attcattgtt tacactaagt ttacaggaac
     2341 ttcaacctct cgtaaacctt ggtcagttaa agtgactttt ccattaaaaa actccacaag
     2401 tgcagcttta atagtttctt tttcttcttt atcaacataa atcatcgtat cgacttgatc
     2461 tgtaaagttt gtatccagct ccatgagatc atgttcttta aggaagttac tgtactcttg
     2521 gtactgagca taagacattt gaatagcaat gccagcctgt tcttttattt caataatacc
     2581 aatttctttg acagctaagg cgacactgct ggcgtaagca cgaattagtc ctccagcgcc
     2641 tagtttaata ccaccaaagt agcgtgtcac gaccacacag acattggtga gattgtgatt
     2701 ttctagtacc ccaagcatgg gaacaccagc agtaccacta ggctcaccat catcacttgt
     2761 acgtttaatt tcactacgtt ctccaataat aaaggcagag cagttatgtg tcgctttgta
     2821 gtgttctttt ttgatggcag taatgaagtc acgagcctct tcttcgctat aaacacgctt
     2881 ggcatggcag ataaagcgag attttttgat ttcttcttgg acttggccgt cctctttaat
     2941 tgtcctaaat tccatgattt aattgtacta aaaaatcatc taaagtgcta gtttttacga
     3001 ataaagaagt atgaaagtaa atttagatta tctcggtcgt ttatttactg agaatgaatt
     3061 aacagaagaa gaacgtcagt tggcggagaa acttccagca atgagaaagg agaaggggaa
     3121 acttttctgt caacgttgta atagtactat tctagaagaa tggtatttgc ccatcggtgc
     3181 ttactattgt cgagagtgct tgctgatgaa gcgagtcaga agtgatcaaa ctttatacta
     3241 ttttccgcag gaggattttc cgaagcaaga tgttctcaaa tggcgcggcc aattaactcc
     3301 ttttcaagag aaggtgtcag agggactgct tcaagcagta gacaagcaaa agccaacctt
     3361 agttcatgcg gtaacaggag ctggaaagac agaaatgatt tatcaagtag tggctaaagt
     3421 gatcaatgcg ggtggtgcag tgtgtttggc tagtcctcgc atagatgttt gtttggagct
     3481 gtacaagcgc ctgcaacagg atttttcttg cgggatagct ttgctacatg gagaatcgga
     3541 accttatttt cgaacaccac tagttgttgc aacaacccat cagttattga agttttatca
     3601 agcttttgat ttgctgatag tggatgaagt agatgctttt ccttatgttg ataatcccac
     3661 gctttaccat gctgtcaaga atagtgtaaa ggagaatgga ttgagaatct ttttaacagc
     3721 gacttcgacc aatgagttag ataaaaaggt ccgtttagga gaactaaaaa gactgaattt
     3781 accgagacgg tttcatggaa atccgttgat tattccaaaa ccaatttggt tatcggattt
     3841 taatcgctac ttagacaaga atcgtttgtc accaaagtta aagtcctata ttgagaagca
     3901 gagaaagaca gcttatccgt tactcatttt tgcttcagaa attaagaaag gggagcagtt
     3961 agaagaaatc ttacaggagc aatttccaaa tgagaaaatt ggctttgtat cttctgtaac
     4021 agaggatcga ttagagcaag tacaagcttt tcgagatgga gaactgacaa tacttatcag
     4081 tacgacaatc ttggagcgtg gagttacctt cccttgtgtg gatgttttcg tagtagaagc
     4141 caatcatcgt ttgtttacca agtctagttt gattcagatt ggtggacgag ttggacgaag
     4201 catggataga ccgacaggag atttgctttt cttccatgat gggttaaatg cttcaatcaa
     4261 gaaggcgatt aaggaaattc agatgatgaa taaggaggct ggtctatgaa gtgcttgtta
     4321 tgtgggcaga ctatgaagac tgttttaact tttagtagtc tcttacttct gaggaatgat
     4381 gactcttgtc tttgttcaga ctgtgattct acttttgaaa gaattgggga agagaactgt
     4441 ccaaattgta tgaaaacaga gttgtcaaca aagtgtcaag attgtcaatt ttggtgtaaa
     4501 gaaggagttg gagtcagtca tagagcgatt tttacttaca atcaagctat gaaggatttt
     4561 ttcagtcggt ataagtttga tggagacttc ctgttaagaa aagttttcgc ttcattttta
     4621 agtgaggagt tgaaaaagta caaagagtat caatttgttg taattcccct aagtcctgat
     4681 agatatgcta atagaggatt taatcaggtt gagggcttgg tagaggcagc aggctttgag
     4741 tatctggatt tattagagaa aagagaagag agagccagtt cttctaaaaa tcgttcagag
     4801 cgcttgggga cagaacttcc tttctttatt aaaagtggag tcactattcc taaaaaaatc
     4861 ctacttatag atgatatcta tactacagga gcaactataa atcgtgttaa gaaactgttg
     4921 gaagaagctg gtgctaagga tgtaaaaaca ttttcccttg taagatgagg aaaaaatttg
     4981 caaaaataga atgaaagcgt tataataaaa tcataaaaac aaaaatgttt agaaagaagg
     5041 tactcatatg attaaatata gtatccgtgg tgaaaaccta gaagtaacag aagcaattcg
     5101 tgattatgta gtttctaaac tcgaaaagat cgaaaagtac ttccaaccag aacaagagtt
     5161 ggatgcccga attaacttaa aagtttatcg tgaaaaaacg gctaaagtgg aagtaacgat
     5221 tccgcttgga tctattactc tccgcgcaga agatgtatct caagatatgt atggttcaat
     5281 tgaccttgta actgataaaa ttgaacgtca gattcgtaaa aataaaacaa aaatcgagcg
     5341 taaaaataaa aataaggtag caactggtca attatttaca gatgctttgg tggaagattc
     5401 aaatgttgtc cagtctaaag ttgttcgttc aaaacaaatt gatttaaaac caatggattt
     5461 ggaagaagca attctacaaa tggatttatt ggggcatgat ttctttatct atgtggatgt
     5521 tgaagatcag acaaccaatg tgatttatcg tcgtgaggat ggcgaaattg gtttgttaga
     5581 ggttaaagaa tcttaatttc aatatgtgta aaggtaggtt tactgaattg taaactacct
     5641 ttttcttata attgatagaa ttactgatta cacttttaaa aagtcgcttt ttgaggggta
     5701 ttatggtata atgggtgcca agaggttttg aatgaaaaaa ttttatgtaa gtccaatttt
     5761 tcctattcta gtaggattga ttgcgtttgg agtcttatcc actttcatta tttttgttaa
     5821 taataatctg ttgacggttt taattttgtt tctttttgta ggaggctatg tttttttatt
     5881 taagaaactg agagtgcatt atacaaggag tgatgtagaa cagatacagt atgtaaacca
     5941 ccaagcggaa gaaagtttga catctctatt ggaacaaatg cctgtaggtg ttatgaaatt
     6001 gaatttatct tctggagagg ttgagtggtt taatccctat gctgaattga ttttgaccaa
     6061 ggaagatggt gattttgatt tagaagctgt tcaaacgatt atcaaggctt cagtaggaaa
     6121 tccgtctact tatgccaagc ttggtgagaa gcgttatgct gttcatatgg atgcttcttc
     6181 cggtgttttg tattttgtag atgtatccag ggaacaagcc ataacagatg aattggtaac
     6241 aagtcgacca gtgattggga ttgtctctgt ggataattat gatgatttgg aggatgcaac
     6301 ttctgagtca gatattagtc aaatcaatag ttttgtagct aattttatat cagagttttc
     6361 agaaaaatac atgatgtttt ctcgtcgggt aagtatggat cgattttatc tatttactga
     6421 ctacacggtg cttgagggct tgatgaatga taaattttct gttattgatg ctttcagaga
     6481 agagtcgaaa cagagacagt tgcccttgac cttaagtatg ggattttctt atggcgatgg
     6541 aaatcatgat gagataggga aagttgcttt gctcaatttg aacttggctg aagtacgtgg
     6601 tggcgaccag gtggttgtta aggaaaacga cgaaacgaaa aatccagttt attttggtgg
     6661 tgggtctgct gcttcaatca agcgtacacg gactcgtacg cgcgctatga tgacagctat
     6721 ttcagataag attcggagtg tagatcatgt ttttgtagtc ggtcacaaaa atttagacat
     6781 ggatgctttg ggctctgctg taggtatgca gttgttcgcc agcaatgtga ttgaaaatag
     6841 ctatgctctt tatgatgaag aacaaatgtc tccagatatt gaacgagctg tttcattcat
     6901 agaaaaagaa ggagttacga agttgttgtc tgttaaggat gcaatgggga tggtgaccaa
     6961 tcgttctttg ttgattcttg tagaccattc aaagacagcc ttaacattat caaaagaatt
     7021 ttatgattta tttacccaaa ccattgttat tgaccaccat agaagggatc aggattttcc
     7081 agataatgcg gttattactt atatcgaaag tggtgcaagt agtgccagtg agttggtaac
     7141 ggaattgatt cagttccaga attctaagaa aaatcgtttg agtcgtatgc aagcaagtgt
     7201 cttgatggct ggtatgatgt tggatactaa aaatttcacc tcgcgagtaa ctagtcggac
     7261 atttgatgtt gctagctatc tcagaacgcg cggaagtgat agtattgcta tccaggaaat
     7321 cgctgcgaca gattttgaag aatatcgtga ggtcaatgaa cttattttac aggggcgtaa
     7381 attaggttca gatgtactaa tagcagaggc taaggacacg aaatgctatg atacagttgt
     7441 tattagtaag gcagcagatg ccatgttagc catgtcaggt attgaagcga gttttgttct
     7501 tgcgaagaat acacaaggat ttatctctat ctcagctcga agtcgtagta aactgaatgt
     7561 acaacggatt atggaagagt taggcggtgg aggccacttt aatttggcag cagctcaaat
     7621 taaagatgta accttgtcag aagcaggtga aaaactgaca gaaattgtat taaatgaaat
     7681 aaaggaaaag gagaaagaag aatgaaagta atctttttag cagatgttaa aggaaaaggt
     7741 aaaaaaggcg aaattaagga agtaccaaca gggtatgcgc aaaactttct tatcaaaaag
     7801 aatctagcca aagaagcgac tgctcaagct gtaggtgaac ttcgtggtaa acaaaaatcg
     7861 gaagaaaaag ctcacgctga gatgattgca gaagggaaag caattaaagc acaacttgaa
     7921 gcagaagaaa ctgttgtaga atttgttgaa aaagttggtc cagatggtcg tacctttggt
     7981 tctattacca ataagaagat tgcagaagaa ttacaaaagc aatttggaat taagattgat
     8041 aaacgtcata ttcaagtaca agctccgatt cgagcggttg gtttgattga tgtgccagtg
     8101 aaaatctatc aagatatcac aagtgtaatc aatcttcgtg tgaaagaagg ataagtttac
     8161 accttcttga caagattgta aaaggaaggg aagtctgatg gcagaagtag aagagttacg
     8221 agtacaacct caagatatct tagctgagca atccgtttta ggggctatct ttattgatga
     8281 gagtaaactt gtttttgtgc gagaatacat tgagtctcgg gactttttta agtatgccca
     8341 tcgtttgatt ttccaagcca tggtcgattt atccgatcgt ggtgatgcca tagatgcaac
     8401 aacggttcgt actatccttg ataatcaagg tgatttacag aatattggtg gcttgtctta
     8461 cttggttgag attgtcaatt ctgtgccaac ttctgctaat gcggagtatt atgctaagat
     8521 tgttgcagaa aaagcaatgc tacgtcgttt aattgccaag ttgacagagt ctgtcaacca
     8581 agcttacgaa gcgtcacaac cagctgatga aattattgct caggcagaaa aagggctgat
     8641 tgatgtcagt gaaaatgcaa atcgaagcgg gtttaagaac attcgagatg tgttgaatct
     8701 caactttgga aatctggaag ctcgctcgca acaaacgacc gatattacag gtattgcgac
     8761 aggttatcgt gatttggatc atatgacaac aggacttcat gaggaggagt tgattatctt
     8821 agcagctcgt ccagcagttg gtaagacagc atttgccttg aatatcgctc agaatattgg
     8881 gactaagttg gacaaaacgg ttgctatttt ttcactcgaa atgggtgcgg aaagcttggt
     8941 agaccgtatg ttagctgcag aaggcttggt ggagtcacat tctatccgta cagggcaatt
     9001 gacagatgag gagtggcaaa aatatactat tgctcagggt aatctagcta acgccagtat
     9061 ctatatcgat gatacgccag gtattcggat tacagagatt cgttctcgtt ctcgtaaatt
     9121 ggctcaagaa actggaaatc ttggtttgat tttgatagac tatttgcaac ttatcacggg
     9181 aactggtcga gaaaatcgtc aacaagaagt ttctgaaatt tctcgtcagt tgaaaatact
     9241 agccaaggaa ttgaaggttc cagtaatcgc tctgagtcag ctttctcgtg gtgtagaaca
     9301 acgtcaggac aagagaccgg tcttgtctga tattcgtgaa tctgggtcta ttgagcagga
     9361 cgctgatatc gtagcttttc tctatcgcga tgactactat gaacgtggtg gtgaagaaga
     9421 ggagggtatc ccaaataata aggtggaagt tattatcgag aaaaaccgta gtggagctcg
     9481 tggaacagtg gaattgattt tccaaaaaga atacaataaa ttttcaagta tctcaaagag
     9541 ggaggcataa gatgtcagat gcatttacag atgtagccaa gatgaaaaaa atcaaagaag
     9601 aaatcaaggc acatgaggga caagtcgtag aaatgacttt ggagaatggt cgtaagcgcc
     9661 aaaaaaatag attgggtaag ctaattgaag tttatccatc cctatttatt gtggagtttg
     9721 gggatgtgga aggagataaa caagttaatg tttacgttga atcctttact tactcagata
     9781 ttcttacaga aaagaatttg attcattatc ttgactaaag tgagaaattt tctcactttt
     9841 tcttttttct ccgaataatt taggtgaagg caatcatcgc tttatattat tttttaagga
     9901 ggaagaatga aaattttacc gtttatagca agaggaacaa gttattactt gaagatgtca
     9961 gttaaaaagc ttgttccttt tttagtagta ggattgatgc tagcagctgg tgatagtgtc
    10021 tatgcctatt ccggaggaaa tggatcgatt gcgcgtgggg atgattatcc tgcttattat
    10081 aaaaatggga gtcaggagat tgatcagtgg cgcatgtatt ctcgtcagtg tacttctttt
    10141 gtagcctttc gtttgagtaa tgtcaatggt tttgaaattc cggcagctta tggaaatgcg
    10201 aatgaatggg gacatcgtgc tcgtcgggaa ggttatcgtg tagataatac accgacgatt
    10261 ggttccatta cttggtctac tgcaggaact tatggtcatg ttgcctgggt gtcaaatgta
    10321 atgggagatc agattgagat tgaggaatat aactatggtt atacagaatc ctataataaa
    10381 cgaattataa aagcaaacac gatgacagga tttattcatt ttaaagattt ggatggtggc
    10441 agtgttggga atagtcaatc ctcaacttca acaggcggaa ctcattattt taagaccaag
    10501 tctgctatta aaactgaacc cctagttagt gcaactgtga ttgattacta ttatcctgga
    10561 gagaaggttc attatgatca aattctcgaa aaagacggct acaagtggtt gagttatact
    10621 gcctataatg gaagctatcg ttatgttcaa ttggaggctg tgaataaaaa tcctctaggt
    10681 aattctgttc tttcttcaac aggtggaact cattatttta agaccaagtc tgctatcaaa
    10741 actgaacccc tagttagtgc aactgtgatt gattactatt atcctgggga gaaggttcat
    10801 tatgatcaga tacttgaaaa agacggctac aagtggttga gttatacggc ttataacgga
    10861 agtcgtcgct atatacagct agagggagtg acttcttcac aaaattatca gaatcaatca
    10921 ggaaatatct ctagctatgg atccaataat agttcaactg tcggttggaa gaaaataaat
    10981 ggtagttggt atcatttcaa atcaaatggt tctaaatcaa caggatggct gaaagatggt
    11041 tctagctggt attatttgaa attatctggt gaaatgcaga caggatggtt aaaggagaat
    11101 ggctcgtggt attatctggg tagttcaggg gcaatgaaaa caggctggta ccaggtctct
    11161 ggtaagtggt attattctta ctcttcaggc gccttagctg ttaatacgac ggtggatggc
    11221 tacagagtaa acagtgatgg agaacgagta tagaaaattg gagtaggaga aatttcctgc
    11281 tcttttctgt aagcagtttc cttgacattt ttcttatttt gcgctatcat atatacatat
    11341 aatatatggg agtctgtgta cagtctgaga ggaagtgtta aacttcgacc gcacctgatc
    11401 tgggtaatgc cagcggaggg aacgatactt agtctaattt tgcacctttt ccatgtatgg
    11461 taaaggtttt tctttttttt aaaaggaaaa cgagaagagg aggttcttat gaaagcaagc
    11521 attgccttgc aagttttacc cctagtacag gggattgatc ggatagctgt tattgatcag
    11581 gtcattgctt atctgcaaac tcaagaagtg ccgatggtag tgacaccatt tgaaacggtc
    11641 ttggaagggg agtttgatga gcttatgcgc attctaaaag aagcgctgga agtggcaggg
    11701 caggaggcag acaatgtctt tgccaatgtc aaaataaatg taggagagat tttaagtatt
    11761 gatgagaaac ttgagaagta tactgagacg acacattagt ctattgggct ttctcggagt
    11821 cttgtcaatc tggcagttag caggttttct taaactgctc cccaagttta tcctgccgac
    11881 acctcttgaa attctccagc cctttgttcg tgacagagaa tttctctggc accatagctg
    11941 ggcgaccttg agagtggctt tactggggct gattttggga gttttgattg cctgtcttat
    12001 ggctgtactc atggatagtt tgacttggct caatgacctg atttacccta tgatggtggt
    12061 cattcagacc attccgacca ttgccatagc tcctatcctg gtcttgtggc taggttatgg
    12121 gattttgccc aagattgtct tgattatctt aacgacaacc tttcccatca tcgtcagcat
    12181 tttggacggt tttaggcatt gcgacaagga tatgctgact ttgtttagtc tgatgcgggc
    12241 caagccttgg caaatcctgt ggcattttaa aattccagtc agcctgccct acttttatgc
    12301 tggtctgagg gtcagtgtct cctacgcttt tatcacaaca gtggtatctg agtggttggg
    12361 aggctttgag gggcttggtg tttatatgat tcagtccaag aaattgtttc agtatgatac
    12421 catgttcgct attattattc tggtatcgat tatcagcctt ttgggtatga agttggtcga
    12481 tattagtgaa aaatatgtta ttaaatggaa acgttcgtag aattagaatg tttctgaaaa
    12541 agaaaagagg aaatcaaaat gaagaaaaca tggaaagtgt ttttaacgct tgtaacagct
    12601 cttgtagctg ttgtgcttgt ggcctgtggt caaggaactg cttctaaaga caacaaagag
    12661 gcagaactta agaaggttga ctttatccta gactggacac caaataccaa ccacacaggg
    12721 ctttatgttg ccaaggaaaa aggttatttc aaagaagctg gagtggatgt tgatttgaaa
    12781 ttgccaccag aagaaagttc ttctgacttg gttatcaacg gaaaggcacc atttgcagtg
    12841 tatttccaag actacatggc taagaaattg gaaaaaggag caggaatcac tgccgttgca
    12901 gctattgttg aacacaatac atcaggaatc atctctcgta aatctgataa tgtaagcagt
    12961 ccaaaagact tggttggtaa gaaatatggg acatggaatg acccaactga acttgctatg
    13021 ttgaaaacct tggtagaatc tcaaggtgga gactttgaga aggttgaaaa agtaccaaat
    13081 aacgactcaa actcaatcac accgattgcc aatggcgtct ttgatactgc ttggatttac
    13141 tacggttggg atggtatcct tgctaaatct caaggtgtag atgctaactt catgtacttg
    13201 aaagactatg tcaaggagtt tgactactat tcaccagtta tcatcgcaaa taacgactat
    13261 ctgaaagata acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa aggctaccaa
    13321 tatgccatgg aacatccaga agaagctgca gatattctca tcaagaatgc acctgaactc
    13381 aaggaaaaac gtgactttgt catcgaatct caaaaatact tgtcaaaaga atacgcaagc
    13441 gacaaggaaa aatggggtca atttgacgca gctcgctgga atgctttcta caaatgggat
    13501 aaagaaaatg gtatccttaa agaagacttg acagacaaag gcttcaccaa cgaatttgtg
    13561 aaataatgac agaaattaga ctagagcacg tcagttatgc ctatggtcag gagaggattt
    13621 tagaggatat caacctacag gtgacttcag gcgaagtggt ttccatccta ggcccaagtg
    13681 gtgttggaaa gaccaccctc tttaatctaa tcgctgggat tttagaagtt cagtcaggga
    13741 gaattgtcct tgatggtgaa gaaaatccca aggggcgcgt gagttatatg ttgcaaaagg
    13801 atctgctctt ggagcacaag acggtgcttg gaaatatcat tctgcccctc ttgattcaaa
    13861 aggtggataa ggcagaagct atttcccgag cggataaaat tcttgcgacc ttccagctga
    13921 cagctgtaag agacaagtat cctcatgaac ttagcggtgg gatgcgccag cgtgtagcct
    13981 tactccggac ctaccttttt gggcacaagc tctttctctt agatgaggcc tttagcgcct
    14041 tggatgagat gacaaagatg gaactccacg cttggtacct tgagattcac aagcagttgc
    14101 agctaacaac cttgattatt actcacagta tcgaggaggc cctcaatctc agtgaccgta
    14161 tctatatctt gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta gattggtctg
    14221 aagatgagga caaggaagtc caaaagattg cctacaaacg tcaaatcttg gcagaattag
    14281 gcttagataa gtagaaaaat agggagttgg tgaagattat cctttaccag cgcccttttt
    14341 cttttaaaaa tgagaaaatt tcggtataat agtcaaacaa ggtcaaggtc taaagagaga
    14401 ggtgggtttg ttatgagatt taaaaataca tcggatcata ttgaggccta catcaaggcg
    14461 attttagatc aatctggtat cgtggagttg caacggagtc agttggcaga tacctttcag
    14521 gttgttccta gtcagattaa ctacgtgatc aagacacgct ttacggaaag tagaggctac
    14581 ttggttgaaa gtaagcgtgg tggcggaggc tacattcgta taggacggat tgagttttct
    14641 agtcatcatg aaatgctccg ggagctgctt tactcgattg gtgagcgagt cagtcaagaa
    14701 atttatgagg atattctcca gcttttggtt gagcaggaat tgatgaccaa gcaggagatg
    14761 aatttgctag aatcagtagc tttggatcgc gttttaggag aagaagctcc agttgttcga
    14821 gcaaacatgc tacgtcagat tatacaagag gtagatagaa aagggaagta agatgaacta
    14881 ttcaaaagca ttgaatgaat gtatcgaaag tgcctacatg gttgctggac attttggagc
    14941 tcgttatcta gagtcttggc acttgttgat tgccatgtct aatcatagtt atagtgtagc
    15001 aggggcaact ttaaatgatt atccgtatga gatggaccgt ttagaagagg tggctttgga
    15061 actgactgaa acggactata gccaggatga aacctttacg gaattgccgt tctcccgtcg
    15121 tttgcaggtt ctttttgacg aagcagagta tgtagcgtca gtggtccatg ctaaggtgct
    15181 agggacagag cacgtcctct atgcgatttt gcatgatggc aatgccttgg caactcgtat
    15241 cttggagagg gctggttttt cttatgaaga caagaaagat caggtcaaga ttgctaccct
    15301 tcgtcgaaat ttagaagaac gggcaggatg gactcgtgaa gatctcaagg ctttacgcca
    15361 acgccatcgt acagtagctg acaggcaaaa ttctatggcc aatatgatgg gcatgccgca
    15421 gactcctagt ggtggtctcg aggattatac gcatgatttg acagagcaag cgcgttctgg
    15481 caagttagaa ccagtcatcg gtcgggacaa ggaaatctca cgtatgattc aaatcttgag
    15541 ccggaagact aagaacaacc ctgtcttggt tggggatgct ggtgtcggga aaacagctct
    15601 ggcgcttggt cttgcccagc gtattgctag tggtgacgtg cctgcggaaa tggctaagat
    15661 gcgcgtgtta gaacttgatt tgatgaatgt cgttgcaggg acacgcttcc gtggtgactt
    15721 tgaagaacgc atgaataata tcatcaagga tattgaagaa gatggccaag tcatcctctt
    15781 tatcgatgaa ctccacacca tcatgggttc tggtagcgga attgattcga ctctggatgc
    15841 ggccaatatc ttgaaaccag ccttggcgcg tggaactttg agaacggttg gtgccaccac
    15901 tcaggaagaa tatcaaaaac atatcgaaaa agatgcggca ctttctcgtc gtttcgctaa
    15961 agtgacgatt gaagaaccaa gtgtggcaga tagtatgact attttacaag gtttgaaggc
    16021 gacttatgag aaacatcacc gtgtacaaat cacagatgaa gcggttgaaa cagcggttaa
    16081 gatggctcat cgttatttaa ccagtcgtca cttgccagac tctgctatcg acctcttgga
    16141 cgaagcagca gcaacagtgc aaaataaggc aaagcatgta aaagcagacg attcagattt
    16201 gagtccagct gacaaggccc tgatggatgg caagtggaaa caggcagccc agctaatcgc
    16261 aaaagaagag gaagtacctg tctacaaaga cttggtgaca gagtctgata ttttgaccac
    16321 cttgagtcgc ttgtcaggaa tcccagttca aaagctgact cagactgacg ctaagaaata
    16381 tctaaatctt gaagcagaac tccataaacg ggttatcggt caagatcaag ctgtttcaag
    16441 tattagtcgt gccattcgcc gtaatcagtc aggaattcgc agtcacaagc gtccgatcgg
    16501 ttcctttatg ttcctaggac ccacaggtgt cggtaagacc gagttggcca aggctttggc
    16561 agaagttctc tttgatgacg aatcagccct tatccgcttt gatatgagtg agtatatgga
    16621 gaaattcgca gccagccgtc taaatggagc tcctccaggc tatgtgggtt acgaagaagg
    16681 tggggagttg acagagaagg ttcgcaataa accctattcc gttctcctct ttgatgaggt
    16741 agagaaggcc cacccagata tctttaatgt tctcttgcag gttctggatg acggtgtctt
    16801 gacagatagc aagggacgca aggtcgattt ttcaaatacc attatcatta tgacatcgaa
    16861 tctaggtgcg actgcccttc gtgatgataa gactgttggt tttggggcta aggatattcg
    16921 ttttgaccag gaaaatatgg aaaaacgcat gtttgaagaa ctgaaaaaag cttatagacc
    16981 ggaattcatc aaccgcattg atgagaaggt ggtcttccat agcctatcta gtgaccatat
    17041 gcaggaagtg gtgaagatta tggtcaagcc tttagtggca agtttggctg aaaaaggcat
    17101 tgacttgaaa ttacaagctt cagctctgaa attgttagca aatcaaggat atgacccaga
    17161 gatgggagct cgcccacttc gcagaacctt gcaaacagaa gtggaagaca agttggcaga
    17221 acttcttctt aagggagatt tagtggcagg caacacactt aagattggtg tcaaagcagg
    17281 ccagttaaaa tttgatattg cataaaagaa taaaagtatc agcatctgac cataagtcac
    17341 agtggagtga aactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc
    17401 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
    17461 ataagctgca agatgaatga ttttcttgta ttgacgttgt tgttgacaaa aagtagcgga
    17521 taaatgaaat ccattccatt atcatagatg ataggctggt aggaaatttt caaatagcat
    17581 acaggaaata gatgtatgga gttctggtag tagaaaggga gagagatgaa cattttagtt
    17641 gcagatgacg aggaaatgat tagagaagga attgcagcat ttctgacaga agagggttat
    17701 catgtcatta tggctaagga tggacaagag gtcttggaaa aatttcaaga tctccctatc
    17761 catctcatgg tattggattt aatgatgcct aggaagagtg gttttgaagt gttaaaagaa
    17821 atcaatcaaa agcacgatat tcctgtcatc gtcttgagtg ctctgggaga tgaaactact
    17881 cagtcacagg tatttgatct ctatgctgat gatcatgtga caaaaccttt ttctttggta
    17941 ctgcttgtca agcgtattaa ggcgcttatc agacgttact acgtcataga ggatatttgg
    18001 cgatatcagg atgtaacagt ggattttacc tcttacaaag cacattataa aaatgaagaa
    18061 attgatctca aaccaaagga attactggta ctaaagtgtt tgattcagca taaaaatcaa
    18121 gttttaagta gagagcagat attggaagaa atttcaaaag atgtagctga tttaccttgt
    18181 gatagggtcg ttgatgtcta tattcgtact cttcgcaaaa aattagcttt agattgtatc
    18241 gtgactgtga aaaatgttgg gtataagatt agtttatgat aaaaaatcct aaattattaa
    18301 ccaagtcctt tttaagaagt tttgcaattc taggtggtgt tggtctagtc attcatatag
    18361 ctatttattt gacctttcct ttttattata ttcaactgga gggggaaaag tttaatgaga
    18421 gcgcaagagt gtttacggag tatttaaaga ctaagacatc tgatgaaatt ccaagcttac
    18481 tccagtctta ttcaaagtcc ttgaccatat ctgctcacct taaaagagat attgtagata
    18541 agcggctccc tcttgtgcat gacttggata ttaaagatgg aaagctatca aattatatcg
    18601 tgatgttaga tatgtctgtt agtacagcag atggtaaaca ggtaacagtg caatttgttc
    18661 acggggtgga tgtctacaaa gaagcaaaga atattttgct tttgtatctc ccatatacat
    18721 ttttggttac aattgctttt tcctttgttt tttcttattt ttatactaaa cgcttgctca
    18781 atcctctttt ttacatttca gaagtgacta gtaaaatgca agatttggat gacaatattc
    18841 gttttgatga aagtaggaaa gatgaagttg gtgaagttgg aaaacagatt aatggtatgt
    18901 atgagcactt gttgaaggtt atttatgagt tggaaagtcg taatgagcaa attgtaaaat
    18961 tgcaaaatca aaaggtttcc tttgtccgcg gagcatcaca tgagttgaaa acccctttag
    19021 ccagtcttag aattatccta gagaatatgc agcataatat tggagattac aaagatcatc
    19081 caaaatatat tgcaaagagt ataaataaga ttgaccagat gagccactta ttagaagaag
    19141 tactggagtc ttctaaattc caagagtgga cagagtgtcg tgagaccttg actgttaagc
    19201 cagttttagt agatatttta tcacgttatc aagaattagc tcattcaata ggtgttacaa
    19261 ttgaaaatca attgacagat gctaccaggg tcgtcatgag tcttagggca ttggataagg
    19321 ttttgacaaa cctgattagt aatgcaatta aatattcaga taaaaatggg cgtgtaatca
    19381 tatccgagca agatggctat ctctctatca aaaatacatg tgcgcctcta agtgaccaag
    19441 aactagaaca tttatttgat atattctatc attctcaaat cgtgacagat aaggatgaaa
    19501 gttccggttt gggtctttac attgtgagta atattttaga aagctatcaa atggactata
    19561 gttttctccc ttatgaacac ggtatggaat ttaagattag cttgtagaca gattagtttt
    19621 ttattaaagt tcacataggg ttaacataag tgtattattc tttatataga taaaaatata
    19681 gataaaagaa aggatactaa tatggtatta gcgattattt tagtaacatt ccttattcga
    19741 ttgatttttt taaagcgttc gatagagaat gagaaacgaa tccttagcaa tggcgggaaa
    19801 gaatttggag ttgagaatac aaaacgatta actatggctc atattgtttt ttatctctct
    19861 tgcttggttg aggcaatggt gcacaagaca atttttgata gcatgggcat ggttggttta
    19921 gtcttgctta ttttttctat gctgatgtta atgttggtga ttcacttgtt gggagatatt
    19981 tggacagtga agcttatgct tgtcaataat cacaaatatg tagatcatat cttgtttagg
    20041 acagtaaaac atcctaatta ctttttaaat attcttcctg agttgattgg cttgaccttg
    20101 ttgagtcatg cttatgtgac ttttgtttta gtttttccag tttatgcagt tattttgtat
    20161 cgacgaatag ctgaagagga aaagctatta catgaagtta taatcccaaa tggaagaatg
    20221 aaaggttaaa aataaaatac ccaatttaat atacagttca tattggaagg gtatactgaa
    20281 gatgaataaa atattatagg atatcgatat gtttaaatca aattatgaaa gaaaaatgtg
    20341 ctattctatt cgaaaattta gtataggagt agctagtgta gctgttgcca gtcttgttat
    20401 gggaagtgtg gttcatgcga cagagaacga gggaactacc caagcaccca cttcttctaa
    20461 taggggaaat gaaagtcagg cagaacaacg tagagaactc gatttagaac gagataaggt
    20521 aaagaaagag gtcagggaat ataaagaaaa aaaagtgaaa gagctctatt caaaatcaac
    20581 taaaagtcga cataagaaga ctgtagatat agttaacaag ttgcaaaaca ttaataacga
    20641 gtatttgaat aaaataattc aatcaacctc aacatacgaa gaactacaga aactgatgat
    20701 ggagagtcaa tcagaagtag ataaagctgt gtctgaattt gaaaaggact tatcttcttc
    20761 gtcaagttca ggctcttcca cggaaccgga agcttcagat acagcgaagc caaacaagcc
    20821 gacagaacta gaaaaaaagg tagcagaagc tcagcagaag gttgaagaag ctgagaaaaa
    20881 agccaaggat caaaaagaag aagattaccg taactaccca accattactt acaaaacgct
    20941 tgaacttgaa attgctgagt tcgatgtgaa agttaaagaa gcggagcttg aactattaaa
    21001 agtgaaagct aaggaatctc gagacgagaa aaaaattaag caagcagaag cggaagttga
    21061 gagtaaacaa gctgaggcta caaggttaaa aaaaatcaag acagatcgta aaaaagcaga
    21121 agaagaagct aagttgaagg aagctgttga aaagaatgca gcgacttcag agcaaggtaa
    21181 accaaagagg cgggtaaaac gaggagctct tggagagcaa gcaacacctg ataaaaaaga
    21241 ttattttgaa aaagacttcc gtccagcttt caataaaaac cagcagatgg tagccattca
    21301 agaatccttg aacaaactag atgatgaaac aaaaactgtt ccagatgggg ctaaactcac
    21361 aggagaagct ggaaatgcct ataatgaggt cagagattat gcaataaaag ttgtttctga
    21421 aaacaagaaa cttctatcac agacagcagt gacaatggat gaactggcaa tgcaattaac
    21481 caaattgaac gatgccatgt ctaaattgaa agaagctaaa gcgaaattgg taccagaggt
    21541 taaaccgcag ccggaaaatc cagagcatca aaaaccaaca actccagctc cggataccaa
    21601 accaatccct caaccagagg gtaagaaacc aagcgtacca gatattaatc aggaaaaaga
    21661 aaaagctaag cttgctgtag caacctacat gagcaagatt ttagatgata tacaaaaaca
    21721 tcatctgcag aaagaaaaac atcgtcagat tgttgctctt attaaggagc ttgatgagtt
    21781 taaaaagcaa gctctttctg aaattgataa tgtaaatacc aaagtagaaa ttgaaaatac
    21841 agtccacaag atatttgcag acatggatgc agttgtgact aaattcaaaa aaggcttaac
    21901 tcaggacaca ccaaaagaac cagataa
//
LOCUS       DBEJJE010000036        21843 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEJJE010000036 DBEJJE010000000
VERSION     DBEJJE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.36"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..70
                     /gene="tnpB"
                     /locus_tag="ACL3F5_001431"
     CDS             <1..70
                     /gene="tnpB"
                     /locus_tag="ACL3F5_001431"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0515213.1"
                     /translation="ALYWDGQGFWLLYKRFENGKLT"
     gene            complement(886..2613)
                     /gene="ezrA"
                     /locus_tag="ACL3F5_001432"
     CDS             complement(886..2613)
                     /gene="ezrA"
                     /locus_tag="ACL3F5_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0515214.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2695..4641)
                     /gene="gyrB"
                     /locus_tag="ACL3F5_001433"
     CDS             complement(2695..4641)
                     /gene="gyrB"
                     /locus_tag="ACL3F5_001433"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0515215.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4656..5219)
                     /locus_tag="ACL3F5_001434"
     CDS             complement(4656..5219)
                     /locus_tag="ACL3F5_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0515216.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5304..5858)
                     /locus_tag="ACL3F5_001435"
     CDS             complement(5304..5858)
                     /locus_tag="ACL3F5_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0515217.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5869..7092)
                     /locus_tag="ACL3F5_001436"
     CDS             complement(5869..7092)
                     /locus_tag="ACL3F5_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0515218.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7129..9579)
                     /locus_tag="ACL3F5_001437"
     CDS             complement(7129..9579)
                     /locus_tag="ACL3F5_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0515219.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVGHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9779..10708)
                     /locus_tag="ACL3F5_001438"
     CDS             complement(9779..10708)
                     /locus_tag="ACL3F5_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0515220.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10848..11135
                     /locus_tag="ACL3F5_001439"
     CDS             10848..11135
                     /locus_tag="ACL3F5_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0515221.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11169..12503)
                     /gene="ciaH"
                     /locus_tag="ACL3F5_001440"
     CDS             complement(11169..12503)
                     /gene="ciaH"
                     /locus_tag="ACL3F5_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0515222.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12493..13167)
                     /gene="ciaR"
                     /locus_tag="ACL3F5_001441"
     CDS             complement(12493..13167)
                     /gene="ciaR"
                     /locus_tag="ACL3F5_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0515223.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13276..15822)
                     /locus_tag="ACL3F5_001442"
     CDS             complement(13276..15822)
                     /locus_tag="ACL3F5_001442"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0515224.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15945..16349)
                     /locus_tag="ACL3F5_001443"
     CDS             complement(15945..16349)
                     /locus_tag="ACL3F5_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0515225.1"
                     /translation="MNPLIGDEIDAWAFGVEPDLLADLVFKGEKTATASAYDLYVLED
                     EPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGEGDKSLAYWRQVH
                     EDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16360..17229)
                     /locus_tag="ACL3F5_001444"
     CDS             complement(16360..17229)
                     /locus_tag="ACL3F5_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0515226.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17271..17999)
                     /locus_tag="ACL3F5_001445"
     CDS             complement(17271..17999)
                     /locus_tag="ACL3F5_001445"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515227.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(18007..18486)
                     /locus_tag="ACL3F5_001446"
     CDS             complement(18007..18486)
                     /locus_tag="ACL3F5_001446"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0515228.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18497..19195)
                     /locus_tag="ACL3F5_001447"
     CDS             complement(18497..19195)
                     /locus_tag="ACL3F5_001447"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0515229.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19188..19424)
                     /locus_tag="ACL3F5_001448"
     CDS             complement(19188..19424)
                     /locus_tag="ACL3F5_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0515230.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19522..20448)
                     /locus_tag="ACL3F5_001449"
     CDS             complement(19522..20448)
                     /locus_tag="ACL3F5_001449"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0515231.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELAETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20523..21338)
                     /locus_tag="ACL3F5_001450"
     CDS             complement(20523..21338)
                     /locus_tag="ACL3F5_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515232.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21342..21662)
                     /locus_tag="ACL3F5_001451"
     CDS             complement(21342..21662)
                     /locus_tag="ACL3F5_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0515233.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6601 a         4762 c         3835 g         6645 t
ORIGIN      
        1 agccctttac tgggatggtc aaggattttg gctactatat aaacgctttg agaacggaaa
       61 actgacttga ccaagtacag aaaaggatgt caaagctctc acaccagaac aagtagactg
      121 gcttatgaag ggcttttcta tcactcccca aatatagtgg atttaaacta gaatagtaca
      181 cccctacttc taaaacattg ttagaaatcg atttgactgt cctaatcgat ttgtcctgtt
      241 cttgtttcat tttactatag aacgatttga aggcgtttat gatatttagc tgtacgagag
      301 tcttttaaaa gtgttttgat ggtttggatt tcttctttag ttgatttcat attactatta
      361 tatagtgctt ttttatttta gtctggtata aatagcgaga aatatctatc ctatcttcta
      421 gaatgtcttc caaacgagaa aactctcgta aacaaagagg ttttagaggc ctatttaccg
      481 tagactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg aactatccgt
      541 gagttctcta gtctggagat ttttcaatag acttcattat tggacggtta ccaagttact
      601 caaagtacag atttgaagct gcagataaga ctgacgaaat cactttaata ctaaatgaaa
      661 atcaaaaagc aaactaagaa gctagcctca ggctgtactt gagtacggta aggcgacgct
      721 gacgtgattt gaagagattt tcgaagagta taaaacactg ttttgaggtg gtggataaat
      781 cggctgggca aaaactcaat ctcaggagaa aatgaagtaa atctccccac aactatagaa
      841 aaagatttga ttctgctcct cacacaataa aatctttttc ttttattaaa aacgaatcgt
      901 ttcacgtgtt ttctcatatg aggtaacaaa gcgattggtt acaccaggct ctgccacttc
      961 caatgcttga gaaatcttgt caaatgaagc gtgataatca aattcttttt caaaaatatc
     1021 taaagcttcg ttaaatgctt cttgaatgcg ttcatcaaat gagcgatagc ggttagaata
     1081 ttgcaagagt tgctctgtca aagttgcata ttgtacaata ttataagttt ccgtttctaa
     1141 agcttccata tcattcgttg caatttcaag aactcgggta acagattcaa tgttaatcat
     1201 tttttgttct aactcaacca ttaaatcctc ggtattattg cttgccgtaa agaataactt
     1261 caagaaagtt tgtggaatac ctggcagatt gcgtttttcc atgtatcgct tgatagtatg
     1321 gagacgattg acataaacat tggccttttg acgtgcatta atatcatctt tctcaatttg
     1381 tgtcaggcgc tcactaactg aaatttgctc atcttcaata tcttttagtt gagtttgtaa
     1441 atcctcaaga ttttcttcaa gaactgaata agcttgggtt ggttcttctt gatttgaagt
     1501 tacctcaaca atagctgcct caaaactctc taattctgtc tgaatacgac gaacatggct
     1561 tgcagctgtc tcaggaagta aataggtctt gttcaaacgt gcaatatctt ctcccaataa
     1621 agtattattc tctttcatat gttgaaggta agttggaaga gttgcaagta gattttccac
     1681 tactttctga gcagcaattt ctcgagtaaa aatatcatac aaggcattga tttcctcttg
     1741 tgcctgtcca ttctcatatt cggcattatc caattccaac tgacgaatat tctcttggtt
     1801 tttcttgaat gcttcataaa gcaagtggaa acgcgcttca atatccgttt caacaaaatg
     1861 ataattagca tcaattagtt tacgataacc ggcttccaaa tcctgtaatt gatctggcaa
     1921 ttctgtagaa agcgtcgtaa ccaaggctgg aacacgatcc acaatatgac ttaaggccaa
     1981 aatgtgattt tctgtattat ccaaaatcac tgcggcttcc acagggtcac ccgatgaatt
     2041 caaggttaca aattgtgaaa attcagattg gatattttct aattgttttt caatttcatc
     2101 caaggcttga ccatactgtt ctgaattttc agcaactcta tgctgaagtt cctcaaataa
     2161 atccaaagca tgaagaacac gaccactatt tttagattct tgcttctcta agtctgccaa
     2221 agcattgcga attgccgcaa tatcttcttc aatcaaagta atttgactct caatttggtc
     2281 aatttgatga ctggccttga gaaaacgaaa tgaatggtta tagccttctg cttcaaagag
     2341 attattttca atatcggcaa aagagttgag agataaatcg acccattttt gattccattc
     2401 acggaaagcc acttgacttt gtccaatcaa gtgcatattt tttacagctt ctacttcatc
     2461 atttactgga agattgtata gttcttcttt tctttcttct agcgcctcta atctcccctc
     2521 gtttcgctta cgtagaaaga ttgccactac ataagccaga actaaaatga ctgcaattgc
     2581 aaccattaaa taaattagtt gtccattaga catatcaaac tcctttttta cttgaaacaa
     2641 tcgtaacgat tatatcatat tttttagacc aagggaacta cttctcccta ttttttagac
     2701 atcaagtgta ctatagacag cattttcttc gataaactca cgacgaggct ctactcgatc
     2761 ccccatcaac atatcaaaga ttttatctgc ttctgcagca tcatctacag aaactctagc
     2821 catcaagcga tgttcgggat ccatggttgt ttcccacagc tgatgatcgt ccatttcacc
     2881 tagcccctta taacgctgaa tagtcggttt ggtacgacct tcactataac gggctaaagc
     2941 ttcttggagt ttgatttctt gatctgcacc cggctggata tattctttaa tctcgcttcc
     3001 aaccttgaca ccatagattg gtggttgggc aatataaaca tagccagctt ctaggattgg
     3061 tttcatataa cgataaatca aggttaaaag aagggtacga atgtgggctc catcgacatc
     3121 ggcatcggtc atcaaaacga gtttttggta acgggctttc gaaacatcaa attctgcgcc
     3181 aaatcctgtt cccatggctg tgaaaagact acgaatttct tcgttagcta gaatcttatc
     3241 catacttgct ttttcaacgt tcaaaatctt accgcgaatt ggaaggatag cctgaaactc
     3301 acggttacga ccagatttgg ctgatccacc agctgagtct ccttcgacga tgaagagttc
     3361 tgtttcagca gggttattag aagaacagtc tgctagtttc cctggaaggt tggaaatttc
     3421 caaaccagat tttttacgtg tgacttcacg cgcacgcttg gcagccacac gagccttggc
     3481 agccaaaatt cctttttcta cgatacgttt ggcaatctgt ggattttcca tgaggaaatc
     3541 ggagaaggct tcactgaaga ggcgattggt aatcttgacc acttcgctat ttcccaattt
     3601 ggtcttcgtt tgtccttcaa actgtggatt tgggtgttta actgagataa ctgcagttaa
     3661 gccttcgcga acatcttccc ctgttagatt gtcttcattg tctttcagta acttattctt
     3721 acgagcataa tcgttgataa cacgtgtcaa ggctgtacgg aaaccttgtt catgcgttcc
     3781 accttcatgt gtatgaatat tattggcgaa actcatgaca ttttcatggt aacccgttgt
     3841 gtactgcatg gctacctcaa ctgtgatatc atccatctca ccgtctgtat agattggtgt
     3901 atcaaagatt acatccttgt tctcgttgat atattcaacg taactagcaa tcccaccttc
     3961 ataatgataa tgcttggttt gttccaaacc ttggcgctta tcagtgatag aaatttgaag
     4021 accgcgattt agaaaggcca actcttgaat ccgtttattt aatttatcaa aatcaaagat
     4081 tgttgtttca gtgaagattt ttgggtccgg tgtgaagtga acagttgttc ctgttttatc
     4141 cgtatctcca actatttcaa gatctgcgac aacatgacca cgacggtatt cttggtaatg
     4201 aatcttaccg tttttatgga catgaacgtc taattgagtg gaaagggcat taacaactga
     4261 cgaccccacc ccgtgaagac cacctgaaac cttgtatcca ccaccgccga actttcctcc
     4321 agcgtgaagg actgtaaaga cggtctcaac agcaggacgg cctgtttttt cctgaatatc
     4381 gactgggata ccacgcccat catccacaac agtaatcgaa tcatctggct caataaaaac
     4441 ttgaatatgg ctggcaaatc ctgccaaggc ctcgtcaatt gagttatcaa caatttccca
     4501 gactagatgg tgaagacctt cttttgaggt tgatccaatg tacatccctg gacgcatacg
     4561 aacagcctct aagccctcta aaacttgaat ttgactggca tcataatcct gtgcctgcag
     4621 atttttgatt tcttctgtca tcttattcct ttttcttata tgtctaatac ttgtcttaaa
     4681 ttcacgatac tggtaaacaa gtgggtatca agtcctgcag cttgacctgc ttcgatatca
     4741 atcggccgat caccaatgac aagaccagag ctaatctgat acttttctct taaataaagc
     4801 atggattcgg gatttggctt tctcttaaag cctgagctag aagtcaccac ttctgtaaaa
     4861 taagctgcta tagaggtttt ttctaaaatt tccaaaacct gatcatttcg atgagagacc
     4921 aaaaaatgac ggccaccttg atttaaaatg tcttccaata ggtcagaaac tccttcaaat
     4981 aaaatcgggt gttcaagctc tctggcttca ttttccttgt acttttctaa aaaattctct
     5041 aaattgggag cgaatgtctc aatcgcaaaa ggagtagaaa cctttaaagc ttgatagaca
     5101 ctgtcatggt cttgtgtgat accatacagt gccaatgttt caacaaatgc agctgttgaa
     5161 gtttcataat tatccagtaa agttccacct aaatcccaga tgtaatcgtg atatttcata
     5221 cccttcatta tagcattttt ttatgaaaaa agcgatgatt tccctgagtt ttccacataa
     5281 aaaacgagag aataactccc gttttactga tttttaccaa agacatctcg atagagcatt
     5341 cctgttcgta aactctctgc gtcccctcct agttgctcca ccaactcgta ggcaaaggca
     5401 agggctgttg aaggaccccg actggttgtc aactgaccat ctaccactac tgtttccttg
     5461 acgtagtgac catcaagaat ttgctcttga acgccgtcat aacaagtgta tcgcttattt
     5521 ttcaatatct ctgcttgatt gagggcaatt ggtgccgcac aaatggctgc tagtttcttc
     5581 ccttcttgct caaagctttg caattcttga atcaaggtct gattatcacg taaatgtgca
     5641 gaaccaggca tacctccagg aagaacaatc atatcatagt ctgataaatc tccatcaaag
     5701 acatgatctg ctcttacttg gattgcatgc gaacccgtta cttgctcttc aaaaccaacc
     5761 atatcacatg tgatattggc tcgacgcaag acatctacaa ctgtcaaggc ttcaatttct
     5821 tcaaagccct gagctaacat aactgctact tttaccatga ttttctcctt atttaatttg
     5881 ttttaataca acctttttcc gtttgaatgg gacttttccg ctcttttctt cagctagatt
     5941 agtctggtaa ctcatcgata aaagcaaacc aacaccaatc agattactga taatagctga
     6001 tcccccttgc gaaatgaaag gcaagggaat ccccgtcaaa ggaagtagtc cagtcacagc
     6061 accgatattc tcaaagatgt ggaagagcaa catcataatc aaacctgtgg aaatataagt
     6121 gtagaactgg ttatttgatt taagagtaat cttcaacata cggtaaatca acatgagata
     6181 gagggcaata accaggacag agccaataaa gccaaaatct tctgcaataa ccgtaaaaat
     6241 catatctgac tctcgaactg ggataagcag attcgaagca ttaaatccct gaccaaataa
     6301 gccaccactc ccaatggcaa tctgcccttg agcctgctgg taagtcgttg tttgggcaaa
     6361 ctcaaaggga ttgagccaag ccaaaatccg attaatttgg taggtcggca ttccaatctg
     6421 gtgaagaaaa gctcgtccgt ccttgctaat aaagatagct aagaaaccag caactcctgt
     6481 tacagcagtc acaaatactg ggataataat tttccaagaa acccctgata ataaaacgat
     6541 tcctgagaaa atggctacaa aaaccaaagc cgtccccaag tcactttgaa gtgctaaaag
     6601 aactaggact ggaatggtaa agagaatcat ccagaaaatt aacaaaaagt ccagcggaac
     6661 cgtgcgtctc cattccttat gtttctttgt aaattggaca atgacacgag ccaacatgag
     6721 gatataggat atcttcataa attctgacgg ttgaaatagg gtaattccat ttattgatac
     6781 ccagtttttg gcacccgttg atgcaactaa gcttggatta taaaatacaa tcggcaagat
     6841 cataagtccc aagcctaaaa tatatagaaa gggggtcacc ttccaaagaa attctgtatt
     6901 aaagagcatg accacaaaac caatcacaag ccccaaggca atccaggcga cctgctgccc
     6961 taaaatgggc agaatattat tgggataatc atgactaacg gctatataga tagccaccac
     7021 accgatgacc agtagaaaaa atactggcaa gagcaaacta taatcgactc tagagtcgag
     7081 agaacgtttc atatgtacta accttatact ttcatacaat actatttatc aaagttcatt
     7141 aaaaaatcta tcaatagcct cgtcaacttc ggatcgagag atggttttaa cagtcgcttc
     7201 ttctgctaga gatgctacta tttgtttgcc gtatcgtttt ccgatgattc tcctatccaa
     7261 aataagagtt aaggaacgtt ggtattcacg tctcatactt cttcccaaag cctgttttaa
     7321 acgaataatg gccattggca attgataatc ataaaaggca tttttccctt cttgattcag
     7381 ttcttgatta atctttttcg tcaagggttc ttgaggattt tggaaaggaa gcctcggtac
     7441 aacttgaatc acaaaaggat ggcttgaaaa atcaactccc tcccagaaac ttgctgcacc
     7501 aagcaagatt tgttgttcac ctttttcaaa gcgtttcttt agctgatgaa catccccatt
     7561 tttatactgg gccaagtggc caactgtaag taaatccgat actgctagaa gcatgtcttt
     7621 agcggtaaag agaaccaaaa tcggttgctg gaaagcttga atttccacta gtaaagcagc
     7681 tacctctctg gcatagactt ctaaggaggt ttctgttacc agagggaaat ctttgaccat
     7741 aaccacttct tgttcctgtt ttccccgaga ttcaatcttg acaaatttgg cttcaggata
     7801 gcctaaaagg tctgccaaag aaaccctctg actaatctca agagtagctg atactcccaa
     7861 gacttggcaa ctctcaggaa gtaaagagga cagaagagta cggcctgatt ttgtagaaga
     7921 aatctgaatt ttcttttgac tcgtttcagt tacttcaagc cagtaatcac cttcagctgt
     7981 aaaatagcga accagctcat caaagtcttc tacttccaat tctgaaaaat actgatggag
     8041 attgtccaga gaatctaaga tatttttcct agatttgcca gactgaaatt gttctatcaa
     8101 gtagagacac tcaaagcgaa tactttctag tatccgttgt tgaaccctgt tttcttctcc
     8161 tactaaagcc ttatcaatta aatcgataat agattgtata tcgtaggtct cttgaagcag
     8221 attttctaga gctaacaaaa tcttttggac ttcatcaata atcagtaaac ggtcactgac
     8281 aaattcagga ttatcttcaa gtctggttac gagataggca tgattagtca ctaaaagctt
     8341 gcaagtctct gccctttctt gactacgttt ccaaaaatct tccgtcacaa ataagctctg
     8401 ggatgataaa ttcccatcat gacgaaggtc tgctagaaaa tgttggtaac ggtagagttg
     8461 cccgatttca tccaaatctc ctgtctctgt ctcagtaagc cagaccaaga cttgcatttt
     8521 aaagcgtcta aataagcgat tttcatcatt ttcctgcaag gaatgataaa aggcatccaa
     8581 cttcagataa ttttgtggtc cctttaagct atgaatatct gtatggaaca cttccttgag
     8641 gcgtttacct tcttcttcca tgatttgatt ttgaagaatc tttgtcggaa cactaagaac
     8701 aatttgtcgc tctttggatt gagataaagc gggtaagaga tagccatagg ttttcccaat
     8761 ccctgtcggc gcttgaatca gagagacagg ttcatctttc aatagcaagc caacctcttt
     8821 agcaaaactt tcttgttcct ccctcacttc aaggttcaac agagaaatat ttttagaaaa
     8881 gtcttgagat agttttcgtg gctccagaga agcttccgtt ttcttaaaat atagaccttg
     8941 aacttggacc aagtctggag aactcaggat agattggttg cgataagttt cctcaataac
     9001 caggtaggac tcatatagga gagcgtcagc catttccagc aagcgttcca agagaccttt
     9061 aggaagctgg gtcatctttt tccgtaaaaa aagaagtaat tctgctgtag cttgggcatc
     9121 tgaaagggct gtgtgtgcgt gtttaagagg aattcctaat tctcgacaca aaatcggcaa
     9181 actatatttt tccagttcag ggaaaaagac ctgggccaat tcgaccgtat caacacgagg
     9241 gtttcttagc tcatagcctt caaaaaataa attttccgcc aagagattag catcaaactg
     9301 aacattatgg gctacaaaaa tcccatcctc caccaagtca aatatttttc tggcaacttg
     9361 cgaaaaatca ggtgcttgcg ccagacgttg gtctgtcaat cctgtcagtt ctttgatatg
     9421 agcatccaag ggttcatgtg gattgacatc cgtcgtatag tgatcgacga tttctccgtc
     9481 ctcaatcacg acaattccca cttggataat tttagcctta ctacctgtgc tagttgcctc
     9541 taaatccacc acaacatagc gattaccaat cgttttcatt ataaaaaatt ataccaaaaa
     9601 aagggccatt tggcacctgc aaacatagga taattttcaa actcaagaac actacttttc
     9661 ttaaaaatcc catcgaatag agcattctag cctgctgatt tttgtaaaat agtgaagaaa
     9721 tacgaaaaat tgagagaaga aatgtttgca tcttccttct ctcaacgaat catgtatttt
     9781 atctaaccat gtcaggatcg tagtcataaa atcctgtatc aaggaaacgg tttttagggt
     9841 gaagtttacg aacttcttca tccagcaaga aggcttgagc atgactaaag ttgccctctt
     9901 gaatcaagct acgcgcttgg ataaagagtt ttgcaatctc aacaaagttc tgaccaggag
     9961 tgtagagccc ttctagtttc cagcgagtaa agccatgctc caccaattct gttaatttga
    10021 tcatcaaatc aaggtcattg ttggcaaaga tatgggtccc atgattatct tcaaaaatgg
    10081 aatagtggct ctctggatca cttggctcag ccaagaagag gtcacgttta tgcgtctttt
    10141 catcatcgat atgtgtaaag ttatagtagt tttgcaagag tggacgttta gaatgatgga
    10201 tgacgctagc accgtaaacc aaaacttcag caggaatttc caaaatctct ggcattttga
    10261 aaagttcagc tgatggaatt tcacgcgcca aaacagcctc agatgcgcca gccttttgtc
    10321 cccagaagtt aatctgacga ctgctagtta ccatggttga agcatcgtag atggtcttaa
    10381 atgaataacc atcgcggtta actacgtaaa agacgcctgc atccccaatc gtaatatagt
    10441 ctgtcttgat ttcttccaag aagtctaaga aaggcttgat acggtccatc atatcttggt
    10501 gcatgagagc attgaccgca acgatcaatt ccttaccagc atcatgaacc aacttagcga
    10561 tttcacgtaa ttggtcataa ctaaaggtcg ttggcagacg aagaccaaaa tctttctcac
    10621 cgacatagat acggtctacg ccagcttcga gtagttgttc aacttgttca atactttcag
    10681 cagttgctgt aatgacaatc ttttccataa gaaaaattat accacatttc tccaaaatca
    10741 gccatgcttt gaaaatgaaa agggacttta ttctttttgt aacctttctg taataattct
    10801 ctgccgaaaa aatgataaaa taggtatgta ctgttaagga gagaatcatg cccgtaagaa
    10861 aattacaatc ctatgaggta gactatcaag aagaattaaa ccagcagctt cctcattacc
    10921 aagcttatac acctgaagcg caatctgatg ccaatctcaa ggaaatccta ttttttatta
    10981 atatcgctgt tttttgtatc tgtattgcta tctttagttt tatcttttta gcattaaaat
    11041 tatcaactgc tcttgccttt gccgcagcaa tcggattcag cttacttgtt ttaaaagttc
    11101 aacggtctat tatcaaacga aaacgtagaa gataaatcca aaatatcgcc ccaattggag
    11161 cgatattttt attttttctt tttagatggt gtctgaatgg caatcttcac ttcaaagatt
    11221 gttcccttgg gtttattatc tttgacagta acagttcctt ttagagcatc tacaatttgc
    11281 ttggctaggg ataatcctaa accaaaacca cctttttgcc gggttctagc cttgtctact
    11341 cgataaaaac ggtcaaaaat tttcttttta tcttctgtcg aaataccgat tccattatca
    11401 gaaacaagta aataaagatt gcgatcggtc gccgagataa gaaaatcaat ttcaccatcc
    11461 tcctcagtat acttgacggc attatcgaaa agaatggtca tcagttgttt cagaagaagc
    11521 tgatctgtga caattgttcg atggatacga ttttcaaaac ggaagacacg attattttcc
    11581 gaagcaatca tctcatagtt tgtgaaagtt gtattaaaaa agctagttgg aacttctgca
    11641 agctccggct taatcccatc atctctccga gctaagttca gcaagcttgt cgttaaaaaa
    11701 cgcatatttc ggacttcttc caaactcgat gcaatgcttt cgctcacatc cataatggta
    11761 gcttctggct tacgaaaaag ggtctctaag cgattttgca aaactgcgag tggagttcgt
    11821 aactcatgac tggcattttc cacaaaagac tgttgcttct gcatactctc aagcaggggc
    11881 ctaacactga ccctagctag atagagactg gcaagtaaag acaaaatcca gaaactagcc
    11941 atcacgacca caatcaattg ctcatgcttt tgactagcct gctccaactg actggtatta
    12001 atcaagacag cagcatactt gatattggtt gaaaccgaac taatattggt ctccatcaaa
    12061 atcacacgat agatttcttc ctgcccatag ctattaaaaa cctgaatctg gtagatatgt
    12121 cctagttctt tcttttctaa cttaatctta tccaagccca aaaatcgatt tccagaaaga
    12181 agttgagtaa agtctttatc aaagagaatg acttccgtat tggaactgac attaggtttt
    12241 atttctactt tactagcgtc cgccctagca ttttctaaat ctttaatctc ttctgttgcc
    12301 ctatttatag ccagctgaat aactgcttga ggattttcac tcagtccatg aagcttatcg
    12361 tccaccgaag tataaagact cgaatgcatg acttgtaaaa taatcagagt cattgtagaa
    12421 aaaatcaggg tgaagacacc gaagttgcgg ataaaataac taaagtcatc cgcataccat
    12481 gtttttttaa gtttactgaa catcttttaa aagataccca acactacgca aagtttgcaa
    12541 attctctgca aaagtggttc cctttaattt cttacggact tttgaaacat agacttcgac
    12601 aaccgaaatc gttgtatcac tatcaaatcc ccatagacgg tcaaaaatct gcgtcttagg
    12661 caaaatcaca ttttgatttt gaaggaaata aactagtaag tcgaactctt tccccagcaa
    12721 ttcgacagga gtatcttcaa ctttaacggt attggttgat aaattaacca cgatattccc
    12781 ataagtcaag gtgttttcat taaacttccc tgaacgtttg agaagggcct gaatccgcat
    12841 tttaagttct tctaggtaga aaggtttggt cagataatca tccgctccca gttcaaatcc
    12901 atgtcccttg tcatccaaac tttccttggc agtcataatc agaactggtg tcgtaattcc
    12961 cttttcacgc aattctttta agacttggaa accatttttt tctggcaaca tcaaatccag
    13021 caaaatcaag tcatagacac cactctcagc ttcgtagaga ccttcttctc catcaaatac
    13081 ctgcataaca tccgcaaaat cgtctaaaaa gtcaaatact gaatttgaca gacctaggtc
    13141 atcctcaacc aataagattt ttatcatgag aaactcctcc ttattaaaac tattatacca
    13201 aatttgcctt aaaaaaaact caactctctg cattttacat gagatagctg agttttcttt
    13261 ttattttagg cttatttatg catttccgta ttgaagaaca actgcttcga ctgcagcttt
    13321 ttcacggcta atcaagtcaa cacgtgctgc aatttccttg attcccatac cgatgttacg
    13381 gctaagagca aggtcagaaa gttgcggctc aaagaactcc ttgtattccg ccaagcgttg
    13441 ctgagtctta aatacatgag caggaaggat aacaaagcta tcaaagctca tatctcctcc
    13501 aagggctgcc ttaatccaag cccagttttc acgcgcccaa gaccaagctg ttttctgagt
    13561 tgcttgatga gctaggaatt ggtaatacca agcagacaag tcctgtggtt tgaccacaaa
    13621 tttgtccttc caagaagtaa tcaggttttg gatattatcc gcatctgtac tgtatgcaag
    13681 agctgctgcc aactggcgtt taaagacagc atctgttgcg tgagtataag tatcaagata
    13741 aagtgctaac aagtctttag tctcatgatg tttcatctca ttaatcagaa cttgtgagcg
    13801 aatagctgct gggagtcctg caagattctc cttgtgtgtt gcgaagattt ggctagcgac
    13861 ttgactagct tctgcatcat ttgagcgaat catcatcgaa acagccagct gacgaaccaa
    13921 ttcatcctca tctgattctc cgtctttagc ttcaaaacca agacggtcat agttatgacg
    13981 agccaattta gcaaccagtc ctttgaaggc tgtttcagca tccgttcctt catcaataaa
    14041 gcgctcaagg gctgaaatca cttgagaaac agctgaaacc accagataag actcttcctt
    14101 agcaagttta tcaagaactg gaagcaagtc tgcataagaa atgtgccctg cctcagccaa
    14161 caaacgacgt tcttgaacaa tttgcagttt gcttgtgtta tcaagtgtct ctagctcagc
    14221 aagaacagct tctaacaagt ctccttgata gtcggtaata tagtgggcag tattttcagt
    14281 gttgagacga agagctcctt cattttcagc aagaagagct gcgtagccag ggatttcgat
    14341 actttcagtt tcgagtgtat caggcaagcc tttccagttg ctattgaggg gcaccaccca
    14401 gagacggttc ttgtcttcgt tctcaccgat gaagaattgt ttttgtgaaa tcttcaagac
    14461 atcattttca actttgacag taagaactgg gtaaccaggc tgttccaacc aagaatccat
    14521 gaaggctgcg acatcacgtc ctgacgcttg accaagggca tcccaaaggt cactaccaat
    14581 ggtgttgctg tattggtgtt tttcaaagta ggcgtgcaaa cctttagcaa aatcagcatc
    14641 tcctagccaa cggcgaagca tgtgcatgag acggcttcct ttggcataga cgatagcgcc
    14701 gtcaaagagt gtattgattt catctggatg tttaacttcg acgtggacag actgaacgcc
    14761 atcagtagcg tcacgttcaa gagcaagagg tactccacct gtttggaaat cttcaaagat
    14821 attccagctt ggttcgatgg tatccacaca gacgtattcc atcatattag cgaaactttc
    14881 attgagccaa aggtcatccc accatttcat agtcacgagg ttcccaaacc attggtgagc
    14941 caattcatgg gccacaacaa gggcaacttg ttgacggcta gcaaatgtag agttctcatc
    15001 gacaaccaag taaacttcac ggtaggtcac aagaccccag ttttccatag caccagctga
    15061 gaagtcagga agggcgatgt ggagagattg aggaattggg tacttaactc catagtaatc
    15121 ttcgtaaaac tcgatagagc gaacagcgat atccagtgag aaatcaagat ttgaaagtgg
    15181 atgtgctttg gttgagtaga cacctaccag ggtaccattt ttagttttag cggtcacccc
    15241 ttgcaaatca ccagcaacaa aggccaacaa gtaagaagac atgcgaggtg ttgtctcaaa
    15301 cttccagata cctgtttcct tacggttttc aacatcgatt tctggcatgt ttgacaaggc
    15361 caattcacct tctgcttggt caaagcgaag agagaggtca aaagttgctt tggcttcagg
    15421 ctcatccaca catgggaaag cttcgcgcgc aaaatggctc tcgaactgag tagacaagac
    15481 ctccttcttg actccatcaa ctgtataata ggaagggtaa atccctgtca tgttgtctgt
    15541 aattttacca gaaaaggcaa gaaccaattc aacttgacca gcctcagcca attcgatatg
    15601 aagggcttca ttgtcatggt caactgtaaa tggacgagct tgacctgcaa cttctacaga
    15661 ggtgatttcc aagtcttttt ggtggaggga gatgcggtca ctctgtgctt gaccagtgat
    15721 ggtcactttc ccagaaaaag tcttggtctc acgactcaaa tctaaaaata aatcataatg
    15781 ttcaggaaca aattgcttaa taaaatgttc aactgcttgc atagttttct cctattctaa
    15841 gtttaagagc tgctgctctt cttaaaacaa acttattata tcatattttg cttgagaaaa
    15901 aaggattgga cagcgatttc caaaactttc ttccttctaa tagtctacag tgggtagacc
    15961 ttgcgaaatt cttctaaaac aaccttgctt tcaggtgtaa aagtcagccc tacttcaccc
    16021 aaacagtctg tgaaaaagtc ctcatgaacc tggcgccaat aggcaagtga tttgtctccc
    16081 tcaccttcct taaaggcatg ttgcgcagaa acttgattga agagttcaac agaaaccttt
    16141 gtaatttcga caacgcagac agcctgattt tgactatcta aaatgacatc gaaggtccct
    16201 acttggggaa gtggttcgtc ttctagtaca tagaggtcat aggctgatgc tgttgctgtc
    16261 ttttctcctt taaacaccaa atccgctaaa aggtctggtt caactccaaa agcccaagca
    16321 tcgatttcat ctccgatcaa aggattgatt tgcttgtatt tattctacat ttcttgcggt
    16381 atcatgggta ctcctttgta attttttact ttcttctttt atgtgtttaa gatgatctgg
    16441 atggtcaatc tctaaatcaa aaatctctgg aatagaactg tagtggataa tgcacttgat
    16501 acccaactga ttcatttttt gtatgaaaga agtattcaga tagcctgcta cagcaaaatt
    16561 aatcttgttc tttcttgctt tatcctgcat atctcttagc atatctaaca ttattggact
    16621 ttccatatca tgccattgac tgtttctcat agtcgcaaaa acaaaggaag tcaaatcatt
    16681 cattccaact acaatctttg aaatgcccgt ttccagtata ctagataagt caaaatacgc
    16741 tgacggtaat tcaatcatcg ttccgacttt cccagtaaag ccatactgac gcaatactgt
    16801 aatagcttgt tttaattggt cggcatcatt gacaaaagga aaaataagag acagattggg
    16861 attggtttga taaacttctg taacgacatg tgattcagcc tgaaattcat ccaaacacgc
    16921 cagtaaacgc ctggttcctc tatagccaaa caagggatgc ccttcgtcaa aaaactctct
    16981 agtccccgct aaacaattgg cttctgtatt cgttaattca gaaaaacgat accaaacttc
    17041 cttatctaag taaaaggagc aaatagtatc aagataatct tttacaaatt gctgacaact
    17101 tgctaatatg atgttttgat taagctctct caataagtat tccccacgaa tcatgccgac
    17161 gtggtgaaat agttgaggat aaattttttc aagaattttt tcgccactaa gggcaagttg
    17221 atttctcata gccattcacc tcgtcttaaa agatacaata tcatatataa ttatatcaaa
    17281 atttcctcta gttcaaaagc ttcataaggt tcagataact catatcctaa aaattctgct
    17341 acttttttgg aagcctcatt atgagcatcc caaagtggaa acatatctct atttaaactc
    17401 tctagaatca ttgcagcacc aagcttttta gcaaatccat ttccttgttc gtttggtcta
    17461 gttgcaactt ccacttcaac tgctttacgg taaactaacc ctgaggaaat cccagcaatc
    17521 agttcattat ttttaagaat cacaaagcca aatccacctt ttaaaacaaa atcctgatag
    17581 gactcaaaat ccccctgtaa atcctgtgac cattcttccg tagaaaagca gttataaata
    17641 tgattatcaa taggcacaat attgtaacct tcctctaaat gagtaactag attatttaaa
    17701 aattcaactt gaaaatttgc cttatcttta aaagaatagc gagtaaaaga atttagcccc
    17761 acttttcgat gcagaaaatc ttgccaatta gtattttctg aaataataat cttataatct
    17821 aaaccatatt ttctaacaaa atcttcccaa aatctggaat ccaactcccc tgctaggtat
    17881 agaaaattcc caacatcata aaagcttgtt gtcctatcat tgtttcggta gacagttcca
    17941 atttgagatt taagaccata gagaaccata tttttcttcc atgttttaaa tagttccatt
    18001 atccctctac ttcaccttcc aattcatgta agaagtcttg tccagttctg gaaatcctaa
    18061 taattcagac ttaaccttca agactaatgg cgatgcattt tcttctgtaa tctcttgaat
    18121 atccatccaa atatatccaa gtgaatcatt cgcaccatca gacacagctt ccgaagtcgt
    18181 aacttgaggt gcactctcat tcatttcaac atcatacaag gccatgacat ggtgaaccat
    18241 aaaatttgtt aactcttctc tgacgaaaac atcgtagatt cgaggattag agtagcttct
    18301 aacagtaaat cccgtctctt ccataacttc tctagtcagc gtttccgtca gtccttcacc
    18361 aagttgctga ctgcctccag gtagatcata ccgatgttga taagggcctc tcgctttttc
    18421 aatgcagagt aacttcccat tttctaagca aacagcgtag actccaaagt gttttttgat
    18481 ttccatccaa ctcctcctac ttcaaagacc agccaccatc tattgtcaag atttgtcctt
    18541 gcatggcgct cgcttttcca cttgctaaaa aaagactaag ctctgctatt tcctctggct
    18601 caatccagcg cttgattggg gtttcactag ccacccagtc agccaaacca cctggttcaa
    18661 aatccgcagc ggtcatagct gtcttgactg ctcctggagc gatcccaaag acctgaatcc
    18721 cagcttcagc atagtctaga gccaactgct tggtgaagcc agccaaggca tgcttggatg
    18781 aagtataggc gtgaccacct ccacctgcta ggctagaagc aatggaacac atattgatga
    18841 tgattccctt tttattttcc agcatttgtg tcaaataata ccgagtcaac tctactggaa
    18901 taatgtagtt gatttcaaaa atctcttgaa tgtcctgcgc cgtttgttcc aacagtggtt
    18961 tgtaatcatc caaaactccg gcagtattac acaaaacatc cacctgaggg caccagtcaa
    19021 aaataggttc caagtccaag gtcaaatctc tctgtaaaaa gtgaaaatca ccctctaaga
    19081 gtggcttttc accttggtca actccataaa cttgatagcc cttctctaaa aagaggcgag
    19141 cttgagccaa tccgatccct gaactcactc ctgtaatgag tacacgttta gtcatgcact
    19201 tctacccaat ccgttgccaa aacatcacaa gctgtcgggc tccacatgga aaaaccttct
    19261 ccttctccag acacgttgat taggaaataa ggtgtcattt caagtgcaag cccattttgc
    19321 tcgatggtat caaagagttg gacatagttt tccgcacctc cccaaccagt tcgtacatat
    19381 tttctcttag cctttaaccc aggcaggatc tcttcaaatg tcatgttttt ctcctttaat
    19441 tctacattct tcatttaatt ataacaaaaa aaccgcttta aaacggcttt ttgactgtga
    19501 tttatttaca tcttcttcta cttacggcaa attattccct gcagcaagat aaatttcata
    19561 ccattctttt cttgttaagc taaagtttgc cgcttggcta acttctctca agtgcttagg
    19621 atttgtggta cctacaactg cctgcatttt tgctggataa cgcaatatcc aagaaatggc
    19681 aatagttgaa gaggttactc catatttaat agctaaacga tcaagtactt gatttaaagc
    19741 ttgaaatttc tcatttccaa caaaattccc tttaaaatac ccgaattgca agacagacca
    19801 tgcttgaatg accacatcgt gtaattggca atattcaaaa atgctgccat ctcgcatagc
    19861 tgcttgacta tcttccatat taacatgaaa agctgattca aatcctggag taaaagccgc
    19921 actcaattgt agctgattaa cagctaacgg ctgcttgaca tcttttttaa gcaactccat
    19981 catcatagga ttttgattag aaactccaaa atctcgaact ttaccttgtt tataaaggag
    20041 attaaaggct tctgctactt ggtcagattc catcaaagca tctggtcgat gaaggagcaa
    20101 gctatctaga tgatcaatct tcaatctttg caaaataccg tctactgatt ttataatata
    20161 gtccttagaa aaatcaaaat aggtaaattc ttcaatgcga atgccacatt tggactgaat
    20221 ccacatcttt tctcttaaat ctggacgatt ttttaggaca agacctaaca gttcttcaca
    20281 acgaccacga ccataaatat cagccaagtc gaaggcattg attccaacag aaagtgctgt
    20341 ttctgcaagc tcttcaactt cttttacaga cttatctttt attctcatca ttccgagaac
    20401 aatttctgat aattctttgt catcttgacc aagagttatg tatctcatca aatttttctc
    20461 ctttaatttc taacattctt cccttcatta taacaaaaaa ccgctttgca acggcttttt
    20521 gactatactt cactccattt tatcttctta aacccacgga acaagacaaa gattccaata
    20581 aagaggacag ctaaaggaat aacttttgta aggaaaacat ttgaaattcc catccactca
    20641 taataacgga gcagagaacc caccacaaga tgggcaataa tcatactgac aaatggacga
    20701 aagaccgctt ctttccaatt ccaaataccg ataactagcg aaatcgtaaa gacagacaaa
    20761 ctatcccagg gagccggaat ataaaaggct ccttcttgta tgaagcttgc cattcctaca
    20821 tatcctaaaa caactagaag aactatagtc ccaacaacaa tgtaagtgcc aattttcatt
    20881 ttaggagaat cttggactaa acttcttcgt aaaattgtgg ccacaagtcc aaatccaatc
    20941 agaaaaataa gaagttgccc taaaaatgtg agcaaattga ctgttaagag aggaccttta
    21001 gaaaaatcac ttagtagttg ataataacgt aataccgcca ggacaagaat tggcgtcaaa
    21061 agggactctt tgatagaact gcgaggtgct cccttgagaa tctctttcat tattttttta
    21121 ggattcttac ctagataatc ctctgcactc atgccatctc gttctgcttc tgagaaatct
    21181 agcatcatca aatagatctg ctctctgaga tagtcttcat catagagaaa tccagcaaga
    21241 ttaaaacttt cccacaactc ctcaaaatac ttttgattct cctcagaaaa ctcatgtagc
    21301 aaagcgcttg tttcttcgta atacttcatt ttcttcatgg tttaaccccc attcttaatc
    21361 ccttctactt tttgactcaa atcgtcccat tgttgccaaa agactgagac acgctcttct
    21421 ccttctttca ttaatgaaaa atacttccga tctggaccat ctggcgacgg gcgcatgtcg
    21481 cctcttatcc attgattttt ttctaacttt tgcaacaaag gataaatagt tcctggaacg
    21541 atagtatcaa atccagcctc tcgcaaagtc tgaaccaact cataaccata ccgctctttt
    21601 tgaccaatca tatccaagac acaaccttca agaacacctt ttaatagctg agtttctttc
    21661 atcacttctc ccttctaatc tattttgtaa tacctactag taacttcacc tatagtatat
    21721 cacttctaca ctagtttgta aagcataata gttaatactc ttcgaaaatc tcttcaaacc
    21781 acgtcatcgt cgccctaccg tatgtatggt tactgacttc gtcagtttca tctacaacct
    21841 caa
//
LOCUS       DBEJJE010000037        21612 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEJJE010000037 DBEJJE010000000
VERSION     DBEJJE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.37"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..232)
                     /locus_tag="ACL3F5_001452"
     CDS             complement(<1..232)
                     /locus_tag="ACL3F5_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HGR0515234.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQI"
     gene            complement(236..454)
                     /locus_tag="ACL3F5_001453"
     CDS             complement(236..454)
                     /locus_tag="ACL3F5_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0515235.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(1192..2823)
                     /gene="rlmD"
                     /locus_tag="ACL3F5_001454"
     CDS             complement(1192..2823)
                     /gene="rlmD"
                     /locus_tag="ACL3F5_001454"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0515236.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2897..3871)
                     /locus_tag="ACL3F5_001455"
     CDS             complement(2897..3871)
                     /locus_tag="ACL3F5_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0515237.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKGFGS"
     gene            complement(3945..4559)
                     /gene="pmp23"
                     /locus_tag="ACL3F5_001456"
     CDS             complement(3945..4559)
                     /gene="pmp23"
                     /locus_tag="ACL3F5_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0515238.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4559..5533)
                     /locus_tag="ACL3F5_001457"
     CDS             complement(4559..5533)
                     /locus_tag="ACL3F5_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0515239.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5541..6797)
                     /gene="glyA"
                     /locus_tag="ACL3F5_001458"
     CDS             complement(5541..6797)
                     /gene="glyA"
                     /locus_tag="ACL3F5_001458"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0515240.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6859..7290)
                     /locus_tag="ACL3F5_001459"
     CDS             complement(6859..7290)
                     /locus_tag="ACL3F5_001459"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515241.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(7292..7891)
                     /locus_tag="ACL3F5_001460"
     CDS             complement(7292..7891)
                     /locus_tag="ACL3F5_001460"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0515242.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFSKALDEKAVDHVYQLKRRP
                     RDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7878..8717)
                     /gene="prmC"
                     /locus_tag="ACL3F5_001461"
     CDS             complement(7878..8717)
                     /gene="prmC"
                     /locus_tag="ACL3F5_001461"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0515243.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPAWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDATDYLKDSGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(8717..9796)
                     /gene="prfA"
                     /locus_tag="ACL3F5_001462"
     CDS             complement(8717..9796)
                     /gene="prfA"
                     /locus_tag="ACL3F5_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0515244.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9806..10285)
                     /locus_tag="ACL3F5_001463"
     CDS             complement(9806..10285)
                     /locus_tag="ACL3F5_001463"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515245.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10275..10874)
                     /locus_tag="ACL3F5_001464"
     CDS             complement(10275..10874)
                     /locus_tag="ACL3F5_001464"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0515246.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10997..11179
                     /locus_tag="ACL3F5_001465"
     CDS             10997..11179
                     /locus_tag="ACL3F5_001465"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0515247.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11316..12689
                     /gene="mnmE"
                     /locus_tag="ACL3F5_001466"
     CDS             11316..12689
                     /gene="mnmE"
                     /locus_tag="ACL3F5_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0515248.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQETNRII
                     LLNKTDLPETIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12736..13671)
                     /gene="dapA"
                     /locus_tag="ACL3F5_001467"
     CDS             complement(12736..13671)
                     /gene="dapA"
                     /locus_tag="ACL3F5_001467"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0515249.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     IPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13727..14803)
                     /locus_tag="ACL3F5_001468"
     CDS             complement(13727..14803)
                     /locus_tag="ACL3F5_001468"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0515250.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15145..15217)
                     /locus_tag="ACL3F5_001469"
     tRNA            complement(15145..15217)
                     /locus_tag="ACL3F5_001469"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15182..15184),aa:Thr,seq:ggt)
     gene            complement(15317..15826)
                     /locus_tag="ACL3F5_001470"
     CDS             complement(15317..15826)
                     /locus_tag="ACL3F5_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0515251.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15824..15920)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15949..16380
                     /locus_tag="ACL3F5_001471"
     CDS             15949..16380
                     /locus_tag="ACL3F5_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0515252.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16462..16839
                     /gene="mscL"
                     /locus_tag="ACL3F5_001472"
     CDS             16462..16839
                     /gene="mscL"
                     /locus_tag="ACL3F5_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0515253.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16881..17975)
                     /gene="hemH"
                     /locus_tag="ACL3F5_001473"
     CDS             complement(16881..17975)
                     /gene="hemH"
                     /locus_tag="ACL3F5_001473"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0515254.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            18130..19350
                     /gene="pepT"
                     /locus_tag="ACL3F5_001474"
     CDS             18130..19350
                     /gene="pepT"
                     /locus_tag="ACL3F5_001474"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0515255.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(19393..20046)
                     /locus_tag="ACL3F5_001475"
                     /pseudo
     CDS             complement(19393..20046)
                     /locus_tag="ACL3F5_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            20044..20208
                     /locus_tag="ACL3F5_001476"
                     /pseudo
     CDS             20044..20208
                     /locus_tag="ACL3F5_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(20498..21596)
                     /locus_tag="ACL3F5_001477"
                     /pseudo
     CDS             complement(20498..21596)
                     /locus_tag="ACL3F5_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6256 a         4508 c         3981 g         6867 t
ORIGIN      
        1 aaatttgttt gctaatatct ctttcttctg attttgtttc aaggattatt gctacatcat
       61 tcatattttt aggtaaatac caaccatctg gcttatctga atatcccttg aagcctaatt
      121 gattaaaagt agttatttga ccagtacctt gattgatgtt ttcttcaact tcattaaagc
      181 ctaatacttc tcttgcataa tccctaactt gatcttctgt ccttaaagtc attttctatt
      241 cctcgtcact aaaattatct tcaaaactaa taatatcatt aggagtgcaa gataaagcct
      301 tacatattct ttctaaattc ttaaatgtaa ttggtttatc ctttcccatt tgtgccataa
      361 catttgttgt aagtcctgcc atagctatta catctgtttt ctttagtcct ttttttgcta
      421 actgtatcca taatggttta tagttaagtg ccataatatc cctctttttt tcttcattag
      481 atttatttaa ttatagcata aatattgatt tcattcaatc ttacattgat ttagtgattt
      541 gttttagaga atttgttgtg ttattccgtc cttattttgc cataaattgt tttaagtggg
      601 acctcttatc cttaccattt ttacctccta attttgagta taaaaaagac gatagagttt
      661 ttaatttcta tcatctgaga tttacatatt aaattttcat cacaaaataa gactctttaa
      721 agaatcttta aattcattgg tatgctaatt acaatatcca ttattaaaat ggatactata
      781 agcagcacac caactattta ttttttgagt tttaaacttt ggtagaagtc ttgaactcct
      841 tatatttaca taactatttg cctctataac tattatgaca cgaaaccaac aagcaagttc
      901 aagcacctcc atatctttat tcaaatgagg actaagatat tcacaaacat tatcataaac
      961 ttctttatct tttttcataa aagaggcata caacttagca aatttatcct aaaatttttt
     1021 gttgccttta tcaatcattt caacgctcct ttaaatataa aaatgatcct atcaatcttt
     1081 atattgagcc tattttctaa ttgatacctt gcaagaaagg aataatagct gttcctatac
     1141 caagtaggaa tgtaataaat gcagaaagtc atatactgtc attcttttct attaaatcat
     1201 tttgaagtgt ctcaaagcat ccatgatggc ttcttctttt tcaggtgtac actgtggaat
     1261 aatttgttta tcctttttag acttgttgta atgttctcgt aattctattc cacatttctt
     1321 ttttatctgt gcaatatata atgtcgaaac ttttaattca aatttattcc aaacatattc
     1381 tttgatttga gcatatgttg ctttgctctc cgcacttgtc aaatccatct catccagctc
     1441 aatttcaaca cttatgtgct tatcgacatc gagtttggac aaaagtgcta ccgtctcgac
     1501 gtgatgcgtt tgaggaaata gatccaccgg ctggactttc ttcaattcat atcccaactc
     1561 ttggtatagt ttaatatcac gcgccatggt tgcgacattg caggagatat aggcgatgcg
     1621 atcggctcct gtttgggcgc ttgctttgat aaagctttct gtcaagccct tgcgtggagg
     1681 atcaaccaag ataacggttg gttgaatccc atctttaagc caattcttca tagcattttc
     1741 agctgtgtca cagacatagt gggcgtttga aatattgttc agctgagcat tttttttact
     1801 attctcaacc gcttctggaa tcagttcaac accgtagact tctttgacat gcttggcgac
     1861 tgataaacca atggttccaa taccagaata agcatcaata accacgtcat ctttttttaa
     1921 ctctgcaaag tcaatggctg tttgatagag tttctccgcc atttcagtat tgacttggta
     1981 aaaggctggg ccagcgattt ggaagtcatt tcccaacatc tggtccgtaa tatagtcttg
     2041 accataaaga gtgcgccact ccttaccaaa aatcgcattg gtattctggt cgttgatatt
     2101 ttgcatgaca gacacaatct ctgggaactg cttgataact tgttcaatca attggtcaac
     2161 acgaaaaact tttggacgag ttgtcaccaa aacgaccatg atttgtcctg aatagtgacc
     2221 acgacgcacc acaagattcc gaatcaatcc agactgttcc ttttcgtcat aaggttttaa
     2281 atcaaaacga cggagcaggt ctcgaagagc tactacgact tggtcaatga caggatcctg
     2341 gataaagaaa tcttcaaggg gcatgaggtt gtgcgaattc ttacggaaaa atcctgtttc
     2401 caagacacca ttcactcgac gaacgggcac ctgcgcctta ttgcgatact tgactggatg
     2461 ttccatacca agcgtttcag caacttctac atctgcaatt ccagcaatct tgtagagact
     2521 gtccttgact tgcttggttt taaacttgag ctgttctgga taagaaaggt gtcctaaatc
     2581 cgcgattcct gaacgcaggt aagccaaatc tagatcttga ttacggtgtg gtgactggac
     2641 aaggtatttt tcaacttttc caaagccaat ctttttattg accttgagga cacgcatgag
     2701 aattttttca ctcggtaaag cattctctac aaaaaagacc aaaccatcta ccttggcaac
     2761 tcctgcccct tcatgggtca aatcaacaat ttcaacttct acaatatcat ttttctttaa
     2821 cattcttttc tctttctatt ggccgacaaa aaagacggca acgttacggt taccatccat
     2881 tataccatga aatttcttaa gaaccaaaac ccttgaagaa gttgacaagg gcttgccaga
     2941 gggagcttaa gaagttacca ccgtcctcta gcgccttatc cgcatcaaag ttaaggttga
     3001 tatttttaaa actgtcgcca gcttgtgata cgatgctttg tttaaggtca tttagggttt
     3061 tagtgaaatc tgcattgctg aggatatcac tctttgagag attcaaggca aaattgatga
     3121 tgatattgat ctggtttcct gttatgacct gatcaagttt gtaatttttt aaggtatctt
     3181 caacaatctt gcggatatct tcttctgtca gatttccctt gctttcttta gctttggcga
     3241 gtcctgactt gatatcagct agggcaacgt ttaatttatt agcatcataa cctgatttgt
     3301 ccttgttttc agcattgata tctgacaaag cctttagctc ttcttgagcc aaatctttat
     3361 tggcttgcgg caccttggct ccattagctt ctagcgaata gtagatccca gccaaagcac
     3421 tctcacctgt aactggaatg ggtgctgcta cagtgatttt ggcgtgttcc acacccaaag
     3481 ttacggctgc atttcggtac atatcctgag ttaccttagt gatgttttca ggtgtttcaa
     3541 tcttgacctc aagtggcgat ttgtcaccta gcttttgaat cttggctgat gaatacaact
     3601 gtaagctaga gtcattggcc acattcatga ttttagaata aacatcaggt gtcatggtct
     3661 tgagttcttt ggtatctgtt gaggcattgt agcccagttt tttaagagtt tgattttttt
     3721 ggtcttcaga tagggaagaa cctaggacat attcaggttg gacataggtt tcatcgataa
     3781 ctttttgaac atctgttgct gcatggacgc tattcatagc tgttactgcc cacaagatcg
     3841 cagcgctagt cagaaagagt ttctttctca tagggaattt cctcctttac ttctttagag
     3901 taatatatct atcttaaaga aaacttataa caaaaacacc tggtctagcc agatgttgaa
     3961 aagagagtga aacatttgat gatgtaaagg ttaagtcgta cctgtctaga ataataatag
     4021 tttcctccat ttacatagag ttcagcaccg tgaaaaatgg aaatggggtg aatataacta
     4081 taagtctttc cagtcctatt accaagcaag ggggcaacag tctcacgaga gtactgtttg
     4141 gctagagcca aggtattttc cttgccattt tgggcgataa aatcgatata ggcaggtcca
     4201 aaattatagg cttgaacagc tgtccagata tctacaccct tcttctgcgc cagatagaga
     4261 ttgcctgtca gagtttgaat gccttgccga atgctagagg cattatcatt gatggtgttg
     4321 gtggaaccac ttgcagactc actagactgc ataacatcgc cttcttttcc ttttgtttca
     4381 gtataaatca tagcaagcac aagctcttcg tttgctgggg tgtctttttc actcaatatt
     4441 tctcgcacca tgggttgata ggtcatgact tgtttgacat cttgatgaac gcggtaagct
     4501 ttatagccag caaaaaggaa gactgctagt acaagcactc ttcgaattcg tttaaacatt
     4561 atttactttg gatatcctcg atatttttga ttaagataga gtaggttcca ttttcgtttt
     4621 ggataaactc aacagactcg gcgtcttgat agacgttatt gggaacgatg agctcaattc
     4681 catttgataa ggagagtttt tggttttcaa atttctttaa ttggcgactg gcatcaattt
     4741 catcaaattg aacaggttct ggtacggctt ctttgacttg gtcaataaag ctcaaacgag
     4801 ccgtcagatt gttgtcaaaa aggtcattag ccaatttctc aggtgacaat tcattgcttt
     4861 cttctaggtt gttgaaaata gctgatttga ccttggattg aaattgaaaa tcatctgtgt
     4921 taaaagattc agcaattctc tgggctgttt tttccagttc cttgatagat tttttaggag
     4981 aaatcttagg agcgacagca agaagattat ctgaaaaata gttcaaaaaa gtcccgttgt
     5041 acttgattcg tttttcaatc aggtgatact tgcgactctg aagattgacc accaaggcct
     5101 catcagctcc cgttccaaat ccaggcaggt tattctgagt cagcttgatt ggattatcaa
     5161 cttctcctcc gaggtgggtc aaggtctccc gcagggcaat tcgcaagaaa gcgaaatgtt
     5221 ctacaccttc tttagaaaat tgaacaaaaa tcaagtcatt ggtcttgaga ttttcagaaa
     5281 tgctaaactc ctctttccag agattagcca gcgttactga tgtctccaac aaatcgtctg
     5341 taatatgatt gaagaaggga ttttcttctt cgaaaatccc agtcttggct tcatctgaat
     5401 acacatgttc aattttttta cgtaggtatt cttcgatttt tggagtaata ttgagaaact
     5461 tatctgctaa gaacagctcg gtatcatccg gactgaactg gtgaataatg gctttcttaa
     5521 tataaatatc cataaaagtt ttagtcctcg tataatggga aggcatctgt caattctttg
     5581 actgcacttc tcacttcttc taatacagcc tcattttctg aattcttaag ggttttaatg
     5641 atgagttcag ccactttgcg actttcttct tcaccaaatc cacgtgcagt aatagctgct
     5701 gctccgatac gaatcccact tgtcttgaat ggcgacaagg tttcgtaagg gattgaattt
     5761 ttatttaggg taatattgac ttcatccagc aagttttgag caacttttcc gttttctaca
     5821 accttagtca catcaacaag gaagagatgg ttttcagttc cacctgaaat aatacggaaa
     5881 tcagggtctt gcaagaagac atctgccata gccttgctgt tcttaattac attggcagca
     5941 tattccttga aggctggatc caaaacttct ttgaaagaaa ctgctttagc cgccacaaca
     6001 tgctctaaag gaccgccctg aatacctggg aaaatagctg aattgatttt tttagcaagt
     6061 tcttcgtcat tggtcaaaat caaaccacca cgaggtccac gaagggtttt gtgggtcgtt
     6121 gttgttgtga tatgagcgta tggaactggg cttggatgaa ggccagccgc aaccaaacca
     6181 gcgatatggg ccatgtccac catgagcttc gcaccgacag catctgcgat ttcacggaat
     6241 tttgaaaaat cgataatttg agaatatgct gaagcaccag ctacaatcag ttttggtttt
     6301 acttcttggg cttgtttcaa gatagcatca aagtctaaga gttccgtttc aggatcaaca
     6361 ctataagaaa caaagttgta ggtttgacca gagaagctaa caggagcccc atgagtcaaa
     6421 tgaccacctg atgccaaatc cattcccata accgtatcac ctggctcaat caaggacatg
     6481 taagccgcac agttagcttg gcttcctgaa tgtggttgga cattggcaaa tttagcaccg
     6541 aaaatttctt ttgcgcgttc aatagcaaga gtctctacaa cgtctactac atcagttcca
     6601 ccataataac ggcgtcctgg gtaaccctcg gcatatttat ttgtcaagat agacccttga
     6661 gctgccataa cagccttgga aactacgttt tccgaagcaa ttaactcgat attattttgt
     6721 tggcgttctt cttctttggc aatagcattc cagagatcag catcatatgc tttaaaatca
     6781 tctttgtcaa aaatcatagg tcttctcctt tattgtgtga ctagtccatt agtttgattt
     6841 tacaataaga aaatcaaact aacagatgcg aataaaccgt ttctgcattt tatcacaagt
     6901 atagccaact ttttcataaa atgcatgagc acccagacga tgattggcag aatttaagcg
     6961 gataaaccca taaccacatc tttttgcttc ttcttccaac ccttgtagta aacttttacc
     7021 aataccttga ccttgcgctt gaggtgaaac tgctaaagct aagatattaa atcctgcttt
     7081 agaatagagt gattcgtaaa cttcagcgtg gacatatcca agtaagacat gattagctgc
     7141 atcctcatag ccaagtagga aatgatggga atcctgagac agtctagcta gttggctagc
     7201 cgtttcctct ggactaaaag tataacccaa agcctcttgg ttgatgtcac atatcgcttt
     7261 cacatctgtt tcttgcaaat ctcttagcat ttcaagcctc ctcaaaagaa atctctggca
     7321 accgagcaag aatatcttct cgtttaattg cgccttggcg taagattttc accttgtctc
     7381 cagacaaatc cacaatagtt gaatcctgtc cagttagaaa agcatcgtct tccagaccca
     7441 gaacctcttg gtcaaaatcc ttcagaattt gttcaaaggt tacaccactt gcctgacctg
     7501 agatattggc agacggccca atcaagggac ctgtctctcg aattaaatcc agtgtgatag
     7561 ggtgactggg catccgaaat ccaatagttg caaggtcaga atttacccaa tagggaactc
     7621 ggtcattggc ttcgagaata atggtcaagg gacctggcaa aaaggtctct acaagttttt
     7681 gtagataagc tggctgattc tttgaaaagt gcaagatgtc ctcgaaagag gcgatattga
     7741 gattgagtgc cttatctcta ggacgacgtt tgagttggta aacatggtca actgcttttt
     7801 catctaaggc cttggaaaaa agaccataaa ccgtctctgt aggcagaatg acagctccac
     7861 cattttccaa ctcttgtcta atcctgtcca tcatcaacca cgaccatcct atcttgacca
     7921 aattggtcct tgagtgttcg aactcttttt tcaggaagat gtttcctaaa aagttcggga
     7981 acactttgac cttgcttgta tccaatttca aggtaaatct taccactatc tttgagatag
     8041 tctgttgcat cttccgcaat tctacagtaa atagctaggc catcctcgtc tgcaaagaga
     8101 gctagatgag gctccgaatg caaaacattc aagcctacct ctgactcatc ttcacgagag
     8161 atatagggtg gattggatac aattatatca tatttttcag aaatttctgc aaaacaatca
     8221 gattttttaa aaaatatatt aagattttga tcgctagcat tctctgatgc aagctctaag
     8281 gcctcttgag aaacatctgc tgctgtcact gaccaagctg gtctattttt tgctagagcg
     8341 agagcaatag ctccactacc tgttccaata tccagaactg agagattcgt ctcaagattt
     8401 tcagttagaa taagctccac taactcctct gtttctggac gaggaatcaa aacccgttca
     8461 tccaccttta aatgcattcc ataaaaatct gcctgtccaa tgatgtactg agctggcttg
     8521 tgagctgcta gttgctggta aatatcttct acaaattgtt tttcttcctc tgttgtcacc
     8581 tcctgctgga gggcaaaaat aaagtctgta aaagatagat ttttcagact acgatagaca
     8641 aaagagaggc tttccgcttc ctctccttgt cttatcaact cttcttcaaa atttgaaaat
     8701 aattgagcta atttcattat ttgtttaatt cttctagttt ttgtgtttgg tcataaagca
     8761 ccaaggcatc cacaacttcg tccaatttac cagacaaaat cgtatctagt ttttggaggg
     8821 tcaagccgat acggtggtct gtgacacggt tttgtgggaa gttataagtt cggatccgtt
     8881 ctgaacggtc accagtaccg attgtcgact tacgctcagc gtcttgttca tcctgagcaa
     8941 tctgagcaaa gtggtcagcg acgcgtgcac ggataatctt catagccttc tcgcggttct
     9001 tctgctgggt acgttcttcc tgcatctcaa ccttgatatt ggttggcaag tgaacgatac
     9061 gaacggcagt cgcaacctta ttgacgttct gtccaccagc accagaggcg tgatagatgt
     9121 cgacacgaag gtcttttgga tcaatgtcgt attcaacctc ttcaacttct ggcataacaa
     9181 gaactgtcgc tgtcgaagta tgaacacggc cttggctttc tgtcacagga acacgttgca
     9241 cacggtgggc acctgattca tacttaagct tagagtatac agactgacct gaaaccatag
     9301 caaccacttc tttaaaacca ccgacaccat tcatagaggc ttccatgact tcaaagcgcc
     9361 aaccttgggc ttccgcatac ttttggtaca tagttagcaa atctccagcg aaaagtgccg
     9421 cttcgtctcc accagctgct ccacggattt caaggatgat attcttgtca tcgtttggat
     9481 cctttggaag gagcaaaatt ttcagttttt cttcatattc ttctttttca gccttggcat
     9541 ctttgagttc ttgcttggcc atttcttcca agtccgcatc tccgcctgat tccttaatca
     9601 tctcttcggc atcgacgata ttttgaagga cttgtttata ctcacggtag gctattacgg
     9661 tgtcacgatt ggaagcttct tcttttgaaa gctccataaa acgcttggtg tctgaaacga
     9721 catcagggtc actcagcaat tctcctagtt cttcataacg gtcttctaca gcttgtagtt
     9781 gatcatagat gttcattttt tctccttatt tctcaattgt taaatcatag attgctacta
     9841 cttcattctc ggatatttcc ccagtttctt taaatccata actgagataa caaaatcttg
     9901 cctgttcatt ttctggttca taagacaacc aaagtttatt gcttaaacct gctggcgctg
     9961 ttcgaacata gtctagtact ttatccataa ttggtttaaa atatccttga ttttgaaaat
    10021 tcttatcaat cataaaacga aatagtaaat aatttccact actaattccg atctttttat
    10081 cataagctat catcacaaaa cctataatta catcattatc ataaactgcc aatggagcta
    10141 caaaatctcc atttttagtg tagacgtatg cttcagctaa actaattgcg ttggttgcaa
    10201 tgaattgttt ttgatattcc ttgacatcca aatttaaaac atcaaaataa ttttccattg
    10261 taacatctct tagttcaatt gtcatagttt tgctccttgt tagaggttat cattggcgca
    10321 aaataatgtt tacggcaaac cgagatatag gtttcattac caccaatctg gatctgttct
    10381 ccatcgtaaa cgggcagtcc atcctgtgtt cgcaacacca tggtcgcctt tttcttgcaa
    10441 tactgacaga tggtcttgat ttcgtcaatc ttgtccgcta aaagcaagag atatttggaa
    10501 ccttcgaaca attcattgcg aaagtcattt ttcaagccaa aagccatgac gggtatgtct
    10561 aactcgtcca caacacgagc taggtcgtaa acatggtggc gtttaagaaa ctgggcttca
    10621 tcgaccaaaa cacagtaagg tttttctggt aggtctcgga tatagccaaa gatatccgtt
    10681 gtttcctcaa tcgcaagggc agggcgtttc atgccaattc gactcgacac atagccaaca
    10741 ccgtcacgcg tatccagagc cgaggtcata atgacaacac cttttccttg ctcctcgtag
    10801 ttataggcca ctttgagaat ctcaatcgtt ttaccagagt tcatggtccc ataacgatag
    10861 tacaactgtg ccatgtttct tgcttcacgt ccatttctaa atttttgcta cattctagta
    10921 tatcataatt ttcttaagct ttaaacggca aaatgtggta aaatggaaga aatcaaaact
    10981 agtggaggaa gctattatgc catttgtacg catcgattta tttgaaggac gcacgctcga
    11041 gcaaaagaaa gctcttgcta aggaagtaac ggaagcagtt gtccgcaaca ctggagcccc
    11101 tcaatctgct gtccatgtca tcatcaacga catgccagaa ggaacttact tcccacaagg
    11161 ggaaatgcgt actaaataag ctagcttaag cagaattgct taggcttttt caatctccaa
    11221 gtagcattca ttgaagaaat atcctaaatt tgttacaatt tgaaaagaaa cttggagaat
    11281 ttccaagaaa agagctatta attaaaggaa acattatgat tacacgtgaa tttgatacca
    11341 tcgctgctat ctctactcca ctaggtgaag gggctattgg tattgtccgc ctgagcggaa
    11401 cagacagttt tgctattgcg caaaagattt ttaaaggaaa agacttgaac aaggttgcca
    11461 gccacactct caactacggt cacattattg atcctctgac tggtaaagtc atggacgagg
    11521 ttatggttgg ggctatgaag tctccaaaga ccttcactcg tgaggatatt atcgagatta
    11581 acacccacgg tgggattgcg gtgaccaatg aaattctcca gctagctatt cgtgaagggg
    11641 ctcggttggc agaacctggt gaatttacca aacgtgcttt tttaaacggt cgcgtagact
    11701 tgacacaggc agaggctgtg atggatatca tccgtgccaa gactgacaag gccatgaaca
    11761 ttgcggtcaa acaattagac ggctcccttt ctgacctcat taacaatacc cgtcaagaaa
    11821 tcctcaatac acttgcccaa gttgaggtca atatcgacta tcctgagtat gacgatgttg
    11881 aggaagccac tactgctgtt gtccgagaga agacaatgga gtttgagcaa ttactaacca
    11941 aactccttag gacagcacgt cgtggtaaaa tccttcgtga aggaatttca acggctatca
    12001 ttggacgtcc caacgttggg aaatcaagcc ttctcaacaa cctcttgcgt gaggacaagg
    12061 ctatcgtaac agatatcgct gggacaacac gagatgtcat cgaagagtac gtcaacatca
    12121 atggtgtacc tctcaaattg attgatacag ccggtattcg tgaaacagat gacatagtgg
    12181 aacaaatcgg tgttgagcgt tcgaaaaaag ccctcaagga agccgacttg gttctactag
    12241 tgctaaatgc tagtgaacca ctaaccgccc aagatcgcca actcctagaa atcagtcagg
    12301 agactaatcg cattattctt cttaacaaaa ctgacctgcc tgaaacgatt gaaacttcgg
    12361 aactacctga agatgtcatc cgcatttcag ttcttaaaaa tcaaaacatc gataaaatcg
    12421 aagagagaat caacaacctc ttctttgaaa atgctggttt ggttgagcaa gatgctacct
    12481 acttgtcaaa cgcccgtcac atttccttga ttgagaaggc cgttgaaagc ctacaagctg
    12541 ttaaccaagg tcttgaacta gggatgccag ttgacttgct tcaagttgac ttgacccgta
    12601 cttgggaaat tctaggagaa atcactggag atgctgctcc agatgaactc atcacccaac
    12661 tctttagcca attctgttta ggaaaataag aaaaatccat gatccttcat tcggtcatgg
    12721 attttattgt ctttattagt aatctggtct taagacccct gttacagttg ccttagttgc
    12781 ttcgtagtcg ccatctacga caaccttgat aatgcgtttg gcatcttctt ctggtgctgg
    12841 aataagaggt agacgagtgg gtccagcttc aaatcccata tagttaagaa ctgccttaac
    12901 tggagcagga cttggataag agaagagagc attaacctta ggaatgaatt tacgctgaat
    12961 agctgcggct ttcttcatat cgctttctgc aatggcagta aacatctcgt gcatttcatc
    13021 cccatttgta tgagaggcaa cagaaataac cccatccgcc ccaaggttca tggcatggaa
    13081 agcatctcca tcctcacctg tataaatcaa gaactcttca ggcttgtgct caatcaagta
    13141 agccatatta gccaagctag tacattcttt gacaccgata atatttggat ggtcagccaa
    13201 acgaagcatg gtttctggag tcaattcgac aactacacgc cctggaatgt tatagataat
    13261 aattggtagg tcagaagcat ctgcaatagc cttaaagtgc tgatacatcc cttcttgaga
    13321 aggtttgttg tagtaaggaa caatagcaag cccagctgcg aaaccaccaa attccgctac
    13381 ttctttgaca aactcaatag agtcacgcgt atcattagta cctacacccg caatcaaagg
    13441 aacgcgtcca ttgacaacct tttgtacagc cgcaaacaac tccaactcct catcgtgggt
    13501 caaagttgga ctctcagcag tcgttcctgc gagaagaatt ccatccgtat gatgggccaa
    13561 taaatgctca atcaaggctg gaatagcatc aaagttaatg gaaccatcct catggaaggg
    13621 ggtaataaag gctgtaatga ttttacattt ttttaaatct tgataagaca cgaaaacacc
    13681 tctctatttc aaagaaggag ttcatctgaa ctcctaaacg atatgactat tttaattcaa
    13741 atttcaattc ggctgttgga cgaaccaatc cacgttcatg aagagtttca gcaatctgaa
    13801 ctgagttcca agcagcacct ttgagaaggt tatctgaaac aacccacatg tgaattcctt
    13861 tttctgcatc caagtcttta cggatacgac caacaaaggt atcacgcgaa ccaactgcat
    13921 tgatagcttg aggatagatt tgatgagcta catcatcttc aagaacagca cctgggaagg
    13981 ctgcgatagc tgcttttact tcttcgattg gagccacttc ttttgtttcg atataaacag
    14041 actcagagtg agctgacaag actggaatac gcacacatgt tgcagatact gcaatgctat
    14101 catcttccat aattttctta gtttccttgg tcatcttcat ctcttcgtac gtgtaatcat
    14161 tatcagtgaa aacatcaatt tgtggaagag cgttaaaggc gataggataa tgtttcttgt
    14221 caccacctga aggcaagatt tccgcatgca aatcacgtgg tttcacacca tcattcaaga
    14281 cttcacgaag ttcacgttgt gtctcaagaa ttgctcccat accagcacct gaaacggctt
    14341 gataagttga aacaatgata cggtccaagc cccatttttg gcgaaccggc tcaagagcca
    14401 ccatcatttg aattgttgaa caattagggc aggcaatgat tccgttgtga gcatcaagtg
    14461 catgagcatt gacctctgga acaaccaaag gaacatctgg attttgacgg aaataagatg
    14521 tattatctac tactaccacg ccagctttta ctgcgtatgg tgcatactta gctgatgtag
    14581 aactacctgc tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca gtcgtttctt
    14641 caattgtaat atcttgatct ttaaatttca atgacttacc tgctgaacgt gcagaagcaa
    14701 ggtaacgaat tttatcgatt ggaagtgttg attcttccaa catttttatc atctgagcac
    14761 cgacagcacc tgtcgcgccg actacagcaa ctgtatatcc cataaataac ctctttcgga
    14821 attttctaaa aatttctata atagaagtat tatactactt tttccatgaa ttgcaaagct
    14881 ttttcatcat tttttggaaa ataaaaatcc cagtcgctag actagggact aagaggcatc
    14941 ttcatgtgat gagcaggttc acacaactca tcaaggtccg ctcctgcgtt atgacctcct
    15001 tatgctcaat agtagtccga agactaccta tcgactcatc gcatattcta tattactaga
    15061 gatacttgat tttgtcaata agaaattttt tcgatcgagt ataacaaaaa actctcgtat
    15121 tcaagagttt ccctatacat atcatgctaa ttgccgggat tgaaccggcg acctcatcct
    15181 taccatggat gcgctctgcc aactgagcta aatcagctta cttaagaagt atactatatt
    15241 cagaaaaact tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta
    15301 cctagcttat cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa
    15361 tcgccccaat aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga
    15421 atggtaattc tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga
    15481 ggattgaaaa gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa tccttgctat
    15541 attttgcaaa aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa
    15601 agacatctag cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga
    15661 tgatgtactt aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat
    15721 aagcaccata gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag
    15781 cgacgattgc aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg
    15841 cggttgcccg cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgctttattc
    15901 aaccctacta gtatagcaca atagcctgct ttatgctata cttaacacat gaaaattcct
    15961 attcaaaaat tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact
    16021 ctagtttcga ttctctcacg actagtcatt tatcaactaa gtcatcagga actcctggct
    16081 actgccctag caaatattat cggtatccta tttgccttta tcacaaatga tacgattgta
    16141 tttaagcaaa aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt
    16201 tctacttttc tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatc
    16261 atagggcaat tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca
    16321 caaatattca ttattatcat caattatatc ttgagcaagg tctatatttt tagaaaataa
    16381 tgctccattt atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg
    16441 aaacattgaa aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat
    16501 gttattgacc ttgctgtcgg tgttgtaatt gcctctgctt ttggtgctat cgttacttca
    16561 cttgtaaacg acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtt
    16621 gaacgtatcg ctcaactttc ttggcatgga gtcggctatg gtaacttctt aagtgctatt
    16681 atcaatttta tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca
    16741 cagaaactga ctggcataaa ggaagaaaaa actgccgaaa aaaaaccaac cgaattggaa
    16801 gtccttcaag aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc
    16861 aaagctaaat ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt
    16921 ttgataagat aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca
    16981 aattctggca tttgtaaatc ttcagattca gccaaaatgt tttttgtctc gtctgaagga
    17041 actaactcat caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg
    17101 actctaactg tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga
    17161 cgatggtagt ttaccccaaa ttcctgacat aaatcataac attccacatc attgtcaaac
    17221 aagacctcaa tatgctcact gatgaaacta ataggtacaa aaatataatg gtctggatgt
    17281 tctgtctgtt ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca
    17341 ctctcactct gccaagtgtt agtatattgt tttgaactca agcccagttt ttcagcgact
    17401 agcttgctat tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaata
    17461 ggcacactat gggctgaaaa gatgacttta aagctgtctt gctttacttc ttcttttaaa
    17521 atcttagcaa tttcatctgc ccaatagttt aagagcgctt cttcctgata ccagtcctta
    17581 atgaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag
    17641 aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt
    17701 tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat
    17761 tcattcccca gcctagcttc taccaaggca acctcttgac gggtaatttt ttgcagaggc
    17821 gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc
    17881 accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt
    17941 gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat
    18001 caagtttatt ttatcattaa ttcatcgata agtaaacgct aacatagggg cattctcaat
    18061 cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg
    18121 agttttttta tgacttatcc aaatctcttg gaccgcttct taacctatgt taaggtcaac
    18181 acgcgctctg atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca
    18241 acaaatgtcc taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg
    18301 aatggttttg ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt
    18361 tttatatcgc acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt
    18421 gaaaactacg atggtggtgt gattgaacta gggaattctg gtttcaaact cgacccagct
    18481 gacttcaaga gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaagc
    18541 ttgctaggtg ctgatgacaa atcaggaatt gctgaaatta tgacagccat tgaatatcta
    18601 actgctcatc ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa
    18661 atcggtgttg gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact
    18721 gttgatggtg gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa
    18781 ttgcatttcc aaggccgtaa tgtccaccct ggtactgcca aagggcagat ggtcaatgcc
    18841 cttcagctag caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact
    18901 gaaggttacc aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggcgcgt
    18961 gcaagctaca tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg
    19021 caatctatcg ctgataagat gaatgaagaa cttgggagca accgtgtcac tctcaacttg
    19081 acagaccagt actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt
    19141 gctaaagccg ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccgaggtgga
    19201 acagacggct ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc
    19261 gaaaatatgc acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat
    19321 accatcattg gcatcgtacg tagcttataa aagctaaaaa gacgaggtag ctcagctact
    19381 tcgcctttct ttttattcta ctggtttttc ttgatttcca gtagttgtag aagattctgt
    19441 tgttttattt tctgaagttg attcagcagg tctagaatct cttgtattgc ttggtttgtt
    19501 ttcgtcgcta gcagtttcaa tgttagattc tgcagttgcg tttggttggt tctcagcact
    19561 ggtgttatca ccatttgctt cagcatttct tgctggactt gtttcttcac ttgcgctagc
    19621 ttttgactgg atttgatgat tcaaaactag aatagctttt gtcgattcaa gtaaagctgt
    19681 tttgtcttta ctcttagcag aaagttgatc taataatgca tccaccttat caaagtccgc
    19741 atcagatcca ttattacttt ctaaataaga gtgaagcgac atgagaatat cgtagagttt
    19801 ttgatagagt acaagtgtct gaggatcttg ctcagcattt tccttttctt gttgaagggc
    19861 gctagcgata cgagtcaaga catcttttac ctgactgttt acttcatcca agtctgcatc
    19921 agccttgttt gtggcagctt ttagattttc tacttcttct gccaaggatt gtctgattcc
    19981 ttcttcatgg atttgttcca agagttgatt tgccttgctc aaaagacttt ctacttcttc
    20041 cttgctatct gtcgcagatt attggttgct atctaccatg tattcctaaa acaggagagt
    20101 tataatccaa gattacaagg ccttacagaa ataagaaatc cagataagac aatgtccgtc
    20161 caagacgcta ttcgcttcgc acagcagcgc ggattcaata tgctttaatt ttaaagttta
    20221 ggtgtcaaga cctcttttta gtgtgcccaa aatttagaga agtaatcaat caactaactt
    20281 ttattttttt caaactttca gtaaactgac ctaaagctaa ctcaatctgt ctttgttcga
    20341 taggcttgtc tttgtagatg cttctgctat cagctagaag ttgatctact tttgccaaga
    20401 ctgccttctc atcaaaagtt ccaggtggat agttggattg cagggatgga atcttgtttt
    20461 tcaaagccgc ttcatatccc ttagtttgaa ccttgatgta gtgattgtgg tcgccatgag
    20521 gaatcacaaa accttctgaa tcttcactta taattcgatt ggcatcaaaa ccatgaccat
    20581 cttcttcctc atggtggaca tgtagtgacg gattacttaa tacagaacta gaagaacttc
    20641 ctacctcttc cgtgttagag tgtgatgggg gattgttaag agatgactta ggaatatagt
    20701 gatagtgatc cccatgtctt actatataag catcacctgt atctctgaca atatcattag
    20761 ggttaaagac ataaccatca tctactgcag aaacaccatt attcggtgtc accggcaaag
    20821 attgactgag agctgtagta ttccctgata attatacttt tgcgactgct aattcacctg
    20881 ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact atcgtagatt
    20941 gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac aatgatttag
    21001 aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc ggtagtataa
    21061 cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc tttaccatgt
    21121 tcttgttttt ggcgattgat ttcatctttt gttcgtacat tttctgcatg agcttgatct
    21181 ttaaggtaaa cataatactt tccatctccc ttaataatat atcctccctt aacctaactg
    21241 acgatatctt gatctttcgg ctgatagttg ggggctttca ttagtagctc ttcactaaag
    21301 agcgcatcaa aaggaacttt accattatag tagtgataat gatcgccatg agaagttaca
    21361 taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc tttttgacta
    21421 acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt tacatatgaa
    21481 acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata aacacacaga
    21541 cttaaggaaa ggataacaac agatccagct gctatatatt tctttttaaa tttcataatt
    21601 acctcatttc ta
//
LOCUS       DBEJJE010000038        20004 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEJJE010000038 DBEJJE010000000
VERSION     DBEJJE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.38"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            29..883
                     /locus_tag="ACL3F5_001478"
     CDS             29..883
                     /locus_tag="ACL3F5_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HGR0515256.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLYNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            complement(928..2793)
                     /locus_tag="ACL3F5_001479"
                     /pseudo
     CDS             complement(928..2793)
                     /locus_tag="ACL3F5_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(2780..3145)
                     /gene="mobC"
                     /locus_tag="ACL3F5_001480"
     CDS             complement(2780..3145)
                     /gene="mobC"
                     /locus_tag="ACL3F5_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGR0515257.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(3155..3514)
                     /locus_tag="ACL3F5_001481"
     CDS             complement(3155..3514)
                     /locus_tag="ACL3F5_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR0515258.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     IDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(4319..6817)
                     /locus_tag="ACL3F5_001482"
     CDS             complement(4319..6817)
                     /locus_tag="ACL3F5_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spaf_1101 family AAA-like ATPase"
                     /protein_id="HGR0515259.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFIGVKNINSIEGSRKKLLADFNCEPNFLLDNDSHEIDSLGKN
                     NLWLKGGKISFKMFQEALFDYNVSVSLCKPSFKQKSYIKGLYIENRGENRSFLAGDKL
                     KKDKDFFLTFSPSMNCLIGGRGTGKSTLIDMLQFVLSQDCDKQSKLEFLCNHANAFVL
                     YVLEETEYIIEVSLPDVKQENKDNILQYYGQNRENKFGYPYRFNSDTIKEWTRSQYTT
                     VYKVEGNHFKLVDKTRILEKMFDRRYSVNELVKTADGEKITEFISNLMIKNKKLPRPD
                     YGLRTQTLKSFEVKLKELDEYLKQQKQLILKIIEDFNETQIGKLRICYEQIDRWEEPH
                     FENYLFKNNRSSFDNYRISMQDVADVLYLIYRELGMKEFVKVIVRQNIPNKYFMLLKS
                     ISEDNFAKQENNWRDKSEINEYNITHLKKSIYSLIENSSLLNEFKRVLKEHVANERLF
                     LEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDN
                     LDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGY
                     VSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(6845..7606)
                     /gene="pezT"
                     /locus_tag="ACL3F5_001483"
     CDS             complement(6845..7606)
                     /gene="pezT"
                     /locus_tag="ACL3F5_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR0515260.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(7606..8082)
                     /gene="pezA"
                     /locus_tag="ACL3F5_001484"
     CDS             complement(7606..8082)
                     /gene="pezA"
                     /locus_tag="ACL3F5_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR0515261.1"
                     /translation="MIGKNIKFLRKTYDLTQPEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(8527..8982)
                     /locus_tag="ACL3F5_001485"
     CDS             complement(8527..8982)
                     /locus_tag="ACL3F5_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515262.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(9257..10996)
                     /locus_tag="ACL3F5_001486"
                     /pseudo
     CDS             complement(9257..10996)
                     /locus_tag="ACL3F5_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            complement(11159..12043)
                     /locus_tag="ACL3F5_001487"
     CDS             complement(11159..12043)
                     /locus_tag="ACL3F5_001487"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0515263.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKTRNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(12155..13009)
                     /locus_tag="ACL3F5_001488"
     CDS             complement(12155..13009)
                     /locus_tag="ACL3F5_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0515264.1"
                     /translation="MLGAIIGDIVDSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(13067..13825)
                     /locus_tag="ACL3F5_001489"
     CDS             complement(13067..13825)
                     /locus_tag="ACL3F5_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0515265.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGACLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(13887..14075)
                     /locus_tag="ACL3F5_001490"
     CDS             complement(13887..14075)
                     /locus_tag="ACL3F5_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0515266.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(14396..14962)
                     /locus_tag="ACL3F5_001491"
     CDS             complement(14396..14962)
                     /locus_tag="ACL3F5_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515267.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(15230..16910)
                     /locus_tag="ACL3F5_001492"
                     /pseudo
     CDS             complement(15230..16910)
                     /locus_tag="ACL3F5_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(17002..17163)
                     /locus_tag="ACL3F5_001493"
     CDS             complement(17002..17163)
                     /locus_tag="ACL3F5_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515268.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(17847..18575)
                     /locus_tag="ACL3F5_001494"
     CDS             complement(17847..18575)
                     /locus_tag="ACL3F5_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR0515269.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKNRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            complement(18702..19229)
                     /locus_tag="ACL3F5_001495"
     CDS             complement(18702..19229)
                     /locus_tag="ACL3F5_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGR0515270.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(19415..19588)
                     /locus_tag="ACL3F5_001496"
     CDS             complement(19415..19588)
                     /locus_tag="ACL3F5_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515271.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(19662..>20004)
                     /locus_tag="ACL3F5_001497"
     CDS             complement(19662..>20004)
                     /locus_tag="ACL3F5_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HGR0515272.1"
                     /translation="VVSGKLKKLLSDKEKLSPKKWNEEKILLMSNLEEINKEKDKIKD
                     EYQEINHIKYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYRE
                     MMKNKKMDQER"
BASE COUNT         5835 a         3905 c         2729 g         7535 t
ORIGIN      
        1 ttaatttttg ttgggaaaat gggaaattat gaaatcaaaa cttggcatca cacttagaaa
       61 agttcgtaaa ggaaaacaaa ttagtctatg ctctgtagca gatgaacatc tttcaaaatc
      121 acaaatatct cgttttgaac gtggggagtc agagatatct tgtattcgac taatcaatat
      181 tttagacaaa ttacatatta ctttggatga gttccttgtt ttatacaatg acgactatac
      241 cagttccgaa tcatttgcta atctagtaca gtacattcgt aagcaatatt catcacaaag
      301 tatcaataat atagcatgtc tactttctga tacttctgat tacactctaa attcttttga
      361 gaaaacaatg gtaaaatcta ttttacacac aatggattcg aacatcattc catcagatga
      421 agagcttctt catctgacag actatctttt caaagttgaa aaatggggct attatgaaat
      481 cattttatta ggtaactgtg tacgcacaat taactacaac tcctacttct tattaactaa
      541 agagatgtta aataactata tttactcatc tctgaataaa actaataagc agattgtctc
      601 tcagcttgct attaattgct tcattctaag cattgataag gaagaatttt ctaattgctc
      661 ctatttaatt agtaagataa agacattgtt ggacaatgaa ctaaactttt atgaacaaac
      721 agtttttctc tatgcaactg gttactttga atttaaacgt tgccaatcaa ccagtggaat
      781 tgaaaaaatg aaacaagcca tacaagtctt cgatatttta ggagaagata agttaaaatt
      841 acactatact gaccatttta ataaactagt aaataaaaaa taaatgaaat tattctctat
      901 cttttaacta attagtcgta aataatatta ttctagtaag gcattctcgt gaaattttag
      961 aactgtaaat ttattggtat taataatttt cacaaacaaa tccaatcttc tagctatctc
     1021 ctcatattta ttaatttcat taccaagttc ctgttgtaat tttaaaatat ccgtattgag
     1081 tcgatctaac attattgatt ccgtcatgtt catttggtca aaatcatact tagctaattt
     1141 tctagtctca tgatcttcac tcttcaaatt gataaggact tccgccatct tgtttaaggt
     1201 ggcgattttt tcttgggttt cttctagctg catatcaatc tctgcaattt ctaatacaag
     1261 ctcatctttg atttcttggt attgtttgtt cgtgttagat agttcaatca taagattaat
     1321 ttcagaaatc ttctctttaa gactttttaa agttggtcgt ctatatggga gttttttgct
     1381 atcgttgctc aattgtctga ttaaggtcct acccttgatg aaacaattat tatccctgtt
     1441 ttctttatta taaacaaagt aagaagacgt ttctcgaatg tagactttat attttttatg
     1501 attttattct tccataatat ccaattgata gttgggaatg aaaataagac cgctctgttt
     1561 gacaccgaaa gacaccttga tatagacgcc cttatcaact agcttctcta tttggttctc
     1621 tgcaagttcc acttcaaatt cacgaacagc atctctcttt ttcttaaatg tctcaaaggc
     1681 ttcctcgatt tcttcagcgg agactttctc cttatgctgc tcctctcgaa aagtctgaaa
     1741 atcttcctga agattttcta atgcttgaat atctctaact tctctatctt caaaataacg
     1801 attaaaaaat tgaacatcgt acaatttctt ctcacttatt tttttatgac tcaggcttat
     1861 ctttttgcca tcttcttcta gggtaaacat cacatttttc tgttttaact cgatggttag
     1921 attcaactct ttagctttta catgcaattc ttctaatgaa taaacagact ttagtaaaaa
     1981 ttttaaacga ctttcaatct cttgtttggc aaaatatgtt ttaaaaaagt cttcatcata
     2041 taaatctcgt ttactaagtt ggcgacctcg aattggtttt atcatcgttc tatctgtcat
     2101 caaaaaacgg ctatgctttt gactaaaatc aatctgaaca tgcaactgct ttgctttctc
     2161 taaaaaatca tcaaacgatt tagattgctg tagcaaaaaa taaagacgtt gtttcaattc
     2221 aaatttataa ctagactgcc tatattttta atagtcacgg taggaataac gcttcccgat
     2281 aatttttgcc cctgccattt tagaaatacg atctgaaatc atacgtaaat ttcgttctaa
     2341 ggcataattc catatcaatt ttttatctga attactgtct atggcattga ttaggatgta
     2401 gttgtgaaca tgatctttgt ctgtatgagt tgctacgata aacttaaagc gacctccagt
     2461 caattccatc atggtctcat aaccaatgcg gttaatttct tcaggtgtca gattatcttc
     2521 aggagaaaat gattggatga gatgatgggc atgaatagtt tgttggtgtt tttcttgtcg
     2581 gtcatttctg gactcgtaca acttgtcgtt attagtaaag ttaacattgt acatttctac
     2641 catttctgca tggctaggaa aatctaagta attactcatg ccaaaatcag atactaattt
     2701 tagattatct gttttatctg gattgaggat atatttaatc aaacgcctac gatatttttt
     2761 tccgtgcgtc gcaaagtgtt tagtaactac catgaaactc cttcagtctt ttcacctcca
     2821 cttgaaattc tttgtccact tccttaatta actctccgac tcctttactc aattcttgta
     2881 attggtcctg agaaatcaga tggctttgat tgatcgcacg cgcaatttga ttgatgttat
     2941 ttccaatacg tctcaattca aaaactaact ggtcataagt atccgtgtta atcgtgacaa
     3001 atgacatatt gggattaagc aaaacttttc tggcatagac tgaaaaattt tgacaattgc
     3061 tcttagcaat ccgttcattc aattggtgta attctgaatc tgttagaaat acttttttga
     3121 gattggtacg ataacgataa accatagtag cctcctatct catgtatttt tcacgaaacc
     3181 cacgactgag tgactgtact tgattgactt ccgcaatcaa ttcttgaacg caggtcaata
     3241 agattgacac gtgttcttga gtcacttggt gattctctct tgcgataatc aaaaccaaat
     3301 gcacatctcg actgatctgt tcaaactttt gagactgcca aagggaaaac cattctttgg
     3361 cagctaactg tttgtcatca atcatcaaaa ttttatccct gacgaatggt gaaaagtgac
     3421 gataattatc aacctccatc attttttcaa tctgttttag ctcatctgcg gttagattta
     3481 cctcttttcg aatgtcacgg tactgttcag acatctcttt tcctcacttt catcctttct
     3541 cgggtaaacc ccgaccccgt gtgtcatacg ggaaatttct taaagtcctt gttcggtctt
     3601 tgcgagctca ggcattgtgg ccacaatacc caaaaaatca tatcgccagc taaccaaaac
     3661 cttccagttt tgacagccaa cgataagata acttggtggc ttcgccccca aacccccagg
     3721 taaaattctt agttggattt ttaaaagttg agaaaagtat agcagaagaa atttggggaa
     3781 gttatcacaa atcaaatagg gactaatctc taacaccact gcatgtaccg tcctatattt
     3841 atgatcagct cccatcgtca ctgtcttttc ataccaggaa ttagaattga caaatttaat
     3901 tagagaggta ttcatttaat tgttcacttc ttcgctccat ttccattaca gaaatttctt
     3961 caatactatg tgttcagctg actcccatga ttcgttgtac tacgtcctaa acgctcacgg
     4021 aataagccgt acatctttcc tagtttactc tcgtaattta cgtatatagg ttacgacacc
     4081 tatttggatt ttagagttcc tcatccgcta tatatggctt caagtcacga ttctgtttgt
     4141 agaaccttga tttcgctaat tccttcctat cccccctacc tcacgatatt caggcttagg
     4201 agtcgctatt ggtttcatct gcagcaaaca tccacagagg acttggacct cagatgtaca
     4261 ctatgcctgt cggacaaaga aaaaagtagg ctaaatttct aacctacttt ttctgactct
     4321 actctgataa agccgtctca tatatagaca ttttatgctt gaaggaatct tttcctccct
     4381 ctaattgatt gatgatatga ttttttatat atttttcact aacatatccc tgtgattcaa
     4441 tccatccgtt aactccatct gactccataa taacaacttg atctgtcata gaatttgtta
     4501 caattgtagc attatgtgtt gctaaaataa tttgacgttg agctttcaca tctctaaact
     4561 gctgaactaa atgcctgtaa atataacgat tgtctagatt gtcttcaggc tgatcaataa
     4621 tcaatggtct gaagtcttta gaataatcac tatatgctaa taaaaaatca agcatggcta
     4681 caactttttg tcccaaactt aatacaccaa cttctttata gagaatatca agttgttgcg
     4741 aagattcttt cgagttaata ttaaactcca aaaataacct ttcattagct acatgctctt
     4801 ttaaaactct tttaaactca tttaataaac tactattttc aattaaagag tagatactct
     4861 tttttaaatg cgtaatgttg tattcattaa tttcagattt atctctccaa ttattttctt
     4921 gttttgcaaa attatcttca gagatacttt ttaaaagcat aaaatactta ttagggatat
     4981 tttgtcttac aatgacttta acaaattctt tcattcctaa ttcccgatag ataagatata
     5041 aaacgtctgc tacatcttgc atactaattc tataattatc aaacgaagaa cgattattct
     5101 tgaaaagata attttcgaaa tgcggttctt cccatctatc aatttgttca taacaaattc
     5161 ttaacttacc aatctgagtt tcattaaaat cctcaataat tttgagtatt aattgcttct
     5221 gctgttttaa atattcatca agttccttca attttacttc aaacgatttg agtgtctgag
     5281 ttcttagccc atagtctggt ctcggtaatt ttttattttt aatcattaaa ttagaaataa
     5341 attctgtaat tttttcaccg tcagctgttt taactaactc attaacagaa tatctcctat
     5401 caaacatttt ctctaaaatt ctagttttat caactaattt aaaatggtta ccttcaactt
     5461 tataaactgt tgtgtactga gaccgtgtcc attctttaat agtgtcagaa ttaaatctat
     5521 aaggatagcc aaacttattc tctcgatttt gcccataata ttgtaaaata ttatccttat
     5581 tttcttgttt gacatctggt aaactgactt caataatata ttcagtttct tctaaaacat
     5641 agagtacaaa agcatttgca tggttacata gaaattccaa tttgctttgc ttatcacaat
     5701 cttgagaaag tacaaattgt aacatatcaa ttaatgtgct tttccctgta cctctccctc
     5761 caattaaaca attcatagat ggtgaaaatg ttaaaaagaa gtctttatct ttttttaatt
     5821 tatcacctgc aagaaagctt ctattttccc cacgattttc tatatataat ccttttatat
     5881 aagacttttg tttaaagctt ggcttacata aactaactga tacgttataa tcaaacaatg
     5941 cttcttgaaa catcttgaaa gaaatttttc cacctttcaa ccacagattg ttcttcccga
     6001 gtgaatcaat ttcgtgagaa tcattatcta atagaaagtt gggctcacaa ttaaaatctg
     6061 ctaatagttt ttttctagaa ccttcaatag aatttatatt tttaactcca ataaatcgtg
     6121 tattttcttt agaaaaaatt tttcgtttat atgcacctga taagtgagaa ccttttttca
     6181 aaatgtcata actattgaaa tgagcaatat agttaactat tttttgatta ttgaaatcct
     6241 tcattatagt cagtgaatgt tgataacttc catctttctc acttataata ttttcactta
     6301 accattgatt aacccatgat tcttgttcat aatcatatat acatacaata tgcaatttat
     6361 ctgctgcact aatttctact ccatgtaaaa tatgaggatg tatatcataa atcggataat
     6421 ttttcattat gattgagact gccatttgta actttttaat acctttggta gtattatgat
     6481 cagttactac aactatttct attccatttt ttatgattgc ctctgctaac ataagaaaac
     6541 taatatattc ttttgaacta gaaaaaacaa ccttatcaaa attactaaaa aaaattgtct
     6601 tatcaacttt tattttctta ttttcaaaaa atatatcata tagttcatct tcagtaattt
     6661 ttctatattt cgttgcagtc caattagaaa atagcttgta atcataagaa acaggtgtat
     6721 gcaaatgaat taaagtcttg tgaaagctac cgaatttctc tttggaattt gttagttctt
     6781 gataaacaga ctttatcttg ttattaaacc ctctcatttc tattctccta aaaatatcaa
     6841 ttgtttattt ttcaagtaat tcattaagtc tcttttcccc cacctgcaac atctcctttt
     6901 ctacctgact ccactctcca aacaataact catgaagaac atctgctgct gaagttgtat
     6961 tttcttttga atcatataca caacttctat ctcgttggta aatttgaatt ctttcaaaaa
     7021 tagctagttc ttccaattgt cgtgtattat caactagatg atttacaatg aaatcatgat
     7081 gttcttttgg agttgcgcgt gcttgatttg gattgataat gtacagttct tcataacgga
     7141 taagagtact tagatacgac aattcaggct ttgtcgcaat taaggccaat tgtacttcat
     7201 atcccttatt tttcaagagt tgtgctgttt tctttggaac gtcaatcgtt cgtaaagttc
     7261 cctctatcaa aagattgtat cccaaatgac tcaattcggt tactaaagac tctaccattt
     7321 ttcctgcaaa atctttggtg tattctacac tgtctttgcc atattcttgc tgcagttcta
     7381 aatagtgtgg atgctgagaa cgaaaactat caccatctat gataacaata tttccttgaa
     7441 attctttctg tttaatacga tgaattgtag tcttaccggc accactttga cctccaagca
     7501 aaatcgctat aggttgttta ctggactttt ttcctcttgt cagtgaacga agattccttg
     7561 ctaaagcatg tttgaattca ctatcagtat aatcttggat ttccattaag ctaccatccg
     7621 cttttcagat atctctaaca tgcgctcaat tccatccaaa tagccgctat atctctctat
     7681 ttcatcaaaa ttttctacta aatagatatt tgtctgaatc aagtcagata gatcatcact
     7741 cattaaaatc caaggattag attcatcatc aatgctaatt ccctgactat cttgataacg
     7801 atagagtcga gataatagat tagcacctct ttctttcaca atttcaattt tcaaagtcaa
     7861 ttcataatct tcaacaggat tgagcatttt atcttctcct acgatatcga cataagatac
     7921 attaaacttc tgacaaatga tgtctattaa ttcggtagag actgaactcg ttccattttc
     7981 ataacgactc agactatttc gtgaaatacc tacaatcctt gcaaattcgg gttgtgttaa
     8041 gtcatatgtt ttacgtaaga attttatgtt ctttccaatc atagcaaact cctttatttt
     8101 tataaatcca ttatagcata aaaaagcata acgcaccaaa aatggtgcgt tatttcttgt
     8161 ttttctatcc taaactttac ttctataaaa gtcacctaaa gagccataaa tatttattct
     8221 tgtattaatt ttttcgatgc gcaaacgata tctacaaata catctataac gattcacctt
     8281 ttaggatttt tattgtcaaa attgccttta tctacaaaga caaaatgctt ataaaatagc
     8341 ttgaaatcaa ggattatcac ctttttcgtt gtagcaacac tccacatgtg attattaggc
     8401 tattagcaaa gcgtatccaa tacctcaata aagtgttgtt tttactgata ttttaactat
     8461 attgtatagt ctactattta aatctcaatt aggatatttt atagaatacc caaaattcaa
     8521 caataactaa aagtaagatt ccattgtatt tccttgttgg tctttcatat cacgaatttt
     8581 atttttcaga atattaaagt tacaaatttc atctctaata tcgttatccg ctctgtagcc
     8641 attaatcatc tcagtcagag ttttcccttt actaccattc tttatagtag tatttactct
     8701 ttttatactg ctttcaaaag gctcatatgt tttatactta attacttcgt ctttaaaatt
     8761 aaataaaggt gtatccggct tagcattcca taaaataatc aaccacatta tagcattata
     8821 aagctgcttt gcagtttcat tccacttttc aggttgtaaa tttccactcc ctgtattgtc
     8881 atattcttgt ctattattta catgagaatc acctacaagc ggattaaaaa gaggtagccc
     8941 tttgtgatta attagttcta aaaaatccct tgccgcaccc atgcaacact gaataacttc
     9001 cttcttgcca tcaattttac tctcagcgat aaatacataa tattcatctt caatagttgc
     9061 tcctgcatca ctatgttttt gttgatttgc taacagctta atatgtgctt taggctaaac
     9121 ttcaaaatct ctaacaattc tttgtcttgt ttcatgtcct ctacaattca tttaagttct
     9181 cctttacaag tttagtaact agccttatta tactatataa gatatgaaat gtaccataat
     9241 cttcatcaac tagtttttag aaaatcacaa atccatctgg agagatgaca agctgattct
     9301 ccaattcttg gcaattgctt gctagtgcta ctgcttcttt ctctaaaaga taatcttctg
     9361 ttgattggtt gaatattgct ttgaggatcc gtccttcgta tttccattcc agagctacta
     9421 gatcagattt gatttcttga aggctatact tgccatgcga aatgattact gacgcgtatt
     9481 tccgaatctt aatcagcctc ttcataaagt tcagcatatc attgtcactt gatacacgtt
     9541 cccaaggcat acaacgacga caatctggat ctggtcctcc agtcaaggct agctcggttc
     9601 cgtaataaat gcacggtgtt cctttttgta aaaagagaaa ggctaaggct gatttaacca
     9661 gttgaacatc ttcattggcc gtccacagga ttcgctctgt atcatgtgaa tccaagagat
     9721 taaacatgac ctctgaaatc tgctgcttgt aatacataga ctctcaattg atttcatcga
     9781 tgaactggtc tgtcttctta attcctcgta agaaatagtc cttgatacta ttagataaag
     9841 gataattcat gacggcatgg aactcatctc catttagcca aggctgagat gtatgccaga
     9901 cttctcctag gatataaaga tcaggatttt tagctaaaac tgccttacga aaatccttcc
     9961 agaactgatg gtcaatctca ttagccacat ccaaacgcca agcatcgata ttaaactctt
    10021 caatccaata agtcgcaacc tttaaaagat aattcttgac ctctggattg gctgtattta
    10081 gcttaggcat atagtcctcg aaaccaaaaa catgataggg taagtctctc ttattaacta
    10141 gcttttcagt tgtcactggg aattgttgaa tatggaacca atccttataa gcagactgtt
    10201 caccattttt gacgacattt ttccattgaa gagattgcga accaatatga ttaaataccg
    10261 catccagcat gactttcatg ccacgatgat gcgcttgatc caccagttcc cgaaaggtct
    10321 ccttgtctcc aaaatgacgg tcaatttcaa agtaatctgt cgtattgtac ttgtgattgc
    10381 ttgtagattc aaagatggga caaagatata gtccagtaat acccaagtct tgcaagtaat
    10441 ccatatgatc aataatcccc tgtaaatcac caccaaagaa atcatcgctc ttaggtgtga
    10501 cagatgaatc ccagtctaaa gtcccttctg ggtttaatag agcattgcca ttggcaaatc
    10561 tttcaggaaa tatctgatac cataccgtat ttgaaaccca gtcaggaacc ttgcaggcat
    10621 caatctcatg aagataaggc aacttaaatc cattcccaat tgcatgaaga ttttctagag
    10681 aattttccac acacccttta tcgccataca aaatattttg accttctgta tctctgagct
    10741 caaagagata ctggatacgt gcaaagtcaa ctgacacttc aacctgccaa tggtcaaata
    10801 aggtaccaga agttatcttg accatttctt ttgtatcctg ataaaactcc tccataaaga
    10861 taaaagggtc cccatagtgc aagttgatgc tttcaatgtc ccctttctta gttcgaattc
    10921 gaatatggag tttcttatcc ttataaagat aggcatactc cgactcaggc ctatggtaaa
    10981 tagcactcaa ttccatcaat ttgtctccta aagtattcat tcaaatttta cgcaaacgtt
    11041 ttcaaactca atgaatccag tatactattt ttgtaaacta tttgcaagga atgtccgttg
    11101 ttaaaggaac tatcttttaa agtatacaaa aagccttaaa aaaggctttc tctatatact
    11161 aatcctcttt cggttttgaa aatacttcta ctcgctgagc taggactttg atttctacag
    11221 gtaggttatc tgatttatct ccgtcaacat ctgactccaa ttcactatct gaagagattt
    11281 taatattacg cgttttgata tactcgatat tatcatttgc gacaacatcc ccttttaata
    11341 aatcaggaat gacggataat ttggagaata tagaggcatc tttcagaatc aaaatgttgg
    11401 catagccgtc cttgttttct tcaaagattt tcttatcagc gaagtaattt gtcaaaagga
    11461 ccaaaacatg gctagcttca ccaacataat ttccattttc tgtctcaacc ttaatgttaa
    11521 agacctgatc tgtcatgaca gacttcatgg tatttacagc ataggttaaa ataccgaatt
    11581 ttgttttgtc ctctatttca acattgtgaa tcgcctcagg cagagaaccg atactaaaga
    11641 tataaccaaa atagttgtca tttgctttac cgatatcaat cttattggtt aaatcaaaat
    11701 ccagttcgtc aattgcgcca tcgatgtctt gattgatttc caaaagtttt gtaatgaggt
    11761 tacccgtacc gcctgggata atccctaact taggaatgta gtctctctca tcaatacctg
    11821 aaatgacttc attgacagtt ccatctccac caaacacaac cactgcatca tactgctcac
    11881 gagaagcttc ttcagcaaaa tgtgttgcat ccagcgcttt ttcggtaatt ttggtttcaa
    11941 catattcaaa gtattctttt gctttattct ccagtttttc tttgtaatcc aaagccttct
    12001 cgccaccaga agtagggttg ataattacca ttgctttttt cattgatttt atccttaatt
    12061 ttaaatagaa atgtttacat ttcgtcgtat gcaagtaaat gtaatcctat tatacaatga
    12121 aaatacataa aagagaaatc tgatgtactg gaaattaata cgcttttatt ctattttccc
    12181 atcgcctaac tacatccttt aagggttcat ccaagtaaga ataggcctta tccttgatcc
    12241 aatcaggaat accgtaagct gcctctgcta tgctacaagt gattgctgcg agagtatcac
    12301 tgtcgccacc aagtgagatg gcatttctta tcgcatcttc gaagtctcta ctttcaagaa
    12361 aggcgataat ggcttgaggg acagtttcct gacatgtttc gttaaaacga tagttaggac
    12421 ggatttcatc taaagtttga gatagattgt aatcgtattc tttttctata taatccttaa
    12481 ttcgtctttt acactctgta ggattgtcgt taattgattg ctcgtactct ctacaataac
    12541 caccaaagta aaaacgacat agaaagatag catcagctgt agccatagcg cctttgacac
    12601 cttctggatg attatgagtt acctctgcag aaagactcgt aagtcctcta gatgatggcc
    12661 atataccagt tttcgcataa aaaccacagt ccatgatcca agcacatgga gaaatacgca
    12721 tagctgatcc attcccaaag ctattataag gctcacggtt atcgctgttt agccatgcat
    12781 taaaccgagc accgtaatca gcattcggat acattctgcc atatttcttc atcgcgtcaa
    12841 tgaagtcgtc tttttgtcca ccattcataa ttgcttctgc aacagcacag gtcataaccg
    12901 tgtcatctgt aaaaaagcag tccttccgaa ataaaggaaa gtcctttgtt ttgatattgt
    12961 tccattcgta aacagaatcg acaatatctc caataattgc tccaagcatc agattcctcc
    13021 ttgttcattt tgatgctttt tatattggtt atctaccata tttattttag aaaataacat
    13081 cctgttggat tttaaaaatt tcattttttt caaaataggg ttttaccatt tctttccacc
    13141 tagctctatg aaaattgatt gattttaaag gagataggcc ataatttccc aatgcataac
    13201 catcatttac ttcaacaaca agtgttctgc catcgcgagt aacaccgata tctagtccat
    13261 aagctattgg cgcatctttc caacatgata tcgcttcatc aattacactt gcatcaaatt
    13321 gtgcatgata atcacctgta tagggtcgaa catctaatac gcgaccatct aacacaaaac
    13381 aacgccattc agctatgaat tctacaacct cactaatcca tataggatag tcgaaaggta
    13441 gaccaatacc tattaaatca tgggttccat taacaaccct tccagtaaag acttttgaac
    13501 cagctttagg cttaataaat tttccccaat tatcaggtat attcacaatc tctcctaaaa
    13561 taccagcata aatctttcga ccataaaact ctttaagctc aataggatag tcataaaccg
    13621 gaacgtttaa gcccatcatt tttagtaatg ctctagtctc cattatataa tctacaacta
    13681 tatcttcact tgttaactct tttatttcag aaaaagattg atataaaata acttcttctc
    13741 cttgtaagca ggcacctact tgagcattgt atttattaat tgaaacctca cttggtaatt
    13801 tactttgtct aatataaaca accatttcat cactcctata tcactagtgt tacaccaatt
    13861 tgtaaaaaat aatagcaatt ttgctcttat ttttttgagt aaatagcccc cataatatca
    13921 tcgaaataat caacggtatt taggagtaat tcaataacct gggactttgt tagtcgcatt
    13981 ccccttctat ctctagcatc ttctactaaa ttttcaagtt tctctagatt tttatcatcc
    14041 aagctaatca ttattctatt tttatcggtt gccattttca tcacctcaag ttaattctat
    14101 cacaggtgta acacttgtgt caactggctt ttataataca ttagtttaaa agtggagagg
    14161 atttttaaca cagtaacttt aaatctttgg tattaaaaaa ttttcacaat atttatagaa
    14221 ataaaatctg tctcaaatca gttatcaaat ctagtataaa ttatgagcgg ctactctaat
    14281 actttccctc taaacaagaa aaagacttac actcaagggt tttcttcccc ccttcgttat
    14341 aacgttttga ctcttttact agcaaaggta tatactcaca aggaactttg gttgactatt
    14401 gaatctctcc aacttcttct ttaacatatc cttctacatc ttcaatctct acaaacattg
    14461 ggtctaagtg acacaagaaa tgccaaactt cgatcccttt ttttctgtaa agaatcgctt
    14521 caccgtcttc acttccgaaa aagcttctgt cgatttcata tccgcggctt tctaagaagt
    14581 cttttgcttt acgatagttc gtttctcttg tttcgacata ggctttaact tcatggttgt
    14641 taacgacata tgcatcaatt tttgaatatc cttcgatcac tctatcattt ttgagggata
    14701 aatttgaaat ctctttccaa ataatgttta cattttcctc aggatcgaac ataaatttag
    14761 ataaaggaac aatatttccg ttaaaaataa tttccatata atccggtatg tttttaggat
    14821 taaaatactc cacttcaaaa ccatcttctg tttccagagt gtatcccggg atttgagcta
    14881 caaaggcttt cccatcttct atggaatcaa atgctactaa atctttagaa taatcatttt
    14941 ggtacaattc caatataacc atcgataatc tctccatttt cattatcagg ctaatgtaaa
    15001 taagcacgtc acctgaccaa ttcaggctct ctgtatcatc tcatcatatt tcctacttac
    15061 tttacgagtc ctatacccag aacacacctt atcgaccttc ggtctcacct cgtcgcattg
    15121 gctgaacatc tacttttact tcgctgatgc ttcaactcgt acaagcagtg ataccgcctc
    15181 agcgtgatgc gtcagtggga ctcaaaaagt ttggggaacc ttttgaggat taactacgtt
    15241 tctctaataa acttacacat tcaacttgtt catcattgtc caaatctatg ttgagatttt
    15301 cttctataat tggtagctta aaagtaatgg attttagcca ttgtccgtta gattgttttt
    15361 cttcataaac ttgaatttca gaaatcaaag ctgaaattaa ctgcctacgc tctacatcat
    15421 tcatgacttt atagagctta tcaaaataga tcagaacctt atatatgtta tctcctgtaa
    15481 gcttttcagc ttcaatagtc tgtttctttg ctttcgcatc aattagtgat gattctaatt
    15541 catctatttt gtcatacata cgatatagtc tatcatctaa atcctgtttc cttctcttat
    15601 aatgcttatc ttcaacatct aaattatcta tttcctcaat tagcttaaac tttgtagaat
    15661 gactctttct caattccttt tggtaattat ctatttcttt ttctatttca gaggtatcca
    15721 ccttcatgtt gattttttct tgcatcatag aagcaaattt cggattactt actatcttga
    15781 caatcacctc tgcaacagca tcatctaaca attcttctct aatttgctta ctgaatgtac
    15841 acttatgacc tcttatcatc tgcctatgtt tacaaccata gtaataaaaa tctttatact
    15901 ttgtgccatc tttctttttc ttgatacact tgttcccaaa cattcccact ccacatatcg
    15961 ggcattttac aattccagaa agcaagtgtg tgcgtgtatc ttttccttta ttcacatgct
    16021 catatttctt tgcttgagat tttagcttaa cctgagcagc ttgccaaact tcatcggaaa
    16081 ctatagcttc atgtatccct tcagatatta gatattcatc ttgttcaacc tgcttatatt
    16141 catttcttgt accatgaact ttttctaaag ttcttcttcc aaatgctatt ttcccattat
    16201 atacaggatt ctttaatatc tttcttataa gacctgcatc aaacaaagga ttcttaccat
    16261 tctgtcttgg gatttttcta attccatgat tctctaagta tttagatatc ccattggctc
    16321 ctatcgtagt atttacatac tggtcgaaaa tcgttcttat tgcaactgcc tcttcttcat
    16381 ttataaacag cttgccgtct tcaagtttat atccatacgg agccaaagcc accattccat
    16441 tttccttccc ttgctttttg aatgcgacct tccattgttt gaatacggat gttttctctt
    16501 tctatttcag ccacagctga taaaacagaa atcattagtt tcccagcatc tttagatgaa
    16561 tcaatgccat cttcaacgca gataagatta actccataat cctgcattat ctgaagtgta
    16621 gaaagaacat cagcggcatt tcttgcaaat cttgataact taaacacaag aacaaaagat
    16681 actccatctt ttccagattt tatatcttcc atcattcgat tgaactgtat tctaccttca
    16741 atagacttgc cagacttccc ggcatcttca tactctccaa caatttcata atcgttgtaa
    16801 atagcaaaag ctttcattcg tgatttttgt gcctctaacg aatacccctc tatctgtatt
    16861 gacgtagata ctcgtgtata gaggtatact tttatttttt cttttgacat agtattaacc
    16921 tcaatataat ttttctatat catatataat ttttttaatt taactttgga ctatcatttc
    16981 aagtatatta taacactttt attagtccgt ctcaatttgt gtttttgcca tgtcaaaact
    17041 atttttcatc tcttgatttt ttgctggcgt tggatcgggt agattatcta aatctaaagc
    17101 accagcatat tttgcaatca gatttgctat taaatcagcc aatccattcc agtcattgtc
    17161 caatatatac ctcctctaaa gttttatatc taataattat ttgtttaatt aagttttttg
    17221 acattgacaa gtgctttgga ttagcaacat aggaatctca cctccgcctc tattccggat
    17281 gagccggctt caaccttaga agtatcatta tcctcatttt cttcatagcg gatagggtat
    17341 ccctccctat attcaaactc ttacttatcg ctcactttct ttttgcttag cagaactttt
    17401 tttgtcgaat tattcagccg aaagatcttg acggataggt tattacgctc caaaaataat
    17461 taacgtcttg tcttggtcta ttcaattgtt aaggttcaaa atttatcgag agttattaat
    17521 ctttttaaaa tttgaccatc agaaaatatt tatcttgatg taacaaaatt ctataaatta
    17581 ccctcttata cttaacagtg aaaagaagtc tttcttggta actaattttg aaatagaatt
    17641 tgcttatata aaaaggtcca attcccactg cataagtagc agtgaaaatt agaccctctt
    17701 ggtaactgtc atctaaaagt cttctagcat ttctttaatt ttctaatcgc ctttaaagtg
    17761 tcatatttat atttttttat ctctggcata ctttgatacc tttttagact taaagtcttt
    17821 aatagtgcct ttccacctct ttttatctat aaagattctc ctacatcata attcattttt
    17881 ttatttaaac ctttctgtct tagtttgtct ttatcttctt cataccattt taagattgtc
    17941 acatagtggt tttgataggt cttaccactg ctttccatgt atctggatag tttatttatc
    18001 attatatctg tgtgtgagtt taatttttct tttagatttt tatattcttc tttgcttaac
    18061 cttacatttt tgaattctcc ataaaaaatg ggggtggact ttttatctat ctctccctct
    18121 ctctctttat ctatctctat atctttctct atctctatct cttgtcggac atgggttgga
    18181 ctcattaagg acaatgtcct ctgtttattt tgtctgtatc ttctgttttt ctctgcccag
    18241 gctgtttctg atccgattaa gtttggtatt tcagttaggt agtattcatc attttctgtt
    18301 acaacttcta ataagccttg attgattaaa taatttactg ttaccattac atcatcgtct
    18361 gtttcatcta tggttagtgc taactctttt ataaaatcac tttctactcc gtcataatag
    18421 agtttgccct catcttttag gcttagtagt agaagtttta ggtagattat cgtataggta
    18481 tctcctccag atattctcct taaccttttt atccttttgt ctgtgaaaaa ttcttctttt
    18541 aattttatcc aatagtatct tttgtttgtt gccatatctg ctcctttctt gattttcgat
    18601 aatcgaaatt cttgatttcc gattttcgga attctggact tctgtttttc ggaagtcttg
    18661 ttattatggt tatttaaggg tgtaactttt cgttactccc tttagatttc tctggtcata
    18721 tcttttttgt ttggttttac tttttctttt actttccttt ttcctttttc ttttgtctta
    18781 tctttgtttt tggataggtc tttgtatttc tttatttgtt ttaggatact ttctttttct
    18841 tttttatttt ccttggctat gacttgctta aaggcatatt ccattacttt tatgtctttg
    18901 gcttggaaga atatttcata gtttttgctt tctttgtttt tcattactga gaaacttact
    18961 ccaagtttgt ttagttcttt ttttaagtct ttgaggtcga tttgatctat gcttatattt
    19021 tctagttgtc ctttcttgta gaggtctttt attttcattt catcgcccat aagacttttt
    19081 aagtttccat ttgctttttc taaagtttca ttcatctttt ttcttatttc tttttctaaa
    19141 ttgattgatt cttttgttgc ctttattgtg tatgatatta tggtttgtgc tgcttgacct
    19201 gcttccttgc ttatttcttc gtttatcatg cttttctctc ctttgtttga attaaaaaag
    19261 ggaagtatag gttttaattt ttctatactt ccctttgctt gtttttattt tattgttctt
    19321 ggtggtggaa tactttattt tgatgttttt atatatttct taggtctttg taccttttat
    19381 acttttaaaa atagcttaca ctacctttcc acctttaata gtttatgtgt gttcttttgt
    19441 ctgatagata gtttttcatg ttagaatata taatctgtat ttcttcattg ttcattgctt
    19501 ttatttcttc tgtgctttta taggttttgt atgttccatc ttcatttgct tttatgagtt
    19561 catctattag ctcttgcctt ttattcatct ctattacctc ctagatctga ctttagttgt
    19621 ttggtcatat tatagcttgg ataagatatt tttaccaggt cttatctttc ttgatccatt
    19681 ttcttgtttt tcatcatttc tctgtattca ttatctttat tgacttggtc ttggaacttt
    19741 ttaatctgtg ctattacact tggtttttct ccctgtttta ttagcttatc tatttctatg
    19801 gataaatcta taccaagttc tttgtttaca aaatctactg aatattttat atgattaatt
    19861 tcctggtatt catcttttat cttgtctttt tctttattta tttcttcaag atttgacatt
    19921 aaaagaattt tttcttcatt ccacttttta ggacttagtt tttccttatc tgataggagt
    19981 ttttttaatt tcccacttac tact
//
LOCUS       DBEJJE010000039        18659 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEJJE010000039 DBEJJE010000000
VERSION     DBEJJE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.39"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..995)
                     /gene="lytB"
                     /locus_tag="ACL3F5_001498"
     CDS             complement(<1..995)
                     /gene="lytB"
                     /locus_tag="ACL3F5_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0515273.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGG"
     gene            complement(1037..1975)
                     /locus_tag="ACL3F5_001499"
     CDS             complement(1037..1975)
                     /locus_tag="ACL3F5_001499"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0515274.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1986..2786)
                     /locus_tag="ACL3F5_001500"
     CDS             complement(1986..2786)
                     /locus_tag="ACL3F5_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0515275.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLFEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(3036..3416)
                     /locus_tag="ACL3F5_001501"
     CDS             complement(3036..3416)
                     /locus_tag="ACL3F5_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0515276.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3474..3833)
                     /gene="rplT"
                     /locus_tag="ACL3F5_001502"
     CDS             complement(3474..3833)
                     /gene="rplT"
                     /locus_tag="ACL3F5_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0515277.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3885..4085)
                     /gene="rpmI"
                     /locus_tag="ACL3F5_001503"
     CDS             complement(3885..4085)
                     /gene="rpmI"
                     /locus_tag="ACL3F5_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0515278.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(4118..4648)
                     /gene="infC"
                     /locus_tag="ACL3F5_001504"
     CDS             complement(4118..4648)
                     /gene="infC"
                     /locus_tag="ACL3F5_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0515279.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTMKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4664..4795)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4955..6136)
                     /locus_tag="ACL3F5_001505"
     CDS             complement(4955..6136)
                     /locus_tag="ACL3F5_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515280.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(6140..6727)
                     /locus_tag="ACL3F5_001506"
     CDS             complement(6140..6727)
                     /locus_tag="ACL3F5_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515281.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6759..6947)
                     /locus_tag="ACL3F5_001507"
     CDS             complement(6759..6947)
                     /locus_tag="ACL3F5_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515282.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            complement(7126..9366)
                     /locus_tag="ACL3F5_001508"
     CDS             complement(7126..9366)
                     /locus_tag="ACL3F5_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0515283.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9350..10000)
                     /locus_tag="ACL3F5_001509"
     CDS             complement(9350..10000)
                     /locus_tag="ACL3F5_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0515284.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(10068..10637)
                     /locus_tag="ACL3F5_001510"
     CDS             complement(10068..10637)
                     /locus_tag="ACL3F5_001510"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515285.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     SNKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10814..11925
                     /gene="ald"
                     /locus_tag="ACL3F5_001511"
                     /pseudo
     CDS             10814..11925
                     /gene="ald"
                     /locus_tag="ACL3F5_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12226..12551)
                     /locus_tag="ACL3F5_001512"
                     /pseudo
     CDS             complement(12226..12551)
                     /locus_tag="ACL3F5_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12554..13054)
                     /locus_tag="ACL3F5_001513"
     CDS             complement(12554..13054)
                     /locus_tag="ACL3F5_001513"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515286.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGFDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            complement(13247..14215)
                     /locus_tag="ACL3F5_001514"
     CDS             complement(13247..14215)
                     /locus_tag="ACL3F5_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0515287.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14301..14516)
                     /locus_tag="ACL3F5_001515"
     CDS             complement(14301..14516)
                     /locus_tag="ACL3F5_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0515288.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14525..15379)
                     /gene="cvfB"
                     /locus_tag="ACL3F5_001516"
     CDS             complement(14525..15379)
                     /gene="cvfB"
                     /locus_tag="ACL3F5_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0515289.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15439..15996)
                     /gene="frr"
                     /locus_tag="ACL3F5_001517"
     CDS             complement(15439..15996)
                     /gene="frr"
                     /locus_tag="ACL3F5_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0515290.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(16005..16742)
                     /gene="pyrH"
                     /locus_tag="ACL3F5_001518"
     CDS             complement(16005..16742)
                     /gene="pyrH"
                     /locus_tag="ACL3F5_001518"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0515291.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16826..18160)
                     /gene="trmFO"
                     /locus_tag="ACL3F5_001519"
     CDS             complement(16826..18160)
                     /gene="trmFO"
                     /locus_tag="ACL3F5_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0515292.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALINAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18405..>18659)
                     /locus_tag="ACL3F5_001520"
     CDS             complement(18405..>18659)
                     /locus_tag="ACL3F5_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515293.1"
                     /translation="IHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         5363 a         4250 c         3437 g         5609 t
ORIGIN      
        1 ccaccggatt tgaagtagta ccaagcttga ctatgagaat cgtagaccca ttctttttca
       61 gctattttcc catcagattt gaggtaaaac caagattcct tatcccaaat ccattcattg
      121 gctgtcatgt aaccaccgga tttgaagtag taccaggctt gactatgaga atcgtagacc
      181 cattcttttt cagctatttt cccatcaaat ttgagataaa accaagattc cttatcccaa
      241 atccattcat tggctgccat gtagccaccg gattttagat aataatagtg accattctcg
      301 aaaatccatt ctttatcagc atagtttcca ttttctttga tgtaaaacca agattggtat
      361 tgtttgtcaa aaagccaacc ttgctgtact ttggcaccac tagcattcac ataagcttga
      421 ttaatccact gacttgtcag tagataacca ccggatttga aataatagtc cttcccttta
      481 atttggagcc attctttctc tgcgtgctgt ccatctgctt tgatataaaa ccaagcatcg
      541 tattgagaat catagaccca gtcttctatt actttggcac ctgttgcacc aacataggaa
      601 gttcctaccc aagcatttcg tttcatcttt ccatcttggt caagataata aaaggctccc
      661 ttgtcttcta cccattctga tttggccata tagccaccag atttgaggta aaaatagtcg
      721 tcaccttgct ttagccattc attttcagca tagttagcat ctgcttttat atagaaccaa
      781 gattgataat gagtatcaaa aacccactca ttcgctgctt gactgccatc ttctttcaga
      841 tactgttttc cttgccaagt accatcacta gccattgcac cctctggact agctaagaaa
      901 aatagcagag ctaaaaaaat aaatcttact ttcttcatta accttcttcc tctgttctta
      961 tttattttat tgtaccaaaa ttctcctaaa ttcatattac aaactaataa aaaatcaaga
     1021 acagattgat tgcagtttac ctcagagact cttttacttc ctgacggagt tcttccagac
     1081 tgctaatacc gtatttatcc atgacttttg gtaaattttc gatgatgtca ggacaggcat
     1141 aaggattggt aaagttagct gttccaactc cgatagcaga tgccccagcc agatacattt
     1201 ctagggcagc ttcagccgaa tccactcccc ccattccaat gataggcagg tctgttgttt
     1261 gggctacttg gcggatgagt ttgagggcta ctggaaagac tgctggacct gacattccac
     1321 ctgttccatt ggccaagatt ggttttctgg ttttgaggtc aaagcgcatt ccaaccagag
     1381 tattgatcat ggtcaagcca cttgctcccg catcttctgc agcttttgcg acagtaacga
     1441 tatcggtcac actcggggtt aatttgacat aaactggcac ttctgaggct tccacagctg
     1501 ctttcaccac atcataagcc aaatctggat cttgaccaat caaaagtcca tgattacagt
     1561 ggtcaacatt gggacaagaa atattgagct cgatagcttt tacattagtt gccttggaaa
     1621 tcccatgaga aacagctgca tactcttgtt ttgaaaaacc agctacattg gcaataatag
     1681 gaagatttgg atattctctt tccagccaag gtagcttttc agccaaaaca acctctaaac
     1741 caggattttg caagccaatt gcattgagca taccagcagg cgtctctgcc actcttggag
     1801 ttggattccc aaaacgtggt tcaagggttg tcgccttgat cataatagaa cctaaaaggt
     1861 ctaaatcata gtacttggca tactcttgtc caaagccaaa acagcctgat gctggaataa
     1921 tcggattttt caaatccaaa ccaggtagag acacttgtaa tcgatttgta gtcataattt
     1981 tctccttata atacaactgt tcctgtgcgg aaaacaggac catcttcaca gacgcgttgg
     2041 ctgaccgtct cgctttctgg tacttttaga acacaggcat agcaagctcc catcccacaa
     2101 gccatacgag attccagaga taaataggct cttgggtgat catcaaaggt ttgattgata
     2161 tacttcatca ttcctggagc cccacacgag taaacagcat caaactgact atctaaatca
     2221 ttgataacaa cggaaacatt tcctttgatg ccataagaac catcatctgt cgttacaaag
     2281 acctgaccat actgagccaa ttccgttttc aaaataacag catccttatt agcaaaaccg
     2341 aggactgtca ctactttcac tccacgttca tgcaattcct tggccacctc aaacaagggt
     2401 ggaacaccaa tcccaccacc aacaaggaga acctgattct gctcatcaag gtcagacaag
     2461 tcaaaaccat ttccctgagg ccccatcaca tcaagagtgt ctccctgact taaggttgaa
     2521 aaaattgcag tcccagctcc ctcaatccga taaatgaggt gacactgctt gtttgccttg
     2581 tcaatagacg aaattgaaat aggacgacgt aagagatggg catcgtccgg tacacgcaga
     2641 tgaagaaatt ggcctgctcg catggcttca accatttctc cttctaggac taattcaaag
     2701 attgctggcg cgatttcctc ttgtgcaacc accttcatgg tttccaaccg aatgacaccc
     2761 aaacgcttct tacatgtggg attcataact tttcctcctt aaattttaag gggaccagat
     2821 aaagaaaaga ccttgctagt gcaaggcctc agttaaaatc gtacaacaca agagagcaca
     2881 ctcaaaaagt ctcctctaga aaattgcact attcttttat ctgacacctt gtgagtctct
     2941 ctggactccc cttaaaggtt gaatttttat tagtatactc tttcagctaa aaaaagtcaa
     3001 gtagaaaacg aatattctac ttaacttgca cgaaattatt tttcacgaat gacttcgacc
     3061 ttatatccat cagggtcttt gacaaagtaa tagtttggtg tagttcctgg tagaccattt
     3121 ggctcagtca cttcatagcc ttttgcactg tgttcttgat gaagtgcctc aagatcaggt
     3181 gtactgaggg cgatatgggc aaacccatca ccaaccacat acggaccgtg atcgtagtta
     3241 taagtcaact ccaactcata gtcatcaccc tcaagaccta gatagacaat cgtgaaggca
     3301 tggtctggaa aatctctgcg acgcaattct ttaaaaccaa aagcatcttg ataaaatgcg
     3361 attgattttt caagattttc tactcgtaag caagtgtgta gcatttttga agccatatct
     3421 ttctccttta tttttaaaaa gactggacaa tcctgttcca gtctcatcag ttgttattta
     3481 ccaagttttg ctttagctgc atctgcaaga gctgtgaaag ctactgcatc gttaacagcc
     3541 aagtcagcaa gcattttacg gttaacttca atctcagcca atttcaaacc atgcatcaat
     3601 tgtgagtatg aaagtccgtt catacgagct gccgcattga tacgagtaat ccacaatttg
     3661 cggaagtcac gttttttctg acgacggtca cggtatgcat agtagtaaga gttcattact
     3721 tgttcttttg cagtacggaa caagatgtgt ttagctccat agtaaccttt tgctaattta
     3781 agaatacgtt tacgacgttt gcgtgataca acgccacctt taacacgtgc catgttttat
     3841 ttcctccaaa tatttcctag aattgtttac ttacagtcaa gctattattt caagcgagta
     3901 agcattgctt tgatacgttt gtaatctcct gaatgcacca tagatgcttt acgaagatga
     3961 cgacgttgtt tcttagtttt tccgtggaaa cggtgagaag tgtaagcacg gaaacgttta
     4021 agtccaccag aacctgtacg tttgaaacgt ttagctgatg cgcggtgtgt tttttgtttt
     4081 ggcatgattt tttctccttt atttaacttt ctgacaatta ttttttgtca gtcgctggcg
     4141 ccaattgcat gaacatttga cgtccatcca ttttagcacg ttgttcgatg atggcaatat
     4201 cttgagttgc ttcagcaaac tcggctaaaa cttttgcacc aatctcttta tgggtaatca
     4261 tacgaccctt aaagcgaata gataccttaa ctttatttcc tttttcaagg aacttacgtg
     4321 cattacgaag ttttgtatca aagtcaccct tgtcaattgt tggacttaga cgaacttctt
     4381 tcatagtaac aacgctttgt tttttacgtt gttctttttg cttcttctgg tactcaaatt
     4441 tgaacttacc gtagtccata atttttgcaa caggcggttt ggcttggggt tgaatcaata
     4501 ctaggtcaac attagcgtta tcagccaaag cttgcgcttc actgagtggc ttgatgccta
     4561 gctgttctcc ctcaagacca atcaagcgaa cttcacgtac acgaatctca tcattgatga
     4621 ataagtcttg ctttgctatg gttttcacct cttttgtttt attagagaaa aacaatagcg
     4681 gactcgtaaa tatacaagcc cgcacgttat gatagcgttt cttcgaaact tttcatccgt
     4741 agggccaggc aacttaatgt cacaaggcga gaagctctca cttctgcttt tctcaacttt
     4801 tatatgatac caagttttct agctcttgtc aagataaaaa gttatttttt gaaaagtttg
     4861 tgtttgtatt ttggtttggt tttcgaatca aaaagagaga accaagttga ttctctccct
     4921 atgttagttt ttctttagct tccctatagg aaaactaaac tttaaaaact tcctttttac
     4981 gtgaacttcc ccatctttcg ataaatagaa tccccactaa caaaaggata atcaggcaag
     5041 gaagtaagac catccccatg ctccaattta gatcgacatt atcaatctgc ttagataatc
     5101 ttccagataa aatctccact gaacgcaagt aagtaaaggg aatcagatgt gcaatccttt
     5161 gaagaggctg aattgtttgg atgccaaaca ataagccaac aatcccaatg agtgaaagaa
     5221 agaggacagg cattttttgc ttgaaaaagt aagcaatcaa gtacacaact tccacaatga
     5281 cgataaaggc taagaaagct aagagcaagc caggaaataa tacatcttgt attttcccaa
     5341 tagttacttc ttgattcact aagctataaa ttgggtaggg ataatctaac tgtccaaaac
     5401 cacttatcag acttcccact agaaaagaaa agccacagat tccgataaac agcacagtta
     5461 catatcccac tccaactcca agagaggata ttgcaaatgt cacttttgaa acaggatata
     5521 agtgagctgt gtccagatga ttttgatatc tttctgcaaa tagttgtgtt agcataaaaa
     5581 taatcgcaac cacaaacaag cttgggatga taacctctaa aatccagaca atctgatcaa
     5641 tcccgtgggt cggaaactcc aaagtatgtg cttttatgtt caagggatac agggcttggt
     5701 aaatcttccg ttcgcggtca acccccattt ttaagccaga gctagcagtc gggtcatttg
     5761 atacaaattc ataattcttc tcttcatctt gccactgcag atagtaggct tctttccagc
     5821 gcccttcttt tagtaaagtt agaatttctg tctttcgcgt caaaagattt ttttgcacgt
     5881 ctaaattatt tttagcaaac tggtattcct ccgagctggt atcagacatt tgggagagtt
     5941 tctcttcatt ttcattgata gccctctcgt tggctgcaat gcgactttcc aacctgctct
     6001 ccaagctgtg tgagtttgca gtctgactat ttaaataaaa ggtaacaccg agtacagatg
     6061 caaataaaag taagataatc cagtttaaac gacttttgaa aacttttttc aataaaaata
     6121 gactaacatc tttcataaac taaacctctt ctatctgccc ctgatgaatg gttactactc
     6181 tatcgcagat atcaaccaac tcttccttat agtgggaact taaaagaacc agctgttctt
     6241 gtctatcgat ttgtgctagc ctatcaaaaa acttctgtcg ataatactcg tctaagccat
     6301 ttgtaatctc atccatgagc cagcatttgg cctgactgag aaaatacata gcaatcacca
     6361 agcgttgctt catccctaag gaatacttgc ggatgggaag actgatatag tcagccattt
     6421 cccagtaggc gatttcatct ctcaagttta ggtctgactt ccagatgttt tttatgagac
     6481 gaaggtagtc catcccactt aagtttccat ccagccattc aacgctctca taataaaaca
     6541 aagaaggagg aactgcgatg tgtccactac taaggggaag caacttgctc atagctcgga
     6601 atagtgtcgt ctttcccgag ccattgatag caagaaggcc ataaatccta ccctttttaa
     6661 aggtaaaatc cgcatcttgc aagatgactt gtcgcgtttt taaggtaaca tgagtaagat
     6721 ttaacatatc cagccctcct tttctcactc tttaaggatt aataacctcc agtatagtag
     6781 tttatgacct cataacgagc gtagttccag cctccgccaa ctttatactc agaatagctg
     6841 taataacgag accattccgg aatccaagca tactgatggt cgtgatagtt ggtactatat
     6901 tccaaaaccg tattccaatc atacttgtaa cttttagtgg ctgtcacagc agatacactg
     6961 gactgaagaa gaccaataga ttataaacta actaataaaa caacttttgc tgatttttaa
     7021 tgattttata tcctcaatat tgaatacgtt ttcattatac catttttatc attattatgc
     7081 aacaaatttt tagtttattt cactaatcta caacatttat ccttcctatc gaacactttc
     7141 gattttccaa ctatccaacc ccttaaaacg tatagctcct tgctggtcag ttcgataaac
     7201 tttgctattg ataccttcca gtcgtgtcaa tgtttcctga tgggggagtt tcattcgatt
     7261 gctctttcca actgagataa gagtaagctc tggtttgagt ttttctagaa aggctggact
     7321 tgatgatttt ttattgccat gttggctagc tttcaaaaca tttactttca agtctggata
     7381 gtgcttcagc aagtccttct ctcctttctc ctccaaattt cccgtgaaga gaaattgctt
     7441 atccaagaat ttcccataca gaactagggt gtcatcgtgt cctccatctc ccattttcct
     7501 tggagataga acttctaact gacttccaaa aatgggcaag ttctccccta ctgtcatact
     7561 acgcaccttt gtttgagtcg tctgtagttc tgccacaaat tccttctgtt tcagactgtc
     7621 ttttgatact agaatctccc ctacatggaa agccttggtc acctctgaca aatctccaac
     7681 attctccttg tccgtgttag tcaaaattag ctggtcaatc ttagctactc ctcgactttt
     7741 gagataggga atcaaggttc gctgggcatt gctggtcgtc atcttttctt gccatttttc
     7801 gattttctta taagattctg ccttaccacc tacatctatg agaatggttt tcccagttac
     7861 atcccgtagg aaaatacttt ctccttgccc cacatccagc atggtgattt cattttccag
     7921 tggatgcttg gtcaggagaa agagccctgt aatcaataaa ctcaatactg ttaatccttt
     7981 aatgtttttc ctcaaatcat agaccaaagc caaggaaatt aacaataaaa ttaaaaacca
     8041 tgcattgggt tgtccaaaga ccagaggtct acttgtcacc tgtgacacca agcgaataat
     8101 gccctccaac cattcaaaga taaagttcag ctgaatgact ggatagagaa aggaaaggac
     8161 aaataaaata gacaagagcg gtaagaaggt caagtcaaat agaaaggaaa agacaaaggt
     8221 caaaaggata gaccaaggtt gaaattccgc aaaatagaag gatagaatgg gcaatatgcc
     8281 caaggagatg actagacttt cactagtaac agccttgagc ccctcccctt ctttgctggt
     8341 catggtcagg ataaaagcat aagcgcagga caagactcct cctgctgtca agaaaaagtt
     8401 tggcatgaca ataaagagga caagcaccgt caaggcaaaa ttatccaagc ccttaacccc
     8461 atgttgagcc agtagctttt gcaagagact gcgaataacc gatgctgaaa atccagttag
     8521 tcccgcatag ataagggaaa agggataagt cagccatttc aacttttctt gggtcaagcc
     8581 caatcgcaag agaagtttct taaatccatt catgaaaaaa cctacctgca taccagatag
     8641 ggcaaagagg tggataattc ctagactgga ataaagctca ttcatctcct caaagtcggt
     8701 gtccagatgt cccagcaaga gtcctgtcat gtaattgcgc atagggtctg ggaagtgcat
     8761 cttaatccaa accacagcct ttcgacgtaa actggacagg ttttcaccta tatcccaact
     8821 gccaaccttt tggagtgact ggattctttt aatattgagt gtctggtaaa ttccctgagt
     8881 cttcagatag ccttggtagt caaagccacc aaaatttctc tgcccttctg gctccgaaag
     8941 cttcccttct agtcctatct catgaaggtc agttaaagct tgaaaggctt ctttctcctc
     9001 ctcggactgg agtttataat agacttggaa agcacgacca tcagacttac cacgaaagga
     9061 cagactgtca ccgttgacct taatagtgtc tggtaaaatc cgtacccttt caacagaatc
     9121 caccaaattt tgactcactt gactctgttg ccaagtttga aacagaaacc agaagccaaa
     9181 gactccacaa atcactagaa ctttacctgc tgatttccaa ggaaattgga taaagaggca
     9241 gactagcaga aaaacaaaac ccaacaaagc aaaataggat actgagaaaa tggcgtagta
     9301 aagccataat aacagaaaac tcaggtaaat taggggaata gagaaattct taatccactg
     9361 taacatagtc tttaagtttt tctatggtct tggcaccaat gccagagacc ttcttgagct
     9421 cgtctactga cttgaacttg ccatttgcct cacgatggtc aataatgtcc tgagctcgtt
     9481 tccctcccag tcccttgacc tgcttgagtt cttccagact ggccttgttg agattgacct
     9541 tcttttcctt gcttgttgaa gaagctgtcc ccgaaccagt ctgttgacta actgcttctt
     9601 ctcccttagt aggaacgtaa accagagcct catcactaac tttctgagct agattgagcg
     9661 acttgctgtc tgcttgctct gtcaagccac cagccttctg aacagcatca ttgactcgac
     9721 tacctacagg caagtcataa atccctggcg atttgacagc acctttgaca tctactgtga
     9781 ttagatcttg ttcaactggt tcttccttct cttccttgtt cacttccttt tcggatacca
     9841 aatccttgga aacagctgca acttcaacct gcaaattcgt ttcctttaca ggtgtttgtg
     9901 gagctggctt tagcaggaaa aatccgccta caagcaagcc cagaccagta cagatgacga
     9961 tgattttata ctctttgatt ttctcgataa ttgcttccat attttctcct ctcttagatt
    10021 attcgtaaga ggaagaaaaa acagtcgaaa aatttctttt caactgctta tttatttgca
    10081 aaatagtctt ccttggtcaa gacataatga actcttgtca cgattcggcc tttttcatgc
    10141 tggtccatac aagcatatgg ttctgcatgg gaaaaacgca tgcctgattt ctccatgacc
    10201 tttcctgacg cgggattagc cttatcgtga agggcagtca acttattcat ccctatcttc
    10261 tcaaaagcta gctcaatcac agcacgattg gcttctgtcg ttaatccttg attccaatac
    10321 tttttattgc taatgtagcc aatagctgcc ttcttaagaa cagaatcaat cttgtgcaag
    10381 tcaatggttc caataaactg accattgctt tttagttcta ttccccaacg tcccaaggga
    10441 ttaaccaaat agaactgagc aatgttattc ttggtttctt ccaagctttg attggttgga
    10501 aaagtgtaac gtgtattacc cttgtccgag gcatagtcaa acattgcttc cgcatcatcc
    10561 aaagttacag gtctaagcaa taaacgctcc gtttctatag acggatactg ggcaagtttt
    10621 acaaaaattg attccatact tttccctcca ttagagcttg attttcacta gtctagcata
    10681 aaaaaatttg gatgacaagt ttttcttgat ttttgaagcg gtttcatata caatgaaacc
    10741 gtcacatttt tgatttatga actggaatgt gacaaccaaa acaagaccgt caattgaaag
    10801 gtaggttatc tcaatgttaa tcggaatccc aaaagaaatt aaaaataacg aaaaccgtgt
    10861 cgccctcaca cctgcaggtg ttcatagctt agttagtcgt ggtcatcgtg tccttatcga
    10921 aacaaatgct ggtctcggtt ctggctttac tgatgctgac tatcaaaagc aaggagctga
    10981 gattgtcgct actgctggtg aagcttgggc agcagagttg gttgtgaaag taaaagaacc
    11041 tttaagttct gaatacggtt acttgcgcga cgatcttctt ctcttcacct acttgcacat
    11101 ggccgctgct ccagaattag cagatgctat gttagcagca aaaacaacag gaattgccta
    11161 tgaaactgtt cgtgacaatc aaggacaact accgctcctc gttcctatga gtgaggttgc
    11221 aggtcgtatg gctgtttaaa tcggagctca cttccttact aagcaagctg gtggctctgg
    11281 tgttctacct ggtggtgtac caggtgttcc aaaaggaaaa gtaactatca tcggtgatgg
    11341 tgtcgtcggt acacatgctg cccgcatcgc ccttggtctt ggtgctcaag tgactatttt
    11401 agatattagt gccaagcgtc tctcagttct agaagaagtc tttggaagtc aaattcaaac
    11461 tcttatatct aattcattca acattgaagc aagtgtgaga gatgctgatg tggtgattgg
    11521 agccattctc atccctggtg caaaagcacc ggaattggtg acagatgaga tggtcaaaca
    11581 aatgcgtcca ggctctgtat cgttgacgtt gctgttgacc aaggtggcgt tatcgaaaca
    11641 gctgaccgtg tgacaacgca cgatgaaccc gtctatgaaa aacacggtgt tctccactat
    11701 gccgttgcca atatccctgg tgcggttgct cgcacttcaa ccatcgccct aaccaatgtc
    11761 actcttcctt atatcgaagc tttggctggc aaaggattcg cacaagcaat ctctgaagat
    11821 gaaggcttgc gtcaaggtgt gaccacttat caaggttact taactagcct accagttgct
    11881 caaggactta atcgtgacta cactgatatc aatgatttag tataaatttt gaaaagaaaa
    11941 gggtgacttc gcaagtccta cccactgtgc tttgtgtcat cagctattac atcgttggtt
    12001 tattgtactg tatactttgc aactggagac tttcgttcca gactcaattg tgcataagaa
    12061 actctaaatt gaataaaatc aacagagttt cgcccaacca cttcgtcttg taatgacaat
    12121 tatataaacc aaaggaagct gagctcttta gtcccagctt ctttttatat ataaaatttt
    12181 acccgtgcaa agacagggcc ttagcagact tcttttttac ttcgttcacc cttgcttttt
    12241 ctttttaggt ttgggcgttg gcagttggtt atacatagct aaaatcaggt cttatagaaa
    12301 catcttatta tcaagttctt ccactcaaat catttctttg gcacctttgt atggaaactc
    12361 aaaagaagat tggtcaatct tatctaagac tgcttgcacg ggtttaacta aaagcgatcg
    12421 tcataaatgc cgccaataat cttgccgcgg aagtaaagaa tatactcccc catcatggaa
    12481 cggtaagtca catcatctaa tcctgataat tgttccaaaa caaattccaa atagttctta
    12541 cttgatgcca tttctaatct tctaggctct gttcaacgat aacaaccgta tagagttctt
    12601 gcttaacctc gcatccaatt gatttaaagc cctgcttttc ccaaaaatgc tgagattgcg
    12661 gatttccctt aacataagcc aaacgtgcct ttcgaaagtt cttagcaaaa taagctagtg
    12721 cttctgtcac aatatgacta ccaatccctt tcctctgata ggcttgatca accataaaca
    12781 aaccaataaa aacagtctcc tcatcaggat atgcatagac aaaatccata acagccacaa
    12841 ggtcaaatcc attccaaaat ccaacaaaaa acttatcagc cttagcttta ccttcaggta
    12901 gacaaagcat gtcctctttt acagttgcaa aatttggctc tggtggacaa tgctgaaaat
    12961 acagaggatt actttcatat aaagataaaa tacttggaat atccttttca gttagtatcc
    13021 tacaactgta atacttagat agttggtcaa tcatcttttc aaattcctac tttcttgtgc
    13081 cctgtgatta tgacacagga agatgcactg atcgtcatca gccacataaa agttctttcc
    13141 atcgtgccta atcgttgtct caaacctttg gataaaacct ttagcctata caactggatt
    13201 ttcctctctc aaaagtatat tcttttgcag gcgaacttcc tcaaaatcag tcgtgtgcaa
    13261 cttcagtaga atattcatag gctcggataa tctgagcgac aacaggatgg cgaaccacat
    13321 ccttggctga aaaatgaaca aagtcaatct gatggatgtt cttgagtttc tcttgagcat
    13381 caatcaaacc ggacttgaca ttacgtggca ggtcaatctg actaatatct ccattgacaa
    13441 tcatcttaga atgaaaacct aaacgagtca agaacatctt catctgcatg atggtcgtat
    13501 tttgcgcctc atcgagaatg acaaaggcat catccaaggt ccgtccacgc atataggcaa
    13561 ggggcgcaat ctcgataatt tcacgctcca tgagtcgagt tgtttggtct ttccccagaa
    13621 tctgatacaa ggcatcataa acaggtctaa ggtaaggatc taccttctcc ttaagatcac
    13681 ccggaagaaa acctagactc tctcctgctt ccaccgctgg acgtgtcaag ataatccgct
    13741 tgacttgccc acgtttaagg gcagtcactg ccaaagtaac tgcaagaaag gtcttccccg
    13801 tccctgcagg cccaattcca aaggtcacat catgctgttt gacactgtcc acataaagtt
    13861 tttgacctaa ggttttgacg cggatcggtt tcccagtatt atctttgata atttcttctt
    13921 cgtaaagggc gacaaactta tcaatttcat cgtttttgac catgctaatt gcagtcacca
    13981 catctggcgt accaacggtc atcccacggt tcaccaagac catgagagct tgaataacct
    14041 gacgggcttc ctcacaagca gactcttctc ccaaaacctg gacaatctcc gtacgagcat
    14101 gaatcaccac atccagctct tcttccatca aacgaagatg acgctcattg gaaccaaaaa
    14161 gatgaaacag gtcatctgga tgactcagtt gaatgtctat tgaatgttcc ttcaaataaa
    14221 gaacctctct aatcctttta tttcttttta ttatagcaga gggatggaga aattactagc
    14281 ccaaacccaa tgaataaatg ctagtgttct agatattcct gccaaatgct gtcaaaatct
    14341 cctaggttaa aagagaaact ggcatgctcc tccaaaaagc gactgacctc atcaaaatca
    14401 tctgtatgtt ttggaaaagc tgcctcttca aaagcgagat ctgccaaaat tgctttggga
    14461 ctgttacttt taggattgcg ctcggtcatg agccaagtgt aaaatgattt tctcataagc
    14521 ctccctaaat caactctgta ccaaactggt cctgcttgat tttaccagcc ttcataagac
    14581 cacctaaagc tttcttgaac tgacctttag aaatgccaaa ggttgccttg atgtcgtctg
    14641 gagatgactt gtcatttaag gtcatgaaac cgccattgct ttccaaataa gtcaaaatca
    14701 tctgagcatc gttttccaac atttcaaagg agcgtggttt gagggagagg ttcaaagtgc
    14761 ggtccacttc acggaaacca ataacgcgcg catctaatac ttgccccaaa cgtggctctg
    14821 cgtaacgctc gctaggatga ataaaaccaa gcatattatt ttctggtagg taaacaaaag
    14881 ttcctgacag cttgagacgg taaacaatgg ctggccagtt ttggttctgc atgttgttgt
    14941 aggcaggacg agcgagacgt tggaagtctt cttgataagc caagaggccc cagatacggt
    15001 ctttcttatc cacttcaaga cggatgtaga gttggtcgcc cttcttaggc cagagttcct
    15061 tgagctcagg gagaatatcg agtgacacaa cgatttcctt gtcaggaagg cctgtatcca
    15121 caaagacacc caagtcctta cgaacctctg tgacacgtcc ccaaccaaat tggtcctgag
    15181 tggcagtcac ttctaaggtt gtcaggcgga gtttttgctt catatccgtg tatgcaaaac
    15241 ctttgaccgt atcccctact gtatgttggc cctcttcctt agcaagagca taggtttgac
    15301 catccttttg cacaaagtaa aaacggtcat tttcatcgat gatcagtcca acgataaaac
    15361 ttgcaagatt tgtattcata tttccttctt tcgaataaaa ctcagccagc aatgccaact
    15421 gagtttttct gtttattttt agacttccaa aagttctttc tctttgttag cagtcatgtc
    15481 gtcgatgtgt ttaacagcat cgtctgttac tttttgaata tctttttcaa gagtcttcaa
    15541 ttcgtcttca gtgatttctt ttgctttttc ttgtttctta gcttcgtcca tagcatcgcg
    15601 acggatattg cggacagcca ctttagcatt ttcgccgacc ttcttcactt ctttagcaag
    15661 gtcacgacga gtttcttctg taagagctgg gataaccaag cgaatcacag aaccgtcatt
    15721 agccggtgtg ataccaagat cagaagcgtt caaggcacgt tcgatgtctt tcaatgaaga
    15781 cttgtcaaat ggtgttacca acaaaacacg cgcttctgga atcgtaattg aagcgatttg
    15841 gttaagagga gtttcgactc catagtattc tacatgtaca cggtcaagca agcttgcatt
    15901 ggcacgacca gcacggatac caccaaattc acgagcaagt gattggtgag actgggtcat
    15961 tctctcttta gctttttcaa taattacgtt agccatattc tttcttattc cttttcttcg
    16021 atattatttg aaactgttgt tccgatattt tcaccaaata cgacacgttt gatgttgcct
    16081 gattggttca tgttgaagac aaccaagtca atgtcgttgt ccattgagag ggttgaggct
    16141 gttgagtcca tgatacgaag acctttgttg ataacatcac ggtgggtcaa ttcttcaaac
    16201 ttaacggctg tcttgtcctt cttaggatcg gcattgtaca caccatcgac gccattttta
    16261 gccatgagga tggcatctgc ttcgatttca gctgcacgaa gggccgctgt tgtatctgtc
    16321 gagaagtatg gtgaaccaat tccagcacca aagataacga tacggccttt ttcaaggtga
    16381 cgaagggcac gtccacggac ataaggctct gccacttgtt gcatagcaat agctgtttgt
    16441 acacgcgtat caaccccaac ttgttgcaat gaatctgcca tcacaagagc attcataaca
    16501 gtcccaagca ttccagtgta atctgcctga acacggtcca tacctgcttc tgctgcaggt
    16561 tctccacgcc agagatttcc tccaccaata acaagggcaa tttcgatacc taagctatga
    16621 acttcttgaa tctcttttgc gattgtttga actgtttgga tatcaatccc tacgccacgt
    16681 tcaccggcaa gggcttcacc tgataacttg attaaaatac gtttatactt gggattcgcc
    16741 attttcactc tccttctttc atcctaccta ttttatcaca atttctaaga tttttatagt
    16801 atcatgaaca attctttcaa aaaaattaga cagtcaaaaa ttcctctaag tcggcaaggg
    16861 cacgctctgc aattttttca taacgagcct tcttatcacg gatacgctcg ccttccaact
    16921 ccttgatgat cccaaaattg acattcattg gttggaaatg tttgctgtcg gcatgggtaa
    16981 tgtaatgagc taagcttcca atcgctgtcg tctcggggaa aataacctcg ctttcttcct
    17041 tgaagagacg agctgcgtta attcccgcaa ctaagcccga agccgccgac tcaacatagc
    17101 cttccacccc cgtcatctga ccagcaaaga agagatttgg ttgtttcttg gaacggtaag
    17161 tctgctcaag aagatttggt gaatccatgt aagaattgcg atgcatgaca ccataacgga
    17221 caaactccgc attttcaaga cccggaatca tttggaagac acgcttttgt tctccccatt
    17281 tgaggtgggt ctggaaacca acaatattgt ataggctacc agctgcatta tcctgacgaa
    17341 gttgcacaac cgcataaggt gttttaaatt ctccatcacg aggtcctgtg tagtcgtccg
    17401 gatactcaag accgactggc ttcatagggc cataaagcat agttttaatg ccacgtttgg
    17461 ccataacttc gattggcata catccttcaa agtacttttc tttttcaaaa gaattgagcg
    17521 gtgcttcttc cgcattgacc aaggcttcat ggaaatccat aaactcttgc ttggtcattg
    17581 gagcattgag ataggctgct tctcccttat cataacgaga tttgagatag accttactca
    17641 tatcgatagt gttgacatcg ataataggcg ctgctgcatc gtagaaatag aagccatcgc
    17701 cattattaag ggcatgaatc ttttcagcca gggcatcgct agtcaaggga ccagtcgcca
    17761 caactgtaat aacatctgtt ggcaattctg taatttcatc acgcaccact tcaatcaagg
    17821 ggtggttgac cactttttcg gtcaccattt gagagaaacc atcacgatcc accgcaaggg
    17881 ctccaccggc aggaacacgt gtagcctcag cagattccaa gataacagaa cccaagcgac
    17941 gcatttcttc cttgagaaga ccaactgcat ttatcaaagc atccccacgc aaagaattgg
    18001 aacaaaccaa ctcagcaaaa ttgtctgttt tatgctgggg tgtagacttg acaccacgca
    18061 tttcatatag tttaactgga ataccacgct ctgcgatttg gtaagctgct tcagaacctg
    18121 ccaaaccagc accgataaca ttgatataag attgagacac gacactaata cctctttggg
    18181 agtgtgaagt taagattcac attgaaaaag ccaatcagac ttacaagctt tcgagtttct
    18241 tggctcaggc tgaaaaagtc cacagggctt tttcactccc acaaatcttt ctattttttc
    18301 ttctactagt ataacaaaaa aagggaagaa ggcaaacttc cctgtttagt cattttcttg
    18361 atgtaaagag atagtgagta ttccagttaa gaatcaatta tatgctactc tataaaatct
    18421 tttccacata acggatcgat agggactgtt attctatctc ttgctataac cgtattatct
    18481 aaaacagcat aacattcaac atagtgatct cctttaaact gtgaatcttc gtgatatttt
    18541 attttacctg aaaaaatagc accacgctca caatttcttc taatagcctc agcttcaata
    18601 tttcttactt tccaatagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaat
//
LOCUS       DBEJJE010000040        17817 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEJJE010000040 DBEJJE010000000
VERSION     DBEJJE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.40"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(136..1071)
                     /gene="birA"
                     /locus_tag="ACL3F5_001521"
     CDS             complement(136..1071)
                     /gene="birA"
                     /locus_tag="ACL3F5_001521"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0515294.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1068..1928)
                     /locus_tag="ACL3F5_001522"
     CDS             complement(1068..1928)
                     /locus_tag="ACL3F5_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0515295.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            2036..4198
                     /locus_tag="ACL3F5_001523"
     CDS             2036..4198
                     /locus_tag="ACL3F5_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0515296.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4290..5548
                     /locus_tag="ACL3F5_001524"
                     /pseudo
     CDS             4290..5548
                     /locus_tag="ACL3F5_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            5562..6428
                     /locus_tag="ACL3F5_001525"
     CDS             5562..6428
                     /locus_tag="ACL3F5_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0515297.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRSWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6442..7275
                     /locus_tag="ACL3F5_001526"
     CDS             6442..7275
                     /locus_tag="ACL3F5_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0515298.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7633..9075
                     /gene="gtfA"
                     /locus_tag="ACL3F5_001527"
     CDS             7633..9075
                     /gene="gtfA"
                     /locus_tag="ACL3F5_001527"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0515299.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9213..10406
                     /locus_tag="ACL3F5_001528"
     CDS             9213..10406
                     /locus_tag="ACL3F5_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0515300.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11091..13070
                     /locus_tag="ACL3F5_001529"
     CDS             11091..13070
                     /locus_tag="ACL3F5_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515301.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13137..14633
                     /locus_tag="ACL3F5_001530"
     CDS             13137..14633
                     /locus_tag="ACL3F5_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515302.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14633..15559
                     /gene="oppC"
                     /locus_tag="ACL3F5_001531"
     CDS             14633..15559
                     /gene="oppC"
                     /locus_tag="ACL3F5_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0515303.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15568..16635
                     /locus_tag="ACL3F5_001532"
     CDS             15568..16635
                     /locus_tag="ACL3F5_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515304.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16646..17572
                     /locus_tag="ACL3F5_001533"
     CDS             16646..17572
                     /locus_tag="ACL3F5_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515305.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(17647..>17817)
                     /locus_tag="ACL3F5_001534"
     CDS             complement(17647..>17817)
                     /locus_tag="ACL3F5_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515306.1"
                     /translation="ALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNI
                     KKERTKFVLSRA"
BASE COUNT         5241 a         3167 c         3745 g         5664 t
ORIGIN      
        1 taggctccat aatatctata ggggatttac ccactacaaa tattatagag acaataaaac
       61 ttcagatccg taaaacttaa ttgaattact aatctgaagt tatttttata tcgtttatat
      121 tataattgtg ttattttact tccaactatt gagagaaatt tcgccactat ttagccagat
      181 ttcttttccg ttatcacatt gaactaaaag ttttccattt tctgagatgt ctttagcaag
      241 tcccttgtag tctttttgct ctagtgtgaa agtgacttct tttcctagaa tgaatgactg
      301 ttttttgtat aggtataata gctcttctgc tggtgtttcg aagaaagcac gccagatttc
      361 tatgatcaat tcattccttg ttataggagc tgtagcttta aataagctgg cagctttttc
      421 ttttaattcc tgagggaagt ctttaatagt gaaattgata cctactccaa taatgatatc
      481 tgtgactaag ccagtttcta cagaggtcat tgcttcagta aggattcctc caattttatg
      541 attgtttaga tagatatcat tgacccattt tatatcgaca tctattaaag ttaggttctt
      601 aatggctttg tagacagctc cagctacaag tagtgtgtag gatggtaatt tgtcataggg
      661 gagatttggt ttaagatgga gtgtcatata aattccacct tgtggtgagt agaaggaacg
      721 ttgaaaacgg cctcggcctg ctgtttgata ggaagctaga tagagagtat ttgcttcatg
      781 gcctaaatca attgcttctt ttgcatctag ttgtgttgat tttgtttcgg gtttaaagct
      841 gactttaatt ggaagatttt cttctagaat ctctggaaga ataaggtcac cattcattag
      901 tttatatcct ctatttttga tactattaat ttcaatgcct tcttgttcta gtcgcttgat
      961 agctttccaa attgatgttc ggcttaggga tagtttttct gcgatttttt ctccgctgat
     1021 atagtcggtt tctttagata ggatttggta gacagcttgg taggatttca taatgttgcc
     1081 tttctcacta gttggtattg agagtattct tttcttgtat gacttggaga ctgattaaag
     1141 tattgtttat aagctttcga aaaatggagt ggatctgaaa aacctaccga gtatgcaatt
     1201 accttgatgg actcttgggt attttcgaga agttgtctag ctcggtgcat tcgaacgtag
     1261 agtaggtatt ctttgggtga taaggtatta aattctttga atacgcttga taagtagctt
     1321 ctgtgaacgg atagttcttt tgctaaatct tgaattgtaa gtgattgagg atagtggcta
     1381 tcaattaatc gtttgcattc aagatagagt tggtgggttg atgaaatatt cttttttttc
     1441 tgattgggag caatagttcc cagatgaaac atcagttcat gaagttgtcc catgatatgg
     1501 agttgagcta attcacttga ttttgtaatc tgagcgaagc ggacaatgtc tgagatgagt
     1561 tttgcagtag tctgggtatg acaagtttca gattggatga gataggattg atcagaaatt
     1621 tgagaaagag caaaataatc aggggatttc cctccagtga ttcctaacca gtagtaggcc
     1681 caaggttctt tactatctgc ttgataaaag gttagttcct ctggttttaa tagaaagaaa
     1741 tctccttctt ttaaatcaac aattttaccc ttgtaatgaa attttccttg tcctttacta
     1801 atgtaatgta ggacgtatgt atcacgaatg gctggaccaa aagagtaatt aggtgtgcat
     1861 tcctcatatc cataaaagct tagggcaagg tcaattgttc cagtctggta ttctgaaaaa
     1921 actagcatgt gctacctcct acctaacatt ttaccatatt cttgagacat ttttctattt
     1981 tggaaagcga tttcaggtga taaaatataa tcaataaagt gatgaggtga agtaaatggg
     2041 agttaggata gagaataatc tattttatgt tgagagtaaa aatctaagtt tgattattga
     2101 aaatcgaaat ggctacttac ttttgaaaca tttaggaaag actattaaga actataaagg
     2161 ttccaatagt gtttatgaac gagaccatgc cttttcagga aatccaacgg ctactaatcg
     2221 aacctttagt ttagatactc agcgacagat ttttggacaa catggcttag gagattttag
     2281 gaaaccaact atacaggttc agcatagtgt aactgaagta acagactttc gatttgtaga
     2341 agcaaagatt ttaaaaggtc agaatggtcc acagggctta ccttctccac atagcatgga
     2401 cgatacagag actcttgtct taatgttaga agattctaag gctcaactta gtctgacttt
     2461 gtattatact acttttaata atgatgcgac tattgctagc tacagtaaat tagataataa
     2521 tagtaatcag gaagttgtca tccataaaga tttttctttt atggctgatt ttccagctgc
     2581 agattacgaa atagtaactc tgcagggtgc ttatgctcgt gaaaagactg ttagacgtca
     2641 acaggtagaa caaggaatct tttcgattag ttcaaaccga ggtgcttctg gtcatgctca
     2701 aacaccagct cttctactat gcgaacaagg agtcacagag gatgctggga atgtgtttgc
     2761 tattcaacta atgtatagtg gcaactttga agcttttgtt caaaaaaatc aattgaatga
     2821 agttcgggtg gctattggca ttaatccaga aaacttttct tggaagttag cccctgagga
     2881 atactttgaa acaccggtag ctttagtgac tcattcagat cagggattaa ctggtattag
     2941 tcatgaaagt cagaattttg tactgaagca cattattcta agtgaatttt ctaaaaaaga
     3001 acgtccaatt ctaatcaata actgggaagc tacttacttt gactttcaga gagaaaaact
     3061 gttagagtta gcagatgaag ctaagaaagt tggcattgaa ctttttgtat tagatgatgg
     3121 ttggtttggc aatcgttttg atgataatcg tgctttaggt gattgggttg ttaatgagga
     3181 aaaactgggt ggaagtctag aaagtctgat ttcagctatc catgaaagag gtttgcagtt
     3241 tggactttgg ttagaacccg aaatgatttc tgtagatagt gatttgtatc gtcaacatcc
     3301 tgactgggct attcaggttc ctgattatga gcatacttat tctcggaatc aattagtact
     3361 taatcttgcc aatcctcagg tagtagaata cttgaaaagt gtcttagatc aactcctatc
     3421 ttatcatgag attgattaca ttaaatggga tatgaaccgc aatatcacta agctagggaa
     3481 tggattaact tatctagaga cacagatgca atctcatcag tacatgctgg gactttacga
     3541 actcgtttct tatctgacag agaagcacag ccatattctc tttgagtcct gctctggtgg
     3601 tggtggacga aatgatcttg gtatgatacg ctatttccca caagtctggg ctagtgataa
     3661 tactgatgcc attgcacgtt taccaattca atacggttca tcctatctct atccaaccat
     3721 ttctatgggg gctcatgtgt cagcagtacc gaatcatcag atgggacgaa tgacaccatt
     3781 agaaacacgt ggccatgtag caatgatggg aaatttgggc tatgagcttg atttgacaaa
     3841 tttatcagat gaagagaaag ctacgattgc taatcaggtg aacttgtata aagaattacg
     3901 accagtagtt cagttaggac agcagtatag actaattaat cctgatactg catccaatga
     3961 agcagctgta caatttaatt acggaaatca aacgattgta acctacgttc gcgttttatc
     4021 tgttgtagag accatggaaa caactttaaa attaaaagat ttggatgaag agggactata
     4081 taaattacag gaaaatggcg aagtttactc aggtgcagaa ctaatgtatg cgggcttaac
     4141 tgttatctta tcccaaggag attttttgag tagacagtat atttttagaa aactatgata
     4201 tgtactgacc ccaaaagtta gatttattct gtctaacttt tggggtgcag ttcaataagg
     4261 gtgtataaat ttataaagga ggctttctaa tggaatggta taaaaaatcg gacttcttgc
     4321 aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta aatctgcgga
     4381 tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga
     4441 aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc
     4501 aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa
     4561 tatttaccca cagtccatcg aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt
     4621 gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa
     4681 cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact acaacaaaga
     4741 taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg aacagttagt
     4801 caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag atgcttggac
     4861 actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa
     4921 tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga ttatgaaaga
     4981 tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga actgggaagg
     5041 tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa
     5101 tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga ttgggacctt
     5161 catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag acttggcatg
     5221 gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg aatatatgac
     5281 ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag cgatcgaagg
     5341 ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg cctttacgga
     5401 tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc ataccttgac
     5461 catgaactat gtcttgaccg gtgataaaga aggcatggtc aatgatttga atgccttctt
     5521 taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa gtattacaaa
     5581 aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg
     5641 tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg acttataact
     5701 acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa ttcatgaatg
     5761 cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt gcactcggga
     5821 tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc cgttcttggt
     5881 tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag caagtcttca
     5941 actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa accagtcttt
     6001 tagggactaa gtggggagca atctttgcgg ctgtctttgt ccttctttgg caaggggtgg
     6061 ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag attacagagg
     6121 cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa ttgccttact
     6181 tgctaccaag tgtctctata gtctttatcc tagccttaaa aggtgggctg actgcctttg
     6241 accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca cttgggctct
     6301 tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc attgccgtaa
     6361 tcttgttctt cttaattgta gtgatttcga tcatccaatt gagagtatct aagaaatttg
     6421 aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat tggcaaatac
     6481 attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac cctctttagt
     6541 tccttcaaac ccactaagga tattgtagat aatttctttg gctttccaac caacttcaca
     6601 tgggacaact ttagccgtct cttagctgat gggattggag gctattattg gaactctgtc
     6661 gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc agcctactcc
     6721 atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct cttaatcctc
     6781 ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat gagtaaactc
     6841 ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat tccacagacc
     6901 ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga tgaagcagca
     6961 gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc aatgatgaaa
     7021 ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga cttcatgttg
     7081 ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt ccaatacaac
     7141 tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt ggtcggcatt
     7201 atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg aatgagcaac
     7261 ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
     7321 tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa ccatacctac
     7381 ggcaaggtga agctgacgtg gtttgaagag attttcgaag agtataagaa gagctcatgg
     7441 aatctatagt ctttgacaca gaggaagagt ttagcttgtt gataattcta tgtagaaaac
     7501 aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg ataaatagag
     7561 atttaaaatg aattttattt atgaagccag atcatatgag acttggcttc aattagaaaa
     7621 aggagagtaa tgatgccaat tcaaaataaa accatgttga ttacctattc tgatagcctt
     7681 ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga tgctattgga
     7741 ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc gccagttgac
     7801 tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt aggtgagaga
     7861 tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa gtattataag
     7921 gactatcaag aaaaacatga agccagtgaa tttaaagctc tctttttaaa ctgggataag
     7981 ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa gcgtaaggat
     8041 cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt gtggaatacc
     8101 tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga atttatccgt
     8161 aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga tgcctttgct
     8221 tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat ttgggattta
     8281 ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc tgagattcat
     8341 gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta tgattttgct
     8401 cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt ggctaagtgg
     8461 ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg gattggagta
     8521 gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa tgaactctat
     8581 aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa cttagatatc
     8641 taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa gtattttctc
     8701 gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt gggtctatta
     8761 gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa tattaatcgt
     8821 cattactata gcaacgagga aatagcaaaa gaagtgcaac gacctgttgt gaaggccctt
     8881 ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaggg gactactgag
     8941 atagagacac caacagctca cagcattgta atcaaacgtc aaaataaaga taagtccgta
     9001 acagcagtag tagaaattga tttgcaaaat cagacttatc gggtaattga gaatggagtt
     9061 gaagtatcat tttgaagcct tgatatggtg gataaaatag ggtttttatt ttggaaaacg
     9121 tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt actattatct
     9181 gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt attgaaaagc
     9241 tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctgagt atctttttac
     9301 ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt tttacaggag
     9361 acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt tttcttagct
     9421 atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct tcagtaggaa
     9481 tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat aaattctttc
     9541 gattgatttt gcagtttgtc ttgtttggta gtgtcttgtc agctgctttt gccagtttag
     9601 aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat atgcaggtgt
     9661 ggcatcagaa ccgggcagaa gtgaccttct ttaatcctaa ttattatgga attatttgtt
     9721 gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat tggttgaaag
     9781 tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact cagaatcgaa
     9841 ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact attaaaaact
     9901 ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc ctcttttcta
     9961 gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc atttctatct
    10021 gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg ccattgacct
    10081 atatgaactc ttatcctcgg atacatgctc cttatcatga acatgcccac agtctttata
    10141 ttgatacgat tctgagttac ggaattgtgg ggactatttt attagttttg tcttctgttg
    10201 ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg attatcggcc
    10261 tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg gctctcttct
    10321 ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg gagcatcgaa
    10381 tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta ccttgggtag
    10441 gagatttttt atacgatggg catgtcgtgc atctgaggtg taagtcctct gtagggctcc
    10501 actaccggtg aatacaatag cgctccccaa gcctgactat cgtgaggtag cggattaaaa
    10561 tggtctgggg atagatcgtt ttaagtctga cgcaggaaat aagaattgtc agagaaagca
    10621 atagtgaaat cgtaggctat gaatagaaac gtgatagcga ggagcatata gtggataagg
    10681 tagcgagaaa ttttaaagta taaaagatag tcttaatcta tatatgtaaa tcacaaaagt
    10741 aattgaattc gggataaggt tggtgtgaaa agacatagta aactgaatct tgaatactag
    10801 aatgatactt ctacaatatt gttataattt aatttgaatt ccaaaatcac attgttccgt
    10861 ccgtatttca ttttactgta tgtcttccta aactccaaag tttctgcgtc aaatttccta
    10921 ttttcactgt agtctttgac acttcgaacg acaatttgaa tcatatattc aaaaaaaatg
    10981 aaaaatttgt gccaacaagc ctaaatattc tgaaaatttg tttgattttt aatggataat
    11041 gtgatataat ggttgtcaat ctataattca cataaacaga ggagtagaaa atgaaaaaaa
    11101 atcgtgtatt tgctacagca ggtcttgttt tattagcagc aggtgtactt gcagcatgca
    11161 gttcttcaaa atcatctgat tcatcagccc ctaaagctta tggctatgtt tatacagcag
    11221 acccagaaac cttggactac ctgatttcaa gtaaaaatag tacaacagta gtgacttcaa
    11281 atgggattga tggtttattc actaacgata attacggtaa tcttgctcct gcagttgcag
    11341 aggattggga agtctctaag gatggtttga cctacactta taagattcgt aaaggggtta
    11401 aatggtttac ctctgatgga gaagaatatg cagaggtgac ggctaaagat ttcgtgaacg
    11461 gtttaaaaca cgcagcagat aaaaaatcag aagctatgta tttagctgaa aattcggtta
    11521 aaggcttggc agattatcta tcaggaactt caacagattt ttcaacagtt ggtgtcaagg
    11581 cggttgatga ttatacgtta caatacactt tgaaccagcc tgaaccgttc tggaactcta
    11641 agttgaccta ttctattttc tggcctctga atgaagaatt cgaaacatca aaaggaagcg
    11701 attttgctaa accaacagat ccgacatcct tgctttataa tggtccattc ttgttgaaag
    11761 ggttgactgc aaaatcttct gtagagtttg taaaaaatga gcaatattgg gataaagaaa
    11821 atgtccacct agatactatc aatctagctt actatgatgg atcagatcag gagtcgctag
    11881 agcgtaactt cactagtgga gcttatagtt atgcccgtct ttaccctacc agctccaact
    11941 attctaaggt tgcagaagaa tacaaggaca atatctatta cacacaatca ggctctggga
    12001 ttgctggtct gggtgtgaat attgatcgcc aaagttacaa ctatacttct aaaactacag
    12061 attcagagaa agtagctact aagaaggcat tgcttaacaa agatttccgt caagccttga
    12121 attttgctct tgatcgctca gcttactcag ctcaaatcaa tggtaaagat ggagcagctt
    12181 tagcagttcg taatttattt gtaaaaccag actttgtttc agctggtgag aagacctttg
    12241 gtgatttagt cgctgctcaa cttcctgctt atggtgatga gtggaaaggt gtgaatttag
    12301 ctgatgggca ggatggttta ttcaatgctg acaaggccaa ggcagagttt gcgaaagcta
    12361 agaaagcttt agaagcagac ggcgttcagt ttcctattca tctggacgtt ccagtagacc
    12421 aagcatcaaa aaactacata tctcgtattc agtcctttaa acaatctgta gaaacagttc
    12481 ttggtgttga aaatgtcgtt gttgatattc aacaaatgac aagtgatgaa ttccttaata
    12541 ttacttacta tgctgccaat gcttcatctg aggattggga tgtatcagga ggagtttcat
    12601 gggggccaga ctatcaagac ccatctactt acctggatat tttaaaaaca actagcagtg
    12661 aaactacaaa aacatattta ggatttgata atccaaatag cccttcagta gttcaagttg
    12721 gtttgaaaga atacgataaa ttagttgatg aagctgccag agagacaagc gacttgaatg
    12781 tccgttatga aaaatatgca gcggctcaag catggttgac agatagttca ctctttattc
    12841 ctgctatggc ttcttctggt gcagcaccag tgctttcacg aattgttcca tttactggag
    12901 cttctgcgca aacaggctct aaggggtcag atgtttactt caaatatttg aaattacaag
    12961 ataaagcggt gactaaggaa gagtatgaaa aagctcgtga aaaatggttg aaagaaaaag
    13021 ctgaatcaaa tgagaaagct caaaaagaat tggcaagtca tgtgaagtaa ataatttcta
    13081 atagaacttt ctctccatga ggagaaggtt cttttgggat ttttaaagga aataatatga
    13141 aaaaatatat ttttatgcgt gttttgcggt cattggtttc gattttctta gtaacgactt
    13201 tgacctacac gattatctat accttggttc ctcgaaaatt gattttcaag caggatccta
    13261 actataataa aattgcgaca acggctgata aacgtgataa ctatgaaaat actgtgtttg
    13321 agcgtatggg ctacattgag tattacgata ctaaagagtt gcaagaaaag gcaagtagca
    13381 tggattcttc tgtaacagta gaagcaaatg cgaccaataa agctatttat gaaaagtaca
    13441 tcaatcaatt aggtcatggt tggactttgg gagaatttac tgaaagtggt caattctatg
    13501 ctactcgtga aattccaatt tttgaacgtg tttttcactt ctatgctaac ttgattgaca
    13561 ttgaccatac aaataaaatc caagaccctg aaaatccaga cttgaaacgc taccttcgtt
    13621 ttgaaaatga tccagctatc ggatggtcat tggtcggttc aggaactaaa cataaatatc
    13681 tcttgtactt taacagtcag ttcccatttg ttcatcaaaa ctttgtgaac ttgaatttag
    13741 gtgactctta cccaacctat gctaatacac cagttcttca ggttattact caaggtcaag
    13801 gacaaaccaa aactgcccaa gttcagttcc caacaggtaa gaaaacgtct tctgtaaata
    13861 tttactcaag aacctacaag tcacctagtc aggctgactc tcgtgaagta gctagctatg
    13921 ggaaagatga tccttataca gcgactgaaa gtaattacca atatccatct atgattgtca
    13981 gctctgctat tactggtttg attggtttgg ttcttgccta tgctcttgcc gtgccacttg
    14041 gttcagccat ggctcgtttc aagaacactt ggattgatag cctctcaaca ggggctttga
    14101 ccttcttgct tgctcttcca acgattgcct tggtttacat cgttcgattg attggatcat
    14161 ctattgccct tccagattca ttccctatct tgggagctgg agattggcgt tcttacgttt
    14221 taccagcagt catccttggt ttgttgggtg ctcctggtac agccatttgg attcgtcgtt
    14281 acatgattga cttgcaatct caagactttg ttcgtttcgc tcgtgcaaaa ggtttgtctg
    14341 aaaaagaaat ttcaaacaaa cacatcttta aaaatgccat ggttccgctg gtttcaggaa
    14401 ttcctgctgc cattattggg gttatcggtg gtgcaaccct tactgaaaca gtcttcgcct
    14461 tcccaggtat gggtaaaatg ttgattgact ctgtaaaagc atctaataac tctatggtcg
    14521 ttggtcttgt cttcatcttt acatgtattt ctatcttctc acgtcttttg ggagatattt
    14581 ggatgactat tattgaccca cgtattaaat tgactgagaa aggaggcaaa taatgtctac
    14641 aatcgataaa gaaaaatttc agtttgtaaa acgtgacgat tttgcctctg aaactattga
    14701 tgcgccagca tattcttact ggaaatcagt gtttaaacaa tttatgaaga aaaaatcaac
    14761 tgtagtcatg ttgggaatct tggtagccat cattttgata agtttcatct acccaatgtt
    14821 ttctaagttt gatttcaatg atgtcagcaa ggtaaacgac tttagtgttc gttatatcaa
    14881 gccaaatgcg gagcattggt tcggtactga cagtaacggt aaatcgctct ttgacggtgt
    14941 ctggttcgga gctcgtaact ccatcctcat ttctgtgatt gcgacagtga ttaacttggt
    15001 tatcggtgtt tttgtcggtg gtatttgggg tatttcaaaa tcagttgacc gtgtcatgat
    15061 ggaagtttac aacgtcatct caaacatccc acctcttttg attgttattg tcttgactta
    15121 ctcaatcgga gctggattct ggaatctgat ttttgccatg agcgtaacaa catggattgg
    15181 tattgccttc atgatccgtg tgcaaatctt gcgctatcgt gacttggaat acaacttggc
    15241 gtcacgtact ttgggaacac caaccttgaa gattgttgcc aaaaatatca tgcctcaatt
    15301 ggtatctgtt attgtgacaa ccatgactca aatgcttcca agctttatct catacgaagc
    15361 cttcttgtct ttcttcggtc ttggattacc gattacagtg ccaagtttgg gtcgtttgat
    15421 ttcggattat tcacaaaacg taacaaccaa tgcttacttg ttctggattc cattgacaac
    15481 ccttgtcttg gtatccttgt cccttttcgt agttggtcaa aacttagcgg atgctagtga
    15541 tccacgtaca catagatagg agtagaaatg acaaaagaaa aaaatgtaat tttgactgct
    15601 cgcgatattg tcgtggaatt tgacgttcgt gacaaagtat tgacagccat tcgcggcgtt
    15661 tcccttgaac tagtcgaagg agaagtatta gccttggtag gtgagtcagg atcaggtaaa
    15721 tctgttttga caaagacctt cacaggtatg ctcgaagaaa atggtcgtat tgcccaaggt
    15781 agtattgact accgtggtca ggacttgaca gctttatctt ctcacaagga ttgggaacaa
    15841 attcgtggtg ctaagattgc gactatcttc caggacccaa tgactagttt ggaccccatt
    15901 aaaacaattg gtagtcagat tacagaagtt attgtaaaac accaaggaaa aacagctaaa
    15961 gaagcgaaag aattggccat tgactacatg aataaggttg gcattccaga cgcagataga
    16021 cgttttaatg aatacccatt ccaatattct ggaggaatgc gtcaacgtat cgttattgcg
    16081 attgcccttg cctgccgacc tgatgtcttg atctgtgatg agccaacaac tgccttggat
    16141 gtaactattc aagctcagat tattgatttg ctaaaatctt tacaaaacga gtatcatttc
    16201 acaacaatct ttattaccca cgaccttggt gtggtggcaa gtattgcgga taaggtagcg
    16261 gttatgtatg caggagaaat cgttgagtat ggaacggttg aggaagtctt ctatgaccct
    16321 cgccatccat atacatggag tctcttgtct agcttgcctc agcttgctga tgataaaggg
    16381 gatctttact caatcccagg aacacctccg tcactttata ctgacctgaa aggggatgct
    16441 tttgctttgc gttctgacta cgcaatgcag attgacttcg aacaaaaagc tcctcaattc
    16501 tcagtatcaa agacacattg ggctaaaact tggcttcttc atgaggatgc tccaaaagta
    16561 gaaaaaccag ctgtgattgc aaatctccat gataagatcc gtgaaaaaat gggatttgcc
    16621 catctggctg actaggagga aggaaatgtc tgaaaaatta gtagaaatca aagatttaga
    16681 aatttccttc ggtgaaggaa gtaagaagtt tgtcgcggtt aaaaatgcta acttctttat
    16741 caacaaggga gaaactttct cgcttgtagg tgagtccggt agtgggaaaa caactattgg
    16801 tcgtgctatc atcggtctaa atgatacaag taatggagat atcatttttg atggtcaaaa
    16861 gattaatggt aagaaatcgc gtgaacaagc tgcggaattg attcgtcgaa tccagatgat
    16921 tttccaagac cctgccgcaa gtttgaatga acgtgcgact gttgattata ttatttctga
    16981 aggtctttac aatcaccgtt tatttaagga tgaagaagaa cgtaaagaga aagttcaaaa
    17041 tattatccgt gaagtaggtc ttcttgctga gcacttgact cgttaccctc atgaattctc
    17101 aggcggtcaa cgtcaacgta tcggtattgc ccgtgccttg gtcatgcaac cagactttgt
    17161 tattgcagat gagccaattt cagccttgga cgtttctgta cgtgcccaag tcttgaactt
    17221 gctcaaaaaa ttccaaaaag agctcggcct gacctatctc ttcatcgccc atgacttgtc
    17281 ggttgttcgc tttatttcag atcgtatcgc agttatttac aagggtgtta ttgtagaggt
    17341 tgcagaaaca gaagaattgt ttaacaatcc aattcatcca tatactcaag ccttgctttc
    17401 agcggtacca atcccagatc caatcttgga acgtaagaag gtcttgaagg tttacgatcc
    17461 aagtcaacac gactatgaga ctgataagcc atctatggta gaaattcgtc caggtcacta
    17521 tgtttgggcg aaccaagccg aattggcacg ttatcaaaaa ggactaaact agtaatggtt
    17581 ttataatttc catgtcaatt tttatggaaa ttaggctctt tgtcaactgt agtgggttga
    17641 agtcagctaa gctcgagaaa ggacaaattt cgtcctttct tttttgatgt tcaaagcgat
    17701 aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc gcttgataag
    17761 tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt gaagggc
//
LOCUS       DBEJJE010000041        17469 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEJJE010000041 DBEJJE010000000
VERSION     DBEJJE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.41"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..618
                     /locus_tag="ACL3F5_001535"
     CDS             <1..618
                     /locus_tag="ACL3F5_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515307.1"
                     /translation="KTYILDISAPYSELDYNKYWYVLHTLIYMPMIFPIQILYQNLRE
                     ALIEDNNNGWNIMVINTNNLVKIIYIKVTINIVRCFICYFVYTIFSLIQLGGMGTDML
                     LTNIIFPNIMSFLLFLPIAIFMQICCIRFDSILAKALPNILLILIVLITFQSDWNIFI
                     PATYYYTEIQSTTNLGIKLLVCIWIMGFEFSLLPKLIKLKEQNLV"
     gene            1161..1382
                     /locus_tag="ACL3F5_001536"
     CDS             1161..1382
                     /locus_tag="ACL3F5_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0515308.1"
                     /translation="MYRCLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            1828..2130
                     /locus_tag="ACL3F5_001537"
                     /pseudo
     CDS             1828..2130
                     /locus_tag="ACL3F5_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2286..3515
                     /locus_tag="ACL3F5_001538"
     CDS             2286..3515
                     /locus_tag="ACL3F5_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0515309.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNRLLK"
     gene            3535..6231
                     /gene="ppc"
                     /locus_tag="ACL3F5_001539"
     CDS             3535..6231
                     /gene="ppc"
                     /locus_tag="ACL3F5_001539"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0515310.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6314..6531
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6644..7648
                     /gene="trpX"
                     /locus_tag="ACL3F5_001540"
     CDS             6644..7648
                     /gene="trpX"
                     /locus_tag="ACL3F5_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515311.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSIGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7717..8583
                     /locus_tag="ACL3F5_001541"
     CDS             7717..8583
                     /locus_tag="ACL3F5_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515312.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8580..9338
                     /locus_tag="ACL3F5_001542"
     CDS             8580..9338
                     /locus_tag="ACL3F5_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515313.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLNQEEKAKMKISDYYQLFE"
     gene            9428..11188
                     /gene="dnaG"
                     /locus_tag="ACL3F5_001543"
     CDS             9428..11188
                     /gene="dnaG"
                     /locus_tag="ACL3F5_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0515314.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKVGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTVIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENGENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            11191..12300
                     /gene="rpoD"
                     /locus_tag="ACL3F5_001544"
     CDS             11191..12300
                     /gene="rpoD"
                     /locus_tag="ACL3F5_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0515315.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12314..12643
                     /locus_tag="ACL3F5_001545"
     CDS             12314..12643
                     /locus_tag="ACL3F5_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0515316.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12677..13801
                     /gene="cpoA"
                     /locus_tag="ACL3F5_001546"
     CDS             12677..13801
                     /gene="cpoA"
                     /locus_tag="ACL3F5_001546"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0515317.1"
                     /translation="MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKV
                     AGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGR
                     KIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPR
                     EKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLA
                     EELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLF
                     LLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQAN
                     PAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            13817..15142
                     /locus_tag="ACL3F5_001547"
     CDS             13817..15142
                     /locus_tag="ACL3F5_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0515318.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15173..15349
                     /locus_tag="ACL3F5_001548"
     CDS             15173..15349
                     /locus_tag="ACL3F5_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0515319.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15408..15542
                     /locus_tag="ACL3F5_001549"
     CDS             15408..15542
                     /locus_tag="ACL3F5_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0515320.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15606..16916
                     /gene="obgE"
                     /locus_tag="ACL3F5_001550"
     CDS             15606..16916
                     /gene="obgE"
                     /locus_tag="ACL3F5_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0515321.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVTNKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEVYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16926..17084
                     /locus_tag="ACL3F5_001551"
     CDS             16926..17084
                     /locus_tag="ACL3F5_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515322.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TTKENPSQ"
     gene            complement(17135..>17469)
                     /locus_tag="ACL3F5_001552"
     CDS             complement(17135..>17469)
                     /locus_tag="ACL3F5_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515323.1"
                     /translation="KLLSYSEDLKHHYQLYNKEPEKFFGLIEDNLKQVHPIFQTVFKT
                     FLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKER
                     TKFVLSQA"
BASE COUNT         5370 a         2991 c         3825 g         5283 t
ORIGIN      
        1 aaaacatata ttttagatat ttcggcacca tactcagagc ttgattataa taagtattgg
       61 tatgttttac acactttaat atatatgcca atgatttttc ctatacaaat tttgtatcaa
      121 aatctaagag aggcattgat tgaagataat aataatggtt ggaatatcat ggtgattaac
      181 actaataatc tcgtgaaaat catctatata aaagtaacga taaatatcgt gagatgtttt
      241 atttgttatt ttgtttatac aattttttct ttaattcaat taggtggtat gggaactgat
      301 atgttattaa ccaatataat atttcccaat ataatgtcat ttcttttatt tttacctata
      361 gctatcttta tgcaaatttg ctgtataaga tttgattcca ttttagcaaa ggccttacct
      421 aatattttgc tgatacttat tgttttaatc acgtttcaga gtgattggaa tatatttata
      481 cctgcaactt attattatac agaaattcag tcaactacaa acttaggtat taaattatta
      541 gtttgtatct ggattatggg atttgaattt tcccttcttc caaaactaat aaaattgaaa
      601 gaacaaaatc tagtttaaat gttgctcgaa aattaaataa ttgaatacga ttaacaatga
      661 aacaatacaa cgtgagtcat gacttcaaag taattgattt tatgattctg gtttcttacg
      721 cttaattaag caagttgtat tcactttatc aaattgttat tactctaaaa agcgtctaac
      781 agctatagag tgtctgtttg cttctcttta cttttatttt aaataattca ttaaccttcc
      841 gtaagtgccc aataataagg tgtgttgaag aagtctgaga taaaatagtt ctcagtcaca
      901 aaaaaagcta tagattccca ttggtgaaca gctccctgtc aagtagacag taaaataata
      961 taaaatctta agcgacctga ttcctgaatt ccagtggagt caggttgttt tttaaccgtc
     1021 tttcttaata ttgtctcacc tataatagat atgcttatga gaagtgttta ataaattaat
     1081 tttagttcaa aatgtccaat ttggacactt tgaatgattt cttagtttta tatattatac
     1141 ttttctcagg agaaagctag atgtacagat gtttgagaga tttgagggaa gatcacgatt
     1201 tgactcaaaa acaaatagct aaaatacttt cgtttacaaa ctcagcttat gctaaaattg
     1261 aacggggtga gcatacgtta acagcagatg tattggtaac tctctcaaac ttttacgatg
     1321 tcagtacaga ctacctattg ggattgacag attttcctga taaaattcgc tttagaaaat
     1381 aatcacctca atttcataga gtgtgaaaat gaggtgattt tttatttgtt ctttgaaaat
     1441 taaatagtcc aaaatggtac tttcctcatt tgtggagcaa atttgaatgg ctcgccatga
     1501 taagagcgat tttaaaacca tcaataaaat agagcgatac tttatatgcc atgatacaaa
     1561 tgatatacaa tgatacttct ggccgttcag cctgccaacg taaaagagca gcaagtgaaa
     1621 ttcttatgat gacttcatca gtcatgccac gttgaatgtg tgagtttgtt agataaacgc
     1681 aattaatcct caaaaggttc cccgaacctt ttgagttcta cagacgcatc acgtggagtg
     1741 tgtaagcttg ttgctaaaag cgtaaaaacc ttggaacgaa aggaataata gacttcctgc
     1801 gaaacaaaaa tataatacaa taaaactatg aatgatgaag caagtaaaca attgagcgat
     1861 agccgtttca agatccttgt aggtgttcag cgcacgactt ttgaagagat gttagctgtg
     1921 ttaaaaacag cttatcaacg taaacgcgca aaaggtggac gaaaaagcaa attaagccta
     1981 gacgatctcc ttatggtaac tattcaatac atgcgagaat agagcactta tgaacaaatt
     2041 gcggctgatt ttggcattca cgaaagcaac ttaatccgtc ggagtcaatg ggttgaagca
     2101 actcttattc aaaatggttt tacgatttca aattctgcct taattctgta aaaacagtaa
     2161 aattcgaagg attgtaaggt aagagttttt ttctttctga aaaaatggta taatagcaat
     2221 caaaactaga aaataaaacg gaatttggaa cagatttgtc tgtatcctag tagagtggtg
     2281 atactatgaa gattagtaag aggcacttat taaattattc catcttgatt ccctacttgc
     2341 ttttatctat tttgggcttg attgtggtct attcgaccac cagtgctatt ttaattgaag
     2401 aaggcaagag cgccttgcag ttggttcgaa accaaggaat cttttggatt gttagtttga
     2461 tactgattgc cttaatttat aaattgagac tagatttttt gagaaatgag cgactaatca
     2521 ttttagttat attaatagaa atgcttttat tgttcttggc tcgttttatt ggtatttcag
     2581 taaacggggc atacggttgg atttcggttg caggagtaac tattcagcca gctgagtact
     2641 taaaaatcat tattatttgg tatttagctc accgattctc caaacagcaa gaagaaatag
     2701 ctacttatga ttttcaagtt ttgactcaaa atcaatggct tccccgtgct tttaatgatt
     2761 ggcgattcgt tctcctagtt ctgattggaa gtttgggaat tttccctgat ttaggaaatg
     2821 cgactatttt agtcttggtt tccttgatta tgtatacagt tagtggaatc gcttatcgct
     2881 ggttttcaac cattctggcg ctcgtatctg ccgcttctgt ctttgtcttg accactatca
     2941 gcctaatcgg tgttgagacc ttttcaaaaa ttccagtatt tggctatgta gccaaacgct
     3001 ttagtgcctt ttttaatcct tttgccgatc gtgctgatgc aggtcaccag ttagctaatt
     3061 cttattttgc catggtcaat ggtggttggt ttggtctagg tcttggaaac tcgattgaaa
     3121 aacgaggtta tttgccagaa gctcatacag actttgtctt ttctatcgtg attgaagaat
     3181 ttggctttgt tggtgccagt cttattttag ctctcttgtt tttcatgatt ttgcggatta
     3241 tcttggtcgg tattcgagcg gagaatcctt tcaatgccat ggttgcactc ggtgtcggag
     3301 ggatgatgtt ggttcaggta tttgtcaata tcggagggat ttcgggcttg attccatcta
     3361 caggagtaac cttccccttc ttatcccagg gtggaaatag tcttctagtc ttatcagtgg
     3421 cagtagcctt tgtcttaaat attgatgcca gtgaaaaacg cgctaagttg taccgagaat
     3481 tggaaaatca accaatgaac cgtctgttga agtaggataa agaaaggata gtttatgtct
     3541 cttcaaaaat tagaaaattc tagtaataaa agtgttgtgc aagaagaagt cttgattcta
     3601 acagaattac tggaagatat tactaaaaat atgcttgccc cagagacctt tgaaaaaata
     3661 atacagttga aagaattatc aacgcaggaa gattatcaag gtctaaaccg tctagtgact
     3721 agcttatcaa atgatgaaat ggtctatatt tcacgctatt tctctatctt gcctcttttg
     3781 attaatattt cagaggatgt ggatttagct tatgaaatca atcatcaaaa taatattgat
     3841 caggactatt taggtaaatt atctacaacg attaaattgg tagcagaaaa ggaaaatgcc
     3901 gttgagatcc tagaacactt gaatgttgtt ccggttttga cagcccatcc aacacaagtg
     3961 caacgcaaaa gtatgttgga tttaacaaat catattcata gtcttttgcg taaataccgt
     4021 gatgttaagt tggggttgat caataaagat aaatggtaca atgatttgcg tcgttacatc
     4081 gaaattatca tgcagacaga catgattcgt gagaaaaaat taaaagtgac taacgaaatc
     4141 acgaatgcta tggaatatta taacagctcc tttttgaaag ctgtacctca tttgacgacg
     4201 gagtataagc gcttagcgca agcgcatggt ctgaatttaa aacaggctaa accaatcacc
     4261 atgggtatgt ggataggtgg tgaccgtgat ggaaatccat ttgttacagc aaagaccttg
     4321 aagcagtctg cactcactca gtgtgaagtc atcatgaact actatgataa aaagatttac
     4381 caactttatc gtgaattttc tctttcaact agcattgtca acgtcagcaa gcaagtcaga
     4441 gaaatggctc gtcaatccaa ggataactcg atttaccgcg aaaaagagct ttaccgtcgt
     4501 gccttgtttg atattcaatc aaaaattcag gcaactaaaa cctatctgat tgaggatgaa
     4561 gaagttggga ctcgttatga aaccgccaat gatttctaca aggatttgat tgccattcga
     4621 gattctctac tagaaaataa gggcgagtcc ttgatttcag gtgattttgt ggaattattg
     4681 caggcagtag agatatttgg tttttactta gcatcaattg atatgcgaca agactctagc
     4741 gtctatgaag cctgtgtggc agaactcttg aaatcagcag gaattcattc tcgttatagc
     4801 gagttgagcg aagaagaaaa gtgtgacctt ctcttgaaag aattagaaga agatccccga
     4861 attctttctg cgactcacgc agaaaaatca gaattattag caaaagaact agctattttt
     4921 aagacggctc gtgttttgaa agataagttg ggagatgatg tcatccgtca gaccatcatt
     4981 tcacatgcaa ccagcctttc tgatatgcta gaattagcta ttctgttaaa agaagtagga
     5041 ctggtggata cggaaagggc gcgtgttcag attgttcccc tttttgaaac aattgaagac
     5101 ttggatcatt cagaggaaac aatgagaaaa tatctttctc ttagccttgc caaaaaatgg
     5161 attgactcac gaaataacta ccaagaaatc atgcttggct actctgacag taataaagat
     5221 ggcggttact tgtcatcatg ttggaccctc tacaaggctc aacaacaatt gactgctatt
     5281 ggagatgaat ttggcgttaa ggttaccttc ttccatggtc gtggtggtac tgtcggtcgt
     5341 ggtggtgggc caacctatga agccattaca tctcaaccgc tcaagtctat caaggatcgt
     5401 atccgcttga cggagcaggg tgaagtaatt gggaataaat acggtaacaa agacgccgct
     5461 tactataacc ttgaaatgct agtatcggca gctattaacc gtatgattac tcagaagaag
     5521 agcgatacca ataccccaaa tcgttatgaa gccattatgg atcaagtagt ggaccgtagt
     5581 tacgatatct accgtgattt ggtctttggt aatgagcatt tctatgatta tttcttcgag
     5641 tcaagtccaa tcaaggctat ttcaagtttt aatattggtt ctcgtccagc cgctcgtaag
     5701 actattactg aaatcggtgg attgcgtgct atcccttggg tattctcatg gtcacagagt
     5761 cgtgttatgt tccctggatg gtacggggtt ggttcaagct tcaaggaatt tatcaataaa
     5821 aatccagaga atattgctat cttacgagat atgtaccaaa attggccttt cttccaatcg
     5881 cttctttcaa atgttgatat ggttttgtca aaatcaaata tgaatattgc ttttgaatat
     5941 gctaaacttt gtgaagacga gcaagttaag gccatctatg agactatttt aaatgaatgg
     6001 caagttacta agaacgttat cttggctatt gaaggacatg acgaactctt agctgacaat
     6061 ccatatctaa aagctagtct ggattaccgt atgccttact ttaatattct caactatatt
     6121 cagttagagt tgattaaacg ccaacgtcgt ggagaattgt ccagtgatca agaacgattg
     6181 attcatatca ccatcaacgg aattgcgaca ggattgcgta attcaggttg ataattttca
     6241 agagtgaatg ctaaaagtga atatcaaaaa aattctaata gactattgac aagtagttta
     6301 aaaatgatat aatttaacca ttcagaaaag taatcataca aactttttag agagtctgtg
     6361 gtagctgaaa acagataagt ggcaatgatg aaaattgggc tgaatgctat ttagaatttg
     6421 aaattataaa aattcggtaa gcacacctta cagtgcatct cgttattgcg agactgagcg
     6481 atagggaaat tccctataat tgaggtggta ccgcgcatcg acgtcctcac acaagttttt
     6541 tgtgtgagga tttttttgat ggaggttagt atggaaagaa aacgatggcg tcgcttgttt
     6601 agataagtga aatatgttaa aggaaataaa aaggagaaac agaatgaaaa ataaacgttt
     6661 aattggaatt attgctgcat tagcagtctt agtagcagga agcttgattt attcttcaat
     6721 gaataaatca gaagctcaga ataataagga tgagaagaaa ataaccaaga ttggtgtgct
     6781 tcaatttgtg agccatccat cccttgattt gatttataaa gggatccaag atggacttgc
     6841 agaagaagga tataaagatg atcaagttaa aattgatttt atgaactcag aaggtgacca
     6901 aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat ggaaatgacc ttgtggttgg
     6961 tatcgcaaca ccagcagccc aagggttggc tagtgcaaca aaagacctac cggttatcat
     7021 ggccgctatt acagacccaa ttggtgctaa cttggttaaa gatttgaaaa aaccaggtgg
     7081 caacgttaca ggggtatctg accacaatcc agctcaacaa caagttgaac tcatcaaggc
     7141 tctgacaccg aatgtgaaaa caatcggagc tctttactca agtagcgaag acaattcaaa
     7201 aacacaggtc gaagaattta aggcttatgc tgaaaaagca ggtctgacag tggaaacatt
     7261 tgcagttcct tcaacaaatg aaattgcctc aactgtcact gttatgacta gcaaggtaga
     7321 tgctatttgg gttccaattg ataacaccat tgcatcagga tttccaacgg ttgtctctag
     7381 caatcaaagt tctaagaaac caatttatcc cagtgcgaca gctatggtag aagtaggtgg
     7441 tttggcatca gttgtaattg accaacatga ccttggtgtg gcaacaggta aaatgattgt
     7501 gcaagtcttg aaaggtgcaa aaccagccga taccccagtc aatgtctttt caattggtaa
     7561 gtcagtcatc aataaaaaaa tagcacaaga actaggtatt actattcctg agtctgttct
     7621 caaagaagca ggacaagtca tcgaataaat aaggtaggga ggaggagact cttcccattt
     7681 tttaaaaaga tgaatataga aaggattaaa taaaatatga ttgtttccat tatttctcaa
     7741 ggatttgtct gggctattct aggtctggga atctttatga catttaggat tttaaacttt
     7801 ccagatatga cgacagaagg ttccttccct cttgggggag ctgttgctgt cactttgata
     7861 accaaaggcg tgaacccatt tttagcgaca cttgttgctg taggagcagg ttgtttggct
     7921 ggaatggcag caggccttct ttatacaaaa gggaagatcc caaccttgct ctcagggatt
     7981 ttggtgatga cttcttgtca ctcaatcatg ctcttgatta tgggacgtgc gaatttaggc
     8041 ctgcttggaa ccaagcaaat tcaggatgtt ttgccttttg attcggattt gaatcaactc
     8101 ttgacaggtc tcatctttgt gagtattgtt attgctctca tgctcttttt cttggacact
     8161 aaactcggac aagcctatat tgctacaggg gataatcctg atatggctag aagtttcggg
     8221 attcatactg gacgcatgga gctcatgggc ttggtcttat caaatggtgt gattgccctt
     8281 gcaggtgccc tcattgctca gcaagaaggt tatgccgatg tgtctcgagg gatcggggtt
     8341 atcgttgtgg ggcttgcaag tttgattatt ggagaagtta ttttcaagag tttgagcttg
     8401 gcagagcgtt tggttactat cgttgtaggt tctatcgctt atcaattttt agtgtgggca
     8461 gttatcgcac ttggctttaa tacaagttac cttcgtttat acagtgcctt gattttagca
     8521 gtctgcctca tgattccaac atttaagcaa acaatcttga aaggagccaa gttaagcaaa
     8581 tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt taaaaatggc tttgatgaag
     8641 aaaagattat tttaaatgat gtttccttag aaatttttga acaggacttt atcacgattt
     8701 tgggcggaaa tggtgctggt aaatcaaccc tctttaacac tattgcagga accatatcac
     8761 taaccagtgg aactatccgt attttaggtg aggatgttac caagttttca ccagagaagc
     8821 gcgctaagta tctgtctcga gtcttccaag atccaaagat ggggacagct cctcgtatga
     8881 cagtggcaga gaatctcctg attgccaagt ttcgtggtga aaagcgtgga ctatttccga
     8941 gacgtctggc tagctataag gataagtttc aggcgaccat tgaaaaagtg ggaaacggtc
     9001 ttgagaaaca cttgaataca ccgattgagt tcttatcagg tggacaaaga caggctttga
     9061 gtctcttgat ggcaaccttg aagcgacctg aattactctt gttagacgag catactgctg
     9121 ccctggatcc aaagactagt gttgctttga tggaattgac agatgaattt gttaagaaag
     9181 atcaattgac agcccttatg attacccatc atatggaaga tgctctcaaa tatggcaatc
     9241 gcttgattgt catgaaagaa ggacgggtta ttcaagattt aaaccaagaa gaaaaagcaa
     9301 aaatgaaaat ctctgattat tatcaactct ttgaataaag tagggaaaat gagtgaaatg
     9361 gtttactttt tttctgaaat aaagtatact atataaagta aactatgata acatggaggt
     9421 attgtgtatg gttgacaaac aagtcattga agaaatcaaa aacaatgcca acattgtgga
     9481 agtcatagga gatgtgattt ctttacaaaa ggtaggacgg aactatctag ggctctgtcc
     9541 ttttcatggt gaaaaaacac cttctttcaa cgttgtagag gataagcagt tttatcactg
     9601 tttcggttgt ggtcgctcag gtgatgtttt taagttcatc gaggagtacc aaggggttcc
     9661 ctttatagag gcagtccaaa tcttaggtca gcgtgttgga attgaggttg aaaaaccgct
     9721 ttatagtgag cagaagccag cctcacctca ccaagctctt tatgatatgc acgaagatgc
     9781 agccaaattt taccatgcga ttctcatgac aacgactatg ggcgaagagg ccagaaatta
     9841 cctttatcag cgggggttga cagatgaagt gcttaaacat ttttggattg gtttagcacc
     9901 tccagaacga aactatctct atcaacgttt gtctgatcag tatcgtgaag aggatttact
     9961 ggattcaggc ctgttttatc tctcggatgc caatcaattt gtagacacct ttcacaatcg
    10021 cattatgttt cccctgacaa atgaccaagg aaaggtcatt gccttctcag gtcgtatctg
    10081 gcaaaaaacg gattcacaaa cttctaagta taaaaacagc cgatcgactg taatttttaa
    10141 caaaagttac gaattatatc atatggatag ggcaaaaaga tcttctggaa aagctagtga
    10201 gatttacctg atggaaggat tcatggatgt tattgcagcc tatcgggctg gaatcgaaaa
    10261 tgctgtggcg tcgatgggaa cggccttgag tcgagagcat gttgagcatc tgaaaaggtt
    10321 aaccaagaaa ttggttcttg tttacgatgg agataaggct gggcaagccg cgacattgaa
    10381 agcattggat gaaattggtg atatgcctgt gcaaatcgtc agcatgcctg ataacttgga
    10441 tcctgatgaa tatctacaaa aaaatggtcc agaagacttg gcctatctat taacgaaaac
    10501 tcgtattagt ccgattgagt tctacattca tcagtacaaa cctgaaaacg gtgaaaatct
    10561 gcaggctcag attgagtttc ttgaaaaaat agctcccttg attgttcaag aaaagtccat
    10621 cgctgctcaa aacagctata ttcatatttt agctgacagt ctggcgtcct ttgattatac
    10681 ccagattgag cagattgtta atgagagtcg tcaggtgcaa aggcagaatc gcatggaaag
    10741 aatttccaga ccgacgccaa tcaccatgcc tgtcaccaag cagttatcgg ctattatgag
    10801 ggcagaagcc catctactct atcggatgat ggaatcccct cttgttttga acgattaccg
    10861 tttgcgagaa gactttgcat ttgctacacc tgaatttcag gtcttatatg acttgcttgg
    10921 ccagtatgga aatcttcctc cagaagtttt agcagagcag acagaggaag ttgaaagagc
    10981 ttggtaccaa gttttagctc aggatttgcc tgctgagata tcgccgcagg aacttagtga
    11041 agtagagatg actcgaaaca aggctctctt gaatcaggac aatatgagaa tcaaaaagaa
    11101 ggtgcaggaa gctagccatg taggagatac agatacagcc ctagaagaat tggaacgttt
    11161 aatttcccaa aagagaagaa tggagtaata atggcaacaa aacaaaaaga agtaacaaca
    11221 tttgacgtac aggtagcaga atttatccgt aatcataagc aaaaagggac agcaacagat
    11281 gatgaaatca atgcaagtct ggttattcct tttaccttgg acgctgatgg gattgaagat
    11341 ctcttgcaac ggattcagga tgcagggatt tctatcacag ataacgaagg aaatccaagt
    11401 gcgcgtgttc ttagcaatga agaagaacca gaactcagcg atgaggactt gattgggtca
    11461 acttctgcta aggtcaatga ccctgtccgt atgtacttga aagaaatagg ggtcgttcct
    11521 ctcttgacca atgaagagga gaaagagttg gcactggctg ttgaagctgg tgatatcgaa
    11581 gccaaacaac gtcttgcgga agccaatctt cgtttggttg tttccattgc caaacgctat
    11641 gtcggtcgtg gtatgcagtt ccttgacttg attcaagaag gaaatatggg cttgatgaag
    11701 gcggttgaca agtttgacta ttctaaaggg ttcaagtttt caacttatgc aacttggtgg
    11761 attcgtcagg ctatcactcg tgctattgcg gaccaagctc gtaccatccg tatcccagtt
    11821 cacatggttg aaactatcaa taaattggtt cgtgaacagc ggaatctcct tcaagaattg
    11881 gggcaagatc cgacaccaga acagattgct gaacgaatgg atatgacacc tgataaggtt
    11941 cgtgaaatct tgaagattgc ccaagaacca gtatctcttg aaactcctat cggtgaagag
    12001 gacgatagcc accttggaga ctttatcgaa gatgaagtga ttgaaaatcc agtggattat
    12061 acgactcgta tcgtcttgcg tgagcaattg gatgaaatct tagatactct tacagaccgt
    12121 gaagaaaatg ttctgcgtct acgttttgga ctagatgatg gaaaaatgcg cacacttgaa
    12181 gatgtgggga aagtctttaa cgtaactcgt gagcgtatcc gtcagattga agcaaaggct
    12241 ttgagaaaac tacgccaacc aagtcgtagc aaaccgcttc gtgattttat tgaagactaa
    12301 gagtgaggaa aatatggctt atacagaaga gcaaattgaa aacatcaaaa cacggatttt
    12361 aacagccttg gaagaagtca tcgaccctga gttgggaatc gatattgtca atcttggttt
    12421 gatctatgag attcgttttg acggtgacac agggcaaaca gagattgaca tgactttgac
    12481 aactatgggt tgtcccttag cagacctttt gacagaccag atttatgatg ctatgataga
    12541 ggttccagaa gtaacggata ctgaggttaa attagtctgg tatccagcct ggacagttga
    12601 aaaaatgagt cgctatgccc gcattgccct aggcattaag taaacatata aaagcatgtg
    12661 agagactgtt ggaaaagtga ggaaatttcc cctcttttcc tctagtctct cctttctttt
    12721 gctgatttta ttcaaagaaa atgatataat agtagttatg gagaaaaaga aattacgcat
    12781 caatatgttg agttcaagtg agaaagtagc aggacaggga gtttcaggtg cttaccgtga
    12841 attagttcgt cttcttcacc gtgctgccaa ggaccaattg attgttacag aaaatcttcc
    12901 aatcgaggca gatgtgactc actttcatac gattgatttt ccctattatt tatcaacctt
    12961 ccaaaagaaa cgctcaggga gaaagattgg ctatgtgcat ttcttgccag ctacacttga
    13021 gggaagtttg aaaattccat ttttcttaaa gggaattgtg aaacgctatg tattttcttt
    13081 ttacaaccgg atggagcact tggttgtggt caatcctatg tttattgagg atttggtagc
    13141 agctggtatt ccacgtgaaa aagtgaccta tattcctaac tttgtcaaca aggaaaaatg
    13201 gcatcctcta ccacaagaag aggtagttag actgcgcaca gatcttggtc ttagtgacaa
    13261 tcagtttatc gtagtaggtg ctgggcaagt tcagaaacgt aaagggattg atgactttat
    13321 ccgtctggct gaggaattgc ctcagattac ctttatctgg gctggtggct tctcttttgg
    13381 tggtatgaca gatggttatg aacactataa gaaaattatg gaaaatcccc ctaaaaattt
    13441 gatttttcca ggcattgtat cgccagagcg gatgcgcgaa ttgtatgctc tagcggatct
    13501 tttcttgttg cctagttaca atgagctctt tcctatgact attttagaag ctgcgagttg
    13561 tgaggctcct attatgttgc gtgatttaga tctctataag gtgattttgg agggaaatta
    13621 tcgggcgaca gcgggtagag aagagatgaa agaggctatt ttggaatatc aagcaaatcc
    13681 tgctgtctta aaagatctca aagaaaaggc taagaatatt tccagagagt attctgaaga
    13741 gcatctgtta caaatctggt tggactttta tgagaaacaa gccgctttag ggagaaagta
    13801 aaaagtgagg taatctatgc gaattggttt atttacagat acctattttc ctcaggtttc
    13861 tggtgttgcg accagtattc gaaccttgaa aacagaactt gaaaagcagg gacatgctgt
    13921 ttttatcttt acgacgacag ataaggatgt caatcgctac gaagattggc aaattatccg
    13981 cattccaagt gttcctttct ttgcttttaa ggatcgtcgc tttgcctacc gaggttttag
    14041 caaggcactt gaaattgcta aacagtatca gctagatatt atccatactc agacagaatt
    14101 ttctcttggc ctgttgggga tttggattgc gcgtgaattg aaaattccag tcatccatac
    14161 ctatcacacc cagtatgaag actatgtcca ttatattgct aaggggatgt tgatccggcc
    14221 gagtatggtc aagtatctgg ttagaggttt cctgcatgat gtggatgggg ttatttgccc
    14281 tagtgagatt gtccgtgact tgctatctga ttataaggtc aaggttgaaa aacgggtcat
    14341 tcctactggg attgaattag ccaagtttga gcgtccggaa atcaagcagg aaaatttgaa
    14401 agaactgcgt agtaaactag ggattcaaga tggtgaaaag acgttgctta gtctttcgag
    14461 aatctcctat gaaaaaaata ttcaagcagt tttagtagcc tttgctgatg ttctgaaaga
    14521 ggaagacaag gttaaactgg tagtagctgg ggatggccct tatctgaatg acctcaaaga
    14581 gcaagcccag aacctagaga ttcaagactc agtcatcttt acagggatga ttgctcctag
    14641 tgagacggct ctttactata aagcggcgga tttcttcatt tcggcatcga caagcgaaac
    14701 gcaaggtttg acctacttgg aaagcttagc cagtggaaca cctgtcattg ctcacggaaa
    14761 tccttatttg aacaacctca tcagtgataa aatgtttgga gccttgtact atggagaaca
    14821 tgatttggct ggtgctattt tggaagccct gattgcaaca ccagacatga atgagcatac
    14881 cttatcagag aaattgtatg agatttcagc tgagaacttt gggaaacgag tgcatgagtt
    14941 ttatctggat gccattattt caaataactt ccagaaagat ttggctaaag atgatacggt
    15001 cagtcagcgt atctttaaga cagttttgta tcttccgcaa caggtggttg ctgtacctgt
    15061 aaaaggatct agacgcatgt tgaaggcttc aaaaacacag ttgatcagta tgagagacta
    15121 ttggaaagac catgaagaat agaaagagga acagctatga aaaaaacaat taatgagaag
    15181 cggtcgtgat aaaaagattg cgggtgtttg tgctggggtg gcccattatc tggatatgga
    15241 tccgactatc gttcgagtca tttggggtgt tcttacttgc tgttacggag ctggaattgt
    15301 agcttacatt attttatgga ttatcgcacc agtagcaact gactattgaa aactagctca
    15361 attcatgcta agataataga aaatagaatg taacgaagga gagaaaaatg gcatttggag
    15421 ataatggaaa tcgtaaaaaa actatgtttg agaaaataac cttgtttatc gtgattatca
    15481 tgctagtagc aagtttattg ggaatttttg caactgcaat tggtgccctc agtaatctat
    15541 aaaatagatt caagaaaatt tagtgactgg gatttcccag ccctttttta aagtgagaag
    15601 aaataatgag tatgttttta gatacagcta agattaaggt caaggctggt aatggtggcg
    15661 atggtatggt tgcctttcgt cgtgaaaaat atgtccctaa tggaggccct tggggtggtg
    15721 atggtggtcg tggaggcaat gtggtcttcg ttgtagacga aggactacgt accttgatgg
    15781 atttccgcta caatcgtcat ttcaaggctg attctggtga aaaagggatg accaaaggga
    15841 tgcatggtcg tggtgctgag gaccttagag ttcgagtacc acaaggtacg actgttcgtg
    15901 atgcggagac tggcaaggtt ttaacagatt tgattgaaca tgggcaagaa tttatcgttg
    15961 cccacggtgg tcgtggtgga cgtggaaata ttcgtttcgc gacaccaaaa aatcctgcac
    16021 cggaaatctc tgaaaatgga gaaccaggtc aggaacgtga gttacaattg gaactaaaaa
    16081 tcttggcaga tgtcggttta gtaggattcc catctgtagg gaagtcaaca cttttaagtg
    16141 ttattacctc agctaagcct aaaattggtg cctaccactt taccactatt gtaccaaatt
    16201 taggtatggt tcgcacccaa tcaggtgaat cctttgcagt agccgacttg ccaggtttga
    16261 ttgaaggggc tagtcaaggt gttggtttgg gaactcagtt cctccgtcac atcgagcgta
    16321 cacgtgttat ccttcacatc attgatatgt cagctagcga aggccgtgat ccatatgagg
    16381 attacctagc tatcaataaa gagctggagt cttacaatct tcgcctcatg gagcgtccac
    16441 agattattgt aactaataag atggacatgc ctgagagtca ggaaaatctt gaagaattta
    16501 agaaaaaatt ggctgaaaat tatgatgaat ttgaagagtt accagctatc ttcccaattt
    16561 ctggattgac caagcaaggt ctggcaacac ttttagatgc tacagctgaa ttgttagaca
    16621 agacaccaga atttttgctc tacgacgagt ccgatatgga agaagaagtt tactatggat
    16681 ttgacgaaga agaaaaagcc tttgaaatta gtcgtgatga cgatgcgaca tgggtacttt
    16741 ctggtgaaaa actcatgaaa ctctttaata tgaccaactt tgatcgtgat gaatctgtca
    16801 tgaaatttgc ccgtcagctt cgtggtatgg gggttgatga agcccttcgt gcgcgtggag
    16861 ctaaagatgg ggatttggtc cgcattggta aatttgagtt tgaatttgta gactaggaga
    16921 ctggtatggg agataaaccg atatctttcc gagatgcgga tggtaatttt gtttccgccg
    16981 cagacgtttg gaatgaaaag aaattggaag aactatttaa tcgtctcaat ccaaatcgtg
    17041 ccttgagatt ggcacgaact acaaaggaaa atccatctca gtaaagaagc taaaaaatcc
    17101 cggctctttg tcaactgtag tgggttgaag tcagctaagc ttgagaaagg acaaatttcg
    17161 tcctttcttt tttgatgttc agagcgataa aaatccgttt tttgaagttt tcaaagtttc
    17221 gaaaaccaaa ggcattgcgt ttgataagtt tgatgagatt attggtcgct tccagtttgg
    17281 cgttggaata aggtaattga agggcgttga cgattttctc tttgttcttt agaaaggttt
    17341 taaagacagt ctgaaaaata ggatgaacct gcttaagatt gtcctcaata agtccgaaaa
    17401 atttctctgg ttccttatta tagagctgat agtggtgttt caagtcttct gaatagctca
    17461 aaagcttgt
//
LOCUS       DBEJJE010000042        17434 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEJJE010000042 DBEJJE010000000
VERSION     DBEJJE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.42"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1149)
                     /locus_tag="ACL3F5_001553"
     CDS             complement(<1..1149)
                     /locus_tag="ACL3F5_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0515324.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRKNLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNANTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQP"
     gene            complement(1403..3136)
                     /gene="ptsP"
                     /locus_tag="ACL3F5_001554"
     CDS             complement(1403..3136)
                     /gene="ptsP"
                     /locus_tag="ACL3F5_001554"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0515325.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3142..3405)
                     /locus_tag="ACL3F5_001555"
     CDS             complement(3142..3405)
                     /locus_tag="ACL3F5_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0515326.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3756..3974
                     /gene="nrdH"
                     /locus_tag="ACL3F5_001556"
     CDS             3756..3974
                     /gene="nrdH"
                     /locus_tag="ACL3F5_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0515327.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSSAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4055..6214
                     /gene="nrdE"
                     /locus_tag="ACL3F5_001557"
     CDS             4055..6214
                     /gene="nrdE"
                     /locus_tag="ACL3F5_001557"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0515328.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6402..7364
                     /gene="nrdF"
                     /locus_tag="ACL3F5_001558"
     CDS             6402..7364
                     /gene="nrdF"
                     /locus_tag="ACL3F5_001558"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0515329.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            7546..8307
                     /locus_tag="ACL3F5_001559"
     CDS             7546..8307
                     /locus_tag="ACL3F5_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0515330.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(8586..8843)
                     /locus_tag="ACL3F5_001560"
     CDS             complement(8586..8843)
                     /locus_tag="ACL3F5_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0515331.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8886..10292)
                     /gene="lacG"
                     /locus_tag="ACL3F5_001561"
     CDS             complement(8886..10292)
                     /gene="lacG"
                     /locus_tag="ACL3F5_001561"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0515332.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(10507..12198)
                     /locus_tag="ACL3F5_001562"
     CDS             complement(10507..12198)
                     /locus_tag="ACL3F5_001562"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0515333.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(12198..12515)
                     /locus_tag="ACL3F5_001563"
     CDS             complement(12198..12515)
                     /locus_tag="ACL3F5_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0515334.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(12551..13387)
                     /locus_tag="ACL3F5_001564"
     CDS             complement(12551..13387)
                     /locus_tag="ACL3F5_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0515335.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(13621..14601)
                     /gene="lacD"
                     /locus_tag="ACL3F5_001565"
     CDS             complement(13621..14601)
                     /gene="lacD"
                     /locus_tag="ACL3F5_001565"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0515336.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(14603..15532)
                     /locus_tag="ACL3F5_001566"
     CDS             complement(14603..15532)
                     /locus_tag="ACL3F5_001566"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0515337.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKEFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(15543..16058)
                     /gene="lacB"
                     /locus_tag="ACL3F5_001567"
     CDS             complement(15543..16058)
                     /gene="lacB"
                     /locus_tag="ACL3F5_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0515338.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(16089..16514)
                     /gene="lacA"
                     /locus_tag="ACL3F5_001568"
     CDS             complement(16089..16514)
                     /gene="lacA"
                     /locus_tag="ACL3F5_001568"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0515339.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(16671..17168)
                     /locus_tag="ACL3F5_001569"
                     /pseudo
     CDS             complement(16671..17168)
                     /locus_tag="ACL3F5_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            complement(17184..>17434)
                     /locus_tag="ACL3F5_001570"
     CDS             complement(17184..>17434)
                     /locus_tag="ACL3F5_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515340.1"
                     /translation="YQGLMKIYPQAQTSRKSSKLKPLTVKDKAYNHALSKERSKVESI
                     LAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         5189 a         3601 c         3191 g         5453 t
ORIGIN      
        1 aggttgcgga cttggactag gttctggagt cggttgtgga cttggttgtt ctggtcttga
       61 atctggtacc caatggtttg aacgataacg aaggggaatt atacgagcaa ttcgttcttc
      121 caattcagac atttgttcat aagggataaa gtggtaatgg ttaccatgag ggacagctac
      181 acctctggcg gttcgacttg tgatttgcgc tgggtcgaaa ataaggccat cagattctac
      241 atggcgttga ctcaaaggca gtttgtagag ctgtttcaag agactatcaa tgtcattact
      301 ttgacttgct tgactgttag tgttgctgtt gttgcttgtg ttagcatttg tagttcctgg
      361 attgcttaca gaaggtaccc agtttgttct tggagtgtta tcgctatttt gtcggcgata
      421 ggttcttaaa tttgacagat ttttccgacc agataggaag gcttctgcag cagccaactc
      481 gctagctgat aactcattct taggaatgta atggtaatga tctccatgag gaacgatata
      541 agcatcacca gtatcctcta tgatatcaga agcattaaag atataaccat catctgtggt
      601 gtagcgtccc tgtgaacgtg caaaggctac cgcaccatcg tttgctgaag tccctccttc
      661 acgatgctga ctatgttctt gtttttgccg attgatttct tcttttgtac ggacattatc
      721 cgcgtgggca gcatccttaa ggtaaacata gtattttcca tctaccttaa tcacataacc
      781 acccttgatt tcactgataa tatcctcgtc ctttagctgg tagtttggat ccttcatcag
      841 caattcttca ctgatgatag cgtcataagg aaccttacca ttgtaataat gatagtggtc
      901 gccatgtgaa gtgacatagc cttggtctgt tatcttgatg acgatttgct cagcattgat
      961 tccttcacgc ttgctaacct catcaggagt caaattctcc gttttttgcg tcgcttgttt
     1021 tccatctata taggaaacac gattattttc cttaaccgtt ctagcttgat acagtcccaa
     1081 ctcgtaagaa caaacactta aaatcaaagc tgccgcagaa ccaacaaggt atttcttatt
     1141 aattttcatc gaaactctct ttctatttga tatttctagt tgcaattcat ttctaaattg
     1201 cagaaactcc cctctattac ttaactggtt aatagtttac tcctaaatct ccaacttgtc
     1261 aagaatttta tgaaccattt aagtattttt tgttctgacc actacttttt caaggttgga
     1321 ctttctataa gaaagatttt cttgaaaatt ctttttaaaa tatcaaaaaa atccctgtaa
     1381 ctgagttgca gggacttttc gattaatcaa aattaacgta ttctttttga agttcaagaa
     1441 cttcttccat tgttgagcat tctgtaaggg cacggtttgc gtactcttcc atcttagctg
     1501 tgtcgagttt cttcatcaag ctgcgtgtac gaagtacaga tgttgctgac atagagaact
     1561 catccaagcc cattccgaca agaagtggaa cagcttgttg gtcaccagcc atctcaccac
     1621 acataccagc ccatttacct tcagcgtgag ctgctttgat cacattgtta atcaagcgta
     1681 ggattgatgg attgtatggt tggtaaaggt atgaaacttg ttcgttcata cggtctgctg
     1741 ccattgtata ttggatcaag tcgtttgtac caattgagaa gaagtcaact tctttagcaa
     1801 attggtctgc aagcatagcc gctgcaggaa tctcgatcat gataccaact tgaatgttat
     1861 ccgcaactgc aacaccttca gcaagaaggt ttgctttttc ttcatcaaag actgctttcg
     1921 ctgcacggaa ttctttcaag agcgcaacca ttgggaacat gatacgcaat tgaccgtgaa
     1981 cagacgcacg aagaagagca cggatttgtg tgcggaacat agcatctcca gtctcagaga
     2041 tagagatacg aagagcacgg aatccaagga atgggttcat ttcgtgaggc atatcgaagt
     2101 aaggaagttc cttatctcca ccgatatcca ttgtacgaac gacaacaggt ttaccgttca
     2161 ttccttcaag aacagccttg tatgcttcat actgctcatc ttcagttggg aagtcttgag
     2221 aatccatgta caagaactct gtacggtaaa gtccaacagc ttctgcaccg ttgttgttaa
     2281 caccttcaac gtcttttgga gtaccaatat tggcagccaa ctcgaagtgt ttaccgtcag
     2341 cagtcactgt ttgagcatct ttcaaaagtg cccattcagc tttttgtttc gcataggctt
     2401 caccagctgc tttaaattct gccgcttgtt catctgttgg gttgataatc acttctccag
     2461 tgatcccgtt aacagcaagg atgtcaccgt ctttaacgat ttcagtgatg ttgtttgtac
     2521 ctaatacagc agcaatttca agtgtacgtg ccatgatagc tgagtggctt gtacgtccac
     2581 caatgttggt tacaaaagct tttacaaagt ttttgtccaa ttgagctgta tctgaaggag
     2641 tcaagtcatg cgcaatcaca atcacttctt cattgataga agctgggttt ggcaattttt
     2701 taccaagaag gtttgccaat acacgttttg tcacgtcgcg gatatccgct gcgcgttctt
     2761 gcatgtatgg gttgtcttcc atgccttcaa agatagtgat aaacatatct gtaacttctt
     2821 tcagacctgc ttctgcattc actttcttcg cacggatagt ttccttgatt tggctgatca
     2881 tttctgggtc agcaagaacc attaagtgag catcaaaaac ttgagctgct tcttcaccga
     2941 gcgtacctac tgctttctcg cgaataacag aaagctcgtc ttgtgatgcc tgtagagcgg
     3001 catcaaggcg agcttcttct gcgtttgtat cttcgactgt aatagtctca aatgacaaat
     3061 ccggctgaac gagtagatat gcttttgcaa ctgcaacacc gtcagatgct gcgattcctt
     3121 taagcatttc tgtcatttcc cttatgccaa tccttctttt tccattgttt ctgagattgc
     3181 agcgatagcg tcatctgcat ctgcaccttc agctgagata gttacgtcag caccttgacc
     3241 aacaccaaga ctcataacac ccataattga tttaaggtta actgatttac ctttgtactc
     3301 aagagtgata tctgaagcaa atttgctagc agtttgtacc aacaatgttg ctggacgtgc
     3361 gtgaatacct gtttctgcca ctacgtggaa atctttagaa gccatagttt gactctcctt
     3421 ttgttctttc tttttttgag ttatatgtga taacccttac aatttagtat tataccatct
     3481 tctaggattt ttttcaagca ttttctggat tttccttcaa tttcctttca gataacttgc
     3541 tgaaaatctt ctatcctaga taacaaaaca caggatatag tttcttcaaa aacaatttat
     3601 aggataatca ttgctatttc acaatacaaa cactatatat tgtgtttata tataaaaaca
     3661 acaaaagaac accactatat ttagtttaaa tcattgacaa aattttattt tctgatatac
     3721 taagatagta ttaaattttg aagaggagtt acacaatggt aaccgtttat tctaaaaaca
     3781 attgtgtcca atgtaaaatg accaagcgtt tcttggacag taataatgtc tcttatcgtg
     3841 aaatcaatct tgatgagcaa cctgagtacg tcgatcaagt taaagagctc ggttttagct
     3901 cagctcctgt tatccaaaca ccaactgaag tcttttcagg tttccaacca ggaaaactga
     3961 aacaattagc ataatcttag tacatcatcc agaagaaact gctttcaggg ctaacttaga
     4021 agcctttctt ttgtaattag ataagggaaa ttttatggga ttaaaacatc ttgaagacgt
     4081 gacttacttc cgtcttaata acgaaattaa ccgtcctgtt aatggacaaa tcatgcttca
     4141 taaagataag gaagccttgg atgctttctt taaagaaaat gtagttccaa acactatggt
     4201 ttttgattca atcaaagaca aaatcaatta cctcattgaa cacaactaca tcgaaacagc
     4261 ctttatcaag aaataccgtc cagagttctt ggaagaattg gctcaattta tcaaagacca
     4321 aaacttccaa ttcaagtcat tcatggcagc ttataaattt tacaatcaat atgccttaaa
     4381 gactaatgac ggtgaatact atcttgaaaa tatggaagac cgtgtcttct tcaacgccct
     4441 ttatttcgct gatgggaatg aagctgttgc aatcgatatt gccaatgaaa tcatccacca
     4501 acgctaccaa cctgctactc cttccttctt gaatgctgga cgtgctcgcc gtggggagtt
     4561 ggtatcttgt ttcctaatcc aagtgacgga tgatatgaac tctatcggac gttctatcaa
     4621 ctcagctctt caactttcac gtattggtgg tggtgtggga attaccctca gcaaccttcg
     4681 tgaagctggt gcacctatca aaggctatga aggagctgct tcaggtgtcg ttcctgttat
     4741 gaagcttttt gaagacagct tctcttactc caaccaattg gggcaacgtc aaggtgccgg
     4801 tgttgtctac ctcaacgtct ttcacccaga tatcatcgct ttcctttcaa ctaagaaaga
     4861 aaacgctgat gaaaaagtac gtgtcaagac tctatcactt ggtgttgtag tacctgataa
     4921 attctacgaa ttggctcgta aaaatgaaga aatgtacctc ttcagccctt actctgtaga
     4981 aaaagaatac ggtgtgccat tcaattacat cgacattact gaaaaatacg atgaattggt
     5041 cgcaaatccc aatattcgca agacaaaaat caaggcgcgg gatttggaaa ctgaaatctc
     5101 taaattgcaa caagagtctg gctatcctta tgtagtcaac atcgatacgg ctaaccgtgc
     5161 aaatcctgtt gatggaaaga ttatcatgag taacttgtgt tctgagattc ttcaagttca
     5221 agaaccaagc ttgatcaacg atgctcaaga attccttcaa atgggaacag atgtttcatg
     5281 taacctgggt tcaaccaacg tggttaacat gatgacttca cctgattttg gtcgttctat
     5341 ccgtgctatg gttcgtgccc ttactttcgt tacagatagt tcacatatcg tagctgtacc
     5401 aacgattgac catggaaata gccaagccca cacttttggt ctcggtgcca tgggactgca
     5461 cagctacctt gcccaacaac tcattgaata tggttcacct gagtctgttg aatttacaag
     5521 catctacttt atgcttatga actactggac cttggtagag tcaaacaata ttgcgcgtga
     5581 acgtggtatt accttccaca actttgaaaa atcagactat gctaacggaa gttactttga
     5641 caagtatgta actggtgaat ttgttccaac atcagaccgt gttaaagaac tcttcaaaaa
     5701 tgtttttatc cctggtgttg ctgattgggc tgaacttcgc gacaaggttc aagaagatgg
     5761 tctttaccac caaaatcgcc ttgctgtagc gccaaatggt tctatcagct atatcaacga
     5821 cgtttctgct tctatccacc cgattacgca acgtatcgaa gaacgccaag agaagaaaat
     5881 tggtaaaatc tactaccctg ctgctggctt gtctacagaa accattcctt actacacttc
     5941 tgcctacgat atggatatgc gtaaagtcat cgatgtttac gctgctgcga ctgaacacgt
     6001 ggatcaagga ctttcactca ccctcttcat gcgcagtgac attccaaaag gcctttacga
     6061 atggaagagg gaaaataaac aaacgacacg tgatttgtcc atccttcgta actatgcctt
     6121 taacaaggga atcaagtcta tctactacgt ccgtaccttt acagatgacg gtggagaagt
     6181 cggcgccaac caatgtgaaa gctgtgtgat ttagtttcta gcatagaaac actatttttc
     6241 cctaagcagc actgataaaa tcaaatctac tatgtcataa cataatttat gtaacatttt
     6301 aaaagtcggg cttccgactt tttgtgcgat actcctatag aattatggta aagtagaaat
     6361 aattgtgagt tcgcaatact aaacacagaa agagatttta aatggaaact tactacaaag
     6421 ccattaactg gaatgccatc gaagatgtca tcgacaaatc aacttgggaa aaactgacgg
     6481 agcaattttg gctcgataca cgtattccct tatcaaacga cttggatgac tggagaaagc
     6541 tatctaacaa agagaaagac ttggtcggaa aagtttttgg tggtttaacc cttcttgaca
     6601 ctatgcaatc tgaaactggg gttcaagccc ttcgcgcaga catccgtaca ccacatgagg
     6661 aagctgtttt caataacatc caatttatgg aatctgtcca cgctaaatct tactcatcaa
     6721 tcttttctac cttgaatact aaggctgaga ttgaagaaat tttcgaatgg accaatacca
     6781 atccttacct acaaaagaag gctgagattg tcaacgaaat ctacctaaac ggcagcccac
     6841 ttgaaaagaa agttgccagc gtcttcctcg aaaccttcct cttctactct ggtttcttca
     6901 ctcccctcta ctatctcggt aacaacaaac ttgccaacgt tgcagaaatc attaaattga
     6961 ttattcgtga cgagtctgtt cacggaacct acattggtta caaattccaa cttggtttca
     7021 atgaattgcc tgaagaagag caagaaaaac tcaaagaatg gatgtacgac ctactctata
     7081 ctctttatga aaatgaagaa ggctacacag agagtcttta tgacggtgtt ggttggactg
     7141 aagaggttaa aaccttcctt cgctacaatg ccaataaagc tctcatgaac atgggacaag
     7201 atccactttt cccagattca gctgaagatg tcaacccaat cgttatgaac ggtatttcaa
     7261 caggaacttc caaccatgac ttcttctctc aagtcggaaa tggttacctt cttggcgaag
     7321 ttgaagccat gcaagacgat gactataact acggtttaga ctaattctcc atcactctca
     7381 atcatcaaaa agtaaactag aaacatcaaa gttataaccc aacaaaaata tcgaaagttt
     7441 tgaaaacaaa cttcgatatt tttgtttttg tttcattttg ttgtttttgt atttgaatga
     7501 tgagtttgtt tatggtaaga tagtagtagg aaacgaggtg ataatatgct caaacaagaa
     7561 aaattaacca aaattttaga gatagtaaat agcaaaggaa ccataacagt taaacagatt
     7621 atggacgaaa tagccgtttc agatatgact gcaaggcgct atttacagga attagctgat
     7681 aaagatttgc tgattcgtgt gcatggtgga gctgaaaaac ttcgaaccaa ctcccttttg
     7741 actaatgagc gatcaaatat tgaaaaacaa gccctccaaa cggcagaaaa acaagaaata
     7801 gcccattttg caggcagtct agtagaagaa agagaaacta ttttcattgg accaggaaca
     7861 acattagagt tttttgcgcg tgagttgcct attgacaata tccgcgtcgt aaccaacagt
     7921 ctacctgttt ttctgatttt aagcgaacga aaattaacag atttgatttt gataggtgga
     7981 aattatcgcg atattacagg tgcttttgtt ggcacattga ccctacaaaa tctctctaat
     8041 ctccaatttt ctaaagcttt cgttagctgt aatggtattc aaaacggagc tctagctact
     8101 tttagcgagg aagagggaga ggctcaacgc atcgctttaa ataattctaa taaaaaatat
     8161 ttactcgcag atcatagtaa gttcaataag tttgattttt atacttttta taatatatca
     8221 aatcttgata ctattgtttc agattctaaa ctaagtgatt caatcctttt taagctatct
     8281 aaacacatta aagtcatcaa gccttaataa actgaaagag cctgggtaac aactcaattt
     8341 cagaagaaaa aaagtaaatc ttcccacaat aaaaagcata gtatcaggtg ttgaaacacc
     8401 tgatactatg cttttttcta tatcaaagac tttttgccca attcctcaaa gctatacatt
     8461 gagaaatctg cgactcgctt cctagtttaa agttgctctt tgattttcat tgagtataag
     8521 caacgtgatt agataagagt tttacagagt actaaatata agatttaact tttttgagaa
     8581 attggttacg attgttgaaa cggcataaaa tctgaatcaa aggagatagt atcccattct
     8641 tcaggattga taaaatttaa aaatagattt ttaaattctt ccagatcatc atctgaatga
     8701 caaatccatt ctttaccagt cgagacatac cattttccaa gacttttcaa ttcttcactc
     8761 gtcaaacacg gtatttgaga gcatttttcg aaatttataa tataaacttt ttcataaata
     8821 gattggataa aatctttgaa catctttttg actcactaaa attctatatc taatgactaa
     8881 ttctactagt ctataatctg agtttccgct actttcttgt accagtgagc tgatttctta
     8941 ggataacgtt cttgagtttc aaaatctaca tagaagagac cataacgttt ctcataaccg
     9001 tttgaccatg agaagacatc cattaatgac caaatgaagt aaccttttac attagctcca
     9061 tctgcaatcg catcagacaa gatctccaag tgttgtttca cgtaatcaat acgaccatca
     9121 tcgtaaacag tgttattaac gaactcatct ttatagccga gaccattttc agtgatataa
     9181 attttcttgt agttaggata atctttcttc acacgcatga tttggtcata caaaccttga
     9241 gggtagataa tccaatccca atccgtgcgt gatacatagt caggagctac acgacgacca
     9301 atacctttga tttgatactt agagcttcct ttttcacctt taccattatg gataatttca
     9361 gtttctccat caaaggcttc catccagtca ctcatatagt agttgattcc taggaaatca
     9421 ttcaagtctt ttgcagcttc taatgctgta aaatcttctt cacgaagatc caaactacca
     9481 ccattgactg ataagatatg gttgacacct tccatggttt cagctgaata gcgacctaga
     9541 taagttgcgt ctaagatgaa tttattgtgg atgatatctt ccaactctgc tgcacgaaca
     9601 tctgctggat tttcaggatc tagaggatat ttagtaggca gggcgtgaac aacaccaatt
     9661 tcccctttat agcctttctc tttgtacaat tttaccgcgc atgcatgaga caccatcata
     9721 ttgtggtgtg attgaaagac tttggcaagg tcgtactgga tacctggagg gaatttccca
     9781 accaaatatt gaccatcacc gattggtcca atttcattaa aggttgtcca atagtttact
     9841 tctggaaatt cttcaaaaca gaaggcagcg tagtctacaa aatgttcgat attttcacgg
     9901 tttaagaagt ctccatttga gtggagagct tctggcgtgt caaagtgatg aagagttaca
     9961 aagggctcaa catgacgttt gtgacactct gcaaataaat tatgataaaa ctcaacacct
    10021 ttagcattta cttgaccata accagtcggg aaaatacgtg accaggcaat agaaattcga
    10081 atgccattga caccatactc ttctgctagc ttgaggtcaa ctggatatcg attgtaaaaa
    10141 tcactggctg gttctgcagt gtaccagtag ttatcttcaa gatatttatc ccacgctact
    10201 ggtcctttac catcagtatg tgtagcacct tctgcttgat aggcagctgt tgcgccacca
    10261 aaaataaagt cttttggaag tgtttttgtc atttttttca cctatttctt gatttaaata
    10321 aagtaaaagt gagaggagag gagtcagtga gccatccttc tccatctcac ttcttgtacc
    10381 aagtcaccga attgtgacat gaggaggtaa aaacgatatc tttttaccga cgaattaata
    10441 aggcgattag gaaattcgcc atagcgattt ccgtaacgat gggagactgt ttcacagttc
    10501 ctagccttaa tcgaattgct cttgtacgaa tgctagggca ccttttccat cacgagttaa
    10561 tttgatgtat tgagcgcctt ctgtcttagc aagtttaata ccgagcttat ctgtttctgc
    10621 cttcatatct tcaaagtttg aagcaacttg aggagcaagg ataaccaaat caaactctgg
    10681 caacatttca cggtgagcac catagccacc tgctgctgct ttcacaggga cattgtattc
    10741 tgctgctgcc ttgtttagag catttgcaag gagaccactt gttcctccac ctgcacagag
    10801 aacgaggaca tttgtttctt cagtgatggt attttgtgct gcatcgacac ccgctttttc
    10861 aagaatagca tccgcttttg cagtgttgaa gtttgcagca actttttctt tcaattcatc
    10921 attagactta cctgaacgtt cttcttcaag aatttgttcg tcataaactt taaggaatgg
    10981 atagtaaatg acaacgtcaa ccacgattag aagagcagca agaatgaatg atagaacttg
    11041 gaagttcgta ccaagaacta gacctagtgg agctggggtt gtccatggta gattagcagt
    11101 aaatgaattc attccaagtg tttcaataaa gaatttgaaa atccatacgt ttgcgatagg
    11161 agcaaaaata aatggaatga agaagattgg atttaataca agtggtgcac caaacaagat
    11221 tggttcattt acaccgaaga aggtaggaac tactgaagca cgtccgattg cacggttacg
    11281 ttttgatttt gttaaccaca taaacatgaa tggaacaacc agtgtcgcac cagtaccacc
    11341 catggtaacg ataaacattt gtgtaccaga agtaagaatc ttgtcagcgt gcataccttg
    11401 ttggagaagg ttcaagttga cttcagcatt tgcataggta atagctgcga tagcaggttc
    11461 aacgatagat ggaccatgaa taccaacaaa ccagaagaag gcaaaggcac caaagataat
    11521 ggtgatacct agataaccat cagcagcaga gaataatggt gcgaagaatt taccgattga
    11581 ttcagctacg cttgcaccga caaaatgacg agctagtaaa tcaagagcat aaagagaaac
    11641 cactgataga gtgaatggaa tcacatcttt aaagacttgt gagatatttg gtggaacttc
    11701 gtcaggcata cgaatagtga cgttgttctt aacacagacc ttatagatgg ctacagtaac
    11761 gaaggcagca aggaaggctg aaagcaaacc ttttgtcccc aagaatccag tagctagacc
    11821 actttcgata ggatcagctg ccaacatcaa caaaccaaca attgctgcca acaatgttga
    11881 catatagttg atttgattgg ttttttccat gctccggttt actgagtcag tcaatgactt
    11941 agctgttgta ccagctacca agagagccag aatacccata gaatagctat aaggtttcat
    12001 cagaaaggct acaacttcat cagaccattt aaagccccat gagtttggta caaaggcaat
    12061 caagataaag atacttgaga agagaataac aggcatacct gcaatgaaac catcacgaat
    12121 agcacgaaga tagatattac gagatagttt ttcaaagaaa ggctttcctt tctcgataaa
    12181 tgcaattagt ttattcatta tttaactcct ctcttgtaga gttcaattaa atggtgcatt
    12241 aggtctttta acaagatagt tgtcatcaag tgatcttgac catgcatcat ggtcacacta
    12301 tacgctaagt cctcaccaga agcttcctta gtcaatagac ttgtttgcgc gtggtgagcc
    12361 tctgcaatac agctaccagc ttcctctacc agagcgtccg ctttttcaaa atcaccagct
    12421 tcagcagcct tcaaggcttc caatagtttt gaacgagcat cgccagcata ggctacgatt
    12481 tcaaaaccta acaatgttac ttcttctcta ttcatgatag aattctcctt atatagtttt
    12541 aaataaattt ttatgacaat aaacgttgga tatgtagaac tagataaact cgttcacttt
    12601 tatacaaatc aagacccgta tgttgcgtaa tcacatcata gatcttggaa ccaatctcga
    12661 aggcttttgg ataggattgt ttaatatgat cttccatatc cagaagtgat tggttatcat
    12721 ctctagatct gtctaaataa tccaagaaat aattcaaatg gatcataaag cgatcataga
    12781 aatggttatt ctttttagtt cgttgaattg catagtccgt taaaacttct tcaacattcc
    12841 tgagaatttc tttcctctta tcaatcgact ccacaagttc cacttcattt tcaccttcag
    12901 cattaatgaa atgataagca atccgaataa tttcgtcctc aggaaaatga tctgctagct
    12961 tctgacggta aatttcaaaa gcttcatttg cgatttgaaa agcgacagga tacttagcgg
    13021 aaatatctgg cagattacta tccttgtacc ttccttgagt tagagcttga taagaacagt
    13081 aaatatgatc tgtcaaggtt acatagagat actcttgaat cggataatga tatttctttg
    13141 atagcttatc aatgatttca taggtcactg tgataaaatc aagcggaaca tctttgagaa
    13201 gagccataaa gttttctctg gactcttcgg tcttcatccg aaagattttc tcaacctgat
    13261 tttcagcaat caaatccccc ttcttctttc cgaatgcaat ccccttacca attacaatca
    13321 cctcttctcc cttatcattt ctgacaagcg agacattgtg attcattgga tttagaattc
    13381 gatacatgtc aacctccttt tatattttaa aggtatatga gtacaaaaaa tgaccacaaa
    13441 tgaactagaa aatcagctga tttctaattc acctgtgatc atgcctaata ttacttagta
    13501 acactcacct tgtattaact tgtgatttaa gtatagcaca agtaagttat tttgtaaacc
    13561 tttacataca acttttttta aattttttta gattcatgtt cctaaactag gaggactttc
    13621 ttacacacgt tctttccatg aagtcgctgt tgtttgaaga actttattga gctcatcaat
    13681 gttttcaaat ccagttgtgc gaagccattc gcgagctgct gcttcaccat ctttgatgta
    13741 agcttcaact gaccctgccc atgtagcacg gccacaaaga actccgttaa agtttgcacc
    13801 tgattcatga gcaaatacaa gagtatcttg gaagagttta gctgatacac cagcactcaa
    13861 gtagatgtat ggcaagttcg ttgcttcatc ttgcgctttg aagaaggctg ctgcttcttc
    13921 acgtgtataa actacttcac cttcagcgaa gccttcaaca tatttaatgt taacaggaac
    13981 ttcaactttc aagacatcaa tgttaaagcg tgggtctgaa aagactttca tagcgccgat
    14041 aactttgtgt ggttttactt tcgcgtattc tacagaacct gcatccgcaa ttttttcatc
    14101 gtaagcaagg atttcaagga agaatgggat atcttcagcc acacactcag aaccgatgcg
    14161 ttcgatgtag gcttgttttt cttgattgag ttcgtctgag ctatctacat catagtaaag
    14221 caagaattta actgcatctg caccttcttc tttaatacgt tttgcagacc aaacatccaa
    14281 gcagtctggc aagcgttttg tgcttgttgt gtcataacct gttttttcat aagcaaggag
    14341 aagaccagct ttttcatcaa gagctttagt tgctggaagt ccatactcag ggtcaagaag
    14401 catagatgaa gcgtatttag tcaattcatc tgctaccaag actttaagtt cttccatttg
    14461 ggccacagtt ggttcttctg tttggtgttg agccatgagg cgtttcaaag caccacgttg
    14521 gtcaaatgca agagctgaga tgataccatt ttcatcagaa agtttttcta agcgtacacg
    14581 tttttgttct gttaaagcca ttttatacct cttttactat taattgatca tatagagctt
    14641 gatagttggc catgttgaca tgaccagtca ttttttcttg agcattgagc ataccaagga
    14701 catttgcctt gatgagtaat tctgcatccg attctttgtg aagaagtcct gaagaaattc
    14761 ctgccacagt agagtctcca gatccaacag gatttaccac ctgaattcta ggaatatcta
    14821 ccttgtagaa agtgtcacca tgtttggcaa aagtaccgtt ggcaccaagt gaaacgataa
    14881 tccattcaat ccctgcaaac aaaggttctt gaagtacttc ttttaattca tccaaatcct
    14941 cagaaacttc tcttccaaga agctgagaca attcttcatt atttggtttg atgactgttg
    15001 gtttatgggg tgattcaaga acagcctgaa gtgctgcacc tgagcagtcc aagactacag
    15061 gcttgccagc ttgattagca agttctacca agctcgcata gtaatcaact ggaaggccag
    15121 ctggcagact acctgagatg gccactactt caactgactc caagagtttt ttgaaatgtt
    15181 ccaaaaagtc ttgaccttcc tgttccaata cttcaggacc tttttcaaga acttctgttt
    15241 ggttgtctcc gtggagaata gcgatacagt tacgagtttc tccctgaatt gagaagaact
    15301 ctttctttac ttgattatcg atatgttcaa ccaaaaactc accaagtttg ccacccacta
    15361 aaccagtagc aagaacagaa tcgccaaatt ctgaaagtac tcgggtaaca ttgagtccct
    15421 taccaccagc cgttttggtt acatccacca cacgattgac agtatcaatc ttcaactcat
    15481 ccaagggata ggaaatatca atggatgggt tcattgtgac tgttaaaatc ataggtcacc
    15541 tcttagtcgt ggtattctcc gcgatcccat ttttcaagga attctgtaaa gaagtttgcg
    15601 tctgtttgtt gagcattgtg actttcaagg tgttcaattt tcgcaatcaa tttcttgttt
    15661 tcttcagatg gtttgtattc agcatgaatg aaagcttcga tgatatcaca cataagcaat
    15721 tcaccagtaa tcttaccacc aaagccgata acgttagcgt tcaattgttc tttagcataa
    15781 agggctgttg tcatatcacg aaccaaggca gaacgaacac ctggaacttt atttacagcg
    15841 ttgttgatac caacaccagt accacagata cataccccaa gatcagcttg accgctagtt
    15901 acagcttccc ctactttttt accaaagatt gggtagtgag tccgtgtatg gtcatatgta
    15961 ccaaagtcaa tgacttcata tccttttgat ttcaaaaatt ctgaaaccgc cattttttca
    16021 tctgttacga tgtggtcgca tccaattgca attctcattt ttaacttacc tttcttactg
    16081 taatctaatt agcccatttt gttcaacatg tcgacccgga tttgatgacg tccaccatcg
    16141 tatttaccgt taacaaatcc tttagcgatg tttttagcca attcatcacc aacaagttgt
    16201 gcacccatag tgatcatacg tgagttgttg tggccacgag tcatataagc tgaacgttcg
    16261 tcagatactt ctgcagcaac cattcctttg atcttagttg caaccataaa tggaccagct
    16321 ccataagcat caatcacgat accaaggttt tgttcttctt tgtttacttc tgcagcaaca
    16381 gcgagagtca catcaacaaa gtcttgacct tcagctgtaa catccacaag gtggaagttt
    16441 tctttttcta agaagtcttt cacaacttct ttcaatctca aacctgcagc atctgcaccg
    16501 ataacaatag acatattgta tactcctttt tattttttct atgctggatt ccagcagtgt
    16561 attggctgtc tttaaaaaac agtcaattag tcctcacaaa cataatatac tactattgtt
    16621 tgaagaagtc aacagtttgt gtttgttttt gttatttatt ttttactttt ttataaaact
    16681 tctatctcaa accctaattc ttcaacctga ttggcttcta agagacaaac attcttctta
    16741 tcttctaaat gatctccttc ttcaaggaat gttgacaagc cagaccatgg ttcaaaggta
    16801 atgaaagatc ccttgttcaa agttgaccag atgatgaggt ttggaaattc tgcaaaatgc
    16861 actttcaatc ccttatcatg tttaagagaa cgaagggcaa ttgttcgaga ttgcaattca
    16921 tccaaagtca ctgcatctgt gctgaaaaga tcataactaa gatctatttc tttttgtccc
    16981 tctagccatg gacttctatc ttggaaatcc aacatacctg tttctgggaa aggacgtgga
    17041 acagagcaaa tctcttcttt ctcaaactct agataataat cttcatagac ttcatcatca
    17101 agtagaagac aattaaatcc tggatgtcca ccaataaagt aaggcctgac cttactagtt
    17161 tctttattag acttcctgca aaactagaat cctagttcat gattgataat gccagcaatc
    17221 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta
    17281 aacgttttta ctttggcaag gatgctctca accttgcttc tctccttaga taacgcatgg
    17341 ttataggctt tatctttaac tgttagcggt ttgagtttgc tggatttacg tgaagtttgt
    17401 gcttgaggat atatcttcat gagcccttga taat
//
LOCUS       DBEJJE010000043        17046 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEJJE010000043 DBEJJE010000000
VERSION     DBEJJE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.43"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(81..311)
                     /locus_tag="ACL3F5_001571"
     CDS             complement(81..311)
                     /locus_tag="ACL3F5_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515341.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(329..970)
                     /locus_tag="ACL3F5_001572"
     CDS             complement(329..970)
                     /locus_tag="ACL3F5_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0515342.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTFSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(982..1716)
                     /locus_tag="ACL3F5_001573"
     CDS             complement(982..1716)
                     /locus_tag="ACL3F5_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0515343.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMLLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1767..1916)
                     /locus_tag="ACL3F5_001574"
     CDS             complement(1767..1916)
                     /locus_tag="ACL3F5_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515344.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVI"
     gene            complement(1916..2122)
                     /locus_tag="ACL3F5_001575"
     CDS             complement(1916..2122)
                     /locus_tag="ACL3F5_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0515345.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2132..2596)
                     /locus_tag="ACL3F5_001576"
     CDS             complement(2132..2596)
                     /locus_tag="ACL3F5_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515346.1"
                     /translation="MIDKVVRNLLLTFLFCKMTKIINFLTTILVKKKKMCYNVSKLRE
                     KKKGAMMWVLGFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGKK
                     PIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2596..2724)
                     /locus_tag="ACL3F5_001577"
     CDS             complement(2596..2724)
                     /locus_tag="ACL3F5_001577"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515347.1"
                     /translation="MDRTDEVSSKHGFEVVDETDEVSNHTYGKVKLTWFEEIFEEY"
     gene            complement(2784..4073)
                     /gene="hisS"
                     /locus_tag="ACL3F5_001578"
     CDS             complement(2784..4073)
                     /gene="hisS"
                     /locus_tag="ACL3F5_001578"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0515348.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVLLETISQNFSEIFEKLGFYTQ"
     gene            complement(4150..5397)
                     /locus_tag="ACL3F5_001579"
     CDS             complement(4150..5397)
                     /locus_tag="ACL3F5_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR0515349.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFAGIRADYTRAKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLAHTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5588..6439)
                     /gene="rgg"
                     /locus_tag="ACL3F5_001580"
     CDS             complement(5588..6439)
                     /gene="rgg"
                     /locus_tag="ACL3F5_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0515350.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6563..6904
                     /locus_tag="ACL3F5_001581"
     CDS             6563..6904
                     /locus_tag="ACL3F5_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0515351.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL3F5_001582"
     CDS             complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL3F5_001582"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0515352.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9049..9981)
                     /locus_tag="ACL3F5_001583"
     CDS             complement(9049..9981)
                     /locus_tag="ACL3F5_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0515353.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEFYNAR"
     gene            complement(9978..10835)
                     /locus_tag="ACL3F5_001584"
     CDS             complement(9978..10835)
                     /locus_tag="ACL3F5_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0515354.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(10839..12185)
                     /locus_tag="ACL3F5_001585"
     CDS             complement(10839..12185)
                     /locus_tag="ACL3F5_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0515355.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12198..12482)
                     /locus_tag="ACL3F5_001586"
     CDS             complement(12198..12482)
                     /locus_tag="ACL3F5_001586"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515356.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12486..14516)
                     /locus_tag="ACL3F5_001587"
     CDS             complement(12486..14516)
                     /locus_tag="ACL3F5_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0515357.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            14708..15715
                     /locus_tag="ACL3F5_001588"
     CDS             14708..15715
                     /locus_tag="ACL3F5_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0515358.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15718..15918
                     /locus_tag="ACL3F5_001589"
     CDS             15718..15918
                     /locus_tag="ACL3F5_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0515359.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16070..16252
                     /gene="rpmF"
                     /locus_tag="ACL3F5_001590"
     CDS             16070..16252
                     /gene="rpmF"
                     /locus_tag="ACL3F5_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0515360.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            16268..16417
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001591"
     CDS             16268..16417
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0515361.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16909..>17046)
                     /locus_tag="ACL3F5_001592"
     CDS             complement(16909..>17046)
                     /locus_tag="ACL3F5_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515362.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         5524 a         3598 c         2901 g         5023 t
ORIGIN      
        1 acctgcggct agcttcctag tttactcttt gattttcatt gagtataata caaaaatccg
       61 atgaacttca ccggactctt ttattttgaa tttttgcctg ctttacgctt ttcagcgatt
      121 tcggctgcct ttcgaggcaa gacaatttcc gttatgtaag ccgtcccaaa acgcagtaca
      181 cctgcaatag gagcaaagac aactgctaga tagttataga agaaatcgcc tttgaaggca
      241 taagctagcg ctccaatgat gaaaaataga acgactgcct gaatcactgc tactaaaatt
      301 actcgtttca tgtgacctcc tgactctatt atagcatgag aatcatcaaa aagccgacta
      361 aattattcaa agcgtgaaga gaaatactgt agaccagacc ttttctgcta atgtaagcca
      421 aacccaaact aaaaccaagg ctaaaataga caaaaaattg ttgcacatca cctggaaaat
      481 gaatcaaggc aaatagaaga ctagatacca gaagaaaaat cagggttcgt ttactattgt
      541 cctgcttagg aaagagatag cgtgctaaca tccctctaaa aacaatctct tccgtcaaag
      601 gagcaaaaat aaccacagca aagaatgaga aaagtggttg agaaaaggtc aagtctgtcg
      661 ctatttgttg atttactgaa ggatcatctg gcaagaagaa ttgaacgacc agagataaga
      721 accaaaccaa gacaggaagc caaataaatc gattaaagcc gctcttctca atatgaacag
      781 gagccttctg ataccatttg taaatgccgt acacatatac tccagccaag gccacataga
      841 gtagagtaac agcatagggt gaagcgccta aagcaagcga cgcagtcgcg agcccctgaa
      901 taaagccata gataaataaa aaggatagaa gggctagaag aatccagcca aggtttttaa
      961 gtaatttcat agataactcc tttatttgaa ataacgtttt accataggta actgcatcac
     1021 attgatataa acatggatgg ctcctacaag caagaaagct agtaactgaa tctctcctgt
     1081 caagaaagaa atgataataa gaaaaatata taaggctggt aagacatatt ggtgtaattg
     1141 gaataaaatt cgaaaactct gttccaaatt agcctgacgc tccccttcat cataagaatt
     1201 tatatagttc aagacatcct ttggtgtagc gaaaaattcc aaatcaaact gacgaacaat
     1261 cgcaatggtt ttaaaaagag atttttgagc gactaagaat accacaaaga gtaagaaaga
     1321 aaggaaaaat gtttgagggt ttgtatgcaa tataatcacc tcacttaatg aaataaaaat
     1381 agccaatgga atcgctacac ctgtaatatt aaaagcaatg gttccaaact caagattccg
     1441 atacatttgc acataatagg tttcattcag atcgtcatcc atttcctctt gatacaagga
     1501 atgaaatttt ctgcttttct ttaagaaatt gaaagtcaaa agcatactaa tgaaacctat
     1561 cagtaaacaa atagctgata tccatggcat caaggctttt acatctaaaa taatttcgtg
     1621 ggattcgaca cgtgccttaa acatccctac aaacatgccc aagaaccccc ccaagacaat
     1681 agacatcaaa aataacaatc tacgtttctt tttcatattc attctccttt ttcacttgct
     1741 agatttttgg atttcttttc aatccattaa attactggga tgagagcaaa gtagacccaa
     1801 acaaattggt cgctttgata gggattaaac cagcttaggt ccatcccaat cagtagaaat
     1861 acactgacta ataaagctat gaccactaca taataaatca ctttatactt gttcatcact
     1921 cgtcctcctc caaacgaaat accgattcga ctgtttcgtt gaaaatttga gatattttca
     1981 gggcaatgat aatggatggg gtgtactcat cccgttctag taggctaatg gtctgtctgg
     2041 aaacccctgc cagtttggct aggtcggttt gattgagacc atcgcgagct cgaagctctt
     2101 ttagacgatt ttttagttgc acgttacaca cctactctcc gtcaaattca acggtttgga
     2161 tatcttcaat acgttgcaac ttgaattttt cttttcccgt attatctaca cgtcgtagct
     2221 ttacccattc ctcatcaaca tccacaactt cccagttatc tggcccaata tacactcccg
     2281 ttataattgg tttctttcca atcatttctt gcaataatct cgacatctct gcgtttcctt
     2341 tctcttttcg ctcaagtttt ttgattttat tctctagttt cttgattttt ttagaattat
     2401 tagaataaaa gaaaataata aatagtataa atcctagtac ccacatcata gctcctttct
     2461 tcttttctct taacttgctt acattgtaac acatcttttt ctttttgaca agtatagttg
     2521 tcaaaaagtt tatgattttt gtcattttgc aaaataaaaa ggtcaggagt aagttcctga
     2581 ccactttatc tatcattaat actcttcgaa aatctcttca aaccacgtca gcttcacctt
     2641 gccgtaggta tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga
     2701 gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag
     2761 cttcctagtt tgctctttga tttttattga gtataaaatc ctagtttttc aaagatttct
     2821 gagaagtttt ggctgattgt ctcaagtaac acttgcactt cttctcgggt ttggttgttc
     2881 ttgactgtca cttgtctgct ttcgacttcg ctctctccta gggtgatgag ggtcttagcc
     2941 gcaaagacat ctgctgactt gaactgagct ttgagcttac ggttgaggta atcacgctct
     3001 gctttgaaac cttgttggcg aagagcttgg actagttcta gggctttgac atttgctcca
     3061 tcacccaaga ctgcgatata gacatctagg gcattttcga tagggagggc cacgccttgt
     3121 ttttcaagga tgagaagcag gcgctctaca ccaagcccaa aaccaaatcc agcagtttca
     3181 gggcctccaa agtaagcaac caaaccatcg tagcgaccac ccgcacagac tgtcaagtca
     3241 ttgccctcaa tctctgtgat aaactcgaaa atggtgtggt tgtagtagtc cagaccacgc
     3301 accatattgg tatcgatgat gtaatctact ccaagatttt ccaacatctg acgcacagca
     3361 tcaaaatgag cttggctttc ttcatcaaga aagtccaaga tagacggcgc attctctact
     3421 gccaccttgt cttctttttc cttagagtcc aagacacgaa gaggattttc ctccaagcga
     3481 cgttggctat ccttagacaa ggtctccttg agcggtgtca aatagtcaat caaggcttgg
     3541 cggtaggctg cacggctctc aggatttcca agagtgttga ggtgcaattt gacaccttga
     3601 ataccgattt ccttcaaaaa atgggctgcc ataacgattg tttccacatc ggtagctgga
     3661 ttgctagagc caaaacactc aacaccaatc tggtggaatt ggcgcaagcg ccctgcctgt
     3721 ggacgctcat aacggaacat aggtcccata tagtagaact tgcttggctt ttgcacttct
     3781 ggggcgaaga gtttattttc cacataggca cggacaacgg gcgcagttcc ttctggacgg
     3841 agagtaatat ggcggtcacc cttgtcataa aaatcgtaca tttccttggt tacgatatcc
     3901 gttgtatctc cgacagagcg actgataacc tcgtaatgct caaaaatagg cgtgcgcact
     3961 tctgcatagt tatagcgctt gaaaatctca cgggcaaagc cctcaacgta ctgccacttg
     4021 gcagattcag caggtaaaat atcctgcgtt ccttttggtt tttgtaattt catagggaat
     4081 cctctttaaa cttaatagtc ttattttacc ataaatagag ggattaaaac agtaagaaaa
     4141 aattaggatt tagatatcat ttttgagatt aagaattgtc aaaaaaatag ctagcaagga
     4201 aagaccaaca aatagcatcc aagtcaactg catgttccat acggctacta gtgaaaaaca
     4261 agctgttccc acaggtatgg ataaggtaaa caatagacct aaaaaattac tagtatgagc
     4321 tagaacctct ggagctagat ttttcatgag catggcacta atctttggtt gaactttacc
     4381 agacacatac agagtaaaga agagaaatag caaaccaagc acgacttgat tgaataaatt
     4441 agccaaacca actagactaa gtcctacggt cgcccacatc atcaatctag gcaaggactg
     4501 cttcccaaaa taatcattgc ccgtaaggct actgatgatg attgctacta aaacacagaa
     4561 ttgattgata aatagtgcct ctgtataaga aaaattcaag agagaatggc tcaaaaagaa
     4621 gatattataa attccaccca aagcgccacc caaggaatta ataagcaaga cagcaaagag
     4681 cataaaacca aagtttttct gcccactttt aagaaaaacg agacgtaaat ttcggtaaat
     4741 tgttaggaac tggtctttga tagaaagctt ctcatttttt aagttttcac catcagcaga
     4801 tgacattgac aggctcaatt tgctttttcc taaaaagagg atagtggctg atactaggaa
     4861 aaagcaggca ttgattcccg caacgagaga aaaattgttg accgatagag ctaagagcca
     4921 gactccgaaa gcttgaccac caatagctga aatataggtg atgaactgtg aaaaagaata
     4981 agcctccatc aaatcatctt cagctacttt ttccttaata agaggcatac gcaggccacc
     5041 tgcaaaatca ctgatgatat cactaatgac attgatcaaa cacaggctag aaaaggcaaa
     5101 taaactagct tgctgaacaa ctagggctgc cagaaaaaat aaaaccgcct gaaacaaacc
     5161 gctatagacc atccatttga ccttggccct cgtgtaatct gcccgaatcc ctgcaaaaac
     5221 tgtaaagaga gtcggaagaa gcatgacaat attcgccata gcaacagcaa aagatgcttg
     5281 tgacaaggtc gatgcataga cgataaagac cagattgaaa atcgaagcac caaaagcatt
     5341 gaagaagcgt gataaagtca aaattctata agctggattt ctaaacaata gtttcataga
     5401 taatctccct ccttgttcta agttctacat caagaatagc tttagtatag cacttatgaa
     5461 tttgcgaaac gattcttttg aatatatgca acaaataaaa tgagcaaaaa aacgatagaa
     5521 cttttgtaat gacctgagag agggcaatag ttctatcgct tcaaattttt tcttggtttg
     5581 cagatattca acattcggtc gtatttctat agtattcggc agatttatta cagccaagca
     5641 tctcaaaaat acggacagca tcctccatct ttttctggcc ttccttgact ctaccttgct
     5701 tgctatcaag gagaccttct gcccacagat aaacaattcg gaaataggtc tcattttcct
     5761 tgtagaaatg ctcttcgata acacgtttaa aataataggc attggtaaat tcttcacact
     5821 caatactagc taaaaagcca ttcaatagta tagtatgaaa aaggtttcga ttgccagaca
     5881 tttccattag aaaatcagat ttacgtacca tttctcgtac atatctagta aaaagagaaa
     5941 cagataaaaa tggagaactg actgaaaata aattgagttc atagattccc cagatctcgg
     6001 tagaaaacaa ataatcatga aggacttttc cttcctctgc tgttaactct accctttcat
     6061 ctatgctctt catataagac ttgatcataa tggcatttag aatatgtttc tgtttgttgt
     6121 gagaatgggc atgcttttga tactccctgc gatataagtc ctcaagaggt gctatattct
     6181 ttggttccaa gacatctgta atttcttttc tcaactcaga atctgtatca tactggaaac
     6241 ctctcgccag aaagaggatc tcctccacac tggcagatat attttccaga gcaaatagaa
     6301 acttttccac cgaaagctca ctctgacctg tttcaaaacg ggacaacata gacggcgaaa
     6361 attgtcctcc ggttgcttgt ctcagtgaga tatttcttga ttctcgtaat tgtctaaaga
     6421 cttttccaat ctgctccata gacttcccct tgattccgta ttttcttcat tttatcatat
     6481 ttttcagaaa attcatcaaa aacttgccaa attgtcagaa ttatgagaaa atagaggata
     6541 tttatcacgt ggagggactg ctatgagaga cgatatcaaa atcaatgacc gtgctttggc
     6601 cttgcaagac caaattatcg aaaaactaga gaaagttttt gatacagatg tggaattgga
     6661 tgtttacaat ctaggtctga tttatgaaat caatctggat gaaacggggc tctgcaagat
     6721 tgtcatgacc ttcaccgata ctgcctgtga ttgcgccgaa agcctgccta ttgaaatcgt
     6781 ggcaggtctg aaacaaatcg agggtatcaa agatatcaag gttgaagtta cctggtcgcc
     6841 tgcttggaaa atcacacgaa tcagtcgcta tggccgtatt gcccttggac taccacctcg
     6901 ttaagcaggc caatcacttt taaagatgaa aaaagcaagc cgaaaatggc ttgctttttg
     6961 atactcaatg aaaatcaaag ggcaaactag aaaactagcc gcaggttgct caaaacactg
     7021 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
     7081 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
     7141 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
     7201 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
     7261 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
     7321 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
     7381 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
     7441 ttaccaacaa tcattgaaga aagtgacagc atctcaggca taccaggacc acctttaggt
     7501 ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag aacggcctga
     7561 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
     7621 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
     7681 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
     7741 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
     7801 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
     7861 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
     7921 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
     7981 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtaatagc atcttcaaag
     8041 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
     8101 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
     8161 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
     8221 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
     8281 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
     8341 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
     8401 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
     8461 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
     8521 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtctgc tacggtaatg
     8581 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
     8641 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
     8701 atcggtgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
     8761 gatttaacca tgctgtcata gatgctactg cggtgacgtt tatctaattc agtcatctta
     8821 tccctcccat ttcaattttt actattatag cacaattttc gcatgaagaa cagaataaaa
     8881 ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa aaacaacaaa
     8941 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
     9001 cgtaatgtaa tttttacaga aattctttca gaacagtgta tttaacatct atcttgcatt
     9061 ataaaactct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
     9121 ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat gaatttttgt
     9181 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
     9241 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
     9301 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
     9361 aactcgaata cttggagcaa ccattatacc agaagcaacg attacaagat cttcaccatg
     9421 tcttaactca atgtagcctt tagaaaaatc ctctccacct tgatacacag gaactggagc
     9481 ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt tcaatatttc
     9541 acgaaattgg atatcatcag ttgcttcaaa aatgatcgat ttaggaatta aacgtaacaa
     9601 tccaatttct tcaaatggca tatgtgtccc accattcatt tctgcagtta ctcctgcatc
     9661 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
     9721 tacccttcgt gaagaaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
     9781 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
     9841 tccaaagtcc ttttcaagat tatgagtagc catcgaactt gacaaatcgg cttctaagac
     9901 tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata catgccgtaa
     9961 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    10021 gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga tttcatttct
    10081 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    10141 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    10201 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    10261 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    10321 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccttc atttaactca
    10381 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    10441 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    10501 gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa agaatataag
    10561 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    10621 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    10681 attatttcac cataaagcac tgctaaaact tctacgatag acagacttcc tccgtaatgt
    10741 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    10801 cttaacccat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    10861 tttttaataa aggatactcc aaacataact gctaaaataa gaacaagacc aatcacaatg
    10921 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    10981 gcatctgaga aagttgatcc ttggaaaccg agtcctccca aaactggcat taaaaagact
    11041 gggagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc acgaacacca
    11101 ccagatgcat tcccaataac acctgcagtc gctccacaga agaaatgagg cacaacgcct
    11161 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaata
    11221 aaactagaga taaatccaat tagaactgca ttaggtgcat aagtataaac aatcggacaa
    11281 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    11341 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    11401 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    11461 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    11521 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    11581 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    11641 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    11701 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat gagaggcaag
    11761 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    11821 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    11881 attcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc tacagctaca
    11941 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    12001 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    12061 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    12121 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    12181 atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    12241 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    12301 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    12361 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    12421 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    12481 attatctaat cctcctgttt aattatcatt ttaatatcat tatagttttt tgatgatatt
    12541 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    12601 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    12661 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    12721 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggcccaaac
    12781 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    12841 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    12901 taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttcg atcatttttt
    12961 tgataaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    13021 cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa attcggaaaa
    13081 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    13141 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    13201 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    13261 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    13321 gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    13381 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    13441 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    13501 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    13561 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    13621 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    13681 tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga aaacaccgta
    13741 tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc ttgaataaca
    13801 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    13861 atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac tagctgtagc
    13921 ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga atacccccaa
    13981 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    14041 atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    14101 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    14161 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    14221 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    14281 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    14341 cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac taaataatct
    14401 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc atataatgat
    14461 agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    14521 cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt atttgagcac
    14581 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attatttttc
    14641 aactttctat tgactttata aattaaagtg atatcattta gatatcaaat aacaggaggt
    14701 cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg cattgattct
    14761 cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg gttcggaaaa
    14821 catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag ctcatgctgg
    14881 tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta actatacagg
    14941 taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag tcaaccctgc
    15001 aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt ttttaggagc
    15061 taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga tttccctcaa
    15121 agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa accctgtaga
    15181 aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct tcaacgttga
    15241 taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata ttgtccgcat
    15301 ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag cagatgaagg
    15361 tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa tccaaagtcg
    15421 tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag cttatgctcc
    15481 agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg atgcacggaa
    15541 gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc tcaatgaagg
    15601 ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc tccttgtcgt
    15661 tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt actaaagatg
    15721 gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata cgctgcactc
    15781 gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata tctcctcaca
    15841 gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat tgacgaacca
    15901 tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag aattttttca
    15961 tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag tatggttgat
    16021 gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa tggcagtacc
    16081 tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca aagtaacagc
    16141 tccatctgta aactttgacg aaactactgg agattactca cgttctcacc gtgtatcact
    16201 taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat aatagaaggg
    16261 agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac gcttgtacct
    16321 tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat actcaccaaa
    16381 acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga atcaatacag
    16441 aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt gtaagggaaa
    16501 tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg attcggacaa
    16561 ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat ttttcaaata
    16621 acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag ttaaaataag
    16681 ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta aggtatattc
    16741 aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat tcttaaaatt
    16801 ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct tcctacatat
    16861 gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct atcctaccca
    16921 ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta ataaatctcc
    16981 tgaattatag gtatagtacc atttaccaga aactgtaaac caaccagtag ccattgaacc
    17041 tgattc
//
LOCUS       DBEJJE010000044        16386 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEJJE010000044 DBEJJE010000000
VERSION     DBEJJE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.44"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..899
                     /gene="lytB"
                     /locus_tag="ACL3F5_001593"
     CDS             <1..899
                     /gene="lytB"
                     /locus_tag="ACL3F5_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0515363.1"
                     /translation="KNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGE
                     KLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGH
                     RFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAE
                     ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNN
                     FFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASD
                     PYWGEKIASVMMKINEKLGGKD"
     gene            complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL3F5_001594"
     CDS             complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL3F5_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0515364.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL3F5_001595"
     CDS             2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL3F5_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0515365.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3198..3593
                     /locus_tag="ACL3F5_001596"
     CDS             3198..3593
                     /locus_tag="ACL3F5_001596"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0515366.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3610..4509
                     /gene="era"
                     /locus_tag="ACL3F5_001597"
     CDS             3610..4509
                     /gene="era"
                     /locus_tag="ACL3F5_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0515367.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4558..5382
                     /gene="mutM"
                     /locus_tag="ACL3F5_001598"
     CDS             4558..5382
                     /gene="mutM"
                     /locus_tag="ACL3F5_001598"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0515368.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQEPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQIYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5382..5987
                     /gene="coaE"
                     /locus_tag="ACL3F5_001599"
     CDS             5382..5987
                     /gene="coaE"
                     /locus_tag="ACL3F5_001599"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0515369.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRYAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5974..7173
                     /locus_tag="ACL3F5_001600"
     CDS             5974..7173
                     /locus_tag="ACL3F5_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HGR0515370.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001601"
     CDS             7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0515371.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7362..7595
                     /gene="secG"
                     /locus_tag="ACL3F5_001602"
     CDS             7362..7595
                     /gene="secG"
                     /locus_tag="ACL3F5_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0515372.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7697..10051
                     /gene="rnr"
                     /locus_tag="ACL3F5_001603"
     CDS             7697..10051
                     /gene="rnr"
                     /locus_tag="ACL3F5_001603"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0515373.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEIIFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10014..10481
                     /gene="smpB"
                     /locus_tag="ACL3F5_001604"
     CDS             10014..10481
                     /gene="smpB"
                     /locus_tag="ACL3F5_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0515374.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10497..11357
                     /gene="tehB"
                     /locus_tag="ACL3F5_001605"
     CDS             10497..11357
                     /gene="tehB"
                     /locus_tag="ACL3F5_001605"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0515375.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11430..12383
                     /gene="coiA"
                     /locus_tag="ACL3F5_001606"
     CDS             11430..12383
                     /gene="coiA"
                     /locus_tag="ACL3F5_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR0515376.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYKVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12402..14204
                     /gene="pepF"
                     /locus_tag="ACL3F5_001607"
     CDS             12402..14204
                     /gene="pepF"
                     /locus_tag="ACL3F5_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0515377.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14206..14919
                     /locus_tag="ACL3F5_001608"
     CDS             14206..14919
                     /locus_tag="ACL3F5_001608"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0515378.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14986..15927
                     /gene="prsA"
                     /locus_tag="ACL3F5_001609"
     CDS             14986..15927
                     /gene="prsA"
                     /locus_tag="ACL3F5_001609"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0515379.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16046..>16386)
                     /locus_tag="ACL3F5_001610"
     CDS             complement(16046..>16386)
                     /locus_tag="ACL3F5_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515380.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEQTFKSLNQLERAIIDYIDYYNNKRIKIKLKGLS
                     SVQYRTKSFG"
BASE COUNT         4926 a         3069 c         3676 g         4715 t
ORIGIN      
        1 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
       61 aagctacaaa tgaaaatgct gcttactatc aagtagtgcc tgtcacagcc aatgtttatg
      121 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
      181 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
      241 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
      301 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
      361 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
      421 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
      481 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
      541 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgctctttat ctccttgccc
      601 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
      661 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
      721 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
      781 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
      841 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
      901 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
      961 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
     1021 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
     1081 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
     1141 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
     1201 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
     1261 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
     1321 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
     1381 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
     1441 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
     1501 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
     1561 ggagtcagag ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg
     1621 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
     1681 tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg
     1741 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
     1801 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
     1861 aaaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
     1921 ggcttggttt cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
     1981 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
     2041 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
     2101 ttgagagatt ttgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
     2161 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
     2221 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
     2281 tctccaatct cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc
     2341 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
     2401 ggttgggctg gattttcaaa agtcgtttgg gttagctgaa tgcgtccaaa aactggatgg
     2461 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
     2521 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
     2581 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
     2641 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
     2701 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
     2761 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga
     2821 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctgga
     2881 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
     2941 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
     3001 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggctga
     3061 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
     3121 tattaacggc tatgatcact acactccgga agaagaagcg gagatgttcg gtttacaaga
     3181 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgact
     3241 tgatatccag tttagaattt gctttgacag gtatttttac tgctatcaag gaagaacgca
     3301 atatgcgaaa acacgcagtg acggctctag tggtcatcct tgcaggtttt gtttttcagg
     3361 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
     3421 ttatcaattc tgctatcgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
     3481 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
     3541 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
     3601 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
     3661 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
     3721 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
     3781 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
     3841 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
     3901 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
     3961 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
     4021 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
     4081 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
     4141 tctgatcaaa tcacagacca tccagaacgt ttcttagttt cagaaatggt tcgcgagaaa
     4201 gtcttgcacc taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
     4261 aaacgagacg aagagacaga caaggttcat atccgtgcaa ccatcatggt cgagcgcgat
     4321 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
     4381 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
     4441 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
     4501 gaatactaag tagaggtagg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
     4561 cctgaattac ctgaggttga aaccgtttgt cgtggcttag aaaaattgat tataggaaag
     4621 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
     4681 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
     4741 ttttatctga cagacaaggt cttgatttcc catttgcgga tggagggcaa gtatttttac
     4801 tatccagacc aagaacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
     4861 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
     4921 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
     4981 gatttacagg tctttcaagc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
     5041 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
     5101 gctcaggttc atccagctag accttcccag actttgacag cagaagaagc gactgccatt
     5161 catgaccaga ccattgctgt tttgggccag gctgttgaaa aaggtggctc caccattcgg
     5221 acttatacca atgcctttgg ggaagatgga agcatgcagg actttcatca gatctatgat
     5281 aagactggtc aagaatgtgt acgctgtggt accatcattg agaaaattca actaggcgga
     5341 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
     5401 tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
     5461 ttcaagcagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
     5521 ttgaggctct agtacagcac tttgggcaag aaatcattct tgaaaacgga gaactcaatc
     5581 gccctctcct agctagtctc atcttttcaa atcctgaaga gcaaaaatgg tctaatcaaa
     5641 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
     5701 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
     5761 ctgagacttg gttggtctat gtggaccgat atgcccaagt agaacgctta atgaaaaggg
     5821 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
     5881 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
     5941 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
     6001 ctgcgtattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
     6061 tttatgccca tcttcgtgga aaatctaggt gtagggagtc agcaagtcgc tttttatgca
     6121 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
     6181 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
     6241 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
     6301 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
     6361 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
     6421 actggtccct ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta
     6481 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
     6541 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
     6601 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
     6661 tcgattggcc ctattttggc tctttatgta cgcgacttag ggcagacaga gaatcttctt
     6721 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gcatgatgag tgcaggagtt
     6781 atgggaaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccaattttat
     6841 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
     6901 cgattcctct ttggcttggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
     6961 aaaatgactc ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat
     7021 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
     7081 gctgtctttt atgcgacgag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
     7141 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaatcaat ctcaaatgct
     7201 cctcttgtgg cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
     7261 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
     7321 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
     7381 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
     7441 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgc agtaaagctc
     7501 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
     7561 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
     7621 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
     7681 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
     7741 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
     7801 gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt cgctttgaag aagatggcag
     7861 tctgaccttg gaagccaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
     7921 taaaaatggt tttggttttg tcagcctaga aggggaagag gacgaccttt ttgtagggaa
     7981 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
     8041 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
     8101 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag cctaagtatg ctggctatat
     8161 tcgttcaaaa aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaagtt
     8221 agaaggaaca gaagttctca aggtctttat cgataaatac ccaagcaaga aacatgattt
     8281 ctttgtcgcg agtgttctcg atgtggtggg acactcaacg gatgtcggaa ttgatgttct
     8341 tgaggttttg gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc
     8401 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
     8461 tgaaattatc tttaccattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat
     8521 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcttatta
     8581 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
     8641 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
     8701 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
     8761 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
     8821 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaataccata aaattgtacc
     8881 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
     8941 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
     9001 tgatatcgtt cttcggcagc gtggcattgc cgagcggatg attgagtctt ttatgttgat
     9061 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctaccgaat
     9121 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
     9181 cttgcgcatt tatgggactg ccagtgagat tagccaggag gcacttcaag acatcatgcg
     9241 tgctgttgag ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca
     9301 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
     9361 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
     9421 ttacggccgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
     9481 ccagtcttcc aaccgtgaac gtcgtgctat agaagctgag cgtgaagtcg aagccatgaa
     9541 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
     9601 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
     9661 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
     9721 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
     9781 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
     9841 gaaacagtct agtcgtagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
     9901 agacaagaga aaatcaggac gctcaaatga taagcgtaaa cattcacaaa aagacaagaa
     9961 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    10021 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    10081 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    10141 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    10201 ttcatatcgc accttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    10261 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    10321 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    10381 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    10441 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    10501 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagctg
    10561 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    10621 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    10681 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    10741 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    10801 acaataccaa acctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    10861 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    10921 ttgatgtgac ggctgtagat caaaatggac tggctcttga aatcttgcaa agcattgtgg
    10981 agcaggaaga tttggacata cctgttgacc tttacgatat caattcagct agcattggac
    11041 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    11101 cagctattat tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt
    11161 gtgccatgga cacggaggac tatccttgct cggttaactt cccattcacc tttaaagaag
    11221 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    11281 atttgcatcg tcgcgatgag aatggcaatc gtattcaact acgctttgcg actttactag
    11341 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    11401 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    11461 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    11521 gccagatcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    11581 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    11641 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    11701 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    11761 tgcctcagaa agtccttaaa gagcgaagtg agggctatcg tagtcagggt tacaaagtac
    11821 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    11881 ttctgtattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    11941 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    12001 aggaattttc ctatggtcaa ggtagtttat tggaaatatt gcgtcttccc tataagagac
    12061 aaaaaatatc tcattttaca gtttctgagg acaaggacat ctgtcgctat atccggcaac
    12121 aactttatta tcaaaatctc ttttggatga aagaacaagc agaagcctat caaaagggag
    12181 aaaatatcct gacttatggg ctgaaagaat ggtatccaca aattcgacca atagtgggca
    12241 aatttttcca gattgaacaa gacttgacta gctattatca gcatttttat acctattacc
    12301 aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc agccttttat cagcaatatt
    12361 tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct aatggtatta caaagaaatg
    12421 aaataaatga aaaagataca tgggatctat caacgatcta cccaactgac caggcttggg
    12481 aagaagcctt aaaagattta acagaacaat tggagacagt agcccagtat gaaggccatc
    12541 tcttggatag tgcggataac ctactagaaa tcactgaatt ttctcttgaa atggaacgcc
    12601 agatagagaa gctttacgtt tatgctcata tgaagaatga ccaggataca cgtgaagcta
    12661 agtatcaaga gtactatgcc aaggccatga cattctacag ccagttagac caagcctttt
    12721 cattctatga gcctgaattt atggagatta gcgaaaagca gtatgctgac tttttagaag
    12781 ctcaaccaaa gctgcaggtt tatcaacact attttgacaa gctcttgcaa ggcaaggatc
    12841 acgttctttc acaacgtgaa gaagaattat tggctggagc tggagaaatc tttggttcag
    12901 caagtgaaac cttcgctatc ttggacaatg cggatattgt gttcccttat gtcctagacg
    12961 atgatggtaa agaagttcag ctatctcatg ggacttacac acgtttgatg gagtctaaaa
    13021 aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc gacttacgaa caattccaac
    13081 acacctatgc caaaaccttg caaaccaatg ttaaggtgca aaattaccgt gctaaagttc
    13141 gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt
    13201 atgacaattt ggtagcagca gttcgcaagc atttgccact cttacatcgc tatcttgagc
    13261 ttcgttcaaa aatcttgggg atttcagatc tcaagatgta cgatgtctac acaccgcttt
    13321 catctgttga atacagtttt acctaccaag aagccttgaa aaaagcagaa gatgctttgg
    13381 cagtcttggg tgaggattac ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg
    13441 atgtttacga aaatcaaggc aagcgttcag gtgcctactc tggtggttct tacgatacca
    13501 atgcctttat gcttctcaac tggcaagaca atctggacaa tctctttact cttgttcatg
    13561 aaacaggtca cagtatgcat tcaagctata ctcgtgaaac tcagccttat gtttacgggg
    13621 attactctat ctttttggct gagattgcct caactaccaa tgaaaatatc ttgacggaga
    13681 aattattgga agaagtggaa gacgacgcaa cacgctttgc tattctcaat aacttcctag
    13741 atggtttccg tggaacagtt ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc
    13801 accaagcaga tcaaaatggg gaggtcttga caagcgattt cctaaataaa ctctacgcag
    13861 acttgaacca agagtattat ggtttgagta aggaagacaa tcctgaaatc caatacgagt
    13921 gggctcgcat tccacacttc tactataact actatgtata tcaatattca actggctttg
    13981 cggccgcctc agccttggct gaaaaaattg tccatggtag tcaagaagac cgtgaccgct
    14041 atatcgacta cctcaaggca ggtaagtcgg actatccact taatgtcatg agaaaagctg
    14101 gtgttgatat ggagaaggaa gactacctca acgatgcctt tgcagtcttt gaacgccgtt
    14161 taaatgagtt tgaagccctt gttgaaaaat taggattggc ataaaatggt tgaatcgtat
    14221 agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg
    14281 atgcgtcagc gtcaaaagca ggtcacaggt ttcttgaaag aattggaaga ctttgcccgc
    14341 aaggaaaata ttcctattat tccccatgaa acggttgctt atttccgttt tcttatggaa
    14401 accatgcagc ctaaaaatat tctggaaatt gggacggcta tcggtttttc agctctcttg
    14461 atggctgaac atgcgccaaa tgctaagatt acaactattg atcgtaatcc agaaatgatt
    14521 ggttttgcca aggaaaattt tgcccagttt gacagtcgca agcaaatcac tctcctagag
    14581 ggagatgcgg tggatgtctt atctacactg acagagtctt atgatttcgt ctttatggat
    14641 tctgccaagt ctaaatacat cgtctttctg ccagaaatcc tcaaacattt ggaagttggt
    14701 ggtgtggttg tcttggatga tatttttcaa ggtggtgatg ttgccaagga tattatggaa
    14761 gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa aattatttga tgcaacctta
    14821 gacaatccag aactcaccgc aacattagtg cctttaggag atggtattct catgcttcgt
    14881 aaaaatgtag cagatgttca actgtctgaa agcgaatgat tttcagaaaa atttaagaaa
    14941 aaatagtaaa atagatagag taacacttat ctcaaaggag tagacatgaa gaaaaaatta
    15001 ttggcaggtg ccatcacact attatcagta gcaactttag cagcttgttc gaaagggtca
    15061 gaaggtgcag accttatcag catgaaaggg gatgtcatta cagaacatca attttatgag
    15121 caagtgaaaa gcaacccttc agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt
    15181 tttgaaaaac aatatggctc agagcttgat gataaagagg ttgatgatac tattgccgaa
    15241 gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt cacaagcagg tatgactctt
    15301 gaaacacgta aagctcaaat tcgtacaagt aaattagttg agttggcagt taagaaggta
    15361 gcagaagctg aattgacaga tgaagcctat aagaaagcct ttgatgagta cactccagat
    15421 gtaacggctc aaatcatccg tcttaataat gaagataagg ccaaagaagt tctcgaaaaa
    15481 gccaaggcag aaggtgctga ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa
    15541 acaaaagaaa atggtggaga aattaccttt gattctgctt caacagaagt acctgagcaa
    15601 gtcaaaaaag ccgctttcgc cttagatgtg gatggtgttt ctgatgtgat tacagcaact
    15661 ggcacacaag cctacagtag ccaatattac attgtaaaac tcactaagaa aacagaaaaa
    15721 tcatctaata ttgatgacta caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa
    15781 aatgattcaa catttgttca aagcattatc ggaaaagaat tgcaagcagc caatatcaag
    15841 gttaaggacc aagccttcca aaatatcttt acccaatata tcggtggtgg agattcaagc
    15901 tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga gtcagggaaa aaactcgact
    15961 tcaggaaaaa atgaagcaaa cattcccaca ataaaacgca tagtacaagg tttgtactgc
    16021 cccccaaaaa agttagacaa ttaatttatc cgaaggattt agttctgtat tgcacagagc
    16081 taagtccttt tagttttatc ttaattctct tattgttgta ataatcaata tagtctataa
    16141 tggctcgttc caattgatta agtgatttaa atgtttgctc atagccataa aacatttcgg
    16201 attttaaaat gccaaagaaa gattccatcc taccgttgtc ttggctgttt cctttgcgtg
    16261 acatagatgc ttgaattccc ttactctcta ggaagcgatg ataagaatcg tgttgatatt
    16321 gccagccttg gtcactatgg agaatcgtat tctcgtagtg cttctctttg aatgcctgtt
    16381 ccaaca
//
LOCUS       DBEJJE010000045        15085 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEJJE010000045 DBEJJE010000000
VERSION     DBEJJE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.45"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            129..926
                     /locus_tag="ACL3F5_001611"
     CDS             129..926
                     /locus_tag="ACL3F5_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0515381.1"
                     /translation="MISSEFISKIEFACNKKEGLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1074..2333
                     /locus_tag="ACL3F5_001612"
                     /pseudo
     CDS             1074..2333
                     /locus_tag="ACL3F5_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2429..3703
                     /locus_tag="ACL3F5_001613"
     CDS             2429..3703
                     /locus_tag="ACL3F5_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0515382.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3713..4591
                     /gene="truB"
                     /locus_tag="ACL3F5_001614"
     CDS             3713..4591
                     /gene="truB"
                     /locus_tag="ACL3F5_001614"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0515383.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4832..5134
                     /locus_tag="ACL3F5_001615"
     CDS             4832..5134
                     /locus_tag="ACL3F5_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0515384.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFSLWIAKAPSQERGRLAFLQMLAQILQGFR"
     gene            5242..5880
                     /gene="udk"
                     /locus_tag="ACL3F5_001616"
     CDS             5242..5880
                     /gene="udk"
                     /locus_tag="ACL3F5_001616"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0515385.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            6008..7348
                     /gene="xseA"
                     /locus_tag="ACL3F5_001617"
     CDS             6008..7348
                     /gene="xseA"
                     /locus_tag="ACL3F5_001617"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0515386.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQSRTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7326..7538
                     /locus_tag="ACL3F5_001618"
     CDS             7326..7538
                     /locus_tag="ACL3F5_001618"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0515387.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7535..8410
                     /locus_tag="ACL3F5_001619"
     CDS             7535..8410
                     /locus_tag="ACL3F5_001619"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0515388.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8403..9218
                     /locus_tag="ACL3F5_001620"
     CDS             8403..9218
                     /locus_tag="ACL3F5_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0515389.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9211..9642
                     /locus_tag="ACL3F5_001621"
     CDS             9211..9642
                     /locus_tag="ACL3F5_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0515390.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9649..11316
                     /gene="recN"
                     /locus_tag="ACL3F5_001622"
     CDS             9649..11316
                     /gene="recN"
                     /locus_tag="ACL3F5_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0515391.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11318..12046
                     /locus_tag="ACL3F5_001623"
     CDS             11318..12046
                     /locus_tag="ACL3F5_001623"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0515392.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12125..13948
                     /gene="lepA"
                     /locus_tag="ACL3F5_001624"
     CDS             12125..13948
                     /gene="lepA"
                     /locus_tag="ACL3F5_001624"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0515393.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            14361..14836
                     /locus_tag="ACL3F5_001625"
                     /pseudo
     CDS             14361..14836
                     /locus_tag="ACL3F5_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14874..>15085
                     /locus_tag="ACL3F5_001626"
     CDS             14874..>15085
                     /locus_tag="ACL3F5_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGR0515394.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPV"
BASE COUNT         4508 a         2728 c         3542 g         4307 t
ORIGIN      
        1 tgttttagaa gtagaggtgt actattctag tttcaatcta ctataaactt ttatgaaata
       61 cagaaaacgc ttcctaaaac ctaaagtttg tgatataatt atcaagaaaa aagatttagg
      121 agtttattat gatttcttca gaatttatct caaagattga atttgcttgc aataagaaag
      181 aaggtcttta tagtcaaagc aaatttaagt atgcgattcg ttcgatattc gcaggtgcat
      241 ttttaacctt cagtactgct gcaggtgcag ttggggctga cttgattaat aaaattgcac
      301 caggtagtgg acgcttcctc tttccattcg tttttgcttg gggcttggcc tacattgttt
      361 ttttgaatgc cgagttggtc acttcaaaca tgatgttctt gactgctggt agtttcttaa
      421 aaaaaatctc ttggagaaaa acagctgaga ttttactata ctgtaccttg ttcaacctta
      481 tcggagcctt gatagcaggg tggggctttg ctcattcggc agcctatgcg aatctgatac
      541 acgatagttt catttcaggt gttgttgaga tgaagttagg ccgctcaaat gaattggtct
      601 tgcttgaggc gattttggca aatattttcg taaatattgc gattctgtca tttattttgg
      661 tcaaagatgg tggtgccaaa ctttggcttg tgttgtcagc tatttacatg tttgtattct
      721 taacaaacga gcacattgcg gcgaactttg cttctttcgc gattgtgaaa ttcagtgttg
      781 ctgcggattc aattgccaac ttcggtgttg gaaatatgct tcgccactgg ggtgtgactt
      841 tcatcggaaa ctttatcgga ggaggcctct tgatgggtct tccatatgcc ttcctcaata
      901 aaaacgaaga tacttatgta gattaagaaa atgagcacga ttgagtcgtg cttttttcat
      961 tttcaaaata aggtaatagc tatttcttat atcaaaatat agaaaactga tatttgtaaa
     1021 ctataactca aggtgctaca atatccttaa taaaatgata tggaggtcac cttatgactt
     1081 gtgattttaa atttgaaact ctacaactac atgctggtca agttgtggct ccagctacta
     1141 agtctcgtgc agtgccgatt tatcaaacaa catcttttat ttttgatgac acgtaggaag
     1201 gtgctgatct gtttgccttg aggaaaccag ggaacattta tactcgtatc accaatccta
     1261 caacagctgc ccttgaaggt ggtgttgaag cgctagcaac agcatcaggt atgactgcag
     1321 tgacttatac gattttggcg cttgcccatg ctggtgacca tgtagtggct gcttcgacta
     1381 tttacggtgg aaccttcaat cttttgaaag aaccccttcc tcgttatggt atcacaacaa
     1441 cctttgtcga tgttgataat ttggaggaag tagaagcagc tatcaaagac aataccaagc
     1501 ttgtcttgat tgaaaccttg ggtaactcct tgattaatat tccagacctg gaaaaactgg
     1561 cagagattgc tcataaacat caaatcccac ttgtgtcaga caatactttt gcaatacctt
     1621 atttgattaa cgtcttctct catggcgttg acattgccat tcactctgcg actaagttta
     1681 tcggtgggca tggtacaact attggaggaa taattgtcga tagtggtcgt tttgactgga
     1741 tggcttcagg gaaattccct caatttgttg acgagggttc aagctgccac aatttgagct
     1801 atactcgtga tgtgggtgca gtagccttta ttatagctgt tcgagttcaa ttgcttcgtg
     1861 atacaggtgc agccttgtca ccattcaatg ctttcctctt gctacaaaga cttgaaaccc
     1921 tttcacttcg tgtggaacgc catgtacaaa atgctgagac aattgttgat tttcttgtca
     1981 accatcctaa ggtagaaaag gtaaattatc caaaacttgc agatagtcct tattatgcct
     2041 tggctgagaa atacttgcca aaaggtgtcg gttcaatctt taccttccac gtcaaaggtg
     2101 acgaggaaga agcacgcaag gtcattgata atttagaaat cttttctgac cttgcaaacg
     2161 cggcagatgc taaatcgctt gttgtccatc cagcaacaat cactcacggt caattgtcag
     2221 aaaaagacct agaagcagca ggtgtcacac caaatcaaat ccacttgtct atcggtcttg
     2281 aaaatgtaga agatttgatt gaagacttac gcttggcctt ggaaaaaatt taaagtaaaa
     2341 gaagataaac agtgggtttt gactcactgt ttttgatttt ccctcaggca tgatataatg
     2401 gttacagaag tctagaaaga ggaatgtaat gaacgaaatc aaatgtccca actgtgggga
     2461 agtctttaca gtaaatgaaa gccagtatgc tgaacttttg tcccaagtga gaacggcaga
     2521 gtttgataag gaactacacg ataggatgag gcaggaactg gccttggctg agcaaaaggc
     2581 tatgaatgag caacagacta aactggctca gaaggatcaa gaaattgcgc aattgcagag
     2641 tcaaatccaa aactttgata cagaaaaaga attggccaag aaagaagttg aacagacaag
     2701 ccatcaggcc ttattggcta aggacaagga agtacaggcc ttggaaaacc agttggcgac
     2761 cttgcgtttg gagcatgaaa atcaattgca aaagaccctt tctgacctag aaaaagaacg
     2821 caatcaggtc aaaaatcagc tcctactgca agaaaaggaa aatgagttgt ctttggcttc
     2881 tgttaagcaa aactacgaag cccagctcaa agcagccagt gaacaagtcg agttttataa
     2941 gaattttaag gctcaacaat ctacaaaagc gattggggaa agcctagaac agtatgcaga
     3001 gagtgagttt aacaaggttc gtagtttcgc ctttccaaat gcttactttg agaaggataa
     3061 caaggtctct tcgcgtgggt ctaaagggga ctttatcttc cgtgagtgtg atgaaaatgg
     3121 agttgaaatc atttctatca tgtttgagat gaaaaacgaa gcggacggaa cagagaagaa
     3181 gcacaagaat gcagattttt acaaggaatt ggacaaggac cgtcgggaga agaactgtga
     3241 gtatgccgtt ttggtgacca tgcttgaggc tgataatgac tactttaaca cagggattgt
     3301 tgacgtcagt cacgagtatg aaaaaatgta tgttgttcgt cctcaattct ttatccaatt
     3361 gattggtctc ttacgtaatg cggcgctaaa ttccctaaaa tacaagcagg agttggcctt
     3421 ggttcgcgag caaaatattg acattacgca ttttgaggaa gacttggatg cctttaagct
     3481 agcttttgct aagaactata attcagcttc gactaacttt ggaaaagcta ttgatgaaat
     3541 cgacaaggcc atcaaacgca tggaagaggt taagaaattc ctgactacat ctgaaaacca
     3601 actccgtcta gctaacaaca aattggaaga tgtctctgtt aaaaaattga cccggaaaaa
     3661 tccaacaatg aaagcgaagt tcgaagcatt gaagggggag tagaaagcaa aaatgaacgg
     3721 tattatcaac ttaaaaaaag aagcaggaat gacctcgcat gatgcggttt ttaaactgcg
     3781 taagattttg ggaaccaaga aaattggtca tggcggaacc ttggatccgg atgtggtggg
     3841 tgttttgccg attgcggttg gcaaggcgac acgcatggtc gagtttatgc aggacgaggg
     3901 taagatctat gagggggaaa tcactctggg ctattccacg acgactgagg atgctagtgg
     3961 ggaagtggtc gcagaaaccc ctgttttgtc tcccttggat gaaaagcttg ttgatgaagc
     4021 gattgctagc ttgactgggc ctattaccca gattccccct atgtattcgg cagttaaggt
     4081 taatggtcgc aagctctatg agtatgcgcg tgctggtcag gaagtggagc gtccagaacg
     4141 tcaggtgacc atttatcaat ttgagcgaac aagtccgatt tcttatgatg gccaacttgc
     4201 ccgattcact tttcgtgtaa aatgcagtaa agggacttac atccgtactt tgtcagttga
     4261 tttgggtgaa aagcttggtt atgcggctca tatgtcccat ttgactcgta ctagtgctgc
     4321 tggcttacaa ttagaagatg ctcttacctt ggaggaaatt gctgaaaaag tagaggctgg
     4381 gcaattagat tttctccatc ctttagagat tgggacaggt gaccttgtca aagttttcct
     4441 aactccagaa gaggctacag aagttcgctt tggtcgtttt attgagctag accaaacgga
     4501 caaagaactg gctgcctttg aagatgataa attgttagcc attctagaaa aacggggcaa
     4561 tctctataag ccaaggaagg tttttagcta gatcgtttag gaataaaaat cgggtgatag
     4621 ataacaattg cttgataaaa ccccatacta atagtagaat ggttttggga attataatat
     4681 tccaattgtt gcgagttgta ggtactcaaa taatctatat agaaatttag aggtgtgaaa
     4741 tgaagcaatt taaaattctt tcagataaat atttagagtc cattacaggt tctggtggga
     4801 acttaggccc aggatttggt gtgataattc catgatgcga aatgagtttc gagaaagggt
     4861 ggagcaactt cttcaacaaa aagaaataaa tgaaaatagt gagttgagtc acctgtttcg
     4921 tcttgctata caaaatttag acagaaatga aaaacaccaa tcggtcatgg ccaatttgag
     4981 tcaagggttg tcactttacc tcatgacgca tcattaccag gcacctaagt ctgtcattga
     5041 ttttagttta tggattgcca aagctcctag ccaggaaaga gggaggctgg ctttcttgca
     5101 gatgcttgct caaatcctac agggctttcg ttaaaactgt cgaacatcag agggaagact
     5161 ctggtgtttt ttgctgatga gactataaat tttgtaaaaa atgtgataga atagacgacg
     5221 gataaaataa cggaggatag catgcaaaat agaccaatca ttattggagt gacaggtggt
     5281 tctggtggtg gtaaaaccag tgtttcaaga gccattttat cgcattttcc tgatgaaaag
     5341 atttccatga ttgagcatga ttcatactac aaggatcagt ctcatttgac ctttgaagag
     5401 cgtgtcaaaa ccaactatga ccatcctttt gcctttgata cagacttgat gatcgagcag
     5461 attaaggaat tgttggcagg gcgtccggtg gacatcccga cctacgacta tacagagcat
     5521 acacggagta gcaagaccta tcgtcaggag cctcaagatg tctttatcgt tgagggcatt
     5581 ttggtcttgg aggacaagcg tctgcgcgat ttgatggata tcaagatttt tgtggatacg
     5641 gatgacgatg tgcgtattat tcgtcgtatc aagcgtgata tggaggagcg tggccgtagc
     5701 cttgatagcg ttattaacca gtacttaggt gtggtcaaac caatgtacca ccagtttatc
     5761 gagtcaacta agcgttatgc tgatatcgtc attcctgaag gggttagcaa taccgtggct
     5821 atcgacctgt tgacgaccaa gattgcaaag attttggaag aagctcgaaa cagcaaataa
     5881 tcacatgtgg aggccttgcc tcctttttct atttttccct cataatggta cataaatgga
     5941 gatttttagg catatttttg gtataataat acccataaaa gagcaagtaa atgaatagta
     6001 ggtggagatg gaaaagtatt tatcggtaac aactttgacc aaatatctga aaatgaaatt
     6061 cgataaagac ccatacttgg aacgggtcta tttaactggt caagtttcca actttcgtaa
     6121 acgacctact caccaatatt tctccctaaa ggatgaccat gcagttattc aagcgaccat
     6181 ctggtctggg atttatcaga aattagggtt tgacctggaa gaaggaatga agatcaatgt
     6241 gattgggcgt gtacaggtct atgaaccaag tggtagctac tccatcatca ttgaaaaagc
     6301 tgagcctgat ggggttgggg cgcttgcgat tcagtttgaa caacttaaga aaaaattgac
     6361 agaagaaggc ctgtttcaag aacgcttcaa gcaagctcta ccccaatttt ctaagagaat
     6421 tggtgtagta accagccgta gtggagccgt tattcgagat attatcacga ccgtcagcag
     6481 gcgattccca ggtgttgaca tccttcttta tccgaccaag gttcaaggtg aaggggctgc
     6541 ggaggaaatt gctagaaata ttgcgcgtgc taatcaacgg gacgatttgg atttgctcat
     6601 tattggtcgt ggaggtggtt ctattgagga tctctgggcc tttaacgaag aaattgtggt
     6661 acgagctatt tttgaatctc gtttgccagt tatctctagt gtggggcatg agacggatgt
     6721 gaccttggca gattttgtgg cagatcgacg cgctgcaacg ccaacagcgg cggctgaact
     6781 ggcaacacct gtgaccaagt tggatgtatt agctcatttg caaaatcagg aaaaacggat
     6841 ggtaacggca gtccgaaatg ttctatctaa gaaacaagag gctttgaaaa aatgcagtca
     6901 gtctgttatc tttagacaac ctgagcgctt gtatgacggt tatttgcaac gcttggacca
     6961 actgcaactg cgtttgaaac aaagtttgcg aactcggatt tctgataaca aacaattagt
     7021 tcaatcaaga actcatcaat tagtacaatt atcacctgtt accaaaatcc aacgctatca
     7081 agaccgttta ggacagttgg acaagctctt aggtagccaa atggcgttag tttatgacgc
     7141 caaggttgct gaggccaagc gactttcgga agctttgctc atgttggata ctagccgaat
     7201 cgtggcgcgt ggttatgcta ttgtcaaaaa agaagagtcc gttgtagatt cggttgagag
     7261 tttgaagaaa aaagaccaag taacgctttt gatgcgagat ggtcaagtag aattagaggt
     7321 taaagatgtc aaaacaaaag aaatttgagg aaaatctagc agaactggaa accattgtcc
     7381 aaagtttgga aaatggtgaa attgctctgg aagatgcgat tactgccttt caaaagggca
     7441 tggtcttgtc aaaagagctc caagctacgc tggacaaggc tgaaaagacc ttggtcaagg
     7501 tcatgcaaga agacggaaca gaaagtgatt ttgaatgaaa aagcaagaaa aattagctct
     7561 tgtcgagtcg gctttggaag atttttatgg agaccagcag tttgcctcta gtttacggga
     7621 gtctgttctc tattctattc atgctggtgg caagcgtatt cggccttttc tcttgttaga
     7681 agttctggaa gccttgcagg ttaccatcaa acctgctcac gcgcaggtag ctactgcctt
     7741 ggagatgatt catacaggga gcttgattca cgatgacctt cctgctatgg atgatgacga
     7801 ttatcgaaga gggcggttaa ccaatcacaa gaaattcggt gaagctatgg ccattttggc
     7861 tggagatgcc ttattcttag actcatatgc cttgattgcg caggcagatt tgccaagtca
     7921 gatcaaggtg gacttgattg ccaacttatc ccttgcttca ggtagtctgg gtatggtggc
     7981 agggcaagtt ttggatatgg agggcgaaca ccagcacttg tctttggaag aacttcagac
     8041 tattcatgcc aataagactg ggaagttact agcctatccc ttccaagcgg cagctattat
     8101 agctgaattg tcacctgaaa tgcaggtgaa gctgaaaact gtgggtgaat tgattggact
     8161 tgcttttcaa gtcagggatg atgtactgga tgtgacagct agttttgagg aaatcggcaa
     8221 gacacctcaa aaggatctgc aggcagaaaa atcaacctat cctgccctgt tgggcttgga
     8281 agagtccatt gccttttgta accaaaccct ggatcaagct aatgaaaaat tagaagaaat
     8341 tgcccagcag cttccctttg aaacagaatc gattgtaagt gtagtagaaa gtttgagaat
     8401 caatggctaa ggaaagagtg gatgtactag cttataaaca ggggttgttt gaaacgagag
     8461 agcaggccaa gcgaggtgtg atggctggcc tagtcgtagc agtccttaat ggagaacggt
     8521 ttgacaagcc aggagagaaa attccagatg acaccgaatt aaaactcaag ggggagaaac
     8581 tcaagtatgt cagccgtggt ggtttgaaac tggaaaaggc cttgcaggtc tttgatttgt
     8641 cggtggatgg cgcgactacg attgatatcg gggcctctac tggaggtttt accgatgtca
     8701 tgctacagaa tagtgccaag ttggtctttg cagtcgatgt tggtaccaat cagttggctt
     8761 ggaaattacg ccaagaccca cgagttgtca gcatggagca gttcaatttc cgctatgctg
     8821 aaaagactga tttcgagcag gagccgagct ttgccagtat tgatgtgagt ttcatttccc
     8881 ttagtctgat tttgccagcc ttgcaccgtg tcttggctga tcaaggtcag gtggtagcac
     8941 ttgtcaaacc tcagtttgag gcaggacgtg agcagattgg gaaaaatgga attattcgag
     9001 atgctaagat tcatcagaat gtccttgaat ctgtaacagc tatggcagta gaggcaggtt
     9061 tttcagtcct tggcttggac ttttctccca tccaaggtgg acatggaaat attgaatttt
     9121 tagcgtattt gaaaaaagaa aagtcagcaa gcaatcagat tcttgctgag attaaagagg
     9181 cagtagagag ggcgcatagt caatttaaaa atgaataaaa aagaaagact tgaaaaaatt
     9241 agaagattgg tgacagatta tcaaatcggc acgcaagaag aaattgtaga acatttgaaa
     9301 gaagcaggta tcactgccac tcaggcgacg gtatcccgag atatcaaaga gttaggtatt
     9361 gtcaaaattc ctttgagaga caacacctat gtctacgaat tgccaaaatc aatcgtaaaa
     9421 agtctgcaac tggctgaaga caatatcgaa tcggctgaat tgatggataa gatgatcaat
     9481 ctccaagtta ttccaggaaa tacggctttt gtaaaagctc agttaatcga gacttttgca
     9541 gacaagattt ttagttgttt gactgatgat agctcgattt tagtcattgc cagaagtgga
     9601 agtctagcag aggaaatctt tgaacaagta aaaaattggt aggtctatat gttacttgaa
     9661 atttcgataa aaaactttgc cattattgag gctatttccc tcaattttga aaaggggatg
     9721 actgtcctga ctggtgaaac gggtgcaggg aagtcgatta tcattgatgc catgaatatg
     9781 atgttgggag ctcgtgcgac gacagatgtt attcgtcatg gtgcaccaaa ggcagagatt
     9841 gaggggcttt tctcagttga gaatagtcgc cttttacagg aaatttttga tgagcaaggt
     9901 ttagaattag gtgatgaaat tatcatccgt cgggaaatct tgcaaaatgg tcgtagtatc
     9961 agccgtgtaa atggtcagat ggttaatctg tctgttttgc gaactattgg gcaacatctt
    10021 gtagatattc atggtcagca tgaccatgag gagttaatgc gtccccaact gcatatccag
    10081 atgttggatg aatttggtga tgccgctttt tgggacttga aagaaaccta tcaaacgagt
    10141 tttgatgcct atcggaaaat gcgcaagcag gttctggaag tcaagaaaaa ccaacaggaa
    10201 cacaaggcac gtatcgaaat gttggaattt caaatggcag agattgaggc agcaaacttg
    10261 caggctggag aagacttgga tctcaatcaa gagcgagata aactcctcaa ccacaaaaat
    10321 attgcggata cactgaccaa tgcctacagt atgttggaca atgaagattt ttcaagtctg
    10381 gccaatgttc gttcagccat gaatgacatg gaaagtgtcg aagagtatga ccctgaatac
    10441 cgtgaaattt caagctctct gtctgagacc tactatgttt tagaagacat tagcaaacgt
    10501 ttggaagcta tcattgagga ccttgatttt gatggcaatc gcctcatgca ggttgagaat
    10561 cgtttggacc tccttcatac tattactcgt aagtatggtg ggactgttga tgatgttttg
    10621 ctttattttg ccaagattac ggaagaatac aatctcttga caggcaataa tctttcgtct
    10681 gaggacatgg aagcagagct taagaagttg gaagtcaatc ttgtcaattt ggcaggtcaa
    10741 cttgcttctg ctcgtcataa tttggctcag caactcgaag ctgagattaa acaagaactg
    10801 caagatcttt atatggaaaa agcccagttt caggttcgtt ttagtaaggg aaaattcagt
    10861 cgtgagggaa atgaaatggt tgagttttat atttcaacca accctggaga agactttaaa
    10921 cccttggtta aggttgcttc tggaggggaa ttatctcgtc tcatgttagc cattaagtct
    10981 gccttttcac gtaaagaagg caagactagc attgtctttg atgaagtgga tacgggagtt
    11041 tcaggtcgtg ttgctcaagc tattgctcag aaaattcata aaattggtca gcatggtcag
    11101 gttttggcta tctcccattt gccacaagta attgcgattg cagattatca attctttatt
    11161 gagaagatta gtaatgacca ttcaacggtt tcgactgttc gtctcttgac ggtcgaagag
    11221 cgagtggagg aagttgccaa gatgttggca ggtgatgatg tgacagaagc agccctgacg
    11281 caagccagag aattgttgag aaacagggag aaataagatg acagattatt atgtaattgg
    11341 agatgttcac ggaaaagctg ggatgctgga agaccttctt aaaacctggg atggtcagac
    11401 ccagttgctc tttctaggtg atttgattga cagaggtgag gatagtcacc gtgttcttga
    11461 aatggtcaag gacttggtgg acaatcaagg ggctatctgt ttgtctggaa accacgagta
    11521 tatgtttttg acttggctag atgacccaga agaaagttat gaccattatc gtcgcaatgg
    11581 tggagataca accattaact ctatcctagg tcgtcccttg gatgcaccag ttgatggagt
    11641 agaagatgcc aagcgggttg ccgctgaagc ggcagacttg gtcgaattca ttcgtcaaat
    11701 gccatttgta gtagagacag acaagtatat ctttgttcac gcaggtattg atttgacctt
    11761 ggatgactgg catgaaacaa cagattataa aaaagtatgg cttagaaaac cattccacgg
    11821 agctgaaaat catactggaa aaaccattgt cttcggtcat acaccggtct atggtttgtt
    11881 acagcaagaa cgcggtacat ctgagctttg gactacagaa gatggcaaga ttggaatgga
    11941 tggaggagct gtttatggtg gtgtccttca cgggattgtc tttacagacc aaggaatgac
    12001 agaacaccac tttatcgaaa atgacggctt tgtcgctgaa gattagtact cctagcaggg
    12061 tatggtcttg tcaaaatatc aaaaacaatt tataataaat agataccctg aaaggaagag
    12121 aatcatgaac ttagaagaat tgaaaaaacg acaggagaag atccgtaact tctctattat
    12181 cgcccatatt gaccatggaa aatcaactct agcagaccgc attttggaaa aaacagagac
    12241 ggtttcaagt cgtgaaatgc aggcccagct tttggatagc atggagctag agcgggaacg
    12301 tggaattact attaagttga atgccatcga gttgaattac actgcaaaag atggggaaac
    12361 ttatattttc catttgattg acacaccagg gcacgttgac tttacctatg aagtttcacg
    12421 ttcgctagct gcctgtgagg gtgctatttt ggtggtcgat gcggctcaag gaattgaggc
    12481 tcaaactctt gccaacgttt atctggcttt ggataatgat ttggaaatca tgcctatcat
    12541 taataaaatt gacctgccgg ctgcagatcc ggagcgcgtg cgtacagaga ttgaagatgt
    12601 gattggtttg gatgccagtg aagcagtttt ggcttctgcc aaggctggta ttgggattga
    12661 agaaatcctc gagcaaattg tagaaaaagt accagcacca acgggtgatg tgacggcgcc
    12721 acttaaggcc ttgattttcg actctgttta cgatgcttac cgtggggtta tcctccaagt
    12781 gcgtgtcatg gacggagtgg tcaaacctgg tgataagatt cagctcatga gcaatagtaa
    12841 gacctttgat gtggccgaag tcggtatttt tacaccaaaa gcggttggtc gtgatttcct
    12901 tgcgactggt gatgttggtt acattgcggc gtctatcaag acggttcagg atactcgtgt
    12961 gggtgatacc gttaccttgg caaccaatcc tgcggcagaa ccattacatg gttataagca
    13021 gatgaatcct atggtctttg cgggtctcta cccaatcgaa tcaaacaaat acaatgacct
    13081 gcgtgaagcg cttgaaaaat tgcaactgaa tgatgctagt cttcagtttg aaccagaaac
    13141 atctcaggca cttggatttg gtttccgttg tggatttctt ggacttctcc atatggatgt
    13201 tatccaggaa cgtttagagc gtgagttcaa tattgacctc atcatgacag ctccgtctgt
    13261 tatttacaaa gttaatttga ccgacggtga gtctatggat gtgtctaacc catctgagtt
    13321 tccagaccca actaagattg cgaccattga agagccttat gtcaaggcgc aaatcatggt
    13381 accacaggag ttcgtcggag cagtaatgga gctagctcag cgtaagcgtg gggactttgt
    13441 gactatggac tatattgatg ataaccgtgt caatgttatc tatcaaattc ctcttgctga
    13501 aattgtcttt gacttctttg ataaacttaa gtcttcgaca cgtggttatg caagctttga
    13561 ctacgaattg tcagaatatc gcccatctaa gctggtgaaa atggatatcc ttctcaatgg
    13621 agataaggtg gatgccctca gctttatcgt tcacaaggac tttgcctacg aacgtgggaa
    13681 actcatcgtt gataaactca agaaaatcat ccctcgccaa caatttgaag ttccaatcca
    13741 agcggctatt ggacacaaga ttgtcgctcg tactgatatc aaggcccttc gtaagaacgt
    13801 acttgctaaa tgttatggtg gtgacgtttc tcgtaagcgt aaactccttg aaaaacaaaa
    13861 agctggtaag aaacgcatga aatccatcgg atcagttgaa gttccgcaag aagccttcct
    13921 cagcgtcttg agtatggatg aagaataagt tatcagaaat gcctttcctt gttcacagga
    13981 aatttatata agaatcaata gtaaagcagg cttagatggt ctgctttttt agtttttata
    14041 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ctgtatgtat ggttactgac
    14101 ctcgtcagtt tcatctacaa cctcaaaact gtgttttgag taacctgcgg ctagcttcct
    14161 agtttgctct ttgattttca ttgagtatta gaacagaaaa atgcttggag tatttgtttg
    14221 tgtgtttatt tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa
    14281 aataatagaa agtaattaac aacgatttca tatagtgtta tacttatagc ataaagttaa
    14341 tggaaagaag ggaaaacctt atggtattag attatttctt tgacaaaaac cttgtgtttt
    14401 gcttagaagc ggataatcaa gaataacttt ttgatcaggt agcaagcttg ttggaagaac
    14461 gagaaattgt cactccaact tatcgtgaag ccttgatcac gcgtgaaaag tcatttccaa
    14521 ctggtttaga tatggaattt ctaggaaagg acttgcaaat gtaatgattc ctcacacaga
    14581 tattgttcat aatctagctg agaaagtggt ggttgttcga ttagagaaac cggtgacttt
    14641 ccataatatg attgcgccag gtaaggaagt agaagtatcc ttgctcttct ttatcatcaa
    14701 taactcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
    14761 tggacatctt gaagacctat caaaaatttc cgaaccagaa aaactttatg cttacattgc
    14821 tgaagcaacc gcttaatctt gtctattaaa aaataaaatc ggaggaaatc taaatgatta
    14881 aaattcttgc tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag
    14941 aagaagaact ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg
    15001 taaacgaaga ccttatgaaa ggttacgata tctttacacc aatcgctgca acagaccttg
    15061 gttttgaacc aggtatccca gttat
//
LOCUS       DBEJJE010000046        14628 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEJJE010000046 DBEJJE010000000
VERSION     DBEJJE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.46"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(65..1687)
                     /gene="groL"
                     /locus_tag="ACL3F5_001627"
     CDS             complement(65..1687)
                     /gene="groL"
                     /locus_tag="ACL3F5_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0515395.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1703..1987)
                     /gene="groES"
                     /locus_tag="ACL3F5_001628"
     CDS             complement(1703..1987)
                     /gene="groES"
                     /locus_tag="ACL3F5_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0515396.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2143..2538)
                     /locus_tag="ACL3F5_001629"
     CDS             complement(2143..2538)
                     /locus_tag="ACL3F5_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0515397.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2616..3377)
                     /locus_tag="ACL3F5_001630"
     CDS             complement(2616..3377)
                     /locus_tag="ACL3F5_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0515398.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3410..4036)
                     /gene="ytpR"
                     /locus_tag="ACL3F5_001631"
     CDS             complement(3410..4036)
                     /gene="ytpR"
                     /locus_tag="ACL3F5_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0515399.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4052..4369)
                     /locus_tag="ACL3F5_001632"
     CDS             complement(4052..4369)
                     /locus_tag="ACL3F5_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0515400.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4366..4665)
                     /locus_tag="ACL3F5_001633"
     CDS             complement(4366..4665)
                     /locus_tag="ACL3F5_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0515401.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4915..4995)
                     /locus_tag="ACL3F5_001634"
     CDS             complement(4915..4995)
                     /locus_tag="ACL3F5_001634"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515402.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            complement(5002..5193)
                     /locus_tag="ACL3F5_001635"
     CDS             complement(5002..5193)
                     /locus_tag="ACL3F5_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR0515403.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5354..6028)
                     /locus_tag="ACL3F5_001636"
     CDS             complement(5354..6028)
                     /locus_tag="ACL3F5_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515404.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6034..6480)
                     /locus_tag="ACL3F5_001637"
     CDS             complement(6034..6480)
                     /locus_tag="ACL3F5_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0515405.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6594..7097)
                     /locus_tag="ACL3F5_001638"
     CDS             complement(6594..7097)
                     /locus_tag="ACL3F5_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0515406.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7094..7456)
                     /locus_tag="ACL3F5_001639"
     CDS             complement(7094..7456)
                     /locus_tag="ACL3F5_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR0515407.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7522..8553)
                     /locus_tag="ACL3F5_001640"
     CDS             complement(7522..8553)
                     /locus_tag="ACL3F5_001640"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515408.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(8560..9381)
                     /locus_tag="ACL3F5_001641"
                     /pseudo
     CDS             complement(8560..9381)
                     /locus_tag="ACL3F5_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(9398..9869)
                     /locus_tag="ACL3F5_001642"
                     /pseudo
     CDS             complement(9398..9869)
                     /locus_tag="ACL3F5_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(9993..10709)
                     /locus_tag="ACL3F5_001643"
     CDS             complement(9993..10709)
                     /locus_tag="ACL3F5_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0515409.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11590..13005)
                     /gene="ply"
                     /locus_tag="ACL3F5_001644"
     CDS             complement(11590..13005)
                     /gene="ply"
                     /locus_tag="ACL3F5_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0515410.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13016..13426)
                     /locus_tag="ACL3F5_001645"
     CDS             complement(13016..13426)
                     /locus_tag="ACL3F5_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515411.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13419..14027)
                     /locus_tag="ACL3F5_001646"
     CDS             complement(13419..14027)
                     /locus_tag="ACL3F5_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515412.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14040..14498)
                     /locus_tag="ACL3F5_001647"
     CDS             complement(14040..14498)
                     /locus_tag="ACL3F5_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0515413.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
BASE COUNT         4232 a         3391 c         2663 g         4342 t
ORIGIN      
        1 ataaaaagaa gggttagtca ttccctcctt ttgtgttttt tataagttgt tttctataga
       61 aagcttacat catcccgccc atcatgcttg gatccattgc tggagctggg gctactggtt
      121 ctggtttatt ggctacgact gcttctgttg tcaaaatcaa gctggctaca gatgctgcat
      181 tttgtagggc tgaacgactc actttaactg gatcaatgat accttgatca atcatgttaa
      241 cccactcgcc agttgctgcg ttaaatccta taccaagctc agcatttttc aaacgatcga
      301 taacgataga tccttcaaat cctgcattgt gagcaatttg acgaacgggt tcttccaaag
      361 cacggagaac aatattacgt cctgttgctt catctcctgt caattccaag gtagcaacag
      421 ctggaatcac attggcaaga gctgttccac cacctgcaac aataccttct tcaacagctg
      481 cacgagtagc gttgagggca tcttcaatgc ggagtttcat ttctttcaac tcagtttcag
      541 ttgcggctcc aaccttaata accgctacac cacctgacaa tttggccaag cgttcttgca
      601 atttttcacg gtcaaattca gaagttgtag tttcgatttg agacttgata accgcaacac
      661 ggtgagaaat cgcttcagga tttcctgcac cttctacaat aaccgtgcta tctttgtcca
      721 cggtcactct cgctgcttga ccaagagctt caattgtcgc atctttcaac tcaagaccaa
      781 ggtcttctgt gataactgtt ccgcctgtta agatggcgat atcttcaagc atggctttgc
      841 gacggtcacc aaaaccaggt gccttgactg ctactacgtt gaaggttcca cgaatcttgt
      901 tcaaaacaag agttggaaga gcctcgccat ccacatcatc cgcaataatc aagagtggac
      961 gattgctttg gagaatgctt tccaaaagtg gcaagatttc ttggatattg gaaattttct
     1021 tgtctgtaat caaaatgtac ggattttcaa ggtcagccac cattttttcg ctatcagtca
     1081 ccatgtactg tgaaaggtaa ccacggtcaa actgcattcc ttctacgact tcaagctctg
     1141 tttccatacc acgtgactct tcgatggtga tgacaccgtc tttgccaact ttttccattg
     1201 cttcagagat gtactcacca actttttcag aacgagaaga tacggctgca acttgagcga
     1261 tagcttcttt attggcaaca gggatggcgt tgtttttcaa agcttcaact gctgcggcaa
     1321 ctgctgtttc aatcccacga cgaataccga ttggatttgc acctgctgtg acgtttttga
     1381 ttccttcacg gacgatagct tgggtcaaga ctgttgcagt cgtagtcccg tcacctgcga
     1441 tatcattggt tttagaagct acttctgata ctaacttggc acccatattt tcaaaatggt
     1501 cttccaattc gatttctttg gcaatggtca caccgtcatt ggtaatcaag ggtgaaccga
     1561 atgacttttc aagaacgaca ttgcgacctt ttggtcccaa ggttacttta acagtgtctg
     1621 caaggatatc gacaccacga accatggctg aacgggcatc tgatgaaaat ttaatttctt
     1681 ttgacatact tactttctcc ttctattcct caatgattgc caaaatgtta gcttcgccta
     1741 cgatgatgta cttttcatcg ccatctttga catcaagacc tgcgtgggct tcaactaaga
     1801 cacgatctcc agttttaaca cttggagcaa ccaagtcacc gttcaaggta cgaacacctt
     1861 gtccagtagc cacaacttga gctgttttgg ttttttcttg ggctgagcct gcaaggacaa
     1921 agcccccaac ggtttgttct ttttcttcta tttttaagag cacacggtcc cctaatggtt
     1981 tcaacatctg atttcctcca taatgagata gatattatta gcactctttg aactggagtg
     2041 ctaattcata attctattgt atcacttggt cagaaatagt caagaaaaaa gtctgacttt
     2101 ctcaagataa aaagcctgag accaactcag actttttaat tcttaaaatg gcaattcttc
     2161 ctcttccaag accaaatctg ccaaatcttg gcctgcatta ttttcacgca tagcacgttg
     2221 ggcacgactt tccaagagtt ggaatcctgt cacaaggact tcggttacat aattcatctg
     2281 accatttttc tcaaagcgac gggtacgcaa ttctccatca acggaaatga gactaccttt
     2341 ggttgcgtag cttgccaaag tttctgctag tctgccccat agaaccatat taacaaaatc
     2401 agcttcacgt tcaccgtttt ggtctttgta acgacggttg acagcgatag ttgctcgcgc
     2461 taccgacttg tcattgttgg ttttgtgcaa ttctggtgta gacgttaaac gcccaatcat
     2521 gataacttta ttatacatat tttcttcctc ctacttatct attcgtagga aatcaaaaaa
     2581 agttacagaa atttgtaact tttcgaggaa atttcttatt ttttatgaat catgaaacct
     2641 gtcgcctgtt gattggccat aatggtcata tctgtaatct gaacacggcg aggctgactg
     2701 gtcacataga ctactgtgtc tgcaatatcc tgagcttgca aggcttctat tccttggtaa
     2761 acggacgcag ctcgttcttt atcaccatga aaacgcactg tagaaaaatc tgtttcgaca
     2821 attccaggct gaatggtcgt caccttgata tccgttgcga tggtatcaat tcgcagtcca
     2881 tctgaaaagg tcttaactgc cgccttggtg gctgagtaaa cagctgcacc agcataggca
     2941 taaattcctg cggttgaccc catattgata atatgacctt gattggcttt taccattgct
     3001 ggcaagaaac agcgagtgac tgccatcaaa cctttgacat tggtatccaa catggtcagc
     3061 atatccaact cttcatagtc ttgataggga gctaagccaa gagccagtcc tgcgttattg
     3121 accaggatgt caatctgacc tatcgtttct aaaatatcag agcagacagt ctttaccatt
     3181 gtcatatccg tgacatctag gagaaaagtc caaactgttt gatttggaaa agtttctgca
     3241 aactccgcct taagagcttc tagtctgtct atccgtcgtc ctgttagaac gacatcctca
     3301 ccctgctcca gataagcacg cgcaatcgct tcaccgattc ctgaggttgc tcccgtaatc
     3361 actacatttt ttgccatctt atttccttct atcagatgct gacaagttcc taggcagtcc
     3421 agtgtttcgc tgggtcgaac ggtgttccga caacttggtc ttctgataat tcaagcaccc
     3481 cacgtttttg cggagcattt ggcaaatgca attcacgagg actacacatc atcccaaaac
     3541 tcttttcacc acgaagttcg cctgggaaaa tgaaattccc ttttggcatc atggcaccag
     3601 gaagagccac aatggttttc aacccaacac gcgcattagg tgctcctgca acgatttgca
     3661 ctatcttgtc acttgcgact gcaacttggc agatgttgag gtggtcactg tctggatgag
     3721 ctaccatctc gacaatttca ccaacaacaa acttaggttc cttatcatta acaatttctt
     3781 ctgtaaaacc ttccgcctgt aattcttggt tcaaacgagc gacttgctca tctgataaaa
     3841 agacttgacc gcgctctgca atttcaaaca agctcgaaac ctcaaaaatg ttccaagcta
     3901 ctgtttcccc attttctttg aggaaaacac gggctacctt gcctttgcgt tccacattca
     3961 gtttggcatc tccgctattt ttcacgatga ccataaggac atcaccgaca tgttctttgt
     4021 tatacgtaaa aatcattgtt tccttttttt cctatttcaa tcctgctaaa aaatcgttaa
     4081 tttgctcctt acttttacgg tcgcgattga caaaacgacc gatttccttg tccttttcta
     4141 gaacaacaag gctaggaatt ccgtaaacat cccagagttt ggccaaatcc atatactgat
     4201 ctcggtccat tcgaataaag gtgaactctg gattggtctc ctcaatctct ggtaaggcag
     4261 gataaatata acgacaatcg ccacaccagt ctgccacaaa aaggaagacc ttcttgcccg
     4321 ctttttccac taaagatgct aattcttcta aacttgctgg ctgtatcata agacttcctc
     4381 ctcatagact aggtcttcat tttcatagac aaaggtataa tgacgaccat cctcaaaaat
     4441 gacgccacca accaagctct ccagactgct ttcgtaaact tgaacataga gggtcgcaat
     4501 ttcccccatg tcggaaaaat ggtctcgcac aatctctgtc aactcttcct gagtcttcat
     4561 gagcttacgg tcatctgcaa cttttttcgt ggcaagagca aggcttccga tacctagcag
     4621 agccaagcct gccatccaca tttttttagc tttcatacca ttcattttaa cacaaaaaag
     4681 gcttcaggac aaatgaggaa gcagcagaaa agcaagtaaa aagcctcttc ctttaaggaa
     4741 aaggacttct tatactcaat gaaaatcaaa gaccaaacta ggaagctagc cgcaggctgc
     4801 tcaaagcact gctttgaggt tgtagataga actgacgaag tcagctcaaa acactgtttt
     4861 gaggttgtgg atgaagctga cgtggtttga agagattttc aaagagtatt attcttattg
     4921 ccaggcacct aagttgccaa cgtagtaacc atcaggtgtg taggtattgc gaagcatctt
     4981 acctgatgaa gccagataat actacttgcc attgtctttg acccaatcat tcgcaatcat
     5041 ggaaccagaa gaacttacat aataccattc tcccttgtca taaacccaag tactgacttt
     5101 catggttcct gagcaattaa aggcaaaaaa actgtccaat atcattcgtt ttttaaaagc
     5161 atttgacact acatcatcta cgctgtagta catagataca tcaaacgtaa aagccaaaat
     5221 atcgaaaaat atacaacttt taaaggcagc atttcatttt ttaaagtcta acaaccatag
     5281 aactgaaatc agagcaaggc atcaatttcc tactcttagt acgtctattt tgatggttga
     5341 agtgaagatt tttttattta acgtagacaa tttccaactt cccaaaagcc acatctccac
     5401 ggatagtcaa ggttttgctg gttggggcta caggagcgtc agccttagct gcaccaaagg
     5461 aggtttctac tttcaaatct acacgccagt gttgtggaac atagacggtt gcatttccga
     5521 aggccacttc aatatttaaa gttgcaaaat cacctagcat ctctgcatta tcatagtaga
     5581 ttttagcatc cccaaaagcg acttccactt ggtcatctac gagatcttga tcttgcttat
     5641 agaaggtccc gctaccaaaa gcgacttcct tatccgtgac gactgttttt ttcccattgt
     5701 accaccattt tttttcattc cagaacttac ttgaatgcgt cagataacca acaccaagta
     5761 ccaccaagat gctagcccaa ataagagaat gattggtaac tggtaacaag tcataagcgt
     5821 aatttgcaat gatgatcgcc agtaaacctg taaaaactgc cgaagtgaga tgacgtctaa
     5881 ggatggactc aatggactta taagcaaaaa aaacaatacc tagtaaaggc catattttac
     5941 catccaaaga aggaattcca aaattccctt gcagcaagat ccaagctgct aaaaccaata
     6001 aaacaatacc aaatgctttc tttttcatgt tttttacctc atgtttctta gattttcttt
     6061 taggagggat tggtaatgcc gtgagacatg aacctccttg tgcgtctgat aaaaggaaat
     6121 ggtgcccgtt cctgaaaagg acttgtccac tgagtaaatc tgacggatgt ttgcgatcgt
     6181 tgacttggaa actcgattaa aatagcgagg caagatagac tccaactcat agagcttgag
     6241 gcgaacctca taagcttcct tctggttatg agcgtagatc ttgctccctt ctgtttcaaa
     6301 gaagagaatt tctgacaggt ctagataata ttcacctgtc cccttgtaaa aagtcaacct
     6361 cggagccttt gactcttgca agagccgttg caagtctgca atttcatctg tcaaagtggg
     6421 ggtcttgatg acaatttcag tctcctctaa attgccgtca atctcaattc gtaacttcat
     6481 cacatctcct ttctgactct actatatcaa agctaagtta ggaatacaag ggcaaaaaag
     6541 caagtggtca atttgaagca gtaagtggtt gtaggactag cttaacttac atgtcagaat
     6601 aggaagaaaa ggaatcccca caccaaacca caagcatagc caaccaagac atccttggga
     6661 taatgaacac cccctaaaac cctcaccaac cccagcaaag ctgaaaagat caagcatact
     6721 aagccaatag gtagactagc atgcagacag gccatggaga tgatagttgc cgaaaagaca
     6781 tggcgactgg gcatcgaccg tcccgaacta tccttatcaa gaaggggaca gatatcccaa
     6841 gtttcataag gtctcgggtg attgattttc ttacgaaaca gggacaaggt cacaaaacct
     6901 gatgcaggaa taagcacata aaccccaact tgctgaccaa gtcctagttg caggtaagtg
     6961 gtgactagca agatcagata gaccaggggc atggcgactg tcatcaaacg attgaaactg
     7021 cgtaatagga ataaaagaat tggacgacta gttagtctgg agctgatatt tcgataccat
     7081 tcttgataat ttttcattta tgcttctcat acttttctag aacttgttga gatgttttcc
     7141 ccttggcaag ccaatccact agcttgtcca agcgacgtat ttcctgcatc agaggatcat
     7201 caatttcctc aatacggaca ccgcaaatct tccctgtaat tgcaattcgt tcagggacat
     7261 aatatggtgc ttgtcgaaaa aaatctccgt aagtaacatc cctatccaga caagcaagaa
     7321 cgtcactcac ttcataccct gtcaaccaac tggtcacttg gtgaactgac tctgcctttc
     7381 caccctttcg ctcaactttt gcaatcaagg ctaagtagac agcagcaaat ttcatattgt
     7441 ataatttctg actcatactt ctctctttct atgtgtacta gtataaataa gaaaaagaag
     7501 gccgtcaagc cttcttttga tttattcttc tgcttcatct tctgtaaatt gactattgta
     7561 caagtcagcg tagaagccac cttgcgccat cagttcctca tagttgcctt gctcgatgat
     7621 atttccatct ttcatgacca agatcaagtc tgcatttcgg atggttgaca agcggtgggc
     7681 aatgacaaag gatgtgcgtc cttccatcaa acggtccatg gctttttgga tcaattcctc
     7741 tgtccgtgtg tcaacagaag aagtcgcctc atccaaaatc aaaagcggtg catccttaag
     7801 aagggcacga gcaatagtca atagttgttt ttgtcctaca gacaaggtca cggtgtcatc
     7861 caagatggta tcatagccat ctggcaaggt cataataaag tggtgaattc ccacagcctt
     7921 actagcttcc atcattcgtt catcactaat ccctatttga ttatagatga gattgtctcg
     7981 aatagttcct tcaaagagcc aggtatcctg caagaccatt gaaaaggcat catgcacttc
     8041 tgaacgcgtc atagccttgg tatccacacc atcaatgtga atacttccct tatcaatctc
     8101 atagaatttc atcaaaagat tgacaatggt tgtcttacca gtcccagtcg gcccaacaat
     8161 ggcaaccttt tgaccagcat gagctgtcgc agagaagtca tagtcttgaa cattgacacc
     8221 gtccaccaga atttctcctg ctgacacgtc gtagaaacgt ggaatcagat tgaccagagt
     8281 tgatttacca gaacctgttg acccaataaa ggccactgtt tgaccagttt ctgctttaaa
     8341 gctaacatgt tcaataactg cctccgaatt tgccgcatag cggaaggtca catccttaaa
     8401 ctcgacctga cctttgaagt tttcatcagt cagctgcact tgaacagggt tttggataga
     8461 agaatgcaaa tctaaaactt gattaatccg cttagcagag accatagttc ggggaagaac
     8521 gatgaagagt gctcccatga gaaggaagcc catgacaacc tacatggcat aagacatgaa
     8581 aacaatcatg tcactaaaga gaggcagacg cgctatcgaa gcagcgtcgt taatcacata
     8641 ggccccaatc cagtaaatcg ctacactcaa accacttgaa atccccatca tgataggatt
     8701 caaaatagcc ataagacggt tgacaaacaa attcaaacgg gtcaattcat catttactgc
     8761 tgcaaatttt tcattttgat aatcctctgc attgtaggca cgaacgacac gaatacctgt
     8821 taaactctca cgagtgatac tgttcagttt atctgtcaac ccctgaatca aggactgttt
     8881 tggaaaggct agcgtcatca aaacggtcgt catcaggacg ttgacaatca ctaccacaag
     8941 tacggcccag agtcagtatt ctgaatgacc taaaatcttc ccaatagccc agatagccat
     9001 aattggacca cgcgttacca cttgcaagcc catagtaatc aacatttgaa cttgagtaat
     9061 gtcattggta gtacgcgtca agaggctagg aattgaaaat ttcttaatct ctgtctgcga
     9121 gtaatccaaa actcggttaa aaatatcact tctcagccta ctagtataag aagccgccac
     9181 tcgggatgca aaaaatccaa ctgcaactac ggacaaaaag gcaagaaaga gcattcccat
     9241 catcatgctt gccggctgcc acaactcatc taaattagtt tcttgactac ctagcaaatc
     9301 cgtaattttc gagatatagg tcggcacttc caactctaga tagaccgaaa agcaagtaaa
     9361 gagaatggct agtaaaatca tcccccattc ttttctacta attcttttgg ttaatttctt
     9421 tattctctcc tcctattccc ttgatatttt gcctgtagtt gaccgagaac tttctcaaaa
     9481 atcagtaatt catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa
     9541 gccttaacct gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc
     9601 ttatcaacag gactcgcctc caattccacc aaaccatttt gcactatacg cttaaccaga
     9661 ttactagcaa cagacttggt aatattgagt tcctgctcga tatctttaat caagaccaag
     9721 tcttggtttt tctagcgatt atccaaaaaa cgcacaacct gaccttgcgg cccacccata
     9781 aattcaatgc cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa
     9841 cgcttaaaga ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc
     9901 tggagaataa ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt
     9961 ttctcactta ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc
    10021 ttttggacgt cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct
    10081 tcgcctgaca attccacttc tgactgagga atcatttcca attcagtcac ttggaattct
    10141 tcaataccag actcacggag agcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa
    10201 actgtgattg taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat
    10261 tgctcaaaga ctgcgtctgc atcttcacct ccaaatacaa taacaccttt gttgtcaaag
    10321 aggtaagaaa cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg
    10381 acattggctg ctgtacggtt gacgttagaa gtcaaagtat ccacaattag catagagcca
    10441 tttggcccaa aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct
    10501 ttatcaatcg ctttatcgat aatgtgtttt ggcacttggg cttgtttagc acggtcgata
    10561 acgaatttca aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag
    10621 atttctacac caaattttgc atatacctta gagttagctc catctttagc cgttttcttg
    10681 gctacgatat tggcccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt
    10741 tattattata acacaagttt ttttgatttt cactagagga aatggatttt attagcaaat
    10801 caagctagga tagcacttta cctgctaaga tggtcttacc tttctatctt tatcaacaga
    10861 cactcatcca cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca
    10921 agtttgacaa agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca
    10981 atcatactgc accttttgtt gacagtctac tccagacata tcatagttca agtaaatact
    11041 ttgaaattca acagttctta taggcgctat tgtattctaa gaaatcaata gaagagtttc
    11101 taagcaaacc tctaatactc aataaaaatc aaagagcaaa ccagaaagct agccgcaggt
    11161 tgctcaaaac actgttttga ggttgcggat ggggctgaca tggtttgaag agattttcga
    11221 agagtataat ttacgtgttc ccaagatgga gaagttagac tagtacactg gcacttctaa
    11281 accattgcta gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta
    11341 gatataaaca gcaaaatatt tccgatacgt gtcgttcttg aatttccaat catctaaaac
    11401 aagtaaagga taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta
    11461 cacattctgt ttgatagatt cattttaaca tcacgagcat actccaatgg aaatcgctag
    11521 gcaagagata aactttcaga tatccgcaga gagatcatcg cctctttttg tcgcaagcat
    11581 tctcctctcc tagtcatttt ctaccttatc ttctacctga ggatagagag ttgttcccca
    11641 aatagaaatc gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca
    11701 ccattcccag gcaagcccgg tacactctct aattttgaca gagagattac gaacattccc
    11761 ttttaaagga atactagtgg taaagtgagc cgttaaatcc tgcccatttc tgtcccaagc
    11821 cttaggagtc aagacttcct taccttgatg atcataggat aattcattcc aagtaatata
    11881 atattgggca acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt
    11941 aaccttagtc tcaacatagt ctgtactatt ttgaaaggtc gcaactacat tgtcacgtaa
    12001 aaaagaagtt gtataggaaa tcggcaagcc tggatgatct gctgtaaagc gactgccttc
    12061 ttgaatcaag tcctctacca tatccacctt gcctgttaca actcgggcac ccgaacttgg
    12121 gtcgccccct aaaataaccg ccttcacttc tgtattgtcc aaaatctgtt tccactctgt
    12181 ctgaggagct accttgactc cttttatcaa agcttcaaaa gcagcctcta cttcatcact
    12241 cttactcgtg gtttccaact tgagatagac ttggcgccca taagcaacac tcgaaatata
    12301 gaccaaagga cgctctgcag aaattcctct ctgttttaaa tcctctaccg ttacagtatc
    12361 ttgaaacaca tctcctggat ttttaacagc atctacgctg actgtataat aaatctgctt
    12421 aaaattaaca atctgaatct gcttttcgcc cgaatggaca gagttaaaat caatatcaag
    12481 agaattccct gtcttttcaa agtcagaacc aaacttgacc ttgagttgtt ccatgctgtg
    12541 agccgtgatt ttttcatact gcattctagc tgggacatta ttgacctgac cataatcttg
    12601 atgccactta gccaacaaat cgtttaccgc tccgcgaaca cttgaattgc tggggtcttc
    12661 cacttggaga aagctatcgc tacttgccaa accaggcaaa tcaatactat aagtcatcgg
    12721 agcacgatcg accgcaagaa gagtgggatt attctctaac aaggtctcat ccactacgag
    12781 aagtgctcca ggatagaggc gactgtcgtt ggtagctgtt acagaaatat cacttgtatt
    12841 tgtcgacaag ctccgcttct ttctttcgat aacaacaaac tcatcgggta gctgattacc
    12901 ctctttgatg aaacgatttt caatactttc tccctgatgg gtcaagagtt tctttttatc
    12961 gtaattcata gctagtataa agtcatttac tgctttattt gccatcttct acctcctaat
    13021 aagttcctgg attgagttgc ataaactcag acttgttcag cgaaatcagc cgtggttgga
    13081 ctaagtaatc caaaatttcc tcgtacaatt cttctgagac attgcgtcgc cgtctggcta
    13141 gataagaagt cggaatgacc gtattatcca acataaatac cttatctaag tcaatcaagg
    13201 ttggtcttgt aaaaggatta cgagctagat ccggctcttc tatcataaag ttcttgacca
    13261 aacgtctggt caagagagct ggtttgaagg tctgattttt aaccaactct ttgtttttag
    13321 tcatgctgtt gtcaatacag atatacatat gattcttcac agccaaatcg ctactaatag
    13381 tcggaaaagg caaataaaga gctacaacat ctcctctctt aatcaagcaa gagcaccccc
    13441 ttttctccta atgtaacata gacaggattg accaagtctt ctgattgact cagaatttcc
    13501 aaagtttgag tttggcgcgc tgtcaattta gtagcatctt gtctcttcaa tacaaaatgc
    13561 ttgtcgccaa taaccttgac aatataatcc ttctccaaag ctgactggta aatccacatc
    13621 agatgttgtc tgtcctgaga actcaagaga gaaggatttt caagcctccc gatagtctga
    13681 taaaaatcaa aaacaggagc taactcctgc caatctgatt ggctagttgt caaggctaga
    13741 aaaagggctt tgcgagctga tacttcttgg ttagccttga gagttacttt cccctccaag
    13801 ttttttagaa atcgggaaac tccagaaagc aaatttttct ctaactgcga gaaataaaaa
    13861 cctttcgttc ctagacataa gtctttcatg tcgctttctc tagcaaataa gagctcaaac
    13921 atttgatagt aaaagaaaaa tatctggcac tgggtcgcgc tcatcttttc cttatcggct
    13981 tcttttttta accagagcaa gggcgacagg tagctggatt gagacatttc ctctacctcc
    14041 tactcttttt taactggagc atctgcacta gctgccactt cttttgactg gatactttcc
    14101 cactggttaa tctcctctga gataagacct tcgcatgtct tgacaaatag ggcaaaagcc
    14161 ttggtctttc ctgcatattt ctccgtttgg cattgataga ggaatttttc tttctccagg
    14221 agttgcgcag ttttttggta agaaatccaa ttttcctttg cattatacaa attgataatc
    14281 ccctcacaca gcaagccgag actggataag gcaaccgaaa tcaaacggta gcgatcacct
    14341 ggcataggaa tagcacaaaa gacagctatg aggaaacctg ccacgatttc tgttattttt
    14401 aataccttat agcgcctacg atgttgaacg cttttcttta aaaaatgagc tatctgtacg
    14461 tctaatcgct ctgtcaggta catttcttct ggcgtcatat tcgtaactcc tttcatttac
    14521 tttgataatc atagtataac atatttgaat atcaaagtat agtaaaaact ggactataac
    14581 ttattagact tcctgcgaaa caaaacatgg tatagtagtt ctatgaat
//
LOCUS       DBEJJE010000047        14469 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEJJE010000047 DBEJJE010000000
VERSION     DBEJJE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.47"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(57..1193)
                     /gene="dnaJ"
                     /locus_tag="ACL3F5_001648"
     CDS             complement(57..1193)
                     /gene="dnaJ"
                     /locus_tag="ACL3F5_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0515414.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1595..1951)
                     /locus_tag="ACL3F5_001649"
     CDS             complement(1595..1951)
                     /locus_tag="ACL3F5_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR0515415.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1953..3776)
                     /gene="dnaK"
                     /locus_tag="ACL3F5_001650"
     CDS             complement(1953..3776)
                     /gene="dnaK"
                     /locus_tag="ACL3F5_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0515416.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4256..4780)
                     /gene="grpE"
                     /locus_tag="ACL3F5_001651"
     CDS             complement(4256..4780)
                     /gene="grpE"
                     /locus_tag="ACL3F5_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0515417.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4807..5841)
                     /gene="hrcA"
                     /locus_tag="ACL3F5_001652"
     CDS             complement(4807..5841)
                     /gene="hrcA"
                     /locus_tag="ACL3F5_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0515418.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6005..6514)
                     /locus_tag="ACL3F5_001653"
     CDS             complement(6005..6514)
                     /locus_tag="ACL3F5_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR0515419.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7122..9455
                     /gene="hsdR"
                     /locus_tag="ACL3F5_001654"
     CDS             7122..9455
                     /gene="hsdR"
                     /locus_tag="ACL3F5_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0515420.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSITEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTANKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9468..10931
                     /locus_tag="ACL3F5_001655"
     CDS             9468..10931
                     /locus_tag="ACL3F5_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0515421.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10931..12499
                     /locus_tag="ACL3F5_001656"
     CDS             10931..12499
                     /locus_tag="ACL3F5_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0515422.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            12556..13353
                     /gene="psrA"
                     /locus_tag="ACL3F5_001657"
     CDS             12556..13353
                     /gene="psrA"
                     /locus_tag="ACL3F5_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0515423.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            13364..13972
                     /locus_tag="ACL3F5_001658"
     CDS             13364..13972
                     /locus_tag="ACL3F5_001658"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0515424.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(13920..>14469)
                     /locus_tag="ACL3F5_001659"
     CDS             complement(13920..>14469)
                     /locus_tag="ACL3F5_001659"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0515425.1"
                     /translation="PMNWVVIKIKDIFSINTGLSYKKGDLSINNKGIRIIRGGNIKPL
                     EFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFI
                     FQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPF
                     EEQELITQKVEKLFEKVNQLWK"
BASE COUNT         4588 a         2674 c         2727 g         4480 t
ORIGIN      
        1 aaccataccc atggcaaggc aacgctgacg tggtttgaag agattttcga agagtattat
       61 tctccatcaa aggcatcttt tatatggtca aagaagcctt ttttctttgg atttactttc
      121 aagtcaccag cagccgcgaa ttctttcaag gctacttttt ggcggtcgtt caagcctgtc
      181 ggtgttacga cattaacagt aacgtattgg tcaccaactg caccgccacg aaggctcggt
      241 gcccccttac tacgtaggcg gaatttctta ccagtctgag ttccctctgg aataaccaat
      301 tcaacatcac cgtgaacagt tggaatatct actgtatcac caagagccgc ttggacaaag
      361 ttgaggttga gattgtagaa gatagtcgtt ccttcacgtt caaacttgtc gctagcttct
      421 acagaaacta ctacatacaa gtccccataa ggtccaccgt taaagcctgc ttcgccttga
      481 ccagcgaggc gaatttgttg acctgtttcc acaccagcag ggattttcac atgtacgcta
      541 tgagcttgtt tctcatgacc tgttccatga caggttgtac atggatattt gatttctttt
      601 cctcgaccgt gacagacatc acaggttact tggcgacgca tcataccaag aggagtctgc
      661 gtatcgacgt taatgacacc agcgccatga cagcgtccac aagtgactgg acttgtccct
      721 ggcttagcac cagagccatt acatgtacga cagccagctt cacgatgata cttaacttcc
      781 ttctcagttc cgaagatagc ttcttcaaag gtcaaattga cacgatactg gagatcatct
      841 ccttggcgag gagcgtttgg attgcgcgaa gaaccgcctc cgccgaagaa acttgagaaa
      901 atatcctcaa aaccaccgaa gccacctgcc ccattgaaac caccgaaacc accagctcca
      961 ccaaaaccac cattggcgcc tgcagcacca tactggtcat aggcagcacg tttttggtcg
     1021 tcactcaaag tctcataggc ttcttgaact tccttgtact tgtcctcagc accaggctcc
     1081 ttgttgatat ctgggtgata ttttttggaa agcttacgat aagccttttt gatttcgtct
     1141 gccgaagcgt ttttggatac ccccagacga tcataaaatt cagtattgtt cataattcaa
     1201 gatacaaagg gcgtcaaacg gacacagcca tctaggagtt ttgacgacgg acgcttacgt
     1261 cctagaaaaa actatctttt tggcacagtc catagcccgt gttcagttac gaacaccctt
     1321 attcctttct attgatgttc tgaatcgaac caccatttag gtcgggttca attcctttct
     1381 tttatattta gtaagaaatt ctgaaacccg tgttcagtta cgaacactct ttgttccttt
     1441 ctattgatga gacaaaaccc aaacaaatga gattccgtcc ctttttatcg aaaaacagag
     1501 gctgggttgc aacctctgca aataagtaaa ttaactttat tttgatttta aatatcctat
     1561 aagtacagaa atatttatat atttttgtct cttcttagta tttgcctata taattccaat
     1621 tgatcataag aaatacaact actgtccaaa tcataccaat tatgaacggt attacaaatt
     1681 tatatgtttg tatttctaat gatatcatag ctggtaccat cgccgataca aatgcagaca
     1741 acaatactga ggtaacaaaa ttccttaccg cttcatcatt tttgatacaa ctatcatgtt
     1801 cagctaatat aatttctcta tatctagcta aatattctat tggaatatta tcaataaaat
     1861 cttttgatgt tctatagtta tcagcttgat tacaaaaatc attataaact tttcgtgtat
     1921 tttttagata ctcttcatcc aatacactca tcttactttt ccgtaaactc tccgtctacg
     1981 acgtcatcgc ctgcgttccc tgttgcttgt gcgccttctg ctccttcttg agcttgttgc
     2041 gctgctgcgg cttgttcgta gagtttaaca gcaagtcctt gagctttttc gttcaatgct
     2101 tcaagttttg ttttcatgtc gtccaagttg ttgtcttctt gagctttctt aaggtcatca
     2161 agggcagctt gggcagcgtc acgttctgcg tcgaagcctt taccttcagt ttccttgatt
     2221 gtcttttcag tcgcaaagat tgcttggtct acttcattac gaaggtctac ttcttcttta
     2281 cgtttcttat cggcttcagc gtttgcttct gcatctttca tcatgcggtc gatttcttcg
     2341 tcagtcaaac ctgagttcga ttggatgaca atagtttgtt ctttttgagt tccaaggtct
     2401 ttggccttaa cagacacgat accgttcttg tcgatgtcaa atgttacttc gatttgagga
     2461 attccacgag gtgcagctgg gatatcagtc aattggaagc gtccaagagt cttgttatct
     2521 gctgccattg ggcgttcacc ttgaagaacg tggatatcaa cggctggttg gttgtctgct
     2581 gctgttgaga agacttgtga tttagatgtt gggattgtag tgttgcgatc gataagtttt
     2641 gtaaatactc cacccattgt ttcgatacca agtgacaatg gcgttacatc aagaaggaca
     2701 acgtccttga catcaccagt aatcacacca ccttggatag ccgcacccat agcaactact
     2761 tcatcagggt ttactgattt gtttggttct ttaccagttt cagctttaac agcttcaaca
     2821 acggcaggga tacgagttga accaccaaca aggataactt cgtcgatttc tgacaagctc
     2881 aaacctgcat ctgaaagggc ttgacgaact ggaacttttg tacgttcaac aaggtcacga
     2941 gtcaaatcgt caaatttcgc acgagtcaaa gtcatttcca agtgaagagg tccagcctca
     3001 cctgcagtga taaatggcaa gctgatttgt gttgaagtta caccagaaag gtctttcttc
     3061 gctttttcag ccgcatcttt caaacgttgc attgccatct tgtcagtaga caagtcgata
     3121 ccgttttctt tcttgaattc tgctaccaag tggtcaatga ttttttggtc aaagtcgtca
     3181 ccaccaagtt tgttgtcccc tgcagttgac aatacgtcga agacaccgtc acccaattca
     3241 aggatagaga cgtcgaatgt accaccacca aggtcaaata ccaagatttt ttcttctttg
     3301 tcagtcttgt ccaaaccata agcaagagct gctgcagttg gttcgttaac aatacgttct
     3361 acttcaagac cagcaatttt accagcgtct tttgttgctt gacgttgagc gtcgttgaag
     3421 taagccggaa ctgtgataac agctttggtt actttctcac caaggtagtc ttcagcgtag
     3481 cctttcaagt attgaaggat catagctgag atttcttgtg gagtgtattc ttttccattt
     3541 gcagaaactt tttcagaagt tcccatctta gatttgatag agataactgt atctgggttt
     3601 gtaactgctt gacgttttgc agcatcacca acgatgattt ctccgttttt gaatgagact
     3661 acagatggag ttgtgcggtt tccttctggg tttgcgatga ttttgctttc agttccttca
     3721 agaactgcaa ctgctgagtt tgttgtacct aagtcaatac cgataatttt agacatgtgt
     3781 ttttctcctt gttagttaat tttctatttt tctttttgat actcttctta agtggcgacg
     3841 ccgtcagagc ttgacttcgt cagtctcttt tactaaactt tgagcctaag gtctcaaaat
     3901 ttgcgcaaat agcgccacgg cgaagagtat cgtctttggt tcgcttcgct cactattaca
     3961 aagcaaaaca tattttatct ttcttcatag tttattgtcg tttcggacaa gttttctatt
     4021 atgtaaattg cgacacgagg agtcgaaatc gattttattt cgacgacgag ttagtaagga
     4081 agctaggcaa acgccatagc aattgccgtt ttctgacgag ttgctttagc taccgtcaga
     4141 attgccgaat cgaacacgcc ctaagctctg agtaaaaaag atagattttc ttgtgttcat
     4201 cgaacacttc gtcaatctcc tatttttact gcgagctttt tacgggcttt gtatcttagt
     4261 tatacaccac taccattgct gggcgtagga tgcggtcatg gagtttgtag cctttttgaa
     4321 agacttgggc gatggtatct actgggtgtt catcgtctgc tgggagagtt tggatggcca
     4381 tatggtagtt atggtcaaat tcgccatctg ctgcgatttc ttcaattcct tcttctttca
     4441 aagcgtgaat caagctttct tgcaccatcc ccaagccctt cttcacatca tctgtcaaac
     4501 cttcaactgc aagtgcacgc tcaaggttgt caagagatgg taagattgct tttgccaagt
     4561 cctggctacg ataacgttgc aagttttgac gttcttcatt ggcacggcgt tggatatttt
     4621 gcatttctgc atgagcgcga agatatttgt tttcgaactc atctgcacgt tcatttgcca
     4681 agtccaactc agacttttca ggagttgttt cttcagctgt ttccacaact tcctcttctt
     4741 gaacttcttc tacttcttca ttttttatat cttgggccat gttcgcctcc tttaatgatt
     4801 tcaatcttaa tgtacttcgt aatgattact gctgaggtag cggtaaaaat ctgtcaactt
     4861 catggtcaaa acacggttga ccacattgat ttgattgatt agctgttggt aatccagatt
     4921 aactggaccg ataatggcta gaattccaac tccccgataa ggaatgagga acttactact
     4981 aatcaccgct aggtcagcta aacaggactc ttgaccgtct gcaacacgaa cattttgcat
     5041 ctgatcctca cgcaacccct cacgaatctc caaggccacc ttttgcggtt ggtcaaagaa
     5101 ctgataggct gctagattgg caaaattcaa gagattgacc ttgcccgcca tcacaatgtt
     5161 ttcgttgaac atttccttaa agatgtgttc aaagagatcg atgacattat ccgttgttgt
     5221 aaagtaacgc tggataatct gcggaatctc cgtccgaatc ttgtagtgaa tatctaaaac
     5281 ggtgtgaccg aggaaacgtt cctgaatgat gctcttcagt ttcagcaaat cctcctgcaa
     5341 gaagttcctt ggaatcagaa actgactagt aaccgttcgc gactcgtcta gggtaaatac
     5401 cgccaaggct gtatgttgcc ccaaaacaac gatatcaaag gctgtcaaac gttgcctgct
     5461 cggctcaaca tccagtgcca ctaccgtaca gccactcagg tctgttagca agttagcagc
     5521 ctcttgcaga atatcctcca atttgaagaa ttcctgatca aaggctttga caatctcata
     5581 tacctcattt tcagccagtc ggtcaaaatc cagtgagtgt ttcacatagt actgaaaacc
     5641 agcaacactt ggcatccgac cgcttgaagt atgagccttc tcaagcaacc cttgtttttc
     5701 tagttccgcc atgtcattac gaatggttgc actgctagag ttaatagact cttgcaaggc
     5761 ttttgatccg acaggttcgt gcgttttggt aaagatgtca ataatcagat ttaaaatatc
     5821 ctgctgacgc tctgtaacca tctcatcact cctctctgtc tgatcaatta gcactcaatg
     5881 catccaagtg ctaacttatg attctattat acacccttag aagagaatgt caagacaaaa
     5941 actcaaaaaa ttagcactct tttataaaga gtgctaaaaa tcaatctgaa gacctagaac
     6001 cttgctattc atctactcgg tatttccttt ttagtctgaa ataaccatga attagataag
     6061 aaatcagaaa agcatataaa acaaaaataa gaaagaaaga catagaaaga tcctctctaa
     6121 acaaactcat acaaacaaca agaccaccta agaaagtagc tatacaggaa cgaagtctag
     6181 atcgcataac ttcccatttg agccccttac tcatatagac ttgatcctct ggaagtaaat
     6241 cagaagacga tttacgaaga atcgaacaag aacctgctcc tatcaattcc caacctctat
     6301 ctctaaaatc ttgcagttca cgcttatgct ctttaagaaa tctagaatca tagatacgat
     6361 agataacatc gtccggttga ccttgctcaa aatagaacaa accaaaacga ctagttctat
     6421 acctccaacc tttcaaatgc atctcatgta aatattcttc tttcttgtcc aaatcaacaa
     6481 tggtgaaaat ccgaaattct actctgctat tcattgtctt accccaaaat tagaaaacat
     6541 gcctagcgtt atttattaga taattctttc cacttttgac tcaatctcca aaaaatataa
     6601 gaaatctgaa tcgcaaaaac tatcaataaa acccaatcta ttatgaaaat caaaaacact
     6661 tcccaactga aagaactacc tccagtgaca aactttgaga aaaacggtag tagagctaaa
     6721 aagagaagca aaataggaag catccgcatt gttaaaatcc ttttggcata aaaaaatctt
     6781 tatttaaacg aaaatattat ggcaaaattt acgccagttt ttgaacggct gatgtagata
     6841 ttttatactt tcaaaatgtt taaatgtgat tatttatttt tgaaaaatag ctcaccagcc
     6901 cgactgaaag tgcttataga atgataataa gtcgcctgcc gaaaacagcg aaaaatagca
     6961 gtgttatgcg gagataatct gacgcgatgc gaaagtatat tgcatactta ttttcaacaa
     7021 tttagcagag tatttttata agtgtgatat aatagaagta taatttgttc tgatagttta
     7081 ttttatggag aagtagattt ttagaatgcg gaggattcaa tatggttgag tttataaagt
     7141 ctaagaaaga aatgagtgag gaggatatta aagcaaattt catcactcct gctattgtat
     7201 ccaaaggatg gaaaaatggt gagcatatcg cttacgaaga atacttcact gatggtcgaa
     7261 ttgaagttag aggagataag gctcgtcgta aagaaggaaa aaaatcagac tattcactgt
     7321 attaccaatt tggaactcga attgcaattg ttgaggcaaa ggataataaa cacagcgttc
     7381 gagcaggatt acaacaagct attgaatatg gagagatttt agatgttcca tttgtttatt
     7441 cttcgaatgg tgatggcttt attgaacacg accgtatcac gagagaagaa cgtgagctgg
     7501 agttagacga attccctact cgtgaagaat tattttctcg tatgacgaag gaaaaaggat
     7561 tgacgtacga aattacagaa gctatctcaa ctccatacta tacagacgcc ttctcaatga
     7621 aaacgccacg ctattatcag caaatagcta tcaaccgtac tattgaaaca gttgccagag
     7681 gacaaaaacg agtaatgttt gtgatggcaa caggaacggg gaaaacgttc atggcttttc
     7741 aaattattca tcgccttcga aaagctggtt tggctaaacg agttttattc ttagcggata
     7801 gaaacatctt agtagaccaa acgatggctg aagactttaa gccattcgaa aaggtaatga
     7861 cgaaaattac accaaaactt ttgactgctc ctgaaaaatt aaattctttt gaaatttatc
     7921 tagggcttta tcagcaacta actggtgaag atggaactga aacacattat caaaaatttg
     7981 ataaagactt ctttgattta atcgtaattg atgaagcgca ccgtggttca gctaaggaaa
     8041 acagtaactg gcgtaagata attgattatt tcagttctgc gacacagatt gggatgaccg
     8101 ctactcctaa agaaaccaag aatgcttcca atacggaata ctttggtgag ccaatctata
     8161 cttatagttt aaaacaggga atcgaggatg gttttttggc tccatatcgt gttatgaggg
     8221 ttaatttaga tgtggatgtg gatggttatc gtccagaaac tggaaaagtt gatactaacg
     8281 gacaattaat agaagatagg tactacggca ggaaagattt tgataaaacc attgtcattg
     8341 atgatagaac gcaaagagtt gccaagtttg tttctgatta tatgaagcaa aacaatgcac
     8401 gatttgataa aacaattgtt ttttgtgttg atattgacca tgccgagcga atgcgtgctg
     8461 cacttgtaaa agagaatcta gacttagtcc aagaagacta tcgttatgtc atgcaagtaa
     8521 ctggtgacaa cgctgaagga aaagctcaac tggataactt tatggatgtc aattctaatt
     8581 ttcccgctat ggtaacaacg tctaaattat taacgacagg agttaatgct aaaacatgtc
     8641 gtttgattgt tttagactct aatatccaat ccataactga atttaaacaa attattggtc
     8701 gtggcacacg tctttatcct caaaagggga aagaattttt tacgattatt gattttcgaa
     8761 atgttaccaa tttgtttgct gaccctgatt ttgatggtga gccagtgaag gtgctggaaa
     8821 caggtgcgaa aacagtcagt ggttccacgc ccggtttcgt agatgaggaa ggtgacccag
     8881 tagaaaaata tatcgttaca gacaagcagg ttaccattct taattctact gttcaagtat
     8941 tggatgaaaa cgggaaactg attaccgaaa gcctgaccga ctacactcgg aagaatatct
     9001 taggtagcta cgccactttg aacgatttta tcacagtttg gcatacggcg aataaaaaga
     9061 agcttatctt agacgaactt tataaaaaag gagtttatct agatgctatt cgagagtcgg
     9121 agggaatatc agaacaagaa atcgatgatt ttgatttact cctaaaactt gcctatggtc
     9181 aaaaagaatt aaccaaaacg gaacgtatca ataaactcaa acaaagcgga tatttatata
     9241 aatatagtga ggaagcgcgt gctgttttgg aaattttact gaacaaatac atggataaag
     9301 gtattggaga actcgaaagc attgaaacat taaaacttcc agaatttcag atatatggtg
     9361 gaaccttcaa aatcatcaat acttattttg gagataaaaa acgatattta caagcaatta
     9421 aagaattgga gcaagagcta tttacagtag cttaatgaaa ggaaagtatg tcaattacat
     9481 catttgtaaa aagaattcaa gatatcactc gaaacgatgc tggtgttaat ggtgatgctc
     9541 aacgtattga gcaaatgtct tggttattat tcttaaaaat ttatgatagc cgtgaaatgg
     9601 tttgggaatt agaagaagac gagtatgagt caattatccc agaggaatta aaatggcgaa
     9661 attgggctca tgctcaaaat ggggaacggg tattgacagg cgatgaatta cttgattttg
     9721 tcaataacaa gttattcaaa gagttgaaag agcttgaaat aacttcaaat atgcctattc
     9781 gaaaaacgat tgttaaatca gcttttgaag atgcgaacaa ctatatgaaa aatggcgtct
     9841 tgttacgcca agtcatcaat gttattgatg aagttgattt caatagccct gaagatcgtc
     9901 attcgtttaa tgatatttac gaaaaaattc ttaaagatat tcaaaatgct gggaactcag
     9961 gagaatttta tacgccacgt gcagcgactg attttattgc cgaagttctt gacccaaaac
    10021 ttggagaatc aatggcagac cttgcttgcg gaacaggagg cttcttgact tcgactctga
    10081 accgtttaag tagtcaacgt aaaactagtg aagataccaa aaaatataat acagctgttt
    10141 ttggtattga aaagaaagca tttcctcatc ttttagcagt tacaaatctg tttcttcacg
    10201 aaattgatga ccctaaaatt gttcatggaa atactttgga gaaaaatgtt cgtgaatata
    10261 cggatgatga aaaatttgac attattatga tgaatccacc ttttggaggg tcagaattag
    10321 aaacaataaa aaataacttt ccagcagaat tacggagttc tgaaacagct gatttattta
    10381 tggctgtcat tatgtatcgt ttgaaagaaa atggtcgtgt tggagttatt ttacctgatg
    10441 gttttctatt tggtgaaggt gtaaaaactc gcttgaaaca aaaactggta gatgagttca
    10501 acttacatac gattattagg ttgcctcata gtgtctttgc accgtataca ggaatccata
    10561 cgaacattct tttctttgat aaaacaaaga aaacagaaga aacttggttt tatcgtttag
    10621 atatgccaga tggttataaa aatttctcga aaactaagcc gatgaagtca gaacacttca
    10681 atcctgttcg tgactggtgg gaaaatcgtg aagagattct ggaaggtaag ttctacaaat
    10741 ctaaatcatt tacacctagt gaattggctg agttgaatta taatttagac cagtgtggct
    10801 ttccaaaaga ggaagaggaa atcttaaatc cctttgagtt gattcagaat tatcaagcgg
    10861 aaagagcaac tttaaatcat aagattgata atgtattagc tgatattttg cagttgttgg
    10921 aggacaaata atgacaccag aacaacttaa agcaagtatt ctccaaagag cgatggaagg
    10981 gaaattagtg ccgcaaaatc ccaatgacga acctgcaagt gaattattaa agagaattaa
    11041 agctgaaaaa gaaaaactta tcagtgaagg aaaaatcaaa cgagataaaa aggaaactga
    11101 gatatttcgt ggtgatgatg ggaaacatta tgggaagttt gctgatggaa gcactcaaga
    11161 aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggtttt ctacattggt
    11221 tgaaattgtc agaggtggct ctccacgacc aatcaaagat tatcttactt ctgaagtaga
    11281 tggaataaat tggataaaaa taggtgatac tgaaaagggt gaaaagtata taaataatgt
    11341 taaagaaaaa atcaaaaaat cagggcttaa caaaactaga tttgtaaaaa aaggtacatt
    11401 tttgttaact aattctatga gttttggtag accttatatt ttgaatgttg atggtgcaat
    11461 acacgatgga tggttggcta tttcgaacta tgaaaactca ttaaataaag attacctatt
    11521 ctatattctt tcatcaaatg tagtttattc tcaatttcta tctctaatta gtggagctgt
    11581 tgtgaaaaac ttgaatagtg ataaagttgc ttctattctt atccctctcc ctccactatc
    11641 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
    11701 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
    11761 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
    11821 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
    11881 taaaaagaaa gatttggaca tttctattgt ttcccaagga gatgataact cttattatga
    11941 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
    12001 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
    12061 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
    12121 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
    12181 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
    12241 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
    12301 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
    12361 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
    12421 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
    12481 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
    12541 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
    12601 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
    12661 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
    12721 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
    12781 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
    12841 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
    12901 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
    12961 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
    13021 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
    13081 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
    13141 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
    13201 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
    13261 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
    13321 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
    13381 ctgctatttt tgtgattatg gctcttatta tgggaataaa gacgaaacaa cctcttatcc
    13441 tatatatgaa atcccagaag catggagata tattaaattt gctagcctag ttaacttcag
    13501 aataggaaaa actcctccac gcagtgaagc tactttttgg ggaactgaaa taccctgggt
    13561 atctatatca gatatgccta tatctggtta tgtaactaat acgagagaat ctatttctaa
    13621 attagcatta aaatcaaaga aaatagacat ttcacctaaa ggaactttat taatgagctt
    13681 taaattatct attggaaaag ttgccatatt ggatattcct gccactcata atgaagccat
    13741 tatatcgata ttcccctatg ctaataaaga aaatattatc agagattact taatgatatt
    13801 tttgccactt atctctactt taggtgattc aaaagatgct atcaaaggga aaacattaaa
    13861 tagtaccagt atctccgaat tattaatccc tatttctaat catgaagaga tgaaaagaat
    13921 catttccaaa gttgatttac tttttcaaaa agtttctcaa ctttttgagt aataagttcc
    13981 tgttcctcaa aaggagctaa cggaattaat agctcgctta gtgtagtttt aggaatatta
    14041 tataaagctt gacctgatag tttagttatt gctttcaatt gtttataaaa taacggagag
    14101 gacaagttaa ataatagaaa ttttgaaata atctctgaac tttcgaatgg tgttaattgg
    14161 aaaatgaatc caccagccac aacaccatca tagtctttat cgattcttgc aaactttcca
    14221 atatgttcta aagaggttga tacaggtgtt attagctgat tatgttttaa ataaacttgc
    14281 tcagaggaga tgaattgtgt atcaatgtag taatcattat ccaacagaga aaattctaaa
    14341 ggcttaatat taccaccacg tataattcta atacctttat tattaatgct taaatcgccc
    14401 ttcttgtaag aaagacctgt atttattgaa aaaatatctt ttatttttat aacaacccaa
    14461 ttcataggt
//
LOCUS       DBEJJE010000048        14415 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEJJE010000048 DBEJJE010000000
VERSION     DBEJJE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.48"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(133..969)
                     /locus_tag="ACL3F5_001660"
     CDS             complement(133..969)
                     /locus_tag="ACL3F5_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515426.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(982..1611)
                     /locus_tag="ACL3F5_001661"
     CDS             complement(982..1611)
                     /locus_tag="ACL3F5_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0515427.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(1621..2262)
                     /locus_tag="ACL3F5_001662"
     CDS             complement(1621..2262)
                     /locus_tag="ACL3F5_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0515428.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(2408..3637)
                     /locus_tag="ACL3F5_001663"
     CDS             complement(2408..3637)
                     /locus_tag="ACL3F5_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0515429.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILELQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEYYQELSGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(3627..4793)
                     /locus_tag="ACL3F5_001664"
     CDS             complement(3627..4793)
                     /locus_tag="ACL3F5_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0515430.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            4937..5950
                     /locus_tag="ACL3F5_001665"
     CDS             4937..5950
                     /locus_tag="ACL3F5_001665"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0515431.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(5995..6414)
                     /locus_tag="ACL3F5_001666"
     CDS             complement(5995..6414)
                     /locus_tag="ACL3F5_001666"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0515432.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(6425..7831)
                     /gene="atpD"
                     /locus_tag="ACL3F5_001667"
     CDS             complement(6425..7831)
                     /gene="atpD"
                     /locus_tag="ACL3F5_001667"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0515433.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(7917..8795)
                     /locus_tag="ACL3F5_001668"
     CDS             complement(7917..8795)
                     /locus_tag="ACL3F5_001668"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0515434.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(8811..10316)
                     /gene="atpA"
                     /locus_tag="ACL3F5_001669"
     CDS             complement(8811..10316)
                     /gene="atpA"
                     /locus_tag="ACL3F5_001669"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0515435.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFDSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10331..10867)
                     /locus_tag="ACL3F5_001670"
     CDS             complement(10331..10867)
                     /locus_tag="ACL3F5_001670"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0515436.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(10867..11361)
                     /gene="atpF"
                     /locus_tag="ACL3F5_001671"
     CDS             complement(10867..11361)
                     /gene="atpF"
                     /locus_tag="ACL3F5_001671"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0515437.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(11375..12091)
                     /gene="atpB"
                     /locus_tag="ACL3F5_001672"
     CDS             complement(11375..12091)
                     /gene="atpB"
                     /locus_tag="ACL3F5_001672"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0515438.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12126..12326)
                     /locus_tag="ACL3F5_001673"
     CDS             complement(12126..12326)
                     /locus_tag="ACL3F5_001673"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0515439.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(12401..13336)
                     /locus_tag="ACL3F5_001674"
                     /pseudo
     CDS             complement(12401..13336)
                     /locus_tag="ACL3F5_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(13822..14220)
                     /locus_tag="ACL3F5_001675"
     CDS             complement(13822..14220)
                     /locus_tag="ACL3F5_001675"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515440.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT         4362 a         3166 c         2565 g         4322 t
ORIGIN      
        1 acaatgtttt agaaatcaca gtgggctatt ccatattcaa ttatccatat tcaatcgcta
       61 ttatcgtttt cctagattac aaaaaaaact acgttttgct aatcaaaacg cagtttcagc
      121 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
      181 tttttggctg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
      241 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
      301 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aatagtttgc
      361 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
      421 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
      481 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
      541 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
      601 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
      661 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
      721 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
      781 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
      841 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
      901 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
      961 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
     1021 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
     1081 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
     1141 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
     1201 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
     1261 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
     1321 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
     1381 tcccagtaga ttgcgcttct gcaattcatc cagctctaaa ggttgtccat tataaaagat
     1441 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
     1501 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaattaga
     1561 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tggcagcctc
     1621 ctatctataa taactatact tcttctcaac ttttttggaa ataattgtca caatcccaat
     1681 caaaatcaaa taaatggctc ctgccaagaa cataggaact agactagcat cgcggttagc
     1741 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
     1801 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
     1861 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cggcctcata
     1921 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
     1981 gttgagaaca aaggcaataa tagctgcagg aaggcggtct aaacgaatcc caatacttgg
     2041 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
     2101 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
     2161 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
     2221 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
     2281 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
     2341 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
     2401 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
     2461 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
     2521 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgacaactct tgataatact
     2581 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
     2641 aaagattttc tggctcctca ctctgcaatt ctagaatatc ctcataacgc tcctgctcca
     2701 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
     2761 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
     2821 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
     2881 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
     2941 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
     3001 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
     3061 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
     3121 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
     3181 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
     3241 tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg
     3301 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
     3361 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
     3421 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
     3481 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaattca tacagaagat
     3541 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
     3601 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
     3661 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
     3721 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
     3781 aacaaaacaa agagaacatt aatagggtgg atgtttaatt gacttcccaa aatcaatgga
     3841 gagacaaaac ggccttcaat agtttgttct acgataaaga caatcactac tttcaaaagc
     3901 atgactggac cagcaatcaa acccaatact agagcaggaa gcatggctag aaagctacca
     3961 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
     4021 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
     4081 cctcgaacat agttggacaa ctgttgattc acatctgata aaacttgtcc aacaggttcc
     4141 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
     4201 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agccccgcta
     4261 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
     4321 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
     4381 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
     4441 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
     4501 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
     4561 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
     4621 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
     4681 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
     4741 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
     4801 tcctttctat tgttctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
     4861 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
     4921 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
     4981 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
     5041 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
     5101 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
     5161 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
     5221 tttggtttac gcagctaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
     5281 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
     5341 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
     5401 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
     5461 ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc ataaccacta
     5521 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
     5581 cgttggcgaa tttgaacgta tgcaggtcat ttcaacttta ccggaagctt acgaaggctt
     5641 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
     5701 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
     5761 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacacccg accaaaaatt
     5821 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
     5881 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
     5941 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
     6001 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
     6061 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
     6121 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
     6181 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
     6241 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
     6301 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
     6361 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccatagatca
     6421 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
     6481 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
     6541 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
     6601 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
     6661 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
     6721 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
     6781 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
     6841 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
     6901 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
     6961 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
     7021 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
     7081 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
     7141 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
     7201 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
     7261 cacgagtacg ttccccaaca ccagcaaata ctgaaatacc accgtgctct tgggcaatgt
     7321 tgtgaatcaa ttcttggatt aagacagttt taccaactcc ggcaccaccg aaaagtccaa
     7381 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
     7441 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
     7501 ctgcgtcttc tgtaaaagga gcttccaagt caatggtatc tcccaaaacg ttgaagacac
     7561 gtcccaaagt ttctttacct actggtacag agattggacg acctgtgtcc aatacttcca
     7621 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
     7681 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
     7741 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
     7801 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
     7861 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
     7921 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
     7981 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
     8041 tgcatggctg tcatgcccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
     8101 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
     8161 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
     8221 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
     8281 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
     8341 acttgatcaa agctaggttg gtctgacaag ccacgtaatt cataaagtgg ttgaataccg
     8401 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
     8461 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
     8521 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
     8581 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
     8641 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
     8701 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
     8761 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
     8821 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
     8881 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggcatggaac
     8941 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
     9001 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
     9061 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
     9121 tcaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
     9181 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
     9241 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
     9301 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
     9361 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
     9421 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
     9481 cgacgaagca agagcgacag ttcacgataa gctaccgctt gttttgatag atcatcgtat
     9541 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagcataa
     9601 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
     9661 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
     9721 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
     9781 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
     9841 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
     9901 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
     9961 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    10021 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    10081 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    10141 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc gtgagcacgc
    10201 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    10261 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    10321 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    10381 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    10441 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    10501 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    10561 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    10621 aggccagaac ctggataaag ttttgtaata aaggtgacac agaatcttgg aaaaaagcaa
    10681 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    10741 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    10801 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    10861 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    10921 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    10981 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    11041 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    11101 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    11161 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    11221 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    11281 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    11341 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    11401 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    11461 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    11521 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    11581 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    11641 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    11701 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    11761 gcgaactcca ccagttagtc ccatcgatcg tttgaatctt tgtcattaag ccaaggttat
    11821 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    11881 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    11941 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    12001 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    12061 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    12121 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    12181 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    12241 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    12301 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    12361 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    12421 aaattatttc cattttgcta aatttcaagt tcaagttagc catccagaag tcttctctgg
    12481 gtgacttgta atccaagcat tttttaggat agttgttaat ccacttttcg atgaatgcga
    12541 cttctttggg agtcattttc ttggttccct taggtaacca tctacgaatg agcctgttgt
    12601 gattctcatt agttcccctt tcccaagagg catagggatg tgcataataa atgtgctcct
    12661 cagaaaatac attagacaag cgattgaatt ccgttccatt atctgccgtg atggaaagaa
    12721 tcttgtgttg ttttaagatg agttttagag cctgattgac cacctcagca cttttatttg
    12781 gaatcaatcg gatgatctga tgtctactct ttcgatccgt caagacaagc aagcagtagt
    12841 ttttcgatct cgtaagtaga accgtatcaa tctcataatg cccattctcc aagcgaagat
    12901 tgatagcttc aggccgctgt gcgatggatt gaccagcagg tttaaagttg gtgctagcct
    12961 gtttcttaag cacttttcct tttctagggt aaagcagatc ctgcttgctt aaccccaatt
    13021 ttccatgatg aatccaatag taaatggttg aaattcccac gttaacccct ttagccatca
    13081 ccatcatttc aggcgaaaat ttttggttat gatagtggag aatcttttcc tttagttcct
    13141 tggtcaagct tgatttcttg accgagcgct tgcgattgtt ttcataagac tgttgagcat
    13201 agtcggcaga ataaacctct ttgaagcgcc cttttccaag acattttcgg actgtcctac
    13261 gcttgatttt agtgtggata gtttgaggag cttttccaag cagagaggta atttctctat
    13321 ttgatttccc tttgttcgcc ttttgtagta taatggtttt gcatctctgt gcctttcttg
    13381 tgtttgtggt tgaacaacaa gtataacaca gaggtgtttt cttatgccta caagagcttt
    13441 cattatttcc attttctttc ggatttcact ctattctgaa aaacttgtgt atatttactg
    13501 aagctagcaa gtcttacctg taaatttaat gaaagcaaca caaaatccga gaggggaatc
    13561 tcggattaat gtcaatttaa aaagatagag agtttttagt ttaaataaat tgttttaaaa
    13621 tatcaacaac atcacttctt ttcttaacct gataagcctt gattcctaat tttggagcta
    13681 cgattatatt gtcctcaata tcgtctagaa agacacaatt tctaggttat aactggtatt
    13741 tatcgatagt tactcatata catcagtcca cctccatact tatgtgcgag cctctctttg
    13801 tattatacct ccatactcac cttacagatt cttttggtaa taatatcttt gcctaatgta
    13861 gagatagtct tgcaaagaaa aaacttcctt gtagccatgt ttctgataaa agtccggtgc
    13921 ctggaactga taagtattga caaaggcaaa acaacaattt cgattcttag cttcactttc
    13981 tgcctgttgc aatagttttg aaccgattcc ttgccctcgc agttcctctt ttacaaacaa
    14041 atactcgatt tctagccaat ttccaaaagt ctctgctatc aaacccgcaa ggagattgcc
    14101 cttttcatct tcgacataaa gattaagtgg ctcactttca gcctcttccc tttttgaacg
    14161 gttataaaca cgaatcagat tccctatttc ttgcgattta tgtgattcct tattttccaa
    14221 tctaaagtat aatgaaatga aataaaacat gcgcaaatcg attaaggaat ttaatctaat
    14281 ttctaataat gtcttagaaa tcaaagttta ctattttaac ttcaatgcac tatacatcta
    14341 atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg
    14401 ttttgaggtt gtaga
//
LOCUS       DBEJJE010000049        14315 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEJJE010000049 DBEJJE010000000
VERSION     DBEJJE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.49"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..126
                     /locus_tag="ACL3F5_001676"
     CDS             <1..126
                     /locus_tag="ACL3F5_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0515441.1"
                     /translation="ENIFAKVKTFKMISTTYRNHRKRFGLRMNLIAGIINHELEF"
     gene            complement(441..2132)
                     /gene="argS"
                     /locus_tag="ACL3F5_001677"
     CDS             complement(441..2132)
                     /gene="argS"
                     /locus_tag="ACL3F5_001677"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0515442.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2268..2714
                     /gene="argR"
                     /locus_tag="ACL3F5_001678"
     CDS             2268..2714
                     /gene="argR"
                     /locus_tag="ACL3F5_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0515443.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2765..5299
                     /gene="mutS"
                     /locus_tag="ACL3F5_001679"
     CDS             2765..5299
                     /gene="mutS"
                     /locus_tag="ACL3F5_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0515444.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQTLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5446..7140
                     /gene="patA"
                     /locus_tag="ACL3F5_001680"
     CDS             5446..7140
                     /gene="patA"
                     /locus_tag="ACL3F5_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0515445.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTDV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     NQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7290..7739)
                     /locus_tag="ACL3F5_001681"
                     /pseudo
     CDS             complement(7290..7739)
                     /locus_tag="ACL3F5_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7931..9697
                     /gene="patB"
                     /locus_tag="ACL3F5_001682"
     CDS             7931..9697
                     /gene="patB"
                     /locus_tag="ACL3F5_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0515446.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSAGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9836..10525
                     /locus_tag="ACL3F5_001683"
     CDS             9836..10525
                     /locus_tag="ACL3F5_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0515447.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10529..10708
                     /locus_tag="ACL3F5_001684"
     CDS             10529..10708
                     /locus_tag="ACL3F5_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515448.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10695..12044
                     /locus_tag="ACL3F5_001685"
     CDS             10695..12044
                     /locus_tag="ACL3F5_001685"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0515449.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12168..13628
                     /gene="gltX"
                     /locus_tag="ACL3F5_001686"
     CDS             12168..13628
                     /gene="gltX"
                     /locus_tag="ACL3F5_001686"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0515450.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQIKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13642..14076
                     /locus_tag="ACL3F5_001687"
     CDS             13642..14076
                     /locus_tag="ACL3F5_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0515451.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
     gene            14200..14271
                     /locus_tag="ACL3F5_001688"
     tRNA            14200..14271
                     /locus_tag="ACL3F5_001688"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14233..14235,aa:Glu,seq:ttc)
BASE COUNT         4210 a         2757 c         3215 g         4133 t
ORIGIN      
        1 gagaacatct ttgccaaagt aaaaacgttt aaaatgattt caacaaccta tcgaaatcat
       61 cgtaaacgct tcggattacg aatgaatttg attgctggta ttatcaatca tgaactagaa
      121 ttctagtttt gcaggaagtc tattatttgg ttaggtgaat tagtgaagcg tttaggcaag
      181 tgtctctggt tacgacgtca tggcctctaa atcgattata tttaggggtc atgactagtg
      241 aagcagttag ctagttcgca tataagcggc tagcgtctaa caattaggaa ctttagttcc
      301 aataacttta agattacgac gttttaggac ataaatcgat catatttatg tcctaaaact
      361 agtgaagcgc ctagccaaag tccgaatagg atttggcgtt agttacttag attgctttgc
      421 aatcaagtaa ctttggcgat ttacatcttc tctggcgctt ctactccaag caagcgaagg
      481 gcttctttga gaacgactgc ggttgcgtag ctgagggcta gacggctgtc gcgttctggg
      541 ctttcatcca agatacgtgt atgtgcatag tatttgttaa aggattgagc caggctaatt
      601 gcaaatttag caatgataga aggttcaaag ttatctgccg cacggttgat aatacgtggg
      661 aagtcttgaa tgagtttaat gatttcccag ctttcagtat cattcaagct atagttgcca
      721 gctgtttctg gtttgaaatc ggctttgcgt aggatagatt ggatacgagc gtaggcatat
      781 tgaacgtaag gtccagtttc accctcgaag gataccatag cttctaggtc gaagtcgtat
      841 ccatttgtac ggtcggtttt gaggtcatag aatttaatgg ctccaacccc aacagcatgt
      901 gctacttggt ctttgttttc tagttcagga tttttagcct cgatttggac cttggcacgg
      961 ctaacagcct ctgcaacagt aggctctagc aagatgacat tccctttacg agtagagagc
     1021 ttcttccctt cttttgtaac cagaccaaaa ggaacgtggg taatgtcgtc actccaatcg
     1081 tagcccatct cttgcaagac agctttgagc tgtttaaagt gggcagattg ttcttgacca
     1141 acgacataga tagatttagc aaattggtat tcgtttttac ggtagagggc tgcagccaag
     1201 tcacgtgtga tatagagagt tgcaccatca gacttcttga tgagggctgg atgttcaatt
     1261 ccgtatttct caagattgac aacttgggca ccttctgatt caagaagtag tcctttttca
     1321 gaaagaatgt ctacaactgc atccatctta tcattgtaga aggcttctcc gttatagctg
     1381 tcaaattcaa ccttcaattc attgtaaagg cggttaaatt ccactaaact ttcatcgcgg
     1441 aaccattgcc aaagagcgag agcttcctca tctccatttt caagtttacg gaaccattcg
     1501 cgcgcttctt catccaagct agggtcattt tcagcttcag cgttgatgcg gacatagagt
     1561 ttaaggagtt catcgattgg atgagctttt acagcttctt cgtcgcccca ttttttgtag
     1621 gcaacaatca acatcccaaa ttgtttaccc cagtctccca aatggttgac cttgaccgtt
     1681 tgataaccga ttttttggaa aatatgtgac aagctatctc cgataacagt tgaacgcagg
     1741 tggccaatag aaaatggttt agcgatattc ggactagaca tgtcgataac aacattttct
     1801 tgtttgccaa tattttggtc agcatagtgt tctttttcag tggtaacagc ttgcaatact
     1861 tgagcagaaa tggcagattt atcaaggaaa aagttaacgt aaggtcctgt tgcgacaact
     1921 ttttcaaagg cttggctgtt cattttttca gccagttcag ccgcaatcat ttgtggtgct
     1981 ttacgttcga cttttgcaag agaaaaagca gggaaagcaa tgtctcccat ttctgagttt
     2041 ttaggggttt ccagtaactt taaaatagcc tcttggtcca ggctatcaat gatgctagat
     2101 aattcgctag caatcaattc ttttgtattc attaagagct cctttttgga cttttctact
     2161 attttatcac aattttaaag aaagaagaaa aaatttttga aatctcctgt ttttttggta
     2221 taatatggtt ataaatatag ttataaatat gcacgcaaga ggattttatg agaaaaagag
     2281 atcgtcatca gttaataaaa aaaatgatta ctgaggagaa attaagtaca caaaaagaaa
     2341 ttcaagatcg gttggaggcg cacaatgttt gtgtgacgca gacaaccttg tctcgtgatt
     2401 tgcgcgaaat cggcttgacc aaggtcaaga aaaatgatat ggtgtattat gtactagtaa
     2461 atgagacaga aaagattgat ttggtggaat ttttgtctca tcatttagaa ggtgttgcaa
     2521 gagcagagtt taccttggtg cttcatacca aattgggaga agcctctgtt ttggcaaata
     2581 ttgtagatgt aaataaggat gaatggattt taggaacagt tgctggtgcc aataccttat
     2641 tggttatttg tcgagatcag cacgttgcca aactcatgga agatcgtttg ctagatttga
     2701 tgaaagataa gtaaggtctt gggagttgct ctcaagactt atttttgaaa aggagagaca
     2761 gaaaatggcg atagaaaagc tatcacccgg catgcaacag tatgtggata ttaaaaagca
     2821 atatccagat gcttttttac tctttcggat gggtgatttt tatgaattat tttatgagga
     2881 tgcggtcaat gctgcgcaga ttctggaaat ttccttaacg agtcgcaaca agaatgccga
     2941 caatccgatc cctatggcgg gtgttcccta tcattctgcc caacagtata tcgatgtctt
     3001 gattgagcag ggttataagg tggctatcgc agagcagatg gaagatccta aacaagcagt
     3061 tggggttgtt aaacgagagg ttgttcaggt cattacgcca gggacagtgg tcgatagcag
     3121 taagccggac agtcagaata attttttggt ttccatagac cgcgaaggca atcaatttgg
     3181 cctagcttat atggatttgg tgacgggtga cttttatgtg acaggtcttt tggatttcac
     3241 gctggtttgt ggggaaatcc gtaacctcaa ggctcgagaa gtggtgttgg gttatgactt
     3301 gtctgaggaa gaagaacaaa tcctcagccg ccagatgaat ctggtactct cttatgaaaa
     3361 agaaagcttt gaagaccttc atttattgga tttgcgattg gcaacggtgg agcaaacggc
     3421 atctagtaag ctgctccagt atgttcatcg gactcagatg agggaattga accacctcaa
     3481 acctgttatc cgctacgaaa ttaaggattt cttgcagatg gattatgcga ccaaggctag
     3541 tctggatttg gttgagaatg ctcgctcagg taagaaacaa ggcagtcttt tctggctttt
     3601 ggatgaaacc aaaacggcta tggggatgcg tctcttgcgt tcttggattc atcgcccctt
     3661 gattgataag gaacgaatcg tccaacgtca agaagtagtg caggtctttc tcgaccattt
     3721 ctttgagcgt agtgacttga cagacagtct caagggtgtt tatgacattg agcgcttggc
     3781 tagtcgtgtt tcttttggca aaaccaatcc aaaggatctc ttgcagttgg cgactacctt
     3841 gtctagtgtg ccacggattc gtgcgatttt agaagggatg gagcaaccta ctctagccta
     3901 tctcatcgca caactggatg caatccctga gttggagagt ttgattagcg cagcgattgc
     3961 tcctgaagct cctcatgtga ttacagatgg gggaattatc cggactggat ttgatgagac
     4021 tttagacaag tatcgttgcg ttctcagaga agggactagc tggattgctg agattgaggc
     4081 taaggagcga gaaaactctg gtatcagcac gctcaagatt gactacaata aaaaggatgg
     4141 ctactatttt catgtgacca attcgcaact aggaaatgtg ccagcccact tttttcgcaa
     4201 ggcgacgctg aaaaactcag aacgctttgg aaccgaagaa ttagcccgta tcgagggaga
     4261 tatgcttgag gcgcgtgaga agtcagccaa cctcgaatac gaaatattta tgcgcattcg
     4321 tgaagaggtc ggcaagtaca tccagcgttt acaaactcta gcccaaggaa ttgcgacggt
     4381 tgatgtctta cagagtctgg cggttgtggc tgaaacccag catttgattc gacctgagtt
     4441 tggtgacgat tcacaaattg atatccggaa agggcgccat gctgtcgttg aaaaggttat
     4501 gggggctcag acctatattc caaatacgat tcagatggca gaagatacca gtattcaact
     4561 ggttacaggg ccaaacatga gtgggaagtc tacctatatg cgtcagttag ccatgacggc
     4621 ggttatggcc cagctgggtt cctatgttcc tgctgaaagc gcccatttac cgatttttga
     4681 tgcgattttt acccgtatcg gagcagcaga tgacttggtt tcgggtcagt caacctttat
     4741 ggtggagatg atggaggcca ataatgccat ttcgcatgcg accaagaact ctctcattct
     4801 ctttgatgaa ttgggacgtg gaactgcaac ttatgacggg atggctcttg ctcagtccat
     4861 catcgaatat atccatgagc acatcggagc taagaccctc tttgcgaccc actaccatga
     4921 gttgactagt ctggagtcta gtttacaaca cttggtcaat gtccacgtgg caactttgga
     4981 gcaggatggg caggtcacct tccttcacaa gattgaaccg ggaccagctg ataaatccta
     5041 cggtatccat gttgccaaga ttgctggctt gccagcagac cttttagcaa gggcggataa
     5101 gattttgact cagctagaga atcaaggaac agagagtcct cctcccatga gacaaactag
     5161 tgctgtcact gaacagattt cactctttga tagggcagaa gagcatccta tcctagcaga
     5221 attagctaaa ctggatgtgt ataatatgac acctatgcag gttatgaatg tcttagtaga
     5281 gttaaaacag aaactataaa accaagactc actagttaat ctagctgtat caaggagact
     5341 tctttgacaa ttctccactt ttttgctaga ataacatcac acaaacagaa tgaaaaggag
     5401 ctgacgcatt gtcgctccct tttgtctatt ttttaaggag aaagtatgct gattcagaaa
     5461 ataaaaacct acaagtggca ggccctggct tcgctcctga tgacaggctt gatggttgct
     5521 agttcacttc tgcaaccgcg ttatctgcag gaagtcttag gcgccctcct tactgggaaa
     5581 tatgaagcta tttatagtat cggggcttgg ttgattggtg tggccgtagt cggtctagtt
     5641 gctggtggac tcaatgttgt cctcgcagcc tatattgccc aaggagtttc atccgacctt
     5701 cgggaggatg ccttccgtaa aattcaaacc ttttcttatg ctgatattga acaatttaat
     5761 gcgggaaatc tagtcgttcg aatgacaaat gatatcaacc agattcagaa cgttgtcatg
     5821 atgaccttcc aaattctttt cagacttccc ctcttgttca tcggttcgtt tatcctagcg
     5881 gttcaaacct taccttctct gtggtgggtg attgttctca tggtagtctt gatttttggt
     5941 ttgactgctg tcatgatggg aatgatgggg cctcgttttg ctaaatttca aacccttctt
     6001 gagcgcatca atgccattgc caaggaaaat ttacgtggcg ttcgtgtggt caagtccttt
     6061 gtccaagaaa aagagcaatt tgctaagttt acagatgtct cagacgagct tcttggtcaa
     6121 aacctttaca ttggttatgc cttttcagta gtggaaccct ttatgatgtt ggttggttac
     6181 ggggcggtct tcctctctat ttggctggtc gcgggaatgg ttcagtcgga tccgtctgtt
     6241 gttggttcca tcgcttcttt tgttaattac ctaaaccaga ttatctttac cattgttatg
     6301 gttggatttt tgggaaattc tgtcagccgt gccatgattt ccatgcgtcg tattcgagaa
     6361 attcttgacg cagagccagc tatgaccttc aaggatatcc cagatgaaga gttggttgga
     6421 agccttagct ttgaaaatgt gacctttacc tatccaatgg acaaggaacc gatgctgaaa
     6481 gatgtgagct ttactattga acctggtcaa atggttggtg tagttggagc gactggtgca
     6541 ggaaagtcaa ctttggctca attgattcca cgtctctttg atccacagga cggggccatt
     6601 aaaatcggtg gcaaggatat tcgagaagtg agtgaaggaa ccctgcgtaa aacagtttcc
     6661 atcgttctcc aacgtgccat tctttttagt ggaacgattg cagataactt gagacagggg
     6721 aagggaaatg ctactctatt tgaaatggag cgcgcagcca atattgccca ggctagtgaa
     6781 ttcattcatc gtatggagaa aacctttgaa agtccagttg aagaacgggg aaccaatttc
     6841 tctggtggac aaaaacaaag gatgtcgatt gcgcgtggga ttgtcagcaa tccacgtatt
     6901 ctgatttttg atgattcgac ctcagccttg gatgccaaat cagagcgctt ggtgcaagaa
     6961 gctttgaata aggacttgaa gggtacgaca accattatta ttgctcaaaa aattagctcg
     7021 gttgtccatg cagacaagat cttggttcta aatcaaggac gattgattgg tcaaggcacg
     7081 catgcagact tggttgccaa caatgccgtt taccgtgaaa tctatgaaac acagaaatga
     7141 aagacaaact ataagaaaag tcaatagttt tatctaaact atttcttatt tcaatttgat
     7201 gatttggcga tgattttaga gcacggcaaa aagcccttga aaaagtccat tttttcaaag
     7261 gtaatcctgt gttgatttca gaaattacat cactttttgt tcgtcaaatg gcagctcttt
     7321 tttaggatat aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggctacattg
     7381 taatgttttc cttattctaa cttagtctta agataggtct tgaaagcaag tgaaaagcga
     7441 gggcatgctt tggcagcttg tatgagtacc taccgcagat gaggggaacc ccgtttgacc
     7501 attcttccag ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa
     7561 gcttgtaatt gagcaagatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc
     7621 gcccctaaac gattcccaat cccagtaacc gtcgtgatga tcgagttgaa ctcagccatc
     7681 aagtcattga cacatgtttc cgccttgtca atgagcctct tgtaatgttt gatgttttca
     7741 ttacacgaga taaaacgtct atgcgttatc aaactcatta ccaattaaaa caaaaagctg
     7801 tggttagatc ctttcggaaa ttgtcaagcg attggaggaa atgaactaat ccacagcggc
     7861 ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat ataatataag
     7921 gaggagtaaa atgaagacag ttcaattttt ttggcattat tttaaggtct acaagttctc
     7981 atttgtagtt gtcatcctga tgattgttct ggcgactttt gcccaagccc tctttccagt
     8041 cttttctgga caagcggtga cgcagctagc caatttagtt caagcttatc aaaatggcaa
     8101 tccagaactt gtatggcaaa gcctatcagg aatcatggtc aatcttggcc tgctggtttt
     8161 ggttctattt atctctagtg taatatacat gtgtctcatg acgcgcgtga ttgcagaatc
     8221 gaccaacgag atgcgcaaag gtctctttgg taagcttgct cagttgacgg tttctttctt
     8281 tgaccgtcga caagatggcg atatcctgtc tcattttacc agtgatttgg ataatatcct
     8341 ccaagccttt aacgaaagct tgattcaggt catgagcaat attgttttat acattggtct
     8401 gattcttgtc atgttttcga gaaatgtgac gctggctctc atcaccattg ccagcacccc
     8461 attggctttc cttatgctga ttttcatcgt gaaaatggca cgtaaataca ccaacctcca
     8521 gcagaaagag gtagggaagc tcaacgccta tatggatgag agcatctcag gccaaaaagc
     8581 cgtgattgtg caaggaattc aagaggatat gatggcagga tttcttgaac aaaatgagcg
     8641 cgtgcgcaag gcaaccttta aaggaagaat gttctcagga attcttttcc ctgtcatgaa
     8701 tgggatgagc ctgattaata cagccatcgt catctttgct ggttcggctg tacttttgaa
     8761 tgataagtct attgaaacaa gtacagccct aggtttgatt gttatgtttg cacaattttc
     8821 acagcagtac taccagccta ttatccaagt tgcagcgagt tggggaagcc ttcagttggc
     8881 ctttactgga gctgaacgaa ttcaggaaat gtttgatgca gaggaggaaa tccgacctga
     8941 aaaggctcca accttcacta agttgcaaga aagtgttgaa atcagtcata tcgatttttc
     9001 atacttgcct gataaaccta ttttgaaaga tgtcagcatt tctgccccta aaggccagat
     9061 gacagcagtt gttgggccga caggttcagg aaaaacgact attatgaacc tcatcaatcg
     9121 cttttatgat gttgatgctg gtggtattta ttttgatggt aaagacattc gtggctatga
     9181 cttagatagt cttagaagca aggtgggaat tgtattgcaa gattcggtct tgtttagcgg
     9241 aacgattcga gacaatatcc gatttggtgt gccagatgct agtcaggaaa tggttgaggt
     9301 agcagcaaaa gcaacccaca ttcacgacta tatcgaaagt ttgcctgata agtacgatac
     9361 tcttattgat gatgaccaga gcatcttttc agcagggcag aagcaattga tttcaatcgc
     9421 tcgaaccctg atgacagatc cagaagttct cattctcgat gaagcaactt caaacgtaga
     9481 tacggtgaca gaaagcaaga ttcaacatgc catggaggtg gttgtagcag gtagaactag
     9541 tttcgtcatt gcccaccgct tgaaaaccat tctcaatgca gatcagatta ttgtccttaa
     9601 agatggagaa gtcattgaac gtggtaacca ccatgaactt ttgaagctag gtggctttta
     9661 ttcagaactc tatcacaatc aatttgtttt cgaataagaa agaagttgtc ctatgtgggc
     9721 agctttttct tgtccataaa aaatgtttat cacagcctta aaaaaaacat attagacgaa
     9781 agtcattttg agtgatatga taggactatc gttagcattc gaaaggagag gcatcatggc
     9841 tagaacggtt gtaggagttg ctgcaaatct atgtcccgta gacgcagaag gcaaaatcat
     9901 tcattcatct gtatcttgta gattcgcaga gatcattcgt caagtcggtg gtctcccttt
     9961 agtcattcct gttggtgatg agtcagttgt acgtgattat gtggaaatga ttgacaaact
    10021 cattttgaca ggaggccaaa atgttcatcc tcagttttat ggagagaaaa agaccgtcga
    10081 gagcgatgat tacaatctgg tccgtgacga atttgaattg gcactcttga aggaagcgct
    10141 tcgtcagaat aaaccaatta tggcaatctg tcgcggtgtc caacttgtca atgttgcctt
    10201 tggtggaacc ctcaatcaag aaatcgaagg tcactggcaa ggactacctt tcgggacatc
    10261 tcactctatt gagacagtag aaggaagcgt ggtggctaag ctatttggga aagaaagtca
    10321 ggtcaactca gtccatcgtc aaagcattaa agatttggca cctaatttcc gtgtaactgc
    10381 tattgattca agagaccaaa ctattgaagc gattgagtct atcgacgagc accgcattat
    10441 cggtttacag tggcatccag agtttctggt taatgaagaa gatggcaatt tagaattatt
    10501 tgagtattta ttgaatgaac tgtaacgatt ggaacatctg gtcgttcttt cttttatttt
    10561 ttcaaaattt ttagaatgtg gcattttacg caaacgtttg aattctgata aaaattggag
    10621 aaattcgaca aaaaaacttg aaaaaaacga aggtaagcgt tatgatagaa aagaagaaat
    10681 attggaggaa gaacatgtca catattaaat ttgattattc aaaagtttta gacaaatttg
    10741 ttgcaccaca tgaagtggaa tacatgcaat cacaagtaac agcagcagat gaattgatcc
    10801 gtaaaggaac tggtgctggt agcgacttct tgggatggtt ggaccttcct gaaaaatacg
    10861 atcgcgaaga atttgaccgc atcttgaaag ctgctgagca aatcaagtca gacagcgatg
    10921 ttttggttgt gatcggtatt ggtggatctt accttggtgc aaaagcagca atcgacttct
    10981 tgaatcacca ttttgctaac ttgcaaacaa aagaagaacg caaagctcca caaatccttt
    11041 acgcaggaaa ctcaatctca tctacttacc ttgctgactt ggtagagtat gttgcagaca
    11101 aagacttctc agtaaacgta atttctaaat caggtacaac aactgaacca gcgattgctt
    11161 tccgtgtctt taaagaactc ttggttaaga aatacggtca agaagaagct aacaaacgta
    11221 tctatgcaac aactgaccgc caaaagggtg ctgttaaggt tgaagcagac gctaacggtt
    11281 ggggaacatt tgttgttcca gatgatatcg gtggacgctt ctcagtattg acagccgttg
    11341 gtttgcttcc aatcgcagca tcaggagctg acatcaaagc tcttatggaa ggtgcgaatg
    11401 cagctcgcaa agactacact tcagacaaaa tctctgaaaa cgaagcttac caatacgcag
    11461 ctgttcgtaa catcctttat cgtaaaggct atgcaactga gatcttggta aactatgagc
    11521 catcacttca atacttctca gaatggtgga aacaattggc tggtgaatca gaaggaaaag
    11581 accaaaaagg tatctaccca acttcagcca acttctcaac tgacttgcac tcacttggtc
    11641 aatttatcca agaaggaact cgtatcatgt ttgaaacagt tgtccgtgtt gacaaacctc
    11701 gtaaaaacgt gcttattcct actttggaag aagaccttga cggacttggt taccttcaag
    11761 gaaaagacgt tgactttgta aacaaaaaag caactgacgg tgttcttctt gcccacacag
    11821 atggtgatgt accaaacatg tatgtgactc ttccagagca agacgctttc actcttggtt
    11881 acactatcta cttcttcgaa ttggcaattg ccctttcagg ttacttgaat gctatcaacc
    11941 catttgacca accaggtgtt gaagcttata aacgtaacat gtttgccctt cttggaaaac
    12001 caggatttga agaattgagc aaagaactta acgcacgtct ataatagaag aaaagagtgg
    12061 tttgcccact ctttttactc tctttatcca tagaaattgg actcagccaa gacttgtgat
    12121 ataatataga aagcaaaaag gcagacgcct agataatagg agaaactatg tcaaaagata
    12181 tccgcgtacg ttacgcacca agtccaacag gactactaca catcggaaat gctcgtacag
    12241 cattgtttaa ttacttgtat gcgcgccatc atggtggaac atttctcatc cgtatcgaag
    12301 atactgaccg taaacgccat gtcgaggatg gtgaacgttc acaacttgaa aaccttcgct
    12361 ggttaggcat ggattgggat gaaagtccag aatcacatga gaattatcgc cagtctgagc
    12421 gtttggactt gtatcaaaaa tacattgacc aactattagc tgaaggaaaa gcctataaat
    12481 cttacgttac agaagaagag ttggcagctg aacgcgaacg ccaagaagta gctggcgaaa
    12541 caccacgcta catcaatgaa taccttggta tgagtgaaga agaaaaagca gcttacatcg
    12601 cagaacgtga agcagcaggg atcatcccaa ctgttcgttt ggctgtcaat gagtcaggta
    12661 tctacaagtg gcatgatatg gtcaaaggcg atatcgaatt tgaaggtggc aatatcggtg
    12721 gtgactggat tatccaaaag aaagacggtt acccaactta caactttgcc gttgccatcg
    12781 atgaccacga tatgcaaatc tctcatgtta tccgtggaga tgaccatatt gctaatacac
    12841 caaaacagct tatggtctat gaagctcttg gttgggaagc tccagagttc ggtcacatga
    12901 ccttgattat caactctgag actggtaaga agttatctaa acgtgatact aatacacttc
    12961 aatttatcga agattaccga aagaaaggtt accttccaga agcagtcttt aactttattg
    13021 ctcttcttgg ttggaaccca ggtggtgaag atgagatttt ctctcgtgaa gaactcatta
    13081 aactttttga tgaaaaccgc ctcagcaagt caccagcagc ctttgatcag aaaaaactag
    13141 actggatgag caatgattat atcaagaatg cagaccttga aaccatcttt gaaatggcaa
    13201 aaccattctt agaggaagca ggccgtttga ctgacaaggc tgaaaaatta gttgagctct
    13261 ataaaccaca aataaaatca gtagatgaga ttatcccatt gacagatctt ttcttctcag
    13321 atttcccaga attgacagaa gcagagcgcg aagtcatgac gggtgaaaca gttccaacag
    13381 ttcttgaagc attcaaagca aaacttgaag cgatgacaga tgataaattt gtgacagaaa
    13441 atatcttccc acaaattaaa gcagtccaaa aagaaacagg tattaaaggg aaaaatcttt
    13501 tcatgcctat tcgtatcgca gtttcaggcg aaatgcatgg gccagaatta ccagatacaa
    13561 ttttcttgct tggacgtgaa aaatcaattc agcatatcga aaacatgcta aaagaaatct
    13621 ctaaataaag aggatacaat aatggacatc tgggaaaaga tgtacgaaga agcacagaaa
    13681 ctatacaatc cacatgaagt atcagacttt gtttatgcca atcatgttgt agctgcagta
    13741 gaagcagaag atggacaaat atttacagga ttctgtatgg agggaacctg tggtgttttc
    13801 catctctgcg cagaacgggc ggccctcttc aatatgtacc aattttcagg acaaactaag
    13861 gttaagaaag tattagcctt tcgagacaaa ccaccttatg gtggaagttc agccatgcct
    13921 tgcggtgctt gtagagaatt ccttttagag cttaatgctg aaaataaaga tgcagaattc
    13981 atgatggact ataatataag aaaaacagtt aaagtcgcag aactaatccc ttattggtgg
    14041 ggaaaagaac gtgcttctaa gtttaatgag cgatagaaga gtcagtataa ttctggctct
    14101 ttttactata agttgcaaaa aaaataaaaa aaattagaaa aagtagttga caaagtttga
    14161 aaagactgta taatagtaag agttgaaaat aacaactcag gtccgttggt caaggggtta
    14221 agacaccgcc ttttcacggc ggtaacacgg gttcgaatcc cgtacggact atggtatgtt
    14281 gcgtcaggac cacttgataa aaaaagttta aaaaa
//
LOCUS       DBEJJE010000050        12795 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEJJE010000050 DBEJJE010000000
VERSION     DBEJJE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.50"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..238)
                     /locus_tag="ACL3F5_001689"
     CDS             complement(<1..238)
                     /locus_tag="ACL3F5_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CAT RNA binding domain-containing protein"
                     /protein_id="HGR0515452.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIIN"
     gene            complement(538..3216)
                     /locus_tag="ACL3F5_001690"
     CDS             complement(538..3216)
                     /locus_tag="ACL3F5_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0515453.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFNGDSEFFLCKRLKDKSQFVMERS
                     QFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKSFINDQGKIQYFPSYDYGWKQLL
                     PEKRSFQTLTDSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLLELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKVLREDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYGAMPLFGKVDEMTILRLESASIVSELVAGLR"
     gene            complement(3319..3462)
                     /locus_tag="ACL3F5_001691"
     CDS             complement(3319..3462)
                     /locus_tag="ACL3F5_001691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515454.1"
                     /translation="MTGQRLNELEINGIRLTKFKNGEIGIEFIWIDIENPPSDAIGWV
                     AKK"
     gene            complement(3502..4257)
                     /locus_tag="ACL3F5_001692"
     CDS             complement(3502..4257)
                     /locus_tag="ACL3F5_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR0515455.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(4328..6979)
                     /locus_tag="ACL3F5_001693"
     CDS             complement(4328..6979)
                     /locus_tag="ACL3F5_001693"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0515456.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNVDGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSCEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLVAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6972..7550)
                     /locus_tag="ACL3F5_001694"
     CDS             complement(6972..7550)
                     /locus_tag="ACL3F5_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0515457.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7550..8110)
                     /locus_tag="ACL3F5_001695"
     CDS             complement(7550..8110)
                     /locus_tag="ACL3F5_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0515458.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(8097..8675)
                     /locus_tag="ACL3F5_001696"
     CDS             complement(8097..8675)
                     /locus_tag="ACL3F5_001696"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGR0515459.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFSYNIMTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     IPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKCVDMKGSFIKKARKKDGKN"
     gene            complement(8958..9353)
                     /locus_tag="ACL3F5_001697"
     CDS             complement(8958..9353)
                     /locus_tag="ACL3F5_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0515460.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENDIKFK"
     gene            complement(9449..9703)
                     /locus_tag="ACL3F5_001698"
     CDS             complement(9449..9703)
                     /locus_tag="ACL3F5_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0515461.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9713..11047)
                     /locus_tag="ACL3F5_001699"
     CDS             complement(9713..11047)
                     /locus_tag="ACL3F5_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0515462.1"
                     /translation="MTDERIHILRDILLELHNGVSPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(11047..11280)
                     /locus_tag="ACL3F5_001700"
     CDS             complement(11047..11280)
                     /locus_tag="ACL3F5_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0515463.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(11683..11865)
                     /locus_tag="ACL3F5_001701"
     CDS             complement(11683..11865)
                     /locus_tag="ACL3F5_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515464.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11867..12646)
                     /locus_tag="ACL3F5_001702"
                     /pseudo
     CDS             complement(11867..12646)
                     /locus_tag="ACL3F5_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3751 a         2893 c         2267 g         3884 t
ORIGIN      
        1 gattaattat tttttcggtg atgtacacca actccaaagg aacgttaata aacatctctg
       61 taaaacgggt catattatct ctatttttga gaaaaaaact tttctcaata tcaattggat
      121 ttactttatc tccaattttt cttccaaaag ctattcccct tccaaaaaga agaatatcga
      181 tatctttttt actttgcgca attacggcat tgtggtttag tattcgtttt atgatcataa
      241 aatttccctt ttaaaataaa aggaacctac ttaaaaacat caagaaactt cttctgatgt
      301 gattaaatag gttcctgctc acttgtatta gtgataacat ccttttattt caatttttaa
      361 tggtgacatg aagcttaaat aattaataac tctgtaaccg tttttatttt atgatatttc
      421 aatctatttg tcaagtactt ataaaaattt ttttattttg tgtgattcga atgtgataat
      481 ggcaacagtc tcactaaaga aatgaaaatc atacatagaa atttttaaaa attttctcta
      541 tcgtaaacct gccactagtt cagaaactat actagctgat tccaaacgta atatggtcat
      601 ctcatctacc ttcccgaata atggcattgc accataccaa acaatagtct tattcaccaa
      661 aagaataggc gttactattt ttgattgagt aaaagacact ttaattttct ggctcttcaa
      721 ctggtctagc catgctttat ttgcaaccgt ctctggtata catatctcaa tttgactaat
      781 cctaaattct tttagaaaat tcatcagttt tgtctggtgc acataaggta aaataagcag
      841 acattcctgt ctttcccctg ctaagtcctc tctcaacacc ttctcatatc tactatcaac
      901 ataaacgaat tgtttctcct caccctcgat gacacgataa tccatctttc gataagctac
      961 ttgtcgtttc tgaaacatct tttctaaata aggaacatga atatccacat aatcgaaaat
     1021 acgcaccaaa gacttatcct tgtagtttct atgaatccga cctgcatact gaattaaatt
     1081 atttttccaa gaaaagggtg ctgccaagat aagcgtgtcc aactgaggta agtcaaaacc
     1141 ttcgccaatg tattttccag tagacaacaa aacaaaccct ttatctaact gttctaacgt
     1201 ctccagtaaa ctcgttcttt ctcggacttt ggtttttccg ctaataatgt aacagtcatc
     1261 aacctctttc tctttcaata acttttcaaa gacatctatc tgttgaattc gattaactaa
     1321 aaccaagata ttccgtcctt ctgccacttg ggctagaata tccttgagaa tcaactgatt
     1381 cctcgctgag tcagtagcaa tccaatcact aagctgtata aaattacttg ctttggtctt
     1441 ttcaatctcc aaatgaccaa aagaagtgaa tcttaattgc aattgccgtt taaaatccgt
     1501 ttccctctta tcagcagtat ggagtatctc accaattctc tgaaaaacaa taggctcatg
     1561 accattctta cgctcaggcg tagccgtcaa accgtaaaga tacttccctc taaactgagc
     1621 aacaactttt tcaaacatca aggcagagac atgatgacac tcatccacaa tcatcatctc
     1681 atactcatcc aaaagacttt gactattttc caacttaaat agagattgaa tcataacgac
     1741 atcaaccagt ttactcagcc atttcttagt cccaccgtac tgtccaacat agccgattac
     1801 cttttcacga cctgatgccg tataacggat agcctcctcc tcttcgaaag tcaaaaagca
     1861 gtttaagcga tctagccatt ggtctaagag ttgcttatta tggactagaa taattgtttt
     1921 tgttttccgt tcagagataa gagcagcacc taaaacggtc ttcccaaaac cagtctccgc
     1981 atgaagtaaa ccattttctt tagaagtcat atctgacagg gctaactctt gctcaaaagt
     2041 gagttctccc ttaaattcca cgctaataga cctttgtacc tttctcctat cttccacaga
     2101 tacctgctta aatttatctt gcaatggata cagcaaacct cttggcaacc ataaataatg
     2161 atcggattct ccaaataaat acattctctc aggaatttga taggttggct gtcgcatagc
     2221 ctgctttaaa taaaattcgg gattagaaaa tgaagccata tttttcaaga aaaacagtgt
     2281 cttgggtgtc acagacgatt tttcaagttg gatcatattg gataagacga tcttcaactc
     2341 cttgtccaat tcttgcttgc ctaactcttc ttggattaac agtgccactt tagcagttga
     2401 aaccctctga atttcttgta gatacctcca ttggtcttca taaggctgaa actgttcatc
     2461 cacaaagacc gttcgccctt gatggtaagc ttctccttga aaaggcaagg caatcaaatt
     2521 tccaaatccc cccttaggaa ggacatcctg atttggaaac atgcgatcaa aagaatcaaa
     2581 ggacagttgc atactttcct gcattgccaa ttctaatagt ttctttccaa acaagcgagc
     2641 ctctcgactc ggaatagctt cctcaaagaa gaaccaaata tggagtccgt gacccgaacg
     2701 agaaatctct agatgggctt ccatctggcg ttccctggct attcttcgaa tggttaaacc
     2761 agcttctttc caatctcctt catcaaaatc cagtaccaaa aaatgacagc tatcatctaa
     2821 gtgcatagga aagataccga tagctgtctc cccacgaaaa tgagatttca aaacggaatc
     2881 cgtcaatgtc tggaaactcc gtttttcagg tagcaactgc ttccaaccat aatcatagga
     2941 aggaaaatac tgaattttcc cttgatcatt gataaaactc ttagcataaa catcataacg
     3001 gccagcaaac acagaggtaa acaattgtaa tttttcttgc gtcgtcaagc gactactttg
     3061 aagttggaac atctcctcga actgagagcg ttccataaca aactgactct tgtctttaag
     3121 acgtttacac aagaaaaact cactatcccc attaaaagaa gaaaagacat caagtacttc
     3181 taccacaatt ccatccaaag acacaaaaac agccataaga gtcacctcct tgattcctat
     3241 aggctgatta taacaagaat agctgaaatt gtacacgaaa ataaaatcgc ttacttgtta
     3301 caatagcttt gaaaactttt atttctttgc tacccagccg atggcatcgc taggtggatt
     3361 ttcaatatca atccagataa attcaatacc gatttcccca tttttaaact tggttaaacg
     3421 aataccgttg atttccagtt cattgagtcg ttgacccgtc aagacttctc gttctttcaa
     3481 ctggaaaagt taagggggga actaatacaa atcttctaag cttctatatt caatgatttc
     3541 atttttgata atattctttt taaactcaaa atgttttaaa ggattatcga ttaacactaa
     3601 ctttggaata tcatctagat ttgtgaccaa ggataaaata aaatccgatt gaaactcctt
     3661 gactttttca aattcttttg cagttaaacg cacacgcccc ttagattttc ggataccttt
     3721 tacttcggca aggtaagaat actcttggac atctacctga aagtcatatc catcaccata
     3781 aagacgggca tcggttaact gtccaccttg gaatttttct tctttatcaa aatgaaggat
     3841 aaaataattc tcagcctcca ttcccgtttc ctgtagacgt ttgaatttag ttcgaactat
     3901 tggtttttca acgatggtta tgcctgtttt cttcccttca ctggcaagta acattttaac
     3961 tatttcagca taactatgaa catcttcatt tccaaacatc atatcaatta aatctttacg
     4021 aaaacgataa acttcagctt tctgccacca accttttcga ttattgtcaa aataaggatc
     4081 aaataaatcc attctatttt ttacaactcc agttgtttca gcaattccca gagaaaccac
     4141 atagcgataa aactccgact tgctagagca ttgaaattct tttataaaaa gcttgtcaaa
     4201 cttggcaaga ccgtagccaa ttaaatttaa caattcataa tgagggtgtt tggacatcac
     4261 tttctccatc aatagatatt gatttcatta taccaaaaaa acacggctca tcaccgtgtt
     4321 tctgtgttta tttcaccaac ttcttcatct catcaatacg tgctacggtc gcatcatact
     4381 tggcttggta gtcggcttgt ttgtcttttt ctttttggac aacttctggt ttagcgttgg
     4441 cgacgaagcg ttcgttgctg agttttttgc caaccatgtc gagttctttc tgccatttgg
     4501 caagttcttt ttccagacgt gccaattctt cttcaacatt caagaggtct accagtggca
     4561 agaagatttc ggctcctgta ataacgcttg acatagccag ttcaggtgca gggatggttg
     4621 atgcgatttc caagtgttct ggatttgtaa agcgtttgat atagttgaca ttgctgttaa
     4681 agaaggcttc caagtcgcta tcgcttgtct taacaaggat tgtgattggc ttacttgggg
     4741 ctacgtttac ttccgcacgc gcattccgaa cggcacggat caagtctttg agactttcca
     4801 caccagtgtg agccacaagg tcttcaaagg ctgggttgac agttgggtat tctgctgtca
     4861 cgatagagcc ttctgagatt tgtccaaaaa tttcctctgt cacgaatggc atgattgggt
     4921 gaaggagacg aaggatcttg tccagagtgt aaaggagaac agaacgtgtg atgactttct
     4981 cttcttcatt atcgctataa aggacttcct tggtcaactc aacataccag tccgcaaatt
     5041 catcccagat gaagttgtag aggatgtgac cagcaacacc aaactcaaac ttatcaaagt
     5101 tagcagttgc ttttccaatc gtttcattga ggttgtggag aatccagcgg tccgtcacat
     5161 taccagcctc acctgttgca acttttgtga cattgtcatg caccacatcc agcgtcaaac
     5221 ctccattgtt catgaggatg tagcgagaga tgttccagat cttgttaatg aagttccatg
     5281 aagcatccat tttctcacaa gagaaacgca cgtcttgtcc tggcgcagaa ccgtttgaaa
     5341 ggaaccatcg aagggcatcg gcaccgtatt tctcgataac atccattggg tcaatcccgt
     5401 taccgagaga cttagacatc ttgcgtcctt gctcgtcacg aataagaccg tggataagga
     5461 cgttttggaa tggttgacgg cctgtgaatt ccaatgactg gaagatcata cgagacaccc
     5521 agaagaagat gatgtcgtaa cctgttacca aggttgaagt tgggaaataa cgtttaaagt
     5581 cttctgagtc gacttcaggc cagcccatgg ttgaaaatgg ccagagggca gaactgaacc
     5641 aagtatccaa gacgtcttcg tcctgagtcc atccgtcacc ttctggagct tcttcgccga
     5701 catacatttc accatcaaca ttgtaccaag cagggatttg gtgaccccac cagagctgac
     5761 gagagataac ccagtcgtgg acattttcca tccattgaag gaaggtatcg ttgaaacgag
     5821 gtgggtagaa ttcgaccttg tcctctgtgt cttggttggc aatggcgttc ttagccaatt
     5881 ggtccatctt gacgaaccat tgagtagaca agcgaggttc aaccacaaca cctgtacgct
     5941 ctgagtgacc aacactgtgg acacgttttt cgattttgac gagggcaccg atttcttcca
     6001 acttagcaac gactgcctta cgagcttcaa aacggtccat gcctgaaaat tcaaaggcca
     6061 agtcattcat ggttccgtcg tcgttcatga cgttgacttg tggcaagtta tgacgttggc
     6121 caaccaagaa gtcatttgga tcgtgggcag gtgtgatttt cacgacacca gtaccaaact
     6181 caggatctgc gtgctcatct ccaacgattg ggatgagttt attagcgatt ggaaggatga
     6241 cgtttttacc aatcaagtcc ttgtagcgtg ggtcttctgg attaatcgca accgcaacgt
     6301 ccccaaacat agtctcagga cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca
     6361 gcatgtaatt catgtggtag aaggcacctt ctacatcctt gtgaatcacc tcaatatcag
     6421 aaagggctgt gcgagctgct gggtcccagt tgatgataaa ctcaccacgg tagatccagc
     6481 ctttcttgta aaggttcaca aagaccttac gaacagcttt tgacaaacct tcgtcaagag
     6541 tgaaacgctc acgagaatag tctacagaga gccccatctt gccccattgt tccttgatgg
     6601 tagtggcata ttcgtctttc cattcccaga ctttcgtcaa gaaagactca cgaccaaggt
     6661 catagcggga aatgccctca ccacgcaagc gctcctcaac cttagcctga gtggcaatcc
     6721 ctgcgtggtc catcccagga agccaaaggg tatcaaaacc ttgcatgcgt ttttgacgga
     6781 tgataatatc ttgcaaagtt gtatcccaag cgtgaccaag gtggagtttc ccagttacgt
     6841 ttggtggtgg aatcacgatt gaataaggct tagccttttg atcgcctgaa ggcttgaaaa
     6901 catcggcatc aagccatttt tggtaacgac cagcctcaac ctcggctgga ttgtatttag
     6961 gtgaaagttc tttagacatg tgtgtgtcct ttctctattt tgtttatttt attttgaatc
     7021 tgcttagcag cttcttctgc agacaaattc gtattattta ttttaaagta gtggtgcaac
     7081 tcattcggtt gatattggga atttaattga agtgtttcag cggtctctaa aatttctctt
     7141 tcagatacct caatatgtcg ttttaagggt ttgtgcttta atcgattctc cgttcgattt
     7201 cgacgtatgc actcttcaag acttgtttcc aactcaacaa aaagaatctc ttgatgataa
     7261 tcatccaaca aattctgaat ttgctttaaa tacatcagct gatactgatt tgaaaaatca
     7321 attacatctg ttaaaattac tgatcgctga tttcttgcac ttgctccaag gaatgaaaaa
     7381 gtgattccac gaacaaattc ccacatttcc tctgtatagt cctgatagat ttctagtgca
     7441 aaatcaatgg cttgatggtt ataaaatagg gtagcatccg tcagtcgaga taattcttga
     7501 ccaatggtca tttttcctga tgctggagca ccaatgatga aaagatgcat caaatcacct
     7561 cccactcact cttcagcaag gcatatctca aatcatcaca gcagttgcct tgagcatctt
     7621 tacggtctct tatgcgagct tcgagggtaa agccaagctt ttccgcgact cgttgacttt
     7681 gaaggttata tccaaagcaa gttagttcaa tcttgtgaag acccaaatct ttaaaggcta
     7741 agtcaatcaa ggcacgcgca gcttctggca cataacctcg cccccaatag tctgagtgta
     7801 aggtatagcc gatttccatc acatcatctt catggcgatg gttgaaatag atagagccaa
     7861 cgatcttatc cgttcctttg acgacaatcc cgtagcctgc tgggagattt tccttttgat
     7921 tacgctccgg aagaatgtgc tccagataat aaatctcatc ttccaaggtc ttgactggag
     7981 gaaaacctgc tggataggcg acctctggca aactagcata gtcaaagata tcctcagcat
     8041 ccgccacagt acggactcgt aaaacgagac gttctgtttc gattttatct ggcagctcag
     8101 ttcttgccat ccttcttcct cgcttttttg atgaaactgc ccttcatatc tacacactta
     8161 tccagatagc gataaacgcg ctgatatcca tctcccatga aataggttgg ggcaaacagt
     8221 tgatttttaa aatgtccctt ttcatccagg agttctgggg caacaagtcg ctcaagaatc
     8281 ttggcaaaga tgtggcaaat accgtcttcc tcaacaatcc tatctacccg acaatctaaa
     8341 acaagtggac aggcgtctaa aataggaatc tgagttcgtt cagaaatttc ataatgcact
     8401 cccaaacgtt ccaatttctc ctgatgactg ataaaaccag cctgctccat cgcaagcata
     8461 gaagtttcat cagaaatatt cacagtaaat ttttgatact gtttgatctg ctctgcggca
     8521 ttctctctcg caacgactcc aatcacaacc caatctccta gactataaga ggaactacag
     8581 gtcatgatgt tatagctaaa attctgatct tgatatccta aaataaaaac aggaaaacca
     8641 taatatagtt tattagtttt aaatgattgt tttataacaa cctcctttga ctaagacaca
     8701 aaagaaaagc cctgccatct acatgacagg gacgaatgtg tttatccgcg gtaccaccca
     8761 atttcgggcc aagcccgcat ctttagtctt taaaataaaa agacagaaat atttcatttt
     8821 ttcagtcatt agcaaccagt tttgacacat ttgtggactt ctcagcaccg ccactttctg
     8881 taaaatgtgg gattcaaaac acctctaatg gctctattgt agcaagattt tttcggaaat
     8941 gcaaggctca agaaaaatta cttgaacttg atatcatttt ctttcaattt cttgatggta
     9001 gctgggccga ttcctttcaa ggcaaggagt tctttttcag tccagttttt gaaatctgaa
     9061 gcagacttga ttccttcatc atagaaagtc ttggcacgat caagtggaag tccacccaaa
     9121 tttgctgcaa aatcttctac agaattagct actttttgag cttgctcttt ggtagcttct
     9181 actgcttgtt caactttttt agaaacagcc ttaccagctg cgcttgctga ctgttctgca
     9241 cgcttcacga ctttttttgt ctcatctaca accttagtca cagtacttga aaaggcacct
     9301 gcgcgacgga ggccatttcg taattgtttt ttacgattga gtttctttga catgataaaa
     9361 tcctttcaat aaaaaatccc tgctctgaca aggatttaac ataaacattc tatcaagatt
     9421 ttagtgaaaa atcaagaatc tttctcgttt aataatttcg ctcaccaaac aagccttctg
     9481 gcaaatcatg gaatcccttg cctgctttga agttttcaaa cttaccaagc aagaactgat
     9541 aagcatccaa gcgactctcg tagcgaatca tggcatcttt ggcacgctcg tcctggtctt
     9601 cttcgtaaac tttttgactt tccttgtgcg ccatatcgtt aatcatgatt tgggtattga
     9661 cccaagcttc aaattccttc ataaattctt gttcgtaact cattttttct ccttattcta
     9721 atccacgaaa atagtccgta tcaatctcac ggtagggctg gatatcctga acatactcca
     9781 acactccttg gaattctccg tcttcatcgt gtactgcagc ataggtgatg tggacaaact
     9841 tacctcgcga ctcagacttg aaccacattt catacttgtc tttgcttccc tcacgaagtc
     9901 ccttcatgat agccttgacc ttgtccagat acttaggcgg atgacagagt tcgacattgc
     9961 gcccgacttg ggacggcgtc cgtttgaaaa tcatctcatc agctggcgta ttgtcattgt
    10021 aatactggaa aatatcttct ttattgacaa aggtaatctc catagggaga tgattgagga
    10081 tgagattggc ctgctcgact gaaagatagc cattaccaaa agcctgttga ctatggcggt
    10141 ccagcacagc ttccttttcc ttaggggtaa aggtaatggt aaaatggcct tctggcgtat
    10201 ctatgacttg ttgaacttga ccttctgccg tatctagctg tacaggctcc tctgcaatct
    10261 tttcctcaat aaagctctgt cgttctggca cccatttctc tgacggacgg atgatggcat
    10321 agccataggc atcgctctcc tccgcaatct gaagccagtc atcctgagta aaagactcaa
    10381 ggagaatcat gaggaggatg gactcttcct tgaaaatcat actttcaaac tctgtcgcaa
    10441 aagcttcaaa agcttccttt acactgctaa ttgacacttc tggtagtgac ttggctgtcg
    10501 ttagagctgt ttgaaagagt tccctaatct gatcatccac tccccacata actttgggag
    10561 gtgaatcgtg tccatagcgc tccatgatag gaaagaagag ttcttcttta cgttggtaat
    10621 ggatgtcaaa ttgccccaca agtcccatct gacgcaccaa gcccttgcgc atctccgcaa
    10681 gcatttcctc gtcttccatc aactcatagg tatctaacaa tctacgaatg cgaatcaaag
    10741 ctgcacggag ggccaaattt tcttccttaa agacacgaac tgggtgccca gggtgttcgg
    10801 tatctaaaac ttcgacacct ttgatagcat ttttaaaaag attagcatgg acatcacaga
    10861 gttccataac atcttcaaaa gtgacgcccg aatccgagtt catcagctcg tgctccataa
    10921 gggaaatctc gatggctgac acgcccgtaa aggtcgcatc aaagcgatct tgaaccgact
    10981 caggagagac gccattgtgc aattctaaca aaatatcccg taggatatga atccgttcat
    11041 ctgtcattag tctaatccaa tcacttcgta gccattcgct tccagtgtgc gtacaatctt
    11101 gtccatagga gttcctgcta gcttagaacc ctgtttaagt gatactttac gaccaactgt
    11161 attgcgcatt aagggattgg caaggggttt aaaacccaac tccactagaa tttccaagac
    11221 ttctggatgc ttgtccacca cttctgcaac aggaattgac acatcgatga tattgtccat
    11281 gacgacctcc attgtatgtt ctaatactca atgaaaatca aagagcaaac taggaagcta
    11341 gccgcaggtt gctcaaaaca gtgttttgag gttgtggata gaactgacga agtcagtaac
    11401 atatatactg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag tataaaatga
    11461 ttttactgct tatattatac catatggaga gagattaaaa aactagcagt ggggttcctg
    11521 ctagttttct gcgacttgga ttaccatcta gataagttta aagaaccaat ccaatatctt
    11581 gtaaaacagc aattgaactg caaaagaaat gatcatccaa aagaatttca caatcccaat
    11641 aatcggtttg ataaaaagaa tagcaagaag accaaaaaaa tttcattctc tctcctctgg
    11701 cttaatgagc caccgagccg tatccattag cttatctgca ataaagagtt ttcccagacc
    11761 aacaacgaca tggtcagctt tctttatcgt tttcatcact tttacacctt gcacggtcaa
    11821 aaagtaatta ccataaattt tagcaaaagc tttgatagga ttcatattac tctcctttga
    11881 tgatttcagc ctcttttcgg attgtttcaa catcttcttg atattgaact tcactatagt
    11941 taactagctt ggacaattct ttctgcaagc tttcacccat cggtttcata gttgcaaagg
    12001 ttaaaccacc tgaaatgata ccacccaaga taggaataaa tttccccatt cctttggcca
    12061 gccctccctt ggtaagattc acaccaaata ttcttaagac ttttttcaaa ataggatacc
    12121 aaagcgtctt tgttaaagct ttattaggta ctgttttcat tacctgtttg gcaattgtta
    12181 taccaccagc acgtagcaaa gcagcagttc cattcacccc ccaacatgac gcctagataa
    12241 agcaaaaggg tattttgagc atcttcactc aactcatctc gtgaagccca aagatcctca
    12301 taaccataaa tataacctaa ttcttgggcc aatttcagag agaaaccata aaattgagcc
    12361 acatcagctg gaatggtaat tgccatagca agccctccag gtaatcctgc caaaacagaa
    12421 gtcccactcg ctaataaaac attatcccta atacaggcat tagccactcg atctaagatt
    12481 tcttgagata agagagacgt tggaccttgt tccaataagg tagaatgtcc tgtggaccca
    12541 attctttgga aaacttatcc actaaaaatt tcgaacgatc aaccttaaca actggtagtt
    12601 ttaccacttg ttgtaatact tgcatagcta agtcttgttc agccatatac aaactcctta
    12661 tttctttttt acaccttatc atattatatt tcctacaaaa aaagcatttt ctaattagat
    12721 aacattaaaa aatacagaac ccctttttta tagtaaaatg aaacaagaac aggacaaatc
    12781 gatcaggaca gtcaa
//
LOCUS       DBEJJE010000051        12308 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEJJE010000051 DBEJJE010000000
VERSION     DBEJJE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.51"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..359
                     /locus_tag="ACL3F5_001703"
     CDS             <1..359
                     /locus_tag="ACL3F5_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515465.1"
                     /translation="KLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHP
                     IFQTVLKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFI
                     ALNIKKERTKFVLSQA"
     gene            complement(445..1647)
                     /gene="rpsA"
                     /locus_tag="ACL3F5_001704"
     CDS             complement(445..1647)
                     /gene="rpsA"
                     /locus_tag="ACL3F5_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0515466.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1809..1880)
                     /locus_tag="ACL3F5_001705"
     tRNA            complement(1809..1880)
                     /locus_tag="ACL3F5_001705"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1846..1848),aa:Gln,seq:ttg)
     gene            complement(1890..1970)
                     /locus_tag="ACL3F5_001706"
     tRNA            complement(1890..1970)
                     /locus_tag="ACL3F5_001706"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1934..1936),aa:Tyr,seq:gta)
     gene            complement(2020..2250)
                     /locus_tag="ACL3F5_001707"
     CDS             complement(2020..2250)
                     /locus_tag="ACL3F5_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0515467.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2418..3062)
                     /gene="pcp"
                     /locus_tag="ACL3F5_001708"
     CDS             complement(2418..3062)
                     /gene="pcp"
                     /locus_tag="ACL3F5_001708"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0515468.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3077..4000)
                     /locus_tag="ACL3F5_001709"
     CDS             complement(3077..4000)
                     /locus_tag="ACL3F5_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0515469.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSVFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3997..4686)
                     /locus_tag="ACL3F5_001710"
     CDS             complement(3997..4686)
                     /locus_tag="ACL3F5_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0515470.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4751..5455)
                     /locus_tag="ACL3F5_001711"
     CDS             complement(4751..5455)
                     /locus_tag="ACL3F5_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515471.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5511..6533)
                     /locus_tag="ACL3F5_001712"
     CDS             complement(5511..6533)
                     /locus_tag="ACL3F5_001712"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0515472.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6665..9136)
                     /gene="parC"
                     /locus_tag="ACL3F5_001713"
     CDS             complement(6665..9136)
                     /gene="parC"
                     /locus_tag="ACL3F5_001713"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0515473.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9337..9541)
                     /locus_tag="ACL3F5_001714"
                     /pseudo
     CDS             complement(9337..9541)
                     /locus_tag="ACL3F5_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9556..11499)
                     /gene="parE"
                     /locus_tag="ACL3F5_001715"
     CDS             complement(9556..11499)
                     /gene="parE"
                     /locus_tag="ACL3F5_001715"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0515474.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11635..12276
                     /gene="plsY"
                     /locus_tag="ACL3F5_001716"
     CDS             11635..12276
                     /gene="plsY"
                     /locus_tag="ACL3F5_001716"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0515475.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3562 a         2800 c         2152 g         3794 t
ORIGIN      
        1 acaagctttt gagctattca caagacttga aacaccacta tcagctctat cagctcttgc
       61 tttttcactt ccagaataag gaaccagaga aatttttcgg acttattgag gacaatctta
      121 agcaggttca tcctattttt cagactgtcc ttaaaacctt cctcaaagat aaagaaaaga
      181 ttatcaacgc ccttcaacta cactattcta atgccaaact ggaagcgacc aataatctca
      241 tcaaacttat caagcgcaat gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga
      301 tttttatcgc tttgaacatc aaaaaagaaa ggacgaaatt tgtcctttct caagcttagc
      361 ttttcttcaa cccactacag ttgacaaaga gccagaaaaa tcccttgttt agtaaacaaa
      421 ggattttgtg aattttcaat ttgattaaag ttcgatatca ccaaacaaat cagccattga
      481 aaatcctgtt tgtgtttctg gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg
      541 tggacgagca gcacgttttt cttctttttg tccttcttct tgggctggac gttcttcaag
      601 agctttaata gaaagtgaca cgcgttctgc atctgcgtta acttcaagaa ctttaacttg
      661 aacttcttga ccaactttaa gagcttcttt tggattttca atccgtttgt gtgaaatttg
      721 tgatacgtga acaagtccat cgatacctgg caatacttca acaaatgcac cgaagtcagt
      781 caaacgttta actgttcctt ctactacatc acctttagcc aatttttgct caacgccatc
      841 ccatggtcct ggtactgttg ctttaagtga aagtgataca cgtccttctt cttcgttaag
      901 atcaaggatt ttcacttcaa tttcttcacc aacagttaca actgattttg gtgatacgtt
      961 acgttcatgt gacaattcag tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa
     1021 agcgccgaag cttgtgatac gagcaacttt accagttaca acatcaccaa cagccaattt
     1081 accgaatact tcagcgcgag ctgctgcagt agctgcttca acaacttcac gacgtgaaag
     1141 gatgaagcgg ttttctttag cgttaacttc tttgatttta gtatcaaatt cttgacctac
     1201 aaaacgctca gcgttacgta cgaaacgagt atccaacatt gaagctggga taaatccacg
     1261 aacaccttca aattctactg aaagtccacc tttaacggca cgcgttcctt taacagtaac
     1321 aacttcttct tcgcgaccaa caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt
     1381 agatacaagg tatgtaactg tatcagtatc tttaccaact acttgacgaa gtacaagaac
     1441 atccaatact tctcctactt taacaaagtc attgatatct gcatcacgat cgtttgtcaa
     1501 ttcgcgaaga gtcaagacac cttcaacacc agttccagag attgcaacgt tagcttgagt
     1561 cgcatcaact gtcaatactt cagcactaac aacatcacca gtctcaactt gactaacgct
     1621 atttagcaaa tcttcaaatt cgttcatcta aaaaatcctc caacaatcaa gtttttctta
     1681 aacttgacat acttataatt tttttcctaa gcacccgcaa ggacatgttc atatcattca
     1741 cgtctttcaa ttataaaaat aaaataccct aagatatttt gctttctatc ttgattatta
     1801 cctaagaact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag tcccttgcct
     1861 taccgcttgg ctatacccca ttaatgaaat ggagagagag ggattcgaac ccccgaaccc
     1921 gaaggagcgg atttacagtc cgccgcgttt agcctcttcg ctatctctcc tacaatcaac
     1981 atggactatt atatcatgaa aatttcaaaa aaacaagact tattttgcta aattataatt
     2041 ttcaatcaaa atttccacag ctttttccaa ttttttataa aaactatcga cattcccatt
     2101 ctttataatg gcaaattgtc cgtctaattc ggcaatttct ccgataactt ttttaccgat
     2161 agtcaatgta taaccttcaa aactgtcttt accaacatta actttggcat ccgctacttg
     2221 aatttcgatt tttttatctt tcttgctcat ttcatacctc tcttcacttt ttctatttta
     2281 caagaaaatc ctaaaactag caagaaaaaa ctctatatca ggcttctctg atatagagtt
     2341 ttatgtaaac aacctcaatt gatttagcat agttaatagt tagtaaacaa gcataattga
     2401 ctatcctttt taggttatca gtgagtctca ccgcctacta actgcaaatc cttatctttg
     2461 tagtctacaa tagcttcaat agctacctct atgcctctta caatatcaca tagactcatt
     2521 cctgcagtat tcggcttatt tactacttgt tccatcatat atggaatatg catgaaacct
     2581 gctctcatat tagggaattt tttatccact aaataaagag cttggtacat caaatgattg
     2641 caaacaaagg ttcctgcact attggataca actgccggaa gtccctgttt tttgatagct
     2701 tgtaccatcg ctttgatagg taaactacta aaataggccg atgctccatc aatacgaatc
     2761 ggtgtatcaa ttggttgatt gccttcgtta tcaggtatgc gagcatcatc ttgattaata
     2821 gccactcgtt caggtgttaa gccggtcctg ccgcctgctt gtccaataca aagtacagca
     2881 tctggttgat atcgtaatat ttctgcctct aaaacttctg acgacttata aaaaaccgtt
     2941 ggaatttcta cccagcgaac ttcagcccca ttaatctcag atggtaataa ttttacagcc
     3001 tccaaagctg gattaatctt ttcacctcca aaaggattaa aacctgtaac caatattttc
     3061 attttatttt cctttactaa aatgcgagaa agtacattaa gaatatgtga ataacaatca
     3121 ttactagagc aacacctgct tgagccttta taacgccatt ctgatctttc atatccatca
     3181 atgctgctgg tagagcgtta aaattagcag ccattggggt caataaggtc ccacaataac
     3241 ctgctgtcat ggcaagagca ccagccacaa ttggattagc tcccagagca aatacaaagg
     3301 gaactccaac acctgctgta ataacggtga atgctgcaaa agcatttccc ataatcattg
     3361 tgaatagaac cattccaaga acataagcca aaactcctat aaagcgacta tctgaaggaa
     3421 caataccgct aatcagatga gagataacat caccaacacc tgctacagta aaaatagccc
     3481 ccaaagcccc taataattga ggaacaatcc cacttgttga aacttgctga gtcattcgat
     3541 tattttctga taacagactc ttagggtgac tattggtaat cacaagaaca gaaattgtag
     3601 caaacaaggc ggcaaggcta atcgaaatct tgctaaattc tggaatcatt tgcgctaaga
     3661 ccaacgcaag tattgccatc agcataactg gaataaaaat tttatttttc aacctgttag
     3721 attcaatatt ggctttcatt tcatctaagg atggcaaggt tccgatacgg acttgcttaa
     3781 acaatgttaa cagcgataat aggattacaa taataccaat actcatattt ggcatatagg
     3841 aaccacctat aaacgtaata gacaatagag tccaaaatac agatgtccca agtcgaactg
     3901 ggtttgtttt atctttataa ctacaatagg ctgtatggag aaattgacaa ccaatcacaa
     3961 tataggtcaa ctctaatagt tgctttgcca actctgtcat ttttgttctc ctcccctagt
     4021 cttttttgat atcaattttt tatcaaataa ataattgtaa atccccacta caataagtgt
     4081 tataacagca acaataatag atgtagaagc aatccctgca taattgcttt catagcctaa
     4141 ctgatctaat gttcccccta tcaagaggac tcccccagca cctacaaacg tattttgagc
     4201 aaagaaattc ccaaaatttt cattcgcagc cgcacgcgct tttattgtct catcttcaac
     4261 ctctgttaac tttctaccta attgagactc tgcagctgct tctcccatag gttgaaccaa
     4321 aggtctgaca aactgagggt gtcctcctag acgaattgaa aagaaaccag ctaactctcg
     4381 aataaagaaa taaactgtat agaagtttcc aactgtcaga cctttaatct ttcgaatcaa
     4441 atcgattgat cgttgcttga gtccaaaggt ttctgacagc cccacaagag gcaaggtaac
     4501 cataaaaatc gtgagcactc gctgattgct aaattctttt cccaaaatct ccaaaaattc
     4561 aacgagagaa acacctgaaa ctaaagctgt aaccaaacca gctaagacta ctgttgcaat
     4621 tgtatcaaat tttaaaataa aacccacaac aatgattgct attcctatta atctaatcca
     4681 ctccatatca aactccttta tattcaaaat gacagtattt taaaaatttt atcaagatca
     4741 ataccattcc ttatttaatg tatttttcta gttctttttg gtatttgcta ttggattcca
     4801 atttttcttt ttgccatttt ttaaaaacct cgttatattc ttttgttgta acaatatctt
     4861 tttgcaattt cattccttta aagatatatg gttccccctt aataccaact tgtgagtatg
     4921 gttttgagaa tggtactacg ttacttacaa ctggagaacc accagatgaa gctgttggca
     4981 tcaataatga actatctgtc gaccaagctt gagctttggc atatttttca tatctcttct
     5041 ctaggtcagt ggtctcagaa acagcatctt ctaacaattt cttatattta tccaaaccag
     5101 gtttagctac aacatcctta tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac
     5161 cagattttgg atccataata ttcaagtaag acgctggatc ttgatagctt ggagcccatc
     5221 ctgtactatt caaatcatag tctttttgag aaggagcaac attgccgtat ttatcatttt
     5281 ccatcaaacc atcaataaca tttccaataa cgtctgtcgt cgatgttcga gtcgctatac
     5341 tgtagcccaa tgatgctgga tctactgcat agacataaga aaatgttgtc ggtgcatctg
     5401 cttctttatc agtttttcca caagccacta aaatagctga cgtgctcagg accactcctg
     5461 ctgttaagag ccactttttc tatttcataa aaaatctcct ttggtttatt ttaatctact
     5521 tttacaatcc aaccttctgg cgcttcaata tcgccaaact gaatacccgt caattcatta
     5581 tataatttac gcgtcacagg acctacttct gtttcactat agaatacatg gaaatcatca
     5641 ccatgttgaa tacctccaat tggagaaata accgctgctg taccacaggc acctgcctct
     5701 acaaaacggt caagattatc aattggaaca tcaccctcaa taggagttaa tcccaagcga
     5761 tgttctgcca aataaagcaa ggaatacttg gtaatagatg gcaagataga tggactcaat
     5821 ggtgttacaa attcattatc agctgtaatt ccaaaaaagt tagctgatcc gacttcttca
     5881 atctttgtat gagttgatgg gtccagatag ataacatctg agaaatgacg tgacttggcc
     5941 atttttcctg gtaagagact tgcagcatag tttccaccaa ccttagccgc acctgtacca
     6001 tttggtgctg cacggtcgta ctcatcctga atcaagaagt tggttgggac caaaccacct
     6061 ttaaagtaat ttccaactgg catagcaaag atggtgaaaa tgtattcttc tgccggtttt
     6121 accccgataa tatctccgac accaatcaaa agagggcgaa gatataaggt tccacctatt
     6181 ccgtatggtg gtacgtattc ttcattcgca cggacaactg ctttacaagc ttctacaaac
     6241 atgtctgtcg gaacttgtgg catcaagaga cggtcacatg tacgttgcag gcgtttagca
     6301 ttttcatcag gacggaacag ttgaacactg ccatccttag tacgataagc tttcaaacct
     6361 tcaaatgctt gttgtccata gtgaagactt ggagaagact ctgaaatatg caaagttgca
     6421 tcctctgtaa gctctccttg atcccattgt ccatttttga aatgagcaag atagcgataa
     6481 ggtaatttca tataggaaaa accgaggttt tcccaatcaa tcgttactgt catattccac
     6541 tccttattct aaaaacctat ttcttatatt ctacactatt tttctaaaat agcaagtata
     6601 ttttgtaatt ttcagaaaat ttctccaata aaaaccagct cttagaactg attcttcatt
     6661 tcacttattt atcttcagta actacttcct gaagataagc gtcaaaaact tcttcatctg
     6721 aaatcgtgtc agaaatgaag cttccattgc tagtgcgttc tgacaagttc aagtcttgca
     6781 atcggctttc atagattgtt cctttattgg attggacaag cagagtttgg tcgttcacat
     6841 ccacttccgt actgaagaaa tcgccaacaa atccttgctc tgcaactgct cctgccaaga
     6901 agacacgatg cggtttgttt ttcaactcac gcaagacttg taatcctcgt ttggcacggc
     6961 tggttgctag aatttcctca atggaaacac gtttcaagct tccacgctgg gtcaagaggt
     7021 agaaggacga agtattacag ataaagccag attggaggac atcatcttct ttcaaattca
     7081 tagccttgac acctgctgcc ttagcaccga caaccggaac ctcttcgata ttgaaacgca
     7141 gggcataacc attttgacta accaagacaa catcatctag tttaatcgga gccactgcta
     7201 caatctgatc tgtatcgtct ttgagcttag catacttgac agacttagat ctataggtcc
     7261 gccatggagt gaattctttt cgctctaccc gtttgatttg accaaggcga gtcgctgcaa
     7321 agtaggttgt cgcatcgtca aactgatcca gtacttccac ataaaggatt gcttcattcg
     7381 tttcaaagtt tgtgatggtt tggctcagat gctctccgat gtccttccaa cgaatatctg
     7441 ccaactcatg gattggtctg tagatgacat ttccaagact tgtgaacatc aagaggtgct
     7501 gggttgtctt ggcagattga acaaaaatca aacggtcatc atcacgcttg ccaatttctt
     7561 ccaaggtgga agccgcaaag gaacgtggac tggtacgctt gatgtaacct gccttggtca
     7621 cgctgacgta ggtatcttcc tcagcgataa gactagctgt atcaatctca attgctttcg
     7681 cagtgtcttc taaagaactc aaacgaggag ttgcaaattt cttcttgacc tcacgaagtt
     7741 ctttcttcat gagattgtac atagtccttt catcaccgat aatagccacc agcatagcaa
     7801 tcttctcacg aagctctgct tcttcttcct gcaagacaac cacatcggta ttggtcaaac
     7861 ggtacagttg caaagttacg atagcctcag cctgttcttc cgtaaaatca tagctaactt
     7921 tgaggttttc cttggcgtcc gccttattct cagaagcacg gataagagca atgacttcat
     7981 ccaaaatcga aatcacacga atcaaacctt cgacgatatg gagacgtttc tcagcctttt
     8041 ctttgtcaaa gcgtgaacgc gccaaaatca cttctcgacg gtgagcgatg tagctagaca
     8101 ggattggaac aatcccaacc tgacgaggtg tgaaattgtc aatcgccacc atattaaagt
     8161 tgtagttgat ttgtaggtcg gtgtacttaa ataagtagtt gagaacaagc tcagtattag
     8221 cgtctttctt aagttcgata gcgatacgaa gaccatcacg gtcagactca tcacgaacct
     8281 cagcaatccc agctaccttg ttattaacac gaacatcatc gattttcttg actagattgg
     8341 ccttattgat ttcataagga atctcagtaa taacgatttg ttccttacca ccttttagct
     8401 tttcaatttc agtcttggaa cgaacaacca cgcgcccttt cccagtctca taagctttct
     8461 tgatttcatc acgaccctga ataatagccc ctgtagggaa gtctggtcca ggcaagaatt
     8521 ccatgagttt atcaatcttt gcagttgggt ggtcaatcat gtaaactgca gcatctatga
     8581 cctcagctaa attatgggga ggaatgtctg tggcataacc agccgaaatc ccagtcgaac
     8641 cattgaccaa gaggtttgga aaggctgctg gcaagaccgt tggttctttc tccgtatcgt
     8701 caaagttcca tgcaaaagga actgtctttt tctcgatatc ctgaagaagg tagcctgcaa
     8761 tttcagacaa acgtgcctca gtataacgca tagccgcagg aggatctccg tccatagaac
     8821 cgttattacc gtgcatttca actagaatct cacgattttt ccagttctgt gacatacgaa
     8881 ccatggcatc atagatagaa gaatccccgt gtgggtggaa attccccatg atgttcccga
     8941 ctgacttggc cgacttacgg tagctcttgt caaaagtatt gctatcctta ttcatagaat
     9001 aaagaatacg gcgctgaacc ggcttcaacc catcacgaat atctggcaaa gcccggtctt
     9061 gaataatgta cttggagtag cgaccaaagc gctctcccat gatgtcctcc agggacatgt
     9121 tttgaatgtt agacataaga tacaaagccc ataaaatacc aagtgaaaat agaaaattct
     9181 tgaagtaagc aaactcacaa gagaatttat ctttttcaca cagtatctag ggcgtgttca
     9241 actcctttca aagaatgtag agtaggtttt tatgcagtaa aagatatttt acgggaattc
     9301 gtcccgtgtt cagttacgat aagtaaccaa actatcctgt ttgtattttt caatatgaaa
     9361 atatggtttt ccaaaattag tcttagtttg tgtcttagcc gctcccttaa acgcctcttt
     9421 gagataagca ctcatagcag attcttcatt aataatcctg caattttttc aaaccaagat
     9481 tttcaaactg ctttttcaca tagtcattca catccgactc taatttccag tttactaaca
     9541 tattattttc tttcattaaa acactgtcgc ttcttctagc gtaaacttga cattatcttc
     9601 aatccattta cggcgtggtt ctaccttatc tcccatgaga acattgacgc ggcgttcggc
     9661 gcgcgctaaa tcttcaattg tgacacggat gagggtacgt gtttctgggt tcatggttgt
     9721 ttcccagagc tggtccgcat tcatctcacc aagtcctttg tatcgttgga gggtagcgcc
     9781 tttaccgaac tgtttacgga gttcttctag ttctccgtcc gtccaagcgt aggccacttc
     9841 ttctttcttg cctttacctt tggacatctt gtaaagaggt gggagggcaa tatagacatg
     9901 acctgcctcg actagcggac gcatgtaacg gtagaaaaat gtcaagagca aggtctggat
     9961 atgggcaccg tcggtatccg catcggtcat gataatgatc ttatcatagt tggcatcttc
    10021 aatagagaag tctgctccaa cacccgcacc aatggtataa atcatggtat tgatctcttc
    10081 atttttgagg atatccgcca tcttggcctt ggctgtattg acaaccttac cacgaagagg
    10141 tagaatagcc tggaacttgc ggtcacgacc ttgtttggca gaaccaccgg cagagtcccc
    10201 ctcaactaga tagagttcat tcttagcagg attcttagat tgggctgggg tcaatttccc
    10261 agacaacaag cccttatctt tcttgttttt cttcccattt cggctctcat cacgcgcctt
    10321 acgtgctgct tcacgagcat cacgggcctt gatagccttg cggatgaggt tagaagctaa
    10381 ttccccattt tccataagga aaaaggtcaa cttatcagcc actattccat ccacaactgg
    10441 gcgagctagg gggcttccta gtttatcctt ggtctgtcct tcaaactgca agtgttcttc
    10501 aggaactaag atagaaagaa cggccgctag tccctcacga tagtctgaac cttcaaggtt
    10561 tttatctttt tccttgagaa gacctgtttt acgtgcatag tcattcatga ccttggtaat
    10621 ggcagacttg agtcctgtct cgtgcgttcc accgtccttg gtgcgaacgt tattgacaaa
    10681 ggatagaatg ttatctgaga atccgtcatt gtactggagg gctacttcca cttgaaaacc
    10741 attgtcttcc ccttcaaagt aaagaactgg cgtcaagatt tccttatctt cgttgagata
    10801 agaaacaaaa tcttgtactc cattctcata gtggaactca atcgcttcat ctgttcgctt
    10861 gtccgttaaa gacaaggtca catttttcaa gagaaaggct gattcattaa ggcgctctga
    10921 aatggtattg tacttgaaat ctgtcgtaga aaagatagtc gcgtcaggca taaaagtaac
    10981 tttggtgcct gttttagact tgggtgctgt accgattttc ttcaaagtcg tgacaggttt
    11041 tccaccattt tcaaaacgtt gcttgtaaac tgcgccatca cgggtaattt caacttctaa
    11101 ccagctagaa agggcgttaa caacggaaga acccactccg tgaagtccac ctgatgtctt
    11161 atagccacct tgaccgaatt tccctccggc atgaagaatg gtaaagataa cctcaacagt
    11221 tggaattccc atagcgtgca tacctgtcgg catcccacgt ccatggtctt gaaccgttag
    11281 actaccgtct ttattgatag ttacatcaat acgatcacca aacccagaca aggcttcatc
    11341 gactgcatta tcaacgattt cccaaactag gtgatgaaga ccagcgccat cggtcgatcc
    11401 aatatacatc cctggacgtt ttcggaccgc atccaaccct tctagcacct gaatagcatc
    11461 atcattataa ttgttaatat tgatttcctt ttttgacaca aggaacctcc tattcgttca
    11521 tctttactat tctacaggtt ttccaaggat tttgcaaaat ttttctttct ccgatgtgac
    11581 aatttcagca gagattctct gcttttcttt cccaattcat gatataatag gagtatgatt
    11641 acaatagttt tattaatcct agcctatctg ctgggttcga ttccatctgg tctctggatt
    11701 ggacaagtat tctttcaaat caatctacgc gagcatggtt ctggtaacac tggaacgacc
    11761 aacaccttcc gcattttagg taagaaagct ggtatggcaa cctttgtgat tgactttttc
    11821 aaaggaaccc tagcaacgct gcttccgatt atttttcatc tacaaggcgt ttctcctctc
    11881 atctttggac ttttggctgt tatcggccat accttcccta tctttgcagg atttaaaggt
    11941 ggtaaggctg tcgcaaccag tgctggagtg attttcggat ttgcgcctat cttctgtctc
    12001 taccttgcga ttatcttctt tggagctctc tatcttggca gtatgatttc actgtctagt
    12061 gtcacagcat cgatcgcggc tgttatcggg gttctgctct ttccactttt tggttttatc
    12121 ctgagtaact atgactctct cttcatcgct attatcttag cacttgctag tttgattatc
    12181 attcgtcata aggacaatat agctcgtatc aaaaataaaa ctgaaaattt ggtcccttgg
    12241 ggattgaacc taacccatca agatcctaaa aaataaaacg ccagttctgt actgacccca
    12301 aaaagtta
//
LOCUS       DBEJJE010000052        12199 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEJJE010000052 DBEJJE010000000
VERSION     DBEJJE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.52"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(200..2458)
                     /locus_tag="ACL3F5_001717"
     CDS             complement(200..2458)
                     /locus_tag="ACL3F5_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0515476.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATPLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2687..2917)
                     /locus_tag="ACL3F5_001718"
     CDS             complement(2687..2917)
                     /locus_tag="ACL3F5_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0515477.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3107..3790
                     /locus_tag="ACL3F5_001719"
     CDS             3107..3790
                     /locus_tag="ACL3F5_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0515478.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3790..4524
                     /locus_tag="ACL3F5_001720"
     CDS             3790..4524
                     /locus_tag="ACL3F5_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0515479.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4678..5535
                     /locus_tag="ACL3F5_001721"
     CDS             4678..5535
                     /locus_tag="ACL3F5_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0515480.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5678..6550
                     /locus_tag="ACL3F5_001722"
     CDS             5678..6550
                     /locus_tag="ACL3F5_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0515481.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3F5_001723"
     CDS             6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3F5_001723"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0515482.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7529..8740
                     /locus_tag="ACL3F5_001724"
     CDS             7529..8740
                     /locus_tag="ACL3F5_001724"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0515483.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGESGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8742..9284
                     /locus_tag="ACL3F5_001725"
     CDS             8742..9284
                     /locus_tag="ACL3F5_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGR0515484.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYLFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9300..10109
                     /locus_tag="ACL3F5_001726"
     CDS             9300..10109
                     /locus_tag="ACL3F5_001726"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0515485.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10585..10980
                     /locus_tag="ACL3F5_001727"
     CDS             10585..10980
                     /locus_tag="ACL3F5_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGR0515486.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10990..11565
                     /locus_tag="ACL3F5_001728"
     CDS             10990..11565
                     /locus_tag="ACL3F5_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0515487.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11590..12102
                     /locus_tag="ACL3F5_001729"
     CDS             11590..12102
                     /locus_tag="ACL3F5_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGR0515488.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3603 a         2233 c         2769 g         3594 t
ORIGIN      
        1 agattgaaat aagatgagaa caaatcgatt gggaaagtaa aattaatttc tataaatgtt
       61 ttagcaattg tttcgtacta tttcagattc agtctactat atatcataat ggacaaaggg
      121 caagctgtca agaaattaca gttattttag taaaaaaaga agcagaaaaa tttcattttc
      181 tactcctttt ctataggatt tatttttctt tttcagaact tttaacttca gcttttttgg
      241 cagatttaat ctgaatgttt cccttgctag tcataactgc tttgagatct ttttcgcttg
      301 gattttcaag gtagtagtca gtgattgtgt cctcaatata gtcttgaata gtccgacgaa
      361 gtgggcgtgc tcccattttt ggatcataac ctaggtcaac caacttttcc ttgaccttat
      421 cagttacatc caaacgaatg ttgttgctag agaggcgctt gttaacatct gctagcatga
      481 gctcgacaat ctgaaggagg ttatccttgc tgagagcctt aaattcgata atgccatcaa
      541 aacggttcat aaactctggg ctaaagaagt taccgagttc accgaggaca gaattggtac
      601 gtccttctct agcagcacca aatccaacgc tagcttcggt ctttcctgta cctgcatttg
      661 aggtcatgat aatgatggca tccttgaagc taacggtgcg tccttgcccg tctgtcaaac
      721 gaccatcgtc caagacttga agaaacatgt gcataacatc tgggtgagct ttttccactt
      781 catcgagaag gatgagagaa tatggattgt ggcgaacttt ttcagttaat tgaccagcct
      841 catcatagcc aacataacct ggaggggcgc cgaccaactt agccacacta tgtttttcca
      901 tgtattcact catatcaaag cgaatcatac tatcagcaga accaaaaagt tcgatagcca
      961 gttgtttgga aagttctgtc ttaccgacac cagttggccc aacgaagagg aagcttccga
     1021 ttgggcggtt aggggtacca agtccgacac gattacggcg aatagccttg gcaatcttat
     1081 cgactgcatc atcttggcca ataacatgag acttgagatc ttcggctaga tggatgagtt
     1141 gagattgttc tttctctttc aaatcaccaa cagggatatt ggttttctgc tcgataatgt
     1201 gctcaatagt tttctcgctg atgataggag tatcctggtc tgtgatcttt ttcttttgca
     1261 tttccttata cttggcaatc tggtcgcgga agtaggccgc cttctcaaaa tcttcttctc
     1321 gtgtagcttg agacttgaga ttttcagcct caatcaagcg ctgatcaatt actttaggat
     1381 ccacaaaatt caaggtcaag ttcatcttag aaccagcttc atctaggagg tcaatggcct
     1441 tgtcaggcaa gaagcgatct tggatgtagc gattggaaag agttgcagct gcttcaatcg
     1501 cagcatctgt atattgaacg tggtggtaat cttcgtattt cttttgaatc cctttgagaa
     1561 tagtgattgt ttcgtccacc gttggttcat cgactttaac aggctgcata cgacgctcga
     1621 gggcagcatc cttttcaatg atacggtatt cattgagggg agtagcaccg actagttgca
     1681 gttctccacg agcaagggct ggcttgagga tatttcctgc gtccatatta ccatcactcg
     1741 cagaaccagc accaacaatt tcatggattt catcgataaa gaggatgatg tcttcacgtt
     1801 tgcgaatttc ttccatgagt ttttgcatgc gttcttcaaa ttgtcctcga atccccgttc
     1861 cttgaactaa gctaaccaca tccagacgga tgacttgttt accttggagt ttatgtggca
     1921 catcgccatc gacaattttc tgagctagac cttcgacaac ggccgttttt ccgacaccag
     1981 gttcaccgat aaggacagga ttattcttgg ttctacgatt gagaatctcg atgacacgga
     2041 taatctcatc gtcgcgccca ataacggggt caatgtctcc acgacgggca atttcagtta
     2101 cattaatacc aaattcttcc agcaggcctt tttcttggct aggtggcgga gtttgagcag
     2161 atccacgatt ttgggaacca taaccgccgt ttccaccgta acctccacct gattgggttg
     2221 ggggaatagg aggagtattg ctagaaggtc tgaaattgtt tagatcattg aagaaatcac
     2281 caaagggatc gaagtcacga ttgttcagat ccgtcatacc tttgaagagg ctattgttag
     2341 gatctgtttt gataatctta tagcagtttt gacagaggtc aatttgtttt tgttttccat
     2401 tgagattggt gtaaagatga attgttgagt cgttaatttt acagttttga caaagcatac
     2461 atctacctca tttctttctt tagcctgact tgtttaaagg tcaaaaatag tcaaattcta
     2521 tactctcatt ataacaggat tggggtgtaa agcaagtaaa aagattgaag ctttgagaag
     2581 ttgttacaat gaaaattttt gtgaatttgg actataaaaa aatcctattt gtgagacaaa
     2641 aaggatttta cttagacatg cagggacaat cccagcttgt tttagattag tagagaagtt
     2701 cgtaaatttc cattgcgatt aagtcaatgc tatcaaacgt atacgtttcg cgatcttcta
     2761 cgtcacgaag ggtaaagatt gggccgtttt cttcgtcgtg gctgtacgca acttctgcaa
     2821 caacaactcc ttcgcgttca aaattacgtt ttaaatttcc gccatcgttt gccattgctt
     2881 caaggcggtt gatgattcta accaaatgtg attccatttt gattctcctt catttcttat
     2941 cgttactatt ttaccataaa ggaggccaac ttgactagaa aaaactaaga tttctcgcta
     3001 attctgctag tttaaagatt tttaaataaa ttggataaaa aatttaaatt ttaattcaaa
     3061 acatgttata atcatacagt attctatttt agaaagcagt gtgactatga atttttcttt
     3121 tttacctaag tatttacctt attttaacta tggggctgtt gtgacgattc ttatttctat
     3181 ctgtgttatc tttttgggaa ctattttggg tgttgtcttg gcttttgggc aacgttcaaa
     3241 gtttaaaccg cttgtttggt tggccaactt gtacgtttgg attttccgtg ggacaccgat
     3301 gatggttcaa attatgattg cctttgctct tatgcatatc aatgctccga ctattcagat
     3361 tggaatttta ggtgttgatt tttcgcgtct gattccaggg attttgatta tctctatgaa
     3421 tagtggtgct tatgtttcgg agactgttcg tgccggaatc aatgcggttc caaaaggtca
     3481 gctagaggcg gcttattcgc tagggattcg tcctaaaaat gcgatgcgtt atgtgatttt
     3541 gccacaagca gtcaaaaata tcttgccagc attggggaac gaatttatca ccattatcaa
     3601 ggacagctcc ctcttatcag ctattggggt catggagttg tggaatgggg ctacaacagt
     3661 ttctacaaca acctatctac ctttaacacc acttttattt gcagcatttt actacttgat
     3721 tatgacctct attctgacag tagccttgaa agcttttgaa aaacatatgg gacaaggaga
     3781 taagaaataa tgacagaaac cttgataaaa attgaaaatt tacataaatc ttttggaaag
     3841 aatgaagtat tgaagggcat caacctcgag attaaaagag gagaagttgt cgttatcatc
     3901 ggtccttcag ggagtgggaa atctaccttg cttcgctcta tgaatttgtt ggaggaagca
     3961 accaagggga aggttatctt tgagggagtc gatattacgg acaagaagaa tgacctgttt
     4021 gccatgcgtg agaagatggg catggttttc caacaattta acctctttcc taatatgact
     4081 gtgattgaaa atattacctt gtcacctatc aagaccaaag gtgaaagcag ggaagttgct
     4141 gagaagagag cccaagagct tttggaaaaa gttggtttgc cagataaggc agacgcttat
     4201 ccacagagtc tgtcgggtgg gcagcaacaa cggattgcca tcgcgcgtgg gttggctatg
     4261 gaaccagatg ttttgctctt tgacgaacca acttcagcct tggatcctga aatggtaggt
     4321 gaggtattgg ctgttatgca agaccttgcc aagtcaggga tgactatggt tatcgtaaca
     4381 catgagatgg gatttgcccg tgaggtggca gatcgtgtta tctttatggc agacggtgtg
     4441 gttgttgaag atgggacacc tgagcagatt tttgaacaaa cccaagaaca acggactaaa
     4501 gatttcttga gtaaggtttt ataatctatt ttaaaatttc aagacaagat tagtgaaaag
     4561 ttcaaccaga gctttttctt atagtttgaa actataggat aacctaggaa agaagtgtta
     4621 gagggcacta gcagtttttg gtataatgga agatatttga aagaaaagag aagtgatatg
     4681 acacagatta ttgatgggaa agctttagcg gccaaattgc aggggcagtt ggctgaaaag
     4741 actgcaaaat taaaggaaga aacagctcta gtgcctggtt tggtagtgat tttggttggg
     4801 gataatccag ccagccaagt ctacgttcgc aacaaggaga ggtcagctct tgcggctggt
     4861 tcccgtagcg aagtagtgcg agttccagag accattactc aagaggaatt gttagacctg
     4921 attgctaaat ataatcagga tccagcttgg catgggattt tggtccagtt gccattacca
     4981 aaacatatcg atgaagaggc ggttttatta gccattgacc cagaaaagga tgtggatggt
     5041 ttccatcccc taaacatggg acgtctttgg tctggacatc cagtcatgat tccctcgaca
     5101 cctgcaggaa ttatggaaat gtttcatgaa tatgggattg acttggaagg taaaaatgcg
     5161 gtcgtaatcg gtcgttcaaa tatcgttgga aaacctatgg ctcagcttct tttggctaaa
     5221 aatgcgacag taaccttgac ccactcacga actcataatc ttgccaaggt ggctgctaaa
     5281 gcagatattc ttgtagtcgc aatcggccgc gccaagtttg tgactgctga ctttgtcaaa
     5341 ccaggtgcgg ttgtcattga cgttgggatg aaccgagatg aaaatgggaa gctctgtgga
     5401 gatgttgatt atgaggcagt tgcaccactt gctagccata tcacgccagt ccctggaggt
     5461 gtcggtccta tgaccattac catgctgatg gagcaaactt atcaagcagc acttcggaca
     5521 ttggatagaa aataagagaa acattcgatt aatagagcgt attttctata gctatatcta
     5581 agaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgcct
     5641 cctttttgtt gtataataaa agtgagaggg aaaaaggatg aaagtgatta atcaaacctt
     5701 actagaaaaa gttattattg aacgttctcg ttcaagtcac aaaggagatt atggtcgtct
     5761 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5821 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5881 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     5941 gcaattggag aaggcagaag ttgtcttgtt ggggcctggt ttacgagacg atgcttctgg
     6001 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6061 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6121 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6181 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6241 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6301 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6361 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6421 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6481 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gatagggtaa gcaaagataa
     6541 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6601 cgcctgcttt aaggctaaac tagacatatc aaagttaaga gtttgttttt gtaactggaa
     6661 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6721 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6781 aaaaagcggt ttcatagtaa aataagaatt gagaatgatg gaggtaaatc ggtggaaaat
     6841 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6901 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     6961 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7021 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7081 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7141 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7201 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7261 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7321 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7381 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7441 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7501 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7561 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7621 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgttcc
     7681 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7741 agctgaaagc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7801 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7861 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     7921 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     7981 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8041 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8101 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8161 atcaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8221 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8281 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8341 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8401 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8461 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8521 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8581 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8641 tccagtagga cattttgcgg atatttcagc gactgttgcc gataactttg gtgtggaaac
     8701 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8761 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag
     8821 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
     8881 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     8941 attatctatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9001 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9061 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9121 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9181 agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9241 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
     9301 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
     9361 cccctgagtt cggtctaatc cttgggtcag gacttggaga attggcagaa gaaatcgaaa
     9421 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
     9481 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaaggtc
     9541 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
     9601 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc
     9661 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
     9721 gtgaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag
     9781 aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg
     9841 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
     9901 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
     9961 ctggcttgaa agttctggga atttcatgta tcactaactt tgcggctggt ttccaagaag
    10021 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    10081 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaagggga agtgcctctg
    10141 tgttttcagg attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt
    10201 cttcctgctc ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc
    10261 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc agactagtat
    10321 gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca
    10381 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    10441 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    10501 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    10561 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    10621 aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg
    10681 cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca
    10741 gagccagctc aagcggatga tatccgcaag gttgttgggg aattagccaa ggatataagt
    10801 attactaagt tgtatatgac aggtcattct cttggaggct acctagctca gattgcagcg
    10861 gttgaagatt accaaaaata tcctgatttt tataaccatg tattgaggaa agtgacaact
    10921 ttcagtgctc ctaaagtgat tacttccaga actgtttggg atgctaagaa tggtttctga
    10981 gatgttggtt tggaaagtcg taaattagct gttagtggaa aaattaagca ttatgtggtt
    11041 gataatgaca atgttgtgac tcccttgatt cataataatc gtgatattgt tacatttaca
    11101 ggtaattcac gctttaaaca ccgttctcgt ggctattttg aaagtccaat gaatgatatt
    11161 cctaacttta atattggtaa acaagctacc ttggataaac atggttatcg tgatccgaaa
    11221 ttggataaag cgcgattctt taagaaacag gctctacctc aatcttctag tcaaccaagc
    11281 gctgaaccaa tggaaaatat tgccttagga aaacaggtta ctcaaagttc gacagctttc
    11341 ggaggagatg ctagaagagc tgtggatggc aaagtcgatg gtaactatgg tcacaattct
    11401 gtcactcata caaacttcca atctaagcct tggtggcaag tagatttggc taaagaagaa
    11461 accattcgcc aaatcaatat ttacaaccga acagacactg cccaggatag attggcaaac
    11521 tttgatgtca ttcttttaga cggttctggt aaagaaattg agtgaaaacg tataatatct
    11581 cctaaagatg tgtcagcaca aattacgatt aaccataaaa aagcgcgcta tgttcggatt
    11641 gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg ctttatagct
    11701 acgaatgctg aaacggcgac acaagtttct aagccagttc aaccaatcag tcagactcct
    11761 gtgaaggata aaacattgac aattcaacac agtggagctt acattgcccg ctactccata
    11821 acttgggaag aagttccagt agataaagat ggaaaccaag ttgttcgtag tcattcttgg
    11881 gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat caaagaaaat
    11941 atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa tagatggcaa
    12001 acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac ccattggggt
    12061 acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg tacaatgaca
    12121 gttagtttgt ctagtttata agaaagtact acctgagctt gaatagaact caggtagctc
    12181 tctgtgaaag aacaaaatt
//
LOCUS       DBEJJE010000053        11881 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEJJE010000053 DBEJJE010000000
VERSION     DBEJJE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.53"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..209
                     /locus_tag="ACL3F5_001730"
     CDS             <1..209
                     /locus_tag="ACL3F5_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515489.1"
                     /translation="RKSSKLKPLTVEDKACNHALSKERSKVENIFAKVKTFKMFSTTY
                     RNHRKRFGLRMNLSVGIINHELGF"
     gene            359..613
                     /gene="blpM"
                     /locus_tag="ACL3F5_001731"
     CDS             359..613
                     /gene="blpM"
                     /locus_tag="ACL3F5_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGR0515490.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            629..832
                     /gene="blpN"
                     /locus_tag="ACL3F5_001732"
     CDS             629..832
                     /gene="blpN"
                     /locus_tag="ACL3F5_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGR0515491.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1076..1225
                     /gene="blpO"
                     /locus_tag="ACL3F5_001733"
     CDS             1076..1225
                     /gene="blpO"
                     /locus_tag="ACL3F5_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0515492.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1329..1448
                     /locus_tag="ACL3F5_001734"
     CDS             1329..1448
                     /locus_tag="ACL3F5_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0515493.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2234..2617
                     /locus_tag="ACL3F5_001735"
     CDS             2234..2617
                     /locus_tag="ACL3F5_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0515494.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2669..3358
                     /locus_tag="ACL3F5_001736"
     CDS             2669..3358
                     /locus_tag="ACL3F5_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0515495.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3400..3633
                     /gene="blpZ"
                     /locus_tag="ACL3F5_001737"
     CDS             3400..3633
                     /gene="blpZ"
                     /locus_tag="ACL3F5_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0515496.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3784..4395
                     /locus_tag="ACL3F5_001738"
     CDS             3784..4395
                     /locus_tag="ACL3F5_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0515497.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4556..5350
                     /gene="ccrZ"
                     /locus_tag="ACL3F5_001739"
     CDS             4556..5350
                     /gene="ccrZ"
                     /locus_tag="ACL3F5_001739"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0515498.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5347..5982
                     /gene="trmB"
                     /locus_tag="ACL3F5_001740"
     CDS             5347..5982
                     /gene="trmB"
                     /locus_tag="ACL3F5_001740"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0515499.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6109..6588
                     /gene="rimP"
                     /locus_tag="ACL3F5_001741"
     CDS             6109..6588
                     /gene="rimP"
                     /locus_tag="ACL3F5_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0515500.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6632..7768
                     /gene="nusA"
                     /locus_tag="ACL3F5_001742"
     CDS             6632..7768
                     /gene="nusA"
                     /locus_tag="ACL3F5_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0515501.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7790..8083
                     /locus_tag="ACL3F5_001743"
     CDS             7790..8083
                     /locus_tag="ACL3F5_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0515502.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8076..8375
                     /locus_tag="ACL3F5_001744"
     CDS             8076..8375
                     /locus_tag="ACL3F5_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0515503.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8392..11184
                     /gene="infB"
                     /locus_tag="ACL3F5_001745"
     CDS             8392..11184
                     /gene="infB"
                     /locus_tag="ACL3F5_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0515504.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11435..11785
                     /gene="rbfA"
                     /locus_tag="ACL3F5_001746"
     CDS             11435..11785
                     /gene="rbfA"
                     /locus_tag="ACL3F5_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0515505.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3660 a         2070 c         2694 g         3457 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aagccgctaa cagttgaaga taaagcctgt aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggact acgaatgaat ttgagtgttg
      181 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctaatgta atttttgcaa
      241 ttcaagacgt ttcgatgact attcaagatc tggatgaaaa attttaaaaa acgatgatat
      301 actaaacttg tcaaagttac aacaagacaa aaattaaaaa taaaaaagag tatttgtcat
      361 ggatacaaaa attatggaac aatttcatga aatggatata actatgttat ctagtattga
      421 aggaggcaag aataattggc aaactaatgt cttagaaggt ggtggtgctg cttttggtgg
      481 ctgggggcta gggacagcta tttgtgctgc gagtggtgtt ggagcaccat ttatgggagc
      541 atgtggatac ataggagcta aatttggtgt ggatctttgg gcaggagtaa caggggcaac
      601 gggtggattt taataaaagg agacttgtat gaatacttat tgtaatataa atgaaacaat
      661 gctgagtgag gtttatggag gtaattccgg aggagcagct gtagttgctg ctttaggttg
      721 tgcagcgggt ggagtgaaat atgggagact tctaggacca tggggcgctg caataggagg
      781 aattggagga gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa
      841 gctaaatttt atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat
      901 ttatctatcc ataagtatct ccgataaaaa acaaaagact attgaattaa catcattgaa
      961 ttgttttgtc atattatttc taatctatga taaattaatt tttctcttta ttgcctatgt
     1021 ttttttgata atttttatat taaacttgtt ccgtaactga aaagtgatat actatatgga
     1081 tacaaaaatg atgtcacaat ttgcagttat ggataatgaa atgcttgctt gcgttgaagg
     1141 tggagatatt gattggggaa gaaaaattag ttgtgcagca ggggttgcat atggcgcaat
     1201 tgatgggtgt gcaacaacgg tttgacattt ctattgggac catttgctat aggaataggt
     1261 gtaactggtg ctgcaggtgg agctatactt ggaggtgtag cctatgcagc aatatgttgg
     1321 tggtaattat ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt
     1381 atatggatga cttaattaga aaaatatttt caaaatcttc caaaaaggat acggatagta
     1441 ctctctaaaa aataaatttc tcccctgtat ttgctagctt aatttacagg ggagtttctt
     1501 taatattgtt tcgcctgtca aaatgatatg tgatagcagg atgaaaagtc tacaaacaag
     1561 ttggtatcaa tacaatataa agaggaaagt atgtttttaa tgcttacttt ttaaattttt
     1621 taacaattca agatgtttcg atgacaattc aagatttgga tgaaaaattt taaaaaacaa
     1681 tgatatacta aacttgtcaa agttgcaacg ggtgctgcta cattatgtta aaaatcgctc
     1741 ttgattgata agttggattt gttaggaaag gagtaaataa ttatggataa gaaaaagata
     1801 gtttcgacta taatatgtat agtatttctt gtagtgtcag tagataattt ttttagagac
     1861 ttaaccccgt tactgttcat tttaaatatt attggcctgt cttgcttttc agtgctaaca
     1921 tacattaaca taaaagagat actcttaaat ataagtaaat gatgatttgg ttagtcctag
     1981 aaccaatcaa cttatgttta tcggcttggc agattttatg tttgtcattt gtttgtatag
     2041 aggtatttca gaaacagaat tctatcaaca actaatcgct tatataggtg tattctctgc
     2101 ttgtttatca cgcttctgct catgtggggc ttgaagtatt ataaaaagta gctttctatc
     2161 cttttctgac aggatatttg agtagaaggc tctattaaat tgttagtgaa ataaatgaat
     2221 ggaggtattt aatatgaaat acagattatt ttttgttatt ttcttgagta gtgtgttgga
     2281 tattctttta gggacatttt tacaaatctc tatcgtatct attgggtggc ttgttcttta
     2341 cagtggtttg tttgaagcag gagttttcct tcttgctaat aaaggggtgg cggtaaaaat
     2401 caaggaagta gatattcgaa atcgctttaa atttattttt ggaaaaacct tatggtttca
     2461 aattcttttg ctcatctttt tgataatcaa actttatctt ggtttggatg cgaggttgat
     2521 tttattctat ggacatattt tcattgtctt taatgcctta atgtatctat tatctagtag
     2581 tcaggttagc cttaaaaaaa acaaactgtc ttcttaatct tacagcagta gagcctgaca
     2641 aggtgaggtc atagtaggga ggatttctat gaaaaagtat caacttctat tcaaaataag
     2701 tgcagtcttc tcttacttat ttttcgtatt tggtctttct cagctgacgc ttatcgtcca
     2761 aaactattgg caattttctt ctcagatagg caatttattc tggattcaaa atatcttgag
     2821 tttacttttt attggagtca tgattgtggt tcttgttaag acaggccatg gttatctctt
     2881 ccgcattcca agaaaaaaat ggctttggta ttcgattttg acagtattag tggtagtgtt
     2941 acagatctct tttaacgttc agacagctaa acatgttcag tcaactgcgg aaggttgggc
     3001 tgtattgatt ggttatagtg ggactaactt tgcagagcta ggtatttata tagccctgtt
     3061 ctttctggtt ccactgatgg aagaattgat ttatagagga ttactgcaac atgctttctt
     3121 taagcattcg cgatttggcc ttgatttgct tcttccttcc attttgtttg ctcttcctca
     3181 ttttttgagt ctgcctagtc tgttagatat cttcgtcttt gcaacatttg gaatcatctt
     3241 tgccggtttg acccgctata ccaagagtat ttatccatcc tatgcggtgc atgtgatcaa
     3301 taatattgta gcgaccttcc cgtttttgct cacttttcta catagggtct tggggtaaaa
     3361 aaacaaaagg cttgcttttc agccatagag gaggtcatca tgtataaaca cttatttttc
     3421 ctagattcca aaactttaga tcggttgaca ccctatattc tagtcttggc ttctgacacc
     3481 attgctttta atgtttttgt gctaaccttt gtatctgcgg tggtttttaa tttcctaaat
     3541 tccatgctag ctttaatggc tatattcata ggggctggct atgtggtcgg attttggtta
     3601 ctaatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
     3661 acggcaaggc gacgttgacg tggtttgaat ttgattttca ttgagtataa aatggtttgt
     3721 tttggaaagg ctagaactaa agaatgacgt gtaggaagtc tgtttgttga ggaggataat
     3781 tttatggagt tttttgataa atttcatgcc ttgtgttttg gatttttagt actaataatt
     3841 gtcattacag ttccttatac gattaaccat gggggttttt ttcaaaatga atctgcattg
     3901 attcttgtaa gtcttcttgt aacctcgctg agtgttgctt atgctagaaa gtttgaaatg
     3961 atttcttttg ggatgttaag caagaaacaa cttttgcttt tcattgcaat ctttcttcta
     4021 agtgtacttg agacgctggt ttatattcat ttcttcgctg tttcttctgg ctcaggggtc
     4081 caacacttgg cggaagtcag cagaggaatt tccctgtctt tgattttaac tacctcagtt
     4141 tttggcccca tccaggagga actcattttc agaggacttc ttcaaggtgc ggtttttgac
     4201 aattcttggt tagggcttgt gctaacttcc tctctctttt ctttcatgca tggaccttct
     4261 aatgtccctt cgtttatttt ttatctactt gggggtttgt tgctgggctt tgcttataaa
     4321 aagagtcaaa acctatgggt ttctactcta gtccatatgc tttacaacag ttggccactc
     4381 ttatattatt tataaaaatt atgaaaaggt aagcagaaga cggtgcttac ctttttcaag
     4441 ctataatgat acccaagcca atccagaggc ttttctttga gaatcgggtt agagtggttg
     4501 acgaataggc caaaaactag tagaatagta aggaaacttt atacggagga aagaaatgga
     4561 tttgggtgat aatgagctaa cactgactcc catacctggg aaaagtggca aggcttatat
     4621 gggtagctat cctgatggga agcgcatctt tgtaaaaatg aacacctctc caatcctacc
     4681 tggtctagct agagaacaaa ttgctccaca attattatgg agtcgtcgtt tggcagatgg
     4741 gcgtgatatg tgtgctcaag aatggttgac aggcaagata ttgaccccct atgatatgaa
     4801 tcgtaagcaa atcgtcaata ttttaacccg tcttcatcgc tcacgtccgt tgatgacaca
     4861 attgagtcgt ttgggctatg ccatggaaac acctgtagat ttactacagt cttggcagga
     4921 aacggctcca gatgctttgc gtaaaaatca ttttatcagt gaagtgatgg ctgatttacg
     4981 tcagactatt ccaggattta gagaggacca tgcgaccatt gtccatggag atgtacgaca
     5041 tagtaattgg attgagacag atagtggctt gatttattta gtagattggg attcggttcg
     5101 cttgaccgat cgcatgtttg atgtggccca tatgctctgc cattatattt cagaacatca
     5161 gtggaaggaa tggttgacct actacggtta caagtacaat caaacggtat taagtaaatt
     5221 gtattggtat ggtcaattgt cttatttgag tcagatttcc aagtattata tgaaccaaga
     5281 tttagaaaat gtcaatcggg agattcatgg tttgcgtcat ttccgagaca agtatggaaa
     5341 gagaagatga gagttagaaa tcgtaaaggg gcaacagaat tactagaggc aaatccccag
     5401 tatgtggtcc tcaatccctt ggaagccaag gcaaaatggc gggacttgtt tggcaatgat
     5461 aatcccattc atgtggaagt tggaagtgga aagggtgcct ttgtttcagg tatggccaag
     5521 caaaaccctg acatcaacta tatcgggatt gatattcaaa agtctgtttt gagctacgct
     5581 ttggacaagg tgcttgaagt tggagtgcct aacatcaagc tcttgtgggt agatggttct
     5641 gacttgactg actactttga agacggtgag attgatcgct tgtatctgaa cttttcagat
     5701 ccatggccga aaaaacgcca tgaaaagcgt cgtttgacct acaagacctt tttggatacc
     5761 ttcaaacgta tcttgcctga aaatggagaa attcatttca agacggataa ccgtggcttg
     5821 tttgagtaca gtttagtgag cttttctcaa tatggcatga aactcaatgg tgtctggcta
     5881 gatttgcatg ccagtgattt tgaaggcaat gtcatgacag aatacgagca aaaattctca
     5941 aacaaggggc aagttatcta ccgagttgag gcagaatttt aagagatagc ctaaaattag
     6001 gctgtacaag tgcttttgct ttacataagt tggcaaacgt gctatactaa gggtaagaat
     6061 atgagaaaga gaggcgggga aatatcttcg cctcttgctt atgaggaggt ggacgcaatc
     6121 gcaacaatcg tagaattagt cagagaagtt gtagaacctg tcatagaagc tccttttgaa
     6181 ctcgtggata tcgagtatgg aaagattggc agtgacatga ttctcagtat ttttgtagat
     6241 aaacccgaag gaattacctt gaacgacacg gcagacttga cagaaatgat cagtcctgtc
     6301 ctagacacca tcaagccaga tcccttccca gaacaatatt tcctagaaat taccagtcca
     6361 ggtttggaac gtcctttgaa aaccaaggat gccgtcgctg gagcggttgg aaaatacatc
     6421 catgtcgggc tctaccaagc catcgataag caaaaggtct ttgaaggaac cttgttggcc
     6481 ttcgaagagg acgagttgac tatggaatat atggacaaga cgcgtaagaa aaccgtccaa
     6541 attccataca gtttagtatc aaaagcacgt ttagcagtta aattatagaa aaagaaagga
     6601 tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa gaaatgctag aggccttccg
     6661 cattttggaa gaagacaagg gaatcaaaaa agaagatatc atcgacgcag tagtagagtc
     6721 gcttcgttcc gcttatcgca gacgctatgg tcagtcagac agcgtagcta ttgacttcaa
     6781 cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa gttgttgatg aagtatttga
     6841 tagccgtttg gaaatcagct tgaaagatgc tcttgccatt aattcagctt atgaacttgg
     6901 agacaaaatc aagtttgaag aagcaccagc tgagtttggt cgtgtagcag cccaatctgc
     6961 caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt gccatcactt acaatactta
     7021 caaagaacat gagcaagaaa tcatgtctgg tacagtagaa cgctttgaca accgctttat
     7081 ctatgtcaac cttggtagca tcgaagccca attgtcaaaa caagaccaaa ttcctggaga
     7141 agtttttgct tctcatgatc gtatcgaagt ttatgtttac aaggttgaag acaaccctcg
     7201 tggtgtgaac gtctttgtta gccgtagcca tccagaaatg atcaaacgtt tgatggagca
     7261 agaaattcca gaagtttatg atggaactgt tgaaatcatg agcgtggctc gtgaagcagg
     7321 tgaccgtacg aaggttgctg ttcgtagcca caatccaaac gtggatgcta tcggtacaat
     7381 cgttggacgt ggtggtgcta atatcaagaa gattactagc aaattccacc cagctcgtta
     7441 cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat atcgatgtta tcgagtgggt
     7501 agcagatcca gctgaattta tctacaatgc catcgctcct gctgaggttg accaagttat
     7561 ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt ccagataaca agctttctct
     7621 tgccattggt cgtcgtggac aaaacgtgcg cttggcggct cacttgactg gttaccgtat
     7681 cgatatcaag tctgctagcg aatttgaagc catggaagac gctgcttcag tagagttgga
     7741 agtagaaaac gatactgtag aagaataaaa gctgctagag gagggaaaga tgaaaacaag
     7801 aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg attgataagc gtgatttgct
     7861 ccgcattgtc aagaacaagg aaggacaagt ctttattgat cctacgggca aggccaatgg
     7921 ccgcggcgct tatatcaaac tagacaatgc agaagcccta gaggcgaaaa agaagaaggt
     7981 ctttaaccgc agctttagca tggaagtgga agaaagcttt tatgacgagt tgatcgctta
     8041 tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa taagcaaaag ataagtaatc
     8101 tcttggggct tgctcagcga gcagggcgca tcatatcggg tgaagaattg gtggtcaagg
     8161 ccattcaaga cggcaaggcc aagttggtct ttctagctca tgatgctgga cccaatctga
     8221 ccaagaagat tcaagataaa agtcattatt atcaagtaga aattgtaacc gtgttttcaa
     8281 cactggaatt aagcatagca gtcgggaaat cgagaaaggt tttggctgta acagatgctg
     8341 gatttacaaa gaaaatgagg tctcttatgg aatagaagag gaggacatga tttgtctaag
     8401 aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa gtaaagaagt tgtagcgcgt
     8461 gcaaaagagt taggcttgga tgtgaaaagc cactcatcaa gtgtggaaga agctgtcgct
     8521 gcaaaaattg ctgccagctt taagcctgca gctgctccga aagtagaagc aaaacctgca
     8581 gcaccaaaag taagtgcaga aaagaaagcc gaaaaatctg agccagctaa accagctgta
     8641 gctaaggaag aggcaaaacc ggctgagcca gttgctccga aaacagaaaa agtagcagcg
     8701 aaaccgcaaa gtcgtaattt caaggctgag cgtgaagccc gtgctaaaga gcaggcagaa
     8761 cgacgcaagc aaaataaggg caataaccgt gaccaacaac aaaacggaaa ccgtcagaaa
     8821 aacgacggcc gtaatggtgg aaaacaaggt caaagcaacc gcgacaatcg tcgctttaat
     8881 gaccaagcta agaagcagca aggtcagcaa aaacgtagaa atgagcgccg tcagcaagag
     8941 gataaacgtt caaatcaagc ggctccacgt attgacttta aagcccgtgc agcagcccta
     9001 aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg aacgcttcaa gcagtatcag
     9061 gctgctaaag aagccttggc tcaagctaac aaacgcaagg aaccagagga aatctttgaa
     9121 gaagcggcta agttagctga acaagcacag caagttcaag cagtggttga agtcgtccct
     9181 gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac aagctcgacc agacaaaaat
     9241 cgtgacgatt atgatcatga agaagatggt cctagaaaac aacaaaagaa tcgaagtagt
     9301 caaaatcaag tgagaaatca aaagaatagt aactggaata acaacaaaaa gaacaaaaaa
     9361 ggcaataaca agaacaaccg taatcagact ccaaaacctg ttacggagcg taaattccat
     9421 gaattgccaa cagaatttga atatacagat ggtatgaccg ttgcggaaat cgcaaaacgt
     9481 atcaaacgtg aaccagctga aattgttaag aaacttttca tgatgggtgt catggccaca
     9541 caaaaccaat ccttggatgg ggaaacaatt gaactcctca tggtggatta cggtatcgaa
     9601 gcaaaacaaa aggttgaagt ggataatgct gacatcgaac gtttctttgt cgaagatggt
     9661 tatctcaatg aagatgaatt ggttgagcgt ccaccagttg ttactatcat gggacacgtt
     9721 gaccacggta aaacaaccct tttggatact cttcgtaact cacgtgttgc gacaggtgaa
     9781 gcaggtggta ttactcagca tatcggtgcc taccaaatcg tggaaaatgg taagaagatt
     9841 accttccttg atacaccagg acacgcggcc tttacatcaa tgcgtgcgcg tggtgcttct
     9901 gttaccgata ttacgatctt ggtcgtagcg gcagatgacg gggttatgcc tcagactatt
     9961 gaagccatca accactcaaa agcagctaac gttccaatca tcgtagctat taacaagatt
    10021 gataaaccag gtgctaaccc agaacgcgtt atcggtgaat tggcagagca tggtgtgatg
    10081 tcaaccgctt ggggtggaga ttctgaattt gttgaaatct cggctaaatt caaccaaaat
    10141 atcgaagaat tgttggaaac agtccttctt gtggctgaaa tccaagaact caaagcagac
    10201 ccaacagttc gtgcgatcgg tacggttatc gaagcgcgct tggataaagg aaaaggtgcg
    10261 gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc aagacccaat cgttgtcgga
    10321 aataccttcg gtcgtgtccg tgctatgacc aacgaccttg gtcgtcgtgt taaagttgct
    10381 ggaccatcaa caccagtctc tatcacaggt ttgaacgaag caccgatggc gggtgaccac
    10441 tttgccgttt acgaggatga aaaatctgcg cgtgcagcag gtgaagagcg tgccaaacgt
    10501 gccctcatga aacaacgtca agctacccaa cgtgttagcc ttgaaaacct ctttgatacc
    10561 cttaaagctg gggaactcaa atctgttaat gttatcatca aggccgatgt acaaggttct
    10621 gttgaagccc tttctgcctc acttcaaaag attgacgtgg aaggtgtcaa agtgactatc
    10681 gtccactcag cggtcggtgc tatcaacgaa tcagatgtga cccttgccga agcttcaaat
    10741 gcctttatcg ttggtttcaa cgtacgccct acaccacaag ctcgtcaaca agcagaagct
    10801 gacgatgtgg aaatccgtct tcacagcatt atctacaagg ttatcgaaga gatggaagaa
    10861 gctatgaaag ggatgcttga tccagaattt gaagaaaaag ttattggtga agcggttatc
    10921 cgtgaaacct tcaaggtgtc taaagtcgga actatcggtg gatttatggt tatcaacggt
    10981 aaggttgccc gtgactctaa agtccgtgtt atccgtgatg gtgtcgttat ctatgatggc
    11041 gaactcgcaa gcttgaaaca ctacaaagac gacgtgaaag aagtgacaaa cggtcgtgaa
    11101 ggtggattga tgatcgacgg ctacaatgat attaagatgg atgatgtgat tgaggcgtat
    11161 gtcatggaag aaatcaagag ataagatttt ttgctccttt cttaggtggt gagggacgca
    11221 agcaaaccga tggtttcatt gcttattttt gagcctaggg tctcaaaaat cccctgtgat
    11281 gggactgata aatcagttcc atcactttca ccacggcgaa agaagcagat gacttcaaat
    11341 tgaacttcgt ttcaatttaa actgaaaatc aagaagttta aaatagctag gtctgctggc
    11401 ctagcttttg gttcaaagta gagaaaggaa tatcatggca aatcatttcc gtacagatcg
    11461 tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg caaaagaaag tccgtgatcc
    11521 acgtgtccaa ggtgtgacca tcacagatgt tcagatgctg ggtgacttgt ctgttgccaa
    11581 ggtttattac accattttga gtaaccttgc ttcggataac caaaaagccc aaatcgggct
    11641 tgaaaaagca actggtacca tcaaacgtga acttggtcgc aatttgaaat tgtacaaaat
    11701 cccagatttg accttcgtca aagacgagtc catcgagtat ggaaacaaga ttgacgagat
    11761 gctacgcaat ctggataaga actaaagaag aggggttgcc cctctttttt ggtggaggaa
    11821 aataggttga atttgaaatg gaaaaatatt cttttaaaat atattgaaac tagaatagta
    11881 c
//
LOCUS       DBEJJE010000054        11767 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEJJE010000054 DBEJJE010000000
VERSION     DBEJJE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.54"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            192..2483
                     /gene="pcrA"
                     /locus_tag="ACL3F5_001747"
     CDS             192..2483
                     /gene="pcrA"
                     /locus_tag="ACL3F5_001747"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0515506.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2526..3206
                     /gene="radC"
                     /locus_tag="ACL3F5_001748"
     CDS             2526..3206
                     /gene="radC"
                     /locus_tag="ACL3F5_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0515507.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3203..3892)
                     /locus_tag="ACL3F5_001749"
     CDS             complement(3203..3892)
                     /locus_tag="ACL3F5_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0515508.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3910..4551)
                     /locus_tag="ACL3F5_001750"
     CDS             complement(3910..4551)
                     /locus_tag="ACL3F5_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0515509.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4634..4849)
                     /locus_tag="ACL3F5_001751"
                     /pseudo
     CDS             complement(4634..4849)
                     /locus_tag="ACL3F5_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
     gene            complement(4857..5204)
                     /locus_tag="ACL3F5_001752"
     CDS             complement(4857..5204)
                     /locus_tag="ACL3F5_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0515510.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5209..6324)
                     /locus_tag="ACL3F5_001753"
     CDS             complement(5209..6324)
                     /locus_tag="ACL3F5_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0515511.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEANNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKENLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6334..7293)
                     /locus_tag="ACL3F5_001754"
     CDS             complement(6334..7293)
                     /locus_tag="ACL3F5_001754"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0515512.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7406..7975)
                     /locus_tag="ACL3F5_001755"
     CDS             complement(7406..7975)
                     /locus_tag="ACL3F5_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0515513.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8103..8774
                     /locus_tag="ACL3F5_001756"
     CDS             8103..8774
                     /locus_tag="ACL3F5_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0515514.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8758..9576
                     /locus_tag="ACL3F5_001757"
     CDS             8758..9576
                     /locus_tag="ACL3F5_001757"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0515515.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9573..10469
                     /locus_tag="ACL3F5_001758"
     CDS             9573..10469
                     /locus_tag="ACL3F5_001758"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0515516.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     DIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10513..11487
                     /gene="pta"
                     /locus_tag="ACL3F5_001759"
     CDS             10513..11487
                     /gene="pta"
                     /locus_tag="ACL3F5_001759"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0515517.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3416 a         2265 c         2542 g         3544 t
ORIGIN      
        1 gttttgcagg aagtctattg aggtattgag ctagtttatg aaaaaattgg gtgaaaagtc
       61 gagtgtttta gaaacccaca gtgtagtatt ctagtttcaa tctactatat tttgctactc
      121 cccgtaaagt ttctattttc cctgatttct gatataatag aaatattgac ttcaagagta
      181 aggaagagaa gatgaacgca ttattaaatg gaatgaatga ccgtcaggct gaggcggtgc
      241 aaacgacaga aggtcccttg ctaatcatgg caggggctgg ttctggaaag actcgtgttt
      301 taacccaccg tatcgcttat ttgattgatg aaaagctggt caatccttgg aatatcttgg
      361 ccattacctt taccaacaag gctgcgcgtg agatgaaaga gcgtgcttat agcctcaatc
      421 cagctactca ggactgtctg attgcgacct tccactccat gtgtgtgcgt attttgcgtc
      481 gcgatgcgga ccatattggc tacaatcgta attttacaat tgtggatcct ggtgaacagc
      541 gaacgctcat gaaacgtatt ctcaaacagt tgaacttgga tcctaaaaaa tggaatgaac
      601 gaactatttt ggggaccatt tccaatgcta agaatgattt gattgatgat gttgcttatg
      661 ctgcccaagc tggcgatatg tatacgcaaa ttgtggccca gtgttataca acctatcaaa
      721 aagaacttcg tcagtctgaa tccgttgact ttgatgattt gattatgctg accttgcgtc
      781 tctttgatca aaatcctgat gttttgacct actaccagca aaaattccaa tacatccacg
      841 ttgatgagta ccaagatacc aaccacgctc agtaccaatt ggtcaaactc ttggcttccc
      901 gttttaaaaa tatctgtgtg gttggggatg cggaccagtc tatctacggt tggcgtggtg
      961 ctgatatgca gaatatcttg gactttgaaa aggattaccc caaagctaag gttgttttgt
     1021 tggaggaaaa ttaccgctca accaaaacca ttctccaagc ggccaacgag gttattaaaa
     1081 ataataaaaa tcgccgtcct aaaaatctct ggactcaaaa cgctgatggg gagcaaatcg
     1141 tttactatcg tgccgatgat gagctggatg aggctgtatt tgtagccaga accatcgatg
     1201 aacttagtcg cagtcaaaac ttccttcata aggattttgc agttctctat cggactaatg
     1261 cccagtcccg tacaattgag gaagccctgc tcaagtctaa cattccttat accatggttg
     1321 gcggaaccaa attctacagc cgtaaggaaa ttcgcgatat tattgcttat ctcaacctta
     1381 ttgctaattt gagtgacaat attagttttg agcgtattat caacgagcct aaacgtggaa
     1441 ttggtccagg tacagttgag aaaatccgtg attttgcaaa tttgcaaaat atgtctatgc
     1501 tggatgcttc tgctaatatt atgttgtctg gtatcaaggg taaggcagcc caatctatct
     1561 gggattttgc caatatgatg cttgatttgc gggagcagct agaccactta agcattacag
     1621 agttggttga gtccgtccta gaaaaaacag gttatgtcga tattcttaac gcccaagcga
     1681 ctctagaaag caaggcacgg gttgaaaata tcgaagagtt tctttctgtt acgaagaact
     1741 ttgatgacac cacggatgtg acagaagagg aaactggtct ggacaaactg agtcgtttct
     1801 taaatgactt ggctttgatt gccgacacag attcaggtag tcaggagaca tcagaagtga
     1861 ccttgatgac cctgcatgct gccaaaggtc tcgaatttcc agttgtcttt ttgattggga
     1921 tggaagaaaa tgtctttcca cttagtcgtg cgactgaaga tccagatgaa ttagaagaag
     1981 agcgccgtct agcctatgta ggtatcacgc gtgcagagaa aattctctat ctgaccaatg
     2041 ccaactcacg cttgcttttt ggtcgtacca attataaccg tccgactcgt tttattaacg
     2101 aaatcagttc agacttgctt gagtatcaag gtctggctcg tcctgcaaat acaagcttta
     2161 aggcatcata tagcagtggt agtatttcct ttggtcaagg tatgagtttg gctcaggctc
     2221 ttcaagaccg taaacgcggt gctgccccaa aatcaatcca gtcaagcggt cttccatttg
     2281 gtcaatttac agctggcgca aaaccagcat ctagcgaggc aaattggtcc attggtgata
     2341 ttgctctcca caagaaatgg ggagagggaa ccgttctgga agtttcaggt agcggtgcta
     2401 ggcaggaatt gaaaatcaat ttcccagaag taggtttgaa aaaactttta gccagtgtgg
     2461 ctccaattga gaaaaaaatc taattttcca tccttctcac gaataataaa gtgaggagga
     2521 tttttatgta cagtatttca ttccaagaag attcactatt accaagagaa aggctggcca
     2581 aggaaggagt tgaagcgctt agtaaccaag agttgctagc tattttactc aggacaggaa
     2641 cacgtcaagc tagcgttttt gaaattgccc aaaaagtctt gaacaatctt tcaagcctaa
     2701 cggatttgaa aaaaatgacc ctgcaggaat tgcagagttt gtctggtatt gggcgtgtta
     2761 aggccataga attacaagct atgattgaac tggggcatcg tattcacaaa cacgagactc
     2821 ttgaaatgga aagtattctc agcagtcaaa agttggccaa gaagatgcag caggaattag
     2881 gggataaaaa acaagagcac ctggtggcac tctatctcaa tactcaaaat caaatcatcc
     2941 atcagcagac catttttatc gggtctgtaa ctcgtagtat cgctgaaccg cgagagattc
     3001 ttcactatgc aatcaagcat atggcgactt ctcttatctt ggtccacaat catccttcag
     3061 gagcggtagc gcctagccaa aatgatgatc atgtcactaa acttgttaaa gaagcctgcg
     3121 aactgatggg gattgttctc ttggaccatt tgattgtctc tcattctaat tactttagtt
     3181 atcgtgaaaa gacagattta atctaaagtt cattaacgac atagtcaaag agttttttat
     3241 ctttgggacg attttcaaaa agaagttctg gatgccattg gacaccgaga aaggcgacat
     3301 catccgtact catgacagcc tcaatgatac catctttagg atcatgagcc acaactttta
     3361 aatttggtgc taagtccttg atgctctggt ggtggaagga gttgatatga gagatttctc
     3421 catagatttc ttggagaacg gtatctggtt ctgtcaccaa gcgttgagtt gtgtactcaa
     3481 cagaagaatc ctgccaatgg tcttcgatat cttggtacaa agttccaccc atggcaacgt
     3541 taaagagttg ggtaccacgg cagacagaga aaatgggctt tttctgttta atagcttcct
     3601 tgatgagggc cagttcgaag atatctcttt gaaggtgata gtcatcgcta tcaatggttt
     3661 tgggttcgcc atagaatttt ggatcgacat tttgcccacc tgtcaagatg agcttgtcaa
     3721 tcaaactgat atagtggcag gccatttctt gatcaccaat cggtaggatg atgggaatcc
     3781 ctccagcatc tttaacgcct tcaacaaagc cttttgctgc gtagctcatc atgatgtcat
     3841 catctggatg agctttttcg tttcctgtaa tcccaataac tggttttttc ataaaatgat
     3901 tttcgctttc taatcctctt ttcgcatgaa gtagaggagg gtttggagtt cacttgtcaa
     3961 atcgacatac tgaacgacca cgtcttttgg taaatgcaga tggactggtg aaaaactgag
     4021 aattcctttc acaccagcat caaccaagag attagcaacc tcttgtgact tgacgctggg
     4081 aacagttagg atagcagtct tcacatcagc atccttgatt ttatccttga tctgagaaat
     4141 cccgtaaatg ggaatcccgt caggagtttg ggtaccgact tcaggatggt cgtctaggtc
     4201 aaaggccatg ataatcttca tcttgttacg ttcgtggaag cggtagtgga gaagggcatg
     4261 gcccatattt ccaataccaa ccagcatgac attggtaata gagttgtcat tgagcaaatc
     4321 ggcaaaaaat gtcattagtt ttttgacatc atagccaaaa ccacgacgac caagttcacc
     4381 aaaataggaa aaatcacgac gtacggtcgc tgaatcaata ccgatagcct ctgcaatttg
     4441 cttagagttg gcacgttcaa tcttttctgc atgaaatctc ttaaaaattc gatagtagag
     4501 agagagtctt tttgctgtag cttttggaat agcaaactgt ttatctttca caaaatcaca
     4561 acctttctat tcttctattt tatagaaaca ttgtgaaaaa atcaacaaaa ataagaaaaa
     4621 actaagaaaa atcttagttt tgatgtaaaa aatctgcatg agatagaaaa cggtagaggt
     4681 ctccgaccag accctgataa actttttagc ccctaaaagt cagagaagtc acataaagtg
     4741 tatctggtaa ggttacacat cctgacaaag tcaacatgag agcctcatga tcctcatact
     4801 tgagagtacg ctctacatga tagcagtcct tataggtcag ttcaaacatt ttggctctat
     4861 ctttccgatt ttgtaaagac accacgttct accaagctat ccatgaggaa gtagaatttt
     4921 tcctgatgaa tatggtggtc ttctgatttg aaaatatcaa ctagacgaag gccaaacttg
     4981 tcagtgatat tgattttagc ccctgtaagt tccttgttaa tgatgatttt gagttggaag
     5041 ccttcaccgc tgtttggcac tttttccaaa aggcgagtca gttcatagtt accaacctta
     5101 gtttcaaaaa aggtgttatc tttgagggtg aattttttaa cagaaggact aagagtgtaa
     5161 tcgtaacgac aattttttaa ctgaatgatt ttttcaaatg ccatatggct aacctccgat
     5221 aatttctttt aaggtttttg cgagggtttg taggtcttca acggtatttt gtggcgacaa
     5281 actgatgcga agggattcct tcaagcgttc tgaatttgcg ccatacatgg cttcaagaac
     5341 atggctggat tggacaacgc ctgcagtaca ggctgagcca gtagagattg aaattccagc
     5401 taaatctagc cgaaggagta agaggtcatt tttctgacca ggaaatccaa tattgagaac
     5461 ataagggaga tgatgttttc ctctattcaa gtaatactga atgccctcca gctctgccag
     5521 aaaggcagtt tctagatttt gtacatgttg aaaatgttct tcttgttttt ctaggttttc
     5581 ttttagggct gcaaccatgc ctacgatggc aggcagattt tcagttcctg cacgtttttt
     5641 ctgttcctgg tctccgccat gtagatagga atcaaagtcc atgctagatg cgtagagaaa
     5701 accgattccc ttaggaccat ggaatttgtg ggcagaagca gtgagaaaat caatgcccaa
     5761 ttcttctgaa tgaattggga ttttaccaat agcctgaact gcatcaacat gataggcagc
     5821 agggtgttgc ttgagtattt ggccaatttc agcgatgggc agtaggtttc ctgtctcatt
     5881 attggcaaac atggtagaaa ccaaaatcgt atcgtcacgt aaagcctttt gaatttgctg
     5941 ggctgtgatt tcttgatttt ctggctggat aatggttgct tcaaacccaa agtgttgaac
     6001 caagtaatca attgtttcaa ggacagcatg gtgctcgatg gcagttgtga tgatatgttt
     6061 tccttgttct tggtgacgaa gacagtagcc aatgatggta gtattattgg cttcagtccc
     6121 accagaagtg aaaaagatat gttgaggttt tgtccttagt aactgggcta gttcctgacg
     6181 ggcttctcgc aagagtttgc cagcttgacg accatgacca tgaatactag aaggatttcc
     6241 gtgggtttct tgcataacct tggtcatagc tgaaatagca actgctgaca taggagtcgt
     6301 tgcagcattg tccaaataaa tcaaagaatc accttatttc tttttattgt aggcaaagag
     6361 tgggctgact ggttttcttt cgtgaatacg gacgatagca tcgccaatta actcactagc
     6421 agtgatgtag catacatttt taggagtttt ttcttttgtt gctactgaat cagtcacaag
     6481 aatttcttta atattagtat tgtcaagaag ctcagcagct ccctcgacga agagaccgtg
     6541 gctagaaaca gcataaattt ctgtagctcc ttcacgttca acgattttag aagcttcaga
     6601 gaaggtacgt cctgtattta aaatatcatc aatcaagata gctttcttac cttcaacatc
     6661 accaataata taaccttcgt tacgagttgc atcgtcttga gggtaatcga taatggcgat
     6721 aggagcatca agatattcag ccaggctacg cgcacgtttg acacctgaat ttttagggct
     6781 aacgacaaca acatctgaac caagcaatcc tttatcgcag taatgttttg cgaatagggg
     6841 aacagtgaaa agattatcca ctggaatatc aaagaaacct tgaacctgaa cggcatgcaa
     6901 atcaagagtc aggatacgat caactccagc cttaaccagc atattggcaa ctagttttgc
     6961 tgtaagtggc tcacgaggac aagcaatgcg gtcttgacgt gcatagccaa aatatggaag
     7021 gacaacgttg atactgtggg cacttgcacg cacacaagca tcgaccatga ttaacaattc
     7081 cattaggtgg ttgttgacag ggaaacttgt tgattggatg atgtaaacat cataaccacg
     7141 gacactttct tcgatattta cttggatttc tccgtctgaa aattgacgtg atgatagttt
     7201 tccaagtggg acaccaacag cttgggcaat tttctgtgca atctcttggt tagagttgag
     7261 tgcgaaaagt ttcatgtttt ttctatctga cattatagac cgtcctctgt aaactttata
     7321 aatcctagtt atatttacct tacatatatg aactagggtt tgtgtatttt tatcttttct
     7381 attttaccaa aaaatggaga ttatttcagc tatttttcat acttttgaca aatcgaacca
     7441 attttgaagg agctttttga taggaaatct gatttttctc taaaaattgt cggaaatcct
     7501 gtttgccttg ctcatgattt tccacttcaa gctccaattc gtaatctgtt atatcaaagt
     7561 atcggctctg atccagtgcc atgagaccaa tagctgtttt catttcatag cgaagcgttg
     7621 ttagacaacc aagaacctgc cagttcttac tttggatacc atgtttcgcc aattcatcca
     7681 gtactagccc ttgaggaagt tcttccttac tcagatagtt ctcagcatct tttagttgca
     7741 atttttggtt gtattccatg tttccaacac tctgcgggac tttgagtgtc aactcagccc
     7801 agtcttcaaa ggttcgaatg cgcatagcga ctttcttttc tcgcagttca aaatcaggcg
     7861 tgtcgatgta gtaatttgtt tgaagaacag gagtgacacc tgtgaactgg tcttttagac
     7921 gattgtattc atcttttttc aatagtgttt tcaattcaat ttctaaatgt ttcatttttc
     7981 ttaccttttt ttatcgttga aagcggattt atggtataat aagcattgta tttattgtat
     8041 atgaatctgg agaaaaaatc aaagatattt ttgacggata atatgagaac aagggagaat
     8101 atatgacctt agaatgggaa gaatttctag atccttacat tcaagctgtt ggtgagttaa
     8161 agattaaact tcgtggtatt cgtaagcaat atcgtaagca aaataagcat tctccaattg
     8221 agtttgtgac cggtcgagtc aagccaattg agagcatcaa agaaaaaatg gctcgtcgtg
     8281 gcattactta tgcgaccttg gaacacgatt tgcaggatat tgctggctta cgtgtgatgg
     8341 ttcagtttgt agatgacgtc aaggaagtag tggatatttt gcacaagcgt caggatatgc
     8401 gaatcataca ggagcgagat tacattactc atagaaaagc atcaggctat cgttcctatc
     8461 atgtggtagt agaatatacg gttgatacca tcaatggagc taagactatt ttggcagaaa
     8521 ttcaaattcg tactttggcc atgaatttct gggcaacgat agaacattct ctcaactaca
     8581 agtaccaagg ggatttccca gatgagatta agaagcgact ggaaattaca gctagaatcg
     8641 cccatcagtt ggatgaagaa atgggtgaaa ttcgtgatga tatccaagaa gcccaggcac
     8701 tttttgatcc tttgagtaga aaattaaatg acggtgtagg aaacagtgac gatacagatg
     8761 aagaatacag gtaaacgaat tgatctgata gccaatagaa aaccgcagag tcaaagggtt
     8821 ttgtatgaat tgcgagatcg tttgaagaga aatcagttta tactcaatga taccaatccg
     8881 gatattgtca tttccattgg cggggatggt atgctcttgt cggcctttca taagtacgaa
     8941 aatcagcttg acaaggtccg ctttatcggt cttcatactg gacatttggg cttctataca
     9001 gattatcgtg attttgagtt ggacaagcta gtgactaatt tgcagctaga tactggggca
     9061 agggtttctt accctgttct gaatgtgaag gtctttcttg aaaatggtga agttaagatt
     9121 ttcagagcac tcaacgaagc cagcatccgc aggtctgatc gaaccatggt ggcagatatt
     9181 gtaataaatg gtgttccctt tgaacgtttt cgtggagacg ggctaacagt ttcgacaccg
     9241 actggtagta ctgcctataa caagtctctt ggcggtgctg ttttacaccc taccattgaa
     9301 gctttgcaat taacggaaat tgccagcctt aataatcgtg tttatcgaac actgggctct
     9361 tccattattg tgcctaagaa ggataagatt gaacttattc caacaagaaa cgattatcat
     9421 actatttcgg ttgacaatag cgtttattct ttccgtaata ttgagcgtat tgagtatcaa
     9481 atcgaccatc ataagattca ctttgtcgcg actcctagcc ataccagttt ctggaaccgt
     9541 gttaaggatg cctttatcgg tgaggtggat gaatgaggtt tgaatttatc gcagatgaac
     9601 atgtcaaggt taagaccttt ttaaaaaagc acgaggtttc taagggattg ctggccaaga
     9661 ttaagtttcg aggtggagct attctggtca ataatcaacc gcaaaatgca acgtatctat
     9721 tggacgttgg agactacgtt accattgaca ttcccgctga gaaaggcttt gaaaccttgg
     9781 aggctattga gcttccatta gatattctct atgaggatga ccactttcta gtcttgaata
     9841 aaccctatgg agtggcttct attcctagtg tcaatcactc taataccatt gccaatttta
     9901 tcaagggtta ctatgtcaag caaaattatg aaaatcagca ggttcacatt gttaccagac
     9961 tagataggga cacttctggc ttgatgctct ttgccaagca cggttatgcc catgcacgat
    10021 tagacaagca gttgcagaag aaatctatcg agaaacgcta ctttgctttg gttaagggag
    10081 atggacattt ggagccagaa ggggaaatta ttgctccgat tgcgcgtgat gaagactcca
    10141 ttattaccag acgggtggct aaaggtggaa aatatgccca tacttcctac aagattgtag
    10201 cttcttatgg aaatatccac ttggtcgaca ttcggctgca cactggtcga acccaccaaa
    10261 ttcgagtcca cttttctcat attggttttc ctttgttggg cgatgatttg tacggtggta
    10321 gtctggacga cggcatccaa cgtcaggccc tgcattgcca ttacctatcc ttttatcatc
    10381 catttttaga gcaagatttg cagttagaaa gtcccttgcc ggatgatttc agcaacctta
    10441 ttacccagtt atcaactaat actctataaa aactgtttca gagtataatt attatcttaa
    10501 aggagaaaac tcatggaagt ttttgaaagt ctcaaagcca accttgttgg taaaaatgct
    10561 cgtatcgttc tccctgaagg ggaagagcca cgtattcttc aagcgactaa acgtttggta
    10621 aaagaaacag aagtgattcc tgttttgtta ggaaatcctg aaaaaattaa aatttatctt
    10681 gaaattgaag ggatcatgga tggttatgag gtcatcgacc ctcaacatta tcctcaattt
    10741 gaagaaatgg tttctgcctt ggtggagcgt cgcaagggca aaatgactga agaagatgta
    10801 cgcaaggttt tggttgaaga tgtcaactac tttggtgtga tgttggttta cttgggcttg
    10861 gttgatggaa tggtgtcagg agcgattcac tcaacagctt caacagttcg tccagctcta
    10921 caaatcatca aaactcgtcc aaatgtaact cgtacttcag gagccttcct catggttcgt
    10981 ggtacggaac gttacctatt tggagactgt gccattaaca tcaatccaga tgcagaagcc
    11041 ttggctgaaa ttgccatcaa ctcagcaatc acagctaaga tgtttggcat cgaacctaaa
    11101 attgccatgt tgagctattc tactaaaggt tcagggtttg gtgaaagcgt tgataaggtc
    11161 gttgaagcaa ctaaaattgc tcacgacttg cgtcctgacc ttgaaatcga tggtgagttg
    11221 caatttgatg cagcctttgt tcctgaaact gcagctctga aagctcctgg aagtacggta
    11281 gctggtcaag caaatgtctt catcttccca ggtatcgagg caggaaatat cggttacaag
    11341 atggctgaac gcctgggtgg ctttgcggct gtaggacctg ttttgcaagg tttaaacaag
    11401 ccagttaatg atctttctcg tggatgtaat gcagatgatg tttacaagtt gaccctcatc
    11461 acagcagctc aagcagttca tcaatagtga aaactataaa gcgatatact atgctatact
    11521 gtagttatga aactatgtac gaaaagcact gccattaatt cctgagaact aaattactga
    11581 ttggtgtcaa aaaggaaaac ttccaagcga tgatatcctg tctatacacg acctatagaa
    11641 atctgtaata tgtatgtccg taaaacgata atttcccttt ttgattttaa atgagtatga
    11701 aaagagaatt ttttcatgag aaaacgcata atattaagtg tcttgacacc tgctattatg
    11761 cgttttc
//
LOCUS       DBEJJE010000055        11694 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEJJE010000055 DBEJJE010000000
VERSION     DBEJJE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.55"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(919..1122)
                     /locus_tag="ACL3F5_001760"
     CDS             complement(919..1122)
                     /locus_tag="ACL3F5_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HGR0515518.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
     gene            complement(1440..1643)
                     /locus_tag="ACL3F5_001761"
     CDS             complement(1440..1643)
                     /locus_tag="ACL3F5_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HGR0515519.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            1924..4077
                     /gene="blpA"
                     /locus_tag="ACL3F5_001762"
     CDS             1924..4077
                     /gene="blpA"
                     /locus_tag="ACL3F5_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HGR0515520.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            4088..5449
                     /locus_tag="ACL3F5_001763"
     CDS             4088..5449
                     /locus_tag="ACL3F5_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0515521.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5506..5634
                     /gene="blpC"
                     /locus_tag="ACL3F5_001764"
     CDS             5506..5634
                     /gene="blpC"
                     /locus_tag="ACL3F5_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0515522.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(5705..7045)
                     /locus_tag="ACL3F5_001765"
     CDS             complement(5705..7045)
                     /locus_tag="ACL3F5_001765"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0515523.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLAFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(7059..7796)
                     /locus_tag="ACL3F5_001766"
     CDS             complement(7059..7796)
                     /locus_tag="ACL3F5_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0515524.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(7801..8139)
                     /locus_tag="ACL3F5_001767"
     CDS             complement(7801..8139)
                     /locus_tag="ACL3F5_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0515525.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8415..8744
                     /locus_tag="ACL3F5_001768"
     CDS             8415..8744
                     /locus_tag="ACL3F5_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0515526.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8912..9961)
                     /locus_tag="ACL3F5_001769"
     CDS             complement(8912..9961)
                     /locus_tag="ACL3F5_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515527.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9958..10689)
                     /locus_tag="ACL3F5_001770"
     CDS             complement(9958..10689)
                     /locus_tag="ACL3F5_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515528.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10757..11167
                     /locus_tag="ACL3F5_001771"
     CDS             10757..11167
                     /locus_tag="ACL3F5_001771"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0515529.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11177..11464
                     /locus_tag="ACL3F5_001772"
     CDS             11177..11464
                     /locus_tag="ACL3F5_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515530.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
BASE COUNT         3905 a         2433 c         1950 g         3406 t
ORIGIN      
        1 cgtactattc tagtttcaat ctactatact ataccatatt ttgtttcgca gggaatctat
       61 tataaaaggg taagtatttc aaaaacactt acccctttat actttattaa gctctacttt
      121 ttataatact tcaatcccca aatgaaagga agatgttccg ttttttagca agaaaagttt
      181 tcatttcttt gctcctttct ttttagttaa agcaaaatag atcataactg caatcacata
      241 ggctatggta taaaatagct gataccaaat actttcccta agcggataaa gaaagatgga
      301 catgattaga tacaagatga aaatgataag tatttttttc ttcataaaat ttcctcctaa
      361 atgtgtgatt tatcttagtt gaacaagaat ctttacactg ctagtatagc actcattttg
      421 accttggatt actcaaatca tgaatggtca tcaaaacatc ttgaacaata acaagatttt
      481 catctataca aaaatagtta tactcaacaa caatcaaact aaagaaccaa ataaatatag
      541 cttaacatac tttttttgga tttcaaacaa tactgataaa attaataata aatctgtggt
      601 agtacttccc atccctactg ctttccaatt ttataatatt attaattaaa taatatatga
      661 gaaaaaacga acaagactgt gttaataatc tatcttattc gttttattta ttagacttgt
      721 tcagaaatta tttgaagcag tattagctgg ttagaaagtg aatttttaac gttccaacca
      781 gccattagtt tctagttttc gactcttgca ataagctaaa ataatcctga acaacacctg
      841 tatattataa ttgcgaagat tcaacaaaat agcgaacaag tcgattattc attttttata
      901 taagtttaca ataacttttt aacatggaac tggaggtgca ggattccacg aactttttgg
      961 aatgcatact ggaggaacat atggagcagg ttttatcatc cctccgatac tcttcaaaag
     1021 cccccagccg atacatccga tatctccaat aaaacagtca tctccaccac taatcgtctc
     1081 taattctact tcattcaaag taatataatc aattttttcc attgttataa ttcattcctt
     1141 tcgttttact caaggcacaa cacagaatga aaaagtgttg tactctttat tttataatgt
     1201 ttataataat agtgagaaaa cctatcacta ctacaaatca cggggaggtg aataagtgag
     1261 tgatatagcc aatatctcgc atttttatag gtgtcattct ttctatcaag cacaagaact
     1321 gtgactagga gcacgtaaac ttataacaga ataagcgact cgtttgcaaa agaatagttt
     1381 ctatcactgc ataggtcatt aagttatata aattcttata caatacaaca ctactatatc
     1441 tatacacgaa cacagaacca ctgatgagga tttttccggc attgattcgt aaaatcatca
     1501 attgctgtat caacaatgct acctgcaaca tagcctaacc ctgcccaaaa caaagcatcg
     1561 tcaactccaa atattcctcc ctctatccta tcaagcattt cattatccat aacagaaaat
     1621 tgtgacatca tttttgtatt catgacaaat actccttttt tatttttaat ttttgtcttg
     1681 ttgcaacttt gacaagttta gtatatcatt attttttaat ttttttcatc caaatcttga
     1741 attgccatcg aaacgtcttg aattagcttt tttatttcaa gccacctcta aatgtttaaa
     1801 aaaaataatt tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaagattt
     1861 cataaaatat gaacttagtt ttatggcata atatacctat ccactatatg aaaggaattg
     1921 ccaatgactt cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgtggtgtc
     1981 gctgccttag cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga
     2041 gaacttgcaa agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat
     2101 gaaatgggct ttgaaacaag gcctgttcaa gcagataaaa ctctctttga catgagtgat
     2161 gtcccctatc catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt
     2221 gtctatcaaa caaagaaaga ctatctggtt attggtgatc ctgacccttc tgtaaaaatc
     2281 actaaaatgt caaaagaacg ctttttctct gaatggactg gagtagctat ttttctagct
     2341 cccaaaccca gctatcaacc ccataaagat aaaaagaatg gtctactaag cttccttcct
     2401 ctgattttca aacaaaaatc tctcattgct tacattgttc tctcaagctt attggtcact
     2461 attatcaata taggtggttc ttattatctc caaggaatct tagatgaata catcccaaat
     2521 cagatgaaat caactttagg aatcatctca gttggtctgg ttatcaccta tatcctccaa
     2581 caagtcatga gcttctccag agattatctc ctaaccgttc tgagccagag attaagcatt
     2641 gatgtgattt tatcctatat tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca
     2701 cgtcgtacag gagaaatcat ttcacggttc acagatgcta actctattat agatgccttg
     2761 gcttctacca ttctttctct tttcctggat gtttctattc tgattcttgt agggggcgtc
     2821 ttactggcac aaaaccctaa tctcttcctt ctttctctta tttctattcc tatatacatg
     2881 ttcatcatct tttcttttat gaagcctttc gaaaaaatga accatgatgt catgcaaagt
     2941 aattctatgg ttagctctgc cattatcgaa gatatcaacg ggattgaaac tataaagtcg
     3001 ctcacgagtg aagaaaatcg ctatcaaaat atagacagcg aatttgtaga ttatttggaa
     3061 aaatccttta agctcagtaa atattctatt ttacaaacaa gtttaaagca gggaacaaaa
     3121 ttagttctga atatccttat cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt
     3181 tctatcggtc agctgattac ctttaacaca cttttttctt actttacaac tcctatggaa
     3241 aatattatca acctccaaac caaactccaa tctgcgaagg ttgctaataa ccgtttgaac
     3301 gaagtctatc tagtcgaatc tgaatttcaa gttcaagaaa accctgttca ttcacatttt
     3361 ttgatgggcg atattgaatt tgatgacctt tcttataagt atggttttgg acgagatacc
     3421 ttaacagata ttaatctcac gattaaacaa ggagataagg ttagcctagt tggagttagt
     3481 ggttctggta aaacaacttt agccaaaatg attgtcaatt tctttgaacc ctacaaagga
     3541 catatttcca tcaatcatca ggatattaaa aacattgata aaaaagtctt gcgccgtcat
     3601 attaattacc taccacaaca agcctatatc tttaatggct ctatcttgga aaacttaact
     3661 ttgggcggta atcatatgat tagccaagaa gatattctaa gagcttgtga attagctgaa
     3721 attcgtcaag acattgaaag aatgcctatg ggctatcaaa ctcagctctc tgatggagct
     3781 ggtctatcag gaggacaaaa gcaacgaata gccctcgctc gtgctctttt aactaaatct
     3841 cctgttttaa tactagacga agctactagc ggtcttgatg tcttgactga gaaaaaggtt
     3901 atagataatc ttatgtctct aactgataaa accattctct ttgtagccca tcgtctcagt
     3961 atagccgaac gaaccaaccg tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt
     4021 agtcaccaag agttaatgca ggcgcaaggt ttctaccatc atctattcaa taaataagga
     4081 gaatgtcatg aatcctaatc tttttagaag cgtcgagttt tatcagagac gttaccataa
     4141 ctatgcgaca gtgttaatta tacctctttc attactattt actttcatct tgattttctc
     4201 ccttgttgcc acaaaagaaa ttactgttac ttcccaagga gaaatcgccc ctacaagtgt
     4261 cattgcctcc attcagtcaa ccagtgataa tcctatccta gctaatcatt tagtggcaaa
     4321 tcaagtagtt gaaaaagggg acttactcat caaatactct gaaacaatgg aagaaagtca
     4381 gaaaactgcc ttagcaactc aattacaaag acttgagaag caaaaagaag gacttggaat
     4441 tttgaaacaa agcttagaaa aagcgactga tcttttttct ggcgaggatg aatttggcta
     4501 ccataatacc tttatgaatt ttactaaaca atcccatgat attgaactgg gtatcacaaa
     4561 gactaacacc gaagtttcaa atcaagctaa tctttccaat agcagttcat cagctattga
     4621 acaagaaatt acaaaagttc aacaacaaat tggagaatat caagagttga gagatgctat
     4681 cataaataac agagcacgct taccaactgg caatccgcac cagtcaattt tgaatcgtta
     4741 tcttgtagcc tcacaaggac aaacacaagg aactgcagag gagccatttt tatctcaaat
     4801 taatcaaagt attgcaggtc ttgaatcatc tatcgcaagc ctcaaaattc agcaagctgg
     4861 tatcggaagt gtagcaactt atgataacag tttagcaacc aaaattgaag tactccgcac
     4921 tcagttttta cagacagcct cacagcaaca actaactgtg gagaatcaat taacagaatt
     4981 aaaagtacaa ctagatcaag ccacacagcg tttggaaaac aataccttaa cctccccaag
     5041 taaaggtatc gttcatctga acagcgaatt tgaaggtaaa aatagaattc caactggtac
     5101 agaaattgct caaatattcc ctgtcatcac agatacaaga gaagtactaa tcacttacta
     5161 cgtatcttct gactatctac ctctactaga taaaggacaa actgtaagat taaaactgga
     5221 gaagattgga aatcacggca ccaccatcat cggccaactt cagacaattg atcaaactcc
     5281 taccagaaca gagcaaggaa atctctttaa attaaccgct cttgcaaaac tatctaacga
     5341 ggatagtaaa ctcatccaat atggcttaca aggtcgcgtc actagtgtaa ctacaaagaa
     5401 aacatatttt gattatttca aagataaaat tttaacacat tctgattaat tttcagataa
     5461 cactctataa ctatttatta tcttatcaaa aaggagaatc ataacatgga taagaaacaa
     5521 aacctaactt catttcaaga actaacaact accgaactca accaaattac aggtggagga
     5581 ttgtgggaag atttattata taacattaat agatatgctc attacatcac ataagaactt
     5641 catcatccaa tacaactata aaaaaataag accgagaaac aagtactctc ggtcttattt
     5701 ttcatcattc tgtatgtatc acagtaagta cctgacgaaa gacttgattt tgacaggtgg
     5761 tatttagact ggtattagga tggctttcca caatcttcat gacggtatag agaccaactc
     5821 ctctctcctc ccctttagaa ctggctccaa aggagaagat ttcagaaata tcgatgccct
     5881 cttctttgat ggagttttcg atgataaagg tctcctgtgc tccatttttt aaaaaggcga
     5941 ttgaaacatg aggttgacta gcttccacac tggcttcaat agcattgtca caaaggatag
     6001 acacaatggt tagaaaatca agtagactca tcccctcgac ctgaatctcc tcaggaactt
     6061 cgacattaaa gacaatgttc ttatctctgg cttttaaaaa tttccctgct agaagacttt
     6121 tgagggcttt atcacgaata tttaccaatc tgcccaggtc atatttattg ttctgcaatt
     6181 tctgactgga atcctttaag acggagccat agacctcttt tatctgctcc atatcctcct
     6241 cttcaatgcc cagacgtaag ctagtcaaga ggttggtata atcatggcga aaactccgta
     6301 cttccttgta aagctcctct atatgccgac tatagcgttc catatctcta tagcgcaggg
     6361 cctgctcttg ttccaatctc tcatagagtt tttccttcaa ataggtatcc aatttcttga
     6421 taacccccat aaaaaagagt aggtaaaaga ctaggatgag atggcgaaca gtctttgatt
     6481 gaatactttg ttcatattca aaaaaagaca gactttccat gactagatag tagccaccca
     6541 ttatccagtt aatctgagtc agggactttt gaaaggcttt atcgagaatc tcctttctca
     6601 agctagtaaa atcgtagtcc aaccatttca aaaaagctag agaaatgaag aaattgaaaa
     6661 ttattataca taacccagta aatgagtagc catcatatac ttgcccttgt cccaaaaatg
     6721 gaagcacaaa ataggagact cctctataaa agagattcac caatatcatt ggaaagagac
     6781 cataaaagaa aaggagtttt ttaggaagcc ctctcaataa taagaaagat aagcctatgc
     6841 cgtacaaggg ttccataaaa taagataggt aaacatttcc tactatatag ctaatcatca
     6901 caaaaacaaa ggccaacagt atcttaaaaa gaaaggcctt aaaaatcctc tcgaaagcaa
     6961 gatcaattcc atccacctta aagaagatga caatttctag tccattagta acaagtgtat
     7021 acaacaatat ccaagcaatg ttcataaatt ctcctagctc agtgtaattt attgatggcc
     7081 tcagacactt ccctgacctt ataacgggcg attagacaac ttccaccatt gggaaagaaa
     7141 agcagttttt ctttcttatc caaatgcacc acatttgcag gattgatgag aaaagagcgg
     7201 tggcactgca agagacgggg ctcctgcttg aaaacctcct ctaaactcgc tgtaaattcc
     7261 agcctgtctg tcttggtata gagaataaca cgatgggctc tgggcgacgt ttcgagatag
     7321 taaacctctt taaaaggata ctgaaattgg gcaaattttg atttaaagta aaagcaatct
     7381 tccgccagac ttttactatc ttgactattg gcatagagga gggctgtctc gatccgagat
     7441 tcaaactcct ctgctgacaa ggccttatca atgtagtcca aagcagacac ttggtagcga
     7501 aaagacaggg gcataaactc cgagtgagtc gtcacaaaga caatcagggc ataaggatcc
     7561 cgatcccgaa tctttctagc cacttccagt cccttcatct cttcatttcg aatctcaata
     7621 tccaaaaaga atagctgatg ggcccccttc tcatgcactt cagccagcag ttggtccggc
     7681 ttgccaaata cctcaaaaga gctaggaatg atatgatgtg ctttcaaaag tttctcaatc
     7741 gtcgtttcaa ttctagtctg ttgggaaaaa tcatcctcta aaacaaatat tctcatcttc
     7801 ttactctccc tctttcaacc atttttgacg aatttctcta tagcgacgtc tggcatactt
     7861 gacagcgtat tgaccttctt ctccgagaaa aaggattctt tcttgaaaat caatcgattt
     7921 taatttatca agattaacca aacaatttcg atgacatctc atcaaggttt ccccacattg
     7981 gttctcaaga ttacttaaat tttgaagcat attaaaacta gcttcttctg taacaatctg
     8041 tacggtatgg gctttagttg gatgtgtttg gatatagtag atatcgtcga tgtttacttt
     8101 atagactgtt ttctgcgtct gaataatcat atatttcatt ggattctcct cctaagaaaa
     8161 gaataacaga aaaggtctag cccaagcaca cccaatccta aacagtcttt gaaaactcct
     8221 aaaaggatta ttttctacaa catcatgatg agcttacaac tattttatca taaaattcac
     8281 tcagcgcaat tcaagacatt tcaatgacaa ttaaagattt gaataaaaaa aaagaattaa
     8341 aagtgataaa ctaacagtat caaaacacag ttgccagaag taagactggc acccagatta
     8401 aaggaggcat tcccatgaca gatacagacc ccatcaaaag agctcatact ttgattactg
     8461 acttaaacaa agcctaccaa gcatgcaaac aggcaagcgc tgacgacgtc cgctttcagg
     8521 agcaattaaa ctctattctt ggttttctag ccaagactga aacagtggat aatcgattct
     8581 tgattgaact agaaaaattt taccagactt ccagtcttct catgggactc agcgctcttg
     8641 atccagatgc tccaactcgc gccgcttggc gggcctatga ccgcttccac tttgaccaag
     8701 tcaagaccaa gttaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc
     8761 tgtacttgag tacggtaaga cgacgctgac gtggtttgaa gatattttcg aagagtataa
     8821 gtctctacgg accaaccatt atcctgtagt aacaaaaaag aagctgagac agactgaact
     8881 caacttcttt tttagtgtcg tatcagcaat gttagtcctg catctgacgt tttacctgat
     8941 aaggcaaata caagactagt aaaaccaaac cagctcctag taaggctaga agggctagtt
     9001 tttcttggaa ggtaatcaac ccaacaacta attccacaag taaaacaaaa ctggtcaatc
     9061 ctcgaactac ctcctgtaag cctttttcct tttgcccctt gtccagcgga aagagttggg
     9121 tcaaatactg gtagtcaaag gcatgataga gggccagcaa ctggaagagc aagaggtagt
     9181 taaagagaac taccactgct gtcgcaatcc aagcttgctc gataaaaacc tgcgccagta
     9241 cggaaagtaa gagaagacga agactgagag caaagaggtc gccatttcgc agataagaac
     9301 gcagatagag attttgccaa atcttcccag gcaccttctg aacagccttt aaaataaagt
     9361 ccagataggc acgacgctta acgctgtttg aaattccctt gacctgcgta aagagggcaa
     9421 agaaacgaag caagacttgc ttacgcttgc tttcttgaga aataagatag tcccagtcca
     9481 gtccagtttc agtgaaaaat ttgctggcct tttgacaaaa gtggaaatat tttcctaccc
     9541 ccaataaaag cacatagagc agaaaaactg gcaagccata acccattgct aaaaataaag
     9601 gcgcaaataa cagcaagaaa agggtctgta caaagagcca aaagactagg gaaatgccag
     9661 tttgacgctt gagatggagc ttgatttcct cttctccgac taagagaaag agcttgtctg
     9721 gagcctccat ataggtggca attcctcccc aaagtaaaag taaaacagac gtaattccta
     9781 caaacaaaag gataggccaa tgattttcag gaaaatgttg taagagttga ctgtactggt
     9841 aggctagaaa gcccaacagg acaagcagga acaagacaaa gtggtcattg agcacatagc
     9901 gcagataacc aagacactcc ttacgaaagg cctgctttct ctttaaaaac aagtctttca
     9961 taggtcctcc tcttttgtca gagccaagta aatatcattc aaactagcct caggcatatc
    10021 aaaggcttcg cgtagttgca ggagattgcc tttggcacgc acctctccct tgtgaagaat
    10081 gacaaaggca tcacacatct tctccgccga atccagcacg tgggtactca tgagaataga
    10141 cttgcccttt tgcttctcca cttccaaaag ctgaatcaaa tcagaaatag ctagcggatc
    10201 aagaccaagg aaaggctcat ccacgatgaa aagacttgga tccaccacaa aagcacagat
    10261 aatcatgacc ttctgcttca tcccttttga aaaatgaaca gggaaccagt ctaatttctg
    10321 gtccagacgg aacatcttta acaagggctc tactcgttcg aaagccactt tttgctcaat
    10381 accgtaagcc atagcaaccg tttcgatatg ctctctgagg gtcaattcct catacagact
    10441 aggcgtctca ggaatgtagc caatctgctt gcggtagcta gtcgcatctc cttgcagagt
    10501 caggccattg atattgatgg agccactata aggtgccaac agaccgataa tctcattgat
    10561 cgtcgttgat ttcccagcac cattgagacc aatcaaaccg accaactgcc cactttcaac
    10621 agtaaaggac acatctttca aaacaggaac atgaacatag ccacctgtca ggtttttaat
    10681 ttctaacata ttttctccaa atctggtata atgtagctat attatatcaa aattcagtac
    10741 agtagaggta gattttatgt cagattgcat tttttgtaaa atcatcgcag gggaaattcc
    10801 tgcttcaaaa gtatatgaag atgagcaggt ccttgccttt cttgatatct ctcaagtaac
    10861 actaggacac accttggtcg tgccaaaaga acactatcgc aatcttttgg agatggatgc
    10921 tacgagcgcc agccaactct ttgcccaagt accaaaagta gctcaaaaag tcatgaaagt
    10981 cactaaggct gctggtatga atatcatttc caactgtgaa gaagtcgctg gtcaaacagt
    11041 ttttcatact cacgttcacc ttgtgcctcg ctacagtgct gacgatgacc tcaagattga
    11101 ttttatcgcc cacgaaccag actttgacaa acttgctcaa gtcgctgaaa ccatcaaaaa
    11161 cgcttaagga gttgctatga aattatccaa cctactgcta tttgcaggag ctgcagccgg
    11221 aagttatctg gttacaaaaa atcgccaaac catcacagat gaagtcttga ataccactga
    11281 ccgcgttcaa gctatcaagg acgatgtgga tattatccaa aacagcctgc aaatcattaa
    11341 ccagcaaaaa gaacttatca aggaatacca agaagacttg acttacaagt ttaaggtctt
    11401 ggaaaaggat atccagacta gactagctgt gataaaagaa atgcagggaa ctgaagataa
    11461 gtaaaaagag ccccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta
    11521 gaatagcaca ccatagtttc taaagcattg ttagagatta ctttaaaatc ctcttatcaa
    11581 tttgttcata ttctatttca atctattata tatatcccat caactatgca tcataattta
    11641 ggtaactcat actcaataaa aatcaaaaag caaactagaa agctaggcac agac
//
LOCUS       DBEJJE010000056        11592 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEJJE010000056 DBEJJE010000000
VERSION     DBEJJE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.56"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            470..1180
                     /gene="deoD"
                     /locus_tag="ACL3F5_001773"
     CDS             470..1180
                     /gene="deoD"
                     /locus_tag="ACL3F5_001773"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0515531.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1203..1727)
                     /locus_tag="ACL3F5_001774"
     CDS             complement(1203..1727)
                     /locus_tag="ACL3F5_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR0515532.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSISKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1780..2016)
                     /gene="rpsT"
                     /locus_tag="ACL3F5_001775"
     CDS             complement(1780..2016)
                     /gene="rpsT"
                     /locus_tag="ACL3F5_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0515533.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2084..3004)
                     /gene="coaA"
                     /locus_tag="ACL3F5_001776"
     CDS             complement(2084..3004)
                     /gene="coaA"
                     /locus_tag="ACL3F5_001776"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0515534.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3194..3598
                     /locus_tag="ACL3F5_001777"
     CDS             3194..3598
                     /locus_tag="ACL3F5_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515535.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWTKWIAAGSYCFLVLRIATEGYFFHMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            3805..4395
                     /locus_tag="ACL3F5_001778"
     CDS             3805..4395
                     /locus_tag="ACL3F5_001778"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0515536.1"
                     /translation="MSKMYYAEHPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4392..5669
                     /locus_tag="ACL3F5_001779"
     CDS             4392..5669
                     /locus_tag="ACL3F5_001779"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0515537.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVSKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5687..6349
                     /gene="deoC"
                     /locus_tag="ACL3F5_001780"
     CDS             5687..6349
                     /gene="deoC"
                     /locus_tag="ACL3F5_001780"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0515538.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6336..6725
                     /locus_tag="ACL3F5_001781"
     CDS             6336..6725
                     /locus_tag="ACL3F5_001781"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0515539.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6815..7867
                     /locus_tag="ACL3F5_001782"
     CDS             6815..7867
                     /locus_tag="ACL3F5_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0515540.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            8011..9546
                     /locus_tag="ACL3F5_001783"
     CDS             8011..9546
                     /locus_tag="ACL3F5_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515541.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9539..10597
                     /locus_tag="ACL3F5_001784"
     CDS             9539..10597
                     /locus_tag="ACL3F5_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515542.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGSVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10600..11556
                     /locus_tag="ACL3F5_001785"
     CDS             10600..11556
                     /locus_tag="ACL3F5_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515543.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3298 a         2070 c         2654 g         3570 t
ORIGIN      
        1 aagtcagtca catatataat ccaaggcgac gttgacgtgg tttgaagaga ttttagaaga
       61 gtataaacag aaaggtagag cgcgtgttct aatttgaaca cgagtagaaa acttttctaa
      121 aaacaaaaac gaaaggatgg gtaaactgta ttcgctgaac tgaatacggg cgactctcct
      181 ctaaatcaaa attaagaaag gaattgaccc caccctaaaa gtagtgggaa aaagatagtt
      241 ggtctagcga gcatcgctca ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt
      301 ttggtatctt tctcaatata aaatataaaa taaagaaagg tagagcgcgt gttctaattt
      361 gaacacgagc ggaaaactcg gaaaatagat aatctgactg aaaaatcagg atttctcgtc
      421 aggttcctaa ttttcagtcg ttttcttctc gctctttgta tcataaatta tgtctatcca
      481 tattgctgct cagcagggtg aaattgctga taaaattctt cttcctgggg atcctcttcg
      541 tgctaagttt attgcggaga atttccttgg tgatgctgtt tgttttaacg aagtgcgtaa
      601 catgtttggt tacactggta cttacaaggg tcaccgtgta tctgtcatgg gaactgggat
      661 gggaatgcca tctatttcga tttatgcgcg tgagttaatc gtagactacg gtgtgaagaa
      721 attgattcgt gtgggaactg caggttcttt gaatgaagag gttcatgttc gtgaattagt
      781 tttggcgcag gcggctgcaa ccaactcaaa catcgttcgt aatgactggc cacagtacga
      841 ttttccacaa attgctagct ttgatttgct tgataaagcc taccatatcg ccaaagaact
      901 tggtatgact actcacgttg ggaacgtttt gtcatctgat gtcttttact caaattactt
      961 tgaaaagaat atcgagcttg gtaaatgggg agtcaaggct gtggaaatgg aagcagcagc
     1021 tctttactat cttgctgccc aataccatgt tgatgcgcta gctatcatga ccatctctga
     1081 tagcttggtc aatccagacg aagacacaac tgcagaagaa cgtcaaaata ccttcactga
     1141 tatgatgaag gttggtttgg aaaccttgat tgcagaataa ttatagccaa aaaggaagcc
     1201 ctttatgaat tgtaggactt ccttttctta tccagaaatt gatctagctc tctctgattt
     1261 cgaagaatag tgactttatg tgaatattct tggcaaagtt tttggtaatt ttctttttga
     1321 gttttgctac gtccatccca aagaatccat ctgataaact cccagtcaaa gcgttcaggg
     1381 caatctgccg ccatactttc tctgactttt ccacggtatt taagataacg cttaaaggct
     1441 ctaaagagac aggtcaatgg cgaaaaattg agaaagatga tttggtcagc ttcttgcatt
     1501 cgttcttggt agtagcacca agaataatta ccatcgatga cccaagcttt atgcttggtg
     1561 agaaagtttt ttatctcggt taacatccat tcgtggtcac tgtcttgcca accaggttga
     1621 aattggagtg tgtccatgtg cagttttgaa atggagtagt agttagataa cttttctgct
     1681 agagttgact taccagaacc agaatatccg ataattgcga ttttcatttt ctaccttttc
     1741 ctatttggag acaaaaaaac agcctctatg gactgtttct tatttagcaa gtttagctga
     1801 aagacgagct ttatcgcggc ttgctttgtt tttgtgaatc aaacctttag tttctgcttt
     1861 atcgatagct gagctagcag cacggaaaag ttcttcagat gggtttgctt cgaaagcttt
     1921 tatagcagta cgcatagctg atttttgagc tgagttcttt tcgttttgtt taacgttcaa
     1981 ttcagcgcgt ttgatagctg atttaatgtt tgccaatgtt cttacctcca tatttactaa
     2041 ctataccatt atatatgaaa acttacgttt tgacaaggga aaattatttt tttaagtaaa
     2101 tttcatcgat ttcatggttc ttgcttttat gaagaatcac ttctgcacga tttctggttg
     2161 gttcaatata attttgtaga tttgtgagat tgatactggt ccagacctga tgggcaaagg
     2221 cttccacttc cccaatcggc atctgagtaa aacgataata gtagctatca gggtcgtttt
     2281 gggctagact cagcattttc aagaaacggt ccagatacca actttcaata tcatccactc
     2341 cagcatctac atagatggaa aagtcaaaga agtcagtgat atagagacga tcgttttgtg
     2401 gattttgaaa gacattgatt ccctcaacaa ttacaaaatc agcagctttg acactttgtt
     2461 tctcttcggg tacgatgtcg taaacttcat gagaatagac aggaatatct acatcttgtc
     2521 catttttgat gcggtccaag aagttgagaa gagcttccat atcatagctt tcaggaaatc
     2581 ctttacgatt taaaatcccc tgctcaatca aggtttgatt gggatagaga aaaccatcag
     2641 ttgtaaccaa ctcaaccgta gcatctgtaa acgtacggga cagtaggatt tgaagtaggc
     2701 gactggttgt ggattttcca acggcaacac tcccagaaac cccaataata aaaggttgag
     2761 atttactttc acgttggagg aaaattcctt ttgaaaaggc taaatcttcc ttagttcgct
     2821 tgtaaatctg aatcagatga gccaagggga gatagatatc tgtaacgtct tggagactga
     2881 tttggtcatt aaaactcttg atagattcca attcttcttc tgtcaaagga ggtgttgtct
     2941 ttcgatgtaa agattgccaa gtctggcggc tgattttttc aaaatgtaaa aattcgttgg
     3001 tcatttgttt tcccctagat attttgtcta tcataccata aaaagctaaa aaaataaagc
     3061 ggtttcttga atgtggtaag tcaatggtat atagtataag tgatcaattt attgatgaaa
     3121 taggagatag attctactga tttataagct tataaagggg gctttttggt tcacaactta
     3181 taggaggtgt actatgaaaa tcttaaaacg ttacatattg gaactctgtt ttattttaag
     3241 ttttgcttta ccttttataa aaggagccaa tgcagataat ggtagatgct ttgtggaaac
     3301 ctattacggt tttacttttt tgatggaaca tgctattgta acagctgtct ttatctgttc
     3361 gtttttaatt gctttcttac taaaaaaacg atggacgaaa tggattgctg cgggtagtta
     3421 ttgcttttta gtcctacgga ttgcgacaga gggttatttc ttccacatgt cactagaaga
     3481 tttgatacga ctttggacaa gtttggaaat cctgacacaa acgtatcagt tgggctttta
     3541 tctaaacatt ttgttaggaa ttttgttgat aataaagtat tttaaggtta agcaatagaa
     3601 ataataatct gcctgattat agatgataaa ctttttgttt ttatctggac tgtgatattt
     3661 atagttctaa atggtttatt atttataagt gttgaaagag attgaagaaa atggcttcgt
     3721 gacttgcttt cttcggtctt tttcgtttta ttatcaattt gtaaacgatt tacaatttga
     3781 gtcaaattat ggtaaaatag tgtcatgagt aaaatgtact atgcagaaca tcctgacgct
     3841 gctcacgaca ttcatgagtt gagagtggac ttgttgggag aaaaaatgac ttttttgaca
     3901 gatgcgggtg tttttagcaa gaaaatggtt gactttggaa gtcaactctt gctcaagtgt
     3961 ctggatgtca accaaggaga gacagtccta gatgtaggct gtggctatgg tccattaggt
     4021 ttgtccttgg tcaaggttta cggagttcag gcgaccatgg ttgatattaa cactcgtgcc
     4081 ctggatttag ctcagagaaa tgctgaaaaa aataatgcaa aagcgacgat atttcaatct
     4141 aatatttatg caagagttca agggcgattt gaccatgtca tttccaatcc tcctatccgt
     4201 gcgggcaagc aagtcgttca tgaaatcatc gagaaaagta aagatttctt ggaaattggt
     4261 ggagatttga ccatcgtcat ccagaaaaaa caaggagctc caagtgccaa gtctaagatg
     4321 gaagatgtgt ttggcaattg tgaaatcctt aaaaaagaca agggatacta tatccttaga
     4381 agtgtgaaag aatgagagca gttgatttaa tccaaaaaaa acgagacggt caagaactga
     4441 cttcaagtga aattgaatgg ctgatagaag gctatgtatc aggaactgtt cctgattatc
     4501 agatgtctgc ctttgctatg gctgtttatt ttaaaggaat gacgactcga gaaatctctg
     4561 atttaacgat gaatatggtt aagactgggc aagagtttga cctgtcagcc attgatggtg
     4621 tgaaagttga caagcattct actggtggtg tcggcgataa ggtaaccttg attttagctc
     4681 ctcttgttgc tagcttcggt gtgcctgtag caaaaatgag tggtcgtggt cttggccata
     4741 caggcggaac aattgataaa ttggagtcca ttaagggcta tcaagtagaa cgtagtcaag
     4801 aggattttat tcgtcaggtt caggatattg gagtatctgt cattgggcaa tcagaccagc
     4861 tggtcaaagc agataagctt ctctatgctc ttcgtgatgt gaccgcaact gtcgacacga
     4921 ttcctttgat tgcgagttcg gtgatgagca agaaaattgc ggcaggggcg gatgctattt
     4981 tgctagacgt gactgtcggt gagggtgcct tcatgaagac ggttgatgag gcgcgtgagt
     5041 tggctcaaac tatggtagat cttggtaagg ttgttggacg gaagacagta gcagtgatta
     5101 cggatatgag ccagcctttg ggacgagcga ttggaaatcg tctggaaatc cttgaagcat
     5161 tggagatttt gcaaggtcaa ggacgtcagg atattaccca ctttatttgt gaattggctc
     5221 aaattatgct tggtttggca aatgttaaca aaactgttga agaagttcgc caacatcttg
     5281 aaaatggtca agcactggct aagtttgagg aaatggtgca agcccaaggt ggagacttgg
     5341 aagacctcta tcgtcctgta aatgtagctc atgtggtgga aatccctgct caggaaacgg
     5401 gtgtcatttc agctcttcca gctatggact ttggtcttta tgccatgagg ctgggtgctg
     5461 gtcgtgcagt taagtctgat gtcttggact atgaaacagg aattgttttt gaaaagaaga
     5521 ttggagactc cgttcaaaag ggtgaaattg tttcaaaagt atacacaaat gaaaaaattc
     5581 cacctcaact agttacagat ttccaaaaat gtgttaaaat aagtgatgaa gtgaaaaaaa
     5641 tccgtgaaat tgtagaaatc atctcctaaa tggagggaaa accgaaatga aattaaataa
     5701 atatatagat catacgcttt taaaacaaga tgcaaagaaa aaacaaattg atagtttgtt
     5761 gtctgaggct agagagtatg actttgccag tgtttgcgtt aatccgacct gggttgaaca
     5821 tgctaaaaaa ggacttgaag gcacagatgt taaggtttgc acagtagtag gtttcccttt
     5881 gggagcaaca acttcagccg tgaaagcatt tgagacaaaa gaagctatcc aaaatggtgc
     5941 agatgagatt gatatggtga tcaatgttgg agctctcaaa tcaggtaatt tagccttggt
     6001 tgagtcagat attcgcgcag tagtggaagc aagtggtgat aagttagtga aagtcattat
     6061 tgaagcttgc cttctgacag accaagaaaa aattgttgtt tgccaattgg cccaaaaagc
     6121 tggggctgac tttgttaaaa catctactgg cttttcaact ggtggtgcta cgatagcaga
     6181 tgttagatta atgcgtgaaa cagttggatc tgatatggga gtcaaggctg ctggtggagc
     6241 tcgttcttat gcagatgctc ttgcctttgt cgaagcaggt gcgacccgta tcggaacgtc
     6301 agctggggta gctattttaa aaggagaatt ggcagatggc gactactgag ttgattgaac
     6361 tggcaattga aaccagcaaa catgcctatg tcccctattc tcactttcct atcggagcag
     6421 ttttagtagc caaagacgga agtgtttaca cgggagtgaa tatcgaaaat gctagctatc
     6481 ctttgaccaa ttgcggtgag agaacagctg tttttaaggc tatatctgaa ggccaaagag
     6541 aattttcaga attgattgtc tatggtcaaa ctgaaaaacc gatctcgcca tgtggtgctt
     6601 gtcgccaagt aatggtcgaa ttttttgaac aagatttaaa agtgacctta gtcgcaaaag
     6661 ataaatcgac ggtcgagatg acggtcgggg aattacttcc atactctttt acagacttaa
     6721 actagtctga gtcgctctct gagtggcacg gtccttgtgg ccaaccaatc catacttgca
     6781 acatcgttgc acatcttatt taggaggttc agtaatgaac aagaaacaat ggctaggcct
     6841 tggtctagtt gcagtggcag cagttggact tgctgcatgt ggtaaccgct cttctcgtaa
     6901 cgcagcttca tcttctgatg tgaagacaaa agcagcaatc gtcactgata ctggtggtgt
     6961 tgatgacaaa tcattcaacc aatcagcttg ggaaggtttg caggcttggg gtaaagaaca
     7021 caatctttca aaagataacg gtttcactta cttccaatca acaagtgaag ctgactacgc
     7081 taacaacttg caacaagcgg ctggaagtta caacctaatc tttggtgttg gttttgccct
     7141 tcataatgca gttgaagaag cagctaaaga acacactgac ttgaactatg tcttgattga
     7201 tgatgtgatt aaagaccaaa agaatgttgc gagcgtaact ttcgctgata atgagtcagg
     7261 ttaccttgca ggtgtggctg cagcaaaaac aactaagaca aaacaagttg gttttgtagg
     7321 tggtatcgaa tctgaagtta tctctcgttt tgaagcagga ttcaaggctg gtgttgcgtc
     7381 agtagaccca tctatcaaag tccaagttga ctacgctggt tcatttggtg atgcagctaa
     7441 aggtaaaaca attgcagccg cacaatacgc agccggtgca gatattgttt accaagtagc
     7501 tggtggtaca ggtgcaggtg tctttgcaga ggcaaaatct ctcaacgaaa gccgtcctga
     7561 aaatgaaaaa gtttgggtta tcggtgttga tcgtgaccaa gaagcagaag gtaaatacac
     7621 ttctaaagat ggcaaagaat caaactttgt tcttgtatct actttgaaac aagttggtac
     7681 aactgtaaaa gatatttcta acaaggcaga aaaaggagaa ttccctggcg gtcaagtgat
     7741 cgtttactca ttgaaggata aaggggttga cttggcagta acaaaccttt cagaagaagg
     7801 taaaaaagct gtcgaagatg caaaagctaa aatccttgat ggaagcgtaa aagttcctga
     7861 aaaataatgg atggaagtca tttcttagga agcggccaag ggccgctttt ttaagagttg
     7921 agacaaagtc attttgtctc agtaaagctt gctactagac aaactagcaa gttttattga
     7981 aataaaataa gactctgaaa ggaagagcac atggcacacg aaaatgtcat tgagatgcgt
     8041 gatattacca aggtgtttgg tggatttgtt gctaacgaca aaatcaactt gcacctacga
     8101 aaaggtgaaa ttcatgcact tttaggagaa aatggggctg gtaagtccac gctaatgaac
     8161 atgttagcag gccttcttga accaactagt ggtgaaatcg cggtcaacgg tcaagttgtc
     8221 aatctcgact ccccatctaa agcagctagc ttgggaatcg ggatggttca ccagcacttt
     8281 atgttggttg aagccttcac agtggctgaa aacatcattt taggtagtga attgactaaa
     8341 aatggtgtgc tagatatcgc tggagctagc aaagaaatca aggctctttc tgaacgttat
     8401 ggcttagctg ttgacccttc tgccaaggta gcagatatct cagttggagc ccaacaacgt
     8461 gtagaaattt taaaaacact ttataggggg gctgatatcc ttatctttga cgaaccaacg
     8521 gctgttttga ctccatcaga aattgatgag ttgatggcta ttatgaaaaa tcttgtcaaa
     8581 gaaggaaaat caattatctt gattacccac aaattggatg aaattcgcgc agtttctgac
     8641 cgtgttacag ttatccgtcg tgggaaatca attgaaaccg ttgaaattgc aggggctacc
     8701 aatgctgatt tggcggaaat gatggtagga cgttctgttt cctttaaaac agagaagcaa
     8761 gcctctaaac caaaagaagt ggttttgtct atcaaagatt tggtggtcaa tgaaaaccgt
     8821 ggtgttccag ctgttaaaaa tctgtccttg gatgttcgtg ctggagagat tgttggtatt
     8881 gcggggattg atggaaatgg tcagtctgaa ctgattcaag ccattacagg tcttcgtaag
     8941 gttgaatctg gtagcattga gctaaaagga gattcaattg taggcttgca cccacgtcag
     9001 attacagaac taagtgttgg gcacgttcca gaagaccgtc accgtgatgg cttgattttg
     9061 gaaatgatga tatctgaaaa tattgccctt caaacctact ataaagaacc acatagtaaa
     9121 aatggaattt tgaattattc aaatattact tcttatgcta aaaagctgat ggaagagttt
     9181 gatgttcgcg ctgccagtga attagttcct gcagctgcac tctcaggagg aaatcaacaa
     9241 aaagcaatta ttgctcgtga aattgatcga gatcctgatc tccttatcgt tagccagcca
     9301 actcgtgggt tggatgtcgg tgccattgag tatatccaca aacgcttgat tgaagagcgt
     9361 gataatggca aggctgtcct tgttgtcagc tttgaattgg atgagatttt aaacgtctca
     9421 gaccgtattg ccgttatcca cgatggtaag attcaaggta ttgtatcacc agaaacaacc
     9481 aataaacaag gacttggtgt cttgatggct ggtggaaact tgggaaagga gaagagtgat
     9541 gtctaaaaaa ttacaacaaa tttcggttcc cttgatttct gtattcctag gaattttact
     9601 cggagccatt gtcatgtgga tcttcggtta tgatgctatt tggggctacg aagaattgtt
     9661 ctatacagcc tttggcagtc tgcgtgggat tggagaaatc ttccgtgcta tgggtcctct
     9721 ggtcttgatt ggtcttggtt ttgcggttgc cagtcgagct ggtttcttta acgtcggact
     9781 tcctggtcag gctttggcag gttggattct cagtggttgg tttgccctgt cgcatccaga
     9841 tatgccccgt cccttgatga ttctagcaac catcgtgatt gccttgattg ctggtgggat
     9901 tgtcggagcg attccaggta ttcttagggc ctatctaggg acgtcagagg ttattgtaac
     9961 catcatgatg aactacattg tcttgtatgt agggaatgcc tttatccatg ctttccctaa
    10021 agacttcatg caaagtacag attcgaccat tcgtgttggg gctaatgcaa cctatcagac
    10081 accttggttg gctgagttga ctggtaactc acggatgaat attggtattt tctttgccat
    10141 cattgccgtt gcagttattt ggttcatgct caagaaaaca actcttggtt ttgaaatccg
    10201 tgcagttggt cttaatccac atgcttcaga atatgctggt atttctgcca agcggactat
    10261 tatcctatct atgattattt caggtgcctt ggcaggtctt ggtggatctg ttgaaggttt
    10321 gggaaccttc cagaacgtct atgttcaagg ttcgtcatta gctatcggat ttaacggaat
    10381 ggcggttagt ttgcttgcgg ccaactcacc aattggtata ctctttgcag ccttcctatt
    10441 tggcgttctc caagttgggg ctcctggtat gaatgcggcg caggtaccat ctgagcttgt
    10501 cagcattgta acagcgtcta ttatcttctt tgtcagtgtt cattacctta tcgaacgctt
    10561 tgtcaaaccg aaaaaacaag ttaaaggagg taagtaaaga tgtctattat aaccttgctc
    10621 cccctcttgg tgtcttctat gctgatttac tcagcacctc tcatctttac aagtatcggt
    10681 ggtgttttct ctgaacgtgg tggtgtggta aacgttggcc ttgaaggaat tatggttatg
    10741 ggtgcctttt ctggagttgt ctttaacctt gaatttgcag aacaatttgg agcagcaact
    10801 ccatggctat ccttgcttgt agcaggattg gttggtagtg ttttctctat catccacgca
    10861 gcagcgacgg ttcatttccg tgcagaccat gttgtcagcg gtacggtatt gaacttgatg
    10921 gcgcctgcct tggctgtttt cttagttaaa gttctttata acaaaggaca aaccgacaac
    10981 ctaagtcaaa cttttggacg ctttgatttc ccagtcttgg caaatatccc agtgattggt
    11041 gatatcttct tcaagtcaac tagtctactt ggttatctgg cgattgcctt ctcattcctt
    11101 gcttggttta ttctctttaa gactcaattt ggtcttcgtc tccgctctgt cggtgaacat
    11161 cctcaagcag cggatacctt gggaatcaac gtctacaaga tgagatattt agggattatt
    11221 atttcaggtt ttctaggtgg aattggcgga gcgatttatg cgcaatcaat ctcagttaac
    11281 ttctcagtga caactattgt tggacctgga tttatcgccc ttgctgcgat gatctttggg
    11341 aaatggaatc caatcggtgc tatgctttct agtctcttct ttggactttc acaaagtttg
    11401 gctgttatcg gttctcaatt gccgttccta caaggagtgc cagcggttta tcttcaaatt
    11461 gcaccttatg ttttgacaat tcttgtctta gcagccttct ttggaaaagc agtcgcacca
    11521 aaagcagatg gtatcaacta catcaaatca aaataagcat acaaaaaaac gtcagtccaa
    11581 tgactgaact gc
//
LOCUS       DBEJJE010000057        11068 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEJJE010000057 DBEJJE010000000
VERSION     DBEJJE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.57"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            97..1275
                     /locus_tag="ACL3F5_001786"
     CDS             97..1275
                     /locus_tag="ACL3F5_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0515544.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1503..1949)
                     /locus_tag="ACL3F5_001787"
     CDS             complement(1503..1949)
                     /locus_tag="ACL3F5_001787"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515545.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFITPQKQEQGLGSKALRKFVSLAFE
                     NEDIDSISLNVFEANQIAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            2019..2678
                     /locus_tag="ACL3F5_001788"
     CDS             2019..2678
                     /locus_tag="ACL3F5_001788"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0515546.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLGLLFLLYSWGWLSLGQVVLITAG
                     LTLGIYDFHHQKYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2650..3426)
                     /gene="trpA"
                     /locus_tag="ACL3F5_001789"
     CDS             complement(2650..3426)
                     /gene="trpA"
                     /locus_tag="ACL3F5_001789"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0515547.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQVLVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(3419..4642)
                     /gene="trpB"
                     /locus_tag="ACL3F5_001790"
     CDS             complement(3419..4642)
                     /gene="trpB"
                     /locus_tag="ACL3F5_001790"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0515548.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(4620..5219)
                     /locus_tag="ACL3F5_001791"
     CDS             complement(4620..5219)
                     /locus_tag="ACL3F5_001791"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0515549.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(5206..5973)
                     /gene="trpC"
                     /locus_tag="ACL3F5_001792"
     CDS             complement(5206..5973)
                     /gene="trpC"
                     /locus_tag="ACL3F5_001792"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0515550.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(5970..6974)
                     /gene="trpD"
                     /locus_tag="ACL3F5_001793"
     CDS             complement(5970..6974)
                     /gene="trpD"
                     /locus_tag="ACL3F5_001793"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0515551.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(6985..7551)
                     /locus_tag="ACL3F5_001794"
     CDS             complement(6985..7551)
                     /locus_tag="ACL3F5_001794"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0515552.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(7548..8909)
                     /gene="trpE"
                     /locus_tag="ACL3F5_001795"
     CDS             complement(7548..8909)
                     /gene="trpE"
                     /locus_tag="ACL3F5_001795"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0515553.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(10050..11051)
                     /locus_tag="ACL3F5_001796"
     CDS             complement(10050..11051)
                     /locus_tag="ACL3F5_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0515554.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         3127 a         2564 c         2011 g         3366 t
ORIGIN      
        1 taagtaatga aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag
       61 gattttaaga atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta
      121 caactaagag ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa
      181 atcgctacta aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt
      241 aaagaaaata ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa
      301 aaaatcctgc tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa
      361 aaacatttca cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa
      421 attgttacta aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag
      481 caattcttaa ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt
      541 cgctatttag ataattataa aataacaaca aacaatcctt tatggcaaca tatcgactta
      601 gaaatgattc aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg
      661 gctataggta aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat
      721 tttgctagag gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat
      781 ctaatgattg gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc
      841 gggcgcaagg gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa
      901 attctatatc atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat
      961 attgatatcc aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt
     1021 atccatcaag ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac
     1081 tctcaaaaaa tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta
     1141 tatagtgaaa tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt
     1201 gaaccttaca atgattttac agccgcacac tcagctattg cactttgttt gtatcataca
     1261 attctacatt cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc
     1321 ataaaaagcg aacaaacctg ttttctgaaa atcagaattc tgttttgttc actttcttta
     1381 tatttggaat tatactccta tctccccttt ttcataatgt atagtaaaat gaaataataa
     1441 caggacgaat cgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
     1501 tactattcta gtttcaatct actatatttt cgtacaggtg cttcaaccat ttgaacgatt
     1561 tcaaatcctt ctttttggta aagattctga gctatttgat ttgcctcgaa gacatttaga
     1621 gaaatactat ctatatcttc attttcaaag gccaaactaa caaatttcct taaagccttg
     1681 ctacctaagc cttgctcctg tttctggggg gtgataaaaa atctcccgat atgaagattg
     1741 ctgtcttcta gcctgatttt ctggataaat cccacaaact cttgttcatc aaagattgaa
     1801 aagactcctt ccaaggcttg aagggtcagt agaaaaggaa tccttggtcc catccattgt
     1861 tcttgaaagg atttgcctag ggagttggac cactggcata caaattgagc gttttctgtg
     1921 ctcacctttt cttcaaaacg aattgtcatc ttttcctcac caccttatct atgtttctcc
     1981 attatactat ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc
     2041 tcgtcgggag cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat
     2101 ccattatcag ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cctttagatt
     2161 tgattccgat tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct
     2221 atcctgtctg gtatgccctc tttgaattaa gcttaggact cctctttctg ctttactctt
     2281 ggggatggct ctccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatct
     2341 acgactttca ccatcagaaa tatcccttac tggtctggat gactttccag ctaatcctaa
     2401 tagcttcctc tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc
     2461 attttatcga tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg
     2521 tctttagcgt aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg
     2581 cctttctcct gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta
     2641 cttgtttgat tatttttggt aagctactgc ttgtctgata aagtcctgaa tcggctctcc
     2701 ttggtggaga gcttttacta ttttcgaacc gacgataaca ccatctgaca ccgcattgaa
     2761 gcgttccaga tcggcttgac tagatacacc aaaacctgtc aagactggga tgtcggccac
     2821 ttgatgaagt tgcgccaagt gcttgtccaa atctgcacgg taattgcctg atttccctgt
     2881 cactccattg atggcaacgg catagacgaa tccctccgcc ccttcaatca actctttctg
     2941 gcgctcaatt cctgtggtca agcttactaa aggaatcaag gcgatatctg tatctgccaa
     3001 aaatggttct acaaagttgg catgttcatg aggcaggtct gggataatca agcctttcac
     3061 agctgtatca gccagatctt tgacaaagtt ctccacaccg tactgaaaga gggggttgaa
     3121 gtaggtcatg atgaccagtg gaatctctgt ttcaatggtt ttcaaggttt caactaaaac
     3181 ctgggtagag gtcccgtggg ctaaactgcg caagccagct tcttcgataa caggtccatc
     3241 tgcaacaggg tctgaaaagg gaatacccac ttcaattgca gagacaccca aatcttctag
     3301 aaagtggatt gtttctccta gtccatccaa acctttctcg tggtcaccag ccatgatata
     3361 gggaacaaaa attccttttc cagttgcttt tatagcattc aatttttctg ttagtgtctt
     3421 aggcatgagc ttctcccttc tttgctgcat ctgcttccaa gcggtctttg acttgaacca
     3481 catccttgtc cccacgacct gataggcaga caatcataga cttttctggt ccaagttctt
     3541 tggccaattt caccgcaaag gcgatagcat ggctagattc caaagctggg ataatccctt
     3601 ccacacgaga caagagttgg aatccttcca aggcttcttc gtctgtcaca gggacatagc
     3661 tggcacgttt aatatcgtgg tagtgagaat gctctggacc gataccagga tagtccaaac
     3721 ctgctgagat agagaaggct tcaagaattt gaccatgggc atcttggagc acatccatga
     3781 gggaaccgtg aaggacacct ggacgaccct tggtcaaggt agctgcgtgg tgctccgtat
     3841 ccacaccaag ccctgctgct tcagctccat acatagctac tgactcatct tctacaaagg
     3901 gatggaagag cccgatagca ttcgacccac caccaacaca ggctactagg gcatctggca
     3961 gatctcgacc tgtcaagtca cggtactgtt gtttagcttc tcgaccaata acactttgga
     4021 agtcacgaac gatttctggg aatggatgag gacccaaggc agaaccaagg atatagtggg
     4081 tatcatcgat attagccacc catgaacgaa gggctgcatt gaccgcatcc ttgagcacgc
     4141 gcgaaccatc tgtcacggcc tcgaccttgg ctcccaaaag ctccatacgg aagacattga
     4201 gggcttggcg tttgacatct tcctcaccca tgtagatggt acattccatg ttaaagaggg
     4261 ctgcagcagt tgcagttgcc acaccgtgct gaccagcacc cgtttctgcg ataattttct
     4321 ttttacccat gcgtttggca agccaaactt gtcctaaggc attgttaatc ttgtgggctc
     4381 ctgtatggtt aaggtcttcc cgtttgagat aaatcttggc tccgccaata tgctgggtca
     4441 agttttttgc gtagtaaagg ggagtttcac gtcccacata ctggcgcaaa agttggttta
     4501 attcctcttg gaaacttggg tctgcctgac tttcacggta ggccttctcc aactccaaaa
     4561 ctgctgtcat caatgtttct gggacaaaac gtccgccaaa ttttccgtaa aatccatctt
     4621 tatttggttc ttgatatgcc attctttacc ctctctataa atcttctaat cttttcatga
     4681 tctttttgtc catctgtctc cactccgctt gatacatcta ctgcataggg agtaaaatgt
     4741 tgaattgctt ttactacatt gtcttcatta aggccacctg cgataaagaa agactgaggt
     4801 aatccagtcg tatccagttg accccaatca aagggctggc cacttcctgc cacaggggca
     4861 tcaaagagta gataatctgc ctgagaattg gggacatgcc catttccatc tacctgcaca
     4921 gcctgaatac tagcacaagg caaattctca aataaatcat ctgctacctg accgtgaact
     4981 tgaaccaagt ccaagccaac tttgtcaatc gcttccagca gttctacccg acttggtgaa
     5041 acaaatactc caaccttttt cacatctgca ggaataagct ttgccaactc agctgcctct
     5101 tctaaagtca cctgtctttt actaggtgca aagacaaaac cgatatagtc ggctcctgct
     5161 gaaacggctg tttccaccgc ttctttggtc gatagtccac aaattttaac ctttgtcaat
     5221 ctgcaactcc ttgattctct gggccacatt ttctgcctgc ataagagctg tccctaccaa
     5281 aattccgtta aagtatgggg ctagtcgttc cgcatcctgc cctgtgaaaa tggcagattc
     5341 agaaatgtaa tagcgacctt cctcaaagta aggggctaaa tctacactgg tctgcaagtc
     5401 gacctcaaag gtagtcaagt tgcggttgtt gaccccgata atctcagcac caagtctgtg
     5461 ggctacctct agttcagcta gattgtgagt ctccactaag acttccagac caagctctgt
     5521 cgcgtagtca tacagttcct tgaggcgttc ttcggacaag gctgccacaa taagcaagat
     5581 aactgtcgca cctgcattgc gagcgcggat gatttgcttt tcatctatga taaagtcttt
     5641 gttgagcgtc ggaatctcta cctgactgga aatttcccgt agataatcca aatgcccttt
     5701 aaagaaaacc tcatctgtca acaccgaaat catcactgct ccgttttctt cataagtctg
     5761 ggcctgttgc acaatatcca catcgagatt gatatctccc aaactagggc tagctttctt
     5821 gacctcagcg attacctgca agcggtcctg atgattcttc aaaaattctg ccaagcgata
     5881 ggtctggcgc agaggctgga tttgctccag cttcatctgc tccacctcac gcgccttctg
     5941 ctctaagatt cgtgctaaaa attcctgact catttttggt actcctgtaa cagtctgagt
     6001 ttttcaagag ccttgcctct agcaatcact tgacgggcca aggcaactcc ttccttgatg
     6061 ctatcaatct taccattagc atagaaacca agaccagcat tcaagactgt cgtttccaag
     6121 aatggacttg cttcgttttt cagaacgcta agcaaaattt ctgcattttc ctgagcattc
     6181 ccaccacgaa tatcttccat agcatagcct tccattccca aatcctctgg agtaaagctt
     6241 gacaagctga tttcgccatt ttcaagaagt gcaatcttgg ttgttccgtt caagccagct
     6301 tcatccaacc cttctggtcc agcaaccacg atggcacgtt tgcgacccat atttttcaaa
     6361 acctgagctg tactttctag gagttctgga cgactaattc caagaagctg tgtttctaaa
     6421 gccattggat gaatcagtgg accagtcaag ttcataatcg ttggaattcc caattccaaa
     6481 cgagctggca tgatgtattt catagctggg tgcatatttt tagcgaagag aaagacgatt
     6541 ccagttttat caaagacctt acctagttca gctggtttga ggtcaagatt gattcccaag
     6601 gcttcgagga catctgcgga accagattta gaagaaatcg agcggttacc atgcttggcc
     6661 atgtgaatac cgccaccagc caagacaaag gctgcagttg tggaaatatt aaaactgaaa
     6721 gacttgtccc cacctgtacc acagttgtcc atggcatcat gaatctcagt tggaatatgc
     6781 tgggcatgtc ctctcatgac ttgggcaatg gctgtgcgtt cttcaggtgt ttcccccttc
     6841 atcttaagag ctaagaggag agaagcaatc tgcgcttcag ttacacgccc agttacgata
     6901 cgctcaatga catccgtcat ttccacacct gataaatttt caaattttgc tagtttttca
     6961 ataatctctt tcatcctagt ttcctcactt tacaaccttc tcgataaaat tccgaataga
     7021 agacaagccg tctggcgttc caatgctctc tggatggtac tggaagccat aaatcggtag
     7081 gtttttatgt tgaatcccca tgatggcttg gtcatcagtc gaacgagctg tcacttcaaa
     7141 gtcttctggc atttcctcaa tcaaaatact gtgataacgc atgaccgcac gtccatcctc
     7201 aataccttga tacaaaacag atggcgcttc aaagttgata ttgctctgtt tcccatgcat
     7261 gacttttgga gccaaaccta gcttaccacc aaagacttct gcaatggctt ggtgacccaa
     7321 acaaatccct agaatcggct tcttgcctgc aaaatcacga atcatgtctt ccatctttcc
     7381 agcatcaact ggccaaccag gaccaggaga aaagaccaga ccatctgctt tttcagcttc
     7441 ttcatacagc ttggaatcat catttctcag aacctgaact tctgcaaaat tcccaatgta
     7501 ttgggccaag ttataggtaa aagaatcata gttgtcaatc aataaaatca tggtcttagt
     7561 tctccaattc tagtcataga ttttgctttg ttaatggttt cttggtattc gttttgggcg
     7621 atagagtcgt agacaatccc tgccccagcc tgcacatagg ctctttgatt tttgagaatc
     7681 atggttcgga tggcaatggc caaatccata tcacccgtcg cagacaagta gccgattgct
     7741 cctgcatata cgccccgttt ttccgtttcc agttcataga tgcgtctcat cgctcgaatt
     7801 tttggtgctc cagaaacggt tccagcagga agcgttgctt tcaaggcatc catggcagtg
     7861 agttctgcaa gcaaacgtcc cttgaccaca ctggtcaaat gcatgacgta gcggaagagc
     7921 tccacctcca tatacttagt aacttggaca ctggccgttt cagagatgcg gccaatatcg
     7981 ttacgcccca agtctaccaa cattcgatgt tctgctgttt ccttctcatc agagaggagg
     8041 tcagtcgcca aggtcttgtc ttcttcatcc gtagcccctc ttggtcgcgt ccctgcaatc
     8101 ggattggttg tcacgatgcc atttttgaca gaaaccaaac tttctggact agctccgatg
     8161 atttgataat ccccaaaatc atagaaataa aggtaattag aaggattagt cacgcggaga
     8221 tttctgtaga agtcaaatgg atttccagta acttctgctg agaaacgctg gctgagtaca
     8281 cattggaaca tatctccgtt acgaatcaag tcacgagctg tttctaccat tccctcaaac
     8341 ttatgtggag cgatatgcgg tttgaagtct aacggagata gatccaaatc ttcaaattca
     8401 tttggagcag gaatgcgtaa ttcctcaagc acttggttca aggatttttc caaggcctct
     8461 tgactgcgct cactatagag agcatcctct atgacatgta tcttctcctt cttgtggtca
     8521 aagaccatat agctctcata gacaaagaaa tgcatgtctg gcgtcccaat tgtatcctca
     8581 gggatttgac caatttcttc ataaagcgaa atcatatcgt aacccacaaa accaatggct
     8641 ccaccaccaa aaggtagctc tgagtggtgc tgactcttat gaatcacttc ataaaggaaa
     8701 tccaagggat ctcgatcaat cacttgacca ttttgataaa gaactccatt ttcaaactta
     8761 atctcaaaaa ctggattata ggctaggata gaaaaacgag ctgtttcctt gtctctcgga
     8821 atactctcta agataacctt atgttgcccc tttaagcgca tataagccaa gattggtgat
     8881 aagacatctc catgaatgat tcgttccatt gtaatttccc tttcagttct acttctagtc
     8941 agtggtgact gtatgaaaaa tccccacgca aaataacttg cgtgaggacg aaattcgcgg
     9001 tgccacctca attataggat ttctcctatc tctcattcct gtctcagata tctcctgtaa
     9061 caggctgtgc gataaagggc actcccttga gaatgatgtt ttcttctctc gtttcagatg
     9121 aacccaactt tacagctttc tctgcttgtt ttcagcaacc acaagctctc tgtgagagaa
     9181 aagactgtaa tttttccatc tattattttt tagcttctag taatctgcaa tcgcagctag
     9241 gtccttgcct ccacgaccag agacattgat gaagagatgt tcatctcggt acacctttat
     9301 actcttcgaa aatctcttca aaccgcgtca acgtcgcctt atcgtaggta tggttactga
     9361 cttcgtcagt tctatctgca acctcaaaac agtgttttga gcagcctgcg gctagtttcc
     9421 tagtttgctc tttgattttc attgagtatt actagctttt ttcgtattag tccagccttt
     9481 ttgtttactt ttagtaggag gcaaggagct gtagatagaa ctcaagttca tcaaagcgag
     9541 ttaaggccct aataaaagat aaagcaaacg acggatagaa aaaagcccac acacagaata
     9601 tacttccgtg tgagggcgtt ggtaacgcgg tgccacctca attataaagg gactatccct
     9661 ttacatctct gccttgttta acaacaagct gcactgtaag gtgtgcgcac cgaattttca
     9721 ttgtttcaaa ttcattttca aaatcagccc actttcacta cttccaacca cctattcaca
     9781 atcaccacag gctccctgaa gatcaaaaat agttactttt ctgatttgtt gaacttattt
     9841 taatactttg ttttttcttt gtcaagactt ttttacgatt tttttgaaaa tatcattcga
     9901 atatgaccat gtcttcctta gatcgaacat gaacatgtcc cacttgttag aaattggatc
     9961 caactcaata gaaactgaat ggaggctaaa cagaacttat tttagaacac tccatatttt
    10021 ccactaggat tttcaagaat taaacaatac tagaaactct gtctcctaac aaatttagga
    10081 gaaacttcaa cagatgtgac actttcccct ttaataattg ctaaaacacc ttctatcatt
    10141 tctttagcca atttaacata attgggagca attgtagaca aagctggagt ataatactga
    10201 gaaataggaa tattatcaaa tccaatgata gaaatatcat ctggaataag aattcctttc
    10261 tcatagcacg cacgaatcaa gccctgaacc ttttcatctc ctgaaacaaa aataatgtcc
    10321 ggataatttt gggtagtcaa gtgctgcatt gcataagaat aaactgaatc aattgtagat
    10381 aagccataaa tgacttttaa atccataaag taatttttat cattcagaaa agaacgcaca
    10441 cctctttcac gatccttatt aacatgggat tctcccccca taagcaacca catattttta
    10501 aatttttctt cagttacagc tttcatcata tcataagtag cttgaaaatt attattagat
    10561 acatagacta ctccagacgt ttgagattca ccgaaaacaa gaaaaggcat atggttcttc
    10621 tttaaatact gaattctgat atcatctaca ctttcataaa aaacaataac accatctact
    10681 aggctacctg tgcttgatat aattgaatta ctaattgtat cctcctctcc aaagtactca
    10741 actatagcat taacaccaaa ttctttacac gtccgtaaca ctttatctaa cagcgtatga
    10801 aaccaaatta aaggaaaaga gtcgattttt tttacagaaa tcaatatatt tatagcttct
    10861 tttttagtta aattttttgc atacgcattt ggaatatacg acaattcctc tataactttt
    10921 tgaatcgctt gataagtttc ttctttaaca tttactccac cattaataac tcgtgaaact
    10981 gtttttggag aaaaacctga taaacgtgca atatcataaa tagttacctt tttcccattt
    11041 atatttttca tttcagtcct ccattacg
//
LOCUS       DBEJJE010000058        10948 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEJJE010000058 DBEJJE010000000
VERSION     DBEJJE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10948
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.58"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            155..319
                     /locus_tag="ACL3F5_001797"
     CDS             155..319
                     /locus_tag="ACL3F5_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0515555.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            403..969
                     /gene="amaP"
                     /locus_tag="ACL3F5_001798"
     CDS             403..969
                     /gene="amaP"
                     /locus_tag="ACL3F5_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0515556.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            981..1151
                     /locus_tag="ACL3F5_001799"
     CDS             981..1151
                     /locus_tag="ACL3F5_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0515557.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1190..1798
                     /locus_tag="ACL3F5_001800"
     CDS             1190..1798
                     /locus_tag="ACL3F5_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0515558.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1829..2032
                     /locus_tag="ACL3F5_001801"
     CDS             1829..2032
                     /locus_tag="ACL3F5_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0515559.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2142..2381)
                     /locus_tag="ACL3F5_001802"
     CDS             complement(2142..2381)
                     /locus_tag="ACL3F5_001802"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515560.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            2659..2904
                     /locus_tag="ACL3F5_001803"
     CDS             2659..2904
                     /locus_tag="ACL3F5_001803"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0515561.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3182..3952)
                     /locus_tag="ACL3F5_001804"
     CDS             complement(3182..3952)
                     /locus_tag="ACL3F5_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0515562.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3967..4815)
                     /locus_tag="ACL3F5_001805"
     CDS             complement(3967..4815)
                     /locus_tag="ACL3F5_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR0515563.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4812..6287)
                     /locus_tag="ACL3F5_001806"
     CDS             complement(4812..6287)
                     /locus_tag="ACL3F5_001806"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR0515564.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6610..7965)
                     /locus_tag="ACL3F5_001807"
     CDS             complement(6610..7965)
                     /locus_tag="ACL3F5_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0515565.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDKILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7975..8292)
                     /locus_tag="ACL3F5_001808"
     CDS             complement(7975..8292)
                     /locus_tag="ACL3F5_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0515566.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANQRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYKRF
                     EKN"
     gene            complement(8309..8626)
                     /locus_tag="ACL3F5_001809"
     CDS             complement(8309..8626)
                     /locus_tag="ACL3F5_001809"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515567.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8642..9538)
                     /locus_tag="ACL3F5_001810"
     CDS             complement(8642..9538)
                     /locus_tag="ACL3F5_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0515568.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9541..10803)
                     /locus_tag="ACL3F5_001811"
     CDS             complement(9541..10803)
                     /locus_tag="ACL3F5_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0515569.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3768 a         2194 c         1690 g         3296 t
ORIGIN      
        1 gacttttcta tattaaagtt atataatagt aataatcaaa gaaattgatt ttttgatatt
       61 aaaataaaaa aggagggtag gcagtgttgt gatcaattat tgctggaggt cttattggtc
      121 tcttggcagg taaaatcact aaaaaagtag ttctatggga atcatcgcaa atgtattcgc
      181 tggtttagtc ggggcatatg caggacaatc tcttttaggt agttggggtc catcaatcgc
      241 tggaatggct ttgctcccat ctattgtagg tgcagcgatt gtgattactg tagtgtcatt
      301 ctttacaggt agaaagtaaa cttttcgcca gtaaagttag caaactattt ttaaatcaat
      361 gacgggaaaa atagtttaaa tgttaaatcg aaaggattgt atatgtcaaa agcaaagaaa
      421 atatgtttca ttattttctg tattttaatc ttgacaattt tccttcctgt tttgatagat
      481 tatcatcaag ttagtgatct aggtattcat ctacttagct ggagacagaa ctccgtagtt
      541 gaattctatc ttgctagata tgtcttttgg gggacagtgg ttctatcaac tttagtttta
      601 ttatccattt tagttgtgat gttttatcct aaacgttact tggaaatcca acttgaaact
      661 aaaaacgata cattaaaatt aaagaattcg gcaatcgaag gttttgttag aagtttggtg
      721 agtgatcata gattgatcaa gaacccaact gttcatgtaa atttacgaaa aaataaatgt
      781 ttcgttcatg tagaaggtaa aattcttcct tcagacaaca tcgctgacag atgccaaata
      841 attcaaaatg aaataactaa tggattgaag cagttttttg gtattgagcg tcaagtaaaa
      901 cttgaagttg cagtaaaaaa ttaccaacca aaacctcaaa acaaaaagac tgttagtcgt
      961 gtgaagtaag gaagtaaaaa atggaatggc ttaaacaata tcgatatcca attatcgctg
     1021 gtctcatagg cgtatttctg gcttgtttga ttgtctcctt tggcttcttc aaaacaatat
     1081 ttgtattgat tttaggagca ctgggagttg cagctggatt atatatcgaa aaaaactata
     1141 tagataaata aaaaaataaa aattactaat ttaattaaag gagtttcata tgtcaaacga
     1201 aaaaaacaca aacactaacg tagaaaagaa agatgctact gttgtagctc acgaaatcaa
     1261 aggggaactt acttacgaag ataaagttat ccaaaaaatc attggtcttt cactagaaaa
     1321 cgtttcaggt cttttgggaa tcgatggtgg tttcttctca aatcttaaag aaaaaatcgt
     1381 taacagcgat gacgtaacaa gtggtgttaa cgtagaagtt ggtaaaacac aagttgcagt
     1441 tgacttaaac gttattgttg agtaccaaaa aaatgttcca gctttatatt cagaaatcag
     1501 agaaatcgta tcttcagaag ttgctaaaat gactgacttg gaaattgttg aaatcaacgt
     1561 aaacgttgtc gacatcaaaa ctaaagaaca gcatgaagca gactcagtaa gccttcaaga
     1621 tcgcgtatct gacgttgctg aatcaacagg agaattcact tcagaacaat tcgaaaaagc
     1681 taaatctggt cttggatctg gtttctcaac tgttcaagaa aaagttagcg aaggtgtaga
     1741 agctgttaaa ggtgcagcaa atggtgtagt atctcacgaa aacactcgtg taaactaaga
     1801 taaaataaat ataacaggag aaattatcat gtcagtagaa gaaaaattaa atcaagctaa
     1861 aggttctatt aaagaaggtg ttgggaaagc catcggtgat gaaaaaatgg aaaaagaagg
     1921 agcagctgaa aaagttgttt ctaaagtaaa agaagttgcc gaagacgcta aagacgctgt
     1981 agaaggtgct gtagaaggtg ttaaaaacat gttgagtggc gacgataaat aaggttaaaa
     2041 gttactttat ctttttggta acattagtca aaagagtctg agtcaagatg attctcagaa
     2101 aacaaaaagc tagagattcc caattgcgga actctagctt tttaattttg cctctttctc
     2161 ttattatatt tcagcaggtt gttggccatg agtatgaatc ccatgtcaat tctcacttga
     2221 cgcttacctc tcagatgaca tctcttataa cccaaacaaa cctttatctg cccaaagaca
     2281 gatttcatat caatcttacg tttagcgaaa atttgtctac ccttggaaga taaaagtgcc
     2341 tgatattctt tagtttttaa acactggtaa cgttcattca tatacagtcc cttttgaggg
     2401 gctgattcag gttcataatc gcagtcaaca ttgatttcaa ggctgtttgc tttctatctc
     2461 ccctttttca tgatatattt tcgtacggtg cttcaatagt ttctatagta aaatgaaccc
     2521 aaaatagtac acgttgcggt ataatgttct tgtggcatat tcattagatt ttcgtaaaaa
     2581 gttctctcct atttgtgagc gaacaggtat agtcaattga ttgtcagttt gaagaccaag
     2641 agtcgtaagg caaaggatat ggcagaatcc atccaagggt ggctggcaca atttctagtg
     2701 aacctcttta aatctattac gtttgactgt ggaaaagagt tttcaaaatg gaaagatatt
     2761 tccaatcatc acgatagtga gagctttttt gcgaatctag gatgtccaag acagcggtgt
     2821 ctcaacgaac attcaaatag acttttaagg tgtcatgact tgccaaagca gacagatttc
     2881 aacgaagtca gtcaagaatt ttaggctggg taaaaactca atttcaggag aaaatgaaat
     2941 aaatattccc acaataaaat gcatagtatc aaagtttttc caacacctga tattatgcat
     3001 tttttaattt taaagacttt ttcccagcct caagaaatca catcccacct aaatcctttg
     3061 gataccaaat acctcatcag gtattttctg agttggtaag actgtctagc ttaatttgac
     3121 aaatggaggg cgttaaatcc agtttttaca ggaagtctat ttaaatattt tcacactgac
     3181 cttacaaaat atgaaataaa ttatataaag tcattcccat gacaaagaat aacatccctt
     3241 taaaacagta tcttacccaa ttttcaggta agacttttga tacaaccgtc cccaataccc
     3301 ctccgcatat agaagcaaga aaaataactg gaacaggtgc taaatgatac tgatttaaac
     3361 ctgtaaccac aacaattgta gccaaatgag acagctggga aaagaaaata attgcaagag
     3421 aatacatcgt tgcttctttt atcgaaatag aaaaaaacac catcaataaa gatacattga
     3481 gcggaccacc accaatccct aaaaaactag aaattaagcc caatagaaga ccacaaatca
     3541 tatagaatcc tatcttatca aattgataag tttttttaaa atctgttaaa acaaatgata
     3601 caagtagcat cacaaatagt aaaatcattt gaacaatgga tactagccgt actgataatt
     3661 gagataacaa aacttgaaaa ataagatgac ctagaaatcc tcctaaaaca gaagaaaagg
     3721 ataccgtaaa aatcaatctc cattttatct ctttactttg tgaaaatctt ttgattgttg
     3781 aaataatcgc cattataaaa acagagaaac tagaataaaa agcaatatca ctgaccgaat
     3841 ggtacccaaa actatccata agtggcttaa ttataattcc accacccatg cctgatatag
     3901 aacccaatcc actagctatt ataatgatta gaaaataaat aatctcaacc actttttaag
     3961 tccatcctat tctttcaaac atctaaaacc tagatggcta ctagtggaag tagaaataca
     4021 tccatttcta gcagctactc ggtatcgatt acaataagaa caatgacata aaaaggaacc
     4081 tcctctgata gcatactcct catcttgtat cccatatttt ggtaactcat agtcatcttc
     4141 attaaaacta gctaataagg tatatctcgg attgcgacac cattcccaaa cattcccaat
     4201 catttgatat agaccaaaat cattaggtaa aaattcatag acaggagccg ttcctataaa
     4261 tccatctaag gcagtatttt cataaggaaa tcttccttgc caagtattgg catgataata
     4321 tccaccttct aaaagagtat ctccccaagg atattcagat tgtcttcctc ctctagcagc
     4381 atattcccac tgtgcttcag tcggtaaaga cattccgctc caattacaga aagccaatgc
     4441 atcttctaaa gcaacatgaa ctactggatg gtcttctaaa cccactagat tactgttctc
     4501 accgtaggga tgtttccagc aagcgttcga aacttgtaac caccacggag ccccagcagg
     4561 atgaggatat ccctcccttt ctgcctccgg aacgaacaat ataaaaacaa aagaccactc
     4621 ttgtcgctca gctagtgttt tatagcctgt ttctttcaca aattgagcaa attcttgatt
     4681 cgtaactgga gtatccgcaa tggaaaaatc ctttacacta acagcgactt gaggaccttc
     4741 aaaatcatct aaaaagccct cttcagaatt tgttcccatc ataaatgtcc cacccttgat
     4801 ttttttcatt ttcatgattg actatccccc gttttcgtta gagttggcgt tattttagaa
     4861 agttcaacag gaactaactc ttcatccaca acaaaacctt cttctctata tctaagaaag
     4921 tctactaatt ttttcttcat ctgacgaaca ataggttgat atttttcact tggatacaaa
     4981 tcattcattt catgcggatc ttttttcata tcaaataact gataatgatt taaaacagga
     5041 aaccagataa atttccactg gtctgtcaaa atatattgac tagaatcttt tcctaaagca
     5101 tgttcaccat gaaattctgt tcgccacccc tcgtactgtc caaataataa attcttaaca
     5161 ctccgtccat ctagttcatc tgtagtagtt cctcctgcca aatccacgag tgaaggaaaa
     5221 atatcttgaa ttttcactaa ttgcttgatt gttcccctat taccagctat caatccagcc
     5281 ggatcgtaaa taaacgaagg aatgtggata cttccctgat aaggatatcc ctttctaaac
     5341 agataatgtt caccaagctg atctccatga tccgaaacaa accagataat cgtatcttta
     5401 tcatgacgaa attcttttag ggcagtcaaa aagcgactaa tttgatggtc tatatgagta
     5461 atcaatccaa aataagcagc aaccattctt ctttgatcat cttcctttaa tttccctctt
     5521 aaagcataaa tagacggaat ttgcttttct aatacttccc aattcccgat atgcaaatcg
     5581 agaaattgag gcaagcgttc catatacata tcaaaatagt attttggggg atttaatgga
     5641 gcatgtggtt tttcaaaaga cattttgaga aaaaaaggaa ccgttggatc tcttctttgt
     5701 aaaaatgaaa tggactcact cacaacccag tttgttggat gtaacttctc atctttatcc
     5761 caaggtctag cttcccaaga attacaatcc attccgtcat caatcaaatc aacatcataa
     5821 ccaactttac cctttaaaaa ggctagatag tcactagcat aatcaaattg acttccataa
     5881 gccttatcat actttctatc aacatgtaga tacccatcgt gaagtaagac atgatcaaac
     5941 ccaagtctct gtctggaagg aaaaacatgc atcttaccaa tacactctgt ttgataaccc
     6001 atatctttaa agacttttgg aagagtatta gtaaaattcc aaggcacctc atcttgataa
     6061 ccaacacgtc cacttttatc ttggtctaag ccagtcaata aagctgccct agcaggaacg
     6121 caagaaggaa ctggagaata ggcattttca aaattataac ctacactagc catcatatct
     6181 aatgttggag tgctaactag cttatcctta ctattcaagg ataagacgtc tgctctcatt
     6241 tgatctacaa caatcaaaat aatatttggc tgttttgtct gaaccataaa atctcctttc
     6301 taatatggca aaagaggcac aagaagatat ctacctttac tgcacccctt tctatatcaa
     6361 tctctctata taaaacaata acattcttgt tatgttttat agaaaaatga actaaaatat
     6421 gactaaatcg attaggaaat tcaaatcatt ttctagtact gttttagaag ttacagtgta
     6481 ctattccaac ttcaataaac tataaacctt tgtctaataa caattttagt ggagataaga
     6541 aatcctacac ctaactcatc ttacacgtaa tctatttcta ttttatcaca aaaaacgcaa
     6601 gtaagaccat taactcaatt cagttttatc tgccattttc acaaatggga aataagtcaa
     6661 gacactaata atcaaacaaa caactgataa gatgatggca cgccaatcaa atgctgtaga
     6721 gaagaaacca tataaaattg gaggcattac ccaagtaaca ttttgtgtaa caggtgaaac
     6781 aagaccccag cttgttgccc agtaagctac cgttgccatg aaaaccgggc taagtacaaa
     6841 tggtataaat agcaaaggat tcaagacaac tggtaaacca taattgaccg gctcaccaat
     6901 attaaacaga actggtgcta gaccaagttt agcaactttt cgataatgac tgtttcttga
     6961 aaaaattaaa atagcaagta ctaatcctaa tcctccaaac cagacaaacg ccccaaaaga
     7021 cccacttgtc catatataag gaatcggttc acctttttgg aaagcatcca gattcgctaa
     7081 catagcaact ccaaatagcc cttccatgat gggagccaat acatttcctc catggagacc
     7141 aaaaaaccag aataacttat tcaaaaagat catcagaata actgcaaaga aactttgaga
     7201 caaacctagt aatggcgttt gtaacacctt gtaaacccaa tcaatcaata agtcattgct
     7261 aagtaaatgg aaaacataag tcaagatggc tactatatac atcgccataa atcctggaat
     7321 gatagaagtg aacggcttag caatcgcagg gggaactgaa tctggtaact tgattaccca
     7381 gttctttttc attactttac agaaaataat agaggctaaa aatccaatca tcatggctgt
     7441 aaagtagcct ctggcattga tatggtttcc tggaatcaca ttcccaatag ttaccatcag
     7501 atttttacca tcaaatgcta gattatcaat tccttgtaag attttatcta atttcacatc
     7561 tcctacattt gccaaaggga aactctttgt aactgtactt ccaatcgaaa tgacaaacga
     7621 ggcaagtgat accaaaccag cagaaactgt atcaaccttg taaatcttag caatattcac
     7681 tcccaagcaa tagatgaaca acaaggaaac aattggtata cttcccttga ataccaaatt
     7741 attgatgtca acaagccact gaaaggtttt cgtaatactt tctaggtgaa attgttgtgg
     7801 taaatccact agaaaagcat ttaataacaa agcaatggaa cctgtcataa taacaggcat
     7861 agtccccaca aatgaatcac gtaaagcaac taaaaacttc tgatttccaa ctttcattgc
     7921 aattggagaa agtttttctt gcattttatc caacattgta ttcataccaa actcctaatt
     7981 tttttcaaat cgtttgtaca cttctaccac ttcttttgct aagtcaacaa aggtcagact
     8041 cgtcattaaa tgatcttgcg cgtgtaccat caagaggcta attgaagttt cttccccctg
     8101 tgcctctctt gtcaacattt ctgtttgagc cttatgcgcc tgtaataagg cagcattcgc
     8161 atcagctaat ctttgattgg cttttgagaa atcacctttt tttgctgcct gaatagcctc
     8221 catagcatta cttttggctt ccccaccata cataattagc cccattacag attctaaatt
     8281 actttcattc atagcattct cctcaatctt agtctaataa actttcagct aaatctaaga
     8341 ctttagaacc attcatcatt ccgtaatctg tcatcggaat aaccgccaca ggaatctgtc
     8401 tatcttttag tttttcttga aagtccccta gtaaatagcg aacttgagga cctaaaagca
     8461 acacatttac ttcctttgtt gctacaattt cttctgcttc aggagctgga actgcaaaaa
     8521 tttctgcatc caacccctta tcttctgctg ccttttgcat ctttgtcact agcagacttg
     8581 tactcatacc tgctgcacac gctaacataa ttgttacttt agccataagc ttactccttt
     8641 atcacctatt tactgaccta gccaagcgag atactgtatg tctcactcct ctaattgcct
     8701 tgctcaaggc ataaatatta tcgactgttg ccagtccccc atatcctgcg tcacctatat
     8761 gttgaatatc aactccacaa attttatttc taagtgcaat ttccttgata gtatctgtat
     8821 cagatgtttc ttggctagta ccaatagcac tcaatacaag accaccctta ctatgaacga
     8881 gatcaacgac ttcacgcaac tcttggtcat gaaaggctgg aacggttcca actgctggaa
     8941 caagtatcac atccgcacct gcttccaaca attgctctgc gacagaaagc tctgccacag
     9001 gctcattcac tcctgccccg tgcatcttac ctgcaataat caaaccagaa aagttttcct
     9061 tagcagtttg aacagcctta atgatttctc gattgctaac tcctgttcca ggatttccag
     9121 tcaaacagac aaagtcaaaa cctaactcct ctattcgatt caatgtttca acactagcaa
     9181 cacgacctgc aacaatttcc tgtgtttcct ctagcatctt tgcagatggg tcaatcggtt
     9241 ccaaatttac accaattgga caagcaacaa gctggtgtaa gcgatgaata acatcatcac
     9301 ctgaactatc caaagcataa attttaggct caaaaacatc aacacaattc aataaaatca
     9361 tatcagctcc aaaagctcta gcaatttcag aattagttat atccccaaca aatgtctcac
     9421 gagtaactac attttcagat agaacaactc taccttcact tgctaaaata ctttgtttta
     9481 attcttcagc attcatctgt aatatctcag atggatttgc actaattaaa cgtttcattc
     9541 tcaatcctcc aataacttaa accgtttttc aatagctatt acaaatggta aataaagtaa
     9601 gacatccaaa acaatcaata caatttgtaa taatgaacca gaaatacttc ctgtagcaag
     9661 taaaccactt ataacaggtg gcatagtcca acctggatct gtataagtta gcggaaccaa
     9721 acctgatgcc attgctcccc acgctactag taagttaaac attggagcta agataaatgg
     9781 aactagtaac aaaatgttca aaacaatagg aacgccaaac attgctggtt catttatatt
     9841 aaataatcca ggtataacag ttataggtgc caaagttttt agttgtttac tagctttctt
     9901 cttatgtgct aaatatccta acgcaagaac taaacctatg gttgcaccac cgccacctat
     9961 gaatacaaaa ttatccataa atacgctagt aaaaatattt ggaagagttt ctccagtttg
    10021 ataagctact ttatttgcat ctagattagc taaccataac ggtttcataa ctgcattaac
    10081 aacatttcct ccgtgtaatc ctacaaacca aaaactacta ttaaggaaaa ttaagataag
    10141 aagaccaata acattatttc ctaaaagtcc aagtggacct cccaaagcta cttgagcaat
    10201 ttcatgaaga ttaggtaaac ttaatttatc taaagttgca taaacaatca accaaccaac
    10261 aatagtcact gcaccaggaa taatggcact aaagctttta gatactgctg gtggaacacc
    10321 atccggcatt tttatctgta tattatgatt tataaaccat tggtagatat agccattaat
    10381 caatcctaaa atcatagcaa caaataaacc ttttgatgcc atgaaagcgg taggcattcc
    10441 tgctccagcc tctcctctaa tgaaaggcgt aactgtaata aaagatgata atgacacaat
    10501 accagcagga ataccatcaa ctttgtattg tctagccata aagtaagcga taccaaaact
    10561 agctacaaga ccaagtaatc caaaactact atcaacaccc ttccataaat agtcagcaac
    10621 accaatatca cccagatatt tttcccatcc tggaatagga aaacttgcaa taaccattag
    10681 taatgaacct atcaacaata aaggtatagt tagagtaata ccgtctcgaa tagaaaccaa
    10741 cgctttatta ttacccaatc tagccgctac tggaagtaac ttttcttgta ataatttttc
    10801 cataaccttt tcctcttaaa tatattttat tatcaaaagt tatcaattat ctttattttt
    10861 tgacgtcaag ttgttatttg attatctttt gttatttata ttttacaact ataagaaagc
    10921 cttgtcaagg atttgtgtaa acatttga
//
LOCUS       DBEJJE010000059        10852 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEJJE010000059 DBEJJE010000000
VERSION     DBEJJE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.59"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            147..302
                     /locus_tag="ACL3F5_001812"
                     /pseudo
     CDS             147..302
                     /locus_tag="ACL3F5_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            502..3777
                     /gene="rexB"
                     /locus_tag="ACL3F5_001813"
     CDS             502..3777
                     /gene="rexB"
                     /locus_tag="ACL3F5_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0515570.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3774..7424
                     /gene="addA"
                     /locus_tag="ACL3F5_001814"
     CDS             3774..7424
                     /gene="addA"
                     /locus_tag="ACL3F5_001814"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0515571.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVPISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLN
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7639..8817
                     /locus_tag="ACL3F5_001815"
     CDS             7639..8817
                     /locus_tag="ACL3F5_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515572.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9026..>10852
                     /gene="iga"
                     /locus_tag="ACL3F5_001816"
     CDS             9026..>10852
                     /gene="iga"
                     /locus_tag="ACL3F5_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGR0515573.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPIKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKPKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPENNDSKNENSEKTGEEVPVNPNEGTVEGTSNQE"
BASE COUNT         3514 a         2179 c         2272 g         2887 t
ORIGIN      
        1 ctatttttgg ttcattttac tatattagat tgaaataaga tacgaacagc ttgattaggg
       61 aaatcaaatt aatttctaga aatattttag catccacggt gtactgttat agtttcaatt
      121 tactatagtt caatcattct atcaagaata ttgaatatat aaaggcacgt aatattaaaa
      181 cttcttctga tatcgaatta gagtccgatg ttgatggcga taaatcagac aatctacccg
      241 tcgacattaa gatactggga caacacattg aagtgtattc cgtacctaag aaacaatcat
      301 aaaactcaaa gccttgttac cgaggctttt ttattatgtg attttcagta gccagactta
      361 ttctatctaa tacaagtaaa gctaagtatt taagatttag cagatgatga agaaaagaaa
      421 ggatggccta aatattttaa cagatttacg aggctaatca tggtataata tagggtgatg
      481 aaaaattcca acgaggctga gatgaaatta ctttatactg atattcggac ttctttgaca
      541 gaaattctaa caagagaggc agaagagcta gttgcagctg gcaagcgggt cttctacatt
      601 gcccccaact ctctttcttt tgaaaaggaa cgcgccgtgc tggaatactt gtcccagcag
      661 gcttcttttt cgattaccgt cacgcgcttt gctcaaatgg ctcgttatct ggtcttgaat
      721 gatttaccag ttaaaactac tcttgatgat atcggtcttg ggttggcctt ttacaaatgc
      781 cttgccgaac tcgatcccaa ggacttgcgt gtttatggcg ctattaagca ggatcctcaa
      841 ttgatccagc agttaattga gctttaccat gagatgacca aatctcagat gagttttttg
      901 gacttggaga atttaacaga tgaggataag aggacggatt tactcttgat ttttgagaaa
      961 gtaacagcct atcttaatca aggtcagtta gcccagggaa gtcagttgtc ccatttgatt
     1021 gaggctattg agaatgacaa ggtaagtagt gattttaatc aaatcacctt ggtcattgac
     1081 ggctttactc gtttttctgc tgaggaagag cgggttgtgg acttacttca cggcaaaggt
     1141 gttgagattg ttatcggggc ttatgctagt aagaaagcct ataccagtcc ttttagcgag
     1201 ggcaatctct accaagccag cgtaaaattt ctccatcatc tggcttctaa ataccaaacg
     1261 cctgctcagg actgttctca aactcatgag aagatggata gttttgacaa ggcctctcgt
     1321 ttgttggagt cttcttatga cttttcagaa ctcgctttgg atgtcgatga gaaagaccgt
     1381 gaaaatttac aaatctggtc ttgtttgacg caaaaggagg agttggagct agtagcccgt
     1441 agcattcgtc agaaattaca tgagaactca gacctgagct acaagcattt tcgtattctc
     1501 ttgggggatg tagcttctta ccagttatct ctcaaaacca tttttgacca gtatcagatt
     1561 cctttttatc ttggtagaag cgaagccatg gctcatcatc ccttgactca gtttgtcgag
     1621 tctattttag ctttaaaacg ttaccgtttt cgtcaggagg acttgattaa tcttcttaga
     1681 actgatttgt atactgacct cagtcagtct gatattgatg cttttgagca atatatccgc
     1741 tatcttggta tcaatggctt gccagccttt cagcaaacct tcaccaaatc ccaccatgga
     1801 aaatttaatc ttgagcgttt gaatgtcctc cgcctgagaa ttttagcacc tcttgaaacc
     1861 ctctttgcca gccgaaaaca aaaggctgaa aaactcctac aaaaatggag tgtctttcta
     1921 aaagaaggag ctgtgaccaa gcagttacaa gatttgacaa ccactttgga agctgtagaa
     1981 caggaaagac aagccgaagt ttggaaggct ttctgccatg ttttagaaca atttgcgact
     2041 gtttttgctg gttcacaggt tagtctggaa gacttcctag ccttgctcca ttctggaatg
     2101 agtttgtccc aataccgtac cattccagca acagtggaca ctgttctggt gcagagttac
     2161 gatttgattg caccattgac tgctgacttt gtctatgcta ttggactaac tcaggacaat
     2221 ttaccaaaaa tttctcaaaa caccagtctt ctgacagatg aagaaaggca aaacctaaac
     2281 caaacgaccg aagaaggcgt tcaattactg attgccagca gtgaaaatct caagaaaaat
     2341 cgctacacta tgctttcctt ggtcaattct gctcgtaagc agttgttctt gtcggctcca
     2401 agccttttta acgaaagtga aagtaaggaa tctgcctatc ttcaagagtt gatccatttt
     2461 ggatttaggc ggagagagaa gaggatgaat cacaaaggac tgtctaagga ggatatgggg
     2521 tcctatcaca gtcttttgtc tagtctggtt gcctatcacc agcagggtga gatgagcgat
     2581 actgagcaag atttgacttt tgtcaaggtt ctgtcgcgtg tcataggtaa aaaactagat
     2641 ctgcaaggtc tggaaaatcc agctatccca accagtccaa gcagcaagac cttagccaag
     2701 gacaccttgc aagctctcta tcctgccaaa caggagtttt acctgtctac gtcgggtttg
     2761 acagagtttt atcgcaatga atacagttat ttcctacgct acgttttagg cttgcaggag
     2821 gaattacgtt tgcgtcctga tgcccgtagt cacgggaatt tcttgcatcg tatctttgaa
     2881 cgcgccttac agttgcctaa tgaagattcc tttgaccaac gtctagaaca agctattcaa
     2941 gaaaccagtc aagaacgcga atttgaagct atttatcaag aaagtttgga agcccagttt
     3001 accaaggaag ttttgcttga tgttgcacgg acgactggac atattctccg acacaatcca
     3061 gccatcgaaa ccatcaaaga agaagcaaat tttggtggaa aagaccaagc ctttattcaa
     3121 ttagacaatg gacgcagtgt ctttgtacga ggcaaggtgg accggattga ccgtttgaaa
     3181 gctaatggag cgataggagt agtagactac aaatccagtc tgactcagtt ccagtttcct
     3241 catttcttta atgggctcaa ttctcagtta ccaacctatc ttgctgccct aaaaagagaa
     3301 ggggagcaga actttttcgg cgccatgtac ttggaaatgg ctgaacctgt ccaatctctg
     3361 atggcggtaa aaagtctggc aggagcagtg gtagaagcca gcaaatctat gaaataccaa
     3421 gggctcttct tggaaaaaga aagcagttat ttaggcgaat tttataacaa aaacaaggct
     3481 aatcaactga cagatgagga atttcagctc ctactggact acaatgccta tctttacaag
     3541 aaagctgctg agaagatttt agcaggccgg ttcgccatca atccttatac tgaaaatggc
     3601 agaagcattg ccccatacgt ccagcaacat caggctatta caggctttga agccaattac
     3661 catctgggcc aagcccgttt cctagaaaaa ttggacctag ctgatggcaa gcgtctggtc
     3721 ggagaaaaac tcaagcaagc ttggtttgaa aaaataagag aggagttaaa tcgatgaagc
     3781 ttattccctt tttaagtgag gaggagattc aaaaactgca agaagcagaa gcaaattcga
     3841 gcaaggaaca gaagaaaact gccgaacaaa tcgaagctat ctacacttct ggtcagaata
     3901 tcctggtctc agcatcggct ggttctggaa agacctttgt catggtagag cgcattctgg
     3961 accaattggc gcgtggtgtc gaaatttctc aactctttat ctcaaccttt accgtcaagg
     4021 ctgcaactga acttaaagaa cgtttagaga aaaaaatcag caagaaaatc caagaaacag
     4081 atgatgtcga tctcaaacaa cacttgggtc gccagttggc agacctaccc aacgctgcca
     4141 tcggaaccat ggactctttc acacaaaaat tccttggcaa acatggttat ctgcttgata
     4201 ttgcacctaa tttccgtatt ttacaaaacc aaagcgagca acttcttctc gaaaacgaag
     4261 tctttcatga ggtctttgaa gcgcattacc aaggtaaaca gaaagagagc tttagtcatt
     4321 tgctgaaaaa ctttgctggg cgtggcaagg acgaacgggg tctgcggcag caagtctata
     4381 aaatctatga cttcctccaa tccaccagta atcctcaaaa gtggctgagt gaatctttcc
     4441 tcaaaggctt tgagaaagct gattttacca gtgaaaaaga aaaactgact gagcaaatca
     4501 aacaagccct ctgggatttg gaaagctttt tccgttacca tctggataac gatgccaagg
     4561 agtttgcaaa ggctgcctat ttagaaaatg ttcagttaat tctggatgaa attggctccc
     4621 taaatcagga gttcgatagt caggcttatc aggcagtact tgcgcgtgtt gtccccatct
     4681 ctaaggagaa aaacggtcgt gctctgacta atgccagccg taaggctgat ttgaagcccc
     4741 tggctgatgc ctacaacgaa gagagaaaga cccagtttac taaactagga caattatcag
     4801 accagatagc gattctcgac tatcaagaac gttatcatgg agacacttgg aaactagcta
     4861 aaaccttcca atctttcatg agcgattttg tagaggctta tcgtcagaga aaacgacagg
     4921 aaaatgcctt tgaattcgct gatatcagcc attacaccat tgagatttta gaaaatttcc
     4981 cacaagttcg tgagtcttat caggagcgct tccatgaagt catggtcgat gagtatcagg
     5041 ataccaacca tattcaagaa cggatgctgg aattgttgtc taatggccac aatcgcttta
     5101 tggtgggaga tatcaagcaa tccatctatc gtttccgtca ggcagacccg cagattttca
     5161 atgagaaatt ccaacgctat gcgcaaaatc cccaagaagg caagctcatt ctcctcaagg
     5221 aaaatttccg tagtagttca gaagtgctgt cagcaaccaa tgatgtcttt gaacgtctca
     5281 tggaccaaga ggtcggcgaa atcaactatg ataacaagca ccagcttgtt tttgccaata
     5341 ccaaactgac tcccaatcca gacaacaagg cagaatttct cctctacgac aaggacgata
     5401 caggtgagga agaagagagt caaacagaaa cgaaactaac aggcgaaatg cgcttagtta
     5461 tcaaggagat tctgaaactt catcaagaaa aaggtgttgc ctttaaggaa attgcccttc
     5521 tgacctccag ccgcagtcgt aatgaccaga ttctcctcgc cctgtctgag tacgggattc
     5581 ctgtcaaaac tgacggagag caaaacaatt atctccaatc cctagaagtg caagtcatgc
     5641 taaacactct tcgtgtcatt cacaatcccc tgcaagacta tgccttggtt gcccttatga
     5701 agtctccaat gtttggtttt gatgaggatg agctagcacg tttgtccctt cagaaagcag
     5761 aggataaagt ccacgaaaat ctctatgaga aactggtcaa tgcacaaaaa atggcaagta
     5821 gtcaaaaagg cttgattcac acagctctag ctgaaaaact aaagcaattc atggatatcc
     5881 tagcttcttg gcgcttgtat gccaaaaccc actctctcta tgacttgatt tggaagattt
     5941 acaacgaccg tttttattat gactatgttg gggctttgcc gaatggtcct gctaggcagg
     6001 ccaatctcta tgccctagca ttgcgtgctg atcaatttga aaagagcaat ttcaaaggtt
     6061 tgtcgcgttt tattcgtatg attgaccaag tcttagaagc ccagcacgat ttggcaagcg
     6121 tggccgtcgc accgccaaaa gatgcagtag agctcatgac catccacaag agtaaagggc
     6181 tggagtttcc ttacgtcttt atcctcaata tggatcaaga tttcaacaag caagactcta
     6241 tgtcagaagt cattctcagt cgtcagaatg gtcttggtgt caaatatatt gccaagatgg
     6301 agacaggggc agtagaagac cactatccta aaaccatcaa actctccatt cctagtctga
     6361 cctataggca gaacgaagag gaattacagc tagcaagcta ttctgagcag atgcgtttgc
     6421 tgtatgttgc tatgacgcgg gctgagaaaa agctctatct tgtcggcaag ggttctcgtg
     6481 aaaagctgga agtcaagcaa tacccagcag ccaaaaatgg gaaactaaat agcaatacta
     6541 gactgcaagc acggaatttc caagattggc tttgggctat cagtaaagtg tttactaagg
     6601 acaagctcaa ctttagttat cgttttattg gcgaagatca gttgaccaga gaagctatcg
     6661 gagagttgga aaccaagagt cctctccaag atagctccca agcagacaat cgtcagtcag
     6721 ataccatcaa agaagctctg gaaatgctga aggaggtgga agtttataat actcttcacc
     6781 gcgcagctat tgaacttcct agtgttcaaa ccccaagtca aatcaagaaa ttctacgaac
     6841 cagttatgga tatggaaggt gtcgagattg ctggtcaagg tcagtcagta ggcaagaaaa
     6901 tcagcttcga tttgccagat ttttcaacca aagaaaaggt aactggagct gagattggta
     6961 gtgctactca cgaactcatg cagagaattg acctcagcca gcaactaacc cttgctagcc
     7021 taacagaaac actcaaacaa gttcaaacta gccaagctgt cagagacaag atcaatcttg
     7081 ataaaattct tgctttcttt gacacagtac tcggtcagga aattcttgct aataccgacc
     7141 atctctatcg cgagcaacct ttctccatgc tcaaacgaga ccaaaagagt caggaagact
     7201 ttgttgtccg tggtatcctt gatggctatc tgctttacga aaacaaaatt gttctgttcg
     7261 actacaagac agaccgctat gatgaaccaa gtcaactcgt agaccgctat cgtggtcagt
     7321 tagctctata cgaagaggct ttatcacgag cctattcgat tgaaaatatt gaaaaatact
     7381 tgattttact cggtaaagac gaggttcaag ttgtaaaagt ataacttata ctctttgaaa
     7441 atctcttcaa accacgtcag cttcgccttg ctgtatatat ggttactgac ttcgtcagtt
     7501 ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc tacaacctca
     7561 aaacagtgtt ttgagctgac tgcgactagc tttctagttt gctctttgat ttttattgag
     7621 tattagaaag gagacctcat gacacttcca gttagaaaat ccctgcacga tgcagtttta
     7681 caggcttcga aagcggatac ttgggaacaa gctaccaagg aatggaatga agtttccttg
     7741 atttttaacg gtatcggccg tagcaattgt gtctgtggaa atgccatcaa atacgcttat
     7801 gaactcttta acggtgtcac aggccaacgc ctctttccaa ttggtagcga ctgtgttcgt
     7861 cattttcatc gattgtccct tgaccagcaa ttggaagagg aagaaaaact gctcagaaag
     7921 gttgaaaatc taaccagaaa agctcagaaa aaggaaaaaa tcaaggtcaa taaaagtgac
     7981 tttgacgagc gacttctaaa atggctctgg gaaaaaggtg ttttcaaacc caatcgtggc
     8041 aatcaatttg cgcctgagag agactgccag cttttcctag aagtctttca gggaggaagt
     8101 tggaccaagg cggaaccaaa gaaaaaggct cggatggaag aagtccttga aaagtgtatc
     8161 aaaccctttt tacttgggaa atcggatgac caactctacc ttgtcaagct aggcaaggag
     8221 aaaattgact acgaacaaga actccgtatc caggcagaga aagaacgcaa gaagagggat
     8281 aaaatcgcca agcaatatgc agacaatctg gttctagcca tgggacccgc agagcgtgct
     8341 tatcaagatt actttggctt tacagagacc ctgactcaag aagaacgcaa gtgggaaaaa
     8401 attctttttg gtaaaaatag agcagaacgg gctatcaagg ccaaacaata ccaaaaagag
     8461 ctggaaaaag accaacgaat tgccagtcag gatccaattg aaagaaaaca gaagcagact
     8521 tggctcctca attcctattt tcgtgagctt cctgaagaaa aagctcgatt ttctaggctc
     8581 ttattagaat atcgaaaaaa tggtgaagta cccttttcaa ctgaatacct gtcagatcat
     8641 ctcatcgact ttttctataa aatgaaagcc tttgaatttg aaatcgcacc agaacaagtc
     8701 cgagattttc taaaaaaaag cctgcaggaa gaccatcgct catcagcaca aggaagctgg
     8761 atagaaggaa ttctcctcaa ctgcctcaaa ccatttttag aacgattagt gatatgagta
     8821 acacctaccg tgtaaatttc atggtaggtg ttattgtacc tcaaaataat ataaaacaaa
     8881 gtatgaaagc gcatctcaat tttaagactt ttttgtaaat taagagtata attaaggtat
     8941 actgcctttt ctatagataa tagataatac actaatataa taaaggtctt tgtaacatat
     9001 ataaatttta tttcaaggag gaataatgga aaagtatttt ggtgaaaaac aagagcgttt
     9061 ttcatttaga aaattatcag taggacttgt atctgcaacg atttcaagtt tattttttat
     9121 gtctgtatta gctagttcat ctgtggatgc tcaagaaact gcgggagttc actataaata
     9181 tgtggcagat tcagagctat catcagaaga aaagaagcag cttgtctatg atattccgac
     9241 atacgtggag aatgatgatg aaacttatta tcttgtttat aagttaaatt ctcaaaatca
     9301 actggcggaa ttaccaaata ctggaagcaa gaatgagagg caagccctag ttgctggtgc
     9361 tagcttagct gctctgggaa ttttaatttt tgctgtttcc aagaaaaagg ttaagaataa
     9421 aacggtatta catttagtat tggttgcggg aataggaaat ggtgtcttag tttcagtcca
     9481 tgctttagaa aatcatcttt tgctaaatta caatacggac tatgaattga cctctggaga
     9541 aaaattacct cttcctaaag agatttcagg ttacacttat attggatata tcaaagaggg
     9601 aaaaacgact tctgattttg aagtaagtaa tcaagaaaaa tcagcagcca ctcctataaa
     9661 acaacaaaag gtggattata atgttacacc aaattttgta gaccatccat caacagtaca
     9721 agctattcag gaacaaacac ctgtttcttc aactaagccg acagaagttc aagtagttga
     9781 aaaacctttc tctactgaat taatcaatcc aagaaaagaa gagaaacaat cttcagattc
     9841 tcaagaacaa ttagccgaac ataagaatct agaaacgaag aaagaggaga agatttctcc
     9901 aaaagaaaag actggggtaa atacattaaa tccacaggat gaagttttat caggtcaatt
     9961 gaacaaacct gaactcttat atcgtgagga aactatagag acaaaaatag attttcaaga
    10021 agaaattcaa gaaaatcctg atttagctga aggaactgta agagtaaaac aagaaggtaa
    10081 attaggtaag aaagttgaaa tcgtcagaat attctctgta aacaaggaag aagtttcgcg
    10141 agaaattgtt tcaacttcaa cgactgcgcc tagtccaaga atagtcgaaa aaggtactaa
    10201 aaaaactcaa gttataaagg aacaacctga gactggtgta gaacataagg acgtacagtc
    10261 tggagctatt gttgaacccg caattcagcc tgagttgccc gaagcagtag taagtgataa
    10321 aggcgtacca gaagttcaac cagcgttatc ggaagcagtc gtaaccgaca aaggtgagcc
    10381 cgctgtccaa ccagagctac cggaagcagt tgtaagtgat aaaggtgaac cagagcaggt
    10441 agccccattg ccagaatata aggggaatat tgagcaagta aaacctgaaa ctccggttga
    10501 gaagccgaaa gaacaaggtc cagaaaaaac tgaagaagtt ccagtaaaac caacagaaga
    10561 aacaccagta aatccaaatg aaggtactac agaaggaacc tcaattcaag gagcagaaaa
    10621 tccagttcaa cctgcagaag aatcaacaac gaattcagag aaagtatcac cagatacatc
    10681 tagcgaaaat actggggaag tgtccagtaa tcctagtgat tcgacaacct cagttggaga
    10741 atcaaataaa ccagaaaata atgactctaa aaatgaaaat tcagaaaaaa ctggagaaga
    10801 agttccagta aatccaaatg aaggcacagt agaaggtacc tcaaatcaag aa
//
LOCUS       DBEJJE010000060        10756 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEJJE010000060 DBEJJE010000000
VERSION     DBEJJE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.60"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(117..1541)
                     /locus_tag="ACL3F5_001817"
     CDS             complement(117..1541)
                     /locus_tag="ACL3F5_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0515574.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQKEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL3F5_001818"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL3F5_001818"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0515575.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQTYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLLTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL3F5_001819"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL3F5_001819"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0515576.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="ACL3F5_001820"
     CDS             complement(6528..7706)
                     /locus_tag="ACL3F5_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0515577.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNLFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFSYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="ACL3F5_001821"
     CDS             complement(7786..8649)
                     /locus_tag="ACL3F5_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0515578.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="ACL3F5_001822"
     CDS             complement(8652..10553)
                     /locus_tag="ACL3F5_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0515579.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3228 a         2366 c         1914 g         3248 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataattt
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag aagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttctttc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cctgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaatagggg ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa ttttttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaaatccac
     1681 tacatcaagg cgagactaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagtcaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctattcc aatttcaggc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag accccctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt accaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttagcaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaaag caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagtttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatgt gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagtc ttacctacca aatcttcttc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgtact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatgatca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 atacagattt tcaattgaat gaaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 ggcagggaac ttgtaggcta ctgcccactt tggagcctta actgtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagattttc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 acggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata actaaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtacactt ggcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctctcccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     6961 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaggc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagagat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagattt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgtatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaaag cattttccaa cacttccttg
     9121 ctatcaatat ccaagtggtt ggtcggctcg tcaaggatca ggaagttgtt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc acctttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctaggttaa tcggttgtga caagacttcc
     9541 ccgtcatagc caacagctgc attttcaaca gtcaaaacaa cattgcccga cgttttttca
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaattcg acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggcg
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tggcaagtgc caaacgagta ttttgaccac cagaaagctc agcaattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cacctgcttg gcgaaaattc tcagataagc ggtcataatc tgacatcagt
    10201 ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg cagttgtctc
    10261 tccgtccgac gcaaatcatt aaagacatga agcatttcat cgtagatggt attttcagac
    10321 tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccgctagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagagcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag tcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagtctatta tttaattctt
    10741 ttcattattt acgtac
//
LOCUS       DBEJJE010000061        10126 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEJJE010000061 DBEJJE010000000
VERSION     DBEJJE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.61"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..340
                     /locus_tag="ACL3F5_001823"
     CDS             <1..340
                     /locus_tag="ACL3F5_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0515580.1"
                     /translation="NCLSETTDKNWHKSDRVFVTNTGKTVHSSILSKSLQRANERLKK
                     PIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAIN
                     VLDKVMKKIF"
     gene            complement(478..1782)
                     /gene="eno"
                     /locus_tag="ACL3F5_001824"
     CDS             complement(478..1782)
                     /gene="eno"
                     /locus_tag="ACL3F5_001824"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0515581.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1946..2392
                     /locus_tag="ACL3F5_001825"
     CDS             1946..2392
                     /locus_tag="ACL3F5_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0515582.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2389..3504)
                     /locus_tag="ACL3F5_001826"
     CDS             complement(2389..3504)
                     /locus_tag="ACL3F5_001826"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR0515583.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3513..3842)
                     /locus_tag="ACL3F5_001827"
     CDS             complement(3513..3842)
                     /locus_tag="ACL3F5_001827"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0515584.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3787..4158)
                     /locus_tag="ACL3F5_001828"
     CDS             complement(3787..4158)
                     /locus_tag="ACL3F5_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR0515585.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLRREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4217..5650)
                     /gene="glgA"
                     /locus_tag="ACL3F5_001829"
     CDS             complement(4217..5650)
                     /gene="glgA"
                     /locus_tag="ACL3F5_001829"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0515586.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKTKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5647..6786)
                     /gene="glgD"
                     /locus_tag="ACL3F5_001830"
     CDS             complement(5647..6786)
                     /gene="glgD"
                     /locus_tag="ACL3F5_001830"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0515587.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6776..7918)
                     /locus_tag="ACL3F5_001831"
     CDS             complement(6776..7918)
                     /locus_tag="ACL3F5_001831"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0515588.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7908..9836)
                     /gene="glgB"
                     /locus_tag="ACL3F5_001832"
     CDS             complement(7908..9836)
                     /gene="glgB"
                     /locus_tag="ACL3F5_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0515589.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGYIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVAFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3077 a         2233 c         1785 g         3031 t
ORIGIN      
        1 aaattgtcta agcgaaacaa ccgataagaa ttggcacaaa agcgaccgtg tttttgttac
       61 caatacagga aaaacagttc atagttctat cttgagcaag tctctccagc gagcaaacga
      121 acgccttaaa aaaccaattc ccaaacatct gtcccctcac atcttcagac acaccactat
      181 tagcatctta tcagaaaata aaattccttt aaaaacaatc acggacaggg ttggtcattc
      241 cgactctgaa gtcactactt ccatctacac ccacgtcaca aagaacatga aagatgaagc
      301 aatcaatgta ctggataaag ttatgaaaaa gattttttaa aaagttttgc cccttttttg
      361 tcctctaaat acaaaaatag cccttcggat aaaatccgag gggctagaaa cgttgttaaa
      421 tcaacggccg aacttttgaa tttcatggtt cgggataaaa tagttcactg aactatttta
      481 ttttttaagg ttgtagaatg atttcaatcc acgatattca gctacttcac caagttggtc
      541 ttcgatacga agcaattggt tgtatttagc gatgcggtct gtacgtgaaa gtgaaccagt
      601 cttgatttgt cctgcgttag ttgcaactgc aatatcagcg attgttgaat cttcagtttc
      661 acctgaacgg tgtgatacaa cagcagtgta accagcttct ttagccattt cgatagcttc
      721 aaaagtttca gtaagagtac cgatttggtt aactttgata aggattgagt tagcagcacc
      781 ttcttggata ccacgtgcaa ggtagtcagt gtttgttacg aagaagtcgt caccaacaag
      841 ttgtactttc ttaccaagac gttcagtaag agctttccaa ccatcccagt cgttttcatc
      901 cataccatct tcaatagtga tgattgggta tttgttaacc aattcttcaa ggtagtcgat
      961 ttgttctgca gatgtacgaa cagcagcacc ttcaccttca aatttagtgt agtcgtaaac
     1021 tttacgttct ttatcgtaga attctgatga agcacagtca aatccgataa atacgtcttt
     1081 acctggtaca tatccagcag cttcaatcgc agcaaggata gtttcaacac catcttcagt
     1141 tccttcgaaa cgaggagcga atccaccttc gtcacctacg gcagtttcca aaccacgtga
     1201 tttaaggatt ttcttaagag cgtggaagat ttcagcaccg taacgaaggg cttctttaaa
     1261 tgttggcgca ccaactggca agatcatgaa ctcttggaaa gcgattggag cgtcagagtg
     1321 agaaccaccg ttgatgatgt tcatcattgg agttggaaga actttagtgt tgaatccacc
     1381 aaggtagctg taaagtggga tttcaaggta gtcagcagca gcacgagcta cagcgataga
     1441 cacaccgagg attgcattcg cacccaattt acctttgtta ggagtaccgt caagtgcgat
     1501 catagcacgg tcaatagctt gttgatcacg tacatcgtag ccaatgatag cttcagcaat
     1561 gatgttgttt acgttgtcaa cagctttttg tgtaccaaga ccaccgtaac gagatttgtc
     1621 accgtcgcga agttcaactg cttcgtgttc accagtagaa gctcctgatg gaaccatacc
     1681 acgtccgaaa gcacctgatt cagtgtaaac ttctacttca agtgttgggt taccgcgtga
     1741 gtctaggact tcgcgagcgt aaacatcagt aataattgac attttttact ctccttatga
     1801 gttaaatttt ttacacctct ataatacctt aaaacccctc ctttttcaag aaaaaacgtt
     1861 atctttgtgc aacttttcct taactttata aagtaatcgc tttcttttgt ctgttttatt
     1921 ctaactttta tgatatactg ttttcatgac agatttatca aaacaattac ttgaaaaagc
     1981 tcatggtggg ttaaaaataa atccggatga gcaaagacgc tatcttggta cttttgagga
     2041 aagagttctt ggatatgtag atattgacac agcaaatagc cctcagttag aaaaaggctt
     2101 tttatttatt ttagaaaacc ttcaggaaaa agcaaagcca ctatttgtga agatttcacc
     2161 aactatcgaa tttgataagc aagttttcta cttaaaagaa gcaaaagaaa ctgatagtca
     2221 agccaccata gtatctgaag agcatattac ttctcctttt ggcctggtta ttcatagcaa
     2281 tgcaccagtt caagtagaag aaaaagacct tcgacttgct tttccaaaac tttgggaagt
     2341 taaaaaggaa gaaccagcca aaacatcctt atggaagaaa tggtttagct aaatcttgca
     2401 catatttaat aagtgcccaa tattggcagc cgtgcgctcc agatagagac tggcattttt
     2461 caaactatct tctaaaggtt cacttttctc caaaatagaa aagacagctt ggatattttc
     2521 aaatggtagg ggaggtaaat cttcagcaag actaccgcaa atagcaataa caggaactcc
     2581 aacaggggtt ctttttgcaa cacctatagg cgctttccca gcaaagcttt gactatcaag
     2641 ccttccttct ccaacaacaa ccaagtcagc atctgaaact ttcttattaa agttgattaa
     2701 gtccaagcag gtatcaattc cagacacgat acttgcctga gcaaaggcac acaaaccacc
     2761 agcaaggcct ccacctgctc ctgctccttt aatttctaat gttgcaggtg agaatttttc
     2821 ataaaaatct tggatcgcct gatctacgac tgcaaacata gtcggatgta gacctttttg
     2881 attgccaaaa gtgtaagtcg caccttgatg accacataag ggactcacga catctgctag
     2941 aatatgaatt tgaacacctt caggaatttt atagcaattt tctgttgaaa cagaagctaa
     3001 gtttaataag gattgaccgg aagcaggcaa gacatttcca tccctatcat aaaattgata
     3061 acctaaacca gcagcaatcc ccagtcctcc atcattactg gccgtgccac caacaccgat
     3121 ataaatatct ttaatccctt tagaaatgag atggagaatc aactctccaa taccacaagt
     3181 ttggatttga agtggatttc gtttctctag cggaattttt ccaagaccaa ccaagtcagc
     3241 tacttcaaat agtgccagtt cccctttttg aaaatagcgc atggcttctt tttgtccaaa
     3301 agggtctgtc acttggatcc atttttcttt taggtcaaga gaatgtcgga tagcatctac
     3361 agtaccttct cccccatcac caacagggca gaggagacat tctacatctg ctatcgattg
     3421 ttggaagcct ctttttattg cttcagctac ctgttgagct gtcaagcttt ccttaaacga
     3481 atccggtgca attacaatct tcatattttc cctcattcta aacagtcaat caaaggaaga
     3541 acttctaaaa aatccctctt gtcaacatga tgtggtattt cttttttgag catttctttg
     3601 gaacaaaagg cgattcctaa ctccgccgac ttcaacatta atagattatt gaccccatca
     3661 ccgattgcca ccgttctttc tttagaaagt tttagtttct ttctccattt ttccagagtt
     3721 tcttttttga cctggggact tataatttgt ccaactaatt ttcctgttaa aagaccttct
     3781 ttgacttcaa gctggttggc agtgaaatag gcaataccaa gggattttgc taatctctcc
     3841 aactattggt gtaaatccac cagacaccag accaactagg atgccattct tttggagaat
     3901 agagatgaac tctgggacat ttagcgatag atgaattgag ttgaagacgt tatcaaagac
     3961 caaaatagga agaccttcca acaaggacac tctttttctt aaactgcttt caaagaccaa
     4021 ctctcctcgc atcgctcgac ttgtaatctg cgaaatttcc gcctcatgac ctgcctctct
     4081 ccttaaaaga tcaatcactt cttctaggat taaggttcca tctacatcca aaacacacaa
     4141 gccttttact tgagacatca gttctcctct ctaaacagcc taaaaatcgt atgaagtcat
     4201 catacgattt tatctattaa ttaactaaac tatggtacaa gtcaaggtat gacttgcagg
     4261 ctgtatccca tgagaagtca ctctccatag cttgtttttg taggtttctc caaatgtctg
     4321 gatggtttct atacaagtcc aatgctgttt ggaaagtcca atttaaccaa taaggagata
     4381 gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg attgaaagcg cgaactgtat
     4441 ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc ataacgcata gccatcattt
     4501 gagacaagcc acacggttca aaacgacttg gcatgaggaa gaggtcacaa gcagcgtaga
     4561 tttcctgagc aagtttgaca tcaaaagtga tatttgttga tagcttgtct gggtaaatct
     4621 gagcaaacca tgagaaagct ccttcaaagg ctggatcgcc agttcccaaa agaacaatct
     4681 gaacatcttc ttgcaagata tggtgaagac tttcgaccac cacatcaaaa cctttttgac
     4741 gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc tctaacaggc aagccaactc
     4801 tttcttgcaa ttttgtctta tttttggctt tcccagacaa atcttcctga ttgaaatgat
     4861 agtctaaaag agcatccgtc tgaggattat aaagatcagc atcaatccca ttcacgatac
     4921 cagatacttt accagactcc attttaagaa tctgatccaa attacatcca aactgactag
     4981 tcataatttc atgagcatag ctaggtgaaa cggttgaaac acggttcgca tagagaatac
     5041 ctgccttcat ccagttcaga cagttgttcc atcgaagggt gccatcagcg taacgttcaa
     5101 agccaactcc aaacaaatca cccaacattc cttctgaaaa ttgtccttgg aattctaaat
     5161 tatgaatggt taaaactgtt tcaatgtcct cataggcttg aatccaacgg tatttttcct
     5221 tcaacaagaa aggaatcata gctgtatggt agtcatgaac atggagaaga tcaggaataa
     5281 agtcaatcct ttccatagcc tcaatggcag ccagttggaa aaaggcaaag cgttctccgt
     5341 catcaaaatc accgtaaaca tgaccacgga agaaataata ttgattgtca ataaagtaga
     5401 aggttacacc atttaatact gttttcttaa ttccacaata ctgtctgcgc caaccaacgc
     5461 tcacctcaaa atgaagcaca tcttcaatct gatttccaaa tttagcctct accatatcat
     5521 agtagggtaa aatcactgca acttcgtgcc cagcttttac cagtgatttt ggaagagcgc
     5581 caatgacgtc tcccaaacca cctgtttttg aaaagggtgc accctctgct gctacaaata
     5641 aaattttcat gaatgaatat cctctgttac tttagcacct ttcttaacca caactggatg
     5701 ttctgcagtt cctcgaatca caacaccagg ctcaacttca acccctttgt ccaagatagc
     5761 atattcgacc tgagcccctt ctccaataac aacacgaggg aagagcaggc tatctttaac
     5821 caagctatcc ttatggacat gaatattacg tgatagaaca gaattagcta cttgaccttc
     5881 aataatacta ccagaggcaa actgagaagt gcttacctta gatgtattag catagtaagt
     5941 tggctcttcg tttttgacct ttgtataaat cttttggttt ggtgagaaaa gagaatagaa
     6001 tttttgtgat tcaagcatat cgatattcgc ttgataataa gatttaacag agtgaatatt
     6061 ggctagatag cccgtgtact cgtaggcgaa agctccctct tttacagcca aatcccgtaa
     6121 aacatagcgc aatttctttg gatgttcttt tttagcttct tcttccaagt gttcaatcaa
     6181 ccaaggtgta tcaacgacaa agatatctgt agacatattg aacgtttcag ctgttgactt
     6241 gctatcaaag agtttatgag aaagaacatg gtctgtttca tctacatcca agattgcatt
     6301 tacttctgaa atatctttct tagctagttt tttataaact acagtgatag gctcttttgt
     6361 tgtactatgt aggtggaaaa cttggttcaa atcaatgtta ataagaacat cgcagttgag
     6421 ggcaaccgtt tggtttgagc cagaacgttt caaataagta agaagctgtt ggtagtattc
     6481 ttttccaact gtactacttt ctacacgggt attgtaaatt cctagatagt aatgactaag
     6541 aagggttgat aagccccact cgcgtcctga acgaatatgg tcaaatactg agctgatatt
     6601 atcctgctgg aaaataccaa agacactacg aacacctgca ttagcaaggc ttgaaagtgg
     6661 gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt gctactggac ggtggtccgt
     6721 caatgtcgac atattgtgaa aaccaactgt atttcctaaa atggcagaat atttatcaat
     6781 cttcatctgt tgctaccccc actacttcat tatatcctac aacttgtact tcatctgttc
     6841 catcaatttc gacaccgtca gaaataatcg caccttcacc aataatggca cgtttaatct
     6901 tagctccttg accaatgata gctccactca tgataactga atcaaggact tccgctcctt
     6961 cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac agttccatca acgaaacatc
     7021 cgtctacaac taatgagtct tccacatgag catttgcccc gaggaagttt ggtggtgaaa
     7081 tcaagtttct tgagtaaatc ttccattgac ggttacgact atccaaggca ttttctggag
     7141 aaatatactc catgttcgct tcccaaagtg actcaatagt accaacatct ttccaataac
     7201 cactaaattc gtaagcataa acactttcac ctgactcaag gtaatttgga atgacatttt
     7261 taccaaagtc tgacatgcca accttgctct tttcagcagc gactaacata ttacgaaggc
     7321 gttgccaatc aaaaatgtag attcccatag aagcttttgt agatttaggt tgagctggtt
     7381 tttcttcaaa ttcaacaata cgattgttag catctgtgtt catgatacca aaacggcttg
     7441 cttctttaag agggacgtct aaaactgcta ctgtcaagct ggcattatta tccttatgag
     7501 actggagcat atcatcatag tccattttgt agatgtgatc cccagacaaa atcaagacat
     7561 actcaggatt gacactgtcg atatagtcga tattttggta aatagcgtga ctagtcccct
     7621 caaaccaacg atttccttca cttgcagaat aaggttgaag aatagagaca cctgaattaa
     7681 taccgtctag tccccagctt gaaccattcc caatatggtt gttgagagca agtggttgat
     7741 actgtgtaac gaccccaaca ttgtgaatcc ctgagttggc acagtttgat agggcaaagt
     7801 caatgatacg gtagcgccca ccaaattgca cagctggttt tgcgatgctt tgagtgagtt
     7861 taccgagacg agttccttgc ccaccagcaa gaatcaaagc taacatttca tttttcattt
     7921 tctactcctt tttggttttt atttgtgacg gttttagtag atttcaagcg acgtttgatt
     7981 ttccatacac ttgctcccat agccggtagg gtaaaggtta aggtctgctc ataatctttc
     8041 catagtcctt cttgcgtttg aacagtttga ttatgttctt tccaaacgcc tccccactct
     8101 tccaactcag tattccatac ttcttcgtaa attcctgcaa cgggtagtcc gattgtaaaa
     8161 tctttccgct caacaggtac catgttaaag atacagacta acatttctcc ctttttaccc
     8221 ttacgaataa aggaaagaac actctggtct cgattatccg catcaatgat ttcaatacca
     8281 tcatagctgg tatcgatttc ccacagacag cgatgatctt tgtaaaactg gtttagctga
     8341 gaagtgaaat acttcatctt agcattcatt gggtcttcta ggttagacca ttccaactgt
     8401 tcttcagatt tccattctag gaattgaccg tattcgctac ccatgaagag caatttctta
     8461 ccaggatgac aaatttggta cgtatagaga ttgcgcaagc ctgcgaattg attgtaacga
     8521 tctccccaca tcttatgcat catactcttc ttgccatgaa ccacttcatc gtgcgagaat
     8581 ggcaagagat aattctcctt gaaaacatac ataaagctga aagccaccag gttaaagtca
     8641 tatttacgat agatcggatc ttcttcgtag aaacggagga tatcattcat ccagcccatg
     8701 ttccatttgt agtcaaatcc tagaccacca atctctttca ttcccgtaat cttggtcgca
     8761 gacgaacttt cttctgcaat catcatcaca tctggatatt ctaacttaat aacctcattc
     8821 aagcgttgaa ggaaataata accttcatag ttgagatttc cgccatcttt attaggtgtc
     8881 catggagcat catcatagtc caaatagagc atgttgctaa cagcatccac acgaatacca
     8941 tccaaatgat agacatcaat ccaatgctta atgcaagaaa ttaagaagga ctggacttca
     9001 ttttttccaa ggtcaaaatt aagggcaccc caaccatggt tatgagcctt attatggtct
     9061 tggtattcaa aagtcggtgt cccatcataa taggctaagg catcatcgtt gatggtaaag
     9121 tgacctggta cccagtccac aataacccca atattatggg tatgacactc ctcgacaaaa
     9181 tcttgaaact cctctggtcg gccataagca tgctctaaag cgaagtaacc cataagctga
     9241 tacccccaac tcaagcccaa aggatgggac atcaagggca taaactcaat atgagtatag
     9301 ttcatttcaa cgagataagg aatgagttca tccttgagct gggcaaaact ataaggactg
     9361 ccatcagaat ttcttttcca tgatccagcg tgaacttcat aaatattgac aggacgctct
     9421 tcaaagcccc aacgttttct tcgtgccagc caaagtccat ccttccattt cttctcagga
     9481 agctctgtta agattgcccc tgttcctgga cgagcctcat acctgacagc aaaagggtca
     9541 atcttcatca gttgatgacc attttgacgt gtgacatgat atttgtaaat atacccttct
     9601 tgagccatat tggtaaagac ttcccagacc ccaaaatcat ttcttaccat tggaatctga
     9661 ttttcaatcc agttggtaaa atcaccaacc aagtgaacag cctgagcatt aggtgcccaa
     9721 acacggaagg tatagccatg ctctccattt agttcttccc tatgtgctcc tagataatgt
     9781 tggagataaa aattttcacc cgtcataaag gtttttaatg cttctctatt atccatatac
     9841 tccccttctc ctgtaagcgt tttctatgtt tttattatac taccttttta gagaagattc
     9901 aagtaaatta ctatacttct ttaattattt tgaaaatcta caacaagttc acttactcgt
     9961 tcaattgtaa atcaatattt tttcaaaaaa ttgcgaaaac gcctttcttt ttctactata
    10021 gtgaaatgaa ataaaacatg cgcaagtcga ttaaggaatt taatctaatt tctaacaatg
    10081 tcttagaaat caaagtgtac tattttaact tcaatgtact atatat
//
LOCUS       DBEJJE010000062         9821 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEJJE010000062 DBEJJE010000000
VERSION     DBEJJE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.62"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            247..342
                     /locus_tag="ACL3F5_001833"
                     /pseudo
     CDS             247..342
                     /locus_tag="ACL3F5_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(595..1215)
                     /locus_tag="ACL3F5_001834"
     CDS             complement(595..1215)
                     /locus_tag="ACL3F5_001834"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0515590.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(1215..1697)
                     /locus_tag="ACL3F5_001835"
     CDS             complement(1215..1697)
                     /locus_tag="ACL3F5_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0515591.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMILQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1697..2539)
                     /locus_tag="ACL3F5_001836"
     CDS             complement(1697..2539)
                     /locus_tag="ACL3F5_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0515592.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2634..3434)
                     /locus_tag="ACL3F5_001837"
     CDS             complement(2634..3434)
                     /locus_tag="ACL3F5_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0515593.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3578..4957
                     /gene="glmU"
                     /locus_tag="ACL3F5_001838"
     CDS             3578..4957
                     /gene="glmU"
                     /locus_tag="ACL3F5_001838"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0515594.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4967..5512
                     /locus_tag="ACL3F5_001839"
     CDS             4967..5512
                     /locus_tag="ACL3F5_001839"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0515595.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5524..5838
                     /gene="macP"
                     /locus_tag="ACL3F5_001840"
     CDS             5524..5838
                     /gene="macP"
                     /locus_tag="ACL3F5_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0515596.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5855..6547
                     /locus_tag="ACL3F5_001841"
     CDS             5855..6547
                     /locus_tag="ACL3F5_001841"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0515597.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            6624..7115
                     /gene="rocS"
                     /locus_tag="ACL3F5_001842"
     CDS             6624..7115
                     /gene="rocS"
                     /locus_tag="ACL3F5_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0515598.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7213..7803
                     /locus_tag="ACL3F5_001843"
     CDS             7213..7803
                     /locus_tag="ACL3F5_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0515599.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7812..9575
                     /locus_tag="ACL3F5_001844"
     CDS             7812..9575
                     /locus_tag="ACL3F5_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR0515600.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3042 a         1698 c         2088 g         2993 t
ORIGIN      
        1 gtctaacttt tggggtgtag ttcatgtaca cctgatatga tgcgttttat aattttaaag
       61 actttttgac cagcctcatt tttttaactt gatactcagt gaaaagcaaa gattaaacta
      121 ggaagctagc tgtaggctgc tcaaagaaca gctttgaggt tgtagataaa acttgtgagg
      181 tcaccaacat atataatgtg aagctgacgt ggtttgaata gattttagaa gagtatgagt
      241 ctggaagttt taatggataa tgcaagattc catagaatgg gtaagctaga gttcttatgt
      301 gaagagtttg ggcataaact tttacctttt cctccctact catcttagta tagaaaagtg
      361 aatctgaaat agtacataac tgcttctaaa acattcttat aaattgattt aaattctcaa
      421 atcatattat tcagttctta tttcattttg ttctacaatc ctgttgagaa gacacgtgtt
      481 catatcaaaa aggtattggc aagttgcaat acctttttac gaggctctgt tgtcttattt
      541 ttgtttcaac tgactatatc tcctatggtt ctagttcaga aggctaggct ataattatga
      601 ttgataagaa gtatcattcc aagtattggg agtgaatgtt tcaaaatcat gggtttctat
      661 aatggtcagg ctggcatttg ctagaccgcc atctttacga agaagtggtt ctttatagcc
      721 taggagagta cgaagactgg cagtaagatt ggcgccgtgt ccgacaatta gaatacgttc
      781 agctggacta tcttttaatg atttgataaa ttggatggtc cgttgagttg tactatagag
      841 ggattcggct ccgaacattc gagtgtcaaa ttgagcaaga tttgaacgaa aagcctggat
      901 ttgttgcggg taaatagctt ccaaggttgc aattttcaaa ccttctaact tcccaagttg
      961 ccattcacgg agattaggaa cgatttctaa agaacagggg gtatagagtt gactttggat
     1021 aatctcagca gatttgaccg ctcgaggtaa atcacttgaa taaatctgat caaaaggaat
     1081 ttccttgaga tactgaccaa gtcgttttag ggtttcaatg gattcaggaa gaagaggaga
     1141 atcaccacta gcaccttgaa aacgaccttc ttggttccag agggtacgac cgtggcggac
     1201 aaagtagagt ttcattactt gatgtcctcc aaaatatcta caaagtctgc ctttacaaag
     1261 ctagccaagt cttgtggcgc gacgataatg ctgtgtccga cttcgcctgc agagacaatc
     1321 atttgatcca aatctagagc aattttatcg ataaaaatgg gataattgtg tttctgacga
     1381 attccgacag gattattggc tccatgaatg taaccagttg ttttttctaa gtccttttgt
     1441 agaatcatgc tcactttttt attgccagaa attttagcta gtttcttttc agacaagtgc
     1501 tgagtgatag ggacaattcc gataatcggt ccggtcttgt ctcccaaaag cgccaaggtt
     1561 ttgaaaatct gatctcgttc ataaccttga ggaagctctc cttctagggc attgatttga
     1621 atcccctgat gagggatagc tgctttagat aggatttgtt ccaccaatgt ttttttgatt
     1681 ttaacttttt ttgccattat ttatatttat cctccaattg actcatccaa ataccaagcc
     1741 agattcccag cgcaaagaag aaggcgatga tgacataacc gacaagtgaa agtcctgtgt
     1801 attggatact ttcagcgttt cctgcatttg gaattaagat caaaagggta cttgatagga
     1861 cgataccgat gatgaaatga tagacacgtg agtggtagtt gtttaaggca taatccatca
     1921 attttgaaaa aacgatgaga gttgcacctg caccaattcc aatcggaaag aaggttccca
     1981 agaaatcaaa agttttaaaa ccagtcaaca taggagcata gagtcccaaa atcaaaagta
     2041 aatttgatgg gctgaggcca ggaaccaaga cgccaagggc caatagtgcg cctgctagga
     2101 cgaagttaag aaagctggcg cttaaggttc caacgacaaa atttaaggca tagagtccta
     2161 atccagaaat gataaaggtt gtccataacc aagctaaatc aatcttgtct cggtcagatt
     2221 ctcgagttga ttctttgagg aggctaggaa ctgtaccgat aatagctccc gcaaagctcc
     2281 ataatacaaa aacctgataa ttttcaagca ggtattcaat cgggtaggaa aataagccga
     2341 ttcccagaag cataccgatg gcaactggaa taaagtacaa aacattttct ttaaagtctt
     2401 taaagggatg ggccagaaag ccaatcattc gttcatagat tcctaagatt gctgctagaa
     2461 cccctccgga aattcccggt aggataaatc caagagcaat tacaatccct ttaataacgc
     2521 gtgctaacca tgagagcata tatttcctcc aactatttct atttcaaaaa atccttacta
     2581 tattgtatca caatcagaca caaaaagaaa aagcaaatga taaacaaatg cttttaaggt
     2641 tttaaaaaaa gttttcgaaa ggtttcttct ttatttttta agggagagat aacgttgata
     2701 tctaaatcgt ggtcaaagcc ggcaattttt cctttagatg tgtattggtg aatatcataa
     2761 tctaaatcag ttttaggact gctctccaaa aatcctgagt ctgagccgta ggacggaatc
     2821 caaacagagg taaacttgcc tgtatcaata ctgtgttctt ccatgaagta gacaccaacg
     2881 tagatgccga tgtttttagc acctagtgat gctagttttg ctcgaaagtt ttcgacacct
     2941 tcgttcatat tagacatggt tttgtcttcc acgtcaagcc aatagtaact agggctgtaa
     3001 ggagaggcag cattgtagaa aacttcggca gccttttcca tttcttggac actttttcca
     3061 gctacataag cgtagacagc aactgggaca ttccgctttt gaagttcagt gatatgactc
     3121 ttataggcct tgtctattcc attgataaat gaagcatcat tttcttttgt tgtttgagca
     3181 ccactgtgaa cacgaacaat agcacctgaa atattttgtg agagggcatc gtagttgatt
     3241 tcctcaggac gctgccagcc agagaggtca ataatcggtt tgtctaagtg tttcaaagcc
     3301 tgtgcttcaa tctgtgctat attggatttt gttttaaacg attggctgtc attaagtggg
     3361 cgattgatga ttaaaatgaa catcataatc ccaaaaaaac taaataaaat aagtggatga
     3421 atttgttttc tcatatctta taattctacc ctaaaaatca aaaaaaatca aaaaaatggg
     3481 ttaaggaaga gactttagag cattttttca ttcaagagtg cggaatgatt tgaaatatgg
     3541 tataataaaa gggaatttct acagaaaaga gaagattatg tcaaattttg ccattatttt
     3601 agcagcgggt aaagggactc gcatgaaatc tgatttgcca aaagttttgc acaaggttgc
     3661 gggtatttct atgttggaac atgttttccg tagtgtggga gctatccaac ctgaaaagac
     3721 agtaacagtt gtaggacaca aggcagaatt ggttgaggag gtcttggctg aacagacaga
     3781 atttgtgact caatctgaac agttgggaac tggtcatgca gttatgatga cagagcctat
     3841 cttagaaggt ttgtcaggac acaccttggt cattgcagga gatactcctt taatcactgg
     3901 tgaaagcttg aaaaacttga ttgatttcca tatcaatcat aaaaatgtgg ccactatctt
     3961 gactgctgaa acggataatc cttttggcta tggacgaatt gttcgtaatg acaacgctga
     4021 ggttcttcgt attgttgagc agaaggatgc tacagatttt gaaaagcaaa tcaaggaaat
     4081 caacactgga acatacgtct ttgacaacga gcgtttgttt gaggctttga aaaatatcaa
     4141 taccaataac gctcaaggcg aatactatat tacagacgtc attggtattt tccgtgaaac
     4201 tggtgaaaaa gttggcgctt atactttgaa agattttgat gaaagtcttg gggtaaatga
     4261 ccgtgtggcg cttgcgacag ctgagtcagt tatgcgtcgt cgcatcaatc ataaacacat
     4321 ggtcaacggt gttagctttg tcaatccaga agcaacttat atcgatattg atgttgagat
     4381 tgctccggaa gttcaaatcg aagccaatgt tatcttgaaa gggcaaacga aaattggtgc
     4441 tgagactgtt ttgacaaacg gtacttatgt agtggacagc actatcggag caggagcggt
     4501 cattaccaat tctatgattg aggaaagtag tgttgcagac ggtgtgacag tcggtcctta
     4561 tgctcacatt cgtccaaatt caagtctggg tgcccaagtt catattggta actttgttga
     4621 ggtgaaagga tcttcaatcg gtgagaatac caaggctggt catttgactt atatcggaaa
     4681 ctgtgaagtg ggaagcaacg ttaatttcgg tgctggaact attacagtca actatgacgg
     4741 caaaaacaaa tacaagacag tcattggaga caatgtcttt gttggttcaa attcaaccat
     4801 tattgcacca gtagaacttg gtgacaattc cctcgttggt gctggttcaa ctattactaa
     4861 agacgtgcca gcagatgcta ttgctattgg tcgcggtcgt cagatcaata aagacgaata
     4921 tgcaacacgt cttcctcatc atcctaagaa ccagtaggag cctatcatgg agtttgaaga
     4981 aaaaacgctt agccgaaaag aaatctatca aggaccaata tttaaactgg tccaagatca
     5041 ggttgaatta ccagaaggca agggaactgc ccgacgggat ttgattttcc acaatggggc
     5101 tgtctgtgtt ttagcagtaa cggatgaaca aaaacttatc ttggtcaagc agtaccgcaa
     5161 agctatcgag gctgtctctt acgaaattcc agccggaaaa ttggaagtag gagaaaacac
     5221 agcccctgtg gcagctgccc ttcgtgaatt agaggaagaa acagcctata cagggaaatt
     5281 agaactcttg tacgattttt attcagctat tggcttttgt aatgagaagt taaaactata
     5341 tttagcaagc gatttgacaa aagtggaaaa tccgcgtccg caggatgagg atgaaacctt
     5401 ggaagtcctt gaagtgagct tagaagaagc gaaagaatta atccaatcag gtcatatctg
     5461 tgatgccaag acaattatgg ctgttcagta ttgggagttg cagaaaaaat agaggaggtc
     5521 agtatgggta aatctttatt aacggatgaa atgattgaaa gagctaatag aggcgaaaaa
     5581 atttcaggtc ctcctttgct agatgataat gaggaaacta agattttacc aacctcttct
     5641 tcccgttttg gttatgccaa tcctaaggat catggtttta gccaggaaac cttgaagatt
     5701 caggtcgaac catctattca taaaagccgt cgtattgaaa ataccaagag aaatgtcttc
     5761 aattctaagt tgaataaaat cttatttgcg gtcatctttc tcttgatttt gcttgtttta
     5821 gcaatgaaac ttttgtaata gaaaaggaat tgaaatgaaa ataggaatta ttgctgctat
     5881 gccagaagaa ctggcttatc tggtccagca tttagataat acccaggagc aagttgtttt
     5941 ggggaatacc tatcatacag gaaccattgc ttctcatgaa gtcgttcttg tagaaagtgg
     6001 aattggtaag gtcatgtctg ctatgagtgt ggcgattttg gctgatcatt tccaggtgga
     6061 tgcccttatt aatacgggtt cagctggggc agtagcagaa ggtatcgctg ttggggatgt
     6121 cgtgattgct gacaaattag cctatcatga cgtagatgtc acagcttttg gctatgctta
     6181 tggacaaatg gcgcaacaac cgctttattt cgaatcagac aaaacctttg ttgctcaaat
     6241 ccaagagagt ttatctcaat tggaccaaaa ctggcatctt ggtttgattg ctacaggaga
     6301 tagttttgtt gcaggaaatg acaagataga agcgattaag tcccatttcc cagaagtttt
     6361 agccgtggag atggaggggg cagctattgc tcaagcagcg cataccctca atctcccagt
     6421 cttagtcatc cgagctatga gtgacaatgc caaccatgaa gcaaacatct tttttgatga
     6481 gtttattatc gaagctggac gtcgctctgc ccaagtcttg ttggcctttt tgaaggcttt
     6541 agattaagcg gaaatttgac agtttttcta gcttatgata agatttaagt aaagaaaagc
     6601 tagaaaacgt ttcagaggat attatgagta ttgaaatgac cgtcagtgag attgcagagg
     6661 tcttaggatt atctcgccaa gcaatcaata accgtgtcaa agaattacca gaagaagaca
     6721 cagataaaaa tgacaaaggg gtaacagttg ttaccagaag tggcttgatt aagctagaag
     6781 aaatctataa aaaaacgatt tttgaagatg aacctgtcag tgaagatgtc aaacaacgtg
     6841 aactgatgga gattctagtg gatgagaaga atgcagaaat tcttcgtctt tatgaacaat
     6901 taaaagccaa ggatcgtcag ttatcagaaa aagacgagca gatgcgtatc aaagaccgtc
     6961 agattgctga gaaagacaaa caattagatc agcaacaaca attgaccctt caagccatga
     7021 aggatcaaga aaatcttaag ctagagctgg accaagcaaa agaagaagtc caatccacta
     7081 aaaaaggctt ttttgctcgt ttatttggag gataatcaag gagctgttta ggttaaatgc
     7141 taacctgatg gcttcttttg tttgtgaata gtatagttga ttagaacaga gacagtagag
     7201 gagaggtaca gaatggaacg attagaagat tacattgctt ttgatttaga atttaatcag
     7261 cacgaaggac aaacacactt gattcaagta tcggcagtgc gttttagaga tggtcgggaa
     7321 atcgatgcct atgattccta tgttcatacc agcgtccctc taaaaagctt tatcaatggt
     7381 ttgaccggga ttacagctga gaccttaaaa gatgctcctc cagttgagaa agtcttagaa
     7441 gaattccaag agtttgtggg ttctttgctg atgataggct acaatgctgc taaaagtgat
     7501 ttacctattt tagcagagca tggtttagac tatagccaac agtacaaggt ggatttgtat
     7561 gatgaagctt ttgaacgtcg gagttcagat ttacatggta ttgccaatct caaattgcaa
     7621 actgttgcct catttcttgg atttcaaggt cagtctcata atagtttaga ggatgctcgg
     7681 atgacggcgc gtgtttacga atccttctta gagtcggatc aagctaggga attgttagag
     7741 acagaaagta gcttatcaaa caatcctttt ggtggcttgg acttgtctca attatttgac
     7801 taggagtgcc tatgaaacct gaaaaaccta aaaaattggg tcttaaacag atttacctca
     7861 atcttgataa aatcctcttt ctatttttct tgatttttat gatagtggag tatttgtggg
     7921 taccattcaa ttcatggttg gctagcttct tattagatca gacaggttat ctttttattt
     7981 cctataacaa tgtcttagcc atccttactc attctccatt gattagtcta gcttttttag
     8041 ccttgattgt aattaacctt ctggttgctt attttcaaat aggactcctc tttattggtg
     8101 ctcgtcatct cctctataat gaaaagcgaa ggctaattga gtatatccgc aaggttttcc
     8161 atgaaagttt tggatttatg aaaaagctaa cttgcgctaa agccttgttt atctttttct
     8221 atatagctat gctgtttcct tttatacgga aaatgctgaa gatttattat cttaataaaa
     8281 tcgtcattcc agagtttatc caagcttatt tagaagatag atattggatg tggtggctga
     8341 gcatcctact tctatctctt atctttctct atgtctctgt cagattgatg tttgcccttc
     8401 cgaagattgt atatgatcag ctgactgttc gagaagcagt gatgtttagc ttggagaaaa
     8461 ccaagaagag agttactttt tatgcttgga atttatttta catcttgctc aaagcacatt
     8521 tattatttta tcttcctttg atccctttat tattggctca aactttggta gatgatatca
     8581 ctcagagaga gtctctgatt cttggtattt tgaattttgt cgtgattaaa aatctctatt
     8641 atatggctct gacttatttt ttggttaaat ttgtttcatt tttgacagga aaggagctgg
     8701 atatgcttcc taggagagaa aaagatcaca tcgtgcgatg gggtgtcatg acttgtgcca
     8761 gtcttttctt tgccttagaa ggttatattt atctggaggc tcccatggtt catctacctc
     8821 aacttatttc tcaccgaggg gtttccaatg caaatgggat tcaaaataca gtagagtcct
     8881 tggaaactac agcacaactc aaaccagact tggtggagac ggatgtgcag gaaacaaaag
     8941 atgggcagtt tgtcatgatg catgatgcta acttgaaaaa tctagcaggt atcaataaaa
     9001 gtcctcaaga cttaaacttg gaggagctta aagggattga tatttttgaa aatggctacc
     9061 agactaaaat ttcaagcttt gaagattatc tcagtcgagc caacgaactt ggtcaaaaat
     9121 tactaattga aattaaaacc agtaaaaaag atagtccaga catgatgaac cgctttttag
     9181 cccgttatgc tgcaaagctc aagatttatg gacatcaaat ccagtcttta gactaccatg
     9241 ttgtcgaaaa agtaagacag tatgatgccg aactgccagt ttatttcatc atgccctaca
     9301 attctgtctt tcctaaaaca agagcgacag gatatactat ggagtactca accttggatg
     9361 aatattttgt aagcaaacta tggacaacgg atcagaaact ttatgtctgg actgtcaatg
     9421 attcagaagc tatcagcaaa tctcttcact taggagtaga tggagtgatt acagatgatt
     9481 tggaaaaagt tcagcgggaa atagaagtag cccaagaaga cccagaatat acggatttgc
     9541 tcttgaaaaa agcattggaa ttctttgaat tttagtaata aaaaagagga acggttgttc
     9601 ctcccatgat aggtaagtat tcttgtgaat gcttgctttt ttgtggttgc aatccgttta
     9661 cgagaattgt ttgtattgtt cttgtttcaa tttactttat agtgctttga agttggaatg
     9721 ctacactata acttctaaaa tatagtgaaa tgaaccaaaa atagtacaca atgtggtata
     9781 atcttcttat ggcatattca atagattttc gtaaaaaagt t
//
LOCUS       DBEJJE010000063         9639 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEJJE010000063 DBEJJE010000000
VERSION     DBEJJE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.63"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..220
                     /locus_tag="ACL3F5_001845"
     CDS             <1..220
                     /locus_tag="ACL3F5_001845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGR0515601.1"
                     /translation="LYYRLPIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDNLFEK
                     GKNEIKDSIGTNSVLNKKNYFTKNQKII"
     gene            249..461
                     /locus_tag="ACL3F5_001846"
     CDS             249..461
                     /locus_tag="ACL3F5_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515602.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            519..1160
                     /locus_tag="ACL3F5_001847"
     CDS             519..1160
                     /locus_tag="ACL3F5_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR0515603.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERVELI
                     KEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISKIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            1173..2648
                     /gene="galT"
                     /locus_tag="ACL3F5_001848"
     CDS             1173..2648
                     /gene="galT"
                     /locus_tag="ACL3F5_001848"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0515604.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2661..3671
                     /gene="galE"
                     /locus_tag="ACL3F5_001849"
     CDS             2661..3671
                     /gene="galE"
                     /locus_tag="ACL3F5_001849"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0515605.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3851..4510
                     /locus_tag="ACL3F5_001850"
     CDS             3851..4510
                     /locus_tag="ACL3F5_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0515606.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            4535..5602
                     /locus_tag="ACL3F5_001851"
     CDS             4535..5602
                     /locus_tag="ACL3F5_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0515607.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5706..6716
                     /locus_tag="ACL3F5_001852"
     CDS             5706..6716
                     /locus_tag="ACL3F5_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515608.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGELFTFLGPSGCGKSTTL
                     RALVGFLDPLSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARTLVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6728..8419
                     /locus_tag="ACL3F5_001853"
     CDS             6728..8419
                     /locus_tag="ACL3F5_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515609.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            8422..9132
                     /locus_tag="ACL3F5_001854"
     CDS             8422..9132
                     /locus_tag="ACL3F5_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0515610.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            9228..9596
                     /locus_tag="ACL3F5_001855"
     CDS             9228..9596
                     /locus_tag="ACL3F5_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515611.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
BASE COUNT         3329 a         1268 c         1854 g         3188 t
ORIGIN      
        1 actatattat cgcttaccaa tatttgctaa actttcagaa aaaaagttgg agtatatgat
       61 gctaggtgac tgcgtcatgt tagtaaacga aatggaaata actgatcata gagtagataa
      121 cttatttgaa aaagggaaaa atgagataaa agattcaatt ggtacaaata gtgttttaaa
      181 taaaaaaaat tattttacaa aaaatcagaa aattatctaa tcaaccgagt gggtactgga
      241 taggttcgtt ggatgagaga tttttagacc atgctattat taatcaaata gatgttacta
      301 gtgaacaaat tgttttaatg agcgatggct tttatgaatt ctatcaaaat aatcaaaata
      361 aaacttttga agagttaatt aagatgagat ttaattcttc tgctattgat ccaatctatg
      421 gaaagaagga tgatgcaagt attctagtca ttgatgtttg atatattgtt taaaatatta
      481 attgttacta ttgaactttg ttaagaagag gtacctaaat gttaaggtta tatttagaaa
      541 atgaaattat agaattatca aataatttag agaccatttg ggtatctgtg cttgataaat
      601 atgagaagtt atttgaatat ttatcaaatg aagaacgagt agaattgatt aaagaagatt
      661 taatcataaa tgagtcagtt ctaaatattg ataaaaaagg atatgagtta atttgtttac
      721 aacatcctgt ttcatatgac ttaagaagaa ttattagtgt aataaaaata tcaactgaca
      781 ttgaacgtat tggggataga attgttgaaa ttttaaaaaa tctacagatt cttcaaaata
      841 atgaaatttt gaagaaaatt atttcaaaaa taaaaatact tcatgaagtt atcggactgc
      901 atatgaatag ggctatatct tgttatagag aggaacaatc tggatgttta gatatggttg
      961 ttatacaaaa acagaatgag atagaagagc ttagtataaa tatggaaaag aaaataatga
     1021 attacatatt tgaagatgat gggaacgttt ctgaagtaat tagtgcttta gatattattc
     1081 atcaccttga taaaattgct catactacgc aagcaattta taaatggata atgtatagaa
     1141 aatatgggaa cataaattag aaagaaaaat atatgaaaac aattattgat aattttgttg
     1201 atagagtaat tgaatacgga atgtataatg aaattgacaa aatatatgtg aaaaatagag
     1261 tactagcgtt aataggtgag gagggaattg atcgcatttc cgatgaaaat gacctgaaac
     1321 aaataaaaga ttacttagtg gaaatcgcct taaaaaacgg taaaattaaa gatttaatcg
     1381 aggaaaagga atgtttagga gcagagttaa tgaatttcat agttccttta cctagtcgat
     1441 taaatgatat tttttggagt tcatatgata tatcacctca agaagcagtt gaagagtttt
     1501 ataagttaag taaagatagt gattatatta aaacttctgc tattgctaag aatattgagt
     1561 ttcgagcatc aactaaatac ggagagctag agattacgat aaatttgtca aaacccgaaa
     1621 aagatccaaa aacaattgct gctgaaaaat tagtaaaagc aactaattat cccaaatgtt
     1681 tactatgtat ggaaaatgaa ggatatcagg ggcgaataaa ttatccagca cgttcgaatc
     1741 atagaattat tcggttgaaa cttggtgacg aagtatgggg attccagtat tctccctact
     1801 catactttaa tgagcatgcg atatttttga atagtcaaca tgtaccaatg gctattacct
     1861 ctaaaacatt tgaacaatta ttggagattg ttgatatttt gccaggatat tttgctggtt
     1921 caaattctga tcttcctatc tcaggaggct ccattcttag tcataaccac taccagggag
     1981 ggaaacatat tttcccaatg gaaaaagcaa aatttgagag tgaattttgt tttaaagact
     2041 ttgaggatgt taatgctggt attgtaaaat ggccaatgtc agtaattagg ttacaaagtg
     2101 aaaataaaaa tcgcttgtta gatttagcta ctaaaattct aaataagtgg agagaatatt
     2161 cagatttaga agtagacatc attgctatga ctgaagatgt cccacaccat acggtgactc
     2221 ctattgctcg taaagtggac gggagatacg aattagatat tgttctaaga gataatcata
     2281 ctactgaaca atacccagat ggtgttttcc atcctcatca agatgtacaa catattaaaa
     2341 aggaaaatat cgggttaatc gaagtgatgg gacttgcgat attaccacct cgtttgaaac
     2401 cagagttaga agaagttgga aaatatcttt taggagagga taatgcaatt gcggattatc
     2461 atttagaatg ggccgaccaa ttgaaagaaa aatatcctcg cattaataaa gaagaggtta
     2521 atagcgtagt tcaacacgaa gcaggacaag tgtttgcgag agttctggaa gatgcaggag
     2581 tttataagaa tacaccgtct gggcatgaag cgtttatgag atttgttaag tcggttggaa
     2641 ttaattagga ggaaacccag atggcaatat tggtaacagg cggagctggt tatattggta
     2701 gccataccgt agtagaatta ctaaatttag gaaaggaagt tatcattgtc gacaaccttt
     2761 cgaactctag caaattggtg ctagaccgta ttgaagcaat tacaggaata cgtcccgtgt
     2821 tttacgaatt agatgtttgt gataaacaag cattgagaaa ggtatttgaa caagaatcga
     2881 ttgatgctgc aattcatttt gcaggttata aagctgtcgg agaatccgtg caaaagcctg
     2941 tgatgtacta caaaaataat attatgagta cattggcact tgttgaagtg atgtcagaat
     3001 ttaatgttaa aaagattgtc ttttcttcaa gtgcgactgt atatggaatt aacaatcagt
     3061 cacctctaat tgagacgatg caaacaagtg cgacaaatcc ttatgggtat acgaaagtga
     3121 tgcttgagca aattttaaaa gatgttcatg tggcagattc agaatggagt attgcgttgc
     3181 ttcgttattt caatccaatt ggtgctcatg agtctggttt gattggggaa gatccctcag
     3241 gaattcctaa caacttgatg ccttatattg cacaagtagc ggtaggtaag ctatcagagc
     3301 taagtgtgtt cggaaatgat tatgatacgc ttgatggtac tggtgtgcgt gattatatcc
     3361 atgtagtaga tttagcaata ggacatataa aagctttaga aaaagtatct gaaaaaacag
     3421 atgtttatat ctataaccta ggctcgggag aaggcactag tgtattacaa cttgtaaata
     3481 catttgaaag tgttaataag atccctattc cttataaaat agttccaaga cgttcaggag
     3541 acgttgcaac ttgttatgca aatgcagaca aagcatataa ggaattaaat tggaggacaa
     3601 caaaatcgat tgaagacatg tgtagagata catggaattg gcaatcaaaa aatcccaatg
     3661 gctataattg atgatactgt ctatatgagt gctgtatttt gaaaaaatta cttaaccttt
     3721 taatgaaatg catatttaat gaaagataaa tttaaaaaaa tgtttgcaag tgcttgacaa
     3781 aggaaacggt ttcattgtat aatgtaaaca tgatgacacc gatgtcaaat ataaaaaaga
     3841 aggtctttat atgaaaaact taacaaaaat taagttcaaa gagaatgggg aatttaatca
     3901 tttccctggg aatacagttg tagcaaatct ttatactaaa caagatttga tggaagttgt
     3961 tgatattatt caatcacgtt atagagaatt accatttatc gataagttta ctttaactcc
     4021 aaggaattct attcacatga ctgtaattga attgttgtgc catgaaaatc gtgaaacgga
     4081 gttttggagc agtaatcttc ctctagatac acctttacag gaaatacatg attactttgc
     4141 taaacaactt gaaatttttc cattgttgga tgaagaaatt catatgcgta taactgaaat
     4201 gggaaaacaa aacatactag ttgaacctgc agatgaagct tctgcaaaga gattagaaga
     4261 aattcgtact tatgtctcag aaaaagcagg tgtttgtttc cctaatcatg atagatatca
     4321 attccatatt tcaattgggt atcttcggat tcctctaacc gaagaggagg aagaagagtt
     4381 tactaaagtc agagcagaat taactgaaat tttattagag aagattccaa ctattactgt
     4441 aaaccgtatt gactatactg tatttgaaga tatgagacaa tttgttccat atcacgaaaa
     4501 atttaaataa aataataaaa aaggagaact tatcatgaaa aaaatgaaag tttggtctac
     4561 tgtacttgca acgggagttg ctcttactac acttgctgct tgctctggag gttcaaattc
     4621 tacgactgct tcttcatctg aagaaaaagc tgataaaagt caagaattag ttatctattc
     4681 gaactcagtc tcaaatggtc gtggtgattg gttaactgct aaagcaaaag aagctggttt
     4741 taatataaaa atggttgata tcgctggcgc tcaattagca gaccgtgtta ttgctgagaa
     4801 gaataatgca gttgcagata tggtatttgg aattggtgct gttgactcaa ataaaattag
     4861 agatcaaaaa ttactagtac agtacaagcc taaatggtta gataaaattg atcaatcttt
     4921 atcagataaa gataattatt ataatcctgt gattgttcaa ccattagttt taattggggc
     4981 gcctgatgta aaagaaatgc ctaaagattg gactgaatta ggtagtaagt ataaaggtaa
     5041 atattcaatt tatggtcttc aaggtggtac aggacgggca attctagcaa gtatcttagt
     5101 tcgttacctt gatgaaaaag gagatttagg cgtatcagaa aaaggatggg aagttgcaaa
     5161 agaatacttt gcaaatgcct atactcttca aaaaggtgaa agctcagttg ttaaagcgtt
     5221 agataaagaa agcccaattc aatacggtat gatctggggt tctggagcgt taattggaca
     5281 aaaagaacaa aatgttgaat tcaaagttat gactcctgag attggtgtac catttgtaac
     5341 tgaacaaact atggttttaa gcactagtaa aaaacaagcg ttagctaaag aatttattga
     5401 ttggtttggt caatcagaaa ttcaagtaga gtacagtaaa aactttggct ctatccctgc
     5461 caataaagat gccctaaaag agttacctga agatacgaaa aaatttgttg atcaagtgaa
     5521 accacaaaat attgactggg aagctgttgg aaagcatttg gatgaatggg tagaaaaagc
     5581 tgaattagaa tacgtaaaat aagaaataag agttattttt tatgtccaag tctctctatt
     5641 atttctaaat ttaaggaaga aataaagaga ggcttttggt tttagtaata gagggagtta
     5701 gtgagatgat taaatttgat aatattcaaa ttaaatatgg tgattttgtt gcaattgata
     5761 atctgaattt agatatacat gaaggggaac tctttacatt tcttgggcct tcaggatgtg
     5821 gtaaatcaac tactttgaga gcattggtag gttttttaga tccattatca ggaagtattg
     5881 aagttaatgg aacagatgtc actcatttgg aacctgaaaa gcgtggaatt ggtattgtat
     5941 ttcaatctta tgcgctattt ccaactatga ctgtttttga taatattgca tttggtttaa
     6001 aagttaagaa ggtagctcca gatgttatta aagctaaagt atcagcagtg gcagcaaaaa
     6061 ttaagatctc tgatcaacag ttacagcgta atgtatcaga attatctggg ggtcaacaac
     6121 aaagggtagc attggctcgt actctggttc ttgaacctaa aattctttgt ctagatgaac
     6181 cattgtcaaa ccttgacgca aaattacgtg tagatttgag aaaagagttg aaaagacttc
     6241 aaaaagagtt aggtattact actttatatg ttactcatga tcaagaggaa gccttgactt
     6301 tatctgatag aattgcagtc tttaacaatg gatacatcga acaggtcggt acaccagtag
     6361 agatttatca taattctcaa actgaatttg tatgtgattt tattggagat attaatgttt
     6421 tgaccgatga aacagtccac gaagtattat tgaaaaatac aagcgttttc ttagaggata
     6481 aaaaaggata cattcgatta gagaaagttc gattcaatcg tgaaactgaa caagatttta
     6541 ttctaaaagg gacaattatt gatgttgagt tttctggagt tacaattcac tatacaataa
     6601 aagtttctga aagtcagatt cttaatgtaa caagtattga tagtcaggct gctattagat
     6661 ctgtcggaga aagtgtggaa ttatttatca caccatcaga cgttctgcaa ttttaaggag
     6721 gtgcagtatg cgtcataaat taaatttaaa agattggctt attcgtttag ggttaatctg
     6781 gttcttagta acatttatta tttatccaaa ctttgatcta gtagtgaatg tatttgtaaa
     6841 aggaggagaa ttttcccttg atgctgtaca tcgtgttcta aaatctcaga gggcacttca
     6901 gagtattatg aacagtttta agttagcatt ttcactcatt attacagtta atgtcgtagg
     6961 tattctttgt gttctattta cagagtactt tgatattaaa ggtgctaaaa ttttaaaatt
     7021 aggttatatg acctctttaa tttatggagg agtggtttta gcgactggat ataaatttgt
     7081 ctatggtcct tatggattga ttacaaaatt tttacaaaat gttatccctt ctttagaccc
     7141 taactggttt attgggtatg gtgcagtctt attcattatg acattttcag gaactgctaa
     7201 tcatacattg tttttaacaa atacaattcg aagcgttgac tatcacacta ttgaggctgc
     7261 tcgaaatatg ggagcaaaac catttactgt tttccgaaaa gtagtgttac caaccttaat
     7321 tccaactcta tttgcactta ctattatggt ttttcttagt ggtttatctg cagtagcagc
     7381 acccatgatt gttggtggta aagaatttca aactataaat ccaatgatta ttacatttgc
     7441 agggatgggg aattctcgtg atttagctgc cttacttgca attattttag gtattgcaac
     7501 tacaattttg cttactatca tgaataagat agaaaaaggt ggaaattata tttctatctc
     7561 taagactaaa gcgcctctta aaaaacaaaa aattgcgtct aagccttgga atatcattgc
     7621 tcacattgta gcatatggat tgttcacagt tttcatgctt ccactaattt ttatagtatt
     7681 atactcattt acagatccag ttgcaattca aacaggtaac ttaacattat caaactttac
     7741 tttagaaaat tatcgcttat tctttagtaa tagtgcggca ttctctccat tcttggtcag
     7801 ctttatttat tctattattg ctgcgacaac agcaacaatt ctcgcagttg tatttgctcg
     7861 tgttgtcaga aaacataaat ctcgttttga tttcttattt gaatatggtg ctctacttcc
     7921 ttggttacta ccaagtacac ttttagcagt aagtttatta tttactttta atcagccaca
     7981 atttcttgtc ttgaatcaga ttttggtagg tagtttggta attctactta ttgcatatat
     8041 agttgtaaaa atcccatttt cttatagaat ggtacgtgct attttattta gtgttgatga
     8101 tgagatggaa gatgcagcaa gaagtatggg tgcttcacct ttttatacta tgatgaaggt
     8161 tatcattcca tttattttac cggttgttct ctctgttatt gctttaaact ttaactcttt
     8221 attaactgac ttcgacttat ctgtattcct ttaccatccc ctagctcaac cattaggtat
     8281 tacgattcga tctgcaggtg atgaaacagc aacatctaat gcacaagctc tggtatttgt
     8341 ttatacaatt gttctgatga ttatttctgg aacggtatta tacttcacac aaagaccggg
     8401 gcgtaaagta aggaaataat catgacagcc actagtcttg ggttatcaaa tattgaaata
     8461 gttgtcagga ttgttttatc agtagtcatt ggtagtataa ttggtttaga gagagggagc
     8521 aaatcccagc ctgcaggcat ccgaacttat agtattgttt gtctagctgc atgtttgatt
     8581 atgatgacga atgaatacgt atcttataaa tttgggacag gagatcctac acgattagga
     8641 gctcaagtta tatcaggtgt gggttttcta ggcgctggaa cgattcttat tacagataaa
     8701 aagaaaatta caggtctgac aactgcagca ggcatttggg cttcggcagg aattggatta
     8761 gctattggag taggttttta tgagggagct cttttagtag ccatttctgt ttggggtgtg
     8821 atatccatgt tccaaccact aaaaaaatat ctgcaaaatc gttctaaaat gattgaattg
     8881 tatatagtgg ttaaatctac agaagcctat aatcgtgtat tggtttattg tgcagaaaat
     8941 ggtatcagaa tgaccgattc aagaacagcg tttggagatg ttaattctga cagaattgaa
     9001 tactttgatg ttccggacaa aaaaatagcg tcatttatta ctctggaatt atcaggtaga
     9061 tttgaacatc ttcgactgat ggaagaaatt gctaatattg taggtgttat ttatgtcgaa
     9121 gaaattagct gaaatttagt aaacaaaggg acagatgttt ttgtcctttt gttttttaga
     9181 tgttttaatc atctaatttt tgagtagatt tttgctcaga ggtttttatg aaagattata
     9241 aaatcaattt tgatttaggt aaaatagaat attttgataa taattgtttg atacaagtat
     9301 acaaatttat ttctttttat gatatttgtg aaatggtgtt tgcctttcat ttacctcctg
     9361 atgagttgat aacaaatgtt atctttaaag aaaaaattaa ctctatgtta aaatgttaca
     9421 ttgacaggct attatatgtt tttataaatc ctacacattt tactgaaaaa gttaatctac
     9481 aattttatgg tagctttttc tcatatgaat ttatttgtcg tgaagttgga aacattctta
     9541 aaaataaagg tgtgaaatgc aatttaaact tttttgaagg ggaagaatat ttgtaaaatt
     9601 aattttgtga atttgtggat cttaaataat ttactaaat
//
LOCUS       DBEJJE010000064         9300 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEJJE010000064 DBEJJE010000000
VERSION     DBEJJE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.64"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL3F5_001856"
     CDS             complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL3F5_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0515612.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL3F5_001857"
     CDS             complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL3F5_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0515613.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3593..4114)
                     /locus_tag="ACL3F5_001858"
     CDS             complement(3593..4114)
                     /locus_tag="ACL3F5_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0515614.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKITGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4072..5178)
                     /locus_tag="ACL3F5_001859"
     CDS             complement(4072..5178)
                     /locus_tag="ACL3F5_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0515615.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGFEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5289..5543)
                     /locus_tag="ACL3F5_001860"
     CDS             complement(5289..5543)
                     /locus_tag="ACL3F5_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515616.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTLTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(5537..5779)
                     /locus_tag="ACL3F5_001861"
     CDS             complement(5537..5779)
                     /locus_tag="ACL3F5_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515617.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     ALNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5901..6745)
                     /locus_tag="ACL3F5_001862"
                     /pseudo
     CDS             complement(5901..6745)
                     /locus_tag="ACL3F5_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            6979..8697
                     /locus_tag="ACL3F5_001863"
     CDS             6979..8697
                     /locus_tag="ACL3F5_001863"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0515618.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQIPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8808..9155
                     /locus_tag="ACL3F5_001864"
     CDS             8808..9155
                     /locus_tag="ACL3F5_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0515619.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
BASE COUNT         2695 a         1921 c         1720 g         2964 t
ORIGIN      
        1 ttgatttcat attactattg tataatgctt tttgatttga gtctagtatt atactcttcg
       61 aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg acttcgtcag
      121 ttctatctac aacctaaaaa cagtgttttg agcagtctgc agctaacttt ctataacaaa
      181 atgaaataag aacaagacaa atcaatcaag acaatcaaat cgatttctaa caatgtttta
      241 gaagtagatg tgtactattc tagtttcaat atattatagt ttgctctttg attttcattg
      301 agtattagtt caatatctaa aaaaagaacc ttgccaagca agattctttt agtgtctaac
      361 ttaaataatt gttcttctgg gaactaaatc gaattaagct tcgatttctg taaccatacc
      421 tgaaccaaca gtacgtccac cctcacggat agagaatgta gtaccttgtt ctacggcgat
      481 tgggtgaatc aactcaacgt cgattgtcac gttatcacca ggcattacca tttcagtacc
      541 tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt gtggacggta
      601 gttgttgaag aatggagtgt gacgtccacc ttcttcttta gtaaggatgt agacttcacc
      661 tttgaattta gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc cacgttcgat
      721 ttcatcacgt tgaacaccac gaagaaggac acctacgtta tctccagcaa gaccttcgtc
      781 aagttgttta cggaacattt caacaccagt aacaactgct ttttgagttt cttctttgat
      841 accaacgatt tcgatttcgt cgttgacttt aacgatacca cggtcgatac gtcctgaagc
      901 aactgtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca atggtttgtc
      961 agtgtcacgt tctggttctg ggatatactc atcaactgtg ttcatcaatt ccataacgat
     1021 gtcttcgtat ttagagtcac cttcaagagc tttaagtgct gaaccttgga taactggaag
     1081 atcgtcacct gggaagtcgt attctgacaa taggtcacgg atttccattt caaccaattc
     1141 aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa ggtgtttaac
     1201 accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc cgtcagttga
     1261 agctactaca aggatagctc cgtccatttg agcagcacca gtgatcatgt ttttaacgta
     1321 gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac
     1381 gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct ggagcagcat cgatagacgc
     1441 atagtcttta ggttggttaa ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc
     1501 tgcagttagg gtagttttac cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg
     1561 tttactacga tcgtattttt cttttgccat ttgagtaaaa gcctccaata aaatatattt
     1621 tatagataga cagtaggcaa tacagtctaa ctttccttac tattttatca aatttcagct
     1681 aaattgcaag tgttttacaa cgtttttgtg aattattctt ggtaaaaatt taactaatta
     1741 atagaaagta ctaaatagac ttatccttca aggagttttc agcattatcc atccactcac
     1801 ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga atagggcaaa
     1861 tcgttcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct
     1921 agtttcaatc tactatacaa cctcaaaact gtgttttgaa caacctgcgg ctagcttctt
     1981 agtttgccct ttgattttca ttgagtataa aattgcagat aaaacgataa caatcatagg
     2041 actcagcaga gtcaatgtag gtcgaagaat agccccccta atcgcttatt ttatagcaaa
     2101 atgaaataga aactgaacat tttgttgagg aaggtaaatc aattcctcac aatgtttgag
     2161 aaagaaggga ggactattcc aacttcaatc cactataaag cagacttaca agatagggaa
     2221 cccatctccg ataatatata gtagaatgaa aactgcacaa tttgattgga gaattcaaac
     2281 caatttctca caatgtttta gaaacaaggg tctattattt caactgcaac ctactatagc
     2341 ccattgaagc tggaatagcc cactgagact tctaaaccac tgctgaagag gagtttgttt
     2401 agagtttctt tcatttccct aaaaaatcaa aaagagagaa ccagtctgat cctctcttac
     2461 ttatagatgg tgctcactca aatgttaaag gagctatttc ttagagataa aggaatttga
     2521 atacagctac tgccgcaatt gctgctgcga taggtgctac tactggtacc caagaatacc
     2581 accattttga atcgccttta tgctcaccaa gaactgattt tggaaggaaa gcatgaagga
     2641 gacgtggtcc caagtcacgg gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg
     2701 ttaccaaagc cataacgagg aatccaagtg ccaagtgagc cacagaaagt cctgaagcag
     2761 tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt
     2821 ctattgcctt ttgtttcatg aattgaagca cttcagcacc aaagaagttt ttagtcaaac
     2881 caagagctgc aaagaacaaa acaaatgaac caacaaactc attaatcaaa ccattgacag
     2941 ttgctgcata gcgactttct tttgtaccat ggtcaatact tgaaatagtt gagaaagttc
     3001 ccaagatgtt atttgggttt tcagttttca agtagaatgg acggtatgtt gccacaacta
     3061 aggcttggcc aaagatagcc cccaagactt gcgcgataat gtaaggtacc acttgtgccc
     3121 aagggaaaag accgctaact gcaagcccta gagtgaaagc agggttgatg tgattcccag
     3181 atacgttacc aaacatcaag gctgggatca taacccccat accataacca acagcgatga
     3241 cgatccagcc actttggtga cctttcgtac ctttaagttc aacgttggca actgcaccat
     3301 tcccaagaat gatcaaaatg gcagttccca aaaattcagt ggcatacttc agtgcccatg
     3361 tgaaatccat ttgctagatt ctccttaaaa ttttttagat attccttatt ttatcaattt
     3421 ttaccctatt tagcaactga tttctggaaa tatttttaaa aaaataggat tcatagtttc
     3481 ccagtccaac gtacttgtaa gcgtttttat tcttcacgaa agacctcatt ctcaaaacca
     3541 ggaaaaagcc cacatctgtg atcttttcct tgttcctaga ttctaaaatc tattattttt
     3601 catcttcttt tttcttgaag aatcctaatc ctagaccagc taacaaggtc atgataccag
     3661 cactagccaa ggtagcatta gcttctgtac ctgtgtttgg caattcctct ctcttacctg
     3721 tctcataagt cggaacttct gggtctggat tcactggagt ttcagttttt ggagtacctg
     3781 gttctggagt tggtttatct ggtgttgata aacggtcata ccttaccgtt atttctttat
     3841 cactagagtc tgacgtaact tcttgtgatt caactgttgg aatatctgga tctttgtact
     3901 tgtcaatctt accagatata acctcgtccc agtttcctgt tgtccattca ccgtaggtta
     3961 caactcccgt gatcttgttc tcagtttttg tacggcttaa ggttacaggt tgaacaacat
     4021 cttcttttac attttggttc gtaactttat caacgtaatg aatgatacgc gttatagtct
     4081 tcgtctcagt agaggttgct gttttgggaa ccactgtttc ctcaacattc tcacggtagt
     4141 aatagtcaac tgttgcaccg tcttctggta cgcatttgca ggagttgcta ccaaggtata
     4201 tgttgttttc cttgtgataa ctcggtcttc tttgtcctca gttgttgttt tcccttcaat
     4261 agtttttgat tctgtggtat actcaaaacc tatcgctaaa tcagctttta taacagactc
     4321 tgccaacttc tcttggctac cttctttata gtaattggct gttactgtag cagtggttgg
     4381 cgcttcgctt tctctataaa ctaaggtcac tgttctacct tcacttacaa tattcccagt
     4441 taaacttgca gaatttgtat ctgcttcttt aaaagtataa tattttccgt cagtagtagt
     4501 catgctactg agttttttat ctgtgacatt gtagctggta ccaatcagtt gttttttatt
     4561 ggtaatgtag gttccgtcac tttctttttc tccaattcca gtatcatttt tcaatgatag
     4621 caaacgccct tgttcatcaa catagcgaac tttcacattt tctgagatta gttctgccaa
     4681 ttctgaggtt tttttctttt tcttgatttc ttcggttatt ttccctttct cttcttcggg
     4741 aatatttagt tttggaatga ttttttcaac aacggttcgt gatggttcca cagtatcttg
     4801 gatgactgaa aagtcagcta gaattgggag attatactga acacggtgac tttgagtgtt
     4861 tactcctact ctttcattat tctctgaaaa tacttgtacg gtataagaaa caacatcttt
     4921 tcctaataga acatccccag tagagaaata gccgcctttt cctagtttgc tatctccaga
     4981 gcccacttct ttcctaatct tatcagatag ttttttacca gtcagtacat tcgttcgcac
     5041 aatccctttg tctaccccta caaagtggga gaactttttg aactcttcag aaccagatct
     5101 agcccaacca ttattaaggg catttgcttt tgtatttgta ttctctctca aaagtttggc
     5161 gattagaatt atattcatcg gcacttagag ttgctgctat atctgactct tgaataccaa
     5221 cttccttact accatttcta gcggcagtat atgtgtattt atctgtttct acttctagct
     5281 gattatcctt aacatgatag gtaattttct cctggtataa gagtcttcag tagtttatat
     5341 actctgtcat catctttagc tttagaagca gctgagttta gccaagttag ggtattagga
     5401 gtatctttat cagcctgttt caagacatta ttcaagtcat ttgctagcct attggttatc
     5461 ctcactgtga aagttttctt ccagtctgaa ccacttttat tagacttaga tatgctcatg
     5521 aaatcctggt caacattcaa cacaatatcg ccttgttttt tagcatcttc cgttgcttct
     5581 gcttcaaatt gatcatggag tttttgttgc tctggtgtat agttttttta tttacacgat
     5641 ttaatgcact attttttatt ttagtattaa gaactccatt aatacgattt ttaaactctg
     5701 cttcaaaaaa tcccttaatt tgttggtgcg caagttcaac attcaaacct ttcttataca
     5761 agtcttcatt ctgatacaag tcttcattct gaacgatttc ggctacacgg tgaatggttt
     5821 gatcgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     5881 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     5941 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     6001 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     6061 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     6121 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     6181 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     6241 gaagtccgct caaaacgccg tccgctaatc ttgccataga ctttctcccc tctaggagcc
     6301 cctgcataag gacgatagag gtagcggtcg attcccgttt cgtcaatata taggactggt
     6361 aaatctttta ggttatccaa aatatcaaga aactcagaaa ctttctcagg cttttgttcc
     6421 ctaaaactgg tcgtcttttt taaaatgacc ttaatctgct ttaaaactgc ccatacggag
     6481 ggcaaagcac aatcaaaacg ggccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6541 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6601 tctatgtgtt cttgttcacg tctttctttt cccacgtgaa gagagttctg acgccaacac
     6661 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatgtaatct aatgctcgct
     6721 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagta
     6781 actatatcaa tgttttgtta tgagaagact tacttttttt actgaaattg aatttttcct
     6841 agcctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     6901 cagataaggt tttactaaaa ctaaaaaaaa tgatataatt aaactgatta aatgttttaa
     6961 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7021 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7081 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7141 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7201 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7261 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7321 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7381 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7441 gtttacggtg aagacggtgg acaaatacct ccacacgatg cggacgcttt gactacttat
     7501 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7561 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7621 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     7681 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     7741 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     7801 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     7861 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     7921 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     7981 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8041 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8101 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8161 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8221 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8281 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8341 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8401 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8461 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8521 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8581 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     8641 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     8701 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     8761 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     8821 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     8881 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttg
     8941 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9001 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9061 taccaggttt tattcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9121 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9181 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9241 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
//
LOCUS       DBEJJE010000065         8797 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEJJE010000065 DBEJJE010000000
VERSION     DBEJJE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.65"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..993
                     /locus_tag="ACL3F5_001865"
     CDS             <1..993
                     /locus_tag="ACL3F5_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0515620.1"
                     /translation="MLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKL
                     GERLFQKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQI
                     RMEIENKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILE
                     GAWFIRLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYF
                     PNEQIDTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYL
                     KHNIFRNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            1105..2196
                     /gene="ulaG"
                     /locus_tag="ACL3F5_001866"
     CDS             1105..2196
                     /gene="ulaG"
                     /locus_tag="ACL3F5_001866"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0515621.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            2310..4286
                     /gene="tkt"
                     /locus_tag="ACL3F5_001867"
     CDS             2310..4286
                     /gene="tkt"
                     /locus_tag="ACL3F5_001867"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0515622.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKKL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            4403..4702
                     /gene="yajC"
                     /locus_tag="ACL3F5_001868"
     CDS             4403..4702
                     /gene="yajC"
                     /locus_tag="ACL3F5_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0515623.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            4749..5177
                     /locus_tag="ACL3F5_001869"
     CDS             4749..5177
                     /locus_tag="ACL3F5_001869"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0515624.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            5179..5589
                     /locus_tag="ACL3F5_001870"
     CDS             5179..5589
                     /locus_tag="ACL3F5_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0515625.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            5889..8540
                     /gene="adhE"
                     /locus_tag="ACL3F5_001871"
                     /gene_synonym="adhC"
     CDS             5889..8540
                     /gene="adhE"
                     /locus_tag="ACL3F5_001871"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0515626.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         2795 a         1664 c         1835 g         2503 t
ORIGIN      
        1 atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca gtatcaagaa
       61 agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga gtatcaggtg
      121 tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa
      181 gtttctcttg tagctgttct cctcctctcc tatcgtaagg atttggatat tcatgcagaa
      241 agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta ttttgaatca
      301 caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat gatccactgt
      361 aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct aacaaaacaa
      421 attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga aattttagaa
      481 ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat tcatattgga
      541 ggatttttaa agtatacacc atcgtctcaa aaaaatatga aaaaagttta tctcgtttgt
      601 gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta ttttccaaat
      661 gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga tattgcacaa
      721 gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat tttaagggtt
      781 aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa acacaatata
      841 tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc gtcttatatt
      901 gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat aaataaagaa
      961 atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg aacacaaacc
     1021 tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct caaagataac
     1081 aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag agagtcatgg
     1141 attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga agaagaagtc
     1201 gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg gattaagaca
     1261 ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa
     1321 gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg taagttgcaa
     1381 ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga actagactat
     1441 tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc agcaattctc
     1501 aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg acgaatctgg
     1561 gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga cactatcgaa
     1621 ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt ggtaactctc
     1681 ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt tacagatgaa
     1741 gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac catctatcat
     1801 ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt taaaattgat
     1861 gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat gacatctatc
     1921 gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt tcactatgat
     1981 atctggtcta acttcatggc ttctactaat gagattctag aactttggaa aatgcgaaaa
     2041 gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa gtacacttat
     2101 cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga ttgttttgaa
     2161 caagactcta acattcaatt taaagctttg ctataatata aaaatattct ttggaggtta
     2221 tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat gtgtgattca
     2281 ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat gcaattcgtt
     2341 ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg gttatgggag
     2401 cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca gctcaaccaa
     2461 actggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg ctcctttatg
     2521 ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag agtttccgtc
     2581 aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg attgatgcta
     2641 cgacaggtcc tctagggcaa gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt
     2701 tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat acttacgtta
     2761 tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca tacgcaggtt
     2821 tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac ttggatggtg
     2881 agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac ggttggcata
     2941 ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc gaaacagcaa
     3001 aagcttcagg caagccatct ttaattgaag tgaagacggt tattggatat ggttctccaa
     3061 acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa actgcatcaa
     3121 ctcgccaagc cctcggttgg gactacgaac catttgaaat tccagaacaa gtatatgctg
     3181 atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg actaaattag
     3241 ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc atcatcgacg
     3301 gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat ggtttttctc
     3361 aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa ttaccaacct
     3421 tcctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag acagatggac
     3481 ttcaagacga tgccaatcgc ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa
     3541 tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac ggtggaactt
     3601 tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta caaggacttc
     3661 ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt ccgactcacg
     3721 aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag
     3781 cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag aaaacaccaa
     3841 ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac ttcgacaagg
     3901 ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc atcttgattg
     3961 cgacaggttc agaggttaat cttgctgtct cagctgctaa aaaattggct agtcaaggcg
     4021 aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa gatgcagctt
     4081 acaaggaaga gattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa
     4141 gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt gataccttcg
     4201 gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta gaaaatcttg
     4261 taaaaattgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc tggtttttct
     4321 taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata gtagtcctat
     4381 gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca tgcttgtagg
     4441 tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat
     4501 ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg gactttatgg
     4561 aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag atggagttta
     4621 cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa cagcttcact
     4681 agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta taaaagaaag
     4741 gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt agccctatgg
     4801 ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga gcaacttcct
     4861 cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa cagtatgaga
     4921 ttccttatga caagaacaag acatcacttc agattagtaa ggaagatttt gaagcctttg
     4981 attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg tgtccagtag
     5041 actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct tggtatacag
     5101 gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt
     5161 tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta tcgtgtctat
     5221 ctgactcgtc cacgtttaga gcttttggca gtagttacca ttgttttctg tgctgtactc
     5281 gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt
     5341 tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac cttccaaaat
     5401 ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg tacctttcaa
     5461 tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg
     5521 aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa
     5581 caaaaataaa gcctccttat caaaggaggt attattagaa ttacaaggta agcgcttacc
     5641 tgtaaatccc tttccttcca aatccctctt ccaagcaagt ttgtgaaata aaaaatattt
     5701 gaaataaatt tcacaaactt caaagataaa acctgataag aaaagaaaat gagaaaagtt
     5761 tcacaagagt ttaaaaattc tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata
     5821 atacgttata ataaacttgt gaaaaaatta acaaaggata tcgttccttg aaagctatgg
     5881 aggaaaatat ggctgataaa aaaactgtga caccagagga aaagaaactc gttgctgaaa
     5941 aacacgtaga tgagttggtt caaaaagctc tagttgccct tgaagaaatg cgtaaattgg
     6001 atcaagaaca agttgactac atcgttgcca aagcatcagt agcagctttg gatgcccacg
     6061 gagaattggc tttacatgcc tttgaagaaa caggacgtgg tgtatttgaa gataaagcaa
     6121 ctaagaactt gtttgcttgt gaacacgtgg taaacaacat gcgtcacact aagacagttg
     6181 gcgttatcga agaagatgat gtaacaggat tgaccctgat tgctgaacca gttggtgttg
     6241 tttgtggtat cactccaaca acaaacccaa catcaacagc gatcttcaaa tcattgattt
     6301 cattgaagac acgtaatcca atcgtctttg ccttccatcc atcagctcaa gaatcatcag
     6361 ctcatgcagc tcgtatcgtc cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg
     6421 tacagtggat cactcaacca tctatggaag caactagtgc ccttatgaac cacgaaggta
     6481 ttgcaacaat ccttgcaaca ggtggtaatg ccatggttaa agccgcatac tcatgtggta
     6541 aaccagctct tggggtaggt gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca
     6601 ttcgtcaagc agcacacgat atcgtcatgt ctaaatcatt tgataacggt atggtctgtg
     6661 catctgaaca agcagttatc attgataaag aaatttacga tgaatttgta gcagagttca
     6721 aatcttacca cacttacttt gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct
     6781 tcggcgtcaa agcaaacagc aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg
     6841 gtaaaccagc aacttggatt gcagaacaag caggatttac agttccagaa ggaacaaaca
     6901 ttcttgctgc agaatgtaaa gaagttggcg aaaatgagcc attgactcgt gaaaaattgt
     6961 caccagttat tgcagttttg aaatctgaaa gccgtgaaga tggtattact aaggctcgtc
     7021 aaatggttga atttaacggt cttggacact cagcagctat ccacacagct gacgaagaat
     7081 tgactaaaga atttggtaaa gctgttaaag ctattcgtgt tatctgtaac tcaccttcta
     7141 cttttggtgg tatcggggac gtttacaatg ccttcttgcc atcattgaca cttggatgtg
     7201 gttcttacgg acgcaactca gttggggata acgttagtgc cattaacctc ttgaatatca
     7261 aaaaagtcgg aagacggaga aataacatgc aatggatgaa acttccttca aaaacatact
     7321 ttgaacgtga ttcaattcaa taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg
     7381 ttactgacca tgccatggta gagcttggtt tccttgatcg tatcatcgaa caactggacc
     7441 ttcgtcgcaa taaggttgtt taccaaatct ttgcggatgt agaaccggat ccagatatca
     7501 caactgtaaa ccgtggtact gagattatgc gtgccttcaa accagatacc atcatcgcac
     7561 tcggtggtgg gtctccaatg gatgctgcca aagtaatgtg gctcttctac gagcaaccag
     7621 aagtggactt ccgtgacctt gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt
     7681 tcccattgct tggtaagaag actaaattca tcgcgattcc aactacatct ggtacaggat
     7741 ctgaagtaac accatttgcc gttatctctg ataaagcaaa caaccgtaaa tacccaatcg
     7801 ctgactactc attgacacca actgtggcaa tcgtagatcc tgctttggta ttgacagttc
     7861 caggatttgt tgctgctgat actggtatgg acgtattgac tcacgcgaca gaagcatacg
     7921 tatcacaaat ggctagtgac tacactgatg gtttagcact tcaagccatt aaattggtct
     7981 ttgaaaatct cgaaagctca gttaagaatg cagacttcca ctcacgtgag aaaatgcata
     8041 acgcttcaac aatcgctggt atggcctttg ccaatgcctt cctaggtatt tctcactcaa
     8101 tggcccataa gattggtgcg caattccaca caatccacgg tcgtacaaat gctatcttgc
     8161 ttccatacgt tatccgttac aacggtacac gtccagctaa gacagcaaca tggcctaagt
     8221 acaactacta ccgtgcagat gaaaaatacc aagatatcgc acgcatgctt ggacttccag
     8281 cttctactcc agaagaaggg gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac
     8341 gtattgggat ccaaatgaat tttagagacc aaggaattga cgaaaaagaa tggaaagaac
     8401 attctcgtga attagccttc ctggcttatg aagaccaatg ttcaccagct aacccacgtc
     8461 ttccaatggt agaccatatg caagaaatca tcgaagatgc atactatggc tacaaagaaa
     8521 gaccaggacg ccgtaaataa ttgtttatca gtctagaagc aagacaaaaa ctcaatttga
     8581 gggaaagatc cagtactttt tctatgataa aaggcatcct atcaaggttt ttgaacacct
     8641 gataggatgc ctttttatga tattgaggcc tttttgccct ttttgaaaaa ctagaataga
     8701 aacaaaatat ataatagatt gaaactggaa tagtacactt ctgcttctaa aacattgtta
     8761 gaattcgatt tgactgtcct gatcgatttg tcctgtt
//
LOCUS       DBEJJE010000066         8398 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEJJE010000066 DBEJJE010000000
VERSION     DBEJJE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.66"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(549..857)
                     /locus_tag="ACL3F5_001872"
     CDS             complement(549..857)
                     /locus_tag="ACL3F5_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0515627.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="ACL3F5_001873"
     CDS             complement(854..1162)
                     /locus_tag="ACL3F5_001873"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515628.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="ACL3F5_001874"
     CDS             complement(1167..2462)
                     /locus_tag="ACL3F5_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0515629.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="ACL3F5_001875"
     CDS             complement(2480..3889)
                     /locus_tag="ACL3F5_001875"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0515630.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="ACL3F5_001876"
     CDS             4047..4775
                     /locus_tag="ACL3F5_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0515631.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="ACL3F5_001877"
     CDS             5234..5428
                     /locus_tag="ACL3F5_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0515632.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5550..5716)
                     /locus_tag="ACL3F5_001878"
                     /pseudo
     CDS             complement(5550..5716)
                     /locus_tag="ACL3F5_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5794..7104)
                     /locus_tag="ACL3F5_001879"
     CDS             complement(5794..7104)
                     /locus_tag="ACL3F5_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0515633.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7341..8213
                     /gene="nadC"
                     /locus_tag="ACL3F5_001880"
     CDS             7341..8213
                     /gene="nadC"
                     /locus_tag="ACL3F5_001880"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0515634.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2621 a         1462 c         1588 g         2727 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatag ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactaca tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg aatttttaaa
     5641 gttgaactaa tcatttttac aggatgaggt ttacagcaga gagtttgaag gctttatcaa
     5701 aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt
     5761 ataccaagtc cacccttaag ttagataata aatctaactt aaggaagcta gaaggatgag
     5821 aatccaggtg gtcaagagtc ccaaacttaa gctgatgggg acacccagaa taatttgctt
     5881 tttgaaggca aggccacgtt cctctatatt gggaagtgag agttgaatga gagaaccagc
     5941 tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg ttgtgagtaa
     6001 gtgaatatca atctggggat tttgagcact gatgatagca atgatgggaa agagggctgg
     6061 agctacaacg gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa
     6121 cagaggtaac cagaaatgag gaatggatgt tgtcatgagg tgccctatca gtgtgactaa
     6181 acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga taattgtagc
     6241 ccagggaacc ttagctaaaa tggcttcttg cttccctaat ttgagcctta aggcgaggca
     6301 gaccatgagt attgagacaa agccaatatc aaatgttttt tgataagtag ctatccaggc
     6361 gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat
     6421 catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt caatagtcaa
     6481 ggatgagttt gtttttccct tactatagtg actgtaacag gataataaaa gcaagacgat
     6541 gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc
     6601 ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg ttatcaaatt
     6661 agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt gtttgtccgc
     6721 tttttgacag agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc
     6781 acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg cgttagggta
     6841 ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt tagttattgc
     6901 aaagttataa aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg
     6961 aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat
     7021 agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc
     7081 gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg gaaataggtt
     7141 ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta ttatacacaa
     7201 aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa atgaggtatt
     7261 caggcttgtg atttcctatg gaagttaata gtgattgcct ctaatgctta caagtgatat
     7321 taaaaataga ggacttagtg atgtcaatca tttcaactga tttaacccct tttcaaatag
     7381 atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac agtaccaatg
     7441 ccatttttga tcatcatggc caagccaagg tgtcgctttt tgccaaggaa gctggtgttt
     7501 tagcggggct aaccgttttt aaaagggttt ttaccctatt tgatgccgag gtgaccttcc
     7561 agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg gttttagaaa
     7621 tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat tttttacaac
     7681 atttatcagg gattgcttcg atgacagctg cttatgtaga agccttagac gatgattgca
     7741 ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag aaatatgccg
     7801 tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc atgctaaaag
     7861 acaatcacat tgcggcagta ggtagtgttc aaaaggcaat tgctcaagcg cgtgcctatg
     7921 ctccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc gaagaagctg
     7981 cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag attgaacagg
     8041 ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt gatatgacca
     8101 ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt ttaacccata
     8161 gtgctaagag tcttgatttt tccatgaagg ggttaaccta ccttgatgtc taagttgtaa
     8221 aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt cagatagttt
     8281 aaacgcctct tcaaatatag taaaatgaat caaaaatagt acacaatgtg gtataatctt
     8341 cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacag
//
LOCUS       DBEJJE010000067         6908 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEJJE010000067 DBEJJE010000000
VERSION     DBEJJE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.67"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL3F5_001881"
     CDS             complement(112..387)
                     /locus_tag="ACL3F5_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0515635.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="ACL3F5_001882"
     CDS             complement(494..1333)
                     /locus_tag="ACL3F5_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0515636.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGHILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="ACL3F5_001883"
     CDS             1475..2323
                     /locus_tag="ACL3F5_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0515637.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="ACL3F5_001884"
     CDS             complement(2416..3333)
                     /locus_tag="ACL3F5_001884"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0515638.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3813..3961
                     /locus_tag="ACL3F5_001885"
                     /pseudo
     CDS             3813..3961
                     /locus_tag="ACL3F5_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4181..4474)
                     /gene="rpmA"
                     /locus_tag="ACL3F5_001886"
     CDS             complement(4181..4474)
                     /gene="rpmA"
                     /locus_tag="ACL3F5_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0515639.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4491..4835)
                     /locus_tag="ACL3F5_001887"
     CDS             complement(4491..4835)
                     /locus_tag="ACL3F5_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0515640.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4851..5165)
                     /gene="rplU"
                     /locus_tag="ACL3F5_001888"
     CDS             complement(4851..5165)
                     /gene="rplU"
                     /locus_tag="ACL3F5_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0515641.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5201..5288)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5353..6051)
                     /locus_tag="ACL3F5_001889"
     CDS             complement(5353..6051)
                     /locus_tag="ACL3F5_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0515642.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6453..6752
                     /locus_tag="ACL3F5_001890"
     CDS             6453..6752
                     /locus_tag="ACL3F5_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0515643.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2178 a         1404 c         1143 g         2183 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctaaatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acagcacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatatggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ttttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttattt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgct tatgtatgaa aaagcaatgc aactaactcc tgagaacttt aaattactaa
     3601 ttggtgccga aaaggtagaa tttagaatcg aggtacacct atggctgtaa aatttacaaa
     3661 atgagacaac ttgggcaaga tgtttgaaga atttcctaaa ctccctgatt tgaagcaagt
     3721 cactttccct gatgacaaag aaaaaagcca aaacagcaaa gaaaaactag atgactgctt
     3781 tccaacaact cccatctagt gtgcttcaga ctgggctatt tttctctcca tctgttagct
     3841 tggattctca gacagtttca gctaaagaat atcttttccc ttatcagaag gaacggctca
     3901 aaccattcag acaagtgaag ggacgacaag ccaatatttg aaaccagata gcagttctta
     3961 tagtcaattg aaataaaatc tgaagaaatc gagtaggaaa ctcatatcaa tttttaacag
     4021 tgttctattc cagattcaat ccactataca tattaaaaag tatgggtacc aaaacaaaaa
     4081 aacaggctct ccgaaaactc ggaaagcctt attttaagct gtttctagct tcctcacctt
     4141 tacatttcaa ggttcgggat aaaaggttca atggaccttt ttatttagcg attgggtaaa
     4201 cagaaacttg ttttttatcg cgtcctttac gttcaaagcg tactacgcct tcaactttag
     4261 cgaacaaagt atcgtctcca ccacgaccaa cgtttacacc tggatagatg tgtgtaccac
     4321 gttgacggta aaggattgat ccacctgtta cagtttgtcc gtcagctgct ttagctccaa
     4381 gacgttttgc ttgtgaatca cgtccgtttg atgtagaacc tccacctttt ttgtgggcga
     4441 aaagttgcaa gttgttaaga gtcattttta acataatgtt ttcctccgtg ttagttttct
     4501 gtgataactc tggtttggac gaactcagaa tagttctccg ataagtttgc catacctaag
     4561 aaaaatgatt caaagaataa ctgggtcatt tctctctggt gtgaaggaag atcttttggt
     4621 atttcaacca tcagatagcc accttcatct tcgtttaatt ctaggattgg ttcatagcct
     4681 gcaaatttct caatagaatt gataaagtta atggcaagcg tagaaaccga tgcacacacg
     4741 acatctaagc cgtattcgcc actctcggcg tgtccagtaa tttccgcact cctcagctcg
     4801 ccatcttcgg ctctctcaaa gactgcctgt atcatgtgtt ctccttaaaa ttaagcgttg
     4861 attgcgttga tgacaacttt tgtatatggt tgacggtgac cttgtttacg gtggctacct
     4921 tttttaggtt tgtacttgta agtaaccact ttcttttgtt ttccttgttt ttcaacagtt
     4981 ccaactacag tagctccagc aacaagtgga gttccgacaa cagtgttttc accaccaaca
     5041 agaacaactt cgttaaaagt aacttcttga ccagcttcaa cgttcaattt ttcaacgtaa
     5101 actgcttgac caacttcaac tttaacttgt tttccgccag ttttgataat tgcgtatgtg
     5161 ctcattatgc acctcctatg atttttatgg gtttccccga ttttttgtga agactcgcct
     5221 agcatcgtgg gacgaaccac ttaaacttga ataatcaagc aacgatgttc gtgcggttgc
     5281 acaggatcgt gcatagtcaa ctcttcaagt atagcatatc tcctattttc ttacaagtaa
     5341 taacacctaa aatcaagctt tttcttttac ttttttctgc caagaggcaa aaagcatgct
     5401 gaggtaaaaa acgctcatca taataggaac accaagaatg gtcttttcat gatagaaaat
     5461 cgtcaaatag gctgaaaaga caacgccaag gacaaaacta ctaagcaggc taacaaatat
     5521 gaatccttca cgcaaaaaag gagtgtgctt ggttcggaaa taatctccaa aagccagcat
     5581 ggtccgtttg atattccctg tcataaaagc gttattatag gcaatacccg acacttctcc
     5641 aaaagcagtt gtcaccagtc ccatacagaa ggccaagggc ggcactagat agatattatc
     5701 cacagtttgc ggcacaaaag caataatgat tgataagatt gccaagggaa tcaaggacag
     5761 aataggtttt ttcacaattc tcaatttttc cttataaatc gttaataaaa agactcccat
     5821 cataaacgct agcaaggtga gaaccttgtc cctaacatcc gaaacattat ttttaattaa
     5881 ttctactgaa agaaagacaa catttccagt ttgtccagct acaagggtat tcccgcgaac
     5941 aataaaagtg taagcatcca catatccagc acaaaacgtc aaaaaaagtg ctaacctttt
     6001 agactgacgt gatatttttc ttataggtaa taacctcatt ttacctccca ttgtattttc
     6061 tcttagaaat attgtaccat tttctttcta aaaaatcgta ggctaccatt tagattttac
     6121 tattagcata aaaataataa tagacaacta tttatccaaa aatagataga tgtaacatgt
     6181 ttgcaaacaa agcatacgaa cctttagtaa aatcatttcc atgaaactag aatagagccc
     6241 tcttagcaaa aatcattatt ttaatttatt tctaatcact ccttgacata aataactctc
     6301 accaataaaa gactatgtct taaaaaaatg gtataataaa atcaatactt gggcttgatg
     6361 gctatgctac taataacaat taggagagaa aatcaggcac ttgttaacaa caaggattat
     6421 ccccttgaga tgaaaggaac tttagaaatc ttatgatgaa catgcaaaac atgatgcgtc
     6481 aagcacaaaa acttcaaaaa caaatggaac aaagccaagc tgaacttgct gctatgcaat
     6541 ttgttggcaa atctgctcaa gatcttgtcc aagcgacctt aactggcgat aagaaagttg
     6601 tcagcattga tttcaatcca gctgtcgttg acccagagga ccttgagact ctttctgata
     6661 tgaccgttca agccatcaac tctgctcttg aacaaatcga tgaaactacc aagaaaaaac
     6721 tgggtgcttt cgctgggaaa ttacctttct aaaaacaagg agctagaaca atgcttgtcg
     6781 ataacaaagg ctaagaaagg tgcaaaaatg actctataat atttgtagtg ggtaaatccc
     6841 ctatggatat tatggagctt atttttgtgt agaaaaaaag tcccatatga cctataatga
     6901 aaagcgac
//
LOCUS       DBEJJE010000068         6688 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEJJE010000068 DBEJJE010000000
VERSION     DBEJJE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.68"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..284
                     /locus_tag="ACL3F5_001891"
                     /pseudo
     CDS             1..284
                     /locus_tag="ACL3F5_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            345..1307
                     /locus_tag="ACL3F5_001892"
     CDS             345..1307
                     /locus_tag="ACL3F5_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0515644.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1484..2491
                     /gene="gap"
                     /locus_tag="ACL3F5_001893"
     CDS             1484..2491
                     /gene="gap"
                     /locus_tag="ACL3F5_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0515645.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2559..3434)
                     /locus_tag="ACL3F5_001894"
     CDS             complement(2559..3434)
                     /locus_tag="ACL3F5_001894"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0515646.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3521..5716
                     /gene="pbp2a"
                     /locus_tag="ACL3F5_001895"
     CDS             3521..5716
                     /gene="pbp2a"
                     /locus_tag="ACL3F5_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0515647.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRHFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5769..5921
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001896"
     CDS             5769..5921
                     /gene="rpmG"
                     /locus_tag="ACL3F5_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0515648.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5931..6107
                     /gene="secE"
                     /locus_tag="ACL3F5_001897"
     CDS             5931..6107
                     /gene="secE"
                     /locus_tag="ACL3F5_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0515649.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6162..>6688
                     /gene="nusG"
                     /locus_tag="ACL3F5_001898"
     CDS             6162..>6688
                     /gene="nusG"
                     /locus_tag="ACL3F5_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0515650.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIA"
BASE COUNT         2072 a         1177 c         1442 g         1997 t
ORIGIN      
        1 acgatgacga gcgacttttt tgaagtatgg tttcagaagt ttctcttacc aacattaacc
       61 acaccatcgg ttattattat ggataatgca agattccata gaatggggaa gctagaactt
      121 ttatgcgaaa agtttggcat aaacttttac ctcttcctcc ctactcacct gagtacaatc
      181 ctattgagaa aacatgggct catatcaaaa agcacctcaa aaaggtatta ccaagttgca
      241 atacctttta tgaggctctt ttgtcttgtt cttgtttcaa ttgactatag ttcacggata
      301 cagttgggaa agaagctatt aattatttgg agagtccttt tgggatgaac atgtcaaata
      361 ttactataga tgggcaagaa atggatctga gtcaaacgat gccttcttat gctcaagtag
      421 tgagtcttta tgaggataca agcatctctg ttagtagtaa tgagacggac aaagtgttgg
      481 ctggatccct ctatactgat acaaatgaac agggattaat gattccaagc agtttactaa
      541 aaaattggaa tgaacagaca ggaaaaaatt tgacagctaa tgatcttatt ggcaaatcag
      601 tctcagccag cattgtagaa agtgctgccg aagctagtaa gattgctcaa tttcaaacga
      661 agattgtacg tgtaatcaat gatgaagatg acatggagga cagcaacagt ttcatgctgt
      721 ctcatcaaat ggaaacgatt ttgaaagagg ctggatttac gaaagctgta tcttatttta
      781 tcttggaact caaagatcca tcacagacaa aagtagtaac agaagaatta cagaaaaata
      841 agaagtatac tgtgctttct caacagagag ttcttgatat tgtgattacc tttattcgtg
      901 ttattcaggg attattgatt gtgctttcat cacaagctat tgtggtagca gcggttatga
      961 ttggtatcat tatttacatc aatatcatgc aacgttccaa ggaaataggt gtcatgaaag
     1021 cagttggtta tcagaatcgt ggtgtcaaag gaatttttat ttacgaggct atctggattg
     1081 taggcatcgc cttgctgctg gcatttttgg ttgcacaagg ggtgggaagt ttggcgaatg
     1141 cgattgtaag tcacttttac ccatccatca ctaaggtttt tgaattaaat cttttatctg
     1201 ttttaggaac tctagttttc gctctattac ttggttatgt ctcagcctac ttcccggcgc
     1261 gtaagattag taaaatggat cctgtagaat cgttacgcta tgaataataa gggattcctt
     1321 gatttacagt cttaaaaaga aactcacata gaaaaacaat ggccatactt gcaattcaac
     1381 tcaaatagtt gtataatagg tttgttgaaa ggtgatttgt agtgattcaa gttactcttt
     1441 tcacaataaa aatttcatga ttttcataag gaggaaatca ctaatggtag ttaaagttgg
     1501 tattaacggt ttcggacgta tcggtcgtct tgctttccgt cgtatccaaa acgtagaagg
     1561 tgttgaagtt acacgcatca acgaccttac agatccagtt atgcttgcac acttgttgaa
     1621 atacgacaca actcaaggtc gtttcgacgg tactgttgaa gttaaagaag gtggatttga
     1681 agttaacggt aaattcatca aagtttctgc tgaacgtgat ccagaacaaa tcgactgggc
     1741 tactgacggt gtagaaatcg ttcttgaagc tactggtttc tttgctaaga aagaagcagc
     1801 tgaaaaacac cttaaaggtg gagctaaaaa agttgttatc actgctcctg gtggaaacga
     1861 cgttaaaaca gttgtattca acactaacca cgacgttctt gacggtactg aaacagttat
     1921 ctcaggtgct tcatgtacta caaactgctt ggctccaatg gctaaagctc ttcaagacaa
     1981 ctttggtgtt gttgaaggat tgatgactac tatccacgct tacactggtg accaaatgat
     2041 ccttgacgga ccacaccgtg gtggtgacct tcgccgtgct cgcgctggtg ctgcaaacat
     2101 cgttcctaac tcaactggtg ctgcaaaagc tatcggtctt gtaatcccag aattgaatgg
     2161 taaacttgat ggatctgcac aacgcgttcc aactccaact ggatcagtta ctgaattggt
     2221 agcagttctt gaaaagaacg ttactgttga tgaagtgaac gcagctatga aagcagcttc
     2281 aaacgaatca tacggttaca cagaagatcc aatcgtatct tcagatatcg taggtatgtc
     2341 ttacggttca ttgtttgacg caactcaaac taaagttctt gacgttgacg gtaaacaatt
     2401 ggttaaagtt gtatcatggt acgacaacga aatgtcatac actgcacaac ttgttcgtac
     2461 tcttgaatac ttcgcaaaga ttgctaaata attcttgagt tgatagaaag caaggctttg
     2521 tggtcttgct tttttatatg gaaaaatgga tgacacgatc atccattctt ttttaattct
     2581 ttttcaaatg tatttgaaag ggtagtgaaa gttagcctct ctaaagtaag tgggtgggta
     2641 aaggaaagtc ggaaggcatg aagcataagc cggcttgtct ttgatttact attatagaga
     2701 gggtctccca ggataggaag attatgatgc aaaaggtgca cacgaatctg atgggttcgc
     2761 cctgtcttta gcttgcaatg agccaaggaa gtcttgtttg agaattgctt taatctgctt
     2821 acatgcgttt cagcatattt cccatttttt gcatcaacta ttctttttct acgatcatgg
     2881 cgatcacgtc caattttgtc tctgaaaaca agttcttttc tgttgatatt tccatcaact
     2941 agagcccaat attctctaga aatctctttt ttctccaata agcgattgag aatgggcagg
     3001 ataaaaggat ttttggcaaa gagaactaag ccactggttt ccatgtccag acgatgaacg
     3061 acatagcagg tttggccaac ataggtactg acatggttaa gaagggcaat ttcgtttggt
     3121 tgattaccat gcgttttcat cccctctggt ttgtttacaa taatcaagtg ttgatcttga
     3181 taaacttcct gcactaagtc tgggttgccc caagggatcg tcttttgggg ataatcttcc
     3241 tcgtcaaaag tcaactggca aacatctcca ggatttacga tttcgttcca gcggacttct
     3301 tcttgattta tcaaaatatg tttcttgatt ctcaaaaaat gacggatttt tctagggatg
     3361 aggagttgtt cctcaagtaa ttgctttacc gtcatttgag gtagagaggc gggtaatgta
     3421 aatgtgaatt gcatacagat attgtaacaa aaaaagccct atttggatag gaaatagcta
     3481 aattcttgtc ttcctatgat gaagatgata aaataaacgc atgaaattag ataaattatt
     3541 tgagaaattt ctttctcttt ttaaaaaaga aacaagtgaa ctagaggact ctgattctac
     3601 tatcttacgt cgctctcgta gtgatcgaaa aaaattagcc caagtaggtc cgattcgaaa
     3661 attctggcgt cgttatcatc taacaaagat tatccttata ctaggtttga gtgcaggctt
     3721 gctagttgga atctatttgt ttgctgtagc caagtcgacc aatgtcaatg atttgcaaaa
     3781 tgccttgaaa actcggactc ttatttttga ccgtgaagaa aaagaggctg gtgccttgtc
     3841 tggtcaaaag ggaacctatg ttgagctgac tgacatcagt aaaaacttgc agaatgctgt
     3901 tattgcgaca gaagaccgtt ctttctataa aaatgacggg attaactatg gccgtttctt
     3961 cttggctatt gtcactgctg gacgttcagg tggtggctct accattaccc aacagctggc
     4021 taaaaacgcc tatttatcgc aggatcaaac tgttgagaga aaagcgaaag aatttttcct
     4081 tgccttagaa ttaagcaaaa aatatagtaa ggagcaaatt ctaaccatgt accttaacaa
     4141 cgcttatttt ggaaatggtg tgtggggtgt agaagatgcg agtaagaaat actttggagt
     4201 ttctgcatca gaagtgagtc tggatcaagc tgcgactctg gcagggatgc tcaaggggcc
     4261 ggaactgtat aatcccttga attccgtaga agattctact aatcggcgcg atactgtctt
     4321 gcagaatatg gttgcagcag gatatattga taaaaaccaa gaaaccgaag ctgctgaagt
     4381 tgatatgact tcgcaattgc acgataagta tgaaggaaaa atctcagatt accgttaccc
     4441 ctcttatttt gatgcggtgg ttaatgaagc tgtttccaag tataatctaa cagaggaaga
     4501 gattgtcaat aatggctacc gcatttacac agagctggac caaaactacc aagcaaatat
     4561 gcagattgtt tatgaaaaca catcgctatt tccgagggca gaggatggaa cgtttgctca
     4621 atcaggaagt gtagctctcg aaccgaaaac agggggagtt cgtggagttg tcggtcaagt
     4681 tgctgacaat gataaaactg gattccggca tttcaactat gcaacccaat caaagcgtag
     4741 tcctggttct acaattaagc ctttagttgt ttatacacca gcagttgaag caggctgggc
     4801 tttgaataag cagttggata accataccat gcagtatgat agctataagg ttgataacta
     4861 tgcagggatc aaaacaagtc gagaagttcc tatgtatcaa tccttggcag aatcgcttaa
     4921 tctacctgct gttgccactg ttaatgattt gggtgttgac aaggcttttg aggcaggcga
     4981 aaaattcgga ctcaacatgg aaaaggtcga ccgtgttctt ggtgtcgcct tgggaagcgg
     5041 tgttgaaacc aaccctcttc aaatggctca agcatacgct gcctttgcaa atgaaggttt
     5101 aatgcctgaa gctcatttta ttagtagaat tgaaaatgct agtggacaag ttattgcgag
     5161 tcataaaaat tcacaaaaac gggtgattga taagtctgta gctgacaaga tgaccagtat
     5221 gatgttgggg actttcacca acggtaccgg tattagttca tcgcctgcag actatgtcat
     5281 ggcagggaaa actggaacaa ctgaagcagt tttcaatccg gagtacacaa gtgaccagtg
     5341 ggtaattggt tatactccgg atgtagtgat tagccactgg cttggctttc cgaccactga
     5401 tgaaaatcac tatctagctg gctctacttc aaacggtgca gctcatgtct ttagaaacat
     5461 tgccaatacc attttacctt atacgccagg aagtaccttt acggttgaaa atgcttataa
     5521 gcaaaatgga attgcaccag ccaatacaaa aagacaagta caaaccaatg ataatagcca
     5581 gacagatgat aatttgtctg atattcgagg gcgtgcgcaa agtctagtag atgaggctag
     5641 ccgggctatc tcagatgcga agattaagga aaaggctcaa acaatatggg attcgatagt
     5701 caatctattt cgctaagatg cttgtcaaag cctagctttc ttgttataat ggataagatg
     5761 gaggcgttat ggcactaaaa aaagcaagcc tagcttgtgc ggtttgtggt tcgagaaact
     5821 attcaatcaa gatcagcgga aaccccaagc ctacacgact agaagtaaat aaattttgta
     5881 agcattgtgg caagtacact acacacagag aaacgagata ggagagagcg atgcgtttta
     5941 ttggagatat ttttagactt cttaaagaca caacatggcc aactcgcaag gaaagctgga
     6001 gagattttcg ttctatcatg gaatacacag ctttctttgt agtaattatt tacatttttg
     6061 accagttgat tgtttcaggt ttgattcgat ttattaacat tttttagaag attagtggag
     6121 ttaattacac tagaaatctt ctatttatga aaggaaatat catggatagt tttgataaag
     6181 gatggtttgt tttacaaact tattctggtt atgaaaataa ggtgaaagaa aatctattac
     6241 aacgtgcaca aacctacaat atgttggata atattctacg cgttgaaatt ccaacacaaa
     6301 cagtgcaagt tgaaaaaaat ggaaagagaa aagaagtaga agaaaatcgc tttccaggtt
     6361 atgttcttgt agaaatggtc atgacagatg aagcttggtt tgttgttcga aacacaccaa
     6421 atgttacagg atttgtcgga tcacacggga acagatcaaa accaactcca ttattggaac
     6481 aagaaattcg tgacattttg gtatctatgg gacaaactgt tcaagaattt gatttcgatg
     6541 ttgagattgg tcaaactgta cgtattattg atggtgcttt tgcagactac actggtaaga
     6601 ttacagaaat tgataataac aaagtgaaaa tgattatctc tatgtttggt aatgacacag
     6661 ttgcagaagt aaacctaaac caaatcgc
//
LOCUS       DBEJJE010000069         6590 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEJJE010000069 DBEJJE010000000
VERSION     DBEJJE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.69"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..337
                     /locus_tag="ACL3F5_001899"
                     /pseudo
     CDS             1..337
                     /locus_tag="ACL3F5_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            504..704
                     /locus_tag="ACL3F5_001900"
     CDS             504..704
                     /locus_tag="ACL3F5_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515651.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            729..1145
                     /locus_tag="ACL3F5_001901"
     CDS             729..1145
                     /locus_tag="ACL3F5_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR0515652.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1376..2083
                     /gene="ccdA2"
                     /locus_tag="ACL3F5_001902"
     CDS             1376..2083
                     /gene="ccdA2"
                     /locus_tag="ACL3F5_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0515653.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2094..2651
                     /gene="sdbB"
                     /locus_tag="ACL3F5_001903"
     CDS             2094..2651
                     /gene="sdbB"
                     /locus_tag="ACL3F5_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0515654.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3025..4416
                     /locus_tag="ACL3F5_001904"
     CDS             3025..4416
                     /locus_tag="ACL3F5_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0515655.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4559..5476
                     /gene="adcAII"
                     /locus_tag="ACL3F5_001905"
     CDS             4559..5476
                     /gene="adcAII"
                     /locus_tag="ACL3F5_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0515656.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5484..>6590
                     /gene="phtD"
                     /locus_tag="ACL3F5_001906"
     CDS             5484..>6590
                     /gene="phtD"
                     /locus_tag="ACL3F5_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR0515657.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQP"
BASE COUNT         2016 a         1210 c         1385 g         1979 t
ORIGIN      
        1 aagaaccaca cctactatga acaagagcca gaaaaagtag ccttatttct taagaatttt
       61 aatagtttaa agcacctagc acctgtttag attgacgaaa caggatttga tacttatttt
      121 tatcgagaat atggtcgctc attaaaaggt cagttaagaa gaggcaaagt atctggaaga
      181 agatatcaga gaatttcttt ggttgcaggt ctaacaaatg aatggtgagt taatcgctcc
      241 aatgacttac gaagagacga tgacgagcga cttttttgaa gcttggtttc agaagtttct
      301 cttaccaaca ttaaccacac catcggttat tatagtaaaa tgaaataaga acaggacaaa
      361 tcgatcagga cagtaaaatc gaattctaac aatgttttag aagcctatat gtactattct
      421 agtttcaata taccataact gctcctagtc aacctgcaag tcctgtccca gctccaagct
      481 cagctccgac tcaagatcct agagtggtag caagcgcttc ggctagctca acgagcacac
      541 aagctcaaga gcaagttgac aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac
      601 gcttgaaagc tttggcaaca gtatctgatc caaaaatcga tgcaacccag gctgtcctcc
      661 tagatgctca aaaagctccg gaagatagtg ccttgacaga gtaaggtctg catactgcag
      721 tagagtctgt gaaggctgcc ttggactctc tcaaagatgt gaaagcaaat gctagcgaca
      781 gcaagcctgc acaggacaag aaggatgcaa aacaaggaac ggaagatagt aaggattcag
      841 ataagatgac tgaaacaaac tcagttccgg caggagtgat tgtggtcagt ctacttgccc
      901 tcctaggcgt gattgccttc tggctgattc gccgtaagaa agagtcagaa atccagcaat
      961 taagcacgga attgatcaag gttctaggac agctagatgc agaaaaagcg gataaaaaag
     1021 tccttgccaa agcccaaaac cttctccaag aaacccttga tttcgtgaaa gaagaaaatg
     1081 gctcagcaga gacagaaact aaactagtag aggagcttaa agcaatcctt gacaaactca
     1141 agtaaaacat gatttatgaa atgtcagacc taaaagacat tttcgttcac aaaagcagtg
     1201 acgagtaatc cttgtcgttg ctttttggct attttggggg ataagatccg ccttgactag
     1261 caaaagaaaa gattggtcca atagtgcccg atacgatttt gcgtagcaga aagcttacaa
     1321 ataaaattga atatagtaaa ataggattag aattattaag aaagttggtt ctttattgga
     1381 aacgatagta tttttaatct ctgtttttct agcaggtgtt ttatcctttt tttctccttg
     1441 tatttttcct cttctgccag tctatgctgg gattttattg gatgatcaag aaagtgcaaa
     1501 aagcttttct ttgtttggga gaaaggttct ctggtcaggc ttgattcgaa cactttgctt
     1561 tatcgctggt atctctctca ttttctttat tctaggcttt ggtgctggtt actttggtca
     1621 tattctctat gcaaattggt ttcgatatgt catgggagct attattatca ttttgggtct
     1681 tcaccagatg gaaatttttc atttgaagaa attagaagtt caaaaaagtt ttacctttaa
     1741 aaaatcagat tctaatcgtt attggtcagc ttttttactt ggtattacct ttagctttgg
     1801 ttggacacct tgtattggtc cagttttaag ttctgtttta gcacttgcgg cttctggagg
     1861 caatggcgct tggcaaggag cgatttatac tctcatttac actctgggga tggcccttcc
     1921 tttcttggta ttggcactag cttcaggtct agtcatgcca tattttagta aaatcaagcg
     1981 tcatatgatg ctactaaaga aaattggtgg tttcctcatt gttttaatgg gaattttgtt
     2041 actattagga caagtaaatg ttctagctgg aatttttgaa taaaggagga caaatgaaaa
     2101 aagtaatgtt tgctggctta agtctcttgt cattagttgt attgatggcc tgtggtgagg
     2161 aagaaactaa aaagactcaa gcagcacaac agccaaaaca acaaacgact gtacaacaaa
     2221 ttgctgttgg aaaagatgct ccagacttca cattgcaatc catggatggc aaagaagtta
     2281 agttatctga ttttaagggt aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc
     2341 catgcaagaa aagtatgcca gagttgatgg aactagcggc gaaaccagat cgtgatttcg
     2401 aaattcttac tgtcattgca ccaggaattc aaggtgaaaa aactgttgag caattcccac
     2461 aatggttcca ggaacaagga tataaggata tcccagttct ttatgatacc aaagcaacca
     2521 ccttccaagc ttatcaaatt cgaagcattc ctacagaata tttaattgat agccaaggaa
     2581 agattggaaa gattcaattt ggtgctatca gtaatgcgga tgcagaagca gcatttaaag
     2641 aaatgaacta gaatcgataa aatctgatta caagatgtag tcagattttg gtaacttcta
     2701 aaactaactt ccagtttccc acaacttagc ttttagtatg agaaaaacgc gtgacatcag
     2761 tggaaatccg tcttagacta acttccactg gttttctttt tcttgatata taagggttca
     2821 aaagcgaaaa gactcagaaa aagtgcacga caaatagccc taaaacagag tcgtcttaga
     2881 gtaacttcca gttttgggag agagatggaa gttactttga gaagttacgg tagtcagatt
     2941 tttttagaaa aacattttat aaatattcac atatctccta tatttatggt aaaatagaat
     3001 tatcagttta ttttggagtc aaagatgaat atatttagaa caaagaatgt tagtttagat
     3061 aaaacagaga tgcataggca tttgaagtta tgggatttga ttttgctggg tatcggagcc
     3121 atggtaggga caggcgtctt tacaatcaca ggtactgcag ctgcaacact tgctggccca
     3181 gccctagtga tttcaatcgt tatttctgcc ttgtgtgtgg gattatcagc cctctttttt
     3241 gcagaatttg cctcgcgagt acccgctaca ggaggtgcct atagttacct ctatgctatc
     3301 ttaggagaat tccctgcctg gttggctggt tggttaacca tgatggagtt catgacagcc
     3361 atatcaggcg tagcttcggg ttgggcagct tattttaaag gcttgctctc tcaatatggg
     3421 atagcccttc ctcaggcttt aaatggtacc tttaatcctc aagcagggac atttgttgat
     3481 ttattgccta ttcttgtctt ggtcttggtg acttcgcttg ttttactaaa tgccaaggca
     3541 gccttacgct ttaattcgat tctagttatt ttgaaatttt ccgctttagc tctctttgtt
     3601 ttagtaggaa tttggaatat taagtttgat aattggagca attttgctcc ttacggcttt
     3661 ggacaaatct atggagctag tactggtatt atggctggtg cgtccttgat gttcttcggt
     3721 tttttgggat ttgaatccat ctctatggct gtagatgaag tcaagactcc tcaaaaaaat
     3781 attcctagag ggattgtctt atcgctttct atcgtaacca ttctctatgc cttggtgacc
     3841 cttgttttga ctggtgtggt tcactatagt catttaaatg tcgatgatgc cgttgccttt
     3901 gcccttcgta gtgttgggat tagttgggca gccaactatg tgtcattagt ggctatcttg
     3961 accttgatta cagtttgtat ttcgatgacc tatgccctat cgcgtatgat ttacagttta
     4021 gcacgtgacg gcttagtgcc tgctgccttt aaggaattga cgaagactag caaggtacca
     4081 aagaatgcta ctatcttgac aggtctagct tcagcagtag cagcaggaat gttcccacta
     4141 gccagtattg cagccttttt aaatatttgt accttagcct acttgatcat gctggcttat
     4201 ggtctgattc gcttacggaa agaaaaagga atgcccaaag ctggggaatt taaaacacca
     4261 ttggtacctc tgttaccaat tttatcgatc atcatttgtt tatccttcat gttacagtat
     4321 aatatgaaca cctggattgc tttcctagtt gcgttgttag taggaagtat tatttacttc
     4381 acttatggct ataagcattc taccatagaa gaataaagtg aaagtctatt gagttgttga
     4441 cactcagcag atttttatat gtgaaagaaa tttcaaattt tttctaaaaa tatcttgaca
     4501 gattaaattt tcaggagtag aatatttact agttaattaa atggttaagg agttgttcat
     4561 gaagaaacaa aatttatttt tagtcctgtt aagtgtcttt cttttgtgct tgggggcttg
     4621 tggtcaaaag gaaagtcaga caggaaaggg gatgaaaatt gtgaccagtt tttatcctat
     4681 ctacgctatg gttaaggaag tatctggtga cttgaatgat gttcggatga ttcagtcaag
     4741 tagtgggatt cactcctttg aaccttcggc aaatgacatc gcggccatct atgatgcaga
     4801 tgtctttgtt taccattctc atacgctaga atcttgggca ggaagtttag atcccaatct
     4861 aaaaaaatct aaagtgaagg ttttagaggc ttcagaggga atgactttag accgcgtccc
     4921 aggactagag gatgtggaag caggggatgg agttgatgaa aaaacgctct atgaccctca
     4981 cacttggcta gatcctgaaa aagctggcga agaagctcag attatcgctg ataaactttc
     5041 agaggtagat agtgagcata aagaaactta ccagaaaaat gcgcaagcct ttatcaaaaa
     5101 agctcaggaa ttgactaaga aattccagtc taaatttgaa aaagcgactc agaaaacatt
     5161 tgtaacacaa catacagcct tttcttattt agctaagaga tttgggctta atcaacttgg
     5221 tattgcaggt atctctcctg aacaagaacc aagtccacga caactaacag aaattcagga
     5281 atttgttaag acctataagg tgaaaacgat ttttacagaa agtaacgctt cttcaaaagt
     5341 agctgaaact cttgtcaaat caacaggtgt gggtcttaaa actctgaatc ctttagagtc
     5401 agacccacaa aatgacaaga cctatttaga aaatcttgaa gaaaatatga gtattctagc
     5461 agaagaatta aagtgaggaa agaatgaaaa tcaataaaaa atatctagca ggttcagtgg
     5521 cagtccttgc cctaagtgtt tgttcctatg aacttggtcg tcaccaagct ggtcaggtta
     5581 agaaagagtc taatcgagtt tcttatatag atggtgatca ggctggtcaa aaggcagaaa
     5641 atttgacacc agatgaagtc agtaagagag aggggatcaa cgccgaacaa attgttatca
     5701 agattacgga tcaaggttat gtgacctctc atggagacca ttatcattac tataatggca
     5761 aggttcctta tgatgccatc atcagtgaag aacttctcat gaaagatccg aattatcagt
     5821 tgaaggattc agacattgtc aatgaaatca agggtggcta tgtgattaag gtagacggaa
     5881 aatactatgt ttaccttaaa gatgcggccc atgcggacaa tattcggaca aaagaagaga
     5941 ttaaacgtca gaagcaggaa cgcagtcata atcacaactc aagagcagat aatgctgttg
     6001 ctgcagccag agcccaagga cgttatacaa cggatgatgg gtatatcttc aatgcttctg
     6061 atatcattga agatactggt gatgcttata tcgttcctca cggcgaccat taccattaca
     6121 ttcctaagag tgatttgtct gccagtgaat tagctgctgc ccaagcctat tggaatggga
     6181 agcagggatc tcgtccttct tcaagttcta gtcataatgc aaatccagct caaccaagat
     6241 tgtcagagaa ccacaatctg actgtcactc caacttatca tcaaaatcaa ggggaaaaca
     6301 tttcaagcct tttacgtgaa ttgtatgcta aacccttatc agaacgccat gtagaatctg
     6361 atggccttat tttcgaccca gcgcaaatca caagtcgaac cgccaatggt gttgctgtac
     6421 cgcacggaga ccattatcac tttattcctt attcacaact gtcacctttg gaagaaaaat
     6481 tggctcgtat tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag
     6541 aacaaccaag tccacaatcg actccggaac ctagtccaag tccgcaacct
//
LOCUS       DBEJJE010000070         6494 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEJJE010000070 DBEJJE010000000
VERSION     DBEJJE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.70"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            120..1145
                     /locus_tag="ACL3F5_001907"
     CDS             120..1145
                     /locus_tag="ACL3F5_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0515658.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNILG
                     NACKNAK"
     gene            1135..2142
                     /locus_tag="ACL3F5_001908"
     CDS             1135..2142
                     /locus_tag="ACL3F5_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0515659.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2142..3149
                     /locus_tag="ACL3F5_001909"
     CDS             2142..3149
                     /locus_tag="ACL3F5_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR0515660.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3149..3943
                     /locus_tag="ACL3F5_001910"
     CDS             3149..3943
                     /locus_tag="ACL3F5_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515661.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVENLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            4094..4278
                     /locus_tag="ACL3F5_001911"
                     /pseudo
     CDS             4094..4278
                     /locus_tag="ACL3F5_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4331..4756
                     /locus_tag="ACL3F5_001912"
     CDS             4331..4756
                     /locus_tag="ACL3F5_001912"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0515662.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            4812..5144
                     /locus_tag="ACL3F5_001913"
     CDS             4812..5144
                     /locus_tag="ACL3F5_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGR0515663.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVE
                     KSSKDEIT"
     gene            5458..6494
                     /gene="mobQ"
                     /locus_tag="ACL3F5_001914"
                     /pseudo
     CDS             5458..6494
                     /gene="mobQ"
                     /locus_tag="ACL3F5_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
BASE COUNT         2588 a          883 c         1083 g         1940 t
ORIGIN      
        1 taaaaataaa aactagatcc ttttttgaaa aaattatatt attaaatttg taactgcatc
       61 tattgacaat gataattatt atcgatacaa tagacttgaa atatgtttaa ggagttttta
      121 tgaaaaacaa attttttcta atagctattt tagctatgtg tatagttttt agcgcttgtt
      181 cttctaattc tgttaaaaat gaagaaaata cttctaaaga gcatgcgcct gataaaatag
      241 ttttagatca tgctttcggt caaactatat tagataaaaa acctgaaaga gttgcaacta
      301 ttgcttgggg aaatcatgat gtagcattag ctttaggaat agttcctgtt ggattttcaa
      361 aagcaaatta cggtgtaagt gctgataaag gagttttacc atggacagaa gaaaaaatca
      421 aagaactaaa tggtaaagct aacctatttg acgatttgga tggacttaac tttgaagcaa
      481 tatcaaattc taaaccagat gttatcttag caggttattc tggtataact aaagaagatt
      541 atgacactct atcaaaaatt gctcctgtag cagcatacaa atctaaacct tggcaaactt
      601 tatggagaga tatgattaaa attgattcaa aagccttagg tatggaaaaa gaaggtgatg
      661 agttaatcaa aaatactgaa gctcgtatat ccaaagaatt agaaaaacat ccagaaatca
      721 aaggaaaaat caaaggaaaa aaagtattat ttactatgat taatgctgca gatacatcaa
      781 aattctggat ttatactagc aaagatccaa gagcaaatta tttaacagat ttaggtctag
      841 ttttccctga atcattaaaa gaatttgaga gtgaagatag ttttgcaaag gaaatttctg
      901 cagaagaagc aaataagata aatgatgctg atgtaatcat aacttatggt gatgataaaa
      961 ctcttgaagc tttacaaaaa gatcctcttt taggtaaaat aaatgcaatt aaaaatggtg
     1021 ccgttgctgt aattccagat aatacaccgt tagcagcctc atgcactcca acaccacttt
     1081 caataaacta tactattgaa gaatacctaa atattttagg aaatgcatgc aaaaatgcga
     1141 aataaaaaac aaataaacct aggcataatt tttgtaatct gcctaggtct tcttattaca
     1201 atatttttgt cattaaagct tggaacaaaa gaaattaata tcagagattt tttagcagct
     1261 tttggaatgg gcaatacaaa tgatgatttt attaaatcaa ttatatataa aagaatacct
     1321 agaactattt ttgcaatttt agcaggttct agtcttgcca taagcggtgt attgatgcaa
     1381 tcagttacta gaaacccaat agctgatcca ggtatactcg gtataaacac aggagcaagt
     1441 cttagtgtag taattggtct ttctttttta ggaatttcat caagcataag ccatataagt
     1501 tttgcaatca ttggtggctt agtaagtgca atttttgtat acgcgattgc tgtaagcgga
     1561 aaagcaggcc ttacccctat aaaactagcc ttatcaggaa cttgtgttag tatggcttta
     1621 agcagttttg taagtttttt aattttaccg aataataacg tcttagacaa atttagattt
     1681 tggcaaatag gtagccttgg agcagctaca ttatcttcta tatctacact actacctttt
     1741 ataattttag gtcacttgat agctatattt atttcatcag atttaaacgc tttagctatg
     1801 ggtgatgaaa tggctgttgg tcttggagtt aatgttaata ggataagatc acttgcaata
     1861 attgcaagtg tgcttttatg ttcaagtatt actgcaattg gtggacctat tggcttcgta
     1921 ggtcttatag ttcctcactt ttgtggctta tttataagca aagatatacg cacaatgacc
     1981 atttcttcat cttttatagg tgcagagctc ttgcttatat gtgatataat cggccgtatg
     2041 ttaggtaaac caggtgaaat tgaagtaggg ataattactg caataatcgg gggtccagta
     2101 cttatttatg taactatgaa aaatagaggg gttaataact aatgcaaaat ttaattatag
     2161 gtattcaaaa aagaaaaaat agaataacac tattttcctc actattttta ttaataataa
     2221 tcagtctatc atttttcatt ttacttatcg gagatgaaag ttattctttt tcaactttga
     2281 ttaaagtctt aaatagtgaa actgttcctg gagctagttt ttcgattatg gaaattagat
     2341 taccaaaatt attagcagga attatagctg gctggtcttt tggattggca ggatttatct
     2401 ttcaaactat gttaagaaat cctcttgcaa gtcctgatat aatcggtgtc acaagttctt
     2461 catctattgc agcggtcttt tgcatattgg tattaaaaac aaatagttta actactggaa
     2521 ttatttcaat aacttgtgga ctaacatcat ctttaatatt atttttacta gctaaaaaag
     2581 atggtttttc agcagcaaga ctgataatat taggtattgg ttttcaagct gtcacaagag
     2641 caggcacctc atttttattg ttgaaagtag caagatatga attacaagaa gttatgagat
     2701 ggctcagtgg ctctttatct tttacaaagt tagatgacat acctcttgtt ctaatagtaa
     2761 gtattattgc tactatatta gttttatttt ttaataaaag actagaaatt attgaacttg
     2821 gtgaagaaat agcaatcgga cttggagcaa atcccgagct ttcaaggctt gttttaattt
     2881 tttgcgctgt atctttaact gctttttcta cttcaattac aggaccaata gcttgtatat
     2941 cttttttagc tggtcccata gccttaaata ttggcaagaa aagaagccca atattagctg
     3001 gattggttgg aattttacta gttttgttat cagacatatt ctctcaaaat attttaccag
     3061 ctagatatcc agtaggtgtt gtaactggct tgttaggttc accatactta atatacttac
     3121 taataaaaat gaacaggagg aatatataat gaaaggtctg tggtcaaata atcttacctg
     3181 cggttatgat gaaaaaataa tcttggaaaa tataaatata aaaatacctg aagaaaaaat
     3241 atcagttatt attgggtcaa atggttgtgg gaaatcaaca ctcattaaaa ccttgtctcg
     3301 acttataaag ccattagagg gagaagtatt gcttgataat aaatcaatta attcttataa
     3361 agaaaaagat ttagcaaaac acatagctat attacctcaa tctccaataa tccctgaatc
     3421 aataacagta gctgatcttg taagccgtgg tcgtttcccc tacagaaagc cttttaagag
     3481 tcttggaaaa gatgaccttg aaataataaa cagatcaatg gttaaggcca atgttgaaaa
     3541 tctagcaaat aacctagttg aagaactttc tgggggtcaa aggcaaagag tatggatagc
     3601 tctagcccta gcccaagata caagtatcct acttttagat gagccaacta cttacttgga
     3661 tatctcatat caaatagaac tattagacct cttgactgat ctaaaccaaa aatataagac
     3721 aaccatttgc atgattttgc acgatataaa tctaacagca agatacgctg attacctatt
     3781 tgcaattaaa gaaggtaaac ttgttgcaga gggaaagcct gaagatatac taaatgataa
     3841 actagttaaa gatatcttta atcttgaagc aaaaattata cgtgacccta tttccaattc
     3901 gcctctaatg attcctattg gcaagcacca tgttagctct taataattga atatcggaat
     3961 tcatttaaaa gtcgcaaatt ttgaactgac cctcaaaagt taggccaaaa aactaactaa
     4021 aggaggtcag ttttttaatg gcaaatacag cacagaattt aagataaaat tagtaaaaga
     4081 atatcatgaa tgaaaaatag gatatagaga ataacagcaa tattaaaaag atcaggactg
     4141 ataataaaca aaaagaaagt acaacgacta gttcaaaagc taaaacttca agtaaaaagt
     4201 tattcaagaa aatctagaaa atactcatcc tacaaaggac aggtaggaaa aatatcagac
     4261 aacaaaataa aaagaaatat ttattaccga aaaaaagagg aaatcgagtc aagtaccaac
     4321 aggctcatct attccaaaaa gatatttact cgatggaaaa actcctagaa ttagtgctac
     4381 aaatattgac aatggtatct taggttacta cgaagatata gatgataaaa attatagagt
     4441 ttttgaaaat tttatatctg tttcattttt aggagcagtc ttttatcata aatataaagc
     4501 aagcctagat atgaaaattc attgtttaaa attaaaaaat aaagaattga ataaagaagt
     4561 agcattctat ttaacttcaa ttattaggca agctttaaaa aatactgaat ataaagatca
     4621 aatatctagc acagtattgc cagatatcaa aattaaatta ccgatagaca gtagaggtac
     4681 tccagattgg aattacatgg aaagatatat agaagactta aaattaaaat gcaatatagc
     4741 aaattataat atttaaaaca agaacgatta gaaataaaaa tctagtcgtt ttttatttta
     4801 agaaaggata catgatggca agtaaaagat taagtattga agaacagatt gaaaagaaag
     4861 aagaaagcat taagcaatta caaaatcaaa aaagacagtt gaagaaaaaa cttaatgaac
     4921 aagaaagaaa agcaagaaac aaaagactta tagaaaaagg tgcagtgttt gaaagtattt
     4981 ttgaagaaag tatttttgaa gaaagtattg atttaacaaa agatgaattt tataagttaa
     5041 taaaaacgtt aaatgatgaa gaaataagat taaacataat ggaaatttta gaagaaagaa
     5101 tagatgataa tgtagaaaaa tcatctaaag atgaaataac ataattgtcc cttggttaca
     5161 agggcgcaat tatacaccct aaagggtgct tgcgtcctgc ggagtcaaac ccttgcaggg
     5221 agcaacaacc attcgctttt taaaagtcaa gggtaaataa actcgctaag gctcgccctt
     5281 gacttttaaa atttgaaatg aaagtaacaa ttaagccgac atactgaaac aacaaaaatt
     5341 aattcagtag tcggcttttt taattttatc atttcaaaac gctcattcac aaagaggata
     5401 taaaaaaact attaagcctc cacctaaaac aacaaagaaa gaaaggaagt gataaaaatg
     5461 gcagacagtt ttcatttttc agtaaacata atatcaagag gaaaaggcaa aagtgcagta
     5521 gcaagtgcag catatataag tggagaaaaa ataaaaaatg aatgggacgg agtaacccat
     5581 gactacacaa gaaaagaaaa aatattagta aaaaatataa tattgcctga tcatatacca
     5641 aaagaattta atgataggtc taccttatgg aataaagtag aaatggcaga aaaaaattct
     5701 aatgcacaac tagcaagaca attcataata ggactaccaa aagagttatc tttaagtgaa
     5761 aataaaaacc tggttgaaag atatataaaa gaaaatttaa catcacaagg aatgatagta
     5821 gattatgcaa ttcatgatga gagtcaagat aaaaatggaa atatccattg tcatataatg
     5881 accataatgc gaccaataaa cgaaaaagga gagttcttag ccaagtcaaa aaaagaatat
     5941 atcctagatg aaaaaggaga aaagtattaa acaaaaatgg aaaaccaaag acaagaaaag
     6001 tagaactaac aacctggaac gatacaggca atatagaaaa atggagagaa aatttttcag
     6061 atctttgtaa caaatattta gaaagagcag gagcagaaaa aagagtagac cataggagtt
     6121 ttaaaagaca aaattcagat tatctaccga caatccattt aggatcagca gcaagtgcaa
     6181 tggaaagaaa gggaatagaa actgacaagg gaaactataa tagagaaata agaaaatata
     6241 atcaacttgt aaaaacaata aaagaagaga taaaaacatt aaagggttgg ataggaaatt
     6301 tattagataa cttatctact gcttatgaaa aatttaagga tatagaaaga gataaggtaa
     6361 tagacaaccc taaacttttt aatctaacaa attatctatt aacttattca gaaattcaaa
     6421 aagaaaaaag taaatatcta aaaggatatg caaaaactaa taaagaaaaa tatgacttca
     6481 aaaagctaac aagt
//
LOCUS       DBEJJE010000071         6434 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEJJE010000071 DBEJJE010000000
VERSION     DBEJJE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.71"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(123..419)
                     /locus_tag="ACL3F5_001915"
     CDS             complement(123..419)
                     /locus_tag="ACL3F5_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0515664.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(409..564)
                     /locus_tag="ACL3F5_001916"
                     /pseudo
     CDS             complement(409..564)
                     /locus_tag="ACL3F5_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
     gene            641..1405
                     /locus_tag="ACL3F5_001917"
     CDS             641..1405
                     /locus_tag="ACL3F5_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0515665.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1970..3349
                     /locus_tag="ACL3F5_001918"
     CDS             1970..3349
                     /locus_tag="ACL3F5_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0515666.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3363..4028
                     /locus_tag="ACL3F5_001919"
     CDS             3363..4028
                     /locus_tag="ACL3F5_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0515667.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4338..4877
                     /locus_tag="ACL3F5_001920"
     CDS             4338..4877
                     /locus_tag="ACL3F5_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0515668.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYKENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            4944..5354
                     /locus_tag="ACL3F5_001921"
     CDS             4944..5354
                     /locus_tag="ACL3F5_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0515669.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5470..>6434
                     /gene="pavB"
                     /locus_tag="ACL3F5_001922"
     CDS             5470..>6434
                     /gene="pavB"
                     /locus_tag="ACL3F5_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0515670.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLE"
BASE COUNT         1756 a         1232 c         1478 g         1968 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagca gcctgcgact aacttcctag tttgcacttt
       61 aattttcatt gagtattact tcatcttctc ctgaaattga gtttttgccc agctcctctt
      121 gattattcta cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg
      181 ccttgggagc tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaataaca
      241 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga
      301 tttttggcat ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt
      361 tctagatttt cattttgata ttttccataa aagtcagcca tgctgatact agtttccata
      421 ttctactcct tctgggttag tcattttgta tagtgaataa gcgccgtcaa ggttttggac
      481 ggtaaatcct gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca
      541 gctgacgatg taggcttgtt tttctcctca gttcatcagc ttcctccttg acactttgtc
      601 agattttgat acaatagtac aaaattagag gaggcaggct atgattcaga aacatgcgat
      661 tcctatttta gagtttgatg acaatcctca ggcggttatc atgcccaatc acgaggggct
      721 ggacttgcag ttgccaaaga agtgtgttta tgcattttta ggtgaggaga ttgaccgcta
      781 tgcaagggaa gtaggggcgg attgtgtcgg cgaattcgtt tctgctacca agacctatcc
      841 agtctatgtc atcaactaca agggtgagga ggtctgtctg gctcaggctc ctgttggctc
      901 cgctccagca gcccagttta tggattggtt gattggctat ggtgtggagc agattatctc
      961 tactgggacc tgtggtgtgc tagccgatat agaggaaaat gcctttctag tccctgttcg
     1021 cgctctgcga gatgagggag ccagttacca ctatgtggca ccttgtcgtt atatggaaat
     1081 gcagccagag gctattgctg ctattgagga agttttggaa gacagaggga ttccttatga
     1141 agaagtcatg acctggacga cagacggttt ttaccgagaa acggctgaaa aggtggctta
     1201 tcgtaaggaa gaaggctgtg ctgttgtgga gatggagtgt tctgctcttg cggcagtagc
     1261 tcaattgcgt ggggttctct ggggtgaatt gttgttcaca gcagattctc tagcggactt
     1321 ggaccagtac gacagtcgtg actggggctc ggaagctttt aataaggcgc tagaactgag
     1381 tttagcaagt gttcaccacc tttagttgta caggcaaagg atttgtttta tcataaaatg
     1441 tctagctcat acttttcaaa aatatgttta aacgaggtca ccttcctctt gtcctaggca
     1501 tgttgaggtt gggaaaaatc tttaaaatca gaaaaacgta tcatatcagg tgatgaaaat
     1561 tttgatacta tgcgttttat gttggtaaga tttagagtga gatgaaatga tactcttcga
     1621 aaatctcttc aaaccaggtc agcttcacct tgccgtatag atgttactga cttcgtcagt
     1681 tctatccaca acctcaaaac agtgttttga gcaacctgtg actagctttc taagcgatgc
     1741 cttggttctc attgcctata atcaaaaaga gaaattttct cctgaaaagc atatagagta
     1801 gctggcgtta aaagctcctg tcttgctttt ttgacctata gtcacatcta tcaagtattg
     1861 ttcttgccta agctatcaat aaaaaggtgg cattttttag gcttggtgtt agtgaatttt
     1921 gccttatcct atctaagtca tttcgagctt tttatggtac aatggaaaca tgttattcaa
     1981 attatctaag gaaaaaatag agctaggctt atctcgttta tcgccagccc gtcgtatttt
     2041 tttgagtttt gccttggtca ttttactagg ctctcttctt ttgagcttgc cctttgtcca
     2101 agttgaaagc tcacgagcga cttattttga tcatcttttc actgctgtct ctgcagtctg
     2161 tgtgacaggt ctctcaaccc ttccagtagc tcacacctat aatatctggg gccaaataat
     2221 ctgtttgctc ttgattcaga tcggtggtct agggctcatg acttttattg gggttttcta
     2281 tatccagagc aagcaaaagc ttagtcttcg tagccgtgca actattcagg atagttttag
     2341 ttatggagaa actcgatctt tgagaaagtt tgtctattct atttttctca cgaccttttt
     2401 ggttgagagc ttgggagcta ttttgcttag ttttcgcctt attcctcaac ttggctgggg
     2461 acgtggtctt tttagttcca tttttctagc gatctcagcc ttctgtaatg ccggttttga
     2521 taatttaggg agcaccagtt tatttgcttt tcagaccgat ttactggtca atctggtgat
     2581 tgcaggcttg attattacag gcggccttgg ttttatggtc tggtttgatt tggctggtca
     2641 tgtaggaaga aagaaaaaag gacgtctgca ctttcatacg aagcttgtac tattattgac
     2701 tataggtttg ttgttatttg gaacagcaac tactctcttt cttgagtgga acaatgctgg
     2761 aacgattggc aatctccctg ttgccgataa ggttttagtt agcttttttc aaacagtgac
     2821 gatgcgaaca gctggctttt ctacgataga ttatactcag gctcatcctg tgactctttt
     2881 gatttatatc ttacagatgt ttctaggtgg ggcacctgga ggaacagctg ggggactcaa
     2941 gattacgaca ttttttgtcc tcttggtctt tgcacgaagt gagcttctag gcttgcctca
     3001 tgccaatgtt gcgagacgaa cgatcgcgcc gcgaacggtt caaaaatcct ttagtgtctt
     3061 tattatcttt ttgatgagct tcttgatagg attgattctg ctagggataa cagccaaagg
     3121 caatcctccc tttatccacc tcgtatttga aaccatttca gctcttagta cagttggtgt
     3181 aacggcaaat ctgactcctg accttgggaa attggctctc agtgttatca tgccacttat
     3241 gtttatggga cgaattggtc ccttgacctt gtttgttagc ttggcagatt accatccaga
     3301 aaagaaagat atgattcact atatgaaagc agatattagt attggttaag aaaggaaaga
     3361 gcatgtcaga tcgtacgatt ggaattttgg gcttgggaat ttttgggagc agtgtcctag
     3421 ctgccctagc caagcaggat atgaatatta tcgctattga tgaccacgca gagcgcatca
     3481 atcagtttga gccagttttg gcgcgtggag tgattggtga catcacagat gaagaattat
     3541 tgagatcagc agggattgat acctgcgata ccgttgtagt cgcgacaggt gaaaatctgg
     3601 agtcgagtgt gcttgcggtt atgcactgta agagtttggg ggtaccgact gttattgcta
     3661 aggtcaaaag tcagaccgct aagaaagtgc tagaaaagat tggagctgac tcggttatct
     3721 cgccagagta tgaaatgggg cagtctctag cacagaccat tcttttccat aatagtgttg
     3781 atgtctttca gttggataaa aatgtgtcta tcgtggagat gaaaattcct cagtcttggg
     3841 caggtcaaag tctgagtaaa ttagacctcc gtggcaaata caatctgaat attttgggtt
     3901 tccgagagca ggaaaattcc ccattggatg ttgaatttgg accagatgac ctcttgaaag
     3961 cagataccta tattttggca gtcatcaaca accagtattt ggatacccta gtagcattga
     4021 attcgtaaag agggatgacc cctctttttt gatgcctaag atggcaaata gagacagaag
     4081 ccccttgtct tctagtaaaa gttcttcaaa ggctggactt tatggtaaaa tagaaagaag
     4141 tgacaagaga gagtaatact caatgaaaat caaagatcaa actaggaaac tagctacggg
     4201 ctgctcaaaa cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac
     4261 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc
     4321 ccctaaagga gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag
     4381 cctatcttca ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga
     4441 ttatcaatga cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt
     4501 atcctaatat cgttagagcc atctataagg aaaataaatg ccatggcggt gcggtcaatc
     4561 gtggcttggc agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg
     4621 atcctcgtgc ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag
     4681 aggtggatgt ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga
     4741 gtatgagtta cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa
     4801 atttctccaa aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc
     4861 gtgctagcca gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta
     4921 cgccccttca gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga
     4981 ttgggcgtga ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac
     5041 tcaaggtcaa tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa
     5101 tgcgagaata tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca
     5161 accgatctgg aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc
     5221 agaaaaatcc agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac
     5281 attctgtctt gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt
     5341 atggatttaa ttaatataag tgttttataa gagggattta agaaaaattt taactttttc
     5401 ttagtccttt ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag
     5461 gagaatccta tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc
     5521 agtgtcggtg ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca
     5581 agttctgtac gtgccgatgg gctcaatcca accccaggtc aagtcttacc tgaagagaca
     5641 tcgggaacga aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg
     5701 aaacctgagg gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa
     5761 gtgagcgagg aaacaagccc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct
     5821 caaaaaaatc cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat
     5881 gggacacaag caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa
     5941 aatacaaaag acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt
     6001 cctttcactg ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg
     6061 ttaactcgtc tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct
     6121 aaaaatcctg ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta
     6181 gacttaaatg gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct
     6241 aatggtactc aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct
     6301 gacttgacta atctagttgc tactaaaaat gtagacatca acattaatgg attagttgct
     6361 aaagaaacag ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca
     6421 gcctacctag aaaa
//
LOCUS       DBEJJE010000072         6418 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEJJE010000072 DBEJJE010000000
VERSION     DBEJJE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.72"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..463)
                     /locus_tag="ACL3F5_001923"
     CDS             complement(<1..463)
                     /locus_tag="ACL3F5_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515671.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
     gene            complement(453..1448)
                     /locus_tag="ACL3F5_001924"
     CDS             complement(453..1448)
                     /locus_tag="ACL3F5_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515672.1"
                     /translation="MNVKKIMLIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYSGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(1857..2282)
                     /locus_tag="ACL3F5_001925"
     CDS             complement(1857..2282)
                     /locus_tag="ACL3F5_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515673.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEVASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2411..2770)
                     /locus_tag="ACL3F5_001926"
     CDS             complement(2411..2770)
                     /locus_tag="ACL3F5_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0515674.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKETVLG"
     gene            complement(2816..3022)
                     /locus_tag="ACL3F5_001927"
     CDS             complement(2816..3022)
                     /locus_tag="ACL3F5_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515675.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(3009..3170)
                     /locus_tag="ACL3F5_001928"
     CDS             complement(3009..3170)
                     /locus_tag="ACL3F5_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0515676.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3529..4485)
                     /gene="lytA"
                     /locus_tag="ACL3F5_001929"
     CDS             complement(3529..4485)
                     /gene="lytA"
                     /locus_tag="ACL3F5_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0515677.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4861..6231)
                     /locus_tag="ACL3F5_001930"
     CDS             complement(4861..6231)
                     /locus_tag="ACL3F5_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0515678.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLEVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMIVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2049 a         1340 c          996 g         2033 t
ORIGIN      
        1 aaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatgtaagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcaggatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcctttt
      661 aaaatatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacta
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatctact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga cttcagtatc attcgcattc agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gttagttcct caatactgac atcaacataa aaggattgaa aaattaacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tacatcctat aggctcaatt tgacactttt
     1681 ctttttcgaa ttgctcatat gcctcctgaa tagtgagttc gatttatcca aatttatttt
     1741 tgtctatttt gatgaatact tccacgaaga tagtctgaaa atgaatttgc accaattttc
     1801 cttctctttt taagcatatt attccagata tgattgccct cttgttcagt aataaattac
     1861 gctttaaacg cttcaatcag tatatctcct gttgtcatat gttctaaaga aaattcttct
     1921 acatatggtt taacatctct taggttatta cttcctaata tcccattatg ctttttcgct
     1981 aaggaaatag aagccacttc tcccttacca ataatcttgt tactatcatg atttcttgtt
     2041 aaatctctat ataatgcgta ttcttcagtt ccaatgtcta tgctcacaat ctcagctgaa
     2101 cccttagtta ccaactggtc tatcctagat tttaaatggg gaattgtagg tatattgatt
     2161 tcatcataca cctcttgtgg aataacaatt ttacccgaat agagcttttc taaaagatgt
     2221 tcagtgccaa cccataaaaa tactgaaata caatctgcat caataaatac acgactagtc
     2281 aaacgacaac tcccccctct tcatatagcc catatacaat atcatatctg aaagcatcta
     2341 gtaacagttc ctcatacttc ccttgcgaaa ttctgttatt ttctaaaagt tgttcagttg
     2401 aattaatata ttatcctaac accgtttcct ttttactttc tgacaaagga cgatataaac
     2461 ttgtatcata gcctaatctt gaagctgtct ctataacact aatatccata tttttaattt
     2521 cttctgcatc aaggtatcca tcattcctca atctatataa catagcttta tgactgatac
     2581 cataaaactg acccaatttt ataatatctt ctacttcaag atgagttcta ttggcatttt
     2641 ctctaatttc ctcaaccatc ctatacagtg aagatgggaa aattaaaaaa taagaagcaa
     2701 actgatccgc ttttctttca gtttcatctc cttcaccaat caagataaga ctgactgaac
     2761 tcttcttcac ctcatcataa taaagatgat acagttcatg tgctaaagaa aatctttacc
     2821 ttcctaatga catgtctgaa ttgactgcaa tgagactgaa ctgagttcct ttataacaga
     2881 ctccgctaat attctttccg agtccataaa ataccagcgt caaattttct atcttttgta
     2941 ccaatttaaa aatatctatc ggcgattcac catcagctcc caactttttt ctaagatttg
     3001 gagctttatt acttaaatcc attcgtgata ttcctttcac ctttttccat tttggcaatc
     3061 atgctttgat tcaaagacaa atactcagca atcttatctt gagtaagatt tgaagatatt
     3121 ctaagttctt ttattctttt tccaacatca catacattta tcacatacat ttatcatatt
     3181 catacacctc tcataaaaag aatagcacac tcttgtcata attttttaaa taaaaaaatt
     3241 atgacaaaac aaggaagcaa tttattgatg ctgcttaaaa atctaaaatt gatgagttcc
     3301 tatcaaaaat cgtatcttca acctcaaaac agtacttaaa gctatccgac tcggtttaca
     3361 ttgtcaaatt tagattttat ttgagcataa ctttctagtt tgctttctga tttttgttta
     3421 atatagtagc aaacattgaa ggaaatatct ccacaaaaaa acgcatacta ttaagctttt
     3481 tcaagaccta ataatatgcg ctgttctgat ttgaaagaca ttccattatt attttactgt
     3541 aatcaagcca tctggctcta ctgtgaattc tggcttgtct gccagtgttc cgtctggttt
     3601 gaggtagtac cagcctgttc cgtccgctga ctggataaag gcatttgata ccatggcgcc
     3661 ttctttagcg tctaagtagt accaagtgtc cttgtacttg acccagcctg tcttcatggc
     3721 accttcttcg ttgaaatagt accacttatc agcgattttc ttccagcctg tagccatttc
     3781 gcctgagttg tcgaaccagt accagttgcc gtctgtgtgc ttcctccagc ggtctgcaag
     3841 catatagcct gaactgtcaa agtagtacca agtgccattg attttctcaa acttgtcttt
     3901 tggataagag ccgtctgaat gtacgtacca gtagccagtg tcattcttct gccagcctgt
     3961 ttcaatcgtc aagccgttct caatatcata cttaaactgc tcacggctaa tgccccattt
     4021 tgccaagtaa gggtatggat ccacatggtc tgagtggttg tttggttggt tattcgtgca
     4081 atactcgtgc gttttaattc cagctaaact ccctgtatca agcgttttcg gcaaacctgc
     4141 ttcatctgct agattgcgta agagttcgat ataaaggcgg tagtccgtca tgaactcttc
     4201 tttagttgaa tggctttcaa tcagttcaac cgctgcatag gtctcagcat tccaaccgcc
     4261 cccaacgtcc caggcaccat tatcaacagg tcctacctgc atgatgcaac cgttcccaac
     4321 aatgtgcgag aaaaaaccta attctgggtc tttccgccag tgataatccg cttcattctg
     4381 tacggttgaa tgcggattcc cagttgagtg tgcgtgtact tgcctatatg gttgcacgcc
     4441 gacttgaggc aaatctgttc ttaatttact cacattaatt tccatattct actccttatc
     4501 aattaaaaca actcattttt tacaatccag aaccagaaac tcctttattt ctaccttaca
     4561 aagaagacaa tcttagtcac gattaggctt gtagatagaa cctcaaaacg cactattttg
     4621 acactgtaaa taggactgac aaggtctgca ttctatctac aataacaccc cagactaaaa
     4681 agcttttcaa aagtatattt ttacagtctc tatatatcct tttcataaat actatacttt
     4741 attatatcat ataaaagaag tcaaaagtct gttaaactat tttcaacacc aaactaaaga
     4801 agagaacaca agttttttcg atgttcacta gaggaaatgg attttattca gtaaatccaa
     4861 ctaggattgc actttggttg ccaaaattgc ctttccttct tttatcaagg gatgacggaa
     4921 tagtgagaag tacagttgaa ctatcatggc aacccagata agaggttcac aaaggataac
     4981 acccttatat cctgcccaag gaataatcaa aaccacaaaa acgatttttc cgattagttc
     5041 aataaagcta gaaactagag gaaggatctt ctgccccaag ccctgcaagc aattgcgata
     5101 aatcaacaag aggctcaaaa tgggataaaa ggctgaactg atttgcagat agagacttcc
     5161 attttctatc aagtaaccat ctgtcgaact agccaagaag gaaaccaagg ctggactggc
     5221 aaaaaagagg aaaatacaaa caaaaactgc ccaggatata cttaaacgac tgccgattcg
     5281 aagaccttga acaatgcggt caggtcgctt agctcctaga ttctgagaag caaaggtcgt
     5341 cattgatgca gaaatagcgg tcataggaag aagggcaaag gtcataatgc gtcgagctgc
     5401 cgtctgggca ctaataatca ctgcaccaaa tgtattaaca gaaaactgta aaatcacact
     5461 gccgatagat acaattgaac tcatcaagcc catagccaaa ccttgctcca agagatccgc
     5521 gtacaagctt ttgtcccatt tgaaatgttt aaaccgtggc aagagttctg gcacactttt
     5581 acgaatataa taaaagcaga gaaccgctga taaaccttgc gaaataatgg tagcaagtcc
     5641 tgcggattga acttccagat gcaattgcgt aataaaatag agatccagaa ccacattaac
     5701 caaggcagag aaaatcagaa atcccagggc tgctagactg tcaccaatag accgcaacaa
     5761 gcctgcaaaa agattataag caaagctgac acctacacag gtcacaatca tagaaatata
     5821 ttgataagat tgaggaagaa tttctgcagg agtatctaag tattgcaaga gaggatacaa
     5881 gccaagaaag cccagcaaca taactagaat gctcaaaaga gcacctaaaa tccaggtggc
     5941 tgctactgct tccttgattt tagtgaaatt cctagcccca taataacgag caatgacaat
     6001 ccccatgcca ttgccaacac caagtgtaaa acctacaatc aggtcaaaaa tcgctgtcgt
     6061 cgctcctact gcagccaagg attcttgacc aagaaatcgt ccaacaatca agacatcagc
     6121 agtgttatag agctgttgaa aaatatttga tagcaagatt gggaaggcga agcttaagag
     6181 cgagggaaga atcggaccat gtatcaggtc cactgttcgt tttttattca taaagctatt
     6241 atatcagctt tccagaggag cgacaagaaa cagcaaacta tatatagcgg aatgaaataa
     6301 ggacagtcaa atcgattttt aacaatgttt tagaagtaga tgtgtactat tctagtttcg
     6361 atctattata attggttgag tttggaatag tacgctgtag ctgctaaaac atttctag
//
LOCUS       DBEJJE010000073         6186 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEJJE010000073 DBEJJE010000000
VERSION     DBEJJE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.73"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(137..316)
                     /locus_tag="ACL3F5_001931"
     CDS             complement(137..316)
                     /locus_tag="ACL3F5_001931"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0515679.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRME"
     gene            complement(648..755)
                     /locus_tag="ACL3F5_001932"
                     /pseudo
     CDS             complement(648..755)
                     /locus_tag="ACL3F5_001932"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
     gene            1555..2427
                     /locus_tag="ACL3F5_001933"
     CDS             1555..2427
                     /locus_tag="ACL3F5_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0515680.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="ACL3F5_001934"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="ACL3F5_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="ACL3F5_001935"
     CDS             3060..3371
                     /locus_tag="ACL3F5_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515681.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4073
                     /locus_tag="ACL3F5_001936"
     CDS             3375..4073
                     /locus_tag="ACL3F5_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0515682.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALFDTIFLENFGHELYTQAPK
                     EIAILMNEWLAYFL"
     gene            complement(4202..5017)
                     /locus_tag="ACL3F5_001937"
     CDS             complement(4202..5017)
                     /locus_tag="ACL3F5_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0515683.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5014..5919)
                     /locus_tag="ACL3F5_001938"
     CDS             complement(5014..5919)
                     /locus_tag="ACL3F5_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0515684.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(5920..6051)
                     /locus_tag="ACL3F5_001939"
     CDS             complement(5920..6051)
                     /locus_tag="ACL3F5_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0515685.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
BASE COUNT         1960 a         1072 c         1236 g         1918 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttac tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctatt ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgacaactt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat ttgggattga gtttttttaa ggtagccttg gcggagtttc
      601 ttgacatagt tagcgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccatatct aaatcgttgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg agaaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatgtttttc acctctaaca atcgcaatct cttctttatc tacgaatgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag cttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagctt tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccaatt gcttttccta gataacgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttaggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgatgac ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacta ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga ttaagttgct ttcgtgaaca ccaaaatcag
     2701 ccgcaatttc ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt
     2821 ttaatacagc taacatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc
     2881 gtgcatcagt tagttgctta cttgcttcat aattcataga actactatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtacca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaaca ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcaat gcctatcata
     3421 gcaaggattt tcttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa tgagattgta gaggaagaat
     3541 ctatctgtct gataggccat tctcttggag gagatttagc tcgttatctc gcatcggaat
     3601 ttgaagaagt aaaaaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attgttttgg
     3721 acttagctct tcttatttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtct tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct atttgatact atttttttag aaaactttgg ccatgagctt tatactcaag
     4021 cacctaaaga aatcgctatt ctaatgaatg agtggctcgc ttattttcta tgagctactt
     4081 gtattgctgg aaatggtata agatgaaaat ctacaagtca ctaattttca tataacaaaa
     4141 aacgaacagg ctctttttct gttattcaga agagaacttg ttcgttttta tcttgatttt
     4201 cttaaaaagc tctatataca tagggatttt ctggtttatc gactttggta aagctgtcga
     4261 tttccaaggt tggaaggttt tgtttgagtt ctttatggta gtgattgacc agttttcctt
     4321 tggctgttat ccaagtgttg ttttcatact gccgggtatt gcccttggtc agcaatccat
     4381 agacaccaga atctgcgata cagtggataa tgccgaagcg gaacagaaat tggctattgg
     4441 catgactggg gtcgttatag acaaagcctg taaactggat tgtcttgccc tcaaactcat
     4501 ctggatagtc gtagatagcc tccatgactt ccatatagtt ttcattagtg atctgaatac
     4561 tatcttggga taagtattta tccgccgccg ttcgcatttc cttttcatag gctgattttg
     4621 aaaaataaga actggtatct ggtttcaaat attggcttgt cgtcccttcg cttgtctgaa
     4681 tggctagatc cgttccttct gataggggga aatgataacc tttagcagaa acggtctgag
     4741 aatccaagct aacagttggg aaagttaagc cgatgacaag tggaatagcc agaagagaaa
     4801 tactcgtcat cttggctaat cggctgttca gatgactgtg ggttttgact tgcttcatcc
     4861 agatatacaa ttgaacaata gccaagataa aggaaagcac catggaaata taggccagat
     4921 aggaatagtg catgttgatg tactggttta gtttgcccga cagatggagg taaatagtca
     4981 gttcaaaata gccagctaaa actaaaaatc gaatcatagg atgactccaa tcaagagaga
     5041 ataggctaaa acgaccagag tcacaatcgt aatgaagtga ctaataaatc gtgctttcaa
     5101 gtaatttttc atcatgagaa tatttttgat atccagcatt gggccaatga cgagaaaggc
     5161 cagaactgga gccaaaccga aactcgagag tagagaagca cctataaagg catccgcctc
     5221 actacagagc gaaagaagaa aggccaaaag catcaagagc aggatggcaa aaagaggagt
     5281 cgcactgata gaggtcagaa tccgagtcgg aacgtagacc tgtattatag aagcaaagag
     5341 gcagccaaat accaaataac gccccgtatc aaaaaattca tcaatggcct gcacaaagac
     5401 ttgaaaaact ttttttgcag aactcaagta agaaaaatca tgctcatgac aagccagacg
     5461 attttctttc tgaatcggtt cttgccagaa aaatcctaga aaaattccta gtattacagc
     5521 cacaagaatg gaacccagag ctcgtaatag ggcgacatgg aaggagttgc caaaggcaga
     5581 ataggtcgca aaaagaacaa tgggattgat aacaggtgct gtcacaagaa aaggaacggc
     5641 cgtgtaactt ggaacctttt tttccagaaa acgattgatg atggggacga ttccacattc
     5701 acaagaaggg aaaagtatac cgacaaaggt cccaaaaaag attctccccc aacgatttcg
     5761 agggagaaaa tgataaacct tgtcaggtgt gatataaact tcaatcagcc ctgagacaat
     5821 gcttcctatc agaacgaagg gaagggcttc aatgataatg gagagaaaaa tggctccagt
     5881 ttgaagtaca ctagatggga gttgttgaaa agcagtcatc tagtttttct tttctgcttt
     5941 gacttttttc tctttgtcat cagggaaagt aacttgtttc aaatcaggga gtttagcaaa
     6001 ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat ttgacagcca taggtgtacc
     6061 tcgattctaa attctacctc tattatacta ttattttgcg gaaaagggag ttttttaatt
     6121 tgttttcgat agttgatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttacc
     6181 gtagta
//
LOCUS       DBEJJE010000074         6156 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEJJE010000074 DBEJJE010000000
VERSION     DBEJJE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.74"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(52..153)
                     /locus_tag="ACL3F5_001940"
                     /pseudo
     CDS             complement(52..153)
                     /locus_tag="ACL3F5_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            complement(378..1238)
                     /locus_tag="ACL3F5_001941"
     CDS             complement(378..1238)
                     /locus_tag="ACL3F5_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0515686.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1254..2531)
                     /gene="spxR"
                     /locus_tag="ACL3F5_001942"
     CDS             complement(1254..2531)
                     /gene="spxR"
                     /locus_tag="ACL3F5_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0515687.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2524..3075)
                     /locus_tag="ACL3F5_001943"
     CDS             complement(2524..3075)
                     /locus_tag="ACL3F5_001943"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515688.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3091..4350)
                     /locus_tag="ACL3F5_001944"
     CDS             complement(3091..4350)
                     /locus_tag="ACL3F5_001944"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0515689.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            5619..>6156
                     /locus_tag="ACL3F5_001945"
     CDS             5619..>6156
                     /locus_tag="ACL3F5_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGR0515690.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGTPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNII"
BASE COUNT         1906 a         1376 c          995 g         1879 t
ORIGIN      
        1 aactactata ccatattttg tttcgcaggg agtctaatat aaaaaaataa atttaagatt
       61 ggcaatacga acgttaaaca gaattccatt tctcttttta gaatcaaaac gacaatattg
      121 tggaatctct acaggaacaa tagactgcga cactaaaata tcctccctta gttttacttt
      181 actaatagta tataggagga gagccctgaa tcctagaccc tttgttatga tgcgcttaca
      241 aacagagttg gaaaaaatct taaaagcaga aaaacgcatg atatcagccc ctaacacttg
      301 atacaatgcg ttttattatg aaaaaatcta ctggattttt tatcaaaata aacttccagt
      361 agtcttttca ctttttatta ataagttcct tcttcacctt ggctagtcaa gataacaggt
      421 ccatctttcg taatgacaaa ttggtgttca tactgacatg acaatccacc gtcaatggtc
      481 ttatgcgccc aaccagtttt catatctgta tcaatttccc aatcgcctgt attgatcatt
      541 ggttcaatgg ttaagaccat tccttcacga agacggagtc cacgacctgc aataccatag
      601 ttaggaacca ttggttcttc gtgcatagtt gggccaacac catgaccaac caaatcacgc
      661 actacaccgt aaccacgact ttcagcgtat tcttgaatag ccgcaccgat atcaccgata
      721 cgatttccaa caacagcttg ctcaataccc ttgtacatag cttctttggt tacatccatc
      781 aagtttttga cttcttcgga cggtgtacca acagcataag cccaacatga gtctgctaaa
      841 ccaccagaat agctctgagt gtattttttc atttgttcaa cattgttgaa gtttaatttt
      901 gagacattta ggtcagattt agcaatggga cctcccaaaa ccatatcaac tttgagcaaa
      961 tcaccatctt tcaagatata atgacgaggg aaagcgtgag ccacttcatc gttaagagag
     1021 caacaggtag cataaggata gtccatcatg gcaccgtcaa ccccaatctg aagtggaagg
     1081 aaattttctt ctttacaacg acggcggaca tattcttcaa cttcccacat atctacgcct
     1141 ggcttaatca aatcacgtaa gcctatatga atacttgcta gaaaatcacc agccttgtcc
     1201 atagcttcga tttcacgagc tgattttaat gttatcatct tttctcctag tttctaatta
     1261 attttaacag tcacatttgc ttttgaaaca atctggtgac catgataaat atcgtaatca
     1321 attatagctg accgtctcgt atgatgaata atccgtgcct gaatgcgcaa tatatcatct
     1381 atctgaacag cctgcaaaaa gtagatcagc atctgctcga taatgagatt gcgaccacta
     1441 ttaacaacta aatcttgggt catgtgggtc agaatttctg ccaatacacc attagccaaa
     1501 actccatttt tttctagcat aaagggttcc actgtaatga ctacttcatc atggtgataa
     1561 gagagctttt gtccaatctg ctcagaaaaa gttggtagag ccgaaacttg ggaacggctc
     1621 atcttctcca tgacatctcg tcgcgtcaca acgccaagca aagtttgatt gcttcgaaca
     1681 actggtacca tttcaaagtc ttctgcgatc atccgttgac tcacattggc aatatttgtc
     1741 gataacccaa ccaaaaatag actacgagac ataaccttat caattgtcgt gcttggtgat
     1801 ttatcaccag cgtctctcat ggttacaacg ccaacaacga cctgatgttg attgataaca
     1861 gggaaacggc tgctacgatt cttacgaacc aagtccaaat aatctttaac tgtatctgtc
     1921 tctctcagaa aaccatactc atgactaggg cgataaagtt tctcaactgt cagaatatca
     1981 gtcttgattt ggacatttga caaggcttta ttgatcatgg tcgcgacggt aaaggtatca
     2041 tgcttacttc ttagaacagg aatccctttt tgattggcca gtttaagcac atcatcatga
     2101 acctgaaatc cccctgtaac cagaactgca ttttcatttt ccaaggctag caactgaata
     2161 cgggttcggt ctccgacaat caagagcccc ccatcatgaa ggtaagacaa gatattttgt
     2221 tcagtcatgg caccaattga aaacttacta aactctctct ctaaaccttc ttgcccagcc
     2281 agaacctcag aagaagtcac ttctgcaatt tcagcaaacg ttaatctctc tatagcaact
     2341 ttctgggatt taacacgaat tgttccactt ctaggacggg tctccacaat tccacggttt
     2401 tcagcttctt taatagcccg ataggctgtt ccatcactaa ctcctagatg attcgaaatg
     2461 ctacgaacac tgaccctttt acctactggt aattcctcca aatagcttag aatttcctga
     2521 tgcttactca ttgaactctc cttttacata ccgaaattca agataatccc gcatttttct
     2581 tgtgtaacga tcacttccct taaactgacg gaacaaacta aatccagact taagagcaac
     2641 tctttggcta gcttcatttt caaggtgggt aatgatagat aattgtttta agccaaattc
     2701 ctcaaaagaa agctgacaaa tttttctaac aacctctgtc ataaatcctt gcgaccaagc
     2761 atcttttctc aaaaaatagc caagctcagc ttcttttttg atttcatcta acttctcaaa
     2821 tttaatagaa ccaatcattt gttgattttt ctggtcacaa attgcccaca ctcccaaagg
     2881 ggacttcata aagtaattgg ccagtgcata ttgactttct tccagacttg cctgcgttgg
     2941 gaaaataaat tgaagatttt ctggatttga agctatctcg cggaagtcct gactatcact
     3001 aaaaaagaaa ggacgcaaat acaagcgatc cgtttcaaaa aaagaaaaca ttgctaattt
     3061 ggtccaaata ttcataaaca cctctacggt ttaatcctca acaagtctaa tatccgctcc
     3121 taaattacgt aatttttcga taatatcaga ataaccacgt aagataaact cgatattggt
     3181 aatttcagtt ttgccttcag ccataagccc agcaatgact agtgcagccc cagctcttaa
     3241 gtcggtcgct ttaacactgg ccccacgtaa atcacgtcca cccgtgtaca aaatatgacc
     3301 atttgttgtc gaaatatccg catccatctt tgctagttca aaaacatgat ttacacgttt
     3361 ttcgtaaatc gtatcgacaa ttgtaccacg accattcgct cttagtaaaa gaggggtaag
     3421 cggttgttgc aaatcagttg caaagcctgg gtaaggagct gtcttaatat tgattgcttt
     3481 caaattagac tgttcctcga caaaaatgct gtcttcagat acagtcattc tcactcccat
     3541 ttcttccaac ttagcaataa acccttccag gtgttcgtaa agaacattat ttatacgaat
     3601 tcctttacca actgcagcag ctaaagatat atatgttcca gcttcaatgc ggtctggaat
     3661 cacctgatga cgtgtcccat gtaatctttc aacaccatca ataatgatga tattagttcc
     3721 tgccccacgg atatgggcac ccatattatt caagagagta gctacatcaa taatctcagg
     3781 ttcacgggct gcattttcaa taatagtacg accatttgct ttaaccgcag caatcatcgt
     3841 attaatcgtt gctcccacac taaccgtatc catgtaaata cttgcaccat gaagtcctgt
     3901 atctttagca gataacttca tgttatctcc ctcgtagcta gcagtggcac ccatagcttc
     3961 aaacgcctta aggtgtaagt caatcggacg aggaccaaga tcacatcctc ccggtagacc
     4021 aactgtcgct tcaccaaaac ggcctaagag gctcccataa aaatagtaag atgcacgaag
     4081 actgttaatt ttaccataag gcattggaat attttgaaca cctcttgggt caatctccaa
     4141 tacatcgtca taacgcttaa cagtagctcc catcaattcc atgatttcga caagactggc
     4201 tacatccgaa atatctggaa cgcaatccaa agtcaccaca tcatcagcca agataatagc
     4261 tggaattaag gcaacgacac tatttttagc accactaata gtgatttcac cttgcagtgg
     4321 taatccacca ttgataacaa tttttctcat tctaagtttt caatactctt tcaagatttc
     4381 taataaggtc ttcaaaataa agtatatcat aaatttatcc ttttttccat ccttttcaat
     4441 tttattggat aaatcagagt tgacgagtta gtaactgaat tactaatact caatgaaaat
     4501 caaagatcaa actaggaaac tagccgcagg ttgctcaaaa cactgttttg aggttgtaga
     4561 tggaactgac gtagtcagta tcctacatat acggcaaggc gatattgacg tgatttgaag
     4621 agattttcga agagtataat ctttctcgaa tcgctattgc ccctttttta tcccctaaaa
     4681 ctgagtagga tctaagacta gatctcttat ctaagtatcg gaatacggct gttcaactaa
     4741 attttagcaa gaacttctcc ccttctctca gttcacagaa gcgttttata cataccgtcc
     4801 tatcagacaa tctattttaa agataaccgt gactcaggat cacttctatc tgtcgttttc
     4861 tctttatagt gatagacctc acgggataag tcgtacatct ttcctcgtgt atacaagata
     4921 taaggacgtt aaaaggttac agtgaaaata gaaaatctta gtacgaattc aattactctc
     4981 gtgatttacg catataggtt acgactacct ttttggactt tagagtttga gaccccctta
     5041 tccgctatat acgccttact atcacgttcc tgttcgtaaa gccacgattt cgctatccct
     5101 tcctctgacg attcttattt ccagcgtcag acttaaaacg gtctatcccc agaccgtttt
     5161 aatccactac ctcacgatag tcaggcttgg gaatcgctat ttgactcgcc gagaactttg
     5221 acatcagata tactataaca aattgaaata agaatcaaac aatttaattt tgaaattcaa
     5281 atcaatttat aacaatatag ttgattgaaa ctagactagt acacctctgc ttctaaaaca
     5341 ttgttagaaa tcgattttac tgtcctgatc gatttgttct gttctcattt cattttacta
     5401 tattttagaa gatatgctgt gctattccag attcagttcg ctatacatgc ccgtcgtacc
     5461 acaaaatccc gtgtttgatg tggcacggga tttttggctc tataatattt gtagtgggta
     5521 aatccactat agatattatg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
     5581 taatgaaaag cgacaaaacc atcattagaa aaattcatat ggaacaatta cattttatca
     5641 caaaactgct cgatattaaa gacccaaaca tcaagattct agatatcatc aatatggata
     5701 cccacaaaga aattatcgct aagctggatt atgaggctcc atcttgccct gattgtggaa
     5761 gtctaatgaa gaaatatgac tttcaaaaac cttctaaaat tccttatctt gaaacgactg
     5821 gtacgccttc tagaattctc cttagaaagc gtcgtttcaa gtgctatcac tgttcaaaaa
     5881 tgatggttgc tgagactccc ctggtaaaga aaaatcacca aatccctcgt attatcaacc
     5941 aaaagattgc tcaaaagtta attgaaaaaa tttctatgac tgatattgcc catcagctgg
     6001 ccatttcaac ttcaactgtc attcgcaagc tcaatgactt tcactttgag catgattttt
     6061 ctcggcttcc aaagattatg tcttgggatg agtatgcctt cactaaggga aagatgagtt
     6121 tcattgcgca agattttgat aatcttaata ttatca
//
LOCUS       DBEJJE010000075         5906 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEJJE010000075 DBEJJE010000000
VERSION     DBEJJE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.75"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(184..1194)
                     /gene="ccpA"
                     /locus_tag="ACL3F5_001946"
     CDS             complement(184..1194)
                     /gene="ccpA"
                     /locus_tag="ACL3F5_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0515691.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYTYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1619..2218)
                     /locus_tag="ACL3F5_001947"
     CDS             complement(1619..2218)
                     /locus_tag="ACL3F5_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0515692.1"
                     /translation="MKLLVAEDQSMLRDAMCQLLTLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2220..3317)
                     /locus_tag="ACL3F5_001948"
     CDS             complement(2220..3317)
                     /locus_tag="ACL3F5_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0515693.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGLLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESTAAMILLELVTNIIKHAKAFKVYLKLERTEKELILTVRDDGCGFTSIKGDDLHTVR
                     DRVLPFSGEVKVISWKQPTEVQVLLPYKERN"
     gene            complement(3317..4054)
                     /locus_tag="ACL3F5_001949"
     CDS             complement(3317..4054)
                     /locus_tag="ACL3F5_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515694.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSSMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLASWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELIKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(4056..4940)
                     /locus_tag="ACL3F5_001950"
     CDS             complement(4056..4940)
                     /locus_tag="ACL3F5_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515695.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(4927..5121)
                     /locus_tag="ACL3F5_001951"
     CDS             complement(4927..5121)
                     /locus_tag="ACL3F5_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515696.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(5118..5324)
                     /locus_tag="ACL3F5_001952"
     CDS             complement(5118..5324)
                     /locus_tag="ACL3F5_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515697.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1889 a         1316 c          955 g         1746 t
ORIGIN      
        1 agtttcatct acaacctcaa aaacatgttt tgagctgact tcgtcagttc tatctacaac
       61 ctcaaaacag tgtgttgcgc agcctttaac cagccgccta gtccgctcta tggtattcat
      121 taagtcaaca tctcttgttt aagagcacaa aatcaggaaa tcttctcgat tccctgattt
      181 tttctattta cgttttcgtg ttgagctacg ttctgtcaaa ccatgaggta agagaacttc
      241 acgttcttcc aactcttcct tatgcataat cttggtcaac atacgcatac taatggcacc
      301 aaggtcataa agaggttggg caatcgttgt caagtttgga cgggtaaagc gtgagatttg
      361 tgaatcatca ctagtaataa tttcaaaatc ttctggcaca gaaacaccct tatcagccaa
      421 accgttcaag actcctgctg ccaactcatc acctgtcaca actgctgcag ttgcatttga
      481 tgaaatcaaa cgctctgcta aggcgtaacc atcatcatag gtatatttag attcaaatac
      541 caaaccctca ctataagcga ttcctgcttt tttcaaggtt tccttgtagc caactaaacg
      601 aaccttacca ttgatgtcat ccactagcgg accgctaacg aaagcaatac gctcattttc
      661 tttagcaagg taactcactg catcaattgt tgcttgctta tagtcaatat tgacacttgg
      721 caactggtgc tcaacatcga cagttcctgc gagaacaatc ggagtacgtg aacgcgaaaa
      781 ttctgagcga attttatctg tcaagtgata acccatatag ataatgccat ctacctgctt
      841 tgaaaagagg gtattgacaa cagaaacttc tttctcgtta tcttcatcgc tattagctag
      901 gacaatattg tacttgtaca tttctgcaat atcatcaatc cccttagcca aactcgaaaa
      961 ataaccattg gtaatatttg gaatcacgac accgacagtg gttgtctttt tacttgcaag
     1021 accacgcgca actgcatttg gacgataatc caagcgatca attacctcta gcactttttt
     1081 acgggtattc tcttttacat ttttattgcc attgaccaca cggctgaccg tcgccatgga
     1141 aacacctgct tcacgagcga catcataaat ggttactgta tcatctgcat tcattccttt
     1201 tcctgtcctt tctatctcac acattctttt acaagtagag gtactgattg aagctctata
     1261 tctacttaca aaagtgaaga tgtgaaaatt tcgttttcat atttctactt attccattct
     1321 atcactaatt gtaaacactt tcaagtgttt tttgaagatt gattgaaaaa atttcataga
     1381 aaacctaggt ttagctcctt gctaccacct tagactaaac aaaaaggagg aaactaagcc
     1441 ctcctaaagt tatagtaaaa tgaaataaga acaggataaa tcgatcagga cagtcaaatc
     1501 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactataggt
     1561 attgttccat tcactaccgt caattttagc acatagtctt catgaaaata ttatatcatc
     1621 acaaccaacc agattctttc gcgatattag ctgcctctgt tcgattacca gcatctagtt
     1681 tcgaaagaat attggtgaca tagttacgga cggttccgtt ggatagataa agtttgtctg
     1741 caatttcttg gttagagaat ccccgagcaa ttccctttaa aacagcaatc tcttgttctg
     1801 tcaacggatt aggatgcgtc atcaccactt ccatcaattc aggcgaatac tccttgcgcc
     1861 cttcgaggac ggtgtgcaag gtttgcatga ggtctgcaat gcttctttct ttcaagacat
     1921 aagcatccac tccagccttg accgcacgtt caaaataccc tggacgcttg aaggtcgtca
     1981 ccacaaccac ctttgtttcg agtttttctg ctcgtatcca ctccaagact tcgaggcccg
     2041 tcttaacagg catttctacg tcaaggatgg cgatatctac agactccttt tctaatagtt
     2101 ggattgcttc ttgcccattc ttggcttgaa agacagactc tacatctggt tgaagcgtga
     2161 gcaactggca catggcatct cgcaacatac tttgatcttc tgcaacaagt agtttcatct
     2221 tagtttctct ccttataagg tagtagaacc tgaacttctg tcggttgttt ccaactaatt
     2281 acctttactt ctcccgaaaa tggaagaaca cgatctcgaa ctgtatggag gtcatccccc
     2341 tttatggaag taaagccaca gccatcatct ctcactgtta gaatgagttc tttctctgtc
     2401 cgttctaatt ttaagtagac tttaaacgct ttagcatgtt tgatgatatt ggtcactaat
     2461 tcgagcaaaa tcatagcagc cgtcgactcc acatcctggg tcaagctagc cttgtctaag
     2521 tgattctcaa cttgaacctc aattccagca atttctaaca tctttttcac agtctctagt
     2581 tcggatgtca aagttctaga cttaagattt tccacaatgg ttcgcacttc attcatggaa
     2641 tccttgctga tctggtgaat ttcttttaat tccttttcca cctgtggata agcctccatc
     2701 tgaaataact gcaaggctag atcagtttta acactaagca tagcaaaggt atgccccaga
     2761 ctatcatgca aatcttgacc gatacgattg cgttcatttt cagcaagcaa tagatttatc
     2821 tgggcatttt gcttagcctg tgcttctttc aaatcctcca caattcgaat ccgaaccaag
     2881 ccaaaagtca ttaaatcgac aaaagcaaga attacaagta gatagaatag aaactcaact
     2941 tcgattctct gaaaaatcaa cagttgaccc acaacaagga cttgagcaag aagaaaagtc
     3001 cagacatgta aagactttaa accacctacg ctgaaatgat agcttaagag attggatagg
     3061 aaaaagaaaa accagatata attaacagcc acaaaggcag tattcccaac tacataagtc
     3121 agcaggatgc cccaatatag ccaagataga cgctggctct tagttgttaa aacacccaaa
     3181 tacgccacta caaatagaat atcaatcaat aaatgccagg cagaaagcaa cccagtcact
     3241 acaggtagga tggggaaaac cataaaaatt aaactgatcc aaaacatata atgtatgctt
     3301 ttcagtcttt caagcattaa gcattctcct tatgaccttg aaggtaaatg gtcaaaccaa
     3361 acaaaactac tgaaaaaaca agtaaataaa ctgtggctga tagattgatt ccaccttcat
     3421 ttaagaaggt cttgattaat tccatcaact gatatgttgg aagacactta cccactactt
     3481 gcatccagtc tggaaataaa gagataggca tccaaagtcc acctaaaaca gccaatccta
     3541 gataaagaag attacccacg acagacatca gctgactagt cggtaagaga gtcaaggtca
     3601 agccaagcgc tacaaaagca atacttccca caatcagcaa aatcgcagct ccaacccagc
     3661 ttgctagaga catgtccaca cctcttacaa aatgcccaac tgagaaaacc accaagattg
     3721 aaaccaaata atcaaccagc atacttgtta tctttgatag ataatattct accatattta
     3781 cagggctatg acgtaatgtt ttctgccagt tgttcatctt gtcggtatgt aaaacaactg
     3841 gaaatgagaa gatagctgtc gacatcatag aaaaggcagt catggagata agataatcac
     3901 gcataaaatt cgcgggtcca cctggtgtat cctggtacat gctagaaaag aatagataga
     3961 aggctgtcgg catccctact gataataaat aatagactga ttgccgtttg gtcaatagaa
     4021 attctatctt atttaatgct atccatcgtt tcatcttagt tatctccctt ctgcgtctct
     4081 tcaaagattg tattcaacaa actacgatta ttaacttcga tttcttgcat cctacatcct
     4141 gcttgggcta atagttccca gaaagcatct gcttctcgag tgactacttg taaagaatct
     4201 tgctttaggg tccagttttc aaccaaattt gactgctcta cgacttcctt gtaagctata
     4261 ggaaggataa agtgcttttc tatttcctcg ctacgcatag ctagaggcgt cgtatctcga
     4321 atcaactctc ccttatttaa gagcaaaatg cggtctgcag tgtgttccac ttcctcaata
     4381 taatgggacg aatagagaat ggtgactcct tgcgctttta actcctggac aatttcccaa
     4441 aaacgttgac gagttgaggt atccatggac gcagtaggct catctaaaaa aacaatcttt
     4501 ggtcgcccaa ttaaggtcaa gacgaaagaa aagagacgct tttgaccgcc tgataatttt
     4561 tctgccaact gttctttttg ttgcttgaca aactgcaata gttgatcaat ttcctgattg
     4621 ctcaaaggat ttggatagat acgttgaaag aaagcaatca actctttaac ttttaatttc
     4681 tgaacgatta cattttcttg agggaggtaa gccctagtat agtctaactt agaactcgtc
     4741 actggtaaac cttgaataga tacttgaccg cttgtgacca gtttatctcc aagcaaacaa
     4801 tctaagagtg ttgtctttcc ggcaccattt ggaccaatta aggcaacaca ttcaccatcg
     4861 ttgatttcaa aggagatatt ccgcaaaatt tccttgtctt ttattttctt actcaatttc
     4921 tcaactttaa ccaccgtcat gagactctcc tttcaaccac tccattccca taaggaaaac
     4981 gacgaaaatc ataaatccaa accccaaagc accacgaatg aattggcgaa gcaaggcttg
     5041 atcaaaccaa tcagtaaaca tttccactaa ccataccaag agtgacaggc cgataaagaa
     5101 atagatgatc cctctcttca ttcctcaaac tcctttttca catctctgac taatttcaaa
     5161 ccttctctaa caagccaaga catgattcca aagccagcaa agaccttcca aggaaaatgg
     5221 tagaaatcct catccaatcc cgaaaacatg agataggtca taactcctgc tactactaaa
     5281 cttactgcga taatcatttt atttctcatc tcttcttccc ccatttcata ctacaattat
     5341 agtcttttaa aatcagagga ggcagaagct tctgtcacta gaaaatatga caaatgtcat
     5401 aaaaaattct gttcaaaaca agcaagatac actatacaat aaaacacaat cagaaaaatc
     5461 taaggcaact tcctcaaaag agatatcaaa cccaattcac accataatgt aaactaatac
     5521 ttatttaaaa tcaaaaagag tagaaatttt tatcagacaa acacatatat agtgtattga
     5581 atctataaca gtagggctta aatactaaaa tatttctata aattaattta actttcctga
     5641 tagagctgtt catatcttat ttcaattctc tatattatac gttgaacaaa acccttctat
     5701 tgctttctta aaaatttata agagttataa aatctgttaa atttcaatgt gtatacctaa
     5761 actacggtat ttattgaaaa gactggggac aaaaagtata cgctgccaaa atgaattact
     5821 gaaaatcaaa aaagagagaa ccaaactgat tccctcttaa tgtatataat atctagtttt
     5881 aaaaatacac actcacatat ctctgt
//
LOCUS       DBEJJE010000076         5052 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEJJE010000076 DBEJJE010000000
VERSION     DBEJJE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.76"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            185..1730
                     /locus_tag="ACL3F5_001953"
     rRNA            185..1730
                     /locus_tag="ACL3F5_001953"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="ACL3F5_001954"
     tRNA            1782..1854
                     /locus_tag="ACL3F5_001954"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..4880
                     /locus_tag="ACL3F5_001955"
     rRNA            1979..4880
                     /locus_tag="ACL3F5_001955"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4957..>5052
                     /gene="rrf"
                     /locus_tag="ACL3F5_001956"
     rRNA            4957..>5052
                     /gene="rrf"
                     /locus_tag="ACL3F5_001956"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1423 a         1026 c         1485 g         1118 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag tgagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttactta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta acggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgctc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 catttagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacccac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat agaagaatga tttgggaaga tcagccaaag agagtaatag
     2341 cctcgtattt aaaatagtct ttgtacttag cagtatcctg agtacggcgg gacacgtgaa
     2401 atcccgtcgg aatctgggag gaccatctcc caaccctaaa tactccctag tgaccgatag
     2461 tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg aggggagtga aatagaacct
     2521 gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg tgagagcgtg ccttttgtag
     2581 aatgaaccgg cgagttacgt tatgatgcga ggttaagttg aagagacgga gccgtaggga
     2641 aaccgagtct gaatagggcg ccttagtatc atgacgtaga cccgaaacca tgtgacctac
     2701 ccatgagcag gttgaaggtg cggtaagacg cactggagga ccgaaccagg gcacgttgaa
     2761 aagtgcttgg atgacttgtg ggtagcggag aaattccaaa cgaacttgga gatagctggt
     2821 tctctccgaa atagctttag ggctagcgtc gacattagag attcttggag gtagagcact
     2881 gtttgggtga ggggtccatc ccggattacc aatctcagat aaactccgaa tgccaatgaa
     2941 ttatggtcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     3001 accaccagct aaggtcccaa aataattgtt aagtggaaaa ggatgtgggg ttgcacagac
     3061 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     3121 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa tttaccgaag ctgtggatac
     3181 ctttataggt atggtaggag agcgttctat gtgtgatgaa ggtataccgt gaggagtgct
     3241 ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa gacaggtgag aatcctgtcc
     3301 accgtaagac taaggtttcc aggggaaggc tcgtccgccc tgggttagtc gggacctaag
     3361 gagagaccga aaggtgtatc cgatggacaa caggttgata ttcctgtact agagtatgta
     3421 gtgatggagg gacgcagtag gctaactaaa gcagacgatt ggaagagtct gtctaagcag
     3481 tgaggtgtga attgagtcaa atgcttaatt ctataacatt gagctgtgat ggggagcgaa
     3541 gtttagtagc gaagttagtg acgtcacact gccaagaaaa gcttctagcg tttaaacata
     3601 ctctacccgt accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga
     3661 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     3721 ttaaagtcag ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc
     3781 taaatcgtaa gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag
     3841 tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac
     3901 ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg
     3961 atttgggcac tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt
     4021 tacccgcgac aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct
     4081 gtaccacatg tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga
     4141 cgctgttggg atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc
     4201 ggagacagtg tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg
     4261 cgcccaaagg ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga
     4321 gcttgactgc gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg
     4381 ttccgtatgg aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat
     4441 ctcccccaag agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc
     4501 ctggggctgt agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct
     4561 gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag
     4621 aggatctgct cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct
     4681 tgccaaaggc atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt
     4741 gtgaaaccca cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga
     4801 tgatcaggta gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa
     4861 tagctcgagg acttatccaa agtaactgag aatatgaaag cgaacggttt tcttgaattg
     4921 aatagatatt caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat
     4981 acacctgtac ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg
     5041 ttgccccctg tg
//
LOCUS       DBEJJE010000077         4119 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEJJE010000077 DBEJJE010000000
VERSION     DBEJJE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.77"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(311..508)
                     /locus_tag="ACL3F5_001957"
     CDS             complement(311..508)
                     /locus_tag="ACL3F5_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515698.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(493..711)
                     /locus_tag="ACL3F5_001958"
     CDS             complement(493..711)
                     /locus_tag="ACL3F5_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0515699.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(809..1594)
                     /locus_tag="ACL3F5_001959"
     CDS             complement(809..1594)
                     /locus_tag="ACL3F5_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515700.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1596..2414)
                     /locus_tag="ACL3F5_001960"
     CDS             complement(1596..2414)
                     /locus_tag="ACL3F5_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515701.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2416..3408)
                     /locus_tag="ACL3F5_001961"
     CDS             complement(2416..3408)
                     /locus_tag="ACL3F5_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515702.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(3793..>4119)
                     /locus_tag="ACL3F5_001962"
     CDS             complement(3793..>4119)
                     /locus_tag="ACL3F5_001962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515703.1"
                     /translation="IMVSNLHQNDKINQLISDYKQNMKAFYITIEKFIRDDESLKCYF
                     IKVISSRSKVTSLDQIEADKTIQRKYSSELKNLLDFIMRLFVREIVSYMYERGGRVGL
                     GSRCVS"
BASE COUNT         1377 a          902 c          698 g         1142 t
ORIGIN      
        1 agtccaaaac tttcgttaac cgggatacat tataagcaca ttcataccat caaaaatagt
       61 agcaataaac ttgaacaact accagaaaca cgaaaacagg cataattgat gaaatatcag
      121 cgctattaaa caatataaat aaccgctaag aataaggctt aacggttatc ttctacctat
      181 ctattttttc aactcctcag tcgtttatct acctataacc taggctttac gagtgccttg
      241 ctctaccaac tgagctaaat cggcgattac acttacagta tagcactctg agaatagatg
      301 tcaagtaata ttattcaagc tttttaatca aaatctgaca aggattttgc ggattccata
      361 gctgagaaaa aatctctaac tttttaaagc caagacctcg ataaaagtca tttgttcgat
      421 cataatcttt attagaacct tctgccactg ttttgacctg cagataacca acttttttac
      481 gagcttcact ctctaaagta gcaagcaatt ggctcccaat ttttctacct tgataagctt
      541 ttttacgccg agacaatcaa tctctgcaca atcttcactc gaataggata accttacaaa
      601 tccagtcaaa tcactctcct gataggcggt ccaaacttgc agtgtcgtgg ttccttctat
      661 ataggcttgt gtgctttctg ggattccaaa ccattctggc aaatccttca aaacctcagc
      721 gacaactgcc ttttttgatt ttcatccttg acttcttcaa ttacaaacat cataagttcc
      781 tttcttgatt ttagtcttac tttagctttt acgaacccgc actttcgtag gaatctaagc
      841 ccttatccca aagtttaagg gaaataacaa agaaaaccag agaaatcaac atcaaacctc
      901 ctacgttaaa gaacacatcc ttttcctgta agaaatagct agctggatag taggctgtaa
      961 aggcgaaagg cacgataaag ctaatcaacc aacgaagaag agaattgtaa atagaaatcg
     1021 gatacttagc aaagtcattg aacatataga agatgtaaat catggcgcct gactgcttag
     1081 tccaaaaggc gatactggct gttgcgattt taagagaagt ataaatcaag gtcgcaaaag
     1141 gaatacaaac taggaaaagc aggaattttg gaagagtcca aacaatgctg gtcactgttg
     1201 ttcccaataa aataccaccg actaagagtt cacccaaggc atcaatctga aaggtttcaa
     1261 ctaggatatg aaagagagga ttgatgggac gagtcagata cttgtcaaac tccccttttc
     1321 ggactaggcg ttgccctagt gcccagagat tgtcaaaaaa gagatggtcc attcccttgg
     1381 gaatcaagga aaatccataa atgaaagcta tctcttgaaa ggtccagcct tctaggaatg
     1441 gaatatgttg aaagatgaca ttgagaaaca agagattcaa gccttgagcc agaaagactc
     1501 ccaagacacc aaccacaaaa tccaccttat attccatgat ttgtttgatg tattgtctga
     1561 taaaaatcag atgcattcgt tgatattttt tcatactaac ctccttgaat ggtgataaag
     1621 gactggaccc gtttccaaat caactgagac aatcccacca tcactaagag ccagaagaac
     1681 tgcaaaagga gtgcctgaag aatctgactg gcatcgtatt ttccaacaat gatcataact
     1741 ggagtataaa tcaaggatga aaaaggcaaa aaggagagaa tatctgaaac aacctttgga
     1801 aagaatgcca agggaatcaa actccccgac ataaaagcca ctatggaagt cttaagtagg
     1861 ttggaacccc aaagattttt aaacacaaag gctgaaaatc caaagcaaat attaaagaaa
     1921 aagttaatca gataggcgag cgttaagcta aaaagataaa tgacagttaa tcctagcacc
     1981 tctacaatac cttgacccga tatgattttc atcaagacaa tgacacttaa aaatggaagg
     2041 ccaacgctga taaaaatcaa ccacttggaa ccaagctcgg tgaaaagata ggaggccgca
     2101 aaatgcactg gtcgcaacaa acgcatgata atggagccat ccttgacctc ctccccaatc
     2161 ataaaggacg aatcggatct agtcagaaga ttggtcacaa aactcatgat gatgtagagg
     2221 gtgatatccg ccatactgaa gccctgaatc aaagactctt gcgaagaatc aaagacagcc
     2281 ttccagagat aaaaggccac aaaagccccc atgacatcgc caatccgata gagaataaag
     2341 ttgactcggt aagtaatcaa ctcctgaacc cctgcattga taaagggttt ataacgtctc
     2401 cacaatttga tcatcctaga gctcctttcg gtagaagcga cggataatat cctcaatatc
     2461 cgtatccacc atcttcaaat cgcggatttc aaaatcagac agggtttgct tgataatgtc
     2521 agctgactgg tagcgagaac tatcaaattc aatgttgagg ctgtttcctt gtctatcaat
     2581 ggtcatatca gacagaccgt catagtgaga gacgagatga ctttgacctg gtagcagttc
     2641 aaaagagaga gtcttcatct taccaaaggt ctccttgagt tggctcaccg ttccatcaaa
     2701 aatctcttgc cccttgtcaa tcatgaaaat ccgatcacaa agttgctcaa tatcactcaa
     2761 atcgtgagtg gtcaaaagaa tggtagtttc ttcctcttga ttgatctgag taattgcccg
     2821 acgaatatta tccttaaccg aaacgtccaa accaatggtc ggctcatcta aaaaaagaac
     2881 cttgggattg tggagcaagg aggccgcaat atccgcccgc atccgttgtc ccagtgaaag
     2941 agtccgcacg ggatccttga taaagtcctt caaatccaag acttcattca aaaagtccat
     3001 acgcttatga aagagcgagt ctggcacatc ataaatctct tttaagacag tgtaggtctc
     3061 ttgcagagcc aaatcccacc atagctgggt gcgttgtcca aagactacgc caatatcttt
     3121 gacataatct tgccgattgt cctggggaat cttgccgtta atccgacaaa aaccagatgt
     3181 tggtttcaaa attcctgtca gcattttaat ggttgtcgac ttcccagcac catttgcccc
     3241 gataaatcct aaaatctgcc cttttggaac ctcaaaggtc aaatccttga ccgcttcaaa
     3301 ggtctgcttt tcaggatgaa taaaggagcg caaagccccc ttcaagcccg gttccttaac
     3361 agtcttcaca aaatttttct gaagatgttc cacttctatc attgccatat ctatctccct
     3421 atcgtaagga atagcaacat tgtgttttta actacaaata ttctaaatcc ttactttcta
     3481 caccttctac attttattac tacagaaggc tttataccaa cctattatag tccaataaaa
     3541 aacaaaatgc aagcgtttgc ctatggattg tgaaattagg atttctctca tgaaataata
     3601 cttttaatca aaaattctgt ttaatagttt aaattaccaa cctactcatc ttctcaccag
     3661 agggcggtat taactttgct cataaaatcg gatactccct ctatccagaa aatatgctca
     3721 gaatgattgt ctctaaacaa tacctgctct tttacctcat tcatgaaaaa gaagtccata
     3781 ccctgagaat tatcaactca cgcaccgact acctaaacca actcgaccac ctctttcgta
     3841 catgtaggaa actatttccc tcacaaataa tctcattata aaatccaata aattttttag
     3901 ctcacttgaa tattttcttt gtatcgtttt atcagcttca atctgatcta gacttgttac
     3961 cttggaacga cttgaaataa cctttataaa ataacactta agactttcat catctcgtat
     4021 aaatttttca atagtgatat aaaaagcttt catattctgt ttgtaatcag atattaattg
     4081 attaatttta tcattctgat gaagattcga taccataat
//
LOCUS       DBEJJE010000078         4060 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEJJE010000078 DBEJJE010000000
VERSION     DBEJJE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.78"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(173..1588)
                     /locus_tag="ACL3F5_001963"
     CDS             complement(173..1588)
                     /locus_tag="ACL3F5_001963"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0515704.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLGLPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLEYS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="ACL3F5_001964"
     CDS             complement(1601..3439)
                     /locus_tag="ACL3F5_001964"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0515705.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..>4060)
                     /locus_tag="ACL3F5_001965"
     CDS             complement(3457..>4060)
                     /locus_tag="ACL3F5_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0515706.1"
                     /translation="LGKITLGNNFDEIIYINLTDHISSSIERYKEGVIISNPLRWEIS
                     KYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHFVNANLENNFQESYKITEIIMG
                     IEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPR
                     EYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT         1360 a          808 c          533 g         1359 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 ttcaatgaga tgttgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagttg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa tactctaaat
      601 aaggatttac taagccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacggta taatttttta
      721 ataattttgc atcttcagct gcaaactcta tgttaatgtc atgttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaatcc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggctctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcttca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc taacaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 atcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggga taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccaactt caacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaatg accgccacaa
     2161 ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tatgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggtccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaatagc tggtgttaat ttagcaatta
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gatgaaccat
     2821 aactagctgg tgtcacaggt gcaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaatgattac caagactttc aacatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccgtatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactccgt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctaga
//
LOCUS       DBEJJE010000079         3984 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEJJE010000079 DBEJJE010000000
VERSION     DBEJJE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.79"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..205)
                     /locus_tag="ACL3F5_001966"
     CDS             complement(<1..205)
                     /locus_tag="ACL3F5_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515707.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELF"
     gene            complement(198..926)
                     /locus_tag="ACL3F5_001967"
     CDS             complement(198..926)
                     /locus_tag="ACL3F5_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515708.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(960..1130)
                     /locus_tag="ACL3F5_001968"
     CDS             complement(960..1130)
                     /locus_tag="ACL3F5_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515709.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(1143..2954)
                     /locus_tag="ACL3F5_001969"
     CDS             complement(1143..2954)
                     /locus_tag="ACL3F5_001969"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0515710.1"
                     /translation="MDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWI
                     RVFSSFSKVKGRLILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSL
                     LCLYLISILARSMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLS
                     GFRELFTNQVVGGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYD
                     TVNRELQEQSLIYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHI
                     LYNSATNVFQLFAPIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQ
                     YILAAGYLNRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLT
                     IEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVP
                     QDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISG
                     GQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIK
                     DADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            complement(2954..3286)
                     /locus_tag="ACL3F5_001970"
     CDS             complement(2954..3286)
                     /locus_tag="ACL3F5_001970"
                     /inference="COORDINATES: protein motif:HMM:NF015377.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0515711.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTDSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIKRIRSI"
     gene            complement(3297..3827)
                     /locus_tag="ACL3F5_001971"
     CDS             complement(3297..3827)
                     /locus_tag="ACL3F5_001971"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0515712.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHDSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVYYWS"
     gene            complement(3908..3970)
                     /locus_tag="ACL3F5_001972"
     CDS             complement(3908..3970)
                     /locus_tag="ACL3F5_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGR0515713.1"
                     /translation="MKKISKFLPILVLVMDIIII"
BASE COUNT         1392 a          696 c          437 g         1459 t
ORIGIN      
        1 aaaatagttc agaaaaataa aatattgttt gttctttaaa aattaactgc caattagata
       61 aagcaagttc attttgatgc accaataaat aacctcgata cctaaaagtt aagtctatat
      121 ataacaaagc attcagaatt attggaaaaa taagaacaaa ccataagatg ctttttttct
      181 gctttagaaa ctctaattta atcatattca cctccagcta aacaagctaa gtaggcttct
      241 tccagatttc gacaattata cttttgtaaa aggtagtggc aagaaccaaa aaattcaact
      301 ttcccataat ttataattat aatatcagat atcactttat ccagttcact aagaatatga
      361 cttgatatta aaaatgtaat accttttttc tcctgtagaa aacggattaa acttctaatt
      421 tcaattacac cctgtggatc aagtccattg attggttcat cccaaattaa tatttctgga
      481 ctacctaaca atgatgcagc tatacttaga cgttgtttca tgcccattga aaaatttttc
      541 acttttttct ttttaacatc ttttaatcct accattgata gatattcatt aagtctttca
      601 gtatctaaac taagcccttt catatttgct attaacttca aatttttata agcatcaaga
      661 tgaccataaa atgaaggtcc caaaactaat cctatcctag ataatatatt ttcggaattc
      721 tgttctacgg tttgattaaa aatagttatt ttcccagaat ctggttttaa aatccctaga
      781 atcattttga taattgtagt ttttccagcc ccatttggtc caacaaaacc atatactttt
      841 cccttattta aataaaatga agtgttatga ataacttcaa tatctttaaa gctttttgtt
      901 agatttataa tttcaactat agccatctct actccttagt ttacagcaaa aaattatgct
      961 taattcttat tgtttttgta aaaaatcagc gaacctaata ctattccatt caacaaacct
     1021 aaagaaatac catattcaac tggaaaatct aaaaaaattg caaatactat tccaatcatc
     1081 acccctagtg aggctgctgt tgaaattaca tattcattta ctttcttcat tttctttaca
     1141 cctcatttcc tttttgtata taagctgtag tactctccac caagatccat taagtactta
     1201 tgatttcctg actcaacaat cttaccacct ttcattacaa aaataatatc cgcatcctta
     1261 atcgttgaca atctatgagc tataattatt tgagtacaac cctgactttg tatatacttt
     1321 gttattcttt cctcattaat agtgtctaat gcactagttg cttcatctaa aattacaata
     1381 ctaggattat ttattaatgc acgtgccagt gctatccgtt gcctttgccc acctgaaata
     1441 tttgacccca tctctgagat gatagtatta aatttcatcg gcatagccat gatttcatca
     1501 tagatttgaa ctgctttaca aacttcctct atcttttgtg aagtaacttc gttctttaaa
     1561 gttatattat caagaatact tcggttcaat aaaaatgaat cctgtggaac tactcctaaa
     1621 ttttgactta atattttttt atctatttga ttaatattta caccatcaaa taaaactttt
     1681 cctgtatcaa tcttatataa tcctgatagt atttttgata acgtactttt tcctgacccc
     1741 gattgaccga ctagtgcaat tctctgtcct ggctcaatag tcaaatttaa attttctatt
     1801 acaggagctg agtctttgga ataagagaaa gataggtcct taatatctat tctaccttct
     1861 aaagaacact ttttaagacc attttcaaca ttctcttcat tttcaagcca gatatcattt
     1921 actctattta agtatcctgc tgccaaaata tactgcgtat aagcattaaa tattgagatt
     1981 tctgaactaa ataaaattga tgccatggtt tgaaatgcga caacctcacc caataaaatt
     2041 tttccattta aaacattatc aagtccaaaa atcaatataa ttataggagc gaacaattga
     2101 aatacattag tagctgaatt gtataaaata tgcacaatac ttcgtttttt atactttgtc
     2161 aatacgtttt ttaaatactt agaccagttt tcatatattt catcttctaa tcccgatatt
     2221 tttattgaag aaatagtatt taatgcttct gtttctactg agtaaatcaa tgattgttct
     2281 tgtaattctc tattaaccgt atcatacatt atttttctag tactaaacag aaacaaaaaa
     2341 ttaattaaac tcaatataag agctataatt gataatgttt ttgaactaag aaacatatat
     2401 attacaacac ttagaatagt cccgatatct actactcccc caacaacttg gttagtaaat
     2461 agctccctaa aaccactaag actagaaatt ctgtataaaa tatctccttt tgccctgagt
     2521 tcaaaaaaac tatatggtag tttaagcaaa tgcttaaatg taaaactttc aatatctcta
     2581 ctaaaaaata tattagaaaa tagaattccc atactcctag ccaagataga aataaggtac
     2641 aaacaaagta gagaaaataa aattaaaaac gaggtttgaa aagaaaatgt attccctaat
     2701 gcagaattaa taaactttga agtcattact ggtacggaaa gtattattaa gtaacttatt
     2761 attgaaaata gtaacgtcaa aatcaatcga ccttttacct ttgaaaaact agagaatact
     2821 cttatccatg gagaaggaaa ctgcgacttc aaagattgat aattttcgtt aggaaatgat
     2881 agcagtacta tattactaaa atgttttgaa aactccttaa actcataatt tatatatcct
     2941 ttagaaggat ccattatata gaccttattc tttttatata gaccttattc ttttttactt
     3001 tgtaaataac tacataatgt tgattatccc agaatgctat taatggtaac ggaagttcac
     3061 taattttatt tacatcttta acttgatatg agtcagtatc aaaatttcgt ttattcaata
     3121 actgtttcaa gtcacctata ctataaccat ctctcccttt ttctatatca cgtcttaaat
     3181 ctagtaatgt ctctttgctt ttatagaaat gtagtatgga caagcagcaa cataaaccac
     3241 attctatttg agacatttgc tcaatattag gtacttttct agtcatcatg tcctctttaa
     3301 ctccagtaat aaacattaag taatctatca tcttgttttc gagatatttc atagacaact
     3361 ccagatactc ctagcataaa agaaaatgta ttcatagtat tcaaatccgt acttaattct
     3421 ggtttgataa cctgagaaac gacattatca aaataaaaat ctatagattc ttttattaat
     3481 aggttttctt catctttcaa tattgcatca agacaactga tagtacctac agaatcgtga
     3541 cataaattca attctcttat tttttctaca ttagttaata cattttcaat tattgataaa
     3601 tcattattcc caatattagt tttatcgaaa atttcttttc tagctaataa aatgcccgga
     3661 gctccataac accaaaaatt aggaaaggaa tcattatgat ttcttcttat gtctttccaa
     3721 ttttttaata tattattgaa acatttatct tctttatata gtaattcctc tatacatttt
     3781 aatatatctg tactaggatt aatttcataa taatatgata atgacattgc tactccagaa
     3841 taaccgtgtg ttaaacctgt tactgttata ttatctaatt gtgaaataca ataattaata
     3901 cactttttta aatgatgata atatccatca ccaaaaccaa aatcggtaaa aattttgaaa
     3961 ttttcttcat acttggactt cctt
//
LOCUS       DBEJJE010000080         3908 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEJJE010000080 DBEJJE010000000
VERSION     DBEJJE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.80"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            210..737
                     /locus_tag="ACL3F5_001973"
     CDS             210..737
                     /locus_tag="ACL3F5_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0515714.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIISLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            814..1170
                     /gene="glnR"
                     /locus_tag="ACL3F5_001974"
     CDS             814..1170
                     /gene="glnR"
                     /locus_tag="ACL3F5_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0515715.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            1207..2553
                     /gene="glnA"
                     /locus_tag="ACL3F5_001975"
     CDS             1207..2553
                     /gene="glnA"
                     /locus_tag="ACL3F5_001975"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0515716.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2649..2768)
                     /locus_tag="ACL3F5_001976"
     CDS             complement(2649..2768)
                     /locus_tag="ACL3F5_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0515717.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            2733..2882
                     /locus_tag="ACL3F5_001977"
     CDS             2733..2882
                     /locus_tag="ACL3F5_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0515718.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            3256..3908
                     /locus_tag="ACL3F5_001978"
                     /pseudo
     CDS             3256..3908
                     /locus_tag="ACL3F5_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         1246 a          665 c          762 g         1235 t
ORIGIN      
        1 ggttttgtcg cttttcatta taggtcatat gggacttttt ttctacaata aaataggctc
       61 cataatatct atagtggatt tacccactac aaatattata gagcctgaaa gttcctcttt
      121 tcttttgctt aaaataaaaa cgcttcctct caactattac tcataaaaat caccgattta
      181 tgataaaatg gaaatagaaa gttgagatta tgagttattt taaaaaatat aaattcgata
      241 aatcccagtt caaacttggt atgcgaacct ttaaaacagg tattgctgtt tttctagttc
      301 tcttgatttt tggctttttt ggctggaaag gtcttcaaat tggtgctttg acagccgttt
      361 ttagcctgag ggagagtttt gatgagagtg ttcattttgg gacttcgcgt attctaggaa
      421 atagtatcgg tggactctat gccttggtct tcttcttatt aaataccttt ttccatgaag
      481 ccttttgggt gaccttggta gttgttccaa tctgcaccat gttaaccatt atgacaaatg
      541 tagccatgaa taacaaagca ggggttattg gtggtgtagc agctatgtta atcattagcc
      601 tatcaattcc aagtggtgag acaatttcgt acgtgtttgt acgtgtatca gaaacgttta
      661 tgggagtttt tgtcgcaatt atcgtaaatt acgatattga tcgtattcgt ctctttttag
      721 agaaaaaaga aaaataatgt tacattttat aacattatca attgacgttt gtcttttttt
      781 agactataat agacagaaag aaggaaattg taaatgaagg aaaaagaatt tcgccgaaat
      841 atggctgttt ttcctatcgg cagtgttatg aagttgaccg atctatcggc gcgtcagatt
      901 cgttattatg aagatcaaga gttgatcaag cccgatcgaa acgaaggaaa tcgtcgcatg
      961 tattccttga atgacatgga tcgtctgctt gaaatcaaag attatatctc tgaaggttat
     1021 aatatcgctg ccattaagaa aaaatatgct gaacgtgaag cgaaatccaa gaaagcggtt
     1081 agtcagactg aagtacgtcg tgcacttcac aatgaactcc tccaacaggg gcgttttgct
     1141 tcagtacagt caccttttgg tcgcggttag gcaaccgcaa gtagtcatag attaaggaga
     1201 aaacttatgc caatcacagc tgcagatatt cgtcgtgaag tcaaggaaaa aaatgttacc
     1261 tttattcgtc ttatgttctc agatattttg ggaaccatga aaaacgtcga aattcctgct
     1321 acagatgaac agttagataa ggtcttgtcg aacaaggtta tgtttgatgg atcttctatt
     1381 gaaggttttg tacgtatcaa tgagtcggat atgtacttgt acccggactt ggatacatgg
     1441 acagtcttcc cttggggaga tgaaaatgga agtgttgcag gtctgatctg tgatgtctat
     1501 acaacagaag gtgaaccatt tgcgggtgac cctcgtggta atttgaaacg agctcttcgt
     1561 cacatggaag aagttggatt caaatccttc aaccttggtc cagagccaga attcttccta
     1621 tttaagttgg atgaaaatgg ggacccaaca cttgaagtga atgacaaggg tggctacttt
     1681 gatttggcac ctactgacct tgcggacaac acacgtcgtg agattgtgaa tgtcttgacc
     1741 aaaatgggat ttgaagtaga agcgagtcac cacgaggttg cggttggaca gcatgagatt
     1801 gactttaagt acgatgaagt tctccgtgct tgtgataaga ttcaaatctt taagcttgtt
     1861 gttaaaacca ttgctcgcaa acacggactt tacgcaacat ttatggcgaa gccaaaattt
     1921 ggtattgctg gatcaggtat gcactgtaat atgtccttgt ttgatgcaga aggaaataac
     1981 gccttctttg atccaaatga tccaaaagga atgcagttgt cagaaacagc ttaccatttc
     2041 ctaggcggtt tgatcaagca tgcttacaac tatactgcca tcatgaaccc aacagttaac
     2101 tcatacaaac gtttggttcc aggttatgaa gcgcctgttt acattgcttg ggctggtcgt
     2161 aaccgttcgc cacttgtgcg cgtacctgct tcacgtggta tgggaactcg tcttgagttg
     2221 cgttcagtgg atccaatggc gaacccttac gttgctatgg ctgttctttt ggaagttggt
     2281 ttgtatggta ttgaaaataa aatcgaagca ccagctccta tcgaagaaaa tatctacatc
     2341 atgacagcag aagagcgcaa ggaagctggt attacagacc ttccatcaac tcttcacaac
     2401 gctttgaaag ctttgacaga agatgaagtg gttaaagctg ctctcggaga tcacatctat
     2461 actagcttcc ttgaagccaa acgaatcgaa tgggcaagtt atgcaacctt cgtttcacaa
     2521 tgggaaattg ataattattt agacctttac taatactaat atagaagaaa gattgcctgt
     2581 gggtaaacag tcacacagca gtctaagcca tcaaatacct ataaccctta aaatagcgat
     2641 ttcggtcgct atttattttt cgaaaaatcc tcttgactct tttgcgaatt agatttatca
     2701 tcagacgtgt agaagaaaat taaggagtca ctatggaaaa attcaatttc aaaaacaata
     2761 tcgggcaaga aaacaagtta cttcaaatcg aaatctacaa gtttactaac ttttgcaagc
     2821 ttcaaaatta cacatctgta aatatttttt cgaaagatat atttgaagcc atagtaaatt
     2881 gagactagaa tagtacacta catctgctaa aaatttctag aaactaattt aactttccta
     2941 atcgatttgt ttacatctta tttcaatcta ctatattatc tcaataaatg atgatggcga
     3001 ctgttttgtt tgtgcttgtc gatttttgaa tcctgatcga gcggaagaat atttctgccg
     3061 aggttgtcaa ggggaaaatc ctgaagatat tgaattttat gatgaacaat tacaggcaga
     3121 aaaggtggag gctttgaata ttcgattgga agtaaaaaat tgaattatct acaatctcat
     3181 caacaataaa cctatttcaa ccccattatc tataggcgta tttttacgcc tttttatata
     3241 cttgaagcac ataagaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat
     3301 gttccttatg atattcctga tacttgggag tgggtgagga taaaatcaat ttattggaat
     3361 tttgggcaaa ataagccaga gaaatccttt aggtatatag atacgtctag tattgataga
     3421 aaaaagaata taatcaacta caaaaatcta caatatcttt cacctgaaca agcgccttcc
     3481 cgtgctagaa aattagtttc gcagaatagt gtcttatttt caacagttag accatatcta
     3541 aaaaatattg ctgtagttag agaacttaaa gagtatttga tagctagtac agcatttatt
     3601 gttttggata ctttacttaa cgaaacatat ttgaaatatt atttattatc agataatttt
     3661 atcaatcgtg ttaataataa atctactgga acaagttatc ctgcaatcaa tgattataat
     3721 tttaatctat tattaattgc tctcccccca ctatccgaac aacaacgcat aatagaagca
     3781 atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa gttataatag actagaacag
     3841 ctagataaag aatttccaga taaactaaaa aaatctattc ttcaatatgc tatgcaagga
     3901 aaattagt
//
LOCUS       DBEJJE010000081         3804 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.81, whole genome shotgun sequence.
ACCESSION   DBEJJE010000081 DBEJJE010000000
VERSION     DBEJJE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.81"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..378
                     /locus_tag="ACL3F5_001979"
     CDS             <1..378
                     /locus_tag="ACL3F5_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0515719.1"
                     /translation="KEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEA
                     EDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDN
                     NTISAEVDSLLALLKESQPTPIQ"
     gene            588..3707
                     /gene="phtE"
                     /locus_tag="ACL3F5_001980"
     CDS             588..3707
                     /gene="phtE"
                     /locus_tag="ACL3F5_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0515720.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPIKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1422 a          620 c          741 g         1021 t
ORIGIN      
        1 aaggaacatg atgaagtaag tgagccaact caccctgaat ctgatgaaaa agagaatcac
       61 gctggtttaa atccttcagc agataatctt tataaaccaa gcactgatac ggaagagaca
      121 gaggaagaag ctgaagatac tacagatgag gctgaaattc ctcaagtaga gcattctgtt
      181 attaacgcta agatagcaga ggcggaggcc ttgctagaaa aagtaacaga ttctagtatt
      241 agacaaaatg ctgtggagac attgactggt ctaaaaagta gtcttcttct cggaacgaaa
      301 gataataaca ctatttcagc agaagtagat agtctcttgg ctttgttaaa agaaagtcaa
      361 ccgactccta tacagtagta aaatgaatgg agcatatttt atggagaagt aacctttcgt
      421 gttacttctc ttttttagaa aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta
      481 aactatttac tggttaatta aatggttaaa taaccggttt agaaaactat ttaataaagt
      541 aaaagaagtt gagaaaaaac ttcatcattt attgaaatga gggatttatg aaattcagta
      601 aaaaatatat agcagctgga tcagctgtta tcgtatcctt gagtctatgt gcctatgcac
      661 taaaccagca tcgttcgcag gaaaataagg acaataatcg tgtctcttat gtagatggca
      721 gccagtcaag tcagaaaagt gaaaacttga caccagacca ggttagccag aaagaaggaa
      781 ttcaggccga gcaaattgta atcaaaatta cagatcaggg ctatgtaacg tcacacggtg
      841 accactatca ttactataat gggaaagttc cttatgatgc cctctttagt gaagaactct
      901 tgatgaagga tccaaactat caacttaaag acgctgatat tgtcaatgaa gtcaagggtg
      961 gttatatcat caaggtcgat ggaaaatatt atgtctacct gaaagatgca gctcatgctg
     1021 ataatgttcg aactaaagat gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg
     1081 agaaggttaa ctctaatgtt gctgtagcaa ggtctcaggg acgatatacg acaaatgatg
     1141 gttatgtctt taatccagct gatattatcg aagatacggg taatgcttat atcgttcctc
     1201 atggaggtca ctatcactac attcccaaaa gcgatttatc tgctagtgaa ttagcagcag
     1261 ctaaagcaca tctggctgga aaaaatatgc aaccgagtca gttaagctat tcttcaacag
     1321 ctagtgacaa taacacgcaa tctgtagcaa aaggatcaac tagcaagcca gcaaataaat
     1381 ctgaaaatct ccagagtctt ttgaaggaac tctatgattc acctagcgcc caacgttaca
     1441 gtgaatcaga tggcctggtc tttgaccctg ctaagattat cagtcgtaca ccaaatggag
     1501 ttgcgattcc gcatggcgac cattaccact ttattcctta cagcaagctt tctgccttag
     1561 aagaaaagat tgccagaatg gtgcctatca gtggaactgg ttctacagtt tctacaaatg
     1621 caaaacctaa tgaagtagtg tctagtctag gcagtctttc aagcaatcct tcttctttaa
     1681 cgacaagtaa ggagctctct tcagcatctg atggttatat ttttaatcca aaagatatcg
     1741 ttgaagaaac ggctacagct tatattgtaa gacatggtga tcatttccat tacattccaa
     1801 aatcaaatca aattgggcaa ccgactcttc caaacaatag tctagcaaca ccttctccat
     1861 ctcttccaat caatccagga atttcacatg agaaacatga agaagatgga tacggatttg
     1921 atgctaatcg tattatcgct gaagatgaat caggatttat catgagtcac ggtaatcata
     1981 atcattactt cttcaagaag gacttgacag aagagcaaat taaagctgcg caaaaacatt
     2041 tagaggaagt taaaactagt cataatggat tagattcttt gtcatctcat gaacaggatt
     2101 atccaggtaa tgccaaagaa atgaaagatt tagataaaaa aatcgaagaa aaaattgctg
     2161 gcattatgaa acaatatggt gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg
     2221 cgattattta tccgcatgga gatcatcatc atgcagatcc gattgatgaa cataaaccgg
     2281 ttggaattgg tcattctcac agtaactatg aactgtttaa acccgaagaa ggagttgcta
     2341 aaaaagaagg gaataaagtt tatactggag aagaattaac gaatgttgtt aatttgttaa
     2401 aaaatagtac gtttaataat caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt
     2461 ttagttttcc gcctgaattg gagaaaaaat taggtatcaa tatgctagta aaattaataa
     2521 caccagatgg aaaagtattg gagaaagtat ctggtaaagt atttggagaa ggagtaggga
     2581 atattgcaaa ctttgaatta gatcagcctt atttaccagg acaaacattt aagtatacta
     2641 tcgcttcaaa agattatcca gaagtaagtt atgatggtac atttacagtt ccaacctctt
     2701 tagcttacaa aatggccagt caaacgattt tctatccttt ccatgcaggg gatacttatt
     2761 taagagtgaa ccctcaattt gcagtgccta aaggaactga tgctttagtc agagtgtttg
     2821 atgaatttca tggaaatgct tatttagaaa ataactataa agttggtgaa atcaaattac
     2881 cgattccgaa attaaaccaa ggaacaacca gaacggccgg aaataaaatt cctgtaacct
     2941 tcatggcaaa tgcttatttg gacaatcaat cgacttatat tgtggaagta cctatcttgg
     3001 aaaaagaaaa tcaaactgat aaaccaagta ttctaccaca atttaaaagg aataaagcac
     3061 aagaaaactc aaaacttgat gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa
     3121 aagaaaaact ttctgaaact gggaatagta ctagtaattc aacgttagaa gaagttccta
     3181 cagtggatcc tgtacaagaa aaagtagcaa aatttgctga aagttatggg atgaagctag
     3241 aaaatgtctt gtttaatatg gacggaacaa ttgaattata tttaccatcg ggagaagtca
     3301 ttaaaaagaa tatggcagat tttacaggag aagcacctca aggaaatggt gaaaataaac
     3361 catctgaaaa tggaaaagta tctactggaa cagttgagaa ccaaccaaca gaaaataaac
     3421 cagcagattc tttaccagag gcaccaaacg aaaaacctat aaaaccagaa aactcaacgg
     3481 ataatggaat gttgaatcca gaagggaatg tggggagtga ccctatgtta gatccagcat
     3541 tagaggaagc tccagcagta gatcctgtac aagaaaaatt agaaaaattt acagctagtt
     3601 acggattagg cttagatagt gttatattca atatggatgg aacgattgaa ttaagattgc
     3661 caagtggaga agtgataaaa aagaatttat ctgatctcat agcgtaagga atagcagtag
     3721 aaaaagtctg aatcaaaaat gaagttctct caaaagttag aaataaaact ctgactttgg
     3781 gagaatttca ttttattatt aata
//
LOCUS       DBEJJE010000082         3475 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.82, whole genome shotgun sequence.
ACCESSION   DBEJJE010000082 DBEJJE010000000
VERSION     DBEJJE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.82"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..300
                     /locus_tag="ACL3F5_001981"
     CDS             <1..300
                     /locus_tag="ACL3F5_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515721.1"
                     /translation="QNRLHNIYKGFTHYKYYRAENSHLIYADYFEMKLKKLLKDDTKV
                     FEKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(658..1191)
                     /locus_tag="ACL3F5_001982"
     CDS             complement(658..1191)
                     /locus_tag="ACL3F5_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0515722.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1280..2056)
                     /gene="recX"
                     /locus_tag="ACL3F5_001983"
     CDS             complement(1280..2056)
                     /gene="recX"
                     /locus_tag="ACL3F5_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0515723.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIIRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2094..3449
                     /gene="rlmD"
                     /locus_tag="ACL3F5_001984"
     CDS             2094..3449
                     /gene="rlmD"
                     /locus_tag="ACL3F5_001984"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0515724.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1147 a          585 c          608 g         1135 t
ORIGIN      
        1 caaaataggc tccataatat ctataaggga tttacccact acaaatatta tagagccgaa
       61 aattcacatc taatatatgc agactacttt gaaatgaaat taaaaaaatt attaaaggat
      121 gacacaaaag tttttgaaaa atctacattc aaatttgtag aaggatataa aatatacctg
      181 acagaatcta aagaatctgg aattaaacaa atggacaatg tcataaaata ttttgagttt
      241 attgaatcta aaagtattgc tttatatttt caaaaacgat taaatgagct gatagattaa
      301 atagcatttt ctctgttgag atattgtttt taaaatattg tactaaatga ttgatgctat
      361 gtggaaatac aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat
      421 tttcgtattt tttgtattaa acgatataag tttgttgtaa acttacaagg aataaagaca
      481 ttaaaaaata atagtatatc tatttgtttt atatatttta cgaattctgc ataaatctct
      541 ttctagtaat gtgttgtaac tctgctataa tggatttatt cctttttgtg tttacacaat
      601 ttattttata ctaccaaaaa aacaaggtca ggattttgtt cctgaccttt gacaacttta
      661 ccgattcttt agttctacat agcgcttgta ccaaatgttt acataggctt ctgagaaagg
      721 accacgtcca ttgttaatcc aatcaacaag aattttgaca tgttctttta aaatatagtc
      781 caagtcatca gaataattca ttttgcgttt gtgacgctcg tactcttcaa cgtccaagag
      841 acgtttttcc ccatctgtaa aaattttaac atccaaatcg taatcaatat acttcagtgc
      901 ttcttcatcc agatagtagg ggctagccat attgcaatag taagaagttc cattatcacg
      961 aatcatggca atgatattaa accaatattt cttgtgaaag taaacaatag ccggttctcg
     1021 agtgacccaa cgacgaccat cactttcggt aacaagtgta tgatcgttga caccaataat
     1081 ggcgttttct gttgttttta gtaccatggt gtcccgccaa gttcggtgga gactcccatc
     1141 atgcttataa ctttgaattg taataaagtc gccttctttt ggaagcttca taactaacca
     1201 actttctaca atttataagt ttatcattta ctattgtacc ataaaattac ctaaaatctg
     1261 tgaatttcac ttggaaatat taaagatatt ctctaagagc gcttgctata tccgaaaaat
     1321 cgtagccctt tcgtgctaaa acttgagtta aacgctgctt cagttcgtat ccttcatact
     1381 ttcgagcata cttactatat tgtttatcaa gttccttgaa gatgagttct tgagtcgttt
     1441 cttggtcaac ttggctatct aagtcgtcaa aggcaatttt agcatcagaa taagagaagc
     1501 ccttgttagt caagttctgg ataatcttat cttgcagggc acgagatgga agttttccct
     1561 catatttttt caatagttta ttagctacac gttgagcaac ttcagaaaaa tcaaattctt
     1621 tcaagttctc ttctatagta gattttgaaa tccctttttg agctagtttc tgagtcagca
     1681 cataaggacc cttgtctcct gaaagttgat tggtattgat gatagcataa gcgtactgac
     1741 catcattaat ccacttatct tctttaagat tagcaataac ttgagaaacg atgtttttat
     1801 caatatcgta ttttttcaga tattctctga cctctttttc agtacgtgct ttaaaggata
     1861 agtggtagag ggccagattc ttaccataag aaaattgagc aaagtcttga atctctttca
     1921 attcctcttc gcttatcacc ttatctctcg ataacataaa acgaataatt gtgtcttcgg
     1981 tgatatagca tttgtcgcca ttatcaagct ccatcagata gagtcttttt ttcttttcaa
     2041 gttttgtgat tttcatagct ctattataac tcaaaatgtg ataagatagg ggtatgaatc
     2101 tgaaagtgaa acaaaaaata ccattaaaaa tcaagcgcat gggaattaac ggtgagggaa
     2161 tcggctttta ccaaaaaaca ttagtctttg taccaggagc tctcaaaggc gaagatatct
     2221 attgtcagat tacttctatt agacgcaact ttgttgaagc aaaattactg aaggtcaaca
     2281 agaagtctaa atttcgaatt gtgccatctt gtactattta taatgaatgc ggaggctgcc
     2341 aaatcatgca cctgcattat gataagcagc tggagttcaa gacggactta cttcatcaag
     2401 cgctgaaaaa atttgctcct gcaggatatg aaaattatga aattcgtcca actattggaa
     2461 tgcaggaacc aaaatattac agagctaagt tacaatttca gactcgaaaa tttaaaaatc
     2521 aggtcaaggc gggcttatat gcacaaaact ctcactattt agtagagttg aaagactgcc
     2581 tggtacaaga taaggaaacc caagtgattg ctaatcgctt agcagaatta cttacttatc
     2641 accagattcc aatcacggat gagagaaaag ttctaggtgt ccgtactatt atggtccgac
     2701 gcgcgagaaa gaccggacag gttcagatta ttattgttac aaaccgccag cttaatttaa
     2761 ctcaattggt aaaagagttg gttaaagatt tcccagaagt tgtgacagta gctgttaata
     2821 caaatacagc taaaaccagt gagatatatg gtgaaaagac agagattatc tgggggcaag
     2881 agagtattca agaaggtgta ctcaattatg aattttcact atcccctcga gctttttatc
     2941 aactaaatcc tgagcaaaca gaagtcctct atagcgaagc agtaaaagcg ctggatgttg
     3001 ataaagaaaa ccatttgatt gacgcttatt gtggagttgg aacgattgga tttgcctttg
     3061 caaagaaagt aaaaacactc agaggtatgg atattattcc agaagctatt gaagatgcca
     3121 agcgaaatgc taaaagaatg ggatttgaca atactcatta tgaagctgga acggcagaag
     3181 agattattcc tcgttggtac aaggaaggct accgagcaga tgctttgatt gttgacccac
     3241 cacgtacagg tctggatgat aagttattag atactattct tacttatgta ccagaaaaaa
     3301 tggtttatat ttcttgtaat gtttcgacct tggctcgtga tttggtacgc ttagtagaag
     3361 tctatgatct tcattatatt cagtcggtcg atatgttccc acatacagct cgaactgaag
     3421 ctgttgtaaa attaataaaa aaagtttaaa aaaggtgttg acaaagtttg aaaag
//
LOCUS       DBEJJE010000083         2945 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.83, whole genome shotgun sequence.
ACCESSION   DBEJJE010000083 DBEJJE010000000
VERSION     DBEJJE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.83"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(85..1026)
                     /locus_tag="ACL3F5_001985"
     CDS             complement(85..1026)
                     /locus_tag="ACL3F5_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0515725.1"
                     /translation="MKQTKRIKRWRYYLCRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL3F5_001986"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL3F5_001986"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0515726.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          857 a          691 c          593 g          804 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg tgaagctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcgtgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accgacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggaattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcacagata atagcgccac cgcttaattc gttttgtttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaagtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tcttgctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaagtagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat gctcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggtt
//
LOCUS       DBEJJE010000084         2853 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.84, whole genome shotgun sequence.
ACCESSION   DBEJJE010000084 DBEJJE010000000
VERSION     DBEJJE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.84"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..981
                     /locus_tag="ACL3F5_001987"
                     /pseudo
     CDS             1..981
                     /locus_tag="ACL3F5_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1115..2391
                     /locus_tag="ACL3F5_001988"
                     /pseudo
     CDS             1115..2391
                     /locus_tag="ACL3F5_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2602..>2853)
                     /locus_tag="ACL3F5_001989"
     CDS             complement(2602..>2853)
                     /locus_tag="ACL3F5_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0515727.1"
                     /translation="VPAQPGTEDKKPSAPKPDMQPSPQPEGKKPSVPEINQEKEKAKL
                     AVATEKKLPSTGVASNLVLEIIGLLGLIGTSFIAMKRRK"
BASE COUNT          965 a          557 c          494 g          837 t
ORIGIN      
        1 gagacctgaa gagaggacag aattagaacg tcttcaatca gaaaatgagt acctgagagc
       61 ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa aagagaaaga
      121 agaaagacag aaattgttca agaattaatg actgagtttt cgttagttct tcttctaaaa
      181 tccattaaac tagctcgttc gacctactac tatcacttga aacagctaga caaaacagat
      241 aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat
      301 gcttatcgcc gggttcattt agaactaaga aatcgtgctt atctggtaaa tcataaaaga
      361 gttcaaggct tgataaaagt actcaattta caagctaaaa tgcgacagaa acgaaaatat
      421 tcttctcata aaggagacgt tggcaagaag gcagagaatc tcattcaagg ccaatttgaa
      481 ggctctaaaa caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagcaagt
      541 actcaaaagc tttacttatc accagtttta gatggcttta acagcgaaat tatcgcctat
      601 aatctttcaa cttcacccaa tttagaacaa gtacaaacaa tgttggaaca gtcattcaca
      661 gagaagcact acgagaatac gattctccat agtgaccaag gctggcaata tcaacacgat
      721 tcttatcatc agtttcttga gggtaaggga attcaagcat ccatttcacg taagggtaac
      781 agcccagaca atggtatgat ggagtccttt tttgggattc tgaaatcgga aatgttttat
      841 ggctatgaga aaacatttaa atcacttaat cgattggaac aagctattgt agactatatt
      901 gattactaca acaataaacg aattaaggta aaactaaaag gacttagccc tgtgcaatac
      961 agaactaaat ccttcggata aattaattgt ggttctataa tatttgtagt gggtaaatcc
     1021 actatagata ttatggagcc tattttattg tagaaaaaaa gtcccatatg acctataatg
     1081 aaaagcgaca aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa
     1141 attactagac attaaagacc ctaatatcca gattttagac atcatcaata aggatacaca
     1201 caaggaaatc atcgccaaac tggactacga cgccccatct tgccctgagt gcggaaatca
     1261 attgaagaaa tatgactttc aaaaaccgtc taagatccct tacctcgaaa caactggtat
     1321 gccttctaga attctcctta gaaaacgccg tttcaagtgc tatcattgtt ctaaaatgat
     1381 ggttgctgaa acttctatcg tcaagaagaa tcatcaaatc cctcgtatca tcaaccaaaa
     1441 gattgctcaa aagttaattg aaaagatttc tatgaccgat attgcccatc agctttccat
     1501 ctcaacttca actgtcattc gaaagctcaa tgacttccac tttgagtgta attttagaaa
     1561 tctgcctaag attatgtctt gggacgttga aacagtccgg ggagtgactg tttcaatcgg
     1621 gagatggaga tgagcttcat tgcgcaagat tttaacaatc tcaatatcat cactgttctt
     1681 gagggaagaa cacaagctat cattcgaaat cactttctta aatatgatag agccgtccga
     1741 tgtcgcgtca aaattattac tatggatatg tttagtcctt actatgactt agctagacaa
     1801 cttttcccat gtgctaaaat cgtgttggat cgctttcaca ttgtacaaca tcttagccgt
     1861 gctatgagtc gtgtgcgtgt tcaaatcatg aatcaattgg atcgaaagtc tcatgaatac
     1921 aaggctatca agcgctactg gaagctcata caacaggata gtcgtaaact cagcgataaa
     1981 catttttatc gccctacttt tcgtatgcat ttaaccaata aagagatttt aaacaagctt
     2041 ttgagctatt cacaagactt gaaacatcac tatcagctct atcaactctt gctgtttcac
     2101 tttcagaata aggaaccgga gaaatttttc ggactcattg aggacaatct aaagcaggtt
     2161 catcctcttt ttcagactgt ctttaaaacc tttctaaagg acaaagagaa aatcgtcaac
     2221 gcccttcaac tacactattc taacgccaaa ttggaagcga ccaataatct catcaaactt
     2281 atcaagcgca atgcctttgg ttttcggaac tttgaaaact tcaaaaaacg gatttttatc
     2341 gctctgaata tcaaaaaaga aaggacaaaa tttgtccttt ctcgagctta gctgacttca
     2401 acccactaca gttgacaaag agccttaatt gtctaacttt tgcggttcac tagccttctc
     2461 tttttatatc ttagattcat ctctatatga aatgacttat aattattaga taccaattat
     2521 aagtaaaatc tttgggatct tcaatggtta accaatcaaa tgctaaatat cgaaagtgga
     2581 tatttttaaa aaactgaatc attattttct tcttttcatc gcgatgaatg aagttccaat
     2641 caaaccaagg agaccaatga tctcaagaac tagattagac gccactcctg tagatggcaa
     2701 tttcttctct gttgctacag caagcttagc tttttctttc tcctgattaa tctctggtac
     2761 acttggtttc ttaccctctg gttgagggct tggttgcata tctggttttg gagcagatgg
     2821 ctttttatcc tcagtaccgg gttgtgccgg tac
//
LOCUS       DBEJJE010000085         2347 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.85, whole genome shotgun sequence.
ACCESSION   DBEJJE010000085 DBEJJE010000000
VERSION     DBEJJE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.85"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            933..1646
                     /locus_tag="ACL3F5_001990"
     CDS             933..1646
                     /locus_tag="ACL3F5_001990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0515728.1"
                     /translation="MKILNININDFGGPENHREDFKNKFGNGKYIQEWDKLDKKETIN
                     SFISKIDEYKPDIIIIQEYDINSKECREIFEPLMVEKGYIPKSVPVKSKKRPSMTVFF
                     VKNGLGDEDISTGHDRNARAYAIQVNDLVIYGTHVPPSRDVVSFWKEINNFVQKFKNN
                     KLLLIGDFNTVNFKNNKALDNLLENPIHKIHKIWSHEGCNIPGDYVLANFDINQDGID
                     YFATKTITDHEFGVIITTD"
     gene            1712..2125
                     /locus_tag="ACL3F5_001991"
     CDS             1712..2125
                     /locus_tag="ACL3F5_001991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515729.1"
                     /translation="MTSILFSNSPNVLVYQIHKEKVIAKNITLDYSNSDFIFPVIDTY
                     IDSGNGFDYIFSHDVLVIPDPRSKQSIKTYSLYFNSDMIPISTQGEWIACFGIIKKEN
                     DMIVAGNIQLDQTLHLIKHFTITDSNNNRLPIQYT"
BASE COUNT          882 a          362 c          330 g          773 t
ORIGIN      
        1 aaactcctcg cataaaagtt ctaacttacc cattctatgg aatcttgcat tatccataat
       61 atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta gaattcgatt
      121 tgattatcct cggtttgtcc tattcttatt tcaccttact ataaaaataa ggtaaacttt
      181 tgagtgcttt gaaacattga tataatcgta ttgattaacg ttttgaggca actgaccttg
      241 tcaggttgca gccacatttg taagcgacta aagtcgcaac aactgtgtca attgcaccaa
      301 tttagtaaga aagtataaaa aaagaacacc ccgaaaggtg ctctgtataa gtatagtaat
      361 tctttcgaat taacgtttac taaattgtga tgctttacga gctttcttaa gacctggttt
      421 ggctaaccta acaactaagc tctttcgaac acgtttaatt aagctatttt taactactaa
      481 aatctcagaa attttcaact aattttaaat aattttatct aaatagggca aattcttcta
      541 caaaataaac aaatatgagt caggtatatc aacaatttgg cctatagcac aaaaaatcaa
      601 tgactaaatc aataaaccaa gcgtaccatc tctactttca aaaaagtaaa gatggtacgt
      661 tttatataag tagtaaatta aacaccaaaa tgctaaccac cttctactac attgttggaa
      721 tagaaagatt aaaatattcc ttttattttc cccaataatt aaggttgaca aatatctagt
      781 ttcttggtaa aattgaatta cataatgtgt ttttagatta catttgtatc attacctaac
      841 aaatcattat ttacttaaga agttcgtgtt tattatgcct ccttaacaca ttcaactatt
      901 gaaaaagcta aaattaaaaa ggaaatcaga atatgaaaat actaaatatt aatattaatg
      961 actttggtgg ccccgaaaac catcgtgaag attttaaaaa caaatttgga aatggcaaat
     1021 atattcaaga atgggacaag ctggataaaa aggaaacaat aaattctttt atcagtaaaa
     1081 ttgatgaata caaacctgat attattatca tacaagaata cgatataaat tctaaagagt
     1141 gtcgagaaat ttttgaacct ctgatggtgg agaaagggta tattccaaaa tcagtaccag
     1201 taaaatcaaa aaaacgtcca tctatgacag ttttctttgt taaaaatggt ctaggagacg
     1261 aagatatttc gacaggccat gatcgtaatg ccagagcata tgcaatacaa gtaaatgatt
     1321 tagtaattta cggtacacat gttccaccaa gtcgcgatgt tgtgagtttc tggaaggaaa
     1381 tcaataattt tgtacaaaaa ttcaagaaca acaagttgtt gctcattgga gattttaata
     1441 ccgtgaactt caagaataat aaagcactag ataatttatt agaaaatcct atccataaaa
     1501 tccataaaat ttggtctcat gaaggatgta atattccagg agattatgta ttggctaatt
     1561 ttgatatcaa tcaagatggg attgattatt ttgctaccaa aactattact gatcatgaat
     1621 tcggtgtgat tattacaaca gactaggcta atttcttatt acaattaagt aaataagctg
     1681 aatgatattc tagaattaaa aaggagaact tatgacatca atattatttt ctaactcccc
     1741 taatgttttg gtctaccaaa ttcacaaaga gaaggtaatc gcgaaaaata taactttaga
     1801 ttattcaaat tccgatttta tcttcccagt catagatact tatattgatt caggaaatgg
     1861 ttttgattat atttttagcc acgatgtttt agttatacct gatcctcgct caaaacaaag
     1921 cattaagaca tactcgctct attttaacag tgatatgatt ccaatttcta cacaaggaga
     1981 atggatagct tgttttggca ttataaaaaa agaaaatgac atgattgttg ctggaaatat
     2041 tcaactcgat caaacgttac atttaataaa acattttaca ataacagatt ctaacaataa
     2101 tcgtttacct atacaataca catagagaaa agcaaaagtt aaccatatta cttgaggtct
     2161 ttgataaaca tttaactttt ttaggtactt acagtagaat aaaataaaat ctggaaaagt
     2221 caaatcaatt tctagcaata ttttagaagt cacagtgtac tattctagaa ctaatccact
     2281 atagaaactg atttgtttat cgataatatt cattatcttt tgtacttttt cctaaaataa
     2341 atccatt
//
LOCUS       DBEJJE010000086         2181 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.86, whole genome shotgun sequence.
ACCESSION   DBEJJE010000086 DBEJJE010000000
VERSION     DBEJJE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.86"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            238..969
                     /locus_tag="ACL3F5_001992"
     CDS             238..969
                     /locus_tag="ACL3F5_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515730.1"
                     /translation="MLNQDLFDSLEAQRIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            984..2135
                     /locus_tag="ACL3F5_001993"
     CDS             984..2135
                     /locus_tag="ACL3F5_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0515731.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
BASE COUNT          794 a          276 c          407 g          704 t
ORIGIN      
        1 aaaggccagt tttatagtaa attgaatctg gaatattaca ctacggttcc taaaatattt
       61 tcagaaagtg atttgaattt cccaataaat ttgttcagtt tttaattgat tttactatag
      121 aagatataat tttctaaatt actctgacac agaactttaa gaaaaagcta attattgtag
      181 taatttcttt aagaaaatga tataattcat taaaaagtat ttggaggagg aagaattatg
      241 ttgaatcagg atctctttga ttcgcttgag gcacaaagaa ttgtagatac tttgatgaaa
      301 gggcaaaaag attatgtaga tgaacgtcta gaaaaaagag agacaatgat agtgtcgaat
      361 ggttatgcat ggacgcgacc taatcatatt gatactgcat ttgcatcagc agatttgttt
      421 gagtataaat tacaattagc aggacagact tggggatatt tagaatttga aacaaataca
      481 gaaaaatatg ggaaagtatt gttaattata aagggtaaga agcgacttac gaaccaattt
      541 cctttggtac aaaaaaataa gagtggctac ttatttgaat atgctcagat gaatacactt
      601 tatcttaatc aacattcttc ctacaaaaat gatgaagata gtcattcctt tccaattcag
      661 atggagttag tttctgatga aatgattcaa gaaattgaac aagctactaa aaattcgaat
      721 atcgaaaaat ttatgatttt aacttatgag gcggactcag aaaacaatat tatatctgta
      781 gatgttgtta tgcctgatgc acgaactggt cagttacact tgattcaaga tttgtctgag
      841 tatattcaat caagttcgta ccatttcgaa gaagctaaat atcaagatat tcctaatttt
      901 tcagaattat cggaaacaga agattttgaa attattccaa gaatagaaaa acaagaaggt
      961 caaaagtagt aaggagtatg taaatgttta atggtcgggt attgaaagaa ttgcggctgt
     1021 taaatggttt aagtagagca gaattagctc agagaattaa tttaacggaa caagccattt
     1081 ggcagtttga gtccaacgaa acgaaaccta aattatcaac caaaatgcat ttggccaacc
     1141 aatttcatgt tgatttaact tattttgaac aggaagaaga gagcattcga tttgattctt
     1201 ctgtaattgc ctttagaaat gcagacctag caacacggaa aacaatagat attcaaacta
     1261 tgtatttaca taaggtagat agtttgattg attattttga aagttttgta attataccta
     1321 atattacaat tcatgactta agtaatgtag tgagtgaatc ttatcataag ggagaatcca
     1381 ttgaggaatt ggctctttat gccagggaaa aattaggtat ttcaaaagat aatcatgatt
     1441 tgctttataa attagaacgt tcaggcatct atatcgtgga acgattaatt aatggccaag
     1501 ctgatgctta tagcgcatgg tcaaaattgg gaagacctta tattgtgttg ggaacgaata
     1561 aatcatctgt acgtcgaaat tttgacttag ctcatgagct aggacatatt cttttacata
     1621 aatataaaga tatgaatgaa gatggcgatc gtttggagca agaagcaaat tattttgcat
     1681 catgtttttt attgccaaaa gaagagtttt tagtcaaatt tgaagagagg gttggcaagc
     1741 gtgtcagcaa tcctgatagt tatattttat tgaagtcgga tttgaatgtt tcgatacagg
     1801 ctttagagta tcgagctttt aagttaggat tattgactcc aaagcaacat tcttactttt
     1861 atcgtcaaat tgcgcaaaaa ggttacaaaa tgattgaacc tttggatgat caaatttttg
     1921 ttaaaaaacc aagcaaagta aagagtattc tggacgtcgt tttgagtaat catctagtca
     1981 gtctagcgac tataatgtct aaacaaagta ttcgtttaca gtttataagc gaaatatttt
     2041 cagtcgaaat gaaatttttt gatcagtatc aagaagatag aagaacagat cgatttgata
     2101 acatcatccc tttgtacaaa agaaataatt tataatttaa ctgtgaaata atttcatgaa
     2161 ggacatatgg cagaaattgg a
//
LOCUS       DBEJJE010000087         2098 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.87, whole genome shotgun sequence.
ACCESSION   DBEJJE010000087 DBEJJE010000000
VERSION     DBEJJE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.87"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..295)
                     /locus_tag="ACL3F5_001994"
     CDS             complement(<1..295)
                     /locus_tag="ACL3F5_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0515732.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKQNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLK"
     gene            630..>2098
                     /gene="pcpA"
                     /locus_tag="ACL3F5_001995"
     CDS             630..>2098
                     /gene="pcpA"
                     /locus_tag="ACL3F5_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR0515733.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT          759 a          292 c          342 g          705 t
ORIGIN      
        1 gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtc gtgcgctgaa
       61 caccaacaag acgcttaaat cgtgcatcag ttagttgttt acttgcttca taattttgtt
      121 tcgcagggag tctattgact ctttggtagg tgtcaatgtt tttttcatct atcccgagaa
      181 ttattttccc gccatttgta tttgcaaatg ctgagtaggt ttcccagaaa gactctggaa
      241 gattgttttt agcttttttg tattctaaat caaccccttc aaattttaag tccatatttt
      301 tcctttacat ctgttttttg tggttctggt atttgttcaa gttgagtgat aatatagcga
      361 attgaatttc gagagttttt actcagttaa tttctttttt aacccacttt aatttctttt
      421 ttaacactgg ttaaaaaaga aattaaagtg ggttaatttt ccttgactta aaatttaaaa
      481 atgatatact gtgtttatgg agagatgaca atttataaaa tgtactactc tattctacta
      541 gataatgatt gaataaaact ttttataaca acggctagca aagttataat tttatatcta
      601 ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac tacaatatta tcattaacta
      661 cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca gatactccta
      721 gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat aatatcaaat
      781 ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat ggagttactc
      841 ctgtagagtt tgaagctggt caagatggaa aaccattcac gattcctaca aaaatcacag
      901 taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt tattatccag
      961 atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca agcataaaaa
     1021 aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt gacaaaggca
     1081 gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa gagattgaat
     1141 tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa aaattgaaaa
     1201 agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct tttgctaatt
     1261 tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga agtaatctat
     1321 ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa tcgtttgcct
     1381 cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat ccaagtcaaa
     1441 aaaatgacga aagttataaa acgcctaagg agacaaaaga acttgcatca tattcgttta
     1501 ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa atcggtactt
     1561 ttgcatttgc agatgcgatt aaacttgaag aaattagctt accaaatagt ttagaaacta
     1621 ttgaacgttt agccttttac ggtaatttag aattaaaaga acttatatta ccagataatg
     1681 ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa attaaaaagt ttaacaattg
     1741 gtaataatat caactcattg ccgtccttct tcctaagtgg cgtcttagat tcattaaagg
     1801 aaattcatat taagaataaa agtacagagt tttctgtgaa aaaagataca tttgcaattc
     1861 ctgaaactgt taagttctat gtaacatcag aacatataaa agatgttctt aaatcaaatt
     1921 tatctactag taatgatatc attgttgaaa aagtagataa tataaaacaa gaaactgatg
     1981 tagctaaacc taaaaagaat tctaatcagg gagtagttgg ttgggttaaa gacaaaggtt
     2041 tatggtatta cttaaacgaa tcaggttcaa tggctactgg ttgggttaaa gacaaagg
//
LOCUS       DBEJJE010000088         1661 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.88, whole genome shotgun sequence.
ACCESSION   DBEJJE010000088 DBEJJE010000000
VERSION     DBEJJE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.88"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            145..1491
                     /locus_tag="ACL3F5_001996"
     CDS             145..1491
                     /locus_tag="ACL3F5_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR0515734.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLITNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          489 a          361 c          326 g          485 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gttgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggctatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tgttggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc ccaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcattac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgcaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt tggtaagtta catctagttg a
//
LOCUS       DBEJJE010000089         1293 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.89, whole genome shotgun sequence.
ACCESSION   DBEJJE010000089 DBEJJE010000000
VERSION     DBEJJE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.89"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            436..831
                     /locus_tag="ACL3F5_001997"
     CDS             436..831
                     /locus_tag="ACL3F5_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515735.1"
                     /translation="MEIYTYSDFLQEKTALTFEDAHKIYNELISSFDIKDPIFLDDWT
                     MLIELASEYTEIRVKSATVSKERQDKHGTLRTSAHDAFMVQLNALKNEIESTGGNTSW
                     FDKITDDRQRQGDFANYLAYIYAVSTRSS"
     gene            905..1132
                     /locus_tag="ACL3F5_001998"
     CDS             905..1132
                     /locus_tag="ACL3F5_001998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515736.1"
                     /translation="MEHQEVIDWLKYCDENNIKPWEWDFKNCYSDTLTPDSITNFLKY
                     KNAELTNPTTFRVTKLIGKYADSDKEAFYTI"
BASE COUNT          491 a          170 c          208 g          424 t
ORIGIN      
        1 tcctccttta ttattttatt tcaatatgat tttggattat ttttttataa aatagttgac
       61 atttactttc ggattatata taatatattt agattacaaa atataaagga gttatgaata
      121 tgttcgacca agaaactttg gatctcttct atgaggaatt agaagactat tatgacgaag
      181 atgaacaagg agagattttt gacggattag atgactatta ggattgtttc cttctactac
      241 aaaattacgc ttactcggta tcttgtatgc tatattatat agctttatga attgttttaa
      301 ctgattaaaa ggtgcaaaaa aataaaaact atggctaagt tggaatatta aaaatccttg
      361 attttatttt tatataggat tataatcaaa atatagttgt ggttatacaa aaataattat
      421 ttacggaggc cctttatgga aatttacact tattctgatt ttcttcaaga aaaaactgct
      481 ttgacttttg aagatgcaca taaaatctat aatgaactaa ttagttcatt tgacataaaa
      541 gatccaattt tcctcgatga ctggacaatg ttgattgagt tagcttcaga gtatactgaa
      601 attcgtgtca aatctgcaac agtgtcaaaa gaaagacaag acaagcatgg gactcttaga
      661 acctctgctc atgatgcttt catggtacaa ttgaatgcac taaaaaacga aatcgaatct
      721 acaggaggaa atactagctg gtttgacaaa attacggatg accgacaacg gcaaggagat
      781 tttgcaaact atttagccta catttacgct gtaagcacta gatcatcata aaataaaaat
      841 actcttcaaa cagttgctta agattatcaa aacttaactt taataagacc gaaaggaaaa
      901 gcttatggaa catcaagaag ttattgattg gttgaaatat tgtgatgaaa ataatatcaa
      961 accatgggaa tgggatttta aaaattgtta ttctgatacg ctaacaccag atagtattac
     1021 aaatttttta aaatataaaa acgctgaact tacaaatcca actacttttc gagttactaa
     1081 actaattgga aagtatgctg acagtgataa ggaagcattc tatactatat aaacttttgg
     1141 gatggcaaga gtcacaagat agtatcatta gaggagaaac tataaattct tatttaacga
     1201 cgttcaagaa agctatggaa cttagttata actataattt tttgtataac gaattaaaat
     1261 tagacgaaat caaaacaata ggaaagaaag att
//
LOCUS       DBEJJE010000090         1204 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.90, whole genome shotgun sequence.
ACCESSION   DBEJJE010000090 DBEJJE010000000
VERSION     DBEJJE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.90"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..175
                     /locus_tag="ACL3F5_001999"
     CDS             <1..175
                     /locus_tag="ACL3F5_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0515737.1"
                     /translation="EDKAYNHALSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRM
                     NLIAGIINHELGF"
     gene            complement(913..1173)
                     /locus_tag="ACL3F5_002000"
     CDS             complement(913..1173)
                     /locus_tag="ACL3F5_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515738.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLVDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          405 a          224 c          200 g          375 t
ORIGIN      
        1 tgaagataaa gcctataacc atgcgctatc taaggagaga agcaaggttg agaacatctt
       61 tgccaaagta gaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt
      121 tggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat tctagttttg
      181 caggaagtct attatatatg cacagacata tgaaatcttt ttgagatagc agttatgata
      241 tatttatcca ttcacaacat cttctgtacc aatactacaa tattggtaca ttttgattac
      301 acaatcgttt caaaaaatat gatggaagcc tgagtatttt atagtaactc ccttcctatc
      361 aactagatca accagttgag tgttgaatgt tgaaacaccc tagcctcagc aaaggactat
      421 gagcagcatt tcctagccaa taggacgctc caaatcacct attctaaatc catcactagc
      481 ttggtcagta agatacagac tgcaaggcaa gactgacgtg gttgatgaga ttttggaaga
      541 gtattacaat catagattca ccagtagact tgaccgcaga tttaactata gtatattgaa
      601 actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgat
      661 caatttgtcc tgttcttgtt tcatttcact atactaaaaa accacctgaa acaaatcaag
      721 tgactagagg ataaaaacaa agactgggca aaaagttttg aaaagcaaaa aacgcataat
      781 atcaggtctt gaaaaacctt gatactatac gtttgattgt gggaagattg acttcatttt
      841 ctcctgaaat tgaagttttt tctagtttcc agatatagac gaattcaata tagccatctc
      901 gctacaatta ttttaaccat cgagaaaatt tttcagaatt tcaaaaattt cattttgatc
      961 caatgaaatg tcattatttt gaagaatagt tgacttcaca ggctctaatt ctatcacaaa
     1021 gcggtgcatg tctgctttta ccgcactact tgatgttata gccgataact tttcatctac
     1081 tagcaaggaa gctgtcaaac gggtaaggtc attcaaatgc tttttaatgg acttacttaa
     1141 accttgagca cctgtggcag agcgctccct catatccagc caagctttag ccttaaaaat
     1201 aatt
//
LOCUS       DBEJJE010000091         1198 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.91, whole genome shotgun sequence.
ACCESSION   DBEJJE010000091 DBEJJE010000000
VERSION     DBEJJE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.91"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            110..565
                     /locus_tag="ACL3F5_002001"
     CDS             110..565
                     /locus_tag="ACL3F5_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0515739.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            730..1029
                     /locus_tag="ACL3F5_002002"
     CDS             730..1029
                     /locus_tag="ACL3F5_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0515740.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          427 a          234 c          198 g          339 t
ORIGIN      
        1 aactttttta cgaaaatcta ttgaatatgc cataaaaaga ttataccaca ttgtgtacta
       61 tttttggttc atttcactat aataataacg atactagata atgaggaaaa tgcaatggca
      121 aacccaactt tcggagaaaa aagcgaatac agactatatt gctcgctatg gcgtatatgc
      181 agttatccct aatcctgaac aaaaacaaat tgttcttgtt caagaaccaa atggtgcttg
      241 gttcctacca tgtggagaaa ttgaagcagg tgaaaatcat caggaagccc taaagcgtga
      301 gttgattgaa gagcttggtt tcacagcaga aattggtacc tattacggac aagctgacga
      361 atatttctat tctcgtcatc gtgataccta ctactacaat cctgcctacc tctatgaagc
      421 aactcctttc aaagaagtac aaaagccact agaaaacttt aatcatattg cctggttccc
      481 tattgacgag gctatcaaaa accttaaacg tggtagccat aaatgggcca ttgaatcttg
      541 gaaaaaacag cataagattg actaatactc aatgaaaata aaattcaaac cacgtcagcg
      601 tcgccttacc gtactcaagt atagcctgcg gctagcttcc tagtttgctc ttttattttc
      661 attgagtata aatcaagcga ctttattcaa aaagtgctat aatagaatta gaaaatcgga
      721 ggaaatatta tgaagcttat caatacgaca aactcacact cgcaacttgt aaaaagtcag
      781 ctagaaagta ccgatgcaac ccttgttgag gtttattctg cagggaatac agatgttatt
      841 tttacccaag ctccgcttca ctatgaaatc ctcatctcaa acaaacaccg tgctattcgt
      901 gagcctgaaa tcgaaaccat tcaagaattt ttcttgaaac gtaaaattga taagacctct
      961 gttgatgaag ccaatatcaa gacactctac tcagagaaat taattggaat ttcaatccca
     1021 atcaagtaag aaaattgagt aaaaactcga tttgagagaa agtccaataa gtctttccat
     1081 aataaaacgc atagtagcaa gagtttctac acccactatt atgcgttttt atcattttga
     1141 aatctactgc taatcaatga agaagcaaag atcaaactag gcagctagtt acaagtta
//
LOCUS       DBEJJE010000092         1011 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.92, whole genome shotgun sequence.
ACCESSION   DBEJJE010000092 DBEJJE010000000
VERSION     DBEJJE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.92"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1011
                     /locus_tag="ACL3F5_002003"
                     /pseudo
     CDS             1..1011
                     /locus_tag="ACL3F5_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          301 a          221 c          174 g          315 t
ORIGIN      
        1 acgccccatc ttgccctgag tgcggaaatc aattgaagaa atatgacttt caaaaacctt
       61 ctaaaattcc ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc
      121 gattcaagtg ctatcactgt tcaaaaatga tggtcgctga aacttctatc gtcaagaaaa
      181 atcaccaaat ccctcgtatc atcaaccaaa agattgctca aaagttaatt gaaaagattt
      241 ctatgactga tattgcccat cagcttttca tctcaacttc aactgttatt cgtaagctca
      301 atgattttca ctttaaacat gatttttctt gtcttcctga gattatgtct tgggacgttg
      361 aaacagtccg ggtagtgact gtttcaatcg ggagatggag atgagcttta ttgcgcaaga
      421 ttttgacaag ctcaatatca tcactgttct tgagggaaga acacaagcta tcattcgaaa
      481 tcactttctt cgctacgata gagccgtccg atgtcgcgtc aaaatcatta ctatggatat
      541 gtttagccct tactatggct tggctaaaca gcttcgcttt caaatttcta ggctcaggct
      601 gaaacagtct cccagactgt ttcactcccg aatgctaaaa tcgttcttga tcgctttcac
      661 attgtacaac atcttagccg tgctatgagt cgtgtgcatg tccaaatcat gaatcagttt
      721 catcgcaaat cccatgaata caaggctatc aagcgctact ggaaactcat tcaacaggat
      781 agccgtaaac tgagtgataa acgtttttat cgtcctactt ttcgtatgca cttaaccaat
      841 aaagagattt taaacaagct tttgagttat tcagaagact tgaaacacca ctatcagctc
      901 ttgctgtttc acttccagaa taaggaacca gagaaatttt tcgggcttat tgaggacaat
      961 ctaaagcagg ttcatcctct ttttcagact gtctttaaaa cctttctaaa g
//
LOCUS       DBEJJE010000093          881 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.93, whole genome shotgun sequence.
ACCESSION   DBEJJE010000093 DBEJJE010000000
VERSION     DBEJJE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.93"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(8..81)
                     /locus_tag="ACL3F5_002004"
     tRNA            complement(8..81)
                     /locus_tag="ACL3F5_002004"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="ACL3F5_002005"
     tRNA            complement(95..168)
                     /locus_tag="ACL3F5_002005"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="ACL3F5_002006"
     tRNA            complement(174..247)
                     /locus_tag="ACL3F5_002006"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="ACL3F5_002007"
     tRNA            complement(263..336)
                     /locus_tag="ACL3F5_002007"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="ACL3F5_002008"
     tRNA            complement(346..431)
                     /locus_tag="ACL3F5_002008"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="ACL3F5_002009"
     tRNA            complement(439..510)
                     /locus_tag="ACL3F5_002009"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="ACL3F5_002010"
     tRNA            complement(533..605)
                     /locus_tag="ACL3F5_002010"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="ACL3F5_002011"
     tRNA            complement(624..705)
                     /locus_tag="ACL3F5_002011"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="ACL3F5_002012"
     tRNA            complement(711..783)
                     /locus_tag="ACL3F5_002012"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="ACL3F5_002013"
     tRNA            complement(808..880)
                     /locus_tag="ACL3F5_002013"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          233 a          257 c          198 g          193 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtagtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta ccttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DBEJJE010000094          838 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.94, whole genome shotgun sequence.
ACCESSION   DBEJJE010000094 DBEJJE010000000
VERSION     DBEJJE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.94"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..838
                     /locus_tag="ACL3F5_002014"
                     /pseudo
     CDS             1..838
                     /locus_tag="ACL3F5_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          326 a          149 c          161 g          202 t
ORIGIN      
        1 cgtacgatac ttcttaactg gctagcacaa tacagaaaaa aacgggtata ctattgttga
       61 gaaaacaaga gggagagtac ctaaaatggg acgtaagcca aaaaagagac ctgaagagag
      121 gacagaatta gaacatcttc aagcagaaaa tgagtacctg agagcggaga atgccatcct
      181 aaaaaagtta agagaactcc gattgaagga ggaaaaagag aaagaagaaa gacagaaatt
      241 gttcaagaat taatgactga gttttcgtta gatattcttc taaaagccat taaactagct
      301 cgttcgacct actactatca cttgaaacag ctagacaaac cagataagga ccaagagctt
      361 aaagctgaaa ttcaatccat ttttatcgaa cacaagggaa attatgctta tcgtcggatt
      421 tatttagaac taagaaatcg tggttatctg gtaaatcata aaagagttca aggcttgatg
      481 aaagtactca atttacaagc taaaatgcga cagaaacgaa aatattcttc tcataaagga
      541 gacgttggta agaaagcaga gaatctcatt caaggccaat ttgaaggctc taaaacaatg
      601 gaacagtgct acacagatgt gactgaattt gccattccag taagtactca aaagctttac
      661 ttatcaccag ttttagatgg ttttaacagc gaaattatcg cctataatct ttcaacttca
      721 cccaacttag aacaagtaca aacaatgttg gaacaggcat tcacagagaa gcactacgag
      781 aatacgattc tccatagtga ccaaggctgg caatatcaac acgattctta tcatcagt
//
LOCUS       DBEJJE010000095          777 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.95, whole genome shotgun sequence.
ACCESSION   DBEJJE010000095 DBEJJE010000000
VERSION     DBEJJE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.95"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            16..86
                     /locus_tag="ACL3F5_002015"
     tRNA            16..86
                     /locus_tag="ACL3F5_002015"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="ACL3F5_002016"
     tRNA            122..195
                     /locus_tag="ACL3F5_002016"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="ACL3F5_002017"
     tRNA            202..289
                     /locus_tag="ACL3F5_002017"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(496..>777)
                     /locus_tag="ACL3F5_002018"
     CDS             complement(496..>777)
                     /locus_tag="ACL3F5_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0515741.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          203 a          130 c          175 g          269 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa
      421 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tggctctttg tcaactgtag
      481 tgggttgaaa aaaagctaag ctcgagaaag gacaaatttt gtcctttctt ttttgatgtt
      541 caaagcgata aaaatccttt ttttgaagtt ttcaaagttc cgaaatccaa aggcgtttcg
      601 tttgataagt ttgatgagat tatttgtcgc ttccagtttg gcgttagaat agtgtagttg
      661 aagggcgttg acaatctttt ctttatcttt gaggaaggtt ttaaagacag tctgaaaaat
      721 aggatgaacc tgcttcagat tgtcctcaat aagcccgaaa aatttctctg gttcctt
//
LOCUS       DBEJJE010000096          739 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.96, whole genome shotgun sequence.
ACCESSION   DBEJJE010000096 DBEJJE010000000
VERSION     DBEJJE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.96"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            90..731
                     /locus_tag="ACL3F5_002019"
                     /pseudo
     CDS             90..731
                     /locus_tag="ACL3F5_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT          294 a           92 c          140 g          213 t
ORIGIN      
        1 aaaatttcat aaaaatggtt accaaaggcg atagaagaaa aactatcgtc tttttctttg
       61 caaattttta agaagggagg tgatcttgca tggactttga atatttttat aacagagaag
      121 cggaaagatt taacttctta aaagtaccgg agatattagt tgatagagaa gaatttcggg
      181 gcttatcagc agaagcaatt atcctttatt ccatacttct taaatagaca ggaatgtcat
      241 ttaagaataa ctggatagac aaggaaggca gagtatttat ctattttact gtcgaagaaa
      301 ttatgaaaag aagaaatatc tcaaagccaa ctgccataaa aacattagat gagcttgatg
      361 taaaaaaagg aataggactg atcgaaagag taaggcttgg acttggtaag ccgaacatca
      421 tttatgttaa agactttatg agtatatttc aggtaaaaga aaatgactta cagaagtcaa
      481 aaaacttaac ttcagaagta aaagatttta acctcagaag taaagaaaat gaacttcaag
      541 aggttaagaa ccttgactct aactatatag agaataataa gagtaagtat agtaagagag
      601 aatatagttt tggtgaaaac ggacttggaa catttcaaaa tgtgttttta gctgctgaag
      661 atatatcgga tttacaaatc ataatgaact cacagcttga gaattacatt agacttcctg
      721 caaaactaga attctagtt
//
LOCUS       DBEJJE010000097          694 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.97, whole genome shotgun sequence.
ACCESSION   DBEJJE010000097 DBEJJE010000000
VERSION     DBEJJE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.97"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            109..471
                     /locus_tag="ACL3F5_002020"
     CDS             109..471
                     /locus_tag="ACL3F5_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0515742.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          225 a           94 c          129 g          246 t
ORIGIN      
        1 tgttttgagc tgactacgtc agttccatct acaacctcaa aacagtgttt tgagcaacct
       61 gcggctagtt tcctagtttg ctctttggtt ttcattgagt ataacacatt gttagaagtt
      121 ggtttaaatt ccctaatcag tttgttcaca tttaccttcg atatattata tcccatagtt
      181 aaggttggtc atacagatga ttatagtcat ggagccgtaa aacttagtgt ttctttagtt
      241 gacaaagatg ccatgaaaaa aatatctgta actgtaatag gatattttga aataaatata
      301 gatgaaaata tcaccgatat tctatacgta aatggtactg ctattcttta tccttattta
      361 cgttctattg tttcaacagt ttcggcaatt gatagcagtg aagcaatgtt gctacctacc
      421 attaatgttt tagagttact agataaatct caaccttttg aagaagaata atttattagc
      481 tcactaaatt gagggtaagg aaaagtaaaa gcagtaagaa aaatgtcttg cattatacag
      541 caaccttttg ggaatgagta gatggattga ataaaatttg attaagagtg gatgatttat
      601 ctgtagatta ttattggaca gttagtcttg aagtagtcta agaattaggt tataatcagt
      661 agaagccttg ctaataatga ggaggttagt ttat
//
LOCUS       DBEJJE010000098          496 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.98, whole genome shotgun sequence.
ACCESSION   DBEJJE010000098 DBEJJE010000000
VERSION     DBEJJE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.98"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>496
                     /locus_tag="ACL3F5_002021"
     CDS             <1..>496
                     /locus_tag="ACL3F5_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515743.1"
                     /translation="EFQVRVSSEAIFYFEKLKKMYSNNSKFELTRSQILTRAFEETKI
                     ITNWTSIINDTETISLEYLEYQKGYGTNVKVQISDEVEKGIRELKILLPNFTTTRSVT
                     IGVAVKFMLKGAIILNKTGKINTNKNLSTMEAIEELKQNLQDIVAPINYNVLENIMDN
                     FKNN"
BASE COUNT          219 a           57 c           74 g          146 t
ORIGIN      
        1 tggaatttca agttagagta tcaagtgaag ctatttttta ttttgaaaaa ttgaaaaaaa
       61 tgtattcaaa taattctaaa tttgaactca cgcgtagtca aatactcact agagctttcg
      121 aagaaactaa aattattaca aattggacat ctatcattaa tgatacagaa acaatatcac
      181 tagaatattt agaatatcaa aaaggttacg gaacaaatgt taaagtacaa ataagtgatg
      241 aggttgagaa gggaattaga gaattaaaaa tactattacc aaattttaca actacgagaa
      301 gtgtaaccat cggcgttgct gttaaattta tgttaaaagg agctattata ttaaataaaa
      361 ctggaaagat aaatacaaat aaaaatttgt ctaccatgga agcaattgag gaattaaaac
      421 aaaacttgca agatatagtt gctcccataa attataatgt actagaaaac ataatggaca
      481 attttaaaaa taacat
//
LOCUS       DBEJJE010000099          449 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.99, whole genome shotgun sequence.
ACCESSION   DBEJJE010000099 DBEJJE010000000
VERSION     DBEJJE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.99"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..449
                     /locus_tag="ACL3F5_002022"
                     /pseudo
     CDS             1..449
                     /locus_tag="ACL3F5_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          132 a           92 c           88 g          137 t
ORIGIN      
        1 ctagaattct ccttagaaag cgtcgaaagc gtcgtttcaa gtgctatcat tgttctaaaa
       61 tgatggtcgc tgaaacttct atcgtcaaga aaaatcacca aattcctcgt attatcaacc
      121 aaaaaattgc gcaaaagttg attgagaaga tttctatgac cgatattgct catcagctgg
      181 ccatttcaac ttcaactgtc attcgaaagc tcaatgattc tcactttgag catgattttt
      241 cgcgtcttcc tgagattatg tcctgggacg ttgaaacagt ccggggagtg actgtttcaa
      301 tcgggagatg gagatgagct ttattgcgca agattttaac aatctcaata tcatcactgt
      361 tcttgaaggt agaacacaag ctgtcatccg agatcacttt cttaaatatg atagagccgt
      421 ccgatgtcgc gtcaaaatca ttactatgg
//
LOCUS       DBEJJE010000100          438 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 678088
            SAMN38261708-rid24806673.denovo.100, whole genome shotgun sequence.
ACCESSION   DBEJJE010000100 DBEJJE010000000
VERSION     DBEJJE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261708
            Sequence Read Archive: SRR26833700
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576084.1
            Genome Coverage       :: 197x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:56:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,022
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,859
            CDSs (with protein)               :: 1,859
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 59 of 119
            Pseudo Genes (internal stop)      :: 44 of 119
            Pseudo Genes (multiple problems)  :: 34 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261708-rid24806673.denovo.100"
                     /strain="GPSC61"
                     /isolate="678088"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            202..438
                     /locus_tag="ACL3F5_000614"
                     /pseudo
     CDS             202..438
                     /locus_tag="ACL3F5_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          144 a           76 c           86 g          132 t
ORIGIN      
        1 cttttaaaag actctcgtac agctaaatat cataaacgcc ttcaaatcgt tctatttcgt
       61 ctgatgggca aatcttataa agagattata gaacttttat agtggtttga aataagatgt
      121 gaacaactct atcaggaaag tcaaactaat ttatagaaat attttagcag ccaaggtgta
      181 ctgttataga ttcaatacac tttagactgt aatcaaacaa cgatttggcg aaatgtaaaa
      241 aatatgagga gttcggactc gactctctcc ttcaagaaac acgtggtggt cgtaaccatg
      301 cttatatgac ggttgagcaa gagaaagtct ttcttgcccg ccatttgaag gctacagagg
      361 caggagaatt tgttacaatt gatgccttat ttcaggctta taaaaaggag ttaggtcgtt
      421 cctacacacg tgatgcct
//
